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 | Fusion Gene Summary |
| Fusion Gene ORF analysis |
| Fusion Genomic Features |
| Fusion Protein Features |
| Fusion Gene Sequence |
| Fusion Gene PPI analysis |
| Related Drugs |
| Related Diseases |
Fusion gene:SMAD2-C10orf90 (FusionGDB2 ID:83766) |
Fusion Gene Summary for SMAD2-C10orf90 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: SMAD2-C10orf90 | Fusion gene ID: 83766 | Hgene | Tgene | Gene symbol | SMAD2 | C10orf90 | Gene ID | 4087 | 118611 |
| Gene name | SMAD family member 2 | chromosome 10 open reading frame 90 | |
| Synonyms | JV18|JV18-1|MADH2|MADR2|hMAD-2|hSMAD2 | FATS|bA422P15.2 | |
| Cytomap | 18q21.1 | 10q26.2 | |
| Type of gene | protein-coding | protein-coding | |
| Description | mothers against decapentaplegic homolog 2MAD homolog 2SMAD, mothers against DPP homolog 2Sma- and Mad-related protein 2mother against DPP homolog 2 | (E2-independent) E3 ubiquitin-conjugating enzyme FATSE2/E3 hybrid ubiquitin-protein ligase FATScentrosomal protein C10orf90fragile-site associated tumor suppressor homolog | |
| Modification date | 20200322 | 20200313 | |
| UniProtAcc | . | Q96M02 | |
| Ensembl transtripts involved in fusion gene | ENST00000262160, ENST00000356825, ENST00000402690, ENST00000586040, ENST00000591214, ENST00000587353, | ENST00000356858, ENST00000368674, ENST00000392694, ENST00000480379, ENST00000284694, ENST00000454341, ENST00000544758, | |
| Fusion gene scores | * DoF score | 21 X 18 X 8=3024 | 3 X 2 X 2=12 |
| # samples | 23 | 3 | |
| ** MAII score | log2(23/3024*10)=-3.7167523732767 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(3/12*10)=1.32192809488736 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | |
| Context | PubMed: SMAD2 [Title/Abstract] AND C10orf90 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Most frequent breakpoint | SMAD2(45394694)-C10orf90(128202508), # samples:3 | ||
| Anticipated loss of major functional domain due to fusion event. | SMAD2-C10orf90 seems lost the major protein functional domain in Hgene partner, which is a CGC due to the frame-shifted ORF. SMAD2-C10orf90 seems lost the major protein functional domain in Hgene partner, which is a tumor suppressor due to the frame-shifted ORF. | ||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Hgene | SMAD2 | GO:0007179 | transforming growth factor beta receptor signaling pathway | 8752209|9389648|9732876|18548003 |
| Hgene | SMAD2 | GO:0007182 | common-partner SMAD protein phosphorylation | 16806156 |
| Hgene | SMAD2 | GO:0007183 | SMAD protein complex assembly | 9111321 |
| Hgene | SMAD2 | GO:0045893 | positive regulation of transcription, DNA-templated | 9311995|9389648|9732876 |
| Hgene | SMAD2 | GO:0045944 | positive regulation of transcription by RNA polymerase II | 9389648 |
| Hgene | SMAD2 | GO:0070723 | response to cholesterol | 17878231 |
| Fusion gene breakpoints across SMAD2 (5'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
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| Fusion gene breakpoints across C10orf90 (3'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
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| Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Source | Disease | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| ChimerDB4 | LUAD | TCGA-97-7937-01A | SMAD2 | chr18 | 45394694 | - | C10orf90 | chr10 | 128202508 | - |
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Fusion Gene ORF analysis for SMAD2-C10orf90 |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| 5CDS-5UTR | ENST00000262160 | ENST00000356858 | SMAD2 | chr18 | 45394694 | - | C10orf90 | chr10 | 128202508 | - |
| 5CDS-5UTR | ENST00000262160 | ENST00000368674 | SMAD2 | chr18 | 45394694 | - | C10orf90 | chr10 | 128202508 | - |
| 5CDS-5UTR | ENST00000262160 | ENST00000392694 | SMAD2 | chr18 | 45394694 | - | C10orf90 | chr10 | 128202508 | - |
| 5CDS-5UTR | ENST00000356825 | ENST00000356858 | SMAD2 | chr18 | 45394694 | - | C10orf90 | chr10 | 128202508 | - |
| 5CDS-5UTR | ENST00000356825 | ENST00000368674 | SMAD2 | chr18 | 45394694 | - | C10orf90 | chr10 | 128202508 | - |
| 5CDS-5UTR | ENST00000356825 | ENST00000392694 | SMAD2 | chr18 | 45394694 | - | C10orf90 | chr10 | 128202508 | - |
| 5CDS-5UTR | ENST00000402690 | ENST00000356858 | SMAD2 | chr18 | 45394694 | - | C10orf90 | chr10 | 128202508 | - |
| 5CDS-5UTR | ENST00000402690 | ENST00000368674 | SMAD2 | chr18 | 45394694 | - | C10orf90 | chr10 | 128202508 | - |
| 5CDS-5UTR | ENST00000402690 | ENST00000392694 | SMAD2 | chr18 | 45394694 | - | C10orf90 | chr10 | 128202508 | - |
| 5CDS-5UTR | ENST00000586040 | ENST00000356858 | SMAD2 | chr18 | 45394694 | - | C10orf90 | chr10 | 128202508 | - |
| 5CDS-5UTR | ENST00000586040 | ENST00000368674 | SMAD2 | chr18 | 45394694 | - | C10orf90 | chr10 | 128202508 | - |
| 5CDS-5UTR | ENST00000586040 | ENST00000392694 | SMAD2 | chr18 | 45394694 | - | C10orf90 | chr10 | 128202508 | - |
| 5CDS-5UTR | ENST00000591214 | ENST00000356858 | SMAD2 | chr18 | 45394694 | - | C10orf90 | chr10 | 128202508 | - |
| 5CDS-5UTR | ENST00000591214 | ENST00000368674 | SMAD2 | chr18 | 45394694 | - | C10orf90 | chr10 | 128202508 | - |
| 5CDS-5UTR | ENST00000591214 | ENST00000392694 | SMAD2 | chr18 | 45394694 | - | C10orf90 | chr10 | 128202508 | - |
| 5CDS-intron | ENST00000262160 | ENST00000480379 | SMAD2 | chr18 | 45394694 | - | C10orf90 | chr10 | 128202508 | - |
| 5CDS-intron | ENST00000356825 | ENST00000480379 | SMAD2 | chr18 | 45394694 | - | C10orf90 | chr10 | 128202508 | - |
| 5CDS-intron | ENST00000402690 | ENST00000480379 | SMAD2 | chr18 | 45394694 | - | C10orf90 | chr10 | 128202508 | - |
| 5CDS-intron | ENST00000586040 | ENST00000480379 | SMAD2 | chr18 | 45394694 | - | C10orf90 | chr10 | 128202508 | - |
| 5CDS-intron | ENST00000591214 | ENST00000480379 | SMAD2 | chr18 | 45394694 | - | C10orf90 | chr10 | 128202508 | - |
| Frame-shift | ENST00000262160 | ENST00000284694 | SMAD2 | chr18 | 45394694 | - | C10orf90 | chr10 | 128202508 | - |
| Frame-shift | ENST00000262160 | ENST00000454341 | SMAD2 | chr18 | 45394694 | - | C10orf90 | chr10 | 128202508 | - |
| Frame-shift | ENST00000262160 | ENST00000544758 | SMAD2 | chr18 | 45394694 | - | C10orf90 | chr10 | 128202508 | - |
| In-frame | ENST00000356825 | ENST00000284694 | SMAD2 | chr18 | 45394694 | - | C10orf90 | chr10 | 128202508 | - |
| In-frame | ENST00000356825 | ENST00000454341 | SMAD2 | chr18 | 45394694 | - | C10orf90 | chr10 | 128202508 | - |
| In-frame | ENST00000356825 | ENST00000544758 | SMAD2 | chr18 | 45394694 | - | C10orf90 | chr10 | 128202508 | - |
| In-frame | ENST00000402690 | ENST00000284694 | SMAD2 | chr18 | 45394694 | - | C10orf90 | chr10 | 128202508 | - |
| In-frame | ENST00000402690 | ENST00000454341 | SMAD2 | chr18 | 45394694 | - | C10orf90 | chr10 | 128202508 | - |
| In-frame | ENST00000402690 | ENST00000544758 | SMAD2 | chr18 | 45394694 | - | C10orf90 | chr10 | 128202508 | - |
| In-frame | ENST00000586040 | ENST00000284694 | SMAD2 | chr18 | 45394694 | - | C10orf90 | chr10 | 128202508 | - |
| In-frame | ENST00000586040 | ENST00000454341 | SMAD2 | chr18 | 45394694 | - | C10orf90 | chr10 | 128202508 | - |
| In-frame | ENST00000586040 | ENST00000544758 | SMAD2 | chr18 | 45394694 | - | C10orf90 | chr10 | 128202508 | - |
| In-frame | ENST00000591214 | ENST00000284694 | SMAD2 | chr18 | 45394694 | - | C10orf90 | chr10 | 128202508 | - |
| In-frame | ENST00000591214 | ENST00000454341 | SMAD2 | chr18 | 45394694 | - | C10orf90 | chr10 | 128202508 | - |
| In-frame | ENST00000591214 | ENST00000544758 | SMAD2 | chr18 | 45394694 | - | C10orf90 | chr10 | 128202508 | - |
| intron-3CDS | ENST00000587353 | ENST00000284694 | SMAD2 | chr18 | 45394694 | - | C10orf90 | chr10 | 128202508 | - |
| intron-3CDS | ENST00000587353 | ENST00000454341 | SMAD2 | chr18 | 45394694 | - | C10orf90 | chr10 | 128202508 | - |
| intron-3CDS | ENST00000587353 | ENST00000544758 | SMAD2 | chr18 | 45394694 | - | C10orf90 | chr10 | 128202508 | - |
| intron-5UTR | ENST00000587353 | ENST00000356858 | SMAD2 | chr18 | 45394694 | - | C10orf90 | chr10 | 128202508 | - |
| intron-5UTR | ENST00000587353 | ENST00000368674 | SMAD2 | chr18 | 45394694 | - | C10orf90 | chr10 | 128202508 | - |
| intron-5UTR | ENST00000587353 | ENST00000392694 | SMAD2 | chr18 | 45394694 | - | C10orf90 | chr10 | 128202508 | - |
| intron-intron | ENST00000587353 | ENST00000480379 | SMAD2 | chr18 | 45394694 | - | C10orf90 | chr10 | 128202508 | - |
| ORFfinder result based on the fusion transcript sequence of in-frame fusion genes. |
| Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | Seq length (transcript) | BP loci (transcript) | Predicted start (transcript) | Predicted stop (transcript) | Seq length (amino acids) |
| ENST00000402690 | SMAD2 | chr18 | 45394694 | - | ENST00000454341 | C10orf90 | chr10 | 128202508 | - | 3692 | 1050 | 395 | 2836 | 813 |
| ENST00000402690 | SMAD2 | chr18 | 45394694 | - | ENST00000284694 | C10orf90 | chr10 | 128202508 | - | 3983 | 1050 | 395 | 3127 | 910 |
