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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:SMARCA2-BEND2 (FusionGDB2 ID:83869)

Fusion Gene Summary for SMARCA2-BEND2

check button Fusion gene summary
Fusion gene informationFusion gene name: SMARCA2-BEND2
Fusion gene ID: 83869
HgeneTgene
Gene symbol

SMARCA2

BEND2

Gene ID

6595

139105

Gene nameSWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2BEN domain containing 2
SynonymsBAF190|BRM|NCBRS|SNF2|SNF2L2|SNF2LA|SWI2|Sth1p|hBRM|hSNF2aCXorf20
Cytomap

9p24.3

Xp22.13

Type of geneprotein-codingprotein-coding
Descriptionprobable global transcription activator SNF2L2ATP-dependent helicase SMARCA2BAF190BBRG1-associated factor 190BSNF2-alphaSNF2/SWI2-like protein 2SWI/SNF-related matrix-associated actin-dependent regulator of chromatin a2brahma homologglobal transcrBEN domain-containing protein 2
Modification date2020031520200313
UniProtAcc.

Q8NDZ0

Ensembl transtripts involved in fusion geneENST00000349721, ENST00000357248, 
ENST00000382194, ENST00000382203, 
ENST00000302401, ENST00000324954, 
ENST00000382185, ENST00000382186, 
ENST00000491574, 		ENST00000380030, 
ENST00000380033, 
Fusion gene scores* DoF score14 X 9 X 10=12602 X 2 X 2=8
# samples 152
** MAII scorelog2(15/1260*10)=-3.0703893278914
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(2/8*10)=1.32192809488736
Context

PubMed: SMARCA2 [Title/Abstract] AND BEND2 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointSMARCA2(2039900)-BEND2(18213562), # samples:4
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneSMARCA2

GO:0008285

negative regulation of cell proliferation

14660596

HgeneSMARCA2

GO:0045892

negative regulation of transcription, DNA-templated

12065415

HgeneSMARCA2

GO:0045893

positive regulation of transcription, DNA-templated

17984088

HgeneSMARCA2

GO:0045944

positive regulation of transcription by RNA polymerase II

15774904


check buttonFusion gene breakpoints across SMARCA2 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across BEND2 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4PAADTCGA-3A-A9IR-01ASMARCA2chr9

2039900

-BEND2chrX

18213562

-
ChimerDB4PAADTCGA-3A-A9IR-01ASMARCA2chr9

2039900

+BEND2chrX

18213562

-
ChimerDB4PAADTCGA-3A-A9IRSMARCA2chr9

2039900

+BEND2chrX

18213562

-


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Fusion Gene ORF analysis for SMARCA2-BEND2

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000349721ENST00000380030SMARCA2chr9

2039900

+BEND2chrX

18213562

-
5CDS-intronENST00000357248ENST00000380030SMARCA2chr9

2039900

+BEND2chrX

18213562

-
5CDS-intronENST00000382194ENST00000380030SMARCA2chr9

2039900

+BEND2chrX

18213562

-
5CDS-intronENST00000382203ENST00000380030SMARCA2chr9

2039900

+BEND2chrX

18213562

-
In-frameENST00000349721ENST00000380033SMARCA2chr9

2039900

+BEND2chrX

18213562

-
In-frameENST00000357248ENST00000380033SMARCA2chr9

2039900

+BEND2chrX

18213562

-
In-frameENST00000382194ENST00000380033SMARCA2chr9

2039900

+BEND2chrX

18213562

-
In-frameENST00000382203ENST00000380033SMARCA2chr9

2039900

+BEND2chrX

18213562

-
intron-3CDSENST00000302401ENST00000380033SMARCA2chr9

2039900

+BEND2chrX

18213562

-
intron-3CDSENST00000324954ENST00000380033SMARCA2chr9

2039900

+BEND2chrX

18213562

-
intron-3CDSENST00000382185ENST00000380033SMARCA2chr9

2039900

+BEND2chrX

18213562

-
intron-3CDSENST00000382186ENST00000380033SMARCA2chr9

2039900

+BEND2chrX

18213562

-
intron-3CDSENST00000491574ENST00000380033SMARCA2chr9

2039900

+BEND2chrX

18213562

-
intron-intronENST00000302401ENST00000380030SMARCA2chr9

2039900

+BEND2chrX

18213562

-
intron-intronENST00000324954ENST00000380030SMARCA2chr9

2039900

+BEND2chrX

18213562

-
intron-intronENST00000382185ENST00000380030SMARCA2chr9

2039900

+BEND2chrX

18213562

-
intron-intronENST00000382186ENST00000380030SMARCA2chr9

2039900

+BEND2chrX

18213562

-
intron-intronENST00000491574ENST00000380030SMARCA2chr9

2039900

+BEND2chrX

18213562

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000357248SMARCA2chr92039900+ENST00000380033BEND2chrX18213562-4334889992255718
ENST00000349721SMARCA2chr92039900+ENST00000380033BEND2chrX18213562-4334889992255718
ENST00000382203SMARCA2chr92039900+ENST00000380033BEND2chrX18213562-44449992092365718
ENST00000382194SMARCA2chr92039900+ENST00000380033BEND2chrX18213562-423979442160718

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000357248ENST00000380033SMARCA2chr92039900+BEND2chrX18213562-0.0004534320.9995466
ENST00000349721ENST00000380033SMARCA2chr92039900+BEND2chrX18213562-0.0004534320.9995466
ENST00000382203ENST00000380033SMARCA2chr92039900+BEND2chrX18213562-0.0004471530.9995528
ENST00000382194ENST00000380033SMARCA2chr92039900+BEND2chrX18213562-0.0004306690.99956936

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Fusion Genomic Features for SMARCA2-BEND2


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for SMARCA2-BEND2


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr9:2039900/chrX:18213562)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
.BEND2

Q8NDZ0

FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneSMARCA2chr9:2039900chrX:18213562ENST00000349721+434216_2382631591.0Compositional biasNote=Poly-Gln
HgeneSMARCA2chr9:2039900chrX:18213562ENST00000349721+434245_2532631591.0Compositional biasNote=Poly-Gln
HgeneSMARCA2chr9:2039900chrX:18213562ENST00000357248+433216_2382631573.0Compositional biasNote=Poly-Gln
HgeneSMARCA2chr9:2039900chrX:18213562ENST00000357248+433245_2532631573.0Compositional biasNote=Poly-Gln
HgeneSMARCA2chr9:2039900chrX:18213562ENST00000382194+332216_2382631573.0Compositional biasNote=Poly-Gln
HgeneSMARCA2chr9:2039900chrX:18213562ENST00000382194+332245_2532631573.0Compositional biasNote=Poly-Gln
HgeneSMARCA2chr9:2039900chrX:18213562ENST00000382203+434216_2382631591.0Compositional biasNote=Poly-Gln
HgeneSMARCA2chr9:2039900chrX:18213562ENST00000382203+434245_2532631591.0Compositional biasNote=Poly-Gln
HgeneSMARCA2chr9:2039900chrX:18213562ENST00000349721+434173_2082631591.0DomainQLQ
HgeneSMARCA2chr9:2039900chrX:18213562ENST00000357248+433173_2082631573.0DomainQLQ
HgeneSMARCA2chr9:2039900chrX:18213562ENST00000382194+332173_2082631573.0DomainQLQ
HgeneSMARCA2chr9:2039900chrX:18213562ENST00000382203+434173_2082631591.0DomainQLQ
TgeneBEND2chr9:2039900chrX:18213562ENST00000380030011483_5820646.0DomainBEN 1
TgeneBEND2chr9:2039900chrX:18213562ENST00000380030011667_7650646.0DomainBEN 2
TgeneBEND2chr9:2039900chrX:18213562ENST00000380033514483_582344800.0DomainBEN 1
TgeneBEND2chr9:2039900chrX:18213562ENST00000380033514667_765344800.0DomainBEN 2

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneSMARCA2chr9:2039900chrX:18213562ENST00000349721+4341297_13012631591.0Compositional biasNote=Poly-Glu
HgeneSMARCA2chr9:2039900chrX:18213562ENST00000349721+4341518_15292631591.0Compositional biasNote=Poly-Glu
HgeneSMARCA2chr9:2039900chrX:18213562ENST00000349721+434559_5622631591.0Compositional biasNote=Poly-Arg
HgeneSMARCA2chr9:2039900chrX:18213562ENST00000349721+434643_6502631591.0Compositional biasNote=Poly-Glu
HgeneSMARCA2chr9:2039900chrX:18213562ENST00000357248+4331297_13012631573.0Compositional biasNote=Poly-Glu
HgeneSMARCA2chr9:2039900chrX:18213562ENST00000357248+4331518_15292631573.0Compositional biasNote=Poly-Glu
HgeneSMARCA2chr9:2039900chrX:18213562ENST00000357248+433559_5622631573.0Compositional biasNote=Poly-Arg
HgeneSMARCA2chr9:2039900chrX:18213562ENST00000357248+433643_6502631573.0Compositional biasNote=Poly-Glu
HgeneSMARCA2chr9:2039900chrX:18213562ENST00000382194+3321297_13012631573.0Compositional biasNote=Poly-Glu
HgeneSMARCA2chr9:2039900chrX:18213562ENST00000382194+3321518_15292631573.0Compositional biasNote=Poly-Glu
HgeneSMARCA2chr9:2039900chrX:18213562ENST00000382194+332559_5622631573.0Compositional biasNote=Poly-Arg
HgeneSMARCA2chr9:2039900chrX:18213562ENST00000382194+332643_6502631573.0Compositional biasNote=Poly-Glu
HgeneSMARCA2chr9:2039900chrX:18213562ENST00000382203+4341297_13012631591.0Compositional biasNote=Poly-Glu
HgeneSMARCA2chr9:2039900chrX:18213562ENST00000382203+4341518_15292631591.0Compositional biasNote=Poly-Glu
HgeneSMARCA2chr9:2039900chrX:18213562ENST00000382203+434559_5622631591.0Compositional biasNote=Poly-Arg
HgeneSMARCA2chr9:2039900chrX:18213562ENST00000382203+434643_6502631591.0Compositional biasNote=Poly-Glu
HgeneSMARCA2chr9:2039900chrX:18213562ENST00000349721+4341054_12162631591.0DomainHelicase C-terminal
HgeneSMARCA2chr9:2039900chrX:18213562ENST00000349721+4341419_14892631591.0DomainBromo
HgeneSMARCA2chr9:2039900chrX:18213562ENST00000349721+434436_5082631591.0DomainHSA
HgeneSMARCA2chr9:2039900chrX:18213562ENST00000349721+434736_9012631591.0DomainHelicase ATP-binding
HgeneSMARCA2chr9:2039900chrX:18213562ENST00000357248+4331054_12162631573.0DomainHelicase C-terminal
HgeneSMARCA2chr9:2039900chrX:18213562ENST00000357248+4331419_14892631573.0DomainBromo
HgeneSMARCA2chr9:2039900chrX:18213562ENST00000357248+433436_5082631573.0DomainHSA
HgeneSMARCA2chr9:2039900chrX:18213562ENST00000357248+433736_9012631573.0DomainHelicase ATP-binding
HgeneSMARCA2chr9:2039900chrX:18213562ENST00000382194+3321054_12162631573.0DomainHelicase C-terminal
HgeneSMARCA2chr9:2039900chrX:18213562ENST00000382194+3321419_14892631573.0DomainBromo
HgeneSMARCA2chr9:2039900chrX:18213562ENST00000382194+332436_5082631573.0DomainHSA
HgeneSMARCA2chr9:2039900chrX:18213562ENST00000382194+332736_9012631573.0DomainHelicase ATP-binding
HgeneSMARCA2chr9:2039900chrX:18213562ENST00000382203+4341054_12162631591.0DomainHelicase C-terminal
HgeneSMARCA2chr9:2039900chrX:18213562ENST00000382203+4341419_14892631591.0DomainBromo
HgeneSMARCA2chr9:2039900chrX:18213562ENST00000382203+434436_5082631591.0DomainHSA
HgeneSMARCA2chr9:2039900chrX:18213562ENST00000382203+434736_9012631591.0DomainHelicase ATP-binding
HgeneSMARCA2chr9:2039900chrX:18213562ENST00000349721+434851_8542631591.0MotifNote=DEGH box
HgeneSMARCA2chr9:2039900chrX:18213562ENST00000357248+433851_8542631573.0MotifNote=DEGH box
HgeneSMARCA2chr9:2039900chrX:18213562ENST00000382194+332851_8542631573.0MotifNote=DEGH box
HgeneSMARCA2chr9:2039900chrX:18213562ENST00000382203+434851_8542631591.0MotifNote=DEGH box
HgeneSMARCA2chr9:2039900chrX:18213562ENST00000349721+434749_7562631591.0Nucleotide bindingATP
HgeneSMARCA2chr9:2039900chrX:18213562ENST00000357248+433749_7562631573.0Nucleotide bindingATP
HgeneSMARCA2chr9:2039900chrX:18213562ENST00000382194+332749_7562631573.0Nucleotide bindingATP
HgeneSMARCA2chr9:2039900chrX:18213562ENST00000382203+434749_7562631591.0Nucleotide bindingATP


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Fusion Gene Sequence for SMARCA2-BEND2