| ENST00000402690 | SMAD2 | chr18 | 45394694 | - | ENST00000544758 | C10orf90 | chr10 | 128202508 | - | 3427 | 1050 | 395 | 3127 | 910 |
| ENST00000356825 | SMAD2 | chr18 | 45394694 | - | ENST00000454341 | C10orf90 | chr10 | 128202508 | - | 3605 | 963 | 398 | 2749 | 783 |
| ENST00000356825 | SMAD2 | chr18 | 45394694 | - | ENST00000284694 | C10orf90 | chr10 | 128202508 | - | 3896 | 963 | 398 | 3040 | 880 |
| ENST00000356825 | SMAD2 | chr18 | 45394694 | - | ENST00000544758 | C10orf90 | chr10 | 128202508 | - | 3340 | 963 | 398 | 3040 | 880 |
| ENST00000586040 | SMAD2 | chr18 | 45394694 | - | ENST00000454341 | C10orf90 | chr10 | 128202508 | - | 3262 | 620 | 55 | 2406 | 783 |
| ENST00000586040 | SMAD2 | chr18 | 45394694 | - | ENST00000284694 | C10orf90 | chr10 | 128202508 | - | 3553 | 620 | 55 | 2697 | 880 |
| ENST00000586040 | SMAD2 | chr18 | 45394694 | - | ENST00000544758 | C10orf90 | chr10 | 128202508 | - | 2997 | 620 | 55 | 2697 | 880 |
| ENST00000591214 | SMAD2 | chr18 | 45394694 | - | ENST00000454341 | C10orf90 | chr10 | 128202508 | - | 3303 | 661 | 96 | 2447 | 783 |
| ENST00000591214 | SMAD2 | chr18 | 45394694 | - | ENST00000284694 | C10orf90 | chr10 | 128202508 | - | 3594 | 661 | 96 | 2738 | 880 |
| ENST00000591214 | SMAD2 | chr18 | 45394694 | - | ENST00000544758 | C10orf90 | chr10 | 128202508 | - | 3038 | 661 | 96 | 2738 | 880 |
| DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated. |
| Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | No-coding score | Coding score |
| ENST00000402690 | ENST00000454341 | SMAD2 | chr18 | 45394694 | - | C10orf90 | chr10 | 128202508 | - | 0.000895673 | 0.9991043 |
| ENST00000402690 | ENST00000284694 | SMAD2 | chr18 | 45394694 | - | C10orf90 | chr10 | 128202508 | - | 0.000507415 | 0.9994925 |
| ENST00000402690 | ENST00000544758 | SMAD2 | chr18 | 45394694 | - | C10orf90 | chr10 | 128202508 | - | 0.000665725 | 0.9993343 |
| ENST00000356825 | ENST00000454341 | SMAD2 | chr18 | 45394694 | - | C10orf90 | chr10 | 128202508 | - | 0.001657362 | 0.99834263 |
| ENST00000356825 | ENST00000284694 | SMAD2 | chr18 | 45394694 | - | C10orf90 | chr10 | 128202508 | - | 0.00089603 | 0.99910396 |
| ENST00000356825 | ENST00000544758 | SMAD2 | chr18 | 45394694 | - | C10orf90 | chr10 | 128202508 | - | 0.001181378 | 0.9988186 |
| ENST00000586040 | ENST00000454341 | SMAD2 | chr18 | 45394694 | - | C10orf90 | chr10 | 128202508 | - | 0.001199088 | 0.9988009 |
| ENST00000586040 | ENST00000284694 | SMAD2 | chr18 | 45394694 | - | C10orf90 | chr10 | 128202508 | - | 0.000674211 | 0.99932575 |
| ENST00000586040 | ENST00000544758 | SMAD2 | chr18 | 45394694 | - | C10orf90 | chr10 | 128202508 | - | 0.000845305 | 0.9991547 |
| ENST00000591214 | ENST00000454341 | SMAD2 | chr18 | 45394694 | - | C10orf90 | chr10 | 128202508 | - | 0.001362394 | 0.9986376 |
| ENST00000591214 | ENST00000284694 | SMAD2 | chr18 | 45394694 | - | C10orf90 | chr10 | 128202508 | - | 0.000758918 | 0.9992411 |
| ENST00000591214 | ENST00000544758 | SMAD2 | chr18 | 45394694 | - | C10orf90 | chr10 | 128202508 | - | 0.001003926 | 0.9989961 |
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Fusion Genomic Features for SMAD2-C10orf90 |
| FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints. |
| Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | 1-p | p (fusion gene breakpoint) |
| Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page. |
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| Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page. |
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Fusion Protein Features for SMAD2-C10orf90 |
| Four levels of functional features of fusion genes Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr18:45394694/chr10:128202508) - FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels. - How to search 1. Put your fusion gene symbol. 2. Press the tab key until there will be shown the breakpoint information filled. 4. Go down and press 'Search' tab twice. 4. Go down to have the hyperlink of the search result. 5. Click the hyperlink. 6. See the FGviewer result for your fusion gene. |
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| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| . | C10orf90 |
| FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}. | FUNCTION: Tumor suppressor that is required to sustain G2/M checkpoint after DNA damage. Acts as a p53/TP53 activator by inhibiting MDM2 binding to p53/TP53 and stimulating non-proteolytic polyubiquitination of p53/TP53. Exhibits ubiquitin ligase (E3) activity and assemble ubiquitin polymers through 'Lys-11'- (K11-), 'Lys-29'- (K29-) and 'Lys-63'- (K63)-linkages, independently of the ubiquitin-conjugating enzyme (E2). Promotes p53/TP53-dependent transcription of CDKN1A/p21, leading to robust checkpoint response. Mediates CDKN1A/p21 protein stability in a ubiquitin-independent manner. Interacts with HDAC1 and prevents binding of HDAC1 to CDKN1A/p21 and facilitates the acetylation and stabilization of CDKN1A/p21 (By similarity). May have a role in the assembly of primary cilia (Probable). {ECO:0000250|UniProtKB:D2J0Y4, ECO:0000305|PubMed:20844083}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | SMAD2 | chr18:45394694 | chr10:128202508 | ENST00000262160 | - | 5 | 11 | 10_176 | 218 | 468.0 | Domain | MH1 |
| Hgene | SMAD2 | chr18:45394694 | chr10:128202508 | ENST00000356825 | - | 4 | 10 | 10_176 | 188 | 438.0 | Domain | MH1 |
| Hgene | SMAD2 | chr18:45394694 | chr10:128202508 | ENST00000402690 | - | 5 | 11 | 10_176 | 218 | 468.0 | Domain | MH1 |
| Hgene | SMAD2 | chr18:45394694 | chr10:128202508 | ENST00000586040 | - | 3 | 9 | 10_176 | 188 | 438.0 | Domain | MH1 |
| Tgene | C10orf90 | chr18:45394694 | chr10:128202508 | ENST00000284694 | 0 | 9 | 663_666 | 7 | 700.0 | Compositional bias | Note=Poly-Lys | |
| Tgene | C10orf90 | chr18:45394694 | chr10:128202508 | ENST00000454341 | 0 | 8 | 663_666 | 7 | 603.0 | Compositional bias | Note=Poly-Lys | |
| Tgene | C10orf90 | chr18:45394694 | chr10:128202508 | ENST00000480379 | 0 | 6 | 663_666 | 0 | 104.0 | Compositional bias | Note=Poly-Lys | |
| Tgene | C10orf90 | chr18:45394694 | chr10:128202508 | ENST00000284694 | 0 | 9 | 571_699 | 7 | 700.0 | Region | ALMS motif | |
| Tgene | C10orf90 | chr18:45394694 | chr10:128202508 | ENST00000454341 | 0 | 8 | 571_699 | 7 | 603.0 | Region | ALMS motif | |
| Tgene | C10orf90 | chr18:45394694 | chr10:128202508 | ENST00000480379 | 0 | 6 | 571_699 | 0 | 104.0 | Region | ALMS motif |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | SMAD2 | chr18:45394694 | chr10:128202508 | ENST00000262160 | - | 5 | 11 | 274_467 | 218 | 468.0 | Domain | MH2 |
| Hgene | SMAD2 | chr18:45394694 | chr10:128202508 | ENST00000356825 | - | 4 | 10 | 274_467 | 188 | 438.0 | Domain | MH2 |
| Hgene | SMAD2 | chr18:45394694 | chr10:128202508 | ENST00000402690 | - | 5 | 11 | 274_467 | 218 | 468.0 | Domain | MH2 |
| Hgene | SMAD2 | chr18:45394694 | chr10:128202508 | ENST00000586040 | - | 3 | 9 | 274_467 | 188 | 438.0 | Domain | MH2 |
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Fusion Gene Sequence for SMAD2-C10orf90 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones. |
| >83766_83766_1_SMAD2-C10orf90_SMAD2_chr18_45394694_ENST00000356825_C10orf90_chr10_128202508_ENST00000284694_length(transcript)=3896nt_BP=963nt GCCGGGAGGCGGGGCGGGCCGTAGGCAAAGGGAGGTGGGGAGGCGGTGGCCGGCGACTCCCCGCGCCCCGCTCGCCCCCCGGCCCTTCCC GCGGTGCTCGGCCTCGTTCCTTTCCTCCTCCGCTCCCTCCGTCTTCCATACCCGCCCCGCGCGGCTTTCGGCCGGCGTGCCTCGCGCCCT AACGGGCGGCTGGAGGCGCCAATCAGCGGGCGGCAGGGTGCCAGCCCCGGGGCTGCGCCGGCGAATCGGCGGGGCCCGCGGCCCAGGGTG GCAGGCGGGTCTACCCGCGCGGCCGCGGCGGCGGAGAAGCAGCTCGCCAGCCAGCAGCCCGCCAGCCGCCGGGAGGTTCGATACAAGAGG CTGTTTTCCTAGCGTGGCTTGCTGCCTTTGGTAAGAACATGTCGTCCATCTTGCCATTCACGCCGCCAGTTGTGAAGAGACTGCTGGGAT GGAAGAAGTCAGCTGGTGGGTCTGGAGGAGCAGGCGGAGGAGAGCAGAATGGGCAGGAAGAAAAGTGGTGTGAGAAAGCAGTGAAAAGTC TGGTGAAGAAGCTAAAGAAAACAGGACGATTAGATGAGCTTGAGAAAGCCATCACCACTCAAAACTGTAATACTAAATGTGTTACCATAC CAAGGTCTCTTGATGGTCGTCTCCAGGTATCCCATCGAAAAGGATTGCCACATGTTATATATTGCCGATTATGGCGCTGGCCTGATCTTC ACAGTCATCATGAACTCAAGGCAATTGAAAACTGCGAATATGCTTTTAATCTTAAAAAGGATGAAGTATGTGTAAACCCTTACCACTATC AGAGAGTTGAGACACCAGTTTTGCCTCCAGTATTAGTGCCCCGACACACCGAGATCCTAACAGAACTTCCGCCTCTGGATGACTATACTC ACTCCATTCCAGAAAACACTAACTTCCCAGCAGGAATTGAGCCACAGAGTAATTATATTCCAGGATTACGGGACAGCTACCACAGTAGAA GAGATCAAATTGCCCTTAAAAATCTCCAGTCTGATGTCACAGAGGCAAAATCTGACTTCACCAAGGAGACCCTGGCATCACAAAACACAA AAATGATTTCATCCATAGTCATCTCCCAGATGATTGATGAGAATAAGTCAAGAGAAAACAGGGCCTCCTTGCCCCTACCGTGTGCCATTG CTCAGTCTCGTGCACATCACGCCAAGCAATCTCTGGCTAACCGCAGCGGAGTCAACATTCACAGAGCATTTGCGTTACTTCCGGGCAGAT TAGGAATCCCGGCACCGTCAGATGAGCGAGGACCTGAGGCAGAGCTGCCGCCCAAAGAGGAGAGACCCTGTGGGGGCCCCCGCAGAGGGT TTGCATCCATCACCATCACGGCCAGACGCGTGGGCCCCCCAGCCCGCGCCCTGGTGTGGGGGACTGCTGGGGACTCTCTGTGCCCCAAGT GCAGGGCTGAGGACACACTGTTCCAGGCGCCCCCGGCTCTGGCCAATGGCGCCCATCCAGGTCGGCATCAGAGATCTTTTGCCTGCACAG AGTTCTCCAGAAACAGCTCCGTGGTGCGGCTGAAGGTTCCCGAGGCCCACACTGGGTTGTGTGAGAGACGCAAGTACTGGGTCACCCATG CAGACGACAAAGAGACCAGTTTTTCTCCAGACACCCCACTGTCAGGAAAGAGCCCGCTGGTGTTCAGTTCCTGTGTCCACCTCAGGGTGT CTCAGCAGTGTCCAGATTCAATCTATTACGTAGACAAGTCTCTCTCCGTCCCCATTGAGCCACCTCAAATTGCCAGCCCCAAAATGCACA