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>83869_83869_1_SMARCA2-BEND2_SMARCA2_chr9_2039900_ENST00000349721_BEND2_chrX_18213562_ENST00000380033_length(transcript)=4334nt_BP=889nt
TTTCTGTACTCTGGGTGACTCAGAGAGGGAAGAGATTCAGCCAGCACACTCCTCGCGAGCAAGCATTACTCTACTGACTGGCAGAGACAG
GAGAGGTAGATGTCCACGCCCACAGACCCTGGTGCGATGCCCCACCCAGGGCCTTCGCCGGGGCCTGGGCCTTCCCCTGGGCCAATTCTT
GGGCCTAGTCCAGGACCAGGACCATCCCCAGGTTCCGTCCACAGCATGATGGGGCCAAGTCCTGGACCTCCAAGTGTCTCCCATCCTATG
CCGACGATGGGGTCCACAGACTTCCCACAGGAAGGCATGCATCAAATGCATAAGCCCATCGATGGTATACATGACAAGGGGATTGTAGAA
GACATCCATTGTGGATCCATGAAGGGCACTGGTATGCGACCACCTCACCCAGGCATGGGCCCTCCCCAGAGTCCAATGGATCAACACAGC
CAAGGTTATATGTCACCACACCCATCTCCATTAGGAGCCCCAGAGCACGTCTCCAGCCCTATGTCTGGAGGAGGCCCAACTCCACCTCAG
ATGCCACCAAGCCAGCCGGGGGCCCTCATCCCAGGTGATCCGCAGGCCATGAGCCAGCCCAACAGAGGTCCCTCACCTTTCAGTCCTGTC
CAGCTGCATCAGCTTCGAGCTCAGATTTTAGCTTATAAAATGCTGGCCCGAGGCCAGCCCCTCCCCGAAACGCTGCAGCTTGCAGTCCAG
GGGAAAAGGACGTTGCCTGGCTTGCAGCAACAACAGCAGCAGCAACAGCAGCAGCAGCAGCAGCAGCAGCAGCAGCAGCAGCAGCAACAG
CAGCCGCAGCAGCAGCCGCCGCAACCACAGACGCAGCAACAACAGCAGCCGGCCCTTGTTAACTACAACAGACCATCTGCTGAGAAAATT
ATACTTACTGAAATGCCAGGAACAACAGAAACCAACGTGGAAAATAACTCTCAGACAGTGTATTACCCAGCTTTATCGGGAAATACGAGT
GCCCCATATCCAGCCTCTTCATATCTTCCCATCACTTCTAATTTTGAATCTGGCCCACAAATGAGTTATGGGACAATGAGTTACTCAACT
GAAATGAAAAATAACTGTGACCAAGATGATGCTTCAGCATCTGCCTGCCTCACTCCCGATTTTGCACTGTTACCTCTGAATATTTTGGTA
AAAGTAGACACCAACACGGAAAACAGCGTCAACACAATGAATCGCTCAACTTTATTGGACAGTGACAGTGGCCAGGATTCTTCCTCATCA
TCTGTCTGTATCCCTCCCAAGTATGGCTATCTTGGTGATCCAAAAAGAAATGTCAGAGTACTTAAAATCCATTTGCTGGCCGTACAAAAT
ATGGCCAAACCTAAGCAAGCAGCCTGCTACTTGGTTCGTATTTTGTTCTCCAAGGAAATCCTGATTAGCAGCTCAGTGGATATCCATTTG
AAAGACAGCCAATCCCTCGACCCGAACAAAATGGCTGCATTGAGAGAATATCTGGCAACAACTTTTCCCACCTGTGATTTGCATGAACAT
GGAAAAGACTGGCAGGACTGTATTTCTGGTATCAATTCTATGATCTACTGTTTATGTTCTGAAGGCAAGAGTACTCCAAAAACTGTTCGC
AAAAATAAAAAACGTACCAACCGTGTTGCATCGGCATCTGCAGATAGAAATGACCAAAGGGGCAGAGATGGTGGTGAAGGCTGTTCTTGG
ATGTTTCAGCCAATGAATAACTCCAAAATGAGAGAAAAGAGGAACTTGCAGCCAAACAGTAATGCTATCCCTGAAGGAATGCGAGAACCT
TCCACTGATAATCCAGAGGAACCTGGTGAAGCATGGAGCTATTTTGGAAGACCATGGAGAAATATACGGATGCCATGTTCAGTACTGACT
TTGGCAAAAACTAAGTCTTGCGCAAGCCTGTCGGCTAGATACCTTATTCAGAAACTCTTCACAAAAGATGTCCTGGTCCAAAGTAACGTC
TATGGCAATCTGAAGCATGGCCTGTGTGCCCTTGACCCCAATAAGATTAGTGCTCTCCGAGAGTTCCTCCAAGAAAACTACCCAATTTGT
GATCTCTCGGAAAATGGAAGAGACTGGAAGTCGTGTGTGACCTCCATCAACAGCGGTATCCGTAGCCTTAGACATGACGTCAGAAGGGCT
GAAGCCAGGTCTCAGTCGCTTCCAGCAGTGACCCCTCCAGAGCTGGAGCAGGAGTCAAAGCCAGGAGATCCCGACGCCACTGACCCAAGC
ACCTGAACGGCAGCTGCCAAACTTTTTTTTTTTTTTTAACTGTTAAGACTATTTTGTAAGTTTCTCAAGTTCTAATTCCAAAATCAGCCT
GCTGTACTGGCAGAGTAGTTTGCATTGACACCTGTAGTAATCGCCAAACCTCTTTTTCTGCTCATAAAGGAGGTAGAATCACATTAGGAA
GATACGTAATGTTTCATCTGTGGATTTGATGACAACCTCTGATTGAGGGAATGGTAGTAAACTCCTCATGGGCTTGTGACCCATGGCTTT
GACTTAGATAATTGACATTAATATACTTTGTTTTTTTGATAAGGTAGAGAAAGAAATTCAATAGAAAGTAAGGAGCCACTCAGTCAAATA
ATATAATTCGTATAAAACTTGACAAGTCTTTTTATTTTTGTGACTTGTGAGATAGTTTAAGATATTTTTATGTGACCAATTTGTAGAATG
AATACATATTTTCAAAGTTATCTTTTCAAAATTCAACTTTTAGAGTATTTTAGCAAAATATATGTATAGTTTATAATATAGAAGTATAGC
TTTATAAAGATATTAAGGATTTATTTTTTAAAATAATTCTCTGAATAGTTTGCTGTAGTAGTTGCCTTCAGCTTAATAAAACCATAGTAC
TTCTACATACATCTTTATAAGTTAGGCTATGCCTACAAAGGTCTTAAAAAGTAGATAATTTACCGGGTGTAGTGGCTCACACCTGTAATC
CCAGCACTTTGGGAGGCCGAGACGGGTGGATCACCTGAGGTCAGGGGTTCGAGACCAGCCTGGCCAACATGACGAAACCCCATCTCTACT
AAAAATACAAAAAAAGTAGCCAGGCATGGTGGCAAGCACCTGTAGTCCCAGTTACTCGGGTGGCTGAGGCAGGAGAATCACTTGAACCTG
GGAGGTGGAGACTGCAGTGAGCCGAGATTGTGCCACTGCACTCGAGCCTGGGTGACAGAGTGAGACTCCGTCTCGGGAAAAGAAAAAAAA
GAAGTAGATAATTAAAAAAATCTTGCATAAAAAAAAATCTTCCATAAAGGGCAAAAAGGCTTTAACTTCCATTATTCAGATTTAATCCAA
CTAAGATAGTCTTTGGCTTCATTCACTGTTCAGTTTCACAAGTTTTTTACAACTACTAGTAACAGAGCTAATACAGAATAGTAATCCACA
TTATAAACATAGATCAAAATACCACATCATACCCCATAAATACATGCAGTTATTATTTGTCAATTAAAAATAAAATTTTTTTAAAAGAAA
AGTACAGTTCGACCCTAGGCAAGAAGAAATTTCAAATTGTATATGCATATTTTGAATTTGGTTTATATTTTGTGGTATCTGAAATATTCC
CTGGACTAGAAGCAAAACCACAGAAACAAAACTTTACATTTAGAAAAAAATTTCAAGACTTCTATTGCTAACTTTATTACATTAGTGGTT
TTTAGAAGTTATTTAGAGCAGTCTTGTCTGATAGAACTTTCCACCATGATGGAAATGTAAATAAATATACCACATTAAAAATATAAATTT
GCAATGTCCAATAGGCTCGTATGGCTATTGAGCATTTAAGATGTAATTAATTAGACAGAGGAAGTAAATTTAACATTTTCTCTCATTTTA
GCTAATTAGAATTTAAAGTGAAATAGCCACAAGTGGATAGTGGCTACTGTGTTGGATGGCACAGTTCAAAATGCCTCTTATTTATAAAAA
AAAGTGTTTAAAAGTGGTTCCCATGGCTTGAAGAGGAATAATATACACATAACTTCTTTAAAATCACATTTTGTTTGAGATGGAGATCTT
GCTATATTGCCCAGGCTTATCTGGAACTCCTGGGCTCAAGAGGGAGGATCACATTTGACTGGACAAAATACATTTTATAAAGGTGTTTTG
TATTTTATGTTAAAGTGGAATTGTGTCTTCAAAATTGTGTCTTCAAAATTTCACAAGTTAATACTATTACTGTATTAGTCCAATGTTAAA
CATTTTAAATGCCTGCTCATAAGACTCATTTTTGATAAATAAATGTATCTTTAATGTTTTGTTTCCCAAATAGATACAATAAATAAACAT

>83869_83869_1_SMARCA2-BEND2_SMARCA2_chr9_2039900_ENST00000349721_BEND2_chrX_18213562_ENST00000380033_length(amino acids)=718AA_BP=261
MSTPTDPGAMPHPGPSPGPGPSPGPILGPSPGPGPSPGSVHSMMGPSPGPPSVSHPMPTMGSTDFPQEGMHQMHKPIDGIHDKGIVEDIH
CGSMKGTGMRPPHPGMGPPQSPMDQHSQGYMSPHPSPLGAPEHVSSPMSGGGPTPPQMPPSQPGALIPGDPQAMSQPNRGPSPFSPVQLH
QLRAQILAYKMLARGQPLPETLQLAVQGKRTLPGLQQQQQQQQQQQQQQQQQQQQQQQPQQQPPQPQTQQQQQPALVNYNRPSAEKIILT
EMPGTTETNVENNSQTVYYPALSGNTSAPYPASSYLPITSNFESGPQMSYGTMSYSTEMKNNCDQDDASASACLTPDFALLPLNILVKVD
TNTENSVNTMNRSTLLDSDSGQDSSSSSVCIPPKYGYLGDPKRNVRVLKIHLLAVQNMAKPKQAACYLVRILFSKEILISSSVDIHLKDS
QSLDPNKMAALREYLATTFPTCDLHEHGKDWQDCISGINSMIYCLCSEGKSTPKTVRKNKKRTNRVASASADRNDQRGRDGGEGCSWMFQ
PMNNSKMREKRNLQPNSNAIPEGMREPSTDNPEEPGEAWSYFGRPWRNIRMPCSVLTLAKTKSCASLSARYLIQKLFTKDVLVQSNVYGN