GATCCGTCCTGTCGCTCAACCTCAATTGTAGTTCCCACAGATTAACAGCAGATGGAGTAGATGGCCTAGTGAACAGAGAGCCAATAAGCG AAGCCCTGAAGCAGGAGCTCCTGGAGGGAGACCAGGACCTCGTAGGCCAGCGCTGGAACCCAGGTTTACAAGAAAGTCACTTGAAGGAAA CCCCATCGTTGAGGCGGGTGCATTTGGGGACCGGCGCTTGTCCTTGGAGTGGTTCTTTTCCATTGGAAAACACAGAATTGGCAAATGTGG GAGCTAACCAAGTCACTGTAAGAAAAGGGGAAAAGGACCATACAACTCATTGTCACGCCAGCGATCATGCCAACCAACTGTCCATTCACA TTCCTGGCTGGAGTTACAGGGCAGTACACACAAAAGTATTTTCTGGAAGCAGCAAGAGGCAACAAGGAGAAGTATGTATGACTGTGTCTG CTCCTCCAGTGGAACAGAAGCCCACTAGACATTTCCTTCCCATTGGGGATAGCTCTCCAAGCGATGACTGTCTGTCTAGAGACCTTTCTG AGCCCACAGAGAGACGACATCAAAGCTTCCTGAAACCCAGAATCCTTTTTCCTGGGTTTCTTTGCCCCTTACAAGATGTATGTGCATCTC TGCAGGAAGACAATGGTGTTCAGATAGAAAGCAAGTTCCCCAAAGGAGATTACACATGCTGTGACTTGGTTGTAAAAATAAAGGAATGTA AGAAGAGTGAGGACCCCACCACACCTGAGCCCTCCCCAGCAGCACCCTCGCCAGCACCCCGCGATGGAGCAGGGAGCCCTGGCCTGTCCG AAGACTGTTCTGAGTCTCAGCAAACGCCTGCAAGATCTTTGACCTTGCAAGAAGCACTGGAAGTTCGTAAGCCTCAGTTCATTTCTCGCT CACAAGAACGGCTGAAGAAGCTTGAACACATGGTCCAGCAGAGGAAAGCCCAGCGGAAGGAGGACCTGAGGCAGAAGCAGAGCCTCCTTC CCATCCGCACCAGCAAGAAGCAGTTCACGATTCCCCATCCTCTGAGTGATAACTTGTTCAAACCCAAAGAACGGTGCATTTCAGAGAAGG AGATGCATATGCGATCTAAGAGAATCTATGATAACTTGCCGGAAGTTAAAAAGAAAAAAGAAGAACAAAGGAAAAGGGTGATCTTACAAA GTAACAGACTCCGTGCCGAAGTCTTCAAAAAGCAATTACTGGACCAGCTCCTTCAAAGGAATGCGGTCTAACCACAGGCTGCCCTGCTGA CCACACTACCTGGACCTGGGAGGACTTCGAATGCTGGATAAGCCATTAAACTTAGCATTATCTTCATCATGGGAAAACACTTATTTTACT TTCGATTTTTTTTTTCCATAAAGGAAAACATCACTTCCTGAATTACTGACCCAAGCCAAACAGAAACAATAACCCTCGAGAAAATAGGTC AACAATCTGTTGTGGGGAAACCACCTCCATGTAACCCACTGGATACAGTCCCCTTAATGTTTTTGCTTCTAAATTGTACCTTTTGCTTCT GATTTCTTCTCCCCTGCTGTTTCCTGCCCATCAGAGAGGCCTGATACAAGCAAGTTTGTTTACATCCCTGGGGAATCTTTTACATCAAAC TTTTGGGATCCAAATCCATCTCCTTTTAAATTTCAATCTCAGCACCTGCCAGTTATGCAAATGCCAAAATGTGGGTCATCATATAGTATA TTTGAAACCTTTCTGAACATGTACACCACCCAATGCTAGAGGCTGACTTGGAAACCGGTGGGTGCAATGCCCGAGGCTGTGGAACAATCA GCCCATCTCTTTGTGACCTGGAGCAGTCAGAGGGCCCTCAGTCACCCCGCCCCATTCCTCACCAGAGAAAAGAATCCATTTCTATGGAAG CTCTGACGTAACTTCAGTGTTTTCTACAATACTCCTCCTGCCCCGCCCCATTAAAACAGTTCTTTTGTTAAGAAATAGCCTAATGGTCCA ACTTTGCTGTCTGTTCTTCCAAATGTTTATAATACACATTATTTATAAATATGTCTGTTTGGGAAGCTAAGAACAAGCTAGTTTTTACAA >83766_83766_1_SMAD2-C10orf90_SMAD2_chr18_45394694_ENST00000356825_C10orf90_chr10_128202508_ENST00000284694_length(amino acids)=880AA_BP=188 MSSILPFTPPVVKRLLGWKKSAGGSGGAGGGEQNGQEEKWCEKAVKSLVKKLKKTGRLDELEKAITTQNCNTKCVTIPRSLDGRLQVSHR KGLPHVIYCRLWRWPDLHSHHELKAIENCEYAFNLKKDEVCVNPYHYQRVETPVLPPVLVPRHTEILTELPPLDDYTHSIPENTNFPAGI EPQSNYIPGLRDSYHSRRDQIALKNLQSDVTEAKSDFTKETLASQNTKMISSIVISQMIDENKSRENRASLPLPCAIAQSRAHHAKQSLA NRSGVNIHRAFALLPGRLGIPAPSDERGPEAELPPKEERPCGGPRRGFASITITARRVGPPARALVWGTAGDSLCPKCRAEDTLFQAPPA LANGAHPGRHQRSFACTEFSRNSSVVRLKVPEAHTGLCERRKYWVTHADDKETSFSPDTPLSGKSPLVFSSCVHLRVSQQCPDSIYYVDK SLSVPIEPPQIASPKMHRSVLSLNLNCSSHRLTADGVDGLVNREPISEALKQELLEGDQDLVGQRWNPGLQESHLKETPSLRRVHLGTGA CPWSGSFPLENTELANVGANQVTVRKGEKDHTTHCHASDHANQLSIHIPGWSYRAVHTKVFSGSSKRQQGEVCMTVSAPPVEQKPTRHFL PIGDSSPSDDCLSRDLSEPTERRHQSFLKPRILFPGFLCPLQDVCASLQEDNGVQIESKFPKGDYTCCDLVVKIKECKKSEDPTTPEPSP AAPSPAPRDGAGSPGLSEDCSESQQTPARSLTLQEALEVRKPQFISRSQERLKKLEHMVQQRKAQRKEDLRQKQSLLPIRTSKKQFTIPH -------------------------------------------------------------- >83766_83766_2_SMAD2-C10orf90_SMAD2_chr18_45394694_ENST00000356825_C10orf90_chr10_128202508_ENST00000454341_length(transcript)=3605nt_BP=963nt GCCGGGAGGCGGGGCGGGCCGTAGGCAAAGGGAGGTGGGGAGGCGGTGGCCGGCGACTCCCCGCGCCCCGCTCGCCCCCCGGCCCTTCCC GCGGTGCTCGGCCTCGTTCCTTTCCTCCTCCGCTCCCTCCGTCTTCCATACCCGCCCCGCGCGGCTTTCGGCCGGCGTGCCTCGCGCCCT AACGGGCGGCTGGAGGCGCCAATCAGCGGGCGGCAGGGTGCCAGCCCCGGGGCTGCGCCGGCGAATCGGCGGGGCCCGCGGCCCAGGGTG GCAGGCGGGTCTACCCGCGCGGCCGCGGCGGCGGAGAAGCAGCTCGCCAGCCAGCAGCCCGCCAGCCGCCGGGAGGTTCGATACAAGAGG CTGTTTTCCTAGCGTGGCTTGCTGCCTTTGGTAAGAACATGTCGTCCATCTTGCCATTCACGCCGCCAGTTGTGAAGAGACTGCTGGGAT GGAAGAAGTCAGCTGGTGGGTCTGGAGGAGCAGGCGGAGGAGAGCAGAATGGGCAGGAAGAAAAGTGGTGTGAGAAAGCAGTGAAAAGTC TGGTGAAGAAGCTAAAGAAAACAGGACGATTAGATGAGCTTGAGAAAGCCATCACCACTCAAAACTGTAATACTAAATGTGTTACCATAC CAAGGTCTCTTGATGGTCGTCTCCAGGTATCCCATCGAAAAGGATTGCCACATGTTATATATTGCCGATTATGGCGCTGGCCTGATCTTC ACAGTCATCATGAACTCAAGGCAATTGAAAACTGCGAATATGCTTTTAATCTTAAAAAGGATGAAGTATGTGTAAACCCTTACCACTATC AGAGAGTTGAGACACCAGTTTTGCCTCCAGTATTAGTGCCCCGACACACCGAGATCCTAACAGAACTTCCGCCTCTGGATGACTATACTC ACTCCATTCCAGAAAACACTAACTTCCCAGCAGGAATTGAGCCACAGAGTAATTATATTCCAGGATTACGGGACAGCTACCACAGTAGAA GAGATCAAATTGCCCTTAAAAATCTCCAGTCTGATGTCACAGAGGCAAAATCTGACTTCACCAAGGAGACCCTGGCATCACAAAACACAA AAATGATTTCATCCATAGTCATCTCCCAGATGATTGATGAGAATAAGTCAAGAGAAAACAGGGCCTCCTTGCCCCTACCGTGTGCCATTG CTCAGTCTCGTGCACATCACGCCAAGCAATCTCTGGCTAACCGCAGCGGAGTCAACATTCACAGAGCATTTGCGTTACTTCCGGGCAGAT TAGGAATCCCGGCACCGTCAGATGAGCGAGGACCTGAGGCAGAGCTGCCGCCCAAAGAGGAGAGACCCTGTGGGGGCCCCCGCAGAGGGT TTGCATCCATCACCATCACGGCCAGACGCGTGGGCCCCCCAGCCCGCGCCCTGGTGTGGGGGACTGCTGGGGACTCTCTGTGCCCCAAGT GCAGGGCTGAGGACACACTGTTCCAGGCGCCCCCGGCTCTGGCCAATGGCGCCCATCCAGGTCGGCATCAGAGATCTTTTGCCTGCACAG AGTTCTCCAGAAACAGCTCCGTGGTGCGGCTGAAGGTTCCCGAGGCCCACACTGGGTTGTGTGAGAGACGCAAGTACTGGGTCACCCATG CAGACGACAAAGAGACCAGTTTTTCTCCAGACACCCCACTGTCAGGAAAGAGCCCGCTGGTGTTCAGTTCCTGTGTCCACCTCAGGGTGT CTCAGCAGTGTCCAGATTCAATCTATTACGTAGACAAGTCTCTCTCCGTCCCCATTGAGCCACCTCAAATTGCCAGCCCCAAAATGCACA GATCCGTCCTGTCGCTCAACCTCAATTGTAGTTCCCACAGATTAACAGCAGATGGAGTAGATGGCCTAGTGAACAGAGAGCCAATAAGCG AAGCCCTGAAGCAGGAGCTCCTGGAGGGAGACCAGGACCTCGTAGGCCAGCGCTGGAACCCAGGTTTACAAGAAAGTCACTTGAAGGAAA CCCCATCGTTGAGGCGGGTGCATTTGGGGACCGGCGCTTGTCCTTGGAGTGGTTCTTTTCCATTGGAAAACACAGAATTGGCAAATGTGG GAGCTAACCAAGTCACTGTAAGAAAAGGGGAAAAGGACCATACAACTCATTGTCACGCCAGCGATCATGCCAACCAACTGTCCATTCACA TTCCTGGCTGGAGTTACAGGGCAGGAGATTACACATGCTGTGACTTGGTTGTAAAAATAAAGGAATGTAAGAAGAGTGAGGACCCCACCA CACCTGAGCCCTCCCCAGCAGCACCCTCGCCAGCACCCCGCGATGGAGCAGGGAGCCCTGGCCTGTCCGAAGACTGTTCTGAGTCTCAGC AAACGCCTGCAAGATCTTTGACCTTGCAAGAAGCACTGGAAGTTCGTAAGCCTCAGTTCATTTCTCGCTCACAAGAACGGCTGAAGAAGC TTGAACACATGGTCCAGCAGAGGAAAGCCCAGCGGAAGGAGGACCTGAGGCAGAAGCAGAGCCTCCTTCCCATCCGCACCAGCAAGAAGC AGTTCACGATTCCCCATCCTCTGAGTGATAACTTGTTCAAACCCAAAGAACGGTGCATTTCAGAGAAGGAGATGCATATGCGATCTAAGA GAATCTATGATAACTTGCCGGAAGTTAAAAAGAAAAAAGAAGAACAAAGGAAAAGGGTGATCTTACAAAGTAACAGACTCCGTGCCGAAG TCTTCAAAAAGCAATTACTGGACCAGCTCCTTCAAAGGAATGCGGTCTAACCACAGGCTGCCCTGCTGACCACACTACCTGGACCTGGGA GGACTTCGAATGCTGGATAAGCCATTAAACTTAGCATTATCTTCATCATGGGAAAACACTTATTTTACTTTCGATTTTTTTTTTCCATAA AGGAAAACATCACTTCCTGAATTACTGACCCAAGCCAAACAGAAACAATAACCCTCGAGAAAATAGGTCAACAATCTGTTGTGGGGAAAC CACCTCCATGTAACCCACTGGATACAGTCCCCTTAATGTTTTTGCTTCTAAATTGTACCTTTTGCTTCTGATTTCTTCTCCCCTGCTGTT TCCTGCCCATCAGAGAGGCCTGATACAAGCAAGTTTGTTTACATCCCTGGGGAATCTTTTACATCAAACTTTTGGGATCCAAATCCATCT CCTTTTAAATTTCAATCTCAGCACCTGCCAGTTATGCAAATGCCAAAATGTGGGTCATCATATAGTATATTTGAAACCTTTCTGAACATG TACACCACCCAATGCTAGAGGCTGACTTGGAAACCGGTGGGTGCAATGCCCGAGGCTGTGGAACAATCAGCCCATCTCTTTGTGACCTGG AGCAGTCAGAGGGCCCTCAGTCACCCCGCCCCATTCCTCACCAGAGAAAAGAATCCATTTCTATGGAAGCTCTGACGTAACTTCAGTGTT TTCTACAATACTCCTCCTGCCCCGCCCCATTAAAACAGTTCTTTTGTTAAGAAATAGCCTAATGGTCCAACTTTGCTGTCTGTTCTTCCA AATGTTTATAATACACATTATTTATAAATATGTCTGTTTGGGAAGCTAAGAACAAGCTAGTTTTTACAACACAAATGGAAATAAATGCAA >83766_83766_2_SMAD2-C10orf90_SMAD2_chr18_45394694_ENST00000356825_C10orf90_chr10_128202508_ENST00000454341_length(amino acids)=783AA_BP=188 MSSILPFTPPVVKRLLGWKKSAGGSGGAGGGEQNGQEEKWCEKAVKSLVKKLKKTGRLDELEKAITTQNCNTKCVTIPRSLDGRLQVSHR KGLPHVIYCRLWRWPDLHSHHELKAIENCEYAFNLKKDEVCVNPYHYQRVETPVLPPVLVPRHTEILTELPPLDDYTHSIPENTNFPAGI EPQSNYIPGLRDSYHSRRDQIALKNLQSDVTEAKSDFTKETLASQNTKMISSIVISQMIDENKSRENRASLPLPCAIAQSRAHHAKQSLA NRSGVNIHRAFALLPGRLGIPAPSDERGPEAELPPKEERPCGGPRRGFASITITARRVGPPARALVWGTAGDSLCPKCRAEDTLFQAPPA LANGAHPGRHQRSFACTEFSRNSSVVRLKVPEAHTGLCERRKYWVTHADDKETSFSPDTPLSGKSPLVFSSCVHLRVSQQCPDSIYYVDK SLSVPIEPPQIASPKMHRSVLSLNLNCSSHRLTADGVDGLVNREPISEALKQELLEGDQDLVGQRWNPGLQESHLKETPSLRRVHLGTGA CPWSGSFPLENTELANVGANQVTVRKGEKDHTTHCHASDHANQLSIHIPGWSYRAGDYTCCDLVVKIKECKKSEDPTTPEPSPAAPSPAP RDGAGSPGLSEDCSESQQTPARSLTLQEALEVRKPQFISRSQERLKKLEHMVQQRKAQRKEDLRQKQSLLPIRTSKKQFTIPHPLSDNLF -------------------------------------------------------------- >83766_83766_3_SMAD2-C10orf90_SMAD2_chr18_45394694_ENST00000356825_C10orf90_chr10_128202508_ENST00000544758_length(transcript)=3340nt_BP=963nt GCCGGGAGGCGGGGCGGGCCGTAGGCAAAGGGAGGTGGGGAGGCGGTGGCCGGCGACTCCCCGCGCCCCGCTCGCCCCCCGGCCCTTCCC GCGGTGCTCGGCCTCGTTCCTTTCCTCCTCCGCTCCCTCCGTCTTCCATACCCGCCCCGCGCGGCTTTCGGCCGGCGTGCCTCGCGCCCT AACGGGCGGCTGGAGGCGCCAATCAGCGGGCGGCAGGGTGCCAGCCCCGGGGCTGCGCCGGCGAATCGGCGGGGCCCGCGGCCCAGGGTG GCAGGCGGGTCTACCCGCGCGGCCGCGGCGGCGGAGAAGCAGCTCGCCAGCCAGCAGCCCGCCAGCCGCCGGGAGGTTCGATACAAGAGG CTGTTTTCCTAGCGTGGCTTGCTGCCTTTGGTAAGAACATGTCGTCCATCTTGCCATTCACGCCGCCAGTTGTGAAGAGACTGCTGGGAT GGAAGAAGTCAGCTGGTGGGTCTGGAGGAGCAGGCGGAGGAGAGCAGAATGGGCAGGAAGAAAAGTGGTGTGAGAAAGCAGTGAAAAGTC TGGTGAAGAAGCTAAAGAAAACAGGACGATTAGATGAGCTTGAGAAAGCCATCACCACTCAAAACTGTAATACTAAATGTGTTACCATAC CAAGGTCTCTTGATGGTCGTCTCCAGGTATCCCATCGAAAAGGATTGCCACATGTTATATATTGCCGATTATGGCGCTGGCCTGATCTTC ACAGTCATCATGAACTCAAGGCAATTGAAAACTGCGAATATGCTTTTAATCTTAAAAAGGATGAAGTATGTGTAAACCCTTACCACTATC AGAGAGTTGAGACACCAGTTTTGCCTCCAGTATTAGTGCCCCGACACACCGAGATCCTAACAGAACTTCCGCCTCTGGATGACTATACTC ACTCCATTCCAGAAAACACTAACTTCCCAGCAGGAATTGAGCCACAGAGTAATTATATTCCAGGATTACGGGACAGCTACCACAGTAGAA GAGATCAAATTGCCCTTAAAAATCTCCAGTCTGATGTCACAGAGGCAAAATCTGACTTCACCAAGGAGACCCTGGCATCACAAAACACAA AAATGATTTCATCCATAGTCATCTCCCAGATGATTGATGAGAATAAGTCAAGAGAAAACAGGGCCTCCTTGCCCCTACCGTGTGCCATTG CTCAGTCTCGTGCACATCACGCCAAGCAATCTCTGGCTAACCGCAGCGGAGTCAACATTCACAGAGCATTTGCGTTACTTCCGGGCAGAT TAGGAATCCCGGCACCGTCAGATGAGCGAGGACCTGAGGCAGAGCTGCCGCCCAAAGAGGAGAGACCCTGTGGGGGCCCCCGCAGAGGGT TTGCATCCATCACCATCACGGCCAGACGCGTGGGCCCCCCAGCCCGCGCCCTGGTGTGGGGGACTGCTGGGGACTCTCTGTGCCCCAAGT GCAGGGCTGAGGACACACTGTTCCAGGCGCCCCCGGCTCTGGCCAATGGCGCCCATCCAGGTCGGCATCAGAGATCTTTTGCCTGCACAG AGTTCTCCAGAAACAGCTCCGTGGTGCGGCTGAAGGTTCCCGAGGCCCACACTGGGTTGTGTGAGAGACGCAAGTACTGGGTCACCCATG CAGACGACAAAGAGACCAGTTTTTCTCCAGACACCCCACTGTCAGGAAAGAGCCCGCTGGTGTTCAGTTCCTGTGTCCACCTCAGGGTGT CTCAGCAGTGTCCAGATTCAATCTATTACGTAGACAAGTCTCTCTCCGTCCCCATTGAGCCACCTCAAATTGCCAGCCCCAAAATGCACA GATCCGTCCTGTCGCTCAACCTCAATTGTAGTTCCCACAGATTAACAGCAGATGGAGTAGATGGCCTAGTGAACAGAGAGCCAATAAGCG AAGCCCTGAAGCAGGAGCTCCTGGAGGGAGACCAGGACCTCGTAGGCCAGCGCTGGAACCCAGGTTTACAAGAAAGTCACTTGAAGGAAA CCCCATCGTTGAGGCGGGTGCATTTGGGGACCGGCGCTTGTCCTTGGAGTGGTTCTTTTCCATTGGAAAACACAGAATTGGCAAATGTGG GAGCTAACCAAGTCACTGTAAGAAAAGGGGAAAAGGACCATACAACTCATTGTCACGCCAGCGATCATGCCAACCAACTGTCCATTCACA TTCCTGGCTGGAGTTACAGGGCAGTACACACAAAAGTATTTTCTGGAAGCAGCAAGAGGCAACAAGGAGAAGTATGTATGACTGTGTCTG CTCCTCCAGTGGAACAGAAGCCCACTAGACATTTCCTTCCCATTGGGGATAGCTCTCCAAGCGATGACTGTCTGTCTAGAGACCTTTCTG AGCCCACAGAGAGACGACATCAAAGCTTCCTGAAACCCAGAATCCTTTTTCCTGGGTTTCTTTGCCCCTTACAAGATGTATGTGCATCTC TGCAGGAAGACAATGGTGTTCAGATAGAAAGCAAGTTCCCCAAAGGAGATTACACATGCTGTGACTTGGTTGTAAAAATAAAGGAATGTA AGAAGAGTGAGGACCCCACCACACCTGAGCCCTCCCCAGCAGCACCCTCGCCAGCACCCCGCGATGGAGCAGGGAGCCCTGGCCTGTCCG AAGACTGTTCTGAGTCTCAGCAAACGCCTGCAAGATCTTTGACCTTGCAAGAAGCACTGGAAGTTCGTAAGCCTCAGTTCATTTCTCGCT CACAAGAACGGCTGAAGAAGCTTGAACACATGGTCCAGCAGAGGAAAGCCCAGCGGAAGGAGGACCTGAGGCAGAAGCAGAGCCTCCTTC CCATCCGCACCAGCAAGAAGCAGTTCACGATTCCCCATCCTCTGAGTGATAACTTGTTCAAACCCAAAGAACGGTGCATTTCAGAGAAGG AGATGCATATGCGATCTAAGAGAATCTATGATAACTTGCCGGAAGTTAAAAAGAAAAAAGAAGAACAAAGGAAAAGGGTGATCTTACAAA GTAACAGACTCCGTGCCGAAGTCTTCAAAAAGCAATTACTGGACCAGCTCCTTCAAAGGAATGCGGTCTAACCACAGGCTGCCCTGCTGA CCACACTACCTGGACCTGGGAGGACTTCGAATGCTGGATAAGCCATTAAACTTAGCATTATCTTCATCATGGGAAAACACTTATTTTACT TTCGATTTTTTTTTTCCATAAAGGAAAACATCACTTCCTGAATTACTGACCCAAGCCAAACAGAAACAATAACCCTCGAGAAAATAGGTC AACAATCTGTTGTGGGGAAACCACCTCCATGTAACCCACTGGATACAGTCCCCTTAATGTTTTTGCTTCTAAATTGTACCTTTTGCTTCT >83766_83766_3_SMAD2-C10orf90_SMAD2_chr18_45394694_ENST00000356825_C10orf90_chr10_128202508_ENST00000544758_length(amino acids)=880AA_BP=188 MSSILPFTPPVVKRLLGWKKSAGGSGGAGGGEQNGQEEKWCEKAVKSLVKKLKKTGRLDELEKAITTQNCNTKCVTIPRSLDGRLQVSHR KGLPHVIYCRLWRWPDLHSHHELKAIENCEYAFNLKKDEVCVNPYHYQRVETPVLPPVLVPRHTEILTELPPLDDYTHSIPENTNFPAGI EPQSNYIPGLRDSYHSRRDQIALKNLQSDVTEAKSDFTKETLASQNTKMISSIVISQMIDENKSRENRASLPLPCAIAQSRAHHAKQSLA NRSGVNIHRAFALLPGRLGIPAPSDERGPEAELPPKEERPCGGPRRGFASITITARRVGPPARALVWGTAGDSLCPKCRAEDTLFQAPPA LANGAHPGRHQRSFACTEFSRNSSVVRLKVPEAHTGLCERRKYWVTHADDKETSFSPDTPLSGKSPLVFSSCVHLRVSQQCPDSIYYVDK SLSVPIEPPQIASPKMHRSVLSLNLNCSSHRLTADGVDGLVNREPISEALKQELLEGDQDLVGQRWNPGLQESHLKETPSLRRVHLGTGA CPWSGSFPLENTELANVGANQVTVRKGEKDHTTHCHASDHANQLSIHIPGWSYRAVHTKVFSGSSKRQQGEVCMTVSAPPVEQKPTRHFL PIGDSSPSDDCLSRDLSEPTERRHQSFLKPRILFPGFLCPLQDVCASLQEDNGVQIESKFPKGDYTCCDLVVKIKECKKSEDPTTPEPSP AAPSPAPRDGAGSPGLSEDCSESQQTPARSLTLQEALEVRKPQFISRSQERLKKLEHMVQQRKAQRKEDLRQKQSLLPIRTSKKQFTIPH -------------------------------------------------------------- >83766_83766_4_SMAD2-C10orf90_SMAD2_chr18_45394694_ENST00000402690_C10orf90_chr10_128202508_ENST00000284694_length(transcript)=3983nt_BP=1050nt GGGAGGCGGGGCGGGCCGTAGGCAAAGGGAGGTGGGGAGGCGGTGGCCGGCGACTCCCCGCGCCCCGCTCGCCCCCCGGCCCTTCCCGCG GTGCTCGGCCTCGTTCCTTTCCTCCTCCGCTCCCTCCGTCTTCCATACCCGCCCCGCGCGGCTTTCGGCCGGCGTGCCTCGCGCCCTAAC GGGCGGCTGGAGGCGCCAATCAGCGGGCGGCAGGGTGCCAGCCCCGGGGCTGCGCCGGCGAATCGGCGGGGCCCGCGGCCCAGGGTGGCA GGCGGGTCTACCCGCGCGGCCGCGGCGGCGGAGAAGCAGCTCGCCAGCCAGCAGCCCGCCAGCCGCCGGGAGGTTCGATACAAGAGGCTG TTTTCCTAGCGTGGCTTGCTGCCTTTGGTAAGAACATGTCGTCCATCTTGCCATTCACGCCGCCAGTTGTGAAGAGACTGCTGGGATGGA AGAAGTCAGCTGGTGGGTCTGGAGGAGCAGGCGGAGGAGAGCAGAATGGGCAGGAAGAAAAGTGGTGTGAGAAAGCAGTGAAAAGTCTGG TGAAGAAGCTAAAGAAAACAGGACGATTAGATGAGCTTGAGAAAGCCATCACCACTCAAAACTGTAATACTAAATGTGTTACCATACCAA GCACTTGCTCTGAAATTTGGGGACTGAGTACACCAAATACGATAGATCAGTGGGATACAACAGGCCTTTACAGCTTCTCTGAACAAACCA GGTCTCTTGATGGTCGTCTCCAGGTATCCCATCGAAAAGGATTGCCACATGTTATATATTGCCGATTATGGCGCTGGCCTGATCTTCACA GTCATCATGAACTCAAGGCAATTGAAAACTGCGAATATGCTTTTAATCTTAAAAAGGATGAAGTATGTGTAAACCCTTACCACTATCAGA GAGTTGAGACACCAGTTTTGCCTCCAGTATTAGTGCCCCGACACACCGAGATCCTAACAGAACTTCCGCCTCTGGATGACTATACTCACT CCATTCCAGAAAACACTAACTTCCCAGCAGGAATTGAGCCACAGAGTAATTATATTCCAGGATTACGGGACAGCTACCACAGTAGAAGAG ATCAAATTGCCCTTAAAAATCTCCAGTCTGATGTCACAGAGGCAAAATCTGACTTCACCAAGGAGACCCTGGCATCACAAAACACAAAAA TGATTTCATCCATAGTCATCTCCCAGATGATTGATGAGAATAAGTCAAGAGAAAACAGGGCCTCCTTGCCCCTACCGTGTGCCATTGCTC AGTCTCGTGCACATCACGCCAAGCAATCTCTGGCTAACCGCAGCGGAGTCAACATTCACAGAGCATTTGCGTTACTTCCGGGCAGATTAG GAATCCCGGCACCGTCAGATGAGCGAGGACCTGAGGCAGAGCTGCCGCCCAAAGAGGAGAGACCCTGTGGGGGCCCCCGCAGAGGGTTTG CATCCATCACCATCACGGCCAGACGCGTGGGCCCCCCAGCCCGCGCCCTGGTGTGGGGGACTGCTGGGGACTCTCTGTGCCCCAAGTGCA GGGCTGAGGACACACTGTTCCAGGCGCCCCCGGCTCTGGCCAATGGCGCCCATCCAGGTCGGCATCAGAGATCTTTTGCCTGCACAGAGT TCTCCAGAAACAGCTCCGTGGTGCGGCTGAAGGTTCCCGAGGCCCACACTGGGTTGTGTGAGAGACGCAAGTACTGGGTCACCCATGCAG ACGACAAAGAGACCAGTTTTTCTCCAGACACCCCACTGTCAGGAAAGAGCCCGCTGGTGTTCAGTTCCTGTGTCCACCTCAGGGTGTCTC AGCAGTGTCCAGATTCAATCTATTACGTAGACAAGTCTCTCTCCGTCCCCATTGAGCCACCTCAAATTGCCAGCCCCAAAATGCACAGAT CCGTCCTGTCGCTCAACCTCAATTGTAGTTCCCACAGATTAACAGCAGATGGAGTAGATGGCCTAGTGAACAGAGAGCCAATAAGCGAAG CCCTGAAGCAGGAGCTCCTGGAGGGAGACCAGGACCTCGTAGGCCAGCGCTGGAACCCAGGTTTACAAGAAAGTCACTTGAAGGAAACCC CATCGTTGAGGCGGGTGCATTTGGGGACCGGCGCTTGTCCTTGGAGTGGTTCTTTTCCATTGGAAAACACAGAATTGGCAAATGTGGGAG CTAACCAAGTCACTGTAAGAAAAGGGGAAAAGGACCATACAACTCATTGTCACGCCAGCGATCATGCCAACCAACTGTCCATTCACATTC CTGGCTGGAGTTACAGGGCAGTACACACAAAAGTATTTTCTGGAAGCAGCAAGAGGCAACAAGGAGAAGTATGTATGACTGTGTCTGCTC CTCCAGTGGAACAGAAGCCCACTAGACATTTCCTTCCCATTGGGGATAGCTCTCCAAGCGATGACTGTCTGTCTAGAGACCTTTCTGAGC CCACAGAGAGACGACATCAAAGCTTCCTGAAACCCAGAATCCTTTTTCCTGGGTTTCTTTGCCCCTTACAAGATGTATGTGCATCTCTGC AGGAAGACAATGGTGTTCAGATAGAAAGCAAGTTCCCCAAAGGAGATTACACATGCTGTGACTTGGTTGTAAAAATAAAGGAATGTAAGA AGAGTGAGGACCCCACCACACCTGAGCCCTCCCCAGCAGCACCCTCGCCAGCACCCCGCGATGGAGCAGGGAGCCCTGGCCTGTCCGAAG ACTGTTCTGAGTCTCAGCAAACGCCTGCAAGATCTTTGACCTTGCAAGAAGCACTGGAAGTTCGTAAGCCTCAGTTCATTTCTCGCTCAC AAGAACGGCTGAAGAAGCTTGAACACATGGTCCAGCAGAGGAAAGCCCAGCGGAAGGAGGACCTGAGGCAGAAGCAGAGCCTCCTTCCCA TCCGCACCAGCAAGAAGCAGTTCACGATTCCCCATCCTCTGAGTGATAACTTGTTCAAACCCAAAGAACGGTGCATTTCAGAGAAGGAGA TGCATATGCGATCTAAGAGAATCTATGATAACTTGCCGGAAGTTAAAAAGAAAAAAGAAGAACAAAGGAAAAGGGTGATCTTACAAAGTA ACAGACTCCGTGCCGAAGTCTTCAAAAAGCAATTACTGGACCAGCTCCTTCAAAGGAATGCGGTCTAACCACAGGCTGCCCTGCTGACCA CACTACCTGGACCTGGGAGGACTTCGAATGCTGGATAAGCCATTAAACTTAGCATTATCTTCATCATGGGAAAACACTTATTTTACTTTC GATTTTTTTTTTCCATAAAGGAAAACATCACTTCCTGAATTACTGACCCAAGCCAAACAGAAACAATAACCCTCGAGAAAATAGGTCAAC AATCTGTTGTGGGGAAACCACCTCCATGTAACCCACTGGATACAGTCCCCTTAATGTTTTTGCTTCTAAATTGTACCTTTTGCTTCTGAT TTCTTCTCCCCTGCTGTTTCCTGCCCATCAGAGAGGCCTGATACAAGCAAGTTTGTTTACATCCCTGGGGAATCTTTTACATCAAACTTT TGGGATCCAAATCCATCTCCTTTTAAATTTCAATCTCAGCACCTGCCAGTTATGCAAATGCCAAAATGTGGGTCATCATATAGTATATTT GAAACCTTTCTGAACATGTACACCACCCAATGCTAGAGGCTGACTTGGAAACCGGTGGGTGCAATGCCCGAGGCTGTGGAACAATCAGCC CATCTCTTTGTGACCTGGAGCAGTCAGAGGGCCCTCAGTCACCCCGCCCCATTCCTCACCAGAGAAAAGAATCCATTTCTATGGAAGCTC TGACGTAACTTCAGTGTTTTCTACAATACTCCTCCTGCCCCGCCCCATTAAAACAGTTCTTTTGTTAAGAAATAGCCTAATGGTCCAACT TTGCTGTCTGTTCTTCCAAATGTTTATAATACACATTATTTATAAATATGTCTGTTTGGGAAGCTAAGAACAAGCTAGTTTTTACAACAC >83766_83766_4_SMAD2-C10orf90_SMAD2_chr18_45394694_ENST00000402690_C10orf90_chr10_128202508_ENST00000284694_length(amino acids)=910AA_BP=218 MSSILPFTPPVVKRLLGWKKSAGGSGGAGGGEQNGQEEKWCEKAVKSLVKKLKKTGRLDELEKAITTQNCNTKCVTIPSTCSEIWGLSTP NTIDQWDTTGLYSFSEQTRSLDGRLQVSHRKGLPHVIYCRLWRWPDLHSHHELKAIENCEYAFNLKKDEVCVNPYHYQRVETPVLPPVLV PRHTEILTELPPLDDYTHSIPENTNFPAGIEPQSNYIPGLRDSYHSRRDQIALKNLQSDVTEAKSDFTKETLASQNTKMISSIVISQMID ENKSRENRASLPLPCAIAQSRAHHAKQSLANRSGVNIHRAFALLPGRLGIPAPSDERGPEAELPPKEERPCGGPRRGFASITITARRVGP PARALVWGTAGDSLCPKCRAEDTLFQAPPALANGAHPGRHQRSFACTEFSRNSSVVRLKVPEAHTGLCERRKYWVTHADDKETSFSPDTP LSGKSPLVFSSCVHLRVSQQCPDSIYYVDKSLSVPIEPPQIASPKMHRSVLSLNLNCSSHRLTADGVDGLVNREPISEALKQELLEGDQD LVGQRWNPGLQESHLKETPSLRRVHLGTGACPWSGSFPLENTELANVGANQVTVRKGEKDHTTHCHASDHANQLSIHIPGWSYRAVHTKV FSGSSKRQQGEVCMTVSAPPVEQKPTRHFLPIGDSSPSDDCLSRDLSEPTERRHQSFLKPRILFPGFLCPLQDVCASLQEDNGVQIESKF PKGDYTCCDLVVKIKECKKSEDPTTPEPSPAAPSPAPRDGAGSPGLSEDCSESQQTPARSLTLQEALEVRKPQFISRSQERLKKLEHMVQ QRKAQRKEDLRQKQSLLPIRTSKKQFTIPHPLSDNLFKPKERCISEKEMHMRSKRIYDNLPEVKKKKEEQRKRVILQSNRLRAEVFKKQL -------------------------------------------------------------- >83766_83766_5_SMAD2-C10orf90_SMAD2_chr18_45394694_ENST00000402690_C10orf90_chr10_128202508_ENST00000454341_length(transcript)=3692nt_BP=1050nt GGGAGGCGGGGCGGGCCGTAGGCAAAGGGAGGTGGGGAGGCGGTGGCCGGCGACTCCCCGCGCCCCGCTCGCCCCCCGGCCCTTCCCGCG GTGCTCGGCCTCGTTCCTTTCCTCCTCCGCTCCCTCCGTCTTCCATACCCGCCCCGCGCGGCTTTCGGCCGGCGTGCCTCGCGCCCTAAC GGGCGGCTGGAGGCGCCAATCAGCGGGCGGCAGGGTGCCAGCCCCGGGGCTGCGCCGGCGAATCGGCGGGGCCCGCGGCCCAGGGTGGCA GGCGGGTCTACCCGCGCGGCCGCGGCGGCGGAGAAGCAGCTCGCCAGCCAGCAGCCCGCCAGCCGCCGGGAGGTTCGATACAAGAGGCTG TTTTCCTAGCGTGGCTTGCTGCCTTTGGTAAGAACATGTCGTCCATCTTGCCATTCACGCCGCCAGTTGTGAAGAGACTGCTGGGATGGA AGAAGTCAGCTGGTGGGTCTGGAGGAGCAGGCGGAGGAGAGCAGAATGGGCAGGAAGAAAAGTGGTGTGAGAAAGCAGTGAAAAGTCTGG TGAAGAAGCTAAAGAAAACAGGACGATTAGATGAGCTTGAGAAAGCCATCACCACTCAAAACTGTAATACTAAATGTGTTACCATACCAA GCACTTGCTCTGAAATTTGGGGACTGAGTACACCAAATACGATAGATCAGTGGGATACAACAGGCCTTTACAGCTTCTCTGAACAAACCA GGTCTCTTGATGGTCGTCTCCAGGTATCCCATCGAAAAGGATTGCCACATGTTATATATTGCCGATTATGGCGCTGGCCTGATCTTCACA GTCATCATGAACTCAAGGCAATTGAAAACTGCGAATATGCTTTTAATCTTAAAAAGGATGAAGTATGTGTAAACCCTTACCACTATCAGA GAGTTGAGACACCAGTTTTGCCTCCAGTATTAGTGCCCCGACACACCGAGATCCTAACAGAACTTCCGCCTCTGGATGACTATACTCACT CCATTCCAGAAAACACTAACTTCCCAGCAGGAATTGAGCCACAGAGTAATTATATTCCAGGATTACGGGACAGCTACCACAGTAGAAGAG ATCAAATTGCCCTTAAAAATCTCCAGTCTGATGTCACAGAGGCAAAATCTGACTTCACCAAGGAGACCCTGGCATCACAAAACACAAAAA TGATTTCATCCATAGTCATCTCCCAGATGATTGATGAGAATAAGTCAAGAGAAAACAGGGCCTCCTTGCCCCTACCGTGTGCCATTGCTC AGTCTCGTGCACATCACGCCAAGCAATCTCTGGCTAACCGCAGCGGAGTCAACATTCACAGAGCATTTGCGTTACTTCCGGGCAGATTAG GAATCCCGGCACCGTCAGATGAGCGAGGACCTGAGGCAGAGCTGCCGCCCAAAGAGGAGAGACCCTGTGGGGGCCCCCGCAGAGGGTTTG CATCCATCACCATCACGGCCAGACGCGTGGGCCCCCCAGCCCGCGCCCTGGTGTGGGGGACTGCTGGGGACTCTCTGTGCCCCAAGTGCA GGGCTGAGGACACACTGTTCCAGGCGCCCCCGGCTCTGGCCAATGGCGCCCATCCAGGTCGGCATCAGAGATCTTTTGCCTGCACAGAGT TCTCCAGAAACAGCTCCGTGGTGCGGCTGAAGGTTCCCGAGGCCCACACTGGGTTGTGTGAGAGACGCAAGTACTGGGTCACCCATGCAG ACGACAAAGAGACCAGTTTTTCTCCAGACACCCCACTGTCAGGAAAGAGCCCGCTGGTGTTCAGTTCCTGTGTCCACCTCAGGGTGTCTC AGCAGTGTCCAGATTCAATCTATTACGTAGACAAGTCTCTCTCCGTCCCCATTGAGCCACCTCAAATTGCCAGCCCCAAAATGCACAGAT CCGTCCTGTCGCTCAACCTCAATTGTAGTTCCCACAGATTAACAGCAGATGGAGTAGATGGCCTAGTGAACAGAGAGCCAATAAGCGAAG CCCTGAAGCAGGAGCTCCTGGAGGGAGACCAGGACCTCGTAGGCCAGCGCTGGAACCCAGGTTTACAAGAAAGTCACTTGAAGGAAACCC CATCGTTGAGGCGGGTGCATTTGGGGACCGGCGCTTGTCCTTGGAGTGGTTCTTTTCCATTGGAAAACACAGAATTGGCAAATGTGGGAG CTAACCAAGTCACTGTAAGAAAAGGGGAAAAGGACCATACAACTCATTGTCACGCCAGCGATCATGCCAACCAACTGTCCATTCACATTC CTGGCTGGAGTTACAGGGCAGGAGATTACACATGCTGTGACTTGGTTGTAAAAATAAAGGAATGTAAGAAGAGTGAGGACCCCACCACAC CTGAGCCCTCCCCAGCAGCACCCTCGCCAGCACCCCGCGATGGAGCAGGGAGCCCTGGCCTGTCCGAAGACTGTTCTGAGTCTCAGCAAA CGCCTGCAAGATCTTTGACCTTGCAAGAAGCACTGGAAGTTCGTAAGCCTCAGTTCATTTCTCGCTCACAAGAACGGCTGAAGAAGCTTG AACACATGGTCCAGCAGAGGAAAGCCCAGCGGAAGGAGGACCTGAGGCAGAAGCAGAGCCTCCTTCCCATCCGCACCAGCAAGAAGCAGT TCACGATTCCCCATCCTCTGAGTGATAACTTGTTCAAACCCAAAGAACGGTGCATTTCAGAGAAGGAGATGCATATGCGATCTAAGAGAA TCTATGATAACTTGCCGGAAGTTAAAAAGAAAAAAGAAGAACAAAGGAAAAGGGTGATCTTACAAAGTAACAGACTCCGTGCCGAAGTCT TCAAAAAGCAATTACTGGACCAGCTCCTTCAAAGGAATGCGGTCTAACCACAGGCTGCCCTGCTGACCACACTACCTGGACCTGGGAGGA CTTCGAATGCTGGATAAGCCATTAAACTTAGCATTATCTTCATCATGGGAAAACACTTATTTTACTTTCGATTTTTTTTTTCCATAAAGG AAAACATCACTTCCTGAATTACTGACCCAAGCCAAACAGAAACAATAACCCTCGAGAAAATAGGTCAACAATCTGTTGTGGGGAAACCAC CTCCATGTAACCCACTGGATACAGTCCCCTTAATGTTTTTGCTTCTAAATTGTACCTTTTGCTTCTGATTTCTTCTCCCCTGCTGTTTCC TGCCCATCAGAGAGGCCTGATACAAGCAAGTTTGTTTACATCCCTGGGGAATCTTTTACATCAAACTTTTGGGATCCAAATCCATCTCCT TTTAAATTTCAATCTCAGCACCTGCCAGTTATGCAAATGCCAAAATGTGGGTCATCATATAGTATATTTGAAACCTTTCTGAACATGTAC ACCACCCAATGCTAGAGGCTGACTTGGAAACCGGTGGGTGCAATGCCCGAGGCTGTGGAACAATCAGCCCATCTCTTTGTGACCTGGAGC AGTCAGAGGGCCCTCAGTCACCCCGCCCCATTCCTCACCAGAGAAAAGAATCCATTTCTATGGAAGCTCTGACGTAACTTCAGTGTTTTC TACAATACTCCTCCTGCCCCGCCCCATTAAAACAGTTCTTTTGTTAAGAAATAGCCTAATGGTCCAACTTTGCTGTCTGTTCTTCCAAAT GTTTATAATACACATTATTTATAAATATGTCTGTTTGGGAAGCTAAGAACAAGCTAGTTTTTACAACACAAATGGAAATAAATGCAATTA >83766_83766_5_SMAD2-C10orf90_SMAD2_chr18_45394694_ENST00000402690_C10orf90_chr10_128202508_ENST00000454341_length(amino acids)=813AA_BP=218 MSSILPFTPPVVKRLLGWKKSAGGSGGAGGGEQNGQEEKWCEKAVKSLVKKLKKTGRLDELEKAITTQNCNTKCVTIPSTCSEIWGLSTP NTIDQWDTTGLYSFSEQTRSLDGRLQVSHRKGLPHVIYCRLWRWPDLHSHHELKAIENCEYAFNLKKDEVCVNPYHYQRVETPVLPPVLV PRHTEILTELPPLDDYTHSIPENTNFPAGIEPQSNYIPGLRDSYHSRRDQIALKNLQSDVTEAKSDFTKETLASQNTKMISSIVISQMID ENKSRENRASLPLPCAIAQSRAHHAKQSLANRSGVNIHRAFALLPGRLGIPAPSDERGPEAELPPKEERPCGGPRRGFASITITARRVGP PARALVWGTAGDSLCPKCRAEDTLFQAPPALANGAHPGRHQRSFACTEFSRNSSVVRLKVPEAHTGLCERRKYWVTHADDKETSFSPDTP LSGKSPLVFSSCVHLRVSQQCPDSIYYVDKSLSVPIEPPQIASPKMHRSVLSLNLNCSSHRLTADGVDGLVNREPISEALKQELLEGDQD LVGQRWNPGLQESHLKETPSLRRVHLGTGACPWSGSFPLENTELANVGANQVTVRKGEKDHTTHCHASDHANQLSIHIPGWSYRAGDYTC CDLVVKIKECKKSEDPTTPEPSPAAPSPAPRDGAGSPGLSEDCSESQQTPARSLTLQEALEVRKPQFISRSQERLKKLEHMVQQRKAQRK EDLRQKQSLLPIRTSKKQFTIPHPLSDNLFKPKERCISEKEMHMRSKRIYDNLPEVKKKKEEQRKRVILQSNRLRAEVFKKQLLDQLLQR -------------------------------------------------------------- >83766_83766_6_SMAD2-C10orf90_SMAD2_chr18_45394694_ENST00000402690_C10orf90_chr10_128202508_ENST00000544758_length(transcript)=3427nt_BP=1050nt GGGAGGCGGGGCGGGCCGTAGGCAAAGGGAGGTGGGGAGGCGGTGGCCGGCGACTCCCCGCGCCCCGCTCGCCCCCCGGCCCTTCCCGCG GTGCTCGGCCTCGTTCCTTTCCTCCTCCGCTCCCTCCGTCTTCCATACCCGCCCCGCGCGGCTTTCGGCCGGCGTGCCTCGCGCCCTAAC GGGCGGCTGGAGGCGCCAATCAGCGGGCGGCAGGGTGCCAGCCCCGGGGCTGCGCCGGCGAATCGGCGGGGCCCGCGGCCCAGGGTGGCA GGCGGGTCTACCCGCGCGGCCGCGGCGGCGGAGAAGCAGCTCGCCAGCCAGCAGCCCGCCAGCCGCCGGGAGGTTCGATACAAGAGGCTG TTTTCCTAGCGTGGCTTGCTGCCTTTGGTAAGAACATGTCGTCCATCTTGCCATTCACGCCGCCAGTTGTGAAGAGACTGCTGGGATGGA AGAAGTCAGCTGGTGGGTCTGGAGGAGCAGGCGGAGGAGAGCAGAATGGGCAGGAAGAAAAGTGGTGTGAGAAAGCAGTGAAAAGTCTGG TGAAGAAGCTAAAGAAAACAGGACGATTAGATGAGCTTGAGAAAGCCATCACCACTCAAAACTGTAATACTAAATGTGTTACCATACCAA GCACTTGCTCTGAAATTTGGGGACTGAGTACACCAAATACGATAGATCAGTGGGATACAACAGGCCTTTACAGCTTCTCTGAACAAACCA GGTCTCTTGATGGTCGTCTCCAGGTATCCCATCGAAAAGGATTGCCACATGTTATATATTGCCGATTATGGCGCTGGCCTGATCTTCACA GTCATCATGAACTCAAGGCAATTGAAAACTGCGAATATGCTTTTAATCTTAAAAAGGATGAAGTATGTGTAAACCCTTACCACTATCAGA GAGTTGAGACACCAGTTTTGCCTCCAGTATTAGTGCCCCGACACACCGAGATCCTAACAGAACTTCCGCCTCTGGATGACTATACTCACT CCATTCCAGAAAACACTAACTTCCCAGCAGGAATTGAGCCACAGAGTAATTATATTCCAGGATTACGGGACAGCTACCACAGTAGAAGAG ATCAAATTGCCCTTAAAAATCTCCAGTCTGATGTCACAGAGGCAAAATCTGACTTCACCAAGGAGACCCTGGCATCACAAAACACAAAAA TGATTTCATCCATAGTCATCTCCCAGATGATTGATGAGAATAAGTCAAGAGAAAACAGGGCCTCCTTGCCCCTACCGTGTGCCATTGCTC AGTCTCGTGCACATCACGCCAAGCAATCTCTGGCTAACCGCAGCGGAGTCAACATTCACAGAGCATTTGCGTTACTTCCGGGCAGATTAG GAATCCCGGCACCGTCAGATGAGCGAGGACCTGAGGCAGAGCTGCCGCCCAAAGAGGAGAGACCCTGTGGGGGCCCCCGCAGAGGGTTTG CATCCATCACCATCACGGCCAGACGCGTGGGCCCCCCAGCCCGCGCCCTGGTGTGGGGGACTGCTGGGGACTCTCTGTGCCCCAAGTGCA GGGCTGAGGACACACTGTTCCAGGCGCCCCCGGCTCTGGCCAATGGCGCCCATCCAGGTCGGCATCAGAGATCTTTTGCCTGCACAGAGT TCTCCAGAAACAGCTCCGTGGTGCGGCTGAAGGTTCCCGAGGCCCACACTGGGTTGTGTGAGAGACGCAAGTACTGGGTCACCCATGCAG ACGACAAAGAGACCAGTTTTTCTCCAGACACCCCACTGTCAGGAAAGAGCCCGCTGGTGTTCAGTTCCTGTGTCCACCTCAGGGTGTCTC AGCAGTGTCCAGATTCAATCTATTACGTAGACAAGTCTCTCTCCGTCCCCATTGAGCCACCTCAAATTGCCAGCCCCAAAATGCACAGAT CCGTCCTGTCGCTCAACCTCAATTGTAGTTCCCACAGATTAACAGCAGATGGAGTAGATGGCCTAGTGAACAGAGAGCCAATAAGCGAAG CCCTGAAGCAGGAGCTCCTGGAGGGAGACCAGGACCTCGTAGGCCAGCGCTGGAACCCAGGTTTACAAGAAAGTCACTTGAAGGAAACCC CATCGTTGAGGCGGGTGCATTTGGGGACCGGCGCTTGTCCTTGGAGTGGTTCTTTTCCATTGGAAAACACAGAATTGGCAAATGTGGGAG CTAACCAAGTCACTGTAAGAAAAGGGGAAAAGGACCATACAACTCATTGTCACGCCAGCGATCATGCCAACCAACTGTCCATTCACATTC CTGGCTGGAGTTACAGGGCAGTACACACAAAAGTATTTTCTGGAAGCAGCAAGAGGCAACAAGGAGAAGTATGTATGACTGTGTCTGCTC CTCCAGTGGAACAGAAGCCCACTAGACATTTCCTTCCCATTGGGGATAGCTCTCCAAGCGATGACTGTCTGTCTAGAGACCTTTCTGAGC CCACAGAGAGACGACATCAAAGCTTCCTGAAACCCAGAATCCTTTTTCCTGGGTTTCTTTGCCCCTTACAAGATGTATGTGCATCTCTGC AGGAAGACAATGGTGTTCAGATAGAAAGCAAGTTCCCCAAAGGAGATTACACATGCTGTGACTTGGTTGTAAAAATAAAGGAATGTAAGA AGAGTGAGGACCCCACCACACCTGAGCCCTCCCCAGCAGCACCCTCGCCAGCACCCCGCGATGGAGCAGGGAGCCCTGGCCTGTCCGAAG ACTGTTCTGAGTCTCAGCAAACGCCTGCAAGATCTTTGACCTTGCAAGAAGCACTGGAAGTTCGTAAGCCTCAGTTCATTTCTCGCTCAC AAGAACGGCTGAAGAAGCTTGAACACATGGTCCAGCAGAGGAAAGCCCAGCGGAAGGAGGACCTGAGGCAGAAGCAGAGCCTCCTTCCCA TCCGCACCAGCAAGAAGCAGTTCACGATTCCCCATCCTCTGAGTGATAACTTGTTCAAACCCAAAGAACGGTGCATTTCAGAGAAGGAGA TGCATATGCGATCTAAGAGAATCTATGATAACTTGCCGGAAGTTAAAAAGAAAAAAGAAGAACAAAGGAAAAGGGTGATCTTACAAAGTA ACAGACTCCGTGCCGAAGTCTTCAAAAAGCAATTACTGGACCAGCTCCTTCAAAGGAATGCGGTCTAACCACAGGCTGCCCTGCTGACCA CACTACCTGGACCTGGGAGGACTTCGAATGCTGGATAAGCCATTAAACTTAGCATTATCTTCATCATGGGAAAACACTTATTTTACTTTC GATTTTTTTTTTCCATAAAGGAAAACATCACTTCCTGAATTACTGACCCAAGCCAAACAGAAACAATAACCCTCGAGAAAATAGGTCAAC AATCTGTTGTGGGGAAACCACCTCCATGTAACCCACTGGATACAGTCCCCTTAATGTTTTTGCTTCTAAATTGTACCTTTTGCTTCTGAT >83766_83766_6_SMAD2-C10orf90_SMAD2_chr18_45394694_ENST00000402690_C10orf90_chr10_128202508_ENST00000544758_length(amino acids)=910AA_BP=218 MSSILPFTPPVVKRLLGWKKSAGGSGGAGGGEQNGQEEKWCEKAVKSLVKKLKKTGRLDELEKAITTQNCNTKCVTIPSTCSEIWGLSTP NTIDQWDTTGLYSFSEQTRSLDGRLQVSHRKGLPHVIYCRLWRWPDLHSHHELKAIENCEYAFNLKKDEVCVNPYHYQRVETPVLPPVLV PRHTEILTELPPLDDYTHSIPENTNFPAGIEPQSNYIPGLRDSYHSRRDQIALKNLQSDVTEAKSDFTKETLASQNTKMISSIVISQMID ENKSRENRASLPLPCAIAQSRAHHAKQSLANRSGVNIHRAFALLPGRLGIPAPSDERGPEAELPPKEERPCGGPRRGFASITITARRVGP PARALVWGTAGDSLCPKCRAEDTLFQAPPALANGAHPGRHQRSFACTEFSRNSSVVRLKVPEAHTGLCERRKYWVTHADDKETSFSPDTP LSGKSPLVFSSCVHLRVSQQCPDSIYYVDKSLSVPIEPPQIASPKMHRSVLSLNLNCSSHRLTADGVDGLVNREPISEALKQELLEGDQD LVGQRWNPGLQESHLKETPSLRRVHLGTGACPWSGSFPLENTELANVGANQVTVRKGEKDHTTHCHASDHANQLSIHIPGWSYRAVHTKV FSGSSKRQQGEVCMTVSAPPVEQKPTRHFLPIGDSSPSDDCLSRDLSEPTERRHQSFLKPRILFPGFLCPLQDVCASLQEDNGVQIESKF PKGDYTCCDLVVKIKECKKSEDPTTPEPSPAAPSPAPRDGAGSPGLSEDCSESQQTPARSLTLQEALEVRKPQFISRSQERLKKLEHMVQ QRKAQRKEDLRQKQSLLPIRTSKKQFTIPHPLSDNLFKPKERCISEKEMHMRSKRIYDNLPEVKKKKEEQRKRVILQSNRLRAEVFKKQL -------------------------------------------------------------- >83766_83766_7_SMAD2-C10orf90_SMAD2_chr18_45394694_ENST00000586040_C10orf90_chr10_128202508_ENST00000284694_length(transcript)=3553nt_BP=620nt AGGTTCGATACAAGAGGCTGTTTTCCTAGCGTGGCTTGCTGCCTTTGGTAAGAACATGTCGTCCATCTTGCCATTCACGCCGCCAGTTGT GAAGAGACTGCTGGGATGGAAGAAGTCAGCTGGTGGGTCTGGAGGAGCAGGCGGAGGAGAGCAGAATGGGCAGGAAGAAAAGTGGTGTGA GAAAGCAGTGAAAAGTCTGGTGAAGAAGCTAAAGAAAACAGGACGATTAGATGAGCTTGAGAAAGCCATCACCACTCAAAACTGTAATAC TAAATGTGTTACCATACCAAGGTCTCTTGATGGTCGTCTCCAGGTATCCCATCGAAAAGGATTGCCACATGTTATATATTGCCGATTATG GCGCTGGCCTGATCTTCACAGTCATCATGAACTCAAGGCAATTGAAAACTGCGAATATGCTTTTAATCTTAAAAAGGATGAAGTATGTGT AAACCCTTACCACTATCAGAGAGTTGAGACACCAGTTTTGCCTCCAGTATTAGTGCCCCGACACACCGAGATCCTAACAGAACTTCCGCC TCTGGATGACTATACTCACTCCATTCCAGAAAACACTAACTTCCCAGCAGGAATTGAGCCACAGAGTAATTATATTCCAGGATTACGGGA CAGCTACCACAGTAGAAGAGATCAAATTGCCCTTAAAAATCTCCAGTCTGATGTCACAGAGGCAAAATCTGACTTCACCAAGGAGACCCT GGCATCACAAAACACAAAAATGATTTCATCCATAGTCATCTCCCAGATGATTGATGAGAATAAGTCAAGAGAAAACAGGGCCTCCTTGCC CCTACCGTGTGCCATTGCTCAGTCTCGTGCACATCACGCCAAGCAATCTCTGGCTAACCGCAGCGGAGTCAACATTCACAGAGCATTTGC GTTACTTCCGGGCAGATTAGGAATCCCGGCACCGTCAGATGAGCGAGGACCTGAGGCAGAGCTGCCGCCCAAAGAGGAGAGACCCTGTGG GGGCCCCCGCAGAGGGTTTGCATCCATCACCATCACGGCCAGACGCGTGGGCCCCCCAGCCCGCGCCCTGGTGTGGGGGACTGCTGGGGA CTCTCTGTGCCCCAAGTGCAGGGCTGAGGACACACTGTTCCAGGCGCCCCCGGCTCTGGCCAATGGCGCCCATCCAGGTCGGCATCAGAG ATCTTTTGCCTGCACAGAGTTCTCCAGAAACAGCTCCGTGGTGCGGCTGAAGGTTCCCGAGGCCCACACTGGGTTGTGTGAGAGACGCAA GTACTGGGTCACCCATGCAGACGACAAAGAGACCAGTTTTTCTCCAGACACCCCACTGTCAGGAAAGAGCCCGCTGGTGTTCAGTTCCTG TGTCCACCTCAGGGTGTCTCAGCAGTGTCCAGATTCAATCTATTACGTAGACAAGTCTCTCTCCGTCCCCATTGAGCCACCTCAAATTGC CAGCCCCAAAATGCACAGATCCGTCCTGTCGCTCAACCTCAATTGTAGTTCCCACAGATTAACAGCAGATGGAGTAGATGGCCTAGTGAA CAGAGAGCCAATAAGCGAAGCCCTGAAGCAGGAGCTCCTGGAGGGAGACCAGGACCTCGTAGGCCAGCGCTGGAACCCAGGTTTACAAGA AAGTCACTTGAAGGAAACCCCATCGTTGAGGCGGGTGCATTTGGGGACCGGCGCTTGTCCTTGGAGTGGTTCTTTTCCATTGGAAAACAC AGAATTGGCAAATGTGGGAGCTAACCAAGTCACTGTAAGAAAAGGGGAAAAGGACCATACAACTCATTGTCACGCCAGCGATCATGCCAA CCAACTGTCCATTCACATTCCTGGCTGGAGTTACAGGGCAGTACACACAAAAGTATTTTCTGGAAGCAGCAAGAGGCAACAAGGAGAAGT ATGTATGACTGTGTCTGCTCCTCCAGTGGAACAGAAGCCCACTAGACATTTCCTTCCCATTGGGGATAGCTCTCCAAGCGATGACTGTCT GTCTAGAGACCTTTCTGAGCCCACAGAGAGACGACATCAAAGCTTCCTGAAACCCAGAATCCTTTTTCCTGGGTTTCTTTGCCCCTTACA AGATGTATGTGCATCTCTGCAGGAAGACAATGGTGTTCAGATAGAAAGCAAGTTCCCCAAAGGAGATTACACATGCTGTGACTTGGTTGT AAAAATAAAGGAATGTAAGAAGAGTGAGGACCCCACCACACCTGAGCCCTCCCCAGCAGCACCCTCGCCAGCACCCCGCGATGGAGCAGG GAGCCCTGGCCTGTCCGAAGACTGTTCTGAGTCTCAGCAAACGCCTGCAAGATCTTTGACCTTGCAAGAAGCACTGGAAGTTCGTAAGCC TCAGTTCATTTCTCGCTCACAAGAACGGCTGAAGAAGCTTGAACACATGGTCCAGCAGAGGAAAGCCCAGCGGAAGGAGGACCTGAGGCA GAAGCAGAGCCTCCTTCCCATCCGCACCAGCAAGAAGCAGTTCACGATTCCCCATCCTCTGAGTGATAACTTGTTCAAACCCAAAGAACG GTGCATTTCAGAGAAGGAGATGCATATGCGATCTAAGAGAATCTATGATAACTTGCCGGAAGTTAAAAAGAAAAAAGAAGAACAAAGGAA AAGGGTGATCTTACAAAGTAACAGACTCCGTGCCGAAGTCTTCAAAAAGCAATTACTGGACCAGCTCCTTCAAAGGAATGCGGTCTAACC ACAGGCTGCCCTGCTGACCACACTACCTGGACCTGGGAGGACTTCGAATGCTGGATAAGCCATTAAACTTAGCATTATCTTCATCATGGG AAAACACTTATTTTACTTTCGATTTTTTTTTTCCATAAAGGAAAACATCACTTCCTGAATTACTGACCCAAGCCAAACAGAAACAATAAC CCTCGAGAAAATAGGTCAACAATCTGTTGTGGGGAAACCACCTCCATGTAACCCACTGGATACAGTCCCCTTAATGTTTTTGCTTCTAAA TTGTACCTTTTGCTTCTGATTTCTTCTCCCCTGCTGTTTCCTGCCCATCAGAGAGGCCTGATACAAGCAAGTTTGTTTACATCCCTGGGG AATCTTTTACATCAAACTTTTGGGATCCAAATCCATCTCCTTTTAAATTTCAATCTCAGCACCTGCCAGTTATGCAAATGCCAAAATGTG GGTCATCATATAGTATATTTGAAACCTTTCTGAACATGTACACCACCCAATGCTAGAGGCTGACTTGGAAACCGGTGGGTGCAATGCCCG AGGCTGTGGAACAATCAGCCCATCTCTTTGTGACCTGGAGCAGTCAGAGGGCCCTCAGTCACCCCGCCCCATTCCTCACCAGAGAAAAGA ATCCATTTCTATGGAAGCTCTGACGTAACTTCAGTGTTTTCTACAATACTCCTCCTGCCCCGCCCCATTAAAACAGTTCTTTTGTTAAGA AATAGCCTAATGGTCCAACTTTGCTGTCTGTTCTTCCAAATGTTTATAATACACATTATTTATAAATATGTCTGTTTGGGAAGCTAAGAA >83766_83766_7_SMAD2-C10orf90_SMAD2_chr18_45394694_ENST00000586040_C10orf90_chr10_128202508_ENST00000284694_length(amino acids)=880AA_BP=188 MSSILPFTPPVVKRLLGWKKSAGGSGGAGGGEQNGQEEKWCEKAVKSLVKKLKKTGRLDELEKAITTQNCNTKCVTIPRSLDGRLQVSHR KGLPHVIYCRLWRWPDLHSHHELKAIENCEYAFNLKKDEVCVNPYHYQRVETPVLPPVLVPRHTEILTELPPLDDYTHSIPENTNFPAGI EPQSNYIPGLRDSYHSRRDQIALKNLQSDVTEAKSDFTKETLASQNTKMISSIVISQMIDENKSRENRASLPLPCAIAQSRAHHAKQSLA NRSGVNIHRAFALLPGRLGIPAPSDERGPEAELPPKEERPCGGPRRGFASITITARRVGPPARALVWGTAGDSLCPKCRAEDTLFQAPPA LANGAHPGRHQRSFACTEFSRNSSVVRLKVPEAHTGLCERRKYWVTHADDKETSFSPDTPLSGKSPLVFSSCVHLRVSQQCPDSIYYVDK SLSVPIEPPQIASPKMHRSVLSLNLNCSSHRLTADGVDGLVNREPISEALKQELLEGDQDLVGQRWNPGLQESHLKETPSLRRVHLGTGA CPWSGSFPLENTELANVGANQVTVRKGEKDHTTHCHASDHANQLSIHIPGWSYRAVHTKVFSGSSKRQQGEVCMTVSAPPVEQKPTRHFL PIGDSSPSDDCLSRDLSEPTERRHQSFLKPRILFPGFLCPLQDVCASLQEDNGVQIESKFPKGDYTCCDLVVKIKECKKSEDPTTPEPSP AAPSPAPRDGAGSPGLSEDCSESQQTPARSLTLQEALEVRKPQFISRSQERLKKLEHMVQQRKAQRKEDLRQKQSLLPIRTSKKQFTIPH -------------------------------------------------------------- >83766_83766_8_SMAD2-C10orf90_SMAD2_chr18_45394694_ENST00000586040_C10orf90_chr10_128202508_ENST00000454341_length(transcript)=3262nt_BP=620nt AGGTTCGATACAAGAGGCTGTTTTCCTAGCGTGGCTTGCTGCCTTTGGTAAGAACATGTCGTCCATCTTGCCATTCACGCCGCCAGTTGT GAAGAGACTGCTGGGATGGAAGAAGTCAGCTGGTGGGTCTGGAGGAGCAGGCGGAGGAGAGCAGAATGGGCAGGAAGAAAAGTGGTGTGA GAAAGCAGTGAAAAGTCTGGTGAAGAAGCTAAAGAAAACAGGACGATTAGATGAGCTTGAGAAAGCCATCACCACTCAAAACTGTAATAC TAAATGTGTTACCATACCAAGGTCTCTTGATGGTCGTCTCCAGGTATCCCATCGAAAAGGATTGCCACATGTTATATATTGCCGATTATG GCGCTGGCCTGATCTTCACAGTCATCATGAACTCAAGGCAATTGAAAACTGCGAATATGCTTTTAATCTTAAAAAGGATGAAGTATGTGT AAACCCTTACCACTATCAGAGAGTTGAGACACCAGTTTTGCCTCCAGTATTAGTGCCCCGACACACCGAGATCCTAACAGAACTTCCGCC TCTGGATGACTATACTCACTCCATTCCAGAAAACACTAACTTCCCAGCAGGAATTGAGCCACAGAGTAATTATATTCCAGGATTACGGGA CAGCTACCACAGTAGAAGAGATCAAATTGCCCTTAAAAATCTCCAGTCTGATGTCACAGAGGCAAAATCTGACTTCACCAAGGAGACCCT GGCATCACAAAACACAAAAATGATTTCATCCATAGTCATCTCCCAGATGATTGATGAGAATAAGTCAAGAGAAAACAGGGCCTCCTTGCC CCTACCGTGTGCCATTGCTCAGTCTCGTGCACATCACGCCAAGCAATCTCTGGCTAACCGCAGCGGAGTCAACATTCACAGAGCATTTGC GTTACTTCCGGGCAGATTAGGAATCCCGGCACCGTCAGATGAGCGAGGACCTGAGGCAGAGCTGCCGCCCAAAGAGGAGAGACCCTGTGG GGGCCCCCGCAGAGGGTTTGCATCCATCACCATCACGGCCAGACGCGTGGGCCCCCCAGCCCGCGCCCTGGTGTGGGGGACTGCTGGGGA CTCTCTGTGCCCCAAGTGCAGGGCTGAGGACACACTGTTCCAGGCGCCCCCGGCTCTGGCCAATGGCGCCCATCCAGGTCGGCATCAGAG ATCTTTTGCCTGCACAGAGTTCTCCAGAAACAGCTCCGTGGTGCGGCTGAAGGTTCCCGAGGCCCACACTGGGTTGTGTGAGAGACGCAA GTACTGGGTCACCCATGCAGACGACAAAGAGACCAGTTTTTCTCCAGACACCCCACTGTCAGGAAAGAGCCCGCTGGTGTTCAGTTCCTG TGTCCACCTCAGGGTGTCTCAGCAGTGTCCAGATTCAATCTATTACGTAGACAAGTCTCTCTCCGTCCCCATTGAGCCACCTCAAATTGC CAGCCCCAAAATGCACAGATCCGTCCTGTCGCTCAACCTCAATTGTAGTTCCCACAGATTAACAGCAGATGGAGTAGATGGCCTAGTGAA CAGAGAGCCAATAAGCGAAGCCCTGAAGCAGGAGCTCCTGGAGGGAGACCAGGACCTCGTAGGCCAGCGCTGGAACCCAGGTTTACAAGA AAGTCACTTGAAGGAAACCCCATCGTTGAGGCGGGTGCATTTGGGGACCGGCGCTTGTCCTTGGAGTGGTTCTTTTCCATTGGAAAACAC AGAATTGGCAAATGTGGGAGCTAACCAAGTCACTGTAAGAAAAGGGGAAAAGGACCATACAACTCATTGTCACGCCAGCGATCATGCCAA CCAACTGTCCATTCACATTCCTGGCTGGAGTTACAGGGCAGGAGATTACACATGCTGTGACTTGGTTGTAAAAATAAAGGAATGTAAGAA GAGTGAGGACCCCACCACACCTGAGCCCTCCCCAGCAGCACCCTCGCCAGCACCCCGCGATGGAGCAGGGAGCCCTGGCCTGTCCGAAGA CTGTTCTGAGTCTCAGCAAACGCCTGCAAGATCTTTGACCTTGCAAGAAGCACTGGAAGTTCGTAAGCCTCAGTTCATTTCTCGCTCACA AGAACGGCTGAAGAAGCTTGAACACATGGTCCAGCAGAGGAAAGCCCAGCGGAAGGAGGACCTGAGGCAGAAGCAGAGCCTCCTTCCCAT CCGCACCAGCAAGAAGCAGTTCACGATTCCCCATCCTCTGAGTGATAACTTGTTCAAACCCAAAGAACGGTGCATTTCAGAGAAGGAGAT GCATATGCGATCTAAGAGAATCTATGATAACTTGCCGGAAGTTAAAAAGAAAAAAGAAGAACAAAGGAAAAGGGTGATCTTACAAAGTAA CAGACTCCGTGCCGAAGTCTTCAAAAAGCAATTACTGGACCAGCTCCTTCAAAGGAATGCGGTCTAACCACAGGCTGCCCTGCTGACCAC ACTACCTGGACCTGGGAGGACTTCGAATGCTGGATAAGCCATTAAACTTAGCATTATCTTCATCATGGGAAAACACTTATTTTACTTTCG ATTTTTTTTTTCCATAAAGGAAAACATCACTTCCTGAATTACTGACCCAAGCCAAACAGAAACAATAACCCTCGAGAAAATAGGTCAACA ATCTGTTGTGGGGAAACCACCTCCATGTAACCCACTGGATACAGTCCCCTTAATGTTTTTGCTTCTAAATTGTACCTTTTGCTTCTGATT TCTTCTCCCCTGCTGTTTCCTGCCCATCAGAGAGGCCTGATACAAGCAAGTTTGTTTACATCCCTGGGGAATCTTTTACATCAAACTTTT GGGATCCAAATCCATCTCCTTTTAAATTTCAATCTCAGCACCTGCCAGTTATGCAAATGCCAAAATGTGGGTCATCATATAGTATATTTG AAACCTTTCTGAACATGTACACCACCCAATGCTAGAGGCTGACTTGGAAACCGGTGGGTGCAATGCCCGAGGCTGTGGAACAATCAGCCC ATCTCTTTGTGACCTGGAGCAGTCAGAGGGCCCTCAGTCACCCCGCCCCATTCCTCACCAGAGAAAAGAATCCATTTCTATGGAAGCTCT GACGTAACTTCAGTGTTTTCTACAATACTCCTCCTGCCCCGCCCCATTAAAACAGTTCTTTTGTTAAGAAATAGCCTAATGGTCCAACTT TGCTGTCTGTTCTTCCAAATGTTTATAATACACATTATTTATAAATATGTCTGTTTGGGAAGCTAAGAACAAGCTAGTTTTTACAACACA >83766_83766_8_SMAD2-C10orf90_SMAD2_chr18_45394694_ENST00000586040_C10orf90_chr10_128202508_ENST00000454341_length(amino acids)=783AA_BP=188 MSSILPFTPPVVKRLLGWKKSAGGSGGAGGGEQNGQEEKWCEKAVKSLVKKLKKTGRLDELEKAITTQNCNTKCVTIPRSLDGRLQVSHR KGLPHVIYCRLWRWPDLHSHHELKAIENCEYAFNLKKDEVCVNPYHYQRVETPVLPPVLVPRHTEILTELPPLDDYTHSIPENTNFPAGI EPQSNYIPGLRDSYHSRRDQIALKNLQSDVTEAKSDFTKETLASQNTKMISSIVISQMIDENKSRENRASLPLPCAIAQSRAHHAKQSLA NRSGVNIHRAFALLPGRLGIPAPSDERGPEAELPPKEERPCGGPRRGFASITITARRVGPPARALVWGTAGDSLCPKCRAEDTLFQAPPA LANGAHPGRHQRSFACTEFSRNSSVVRLKVPEAHTGLCERRKYWVTHADDKETSFSPDTPLSGKSPLVFSSCVHLRVSQQCPDSIYYVDK SLSVPIEPPQIASPKMHRSVLSLNLNCSSHRLTADGVDGLVNREPISEALKQELLEGDQDLVGQRWNPGLQESHLKETPSLRRVHLGTGA CPWSGSFPLENTELANVGANQVTVRKGEKDHTTHCHASDHANQLSIHIPGWSYRAGDYTCCDLVVKIKECKKSEDPTTPEPSPAAPSPAP RDGAGSPGLSEDCSESQQTPARSLTLQEALEVRKPQFISRSQERLKKLEHMVQQRKAQRKEDLRQKQSLLPIRTSKKQFTIPHPLSDNLF -------------------------------------------------------------- >83766_83766_9_SMAD2-C10orf90_SMAD2_chr18_45394694_ENST00000586040_C10orf90_chr10_128202508_ENST00000544758_length(transcript)=2997nt_BP=620nt AGGTTCGATACAAGAGGCTGTTTTCCTAGCGTGGCTTGCTGCCTTTGGTAAGAACATGTCGTCCATCTTGCCATTCACGCCGCCAGTTGT GAAGAGACTGCTGGGATGGAAGAAGTCAGCTGGTGGGTCTGGAGGAGCAGGCGGAGGAGAGCAGAATGGGCAGGAAGAAAAGTGGTGTGA GAAAGCAGTGAAAAGTCTGGTGAAGAAGCTAAAGAAAACAGGACGATTAGATGAGCTTGAGAAAGCCATCACCACTCAAAACTGTAATAC TAAATGTGTTACCATACCAAGGTCTCTTGATGGTCGTCTCCAGGTATCCCATCGAAAAGGATTGCCACATGTTATATATTGCCGATTATG GCGCTGGCCTGATCTTCACAGTCATCATGAACTCAAGGCAATTGAAAACTGCGAATATGCTTTTAATCTTAAAAAGGATGAAGTATGTGT AAACCCTTACCACTATCAGAGAGTTGAGACACCAGTTTTGCCTCCAGTATTAGTGCCCCGACACACCGAGATCCTAACAGAACTTCCGCC TCTGGATGACTATACTCACTCCATTCCAGAAAACACTAACTTCCCAGCAGGAATTGAGCCACAGAGTAATTATATTCCAGGATTACGGGA CAGCTACCACAGTAGAAGAGATCAAATTGCCCTTAAAAATCTCCAGTCTGATGTCACAGAGGCAAAATCTGACTTCACCAAGGAGACCCT GGCATCACAAAACACAAAAATGATTTCATCCATAGTCATCTCCCAGATGATTGATGAGAATAAGTCAAGAGAAAACAGGGCCTCCTTGCC CCTACCGTGTGCCATTGCTCAGTCTCGTGCACATCACGCCAAGCAATCTCTGGCTAACCGCAGCGGAGTCAACATTCACAGAGCATTTGC GTTACTTCCGGGCAGATTAGGAATCCCGGCACCGTCAGATGAGCGAGGACCTGAGGCAGAGCTGCCGCCCAAAGAGGAGAGACCCTGTGG GGGCCCCCGCAGAGGGTTTGCATCCATCACCATCACGGCCAGACGCGTGGGCCCCCCAGCCCGCGCCCTGGTGTGGGGGACTGCTGGGGA CTCTCTGTGCCCCAAGTGCAGGGCTGAGGACACACTGTTCCAGGCGCCCCCGGCTCTGGCCAATGGCGCCCATCCAGGTCGGCATCAGAG ATCTTTTGCCTGCACAGAGTTCTCCAGAAACAGCTCCGTGGTGCGGCTGAAGGTTCCCGAGGCCCACACTGGGTTGTGTGAGAGACGCAA GTACTGGGTCACCCATGCAGACGACAAAGAGACCAGTTTTTCTCCAGACACCCCACTGTCAGGAAAGAGCCCGCTGGTGTTCAGTTCCTG TGTCCACCTCAGGGTGTCTCAGCAGTGTCCAGATTCAATCTATTACGTAGACAAGTCTCTCTCCGTCCCCATTGAGCCACCTCAAATTGC CAGCCCCAAAATGCACAGATCCGTCCTGTCGCTCAACCTCAATTGTAGTTCCCACAGATTAACAGCAGATGGAGTAGATGGCCTAGTGAA CAGAGAGCCAATAAGCGAAGCCCTGAAGCAGGAGCTCCTGGAGGGAGACCAGGACCTCGTAGGCCAGCGCTGGAACCCAGGTTTACAAGA AAGTCACTTGAAGGAAACCCCATCGTTGAGGCGGGTGCATTTGGGGACCGGCGCTTGTCCTTGGAGTGGTTCTTTTCCATTGGAAAACAC AGAATTGGCAAATGTGGGAGCTAACCAAGTCACTGTAAGAAAAGGGGAAAAGGACCATACAACTCATTGTCACGCCAGCGATCATGCCAA CCAACTGTCCATTCACATTCCTGGCTGGAGTTACAGGGCAGTACACACAAAAGTATTTTCTGGAAGCAGCAAGAGGCAACAAGGAGAAGT ATGTATGACTGTGTCTGCTCCTCCAGTGGAACAGAAGCCCACTAGACATTTCCTTCCCATTGGGGATAGCTCTCCAAGCGATGACTGTCT GTCTAGAGACCTTTCTGAGCCCACAGAGAGACGACATCAAAGCTTCCTGAAACCCAGAATCCTTTTTCCTGGGTTTCTTTGCCCCTTACA AGATGTATGTGCATCTCTGCAGGAAGACAATGGTGTTCAGATAGAAAGCAAGTTCCCCAAAGGAGATTACACATGCTGTGACTTGGTTGT AAAAATAAAGGAATGTAAGAAGAGTGAGGACCCCACCACACCTGAGCCCTCCCCAGCAGCACCCTCGCCAGCACCCCGCGATGGAGCAGG GAGCCCTGGCCTGTCCGAAGACTGTTCTGAGTCTCAGCAAACGCCTGCAAGATCTTTGACCTTGCAAGAAGCACTGGAAGTTCGTAAGCC TCAGTTCATTTCTCGCTCACAAGAACGGCTGAAGAAGCTTGAACACATGGTCCAGCAGAGGAAAGCCCAGCGGAAGGAGGACCTGAGGCA GAAGCAGAGCCTCCTTCCCATCCGCACCAGCAAGAAGCAGTTCACGATTCCCCATCCTCTGAGTGATAACTTGTTCAAACCCAAAGAACG GTGCATTTCAGAGAAGGAGATGCATATGCGATCTAAGAGAATCTATGATAACTTGCCGGAAGTTAAAAAGAAAAAAGAAGAACAAAGGAA AAGGGTGATCTTACAAAGTAACAGACTCCGTGCCGAAGTCTTCAAAAAGCAATTACTGGACCAGCTCCTTCAAAGGAATGCGGTCTAACC ACAGGCTGCCCTGCTGACCACACTACCTGGACCTGGGAGGACTTCGAATGCTGGATAAGCCATTAAACTTAGCATTATCTTCATCATGGG AAAACACTTATTTTACTTTCGATTTTTTTTTTCCATAAAGGAAAACATCACTTCCTGAATTACTGACCCAAGCCAAACAGAAACAATAAC CCTCGAGAAAATAGGTCAACAATCTGTTGTGGGGAAACCACCTCCATGTAACCCACTGGATACAGTCCCCTTAATGTTTTTGCTTCTAAA >83766_83766_9_SMAD2-C10orf90_SMAD2_chr18_45394694_ENST00000586040_C10orf90_chr10_128202508_ENST00000544758_length(amino acids)=880AA_BP=188 MSSILPFTPPVVKRLLGWKKSAGGSGGAGGGEQNGQEEKWCEKAVKSLVKKLKKTGRLDELEKAITTQNCNTKCVTIPRSLDGRLQVSHR KGLPHVIYCRLWRWPDLHSHHELKAIENCEYAFNLKKDEVCVNPYHYQRVETPVLPPVLVPRHTEILTELPPLDDYTHSIPENTNFPAGI EPQSNYIPGLRDSYHSRRDQIALKNLQSDVTEAKSDFTKETLASQNTKMISSIVISQMIDENKSRENRASLPLPCAIAQSRAHHAKQSLA NRSGVNIHRAFALLPGRLGIPAPSDERGPEAELPPKEERPCGGPRRGFASITITARRVGPPARALVWGTAGDSLCPKCRAEDTLFQAPPA LANGAHPGRHQRSFACTEFSRNSSVVRLKVPEAHTGLCERRKYWVTHADDKETSFSPDTPLSGKSPLVFSSCVHLRVSQQCPDSIYYVDK SLSVPIEPPQIASPKMHRSVLSLNLNCSSHRLTADGVDGLVNREPISEALKQELLEGDQDLVGQRWNPGLQESHLKETPSLRRVHLGTGA CPWSGSFPLENTELANVGANQVTVRKGEKDHTTHCHASDHANQLSIHIPGWSYRAVHTKVFSGSSKRQQGEVCMTVSAPPVEQKPTRHFL PIGDSSPSDDCLSRDLSEPTERRHQSFLKPRILFPGFLCPLQDVCASLQEDNGVQIESKFPKGDYTCCDLVVKIKECKKSEDPTTPEPSP AAPSPAPRDGAGSPGLSEDCSESQQTPARSLTLQEALEVRKPQFISRSQERLKKLEHMVQQRKAQRKEDLRQKQSLLPIRTSKKQFTIPH -------------------------------------------------------------- >83766_83766_10_SMAD2-C10orf90_SMAD2_chr18_45394694_ENST00000591214_C10orf90_chr10_128202508_ENST00000284694_length(transcript)=3594nt_BP=661nt GGAGAAGCAGCTCGCCAGCCAGCAGCCCGCCAGCCGCCGGGAGGTTCGATACAAGAGGCTGTTTTCCTAGCGTGGCTTGCTGCCTTTGGT AAGAACATGTCGTCCATCTTGCCATTCACGCCGCCAGTTGTGAAGAGACTGCTGGGATGGAAGAAGTCAGCTGGTGGGTCTGGAGGAGCA GGCGGAGGAGAGCAGAATGGGCAGGAAGAAAAGTGGTGTGAGAAAGCAGTGAAAAGTCTGGTGAAGAAGCTAAAGAAAACAGGACGATTA GATGAGCTTGAGAAAGCCATCACCACTCAAAACTGTAATACTAAATGTGTTACCATACCAAGGTCTCTTGATGGTCGTCTCCAGGTATCC CATCGAAAAGGATTGCCACATGTTATATATTGCCGATTATGGCGCTGGCCTGATCTTCACAGTCATCATGAACTCAAGGCAATTGAAAAC TGCGAATATGCTTTTAATCTTAAAAAGGATGAAGTATGTGTAAACCCTTACCACTATCAGAGAGTTGAGACACCAGTTTTGCCTCCAGTA TTAGTGCCCCGACACACCGAGATCCTAACAGAACTTCCGCCTCTGGATGACTATACTCACTCCATTCCAGAAAACACTAACTTCCCAGCA GGAATTGAGCCACAGAGTAATTATATTCCAGGATTACGGGACAGCTACCACAGTAGAAGAGATCAAATTGCCCTTAAAAATCTCCAGTCT GATGTCACAGAGGCAAAATCTGACTTCACCAAGGAGACCCTGGCATCACAAAACACAAAAATGATTTCATCCATAGTCATCTCCCAGATG ATTGATGAGAATAAGTCAAGAGAAAACAGGGCCTCCTTGCCCCTACCGTGTGCCATTGCTCAGTCTCGTGCACATCACGCCAAGCAATCT CTGGCTAACCGCAGCGGAGTCAACATTCACAGAGCATTTGCGTTACTTCCGGGCAGATTAGGAATCCCGGCACCGTCAGATGAGCGAGGA CCTGAGGCAGAGCTGCCGCCCAAAGAGGAGAGACCCTGTGGGGGCCCCCGCAGAGGGTTTGCATCCATCACCATCACGGCCAGACGCGTG GGCCCCCCAGCCCGCGCCCTGGTGTGGGGGACTGCTGGGGACTCTCTGTGCCCCAAGTGCAGGGCTGAGGACACACTGTTCCAGGCGCCC CCGGCTCTGGCCAATGGCGCCCATCCAGGTCGGCATCAGAGATCTTTTGCCTGCACAGAGTTCTCCAGAAACAGCTCCGTGGTGCGGCTG AAGGTTCCCGAGGCCCACACTGGGTTGTGTGAGAGACGCAAGTACTGGGTCACCCATGCAGACGACAAAGAGACCAGTTTTTCTCCAGAC ACCCCACTGTCAGGAAAGAGCCCGCTGGTGTTCAGTTCCTGTGTCCACCTCAGGGTGTCTCAGCAGTGTCCAGATTCAATCTATTACGTA GACAAGTCTCTCTCCGTCCCCATTGAGCCACCTCAAATTGCCAGCCCCAAAATGCACAGATCCGTCCTGTCGCTCAACCTCAATTGTAGT TCCCACAGATTAACAGCAGATGGAGTAGATGGCCTAGTGAACAGAGAGCCAATAAGCGAAGCCCTGAAGCAGGAGCTCCTGGAGGGAGAC CAGGACCTCGTAGGCCAGCGCTGGAACCCAGGTTTACAAGAAAGTCACTTGAAGGAAACCCCATCGTTGAGGCGGGTGCATTTGGGGACC GGCGCTTGTCCTTGGAGTGGTTCTTTTCCATTGGAAAACACAGAATTGGCAAATGTGGGAGCTAACCAAGTCACTGTAAGAAAAGGGGAA AAGGACCATACAACTCATTGTCACGCCAGCGATCATGCCAACCAACTGTCCATTCACATTCCTGGCTGGAGTTACAGGGCAGTACACACA AAAGTATTTTCTGGAAGCAGCAAGAGGCAACAAGGAGAAGTATGTATGACTGTGTCTGCTCCTCCAGTGGAACAGAAGCCCACTAGACAT TTCCTTCCCATTGGGGATAGCTCTCCAAGCGATGACTGTCTGTCTAGAGACCTTTCTGAGCCCACAGAGAGACGACATCAAAGCTTCCTG AAACCCAGAATCCTTTTTCCTGGGTTTCTTTGCCCCTTACAAGATGTATGTGCATCTCTGCAGGAAGACAATGGTGTTCAGATAGAAAGC AAGTTCCCCAAAGGAGATTACACATGCTGTGACTTGGTTGTAAAAATAAAGGAATGTAAGAAGAGTGAGGACCCCACCACACCTGAGCCC TCCCCAGCAGCACCCTCGCCAGCACCCCGCGATGGAGCAGGGAGCCCTGGCCTGTCCGAAGACTGTTCTGAGTCTCAGCAAACGCCTGCA AGATCTTTGACCTTGCAAGAAGCACTGGAAGTTCGTAAGCCTCAGTTCATTTCTCGCTCACAAGAACGGCTGAAGAAGCTTGAACACATG GTCCAGCAGAGGAAAGCCCAGCGGAAGGAGGACCTGAGGCAGAAGCAGAGCCTCCTTCCCATCCGCACCAGCAAGAAGCAGTTCACGATT CCCCATCCTCTGAGTGATAACTTGTTCAAACCCAAAGAACGGTGCATTTCAGAGAAGGAGATGCATATGCGATCTAAGAGAATCTATGAT AACTTGCCGGAAGTTAAAAAGAAAAAAGAAGAACAAAGGAAAAGGGTGATCTTACAAAGTAACAGACTCCGTGCCGAAGTCTTCAAAAAG CAATTACTGGACCAGCTCCTTCAAAGGAATGCGGTCTAACCACAGGCTGCCCTGCTGACCACACTACCTGGACCTGGGAGGACTTCGAAT GCTGGATAAGCCATTAAACTTAGCATTATCTTCATCATGGGAAAACACTTATTTTACTTTCGATTTTTTTTTTCCATAAAGGAAAACATC ACTTCCTGAATTACTGACCCAAGCCAAACAGAAACAATAACCCTCGAGAAAATAGGTCAACAATCTGTTGTGGGGAAACCACCTCCATGT AACCCACTGGATACAGTCCCCTTAATGTTTTTGCTTCTAAATTGTACCTTTTGCTTCTGATTTCTTCTCCCCTGCTGTTTCCTGCCCATC AGAGAGGCCTGATACAAGCAAGTTTGTTTACATCCCTGGGGAATCTTTTACATCAAACTTTTGGGATCCAAATCCATCTCCTTTTAAATT TCAATCTCAGCACCTGCCAGTTATGCAAATGCCAAAATGTGGGTCATCATATAGTATATTTGAAACCTTTCTGAACATGTACACCACCCA ATGCTAGAGGCTGACTTGGAAACCGGTGGGTGCAATGCCCGAGGCTGTGGAACAATCAGCCCATCTCTTTGTGACCTGGAGCAGTCAGAG GGCCCTCAGTCACCCCGCCCCATTCCTCACCAGAGAAAAGAATCCATTTCTATGGAAGCTCTGACGTAACTTCAGTGTTTTCTACAATAC TCCTCCTGCCCCGCCCCATTAAAACAGTTCTTTTGTTAAGAAATAGCCTAATGGTCCAACTTTGCTGTCTGTTCTTCCAAATGTTTATAA >83766_83766_10_SMAD2-C10orf90_SMAD2_chr18_45394694_ENST00000591214_C10orf90_chr10_128202508_ENST00000284694_length(amino acids)=880AA_BP=188 MSSILPFTPPVVKRLLGWKKSAGGSGGAGGGEQNGQEEKWCEKAVKSLVKKLKKTGRLDELEKAITTQNCNTKCVTIPRSLDGRLQVSHR KGLPHVIYCRLWRWPDLHSHHELKAIENCEYAFNLKKDEVCVNPYHYQRVETPVLPPVLVPRHTEILTELPPLDDYTHSIPENTNFPAGI EPQSNYIPGLRDSYHSRRDQIALKNLQSDVTEAKSDFTKETLASQNTKMISSIVISQMIDENKSRENRASLPLPCAIAQSRAHHAKQSLA NRSGVNIHRAFALLPGRLGIPAPSDERGPEAELPPKEERPCGGPRRGFASITITARRVGPPARALVWGTAGDSLCPKCRAEDTLFQAPPA LANGAHPGRHQRSFACTEFSRNSSVVRLKVPEAHTGLCERRKYWVTHADDKETSFSPDTPLSGKSPLVFSSCVHLRVSQQCPDSIYYVDK SLSVPIEPPQIASPKMHRSVLSLNLNCSSHRLTADGVDGLVNREPISEALKQELLEGDQDLVGQRWNPGLQESHLKETPSLRRVHLGTGA CPWSGSFPLENTELANVGANQVTVRKGEKDHTTHCHASDHANQLSIHIPGWSYRAVHTKVFSGSSKRQQGEVCMTVSAPPVEQKPTRHFL PIGDSSPSDDCLSRDLSEPTERRHQSFLKPRILFPGFLCPLQDVCASLQEDNGVQIESKFPKGDYTCCDLVVKIKECKKSEDPTTPEPSP AAPSPAPRDGAGSPGLSEDCSESQQTPARSLTLQEALEVRKPQFISRSQERLKKLEHMVQQRKAQRKEDLRQKQSLLPIRTSKKQFTIPH -------------------------------------------------------------- >83766_83766_11_SMAD2-C10orf90_SMAD2_chr18_45394694_ENST00000591214_C10orf90_chr10_128202508_ENST00000454341_length(transcript)=3303nt_BP=661nt GGAGAAGCAGCTCGCCAGCCAGCAGCCCGCCAGCCGCCGGGAGGTTCGATACAAGAGGCTGTTTTCCTAGCGTGGCTTGCTGCCTTTGGT AAGAACATGTCGTCCATCTTGCCATTCACGCCGCCAGTTGTGAAGAGACTGCTGGGATGGAAGAAGTCAGCTGGTGGGTCTGGAGGAGCA GGCGGAGGAGAGCAGAATGGGCAGGAAGAAAAGTGGTGTGAGAAAGCAGTGAAAAGTCTGGTGAAGAAGCTAAAGAAAACAGGACGATTA GATGAGCTTGAGAAAGCCATCACCACTCAAAACTGTAATACTAAATGTGTTACCATACCAAGGTCTCTTGATGGTCGTCTCCAGGTATCC CATCGAAAAGGATTGCCACATGTTATATATTGCCGATTATGGCGCTGGCCTGATCTTCACAGTCATCATGAACTCAAGGCAATTGAAAAC TGCGAATATGCTTTTAATCTTAAAAAGGATGAAGTATGTGTAAACCCTTACCACTATCAGAGAGTTGAGACACCAGTTTTGCCTCCAGTA TTAGTGCCCCGACACACCGAGATCCTAACAGAACTTCCGCCTCTGGATGACTATACTCACTCCATTCCAGAAAACACTAACTTCCCAGCA GGAATTGAGCCACAGAGTAATTATATTCCAGGATTACGGGACAGCTACCACAGTAGAAGAGATCAAATTGCCCTTAAAAATCTCCAGTCT GATGTCACAGAGGCAAAATCTGACTTCACCAAGGAGACCCTGGCATCACAAAACACAAAAATGATTTCATCCATAGTCATCTCCCAGATG ATTGATGAGAATAAGTCAAGAGAAAACAGGGCCTCCTTGCCCCTACCGTGTGCCATTGCTCAGTCTCGTGCACATCACGCCAAGCAATCT CTGGCTAACCGCAGCGGAGTCAACATTCACAGAGCATTTGCGTTACTTCCGGGCAGATTAGGAATCCCGGCACCGTCAGATGAGCGAGGA CCTGAGGCAGAGCTGCCGCCCAAAGAGGAGAGACCCTGTGGGGGCCCCCGCAGAGGGTTTGCATCCATCACCATCACGGCCAGACGCGTG GGCCCCCCAGCCCGCGCCCTGGTGTGGGGGACTGCTGGGGACTCTCTGTGCCCCAAGTGCAGGGCTGAGGACACACTGTTCCAGGCGCCC CCGGCTCTGGCCAATGGCGCCCATCCAGGTCGGCATCAGAGATCTTTTGCCTGCACAGAGTTCTCCAGAAACAGCTCCGTGGTGCGGCTG AAGGTTCCCGAGGCCCACACTGGGTTGTGTGAGAGACGCAAGTACTGGGTCACCCATGCAGACGACAAAGAGACCAGTTTTTCTCCAGAC ACCCCACTGTCAGGAAAGAGCCCGCTGGTGTTCAGTTCCTGTGTCCACCTCAGGGTGTCTCAGCAGTGTCCAGATTCAATCTATTACGTA GACAAGTCTCTCTCCGTCCCCATTGAGCCACCTCAAATTGCCAGCCCCAAAATGCACAGATCCGTCCTGTCGCTCAACCTCAATTGTAGT TCCCACAGATTAACAGCAGATGGAGTAGATGGCCTAGTGAACAGAGAGCCAATAAGCGAAGCCCTGAAGCAGGAGCTCCTGGAGGGAGAC CAGGACCTCGTAGGCCAGCGCTGGAACCCAGGTTTACAAGAAAGTCACTTGAAGGAAACCCCATCGTTGAGGCGGGTGCATTTGGGGACC GGCGCTTGTCCTTGGAGTGGTTCTTTTCCATTGGAAAACACAGAATTGGCAAATGTGGGAGCTAACCAAGTCACTGTAAGAAAAGGGGAA AAGGACCATACAACTCATTGTCACGCCAGCGATCATGCCAACCAACTGTCCATTCACATTCCTGGCTGGAGTTACAGGGCAGGAGATTAC ACATGCTGTGACTTGGTTGTAAAAATAAAGGAATGTAAGAAGAGTGAGGACCCCACCACACCTGAGCCCTCCCCAGCAGCACCCTCGCCA GCACCCCGCGATGGAGCAGGGAGCCCTGGCCTGTCCGAAGACTGTTCTGAGTCTCAGCAAACGCCTGCAAGATCTTTGACCTTGCAAGAA GCACTGGAAGTTCGTAAGCCTCAGTTCATTTCTCGCTCACAAGAACGGCTGAAGAAGCTTGAACACATGGTCCAGCAGAGGAAAGCCCAG CGGAAGGAGGACCTGAGGCAGAAGCAGAGCCTCCTTCCCATCCGCACCAGCAAGAAGCAGTTCACGATTCCCCATCCTCTGAGTGATAAC TTGTTCAAACCCAAAGAACGGTGCATTTCAGAGAAGGAGATGCATATGCGATCTAAGAGAATCTATGATAACTTGCCGGAAGTTAAAAAG AAAAAAGAAGAACAAAGGAAAAGGGTGATCTTACAAAGTAACAGACTCCGTGCCGAAGTCTTCAAAAAGCAATTACTGGACCAGCTCCTT CAAAGGAATGCGGTCTAACCACAGGCTGCCCTGCTGACCACACTACCTGGACCTGGGAGGACTTCGAATGCTGGATAAGCCATTAAACTT AGCATTATCTTCATCATGGGAAAACACTTATTTTACTTTCGATTTTTTTTTTCCATAAAGGAAAACATCACTTCCTGAATTACTGACCCA AGCCAAACAGAAACAATAACCCTCGAGAAAATAGGTCAACAATCTGTTGTGGGGAAACCACCTCCATGTAACCCACTGGATACAGTCCCC TTAATGTTTTTGCTTCTAAATTGTACCTTTTGCTTCTGATTTCTTCTCCCCTGCTGTTTCCTGCCCATCAGAGAGGCCTGATACAAGCAA GTTTGTTTACATCCCTGGGGAATCTTTTACATCAAACTTTTGGGATCCAAATCCATCTCCTTTTAAATTTCAATCTCAGCACCTGCCAGT TATGCAAATGCCAAAATGTGGGTCATCATATAGTATATTTGAAACCTTTCTGAACATGTACACCACCCAATGCTAGAGGCTGACTTGGAA ACCGGTGGGTGCAATGCCCGAGGCTGTGGAACAATCAGCCCATCTCTTTGTGACCTGGAGCAGTCAGAGGGCCCTCAGTCACCCCGCCCC ATTCCTCACCAGAGAAAAGAATCCATTTCTATGGAAGCTCTGACGTAACTTCAGTGTTTTCTACAATACTCCTCCTGCCCCGCCCCATTA AAACAGTTCTTTTGTTAAGAAATAGCCTAATGGTCCAACTTTGCTGTCTGTTCTTCCAAATGTTTATAATACACATTATTTATAAATATG >83766_83766_11_SMAD2-C10orf90_SMAD2_chr18_45394694_ENST00000591214_C10orf90_chr10_128202508_ENST00000454341_length(amino acids)=783AA_BP=188 MSSILPFTPPVVKRLLGWKKSAGGSGGAGGGEQNGQEEKWCEKAVKSLVKKLKKTGRLDELEKAITTQNCNTKCVTIPRSLDGRLQVSHR KGLPHVIYCRLWRWPDLHSHHELKAIENCEYAFNLKKDEVCVNPYHYQRVETPVLPPVLVPRHTEILTELPPLDDYTHSIPENTNFPAGI EPQSNYIPGLRDSYHSRRDQIALKNLQSDVTEAKSDFTKETLASQNTKMISSIVISQMIDENKSRENRASLPLPCAIAQSRAHHAKQSLA NRSGVNIHRAFALLPGRLGIPAPSDERGPEAELPPKEERPCGGPRRGFASITITARRVGPPARALVWGTAGDSLCPKCRAEDTLFQAPPA LANGAHPGRHQRSFACTEFSRNSSVVRLKVPEAHTGLCERRKYWVTHADDKETSFSPDTPLSGKSPLVFSSCVHLRVSQQCPDSIYYVDK SLSVPIEPPQIASPKMHRSVLSLNLNCSSHRLTADGVDGLVNREPISEALKQELLEGDQDLVGQRWNPGLQESHLKETPSLRRVHLGTGA CPWSGSFPLENTELANVGANQVTVRKGEKDHTTHCHASDHANQLSIHIPGWSYRAGDYTCCDLVVKIKECKKSEDPTTPEPSPAAPSPAP RDGAGSPGLSEDCSESQQTPARSLTLQEALEVRKPQFISRSQERLKKLEHMVQQRKAQRKEDLRQKQSLLPIRTSKKQFTIPHPLSDNLF -------------------------------------------------------------- >83766_83766_12_SMAD2-C10orf90_SMAD2_chr18_45394694_ENST00000591214_C10orf90_chr10_128202508_ENST00000544758_length(transcript)=3038nt_BP=661nt GGAGAAGCAGCTCGCCAGCCAGCAGCCCGCCAGCCGCCGGGAGGTTCGATACAAGAGGCTGTTTTCCTAGCGTGGCTTGCTGCCTTTGGT AAGAACATGTCGTCCATCTTGCCATTCACGCCGCCAGTTGTGAAGAGACTGCTGGGATGGAAGAAGTCAGCTGGTGGGTCTGGAGGAGCA GGCGGAGGAGAGCAGAATGGGCAGGAAGAAAAGTGGTGTGAGAAAGCAGTGAAAAGTCTGGTGAAGAAGCTAAAGAAAACAGGACGATTA GATGAGCTTGAGAAAGCCATCACCACTCAAAACTGTAATACTAAATGTGTTACCATACCAAGGTCTCTTGATGGTCGTCTCCAGGTATCC CATCGAAAAGGATTGCCACATGTTATATATTGCCGATTATGGCGCTGGCCTGATCTTCACAGTCATCATGAACTCAAGGCAATTGAAAAC TGCGAATATGCTTTTAATCTTAAAAAGGATGAAGTATGTGTAAACCCTTACCACTATCAGAGAGTTGAGACACCAGTTTTGCCTCCAGTA TTAGTGCCCCGACACACCGAGATCCTAACAGAACTTCCGCCTCTGGATGACTATACTCACTCCATTCCAGAAAACACTAACTTCCCAGCA GGAATTGAGCCACAGAGTAATTATATTCCAGGATTACGGGACAGCTACCACAGTAGAAGAGATCAAATTGCCCTTAAAAATCTCCAGTCT GATGTCACAGAGGCAAAATCTGACTTCACCAAGGAGACCCTGGCATCACAAAACACAAAAATGATTTCATCCATAGTCATCTCCCAGATG ATTGATGAGAATAAGTCAAGAGAAAACAGGGCCTCCTTGCCCCTACCGTGTGCCATTGCTCAGTCTCGTGCACATCACGCCAAGCAATCT CTGGCTAACCGCAGCGGAGTCAACATTCACAGAGCATTTGCGTTACTTCCGGGCAGATTAGGAATCCCGGCACCGTCAGATGAGCGAGGA CCTGAGGCAGAGCTGCCGCCCAAAGAGGAGAGACCCTGTGGGGGCCCCCGCAGAGGGTTTGCATCCATCACCATCACGGCCAGACGCGTG GGCCCCCCAGCCCGCGCCCTGGTGTGGGGGACTGCTGGGGACTCTCTGTGCCCCAAGTGCAGGGCTGAGGACACACTGTTCCAGGCGCCC CCGGCTCTGGCCAATGGCGCCCATCCAGGTCGGCATCAGAGATCTTTTGCCTGCACAGAGTTCTCCAGAAACAGCTCCGTGGTGCGGCTG AAGGTTCCCGAGGCCCACACTGGGTTGTGTGAGAGACGCAAGTACTGGGTCACCCATGCAGACGACAAAGAGACCAGTTTTTCTCCAGAC ACCCCACTGTCAGGAAAGAGCCCGCTGGTGTTCAGTTCCTGTGTCCACCTCAGGGTGTCTCAGCAGTGTCCAGATTCAATCTATTACGTA GACAAGTCTCTCTCCGTCCCCATTGAGCCACCTCAAATTGCCAGCCCCAAAATGCACAGATCCGTCCTGTCGCTCAACCTCAATTGTAGT TCCCACAGATTAACAGCAGATGGAGTAGATGGCCTAGTGAACAGAGAGCCAATAAGCGAAGCCCTGAAGCAGGAGCTCCTGGAGGGAGAC CAGGACCTCGTAGGCCAGCGCTGGAACCCAGGTTTACAAGAAAGTCACTTGAAGGAAACCCCATCGTTGAGGCGGGTGCATTTGGGGACC GGCGCTTGTCCTTGGAGTGGTTCTTTTCCATTGGAAAACACAGAATTGGCAAATGTGGGAGCTAACCAAGTCACTGTAAGAAAAGGGGAA AAGGACCATACAACTCATTGTCACGCCAGCGATCATGCCAACCAACTGTCCATTCACATTCCTGGCTGGAGTTACAGGGCAGTACACACA AAAGTATTTTCTGGAAGCAGCAAGAGGCAACAAGGAGAAGTATGTATGACTGTGTCTGCTCCTCCAGTGGAACAGAAGCCCACTAGACAT TTCCTTCCCATTGGGGATAGCTCTCCAAGCGATGACTGTCTGTCTAGAGACCTTTCTGAGCCCACAGAGAGACGACATCAAAGCTTCCTG AAACCCAGAATCCTTTTTCCTGGGTTTCTTTGCCCCTTACAAGATGTATGTGCATCTCTGCAGGAAGACAATGGTGTTCAGATAGAAAGC AAGTTCCCCAAAGGAGATTACACATGCTGTGACTTGGTTGTAAAAATAAAGGAATGTAAGAAGAGTGAGGACCCCACCACACCTGAGCCC TCCCCAGCAGCACCCTCGCCAGCACCCCGCGATGGAGCAGGGAGCCCTGGCCTGTCCGAAGACTGTTCTGAGTCTCAGCAAACGCCTGCA AGATCTTTGACCTTGCAAGAAGCACTGGAAGTTCGTAAGCCTCAGTTCATTTCTCGCTCACAAGAACGGCTGAAGAAGCTTGAACACATG GTCCAGCAGAGGAAAGCCCAGCGGAAGGAGGACCTGAGGCAGAAGCAGAGCCTCCTTCCCATCCGCACCAGCAAGAAGCAGTTCACGATT CCCCATCCTCTGAGTGATAACTTGTTCAAACCCAAAGAACGGTGCATTTCAGAGAAGGAGATGCATATGCGATCTAAGAGAATCTATGAT AACTTGCCGGAAGTTAAAAAGAAAAAAGAAGAACAAAGGAAAAGGGTGATCTTACAAAGTAACAGACTCCGTGCCGAAGTCTTCAAAAAG CAATTACTGGACCAGCTCCTTCAAAGGAATGCGGTCTAACCACAGGCTGCCCTGCTGACCACACTACCTGGACCTGGGAGGACTTCGAAT GCTGGATAAGCCATTAAACTTAGCATTATCTTCATCATGGGAAAACACTTATTTTACTTTCGATTTTTTTTTTCCATAAAGGAAAACATC ACTTCCTGAATTACTGACCCAAGCCAAACAGAAACAATAACCCTCGAGAAAATAGGTCAACAATCTGTTGTGGGGAAACCACCTCCATGT >83766_83766_12_SMAD2-C10orf90_SMAD2_chr18_45394694_ENST00000591214_C10orf90_chr10_128202508_ENST00000544758_length(amino acids)=880AA_BP=188 MSSILPFTPPVVKRLLGWKKSAGGSGGAGGGEQNGQEEKWCEKAVKSLVKKLKKTGRLDELEKAITTQNCNTKCVTIPRSLDGRLQVSHR KGLPHVIYCRLWRWPDLHSHHELKAIENCEYAFNLKKDEVCVNPYHYQRVETPVLPPVLVPRHTEILTELPPLDDYTHSIPENTNFPAGI EPQSNYIPGLRDSYHSRRDQIALKNLQSDVTEAKSDFTKETLASQNTKMISSIVISQMIDENKSRENRASLPLPCAIAQSRAHHAKQSLA NRSGVNIHRAFALLPGRLGIPAPSDERGPEAELPPKEERPCGGPRRGFASITITARRVGPPARALVWGTAGDSLCPKCRAEDTLFQAPPA LANGAHPGRHQRSFACTEFSRNSSVVRLKVPEAHTGLCERRKYWVTHADDKETSFSPDTPLSGKSPLVFSSCVHLRVSQQCPDSIYYVDK SLSVPIEPPQIASPKMHRSVLSLNLNCSSHRLTADGVDGLVNREPISEALKQELLEGDQDLVGQRWNPGLQESHLKETPSLRRVHLGTGA CPWSGSFPLENTELANVGANQVTVRKGEKDHTTHCHASDHANQLSIHIPGWSYRAVHTKVFSGSSKRQQGEVCMTVSAPPVEQKPTRHFL PIGDSSPSDDCLSRDLSEPTERRHQSFLKPRILFPGFLCPLQDVCASLQEDNGVQIESKFPKGDYTCCDLVVKIKECKKSEDPTTPEPSP AAPSPAPRDGAGSPGLSEDCSESQQTPARSLTLQEALEVRKPQFISRSQERLKKLEHMVQQRKAQRKEDLRQKQSLLPIRTSKKQFTIPH -------------------------------------------------------------- |
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Fusion Gene PPI Analysis for SMAD2-C10orf90 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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Related Drugs for SMAD2-C10orf90 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.8 2021-05-08) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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Related Diseases for SMAD2-C10orf90 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
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