--------------------------------------------------------------
>83869_83869_2_SMARCA2-BEND2_SMARCA2_chr9_2039900_ENST00000357248_BEND2_chrX_18213562_ENST00000380033_length(transcript)=4334nt_BP=889nt
TTTCTGTACTCTGGGTGACTCAGAGAGGGAAGAGATTCAGCCAGCACACTCCTCGCGAGCAAGCATTACTCTACTGACTGGCAGAGACAG
GAGAGGTAGATGTCCACGCCCACAGACCCTGGTGCGATGCCCCACCCAGGGCCTTCGCCGGGGCCTGGGCCTTCCCCTGGGCCAATTCTT
GGGCCTAGTCCAGGACCAGGACCATCCCCAGGTTCCGTCCACAGCATGATGGGGCCAAGTCCTGGACCTCCAAGTGTCTCCCATCCTATG
CCGACGATGGGGTCCACAGACTTCCCACAGGAAGGCATGCATCAAATGCATAAGCCCATCGATGGTATACATGACAAGGGGATTGTAGAA
GACATCCATTGTGGATCCATGAAGGGCACTGGTATGCGACCACCTCACCCAGGCATGGGCCCTCCCCAGAGTCCAATGGATCAACACAGC
CAAGGTTATATGTCACCACACCCATCTCCATTAGGAGCCCCAGAGCACGTCTCCAGCCCTATGTCTGGAGGAGGCCCAACTCCACCTCAG
ATGCCACCAAGCCAGCCGGGGGCCCTCATCCCAGGTGATCCGCAGGCCATGAGCCAGCCCAACAGAGGTCCCTCACCTTTCAGTCCTGTC
CAGCTGCATCAGCTTCGAGCTCAGATTTTAGCTTATAAAATGCTGGCCCGAGGCCAGCCCCTCCCCGAAACGCTGCAGCTTGCAGTCCAG
GGGAAAAGGACGTTGCCTGGCTTGCAGCAACAACAGCAGCAGCAACAGCAGCAGCAGCAGCAGCAGCAGCAGCAGCAGCAGCAGCAACAG
CAGCCGCAGCAGCAGCCGCCGCAACCACAGACGCAGCAACAACAGCAGCCGGCCCTTGTTAACTACAACAGACCATCTGCTGAGAAAATT
ATACTTACTGAAATGCCAGGAACAACAGAAACCAACGTGGAAAATAACTCTCAGACAGTGTATTACCCAGCTTTATCGGGAAATACGAGT
GCCCCATATCCAGCCTCTTCATATCTTCCCATCACTTCTAATTTTGAATCTGGCCCACAAATGAGTTATGGGACAATGAGTTACTCAACT
GAAATGAAAAATAACTGTGACCAAGATGATGCTTCAGCATCTGCCTGCCTCACTCCCGATTTTGCACTGTTACCTCTGAATATTTTGGTA
AAAGTAGACACCAACACGGAAAACAGCGTCAACACAATGAATCGCTCAACTTTATTGGACAGTGACAGTGGCCAGGATTCTTCCTCATCA
TCTGTCTGTATCCCTCCCAAGTATGGCTATCTTGGTGATCCAAAAAGAAATGTCAGAGTACTTAAAATCCATTTGCTGGCCGTACAAAAT
ATGGCCAAACCTAAGCAAGCAGCCTGCTACTTGGTTCGTATTTTGTTCTCCAAGGAAATCCTGATTAGCAGCTCAGTGGATATCCATTTG
AAAGACAGCCAATCCCTCGACCCGAACAAAATGGCTGCATTGAGAGAATATCTGGCAACAACTTTTCCCACCTGTGATTTGCATGAACAT
GGAAAAGACTGGCAGGACTGTATTTCTGGTATCAATTCTATGATCTACTGTTTATGTTCTGAAGGCAAGAGTACTCCAAAAACTGTTCGC
AAAAATAAAAAACGTACCAACCGTGTTGCATCGGCATCTGCAGATAGAAATGACCAAAGGGGCAGAGATGGTGGTGAAGGCTGTTCTTGG
ATGTTTCAGCCAATGAATAACTCCAAAATGAGAGAAAAGAGGAACTTGCAGCCAAACAGTAATGCTATCCCTGAAGGAATGCGAGAACCT
TCCACTGATAATCCAGAGGAACCTGGTGAAGCATGGAGCTATTTTGGAAGACCATGGAGAAATATACGGATGCCATGTTCAGTACTGACT
TTGGCAAAAACTAAGTCTTGCGCAAGCCTGTCGGCTAGATACCTTATTCAGAAACTCTTCACAAAAGATGTCCTGGTCCAAAGTAACGTC
TATGGCAATCTGAAGCATGGCCTGTGTGCCCTTGACCCCAATAAGATTAGTGCTCTCCGAGAGTTCCTCCAAGAAAACTACCCAATTTGT
GATCTCTCGGAAAATGGAAGAGACTGGAAGTCGTGTGTGACCTCCATCAACAGCGGTATCCGTAGCCTTAGACATGACGTCAGAAGGGCT
GAAGCCAGGTCTCAGTCGCTTCCAGCAGTGACCCCTCCAGAGCTGGAGCAGGAGTCAAAGCCAGGAGATCCCGACGCCACTGACCCAAGC
ACCTGAACGGCAGCTGCCAAACTTTTTTTTTTTTTTTAACTGTTAAGACTATTTTGTAAGTTTCTCAAGTTCTAATTCCAAAATCAGCCT
GCTGTACTGGCAGAGTAGTTTGCATTGACACCTGTAGTAATCGCCAAACCTCTTTTTCTGCTCATAAAGGAGGTAGAATCACATTAGGAA
GATACGTAATGTTTCATCTGTGGATTTGATGACAACCTCTGATTGAGGGAATGGTAGTAAACTCCTCATGGGCTTGTGACCCATGGCTTT
GACTTAGATAATTGACATTAATATACTTTGTTTTTTTGATAAGGTAGAGAAAGAAATTCAATAGAAAGTAAGGAGCCACTCAGTCAAATA
ATATAATTCGTATAAAACTTGACAAGTCTTTTTATTTTTGTGACTTGTGAGATAGTTTAAGATATTTTTATGTGACCAATTTGTAGAATG
AATACATATTTTCAAAGTTATCTTTTCAAAATTCAACTTTTAGAGTATTTTAGCAAAATATATGTATAGTTTATAATATAGAAGTATAGC
TTTATAAAGATATTAAGGATTTATTTTTTAAAATAATTCTCTGAATAGTTTGCTGTAGTAGTTGCCTTCAGCTTAATAAAACCATAGTAC
TTCTACATACATCTTTATAAGTTAGGCTATGCCTACAAAGGTCTTAAAAAGTAGATAATTTACCGGGTGTAGTGGCTCACACCTGTAATC
CCAGCACTTTGGGAGGCCGAGACGGGTGGATCACCTGAGGTCAGGGGTTCGAGACCAGCCTGGCCAACATGACGAAACCCCATCTCTACT
AAAAATACAAAAAAAGTAGCCAGGCATGGTGGCAAGCACCTGTAGTCCCAGTTACTCGGGTGGCTGAGGCAGGAGAATCACTTGAACCTG
GGAGGTGGAGACTGCAGTGAGCCGAGATTGTGCCACTGCACTCGAGCCTGGGTGACAGAGTGAGACTCCGTCTCGGGAAAAGAAAAAAAA
GAAGTAGATAATTAAAAAAATCTTGCATAAAAAAAAATCTTCCATAAAGGGCAAAAAGGCTTTAACTTCCATTATTCAGATTTAATCCAA
CTAAGATAGTCTTTGGCTTCATTCACTGTTCAGTTTCACAAGTTTTTTACAACTACTAGTAACAGAGCTAATACAGAATAGTAATCCACA
TTATAAACATAGATCAAAATACCACATCATACCCCATAAATACATGCAGTTATTATTTGTCAATTAAAAATAAAATTTTTTTAAAAGAAA
AGTACAGTTCGACCCTAGGCAAGAAGAAATTTCAAATTGTATATGCATATTTTGAATTTGGTTTATATTTTGTGGTATCTGAAATATTCC
CTGGACTAGAAGCAAAACCACAGAAACAAAACTTTACATTTAGAAAAAAATTTCAAGACTTCTATTGCTAACTTTATTACATTAGTGGTT
TTTAGAAGTTATTTAGAGCAGTCTTGTCTGATAGAACTTTCCACCATGATGGAAATGTAAATAAATATACCACATTAAAAATATAAATTT
GCAATGTCCAATAGGCTCGTATGGCTATTGAGCATTTAAGATGTAATTAATTAGACAGAGGAAGTAAATTTAACATTTTCTCTCATTTTA
GCTAATTAGAATTTAAAGTGAAATAGCCACAAGTGGATAGTGGCTACTGTGTTGGATGGCACAGTTCAAAATGCCTCTTATTTATAAAAA
AAAGTGTTTAAAAGTGGTTCCCATGGCTTGAAGAGGAATAATATACACATAACTTCTTTAAAATCACATTTTGTTTGAGATGGAGATCTT
GCTATATTGCCCAGGCTTATCTGGAACTCCTGGGCTCAAGAGGGAGGATCACATTTGACTGGACAAAATACATTTTATAAAGGTGTTTTG
TATTTTATGTTAAAGTGGAATTGTGTCTTCAAAATTGTGTCTTCAAAATTTCACAAGTTAATACTATTACTGTATTAGTCCAATGTTAAA
CATTTTAAATGCCTGCTCATAAGACTCATTTTTGATAAATAAATGTATCTTTAATGTTTTGTTTCCCAAATAGATACAATAAATAAACAT

>83869_83869_2_SMARCA2-BEND2_SMARCA2_chr9_2039900_ENST00000357248_BEND2_chrX_18213562_ENST00000380033_length(amino acids)=718AA_BP=261
MSTPTDPGAMPHPGPSPGPGPSPGPILGPSPGPGPSPGSVHSMMGPSPGPPSVSHPMPTMGSTDFPQEGMHQMHKPIDGIHDKGIVEDIH
CGSMKGTGMRPPHPGMGPPQSPMDQHSQGYMSPHPSPLGAPEHVSSPMSGGGPTPPQMPPSQPGALIPGDPQAMSQPNRGPSPFSPVQLH
QLRAQILAYKMLARGQPLPETLQLAVQGKRTLPGLQQQQQQQQQQQQQQQQQQQQQQQPQQQPPQPQTQQQQQPALVNYNRPSAEKIILT
EMPGTTETNVENNSQTVYYPALSGNTSAPYPASSYLPITSNFESGPQMSYGTMSYSTEMKNNCDQDDASASACLTPDFALLPLNILVKVD
TNTENSVNTMNRSTLLDSDSGQDSSSSSVCIPPKYGYLGDPKRNVRVLKIHLLAVQNMAKPKQAACYLVRILFSKEILISSSVDIHLKDS
QSLDPNKMAALREYLATTFPTCDLHEHGKDWQDCISGINSMIYCLCSEGKSTPKTVRKNKKRTNRVASASADRNDQRGRDGGEGCSWMFQ
PMNNSKMREKRNLQPNSNAIPEGMREPSTDNPEEPGEAWSYFGRPWRNIRMPCSVLTLAKTKSCASLSARYLIQKLFTKDVLVQSNVYGN

--------------------------------------------------------------
>83869_83869_3_SMARCA2-BEND2_SMARCA2_chr9_2039900_ENST00000382194_BEND2_chrX_18213562_ENST00000380033_length(transcript)=4239nt_BP=794nt
GTAGATGTCCACGCCCACAGACCCTGGTGCGATGCCCCACCCAGGGCCTTCGCCGGGGCCTGGGCCTTCCCCTGGGCCAATTCTTGGGCC
TAGTCCAGGACCAGGACCATCCCCAGGTTCCGTCCACAGCATGATGGGGCCAAGTCCTGGACCTCCAAGTGTCTCCCATCCTATGCCGAC
GATGGGGTCCACAGACTTCCCACAGGAAGGCATGCATCAAATGCATAAGCCCATCGATGGTATACATGACAAGGGGATTGTAGAAGACAT
CCATTGTGGATCCATGAAGGGCACTGGTATGCGACCACCTCACCCAGGCATGGGCCCTCCCCAGAGTCCAATGGATCAACACAGCCAAGG
TTATATGTCACCACACCCATCTCCATTAGGAGCCCCAGAGCACGTCTCCAGCCCTATGTCTGGAGGAGGCCCAACTCCACCTCAGATGCC
ACCAAGCCAGCCGGGGGCCCTCATCCCAGGTGATCCGCAGGCCATGAGCCAGCCCAACAGAGGTCCCTCACCTTTCAGTCCTGTCCAGCT
GCATCAGCTTCGAGCTCAGATTTTAGCTTATAAAATGCTGGCCCGAGGCCAGCCCCTCCCCGAAACGCTGCAGCTTGCAGTCCAGGGGAA
AAGGACGTTGCCTGGCTTGCAGCAACAACAGCAGCAGCAACAGCAGCAGCAGCAGCAGCAGCAGCAGCAGCAGCAGCAGCAACAGCAGCC
GCAGCAGCAGCCGCCGCAACCACAGACGCAGCAACAACAGCAGCCGGCCCTTGTTAACTACAACAGACCATCTGCTGAGAAAATTATACT
TACTGAAATGCCAGGAACAACAGAAACCAACGTGGAAAATAACTCTCAGACAGTGTATTACCCAGCTTTATCGGGAAATACGAGTGCCCC
ATATCCAGCCTCTTCATATCTTCCCATCACTTCTAATTTTGAATCTGGCCCACAAATGAGTTATGGGACAATGAGTTACTCAACTGAAAT
GAAAAATAACTGTGACCAAGATGATGCTTCAGCATCTGCCTGCCTCACTCCCGATTTTGCACTGTTACCTCTGAATATTTTGGTAAAAGT
AGACACCAACACGGAAAACAGCGTCAACACAATGAATCGCTCAACTTTATTGGACAGTGACAGTGGCCAGGATTCTTCCTCATCATCTGT
CTGTATCCCTCCCAAGTATGGCTATCTTGGTGATCCAAAAAGAAATGTCAGAGTACTTAAAATCCATTTGCTGGCCGTACAAAATATGGC
CAAACCTAAGCAAGCAGCCTGCTACTTGGTTCGTATTTTGTTCTCCAAGGAAATCCTGATTAGCAGCTCAGTGGATATCCATTTGAAAGA
CAGCCAATCCCTCGACCCGAACAAAATGGCTGCATTGAGAGAATATCTGGCAACAACTTTTCCCACCTGTGATTTGCATGAACATGGAAA
AGACTGGCAGGACTGTATTTCTGGTATCAATTCTATGATCTACTGTTTATGTTCTGAAGGCAAGAGTACTCCAAAAACTGTTCGCAAAAA
TAAAAAACGTACCAACCGTGTTGCATCGGCATCTGCAGATAGAAATGACCAAAGGGGCAGAGATGGTGGTGAAGGCTGTTCTTGGATGTT
TCAGCCAATGAATAACTCCAAAATGAGAGAAAAGAGGAACTTGCAGCCAAACAGTAATGCTATCCCTGAAGGAATGCGAGAACCTTCCAC
TGATAATCCAGAGGAACCTGGTGAAGCATGGAGCTATTTTGGAAGACCATGGAGAAATATACGGATGCCATGTTCAGTACTGACTTTGGC
AAAAACTAAGTCTTGCGCAAGCCTGTCGGCTAGATACCTTATTCAGAAACTCTTCACAAAAGATGTCCTGGTCCAAAGTAACGTCTATGG
CAATCTGAAGCATGGCCTGTGTGCCCTTGACCCCAATAAGATTAGTGCTCTCCGAGAGTTCCTCCAAGAAAACTACCCAATTTGTGATCT
CTCGGAAAATGGAAGAGACTGGAAGTCGTGTGTGACCTCCATCAACAGCGGTATCCGTAGCCTTAGACATGACGTCAGAAGGGCTGAAGC
CAGGTCTCAGTCGCTTCCAGCAGTGACCCCTCCAGAGCTGGAGCAGGAGTCAAAGCCAGGAGATCCCGACGCCACTGACCCAAGCACCTG
AACGGCAGCTGCCAAACTTTTTTTTTTTTTTTAACTGTTAAGACTATTTTGTAAGTTTCTCAAGTTCTAATTCCAAAATCAGCCTGCTGT
ACTGGCAGAGTAGTTTGCATTGACACCTGTAGTAATCGCCAAACCTCTTTTTCTGCTCATAAAGGAGGTAGAATCACATTAGGAAGATAC
GTAATGTTTCATCTGTGGATTTGATGACAACCTCTGATTGAGGGAATGGTAGTAAACTCCTCATGGGCTTGTGACCCATGGCTTTGACTT
AGATAATTGACATTAATATACTTTGTTTTTTTGATAAGGTAGAGAAAGAAATTCAATAGAAAGTAAGGAGCCACTCAGTCAAATAATATA
ATTCGTATAAAACTTGACAAGTCTTTTTATTTTTGTGACTTGTGAGATAGTTTAAGATATTTTTATGTGACCAATTTGTAGAATGAATAC
ATATTTTCAAAGTTATCTTTTCAAAATTCAACTTTTAGAGTATTTTAGCAAAATATATGTATAGTTTATAATATAGAAGTATAGCTTTAT
AAAGATATTAAGGATTTATTTTTTAAAATAATTCTCTGAATAGTTTGCTGTAGTAGTTGCCTTCAGCTTAATAAAACCATAGTACTTCTA
CATACATCTTTATAAGTTAGGCTATGCCTACAAAGGTCTTAAAAAGTAGATAATTTACCGGGTGTAGTGGCTCACACCTGTAATCCCAGC
ACTTTGGGAGGCCGAGACGGGTGGATCACCTGAGGTCAGGGGTTCGAGACCAGCCTGGCCAACATGACGAAACCCCATCTCTACTAAAAA
TACAAAAAAAGTAGCCAGGCATGGTGGCAAGCACCTGTAGTCCCAGTTACTCGGGTGGCTGAGGCAGGAGAATCACTTGAACCTGGGAGG
TGGAGACTGCAGTGAGCCGAGATTGTGCCACTGCACTCGAGCCTGGGTGACAGAGTGAGACTCCGTCTCGGGAAAAGAAAAAAAAGAAGT
AGATAATTAAAAAAATCTTGCATAAAAAAAAATCTTCCATAAAGGGCAAAAAGGCTTTAACTTCCATTATTCAGATTTAATCCAACTAAG
ATAGTCTTTGGCTTCATTCACTGTTCAGTTTCACAAGTTTTTTACAACTACTAGTAACAGAGCTAATACAGAATAGTAATCCACATTATA
AACATAGATCAAAATACCACATCATACCCCATAAATACATGCAGTTATTATTTGTCAATTAAAAATAAAATTTTTTTAAAAGAAAAGTAC
AGTTCGACCCTAGGCAAGAAGAAATTTCAAATTGTATATGCATATTTTGAATTTGGTTTATATTTTGTGGTATCTGAAATATTCCCTGGA
CTAGAAGCAAAACCACAGAAACAAAACTTTACATTTAGAAAAAAATTTCAAGACTTCTATTGCTAACTTTATTACATTAGTGGTTTTTAG
AAGTTATTTAGAGCAGTCTTGTCTGATAGAACTTTCCACCATGATGGAAATGTAAATAAATATACCACATTAAAAATATAAATTTGCAAT
GTCCAATAGGCTCGTATGGCTATTGAGCATTTAAGATGTAATTAATTAGACAGAGGAAGTAAATTTAACATTTTCTCTCATTTTAGCTAA
TTAGAATTTAAAGTGAAATAGCCACAAGTGGATAGTGGCTACTGTGTTGGATGGCACAGTTCAAAATGCCTCTTATTTATAAAAAAAAGT
GTTTAAAAGTGGTTCCCATGGCTTGAAGAGGAATAATATACACATAACTTCTTTAAAATCACATTTTGTTTGAGATGGAGATCTTGCTAT
ATTGCCCAGGCTTATCTGGAACTCCTGGGCTCAAGAGGGAGGATCACATTTGACTGGACAAAATACATTTTATAAAGGTGTTTTGTATTT
TATGTTAAAGTGGAATTGTGTCTTCAAAATTGTGTCTTCAAAATTTCACAAGTTAATACTATTACTGTATTAGTCCAATGTTAAACATTT
TAAATGCCTGCTCATAAGACTCATTTTTGATAAATAAATGTATCTTTAATGTTTTGTTTCCCAAATAGATACAATAAATAAACATTTAAA

>83869_83869_3_SMARCA2-BEND2_SMARCA2_chr9_2039900_ENST00000382194_BEND2_chrX_18213562_ENST00000380033_length(amino acids)=718AA_BP=261
MSTPTDPGAMPHPGPSPGPGPSPGPILGPSPGPGPSPGSVHSMMGPSPGPPSVSHPMPTMGSTDFPQEGMHQMHKPIDGIHDKGIVEDIH
CGSMKGTGMRPPHPGMGPPQSPMDQHSQGYMSPHPSPLGAPEHVSSPMSGGGPTPPQMPPSQPGALIPGDPQAMSQPNRGPSPFSPVQLH
QLRAQILAYKMLARGQPLPETLQLAVQGKRTLPGLQQQQQQQQQQQQQQQQQQQQQQQPQQQPPQPQTQQQQQPALVNYNRPSAEKIILT
EMPGTTETNVENNSQTVYYPALSGNTSAPYPASSYLPITSNFESGPQMSYGTMSYSTEMKNNCDQDDASASACLTPDFALLPLNILVKVD
TNTENSVNTMNRSTLLDSDSGQDSSSSSVCIPPKYGYLGDPKRNVRVLKIHLLAVQNMAKPKQAACYLVRILFSKEILISSSVDIHLKDS
QSLDPNKMAALREYLATTFPTCDLHEHGKDWQDCISGINSMIYCLCSEGKSTPKTVRKNKKRTNRVASASADRNDQRGRDGGEGCSWMFQ
PMNNSKMREKRNLQPNSNAIPEGMREPSTDNPEEPGEAWSYFGRPWRNIRMPCSVLTLAKTKSCASLSARYLIQKLFTKDVLVQSNVYGN

--------------------------------------------------------------
>83869_83869_4_SMARCA2-BEND2_SMARCA2_chr9_2039900_ENST00000382203_BEND2_chrX_18213562_ENST00000380033_length(transcript)=4444nt_BP=999nt
TCAGAAGAAAGCCCCGAGATCACAGAGACCCGGCGAGATCACAGAGACCCGGCCTGAAGGAACGTGGAAAGACCAATGTACCTGTTTTGA
CCGGTTGCCTGGAGCAAGAAGTTCCAGTTGGGGAGAATTTTCAGAAGATAAAGTCGGAGATTGTGGAAAGACTTGACTTGCAGCATTACT
CTACTGACTGGCAGAGACAGGAGAGGTAGATGTCCACGCCCACAGACCCTGGTGCGATGCCCCACCCAGGGCCTTCGCCGGGGCCTGGGC
CTTCCCCTGGGCCAATTCTTGGGCCTAGTCCAGGACCAGGACCATCCCCAGGTTCCGTCCACAGCATGATGGGGCCAAGTCCTGGACCTC
CAAGTGTCTCCCATCCTATGCCGACGATGGGGTCCACAGACTTCCCACAGGAAGGCATGCATCAAATGCATAAGCCCATCGATGGTATAC
ATGACAAGGGGATTGTAGAAGACATCCATTGTGGATCCATGAAGGGCACTGGTATGCGACCACCTCACCCAGGCATGGGCCCTCCCCAGA
GTCCAATGGATCAACACAGCCAAGGTTATATGTCACCACACCCATCTCCATTAGGAGCCCCAGAGCACGTCTCCAGCCCTATGTCTGGAG
GAGGCCCAACTCCACCTCAGATGCCACCAAGCCAGCCGGGGGCCCTCATCCCAGGTGATCCGCAGGCCATGAGCCAGCCCAACAGAGGTC
CCTCACCTTTCAGTCCTGTCCAGCTGCATCAGCTTCGAGCTCAGATTTTAGCTTATAAAATGCTGGCCCGAGGCCAGCCCCTCCCCGAAA
CGCTGCAGCTTGCAGTCCAGGGGAAAAGGACGTTGCCTGGCTTGCAGCAACAACAGCAGCAGCAACAGCAGCAGCAGCAGCAGCAGCAGC
AGCAGCAGCAGCAGCAACAGCAGCCGCAGCAGCAGCCGCCGCAACCACAGACGCAGCAACAACAGCAGCCGGCCCTTGTTAACTACAACA
GACCATCTGCTGAGAAAATTATACTTACTGAAATGCCAGGAACAACAGAAACCAACGTGGAAAATAACTCTCAGACAGTGTATTACCCAG
CTTTATCGGGAAATACGAGTGCCCCATATCCAGCCTCTTCATATCTTCCCATCACTTCTAATTTTGAATCTGGCCCACAAATGAGTTATG
GGACAATGAGTTACTCAACTGAAATGAAAAATAACTGTGACCAAGATGATGCTTCAGCATCTGCCTGCCTCACTCCCGATTTTGCACTGT
TACCTCTGAATATTTTGGTAAAAGTAGACACCAACACGGAAAACAGCGTCAACACAATGAATCGCTCAACTTTATTGGACAGTGACAGTG
GCCAGGATTCTTCCTCATCATCTGTCTGTATCCCTCCCAAGTATGGCTATCTTGGTGATCCAAAAAGAAATGTCAGAGTACTTAAAATCC
ATTTGCTGGCCGTACAAAATATGGCCAAACCTAAGCAAGCAGCCTGCTACTTGGTTCGTATTTTGTTCTCCAAGGAAATCCTGATTAGCA
GCTCAGTGGATATCCATTTGAAAGACAGCCAATCCCTCGACCCGAACAAAATGGCTGCATTGAGAGAATATCTGGCAACAACTTTTCCCA
CCTGTGATTTGCATGAACATGGAAAAGACTGGCAGGACTGTATTTCTGGTATCAATTCTATGATCTACTGTTTATGTTCTGAAGGCAAGA
GTACTCCAAAAACTGTTCGCAAAAATAAAAAACGTACCAACCGTGTTGCATCGGCATCTGCAGATAGAAATGACCAAAGGGGCAGAGATG
GTGGTGAAGGCTGTTCTTGGATGTTTCAGCCAATGAATAACTCCAAAATGAGAGAAAAGAGGAACTTGCAGCCAAACAGTAATGCTATCC
CTGAAGGAATGCGAGAACCTTCCACTGATAATCCAGAGGAACCTGGTGAAGCATGGAGCTATTTTGGAAGACCATGGAGAAATATACGGA
TGCCATGTTCAGTACTGACTTTGGCAAAAACTAAGTCTTGCGCAAGCCTGTCGGCTAGATACCTTATTCAGAAACTCTTCACAAAAGATG
TCCTGGTCCAAAGTAACGTCTATGGCAATCTGAAGCATGGCCTGTGTGCCCTTGACCCCAATAAGATTAGTGCTCTCCGAGAGTTCCTCC
AAGAAAACTACCCAATTTGTGATCTCTCGGAAAATGGAAGAGACTGGAAGTCGTGTGTGACCTCCATCAACAGCGGTATCCGTAGCCTTA
GACATGACGTCAGAAGGGCTGAAGCCAGGTCTCAGTCGCTTCCAGCAGTGACCCCTCCAGAGCTGGAGCAGGAGTCAAAGCCAGGAGATC
CCGACGCCACTGACCCAAGCACCTGAACGGCAGCTGCCAAACTTTTTTTTTTTTTTTAACTGTTAAGACTATTTTGTAAGTTTCTCAAGT
TCTAATTCCAAAATCAGCCTGCTGTACTGGCAGAGTAGTTTGCATTGACACCTGTAGTAATCGCCAAACCTCTTTTTCTGCTCATAAAGG
AGGTAGAATCACATTAGGAAGATACGTAATGTTTCATCTGTGGATTTGATGACAACCTCTGATTGAGGGAATGGTAGTAAACTCCTCATG
GGCTTGTGACCCATGGCTTTGACTTAGATAATTGACATTAATATACTTTGTTTTTTTGATAAGGTAGAGAAAGAAATTCAATAGAAAGTA
AGGAGCCACTCAGTCAAATAATATAATTCGTATAAAACTTGACAAGTCTTTTTATTTTTGTGACTTGTGAGATAGTTTAAGATATTTTTA
TGTGACCAATTTGTAGAATGAATACATATTTTCAAAGTTATCTTTTCAAAATTCAACTTTTAGAGTATTTTAGCAAAATATATGTATAGT
TTATAATATAGAAGTATAGCTTTATAAAGATATTAAGGATTTATTTTTTAAAATAATTCTCTGAATAGTTTGCTGTAGTAGTTGCCTTCA
GCTTAATAAAACCATAGTACTTCTACATACATCTTTATAAGTTAGGCTATGCCTACAAAGGTCTTAAAAAGTAGATAATTTACCGGGTGT
AGTGGCTCACACCTGTAATCCCAGCACTTTGGGAGGCCGAGACGGGTGGATCACCTGAGGTCAGGGGTTCGAGACCAGCCTGGCCAACAT
GACGAAACCCCATCTCTACTAAAAATACAAAAAAAGTAGCCAGGCATGGTGGCAAGCACCTGTAGTCCCAGTTACTCGGGTGGCTGAGGC
AGGAGAATCACTTGAACCTGGGAGGTGGAGACTGCAGTGAGCCGAGATTGTGCCACTGCACTCGAGCCTGGGTGACAGAGTGAGACTCCG
TCTCGGGAAAAGAAAAAAAAGAAGTAGATAATTAAAAAAATCTTGCATAAAAAAAAATCTTCCATAAAGGGCAAAAAGGCTTTAACTTCC
ATTATTCAGATTTAATCCAACTAAGATAGTCTTTGGCTTCATTCACTGTTCAGTTTCACAAGTTTTTTACAACTACTAGTAACAGAGCTA
ATACAGAATAGTAATCCACATTATAAACATAGATCAAAATACCACATCATACCCCATAAATACATGCAGTTATTATTTGTCAATTAAAAA
TAAAATTTTTTTAAAAGAAAAGTACAGTTCGACCCTAGGCAAGAAGAAATTTCAAATTGTATATGCATATTTTGAATTTGGTTTATATTT
TGTGGTATCTGAAATATTCCCTGGACTAGAAGCAAAACCACAGAAACAAAACTTTACATTTAGAAAAAAATTTCAAGACTTCTATTGCTA
ACTTTATTACATTAGTGGTTTTTAGAAGTTATTTAGAGCAGTCTTGTCTGATAGAACTTTCCACCATGATGGAAATGTAAATAAATATAC
CACATTAAAAATATAAATTTGCAATGTCCAATAGGCTCGTATGGCTATTGAGCATTTAAGATGTAATTAATTAGACAGAGGAAGTAAATT
TAACATTTTCTCTCATTTTAGCTAATTAGAATTTAAAGTGAAATAGCCACAAGTGGATAGTGGCTACTGTGTTGGATGGCACAGTTCAAA
ATGCCTCTTATTTATAAAAAAAAGTGTTTAAAAGTGGTTCCCATGGCTTGAAGAGGAATAATATACACATAACTTCTTTAAAATCACATT
TTGTTTGAGATGGAGATCTTGCTATATTGCCCAGGCTTATCTGGAACTCCTGGGCTCAAGAGGGAGGATCACATTTGACTGGACAAAATA
CATTTTATAAAGGTGTTTTGTATTTTATGTTAAAGTGGAATTGTGTCTTCAAAATTGTGTCTTCAAAATTTCACAAGTTAATACTATTAC
TGTATTAGTCCAATGTTAAACATTTTAAATGCCTGCTCATAAGACTCATTTTTGATAAATAAATGTATCTTTAATGTTTTGTTTCCCAAA

>83869_83869_4_SMARCA2-BEND2_SMARCA2_chr9_2039900_ENST00000382203_BEND2_chrX_18213562_ENST00000380033_length(amino acids)=718AA_BP=261
MSTPTDPGAMPHPGPSPGPGPSPGPILGPSPGPGPSPGSVHSMMGPSPGPPSVSHPMPTMGSTDFPQEGMHQMHKPIDGIHDKGIVEDIH
CGSMKGTGMRPPHPGMGPPQSPMDQHSQGYMSPHPSPLGAPEHVSSPMSGGGPTPPQMPPSQPGALIPGDPQAMSQPNRGPSPFSPVQLH
QLRAQILAYKMLARGQPLPETLQLAVQGKRTLPGLQQQQQQQQQQQQQQQQQQQQQQQPQQQPPQPQTQQQQQPALVNYNRPSAEKIILT
EMPGTTETNVENNSQTVYYPALSGNTSAPYPASSYLPITSNFESGPQMSYGTMSYSTEMKNNCDQDDASASACLTPDFALLPLNILVKVD
TNTENSVNTMNRSTLLDSDSGQDSSSSSVCIPPKYGYLGDPKRNVRVLKIHLLAVQNMAKPKQAACYLVRILFSKEILISSSVDIHLKDS
QSLDPNKMAALREYLATTFPTCDLHEHGKDWQDCISGINSMIYCLCSEGKSTPKTVRKNKKRTNRVASASADRNDQRGRDGGEGCSWMFQ
PMNNSKMREKRNLQPNSNAIPEGMREPSTDNPEEPGEAWSYFGRPWRNIRMPCSVLTLAKTKSCASLSARYLIQKLFTKDVLVQSNVYGN

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Fusion Gene PPI Analysis for SMARCA2-BEND2


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for SMARCA2-BEND2


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for SMARCA2-BEND2


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource