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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:SMARCB1-RPLP0 (FusionGDB2 ID:83928)

Fusion Gene Summary for SMARCB1-RPLP0

check button Fusion gene summary
Fusion gene informationFusion gene name: SMARCB1-RPLP0
Fusion gene ID: 83928
HgeneTgene
Gene symbol

SMARCB1

RPLP0

Gene ID

6598

6175

Gene nameSWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1ribosomal protein lateral stalk subunit P0
SynonymsBAF47|CSS3|INI1|MRD15|PPP1R144|RDT|RTPS1|SNF5|SNF5L1|SWNTS1|Sfh1p|Snr1|hSNFSL10E|LP0|P0|PRLP0|RPP0
Cytomap

22q11.23|22q11

12q24.23

Type of geneprotein-codingprotein-coding
DescriptionSWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1BRG1-associated factor 47SNF5 homologSWI/SNF-related matrix-associated proteinhSNF5integrase interactor 1 proteinmalignant rhabdoid tumor suppressorprotein60S acidic ribosomal protein P060S ribosomal protein L10Eacidic ribosomal phosphoprotein P0large ribosomal subunit protein uL10neutral ribosomal phosphoprotein P0ribosomal protein, large, P0
Modification date2020031320200313
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000263121, ENST00000344921, 
ENST00000407082, ENST00000407422, 
ENST00000477836, 		ENST00000550296, 
ENST00000228306, ENST00000313104, 
ENST00000392514, ENST00000546989, 
ENST00000551150, ENST00000552292, 
Fusion gene scores* DoF score14 X 15 X 8=168024 X 10 X 14=3360
# samples 1928
** MAII scorelog2(19/1680*10)=-3.14438990933518
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(28/3360*10)=-3.58496250072116
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: SMARCB1 [Title/Abstract] AND RPLP0 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointSMARCB1(24129449)-RPLP0(120635265), # samples:1
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneSMARCB1

GO:0006337

nucleosome disassembly

8895581

HgeneSMARCB1

GO:0006338

chromatin remodeling

11726552

HgeneSMARCB1

GO:0039692

single stranded viral RNA replication via double stranded DNA intermediate

14963118

HgeneSMARCB1

GO:0045944

positive regulation of transcription by RNA polymerase II

11950834

HgeneSMARCB1

GO:0051091

positive regulation of DNA-binding transcription factor activity

11950834

HgeneSMARCB1

GO:1902661

positive regulation of glucose mediated signaling pathway

22368283


check buttonFusion gene breakpoints across SMARCB1 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across RPLP0 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4OVTCGA-04-1651SMARCB1chr22

24129449

+RPLP0chr12

120635265

-


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Fusion Gene ORF analysis for SMARCB1-RPLP0

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000263121ENST00000550296SMARCB1chr22

24129449

+RPLP0chr12

120635265

-
5CDS-intronENST00000344921ENST00000550296SMARCB1chr22

24129449

+RPLP0chr12

120635265

-
5CDS-intronENST00000407082ENST00000550296SMARCB1chr22

24129449

+RPLP0chr12

120635265

-
5CDS-intronENST00000407422ENST00000550296SMARCB1chr22

24129449

+RPLP0chr12

120635265

-
In-frameENST00000263121ENST00000228306SMARCB1chr22

24129449

+RPLP0chr12

120635265

-
In-frameENST00000263121ENST00000313104SMARCB1chr22

24129449

+RPLP0chr12

120635265

-
In-frameENST00000263121ENST00000392514SMARCB1chr22

24129449

+RPLP0chr12

120635265

-
In-frameENST00000263121ENST00000546989SMARCB1chr22

24129449

+RPLP0chr12

120635265

-
In-frameENST00000263121ENST00000551150SMARCB1chr22

24129449

+RPLP0chr12

120635265

-
In-frameENST00000263121ENST00000552292SMARCB1chr22

24129449

+RPLP0chr12

120635265

-
In-frameENST00000344921ENST00000228306SMARCB1chr22

24129449

+RPLP0chr12

120635265

-
In-frameENST00000344921ENST00000313104SMARCB1chr22

24129449

+RPLP0chr12

120635265

-
In-frameENST00000344921ENST00000392514SMARCB1chr22

24129449

+RPLP0chr12

120635265

-
In-frameENST00000344921ENST00000546989SMARCB1chr22

24129449

+RPLP0chr12

120635265

-
In-frameENST00000344921ENST00000551150SMARCB1chr22

24129449

+RPLP0chr12

120635265

-
In-frameENST00000344921ENST00000552292SMARCB1chr22

24129449

+RPLP0chr12

120635265

-
In-frameENST00000407082ENST00000228306SMARCB1chr22

24129449

+RPLP0chr12

120635265

-
In-frameENST00000407082ENST00000313104SMARCB1chr22

24129449

+RPLP0chr12

120635265

-
In-frameENST00000407082ENST00000392514SMARCB1chr22

24129449

+RPLP0chr12

120635265

-
In-frameENST00000407082ENST00000546989SMARCB1chr22

24129449

+RPLP0chr12

120635265

-
In-frameENST00000407082ENST00000551150SMARCB1chr22

24129449

+RPLP0chr12

120635265

-
In-frameENST00000407082ENST00000552292SMARCB1chr22

24129449

+RPLP0chr12

120635265

-
In-frameENST00000407422ENST00000228306SMARCB1chr22

24129449

+RPLP0chr12

120635265

-
In-frameENST00000407422ENST00000313104SMARCB1chr22

24129449

+RPLP0chr12

120635265

-
In-frameENST00000407422ENST00000392514SMARCB1chr22

24129449

+RPLP0chr12

120635265

-
In-frameENST00000407422ENST00000546989SMARCB1chr22

24129449

+RPLP0chr12

120635265

-
In-frameENST00000407422ENST00000551150SMARCB1chr22

24129449

+RPLP0chr12

120635265

-
In-frameENST00000407422ENST00000552292SMARCB1chr22

24129449

+RPLP0chr12

120635265

-
intron-3CDSENST00000477836ENST00000228306SMARCB1chr22

24129449

+RPLP0chr12

120635265

-
intron-3CDSENST00000477836ENST00000313104SMARCB1chr22

24129449

+RPLP0chr12

120635265

-
intron-3CDSENST00000477836ENST00000392514SMARCB1chr22

24129449

+RPLP0chr12

120635265

-
intron-3CDSENST00000477836ENST00000546989SMARCB1chr22

24129449

+RPLP0chr12

120635265

-
intron-3CDSENST00000477836ENST00000551150SMARCB1chr22

24129449

+RPLP0chr12

120635265

-
intron-3CDSENST00000477836ENST00000552292SMARCB1chr22

24129449

+RPLP0chr12

120635265

-
intron-intronENST00000477836ENST00000550296SMARCB1chr22

24129449

+RPLP0chr12

120635265

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000344921SMARCB1chr2224129449+ENST00000392514RPLP0chr12120635265-690300207602131
ENST00000344921SMARCB1chr2224129449+ENST00000551150RPLP0chr12120635265-677300207602131
ENST00000344921SMARCB1chr2224129449+ENST00000552292RPLP0chr12120635265-67430020746184
ENST00000344921SMARCB1chr2224129449+ENST00000313104RPLP0chr12120635265-674300207602131
ENST00000344921SMARCB1chr2224129449+ENST00000546989RPLP0chr12120635265-674300207602131
ENST00000344921SMARCB1chr2224129449+ENST00000228306RPLP0chr12120635265-669300207602131
ENST00000263121SMARCB1chr2224129449+ENST00000392514RPLP0chr12120635265-679289196591131
ENST00000263121SMARCB1chr2224129449+ENST00000551150RPLP0chr12120635265-666289196591131
ENST00000263121SMARCB1chr2224129449+ENST00000552292RPLP0chr12120635265-66328919645084
ENST00000263121SMARCB1chr2224129449+ENST00000313104RPLP0chr12120635265-663289196591131
ENST00000263121SMARCB1chr2224129449+ENST00000546989RPLP0chr12120635265-663289196591131
ENST00000263121SMARCB1chr2224129449+ENST00000228306RPLP0chr12120635265-658289196591131
ENST00000407422SMARCB1chr2224129449+ENST00000392514RPLP0chr12120635265-659269176571131
ENST00000407422SMARCB1chr2224129449+ENST00000551150RPLP0chr12120635265-646269176571131
ENST00000407422SMARCB1chr2224129449+ENST00000552292RPLP0chr12120635265-64326917643084
ENST00000407422SMARCB1chr2224129449+ENST00000313104RPLP0chr12120635265-643269176571131
ENST00000407422SMARCB1chr2224129449+ENST00000546989RPLP0chr12120635265-643269176571131
ENST00000407422SMARCB1chr2224129449+ENST00000228306RPLP0chr12120635265-638269176571131
ENST00000407082SMARCB1chr2224129449+ENST00000392514RPLP0chr12120635265-642252159554131
ENST00000407082SMARCB1chr2224129449+ENST00000551150RPLP0chr12120635265-629252159554131
ENST00000407082SMARCB1chr2224129449+ENST00000552292RPLP0chr12120635265-62625215941384
ENST00000407082SMARCB1chr2224129449+ENST00000313104RPLP0chr12120635265-626252159554131
ENST00000407082SMARCB1chr2224129449+ENST00000546989RPLP0chr12120635265-626252159554131
ENST00000407082SMARCB1chr2224129449+ENST00000228306RPLP0chr12120635265-621252159554131

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000344921ENST00000392514SMARCB1chr2224129449+RPLP0chr12120635265-0.0042629340.9957371
ENST00000344921ENST00000551150SMARCB1chr2224129449+RPLP0chr12120635265-0.0045463250.9954536
ENST00000344921ENST00000552292SMARCB1chr2224129449+RPLP0chr12120635265-0.0186415760.98135847
ENST00000344921ENST00000313104SMARCB1chr2224129449+RPLP0chr12120635265-0.0045385610.9954614
ENST00000344921ENST00000546989SMARCB1chr2224129449+RPLP0chr12120635265-0.0045385610.9954614
ENST00000344921ENST00000228306SMARCB1chr2224129449+RPLP0chr12120635265-0.0042265640.9957735
ENST00000263121ENST00000392514SMARCB1chr2224129449+RPLP0chr12120635265-0.0041167660.9958832
ENST00000263121ENST00000551150SMARCB1chr2224129449+RPLP0chr12120635265-0.0040820030.995918
ENST00000263121ENST00000552292SMARCB1chr2224129449+RPLP0chr12120635265-0.0215234330.9784766
ENST00000263121ENST00000313104SMARCB1chr2224129449+RPLP0chr12120635265-0.00388330.99611676
ENST00000263121ENST00000546989SMARCB1chr2224129449+RPLP0chr12120635265-0.00388330.99611676
ENST00000263121ENST00000228306SMARCB1chr2224129449+RPLP0chr12120635265-0.0035658810.9964341
ENST00000407422ENST00000392514SMARCB1chr2224129449+RPLP0chr12120635265-0.003317510.99668247
ENST00000407422ENST00000551150SMARCB1chr2224129449+RPLP0chr12120635265-0.0031985030.9968015
ENST00000407422ENST00000552292SMARCB1chr2224129449+RPLP0chr12120635265-0.015240240.98475975
ENST00000407422ENST00000313104SMARCB1chr2224129449+RPLP0chr12120635265-0.0031670520.9968329
ENST00000407422ENST00000546989SMARCB1chr2224129449+RPLP0chr12120635265-0.0031670520.9968329
ENST00000407422ENST00000228306SMARCB1chr2224129449+RPLP0chr12120635265-0.0027780030.99722207
ENST00000407082ENST00000392514SMARCB1chr2224129449+RPLP0chr12120635265-0.0046809250.99531907
ENST00000407082ENST00000551150SMARCB1chr2224129449+RPLP0chr12120635265-0.0046238620.9953761
ENST00000407082ENST00000552292SMARCB1chr2224129449+RPLP0chr12120635265-0.0220096130.9779904
ENST00000407082ENST00000313104SMARCB1chr2224129449+RPLP0chr12120635265-0.00449540.9955047
ENST00000407082ENST00000546989SMARCB1chr2224129449+RPLP0chr12120635265-0.00449540.9955047
ENST00000407082ENST00000228306SMARCB1chr2224129449+RPLP0chr12120635265-0.0039814470.9960186

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Fusion Genomic Features for SMARCB1-RPLP0


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for SMARCB1-RPLP0


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr22:24129449/chr12:120635265)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneSMARCB1chr22:24129449chr12:120635265ENST00000263121+19183_24331386.0RegionNote=HIV-1 integrase-binding
HgeneSMARCB1chr22:24129449chr12:120635265ENST00000263121+19186_24531386.0RegionMYC-binding
HgeneSMARCB1chr22:24129449chr12:120635265ENST00000263121+19186_31931386.0RegionNote=2 X approximate tandem repeats
HgeneSMARCB1chr22:24129449chr12:120635265ENST00000263121+191_11331386.0RegionDNA-binding
HgeneSMARCB1chr22:24129449chr12:120635265ENST00000407422+19183_24331377.0RegionNote=HIV-1 integrase-binding
HgeneSMARCB1chr22:24129449chr12:120635265ENST00000407422+19186_24531377.0RegionMYC-binding
HgeneSMARCB1chr22:24129449chr12:120635265ENST00000407422+19186_31931377.0RegionNote=2 X approximate tandem repeats
HgeneSMARCB1chr22:24129449chr12:120635265ENST00000407422+191_11331377.0RegionDNA-binding
HgeneSMARCB1chr22:24129449chr12:120635265ENST00000263121+19259_31931386.0RepeatNote=2
HgeneSMARCB1chr22:24129449chr12:120635265ENST00000407422+19259_31931377.0RepeatNote=2


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Fusion Gene Sequence for SMARCB1-RPLP0


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>83928_83928_1_SMARCB1-RPLP0_SMARCB1_chr22_24129449_ENST00000263121_RPLP0_chr12_120635265_ENST00000228306_length(transcript)=658nt_BP=289nt
CTGCGCACTGAGGGCGGCCTGGTCGTCGTCTGCGGCGGCGGCGGCGGCTGAGGAGCCCGGCTGAGGCGCCAGTACCCGGCCCGGTCCGCA
TTTCGCCTTCCGGCTTCGGTTTCCCTCGGCCCAGCACGCCCCGGCCCCGCCCCAGCCCTCCTGATCCCTCGCAGCCCGGCTCCGGCCGCC
CGCCTCTGCCGCCGCAATGATGATGATGGCGCTGAGCAAGACCTTCGGGCAGAAGCCCGTGAAGTTCCAGCTGGAGGACGACGGCGAGTT
CTACATGATCGGCTCCGAGGGTGTCCGCAATGTTGCCAGTGTCTGTCTGCAGATTGGCTACCCAACTGTTGCATCAGTACCCCATTCTAT
CATCAACGGGTACAAACGAGTCCTGGCCTTGTCTGTGGAGACGGATTACACCTTCCCACTTGCTGAAAAGGTCAAGGCCTTCTTGGCTGA
TCCATCTGCCTTTGTGGCTGCTGCCCCTGTGGCTGCTGCCACCACAGCTGCTCCTGCTGCTGCTGCAGCCCCAGCTAAGGTTGAAGCCAA
GGAAGAGTCGGAGGAGTCGGACGAGGATATGGGATTTGGTCTCTTTGACTAATCACCAAAAAGCAACCAACTTAGCCAGTTTTATTTGCA

>83928_83928_1_SMARCB1-RPLP0_SMARCB1_chr22_24129449_ENST00000263121_RPLP0_chr12_120635265_ENST00000228306_length(amino acids)=131AA_BP=31
MMMMALSKTFGQKPVKFQLEDDGEFYMIGSEGVRNVASVCLQIGYPTVASVPHSIINGYKRVLALSVETDYTFPLAEKVKAFLADPSAFV

--------------------------------------------------------------
>83928_83928_2_SMARCB1-RPLP0_SMARCB1_chr22_24129449_ENST00000263121_RPLP0_chr12_120635265_ENST00000313104_length(transcript)=663nt_BP=289nt
CTGCGCACTGAGGGCGGCCTGGTCGTCGTCTGCGGCGGCGGCGGCGGCTGAGGAGCCCGGCTGAGGCGCCAGTACCCGGCCCGGTCCGCA
TTTCGCCTTCCGGCTTCGGTTTCCCTCGGCCCAGCACGCCCCGGCCCCGCCCCAGCCCTCCTGATCCCTCGCAGCCCGGCTCCGGCCGCC
CGCCTCTGCCGCCGCAATGATGATGATGGCGCTGAGCAAGACCTTCGGGCAGAAGCCCGTGAAGTTCCAGCTGGAGGACGACGGCGAGTT
CTACATGATCGGCTCCGAGGGTGTCCGCAATGTTGCCAGTGTCTGTCTGCAGATTGGCTACCCAACTGTTGCATCAGTACCCCATTCTAT
CATCAACGGGTACAAACGAGTCCTGGCCTTGTCTGTGGAGACGGATTACACCTTCCCACTTGCTGAAAAGGTCAAGGCCTTCTTGGCTGA
TCCATCTGCCTTTGTGGCTGCTGCCCCTGTGGCTGCTGCCACCACAGCTGCTCCTGCTGCTGCTGCAGCCCCAGCTAAGGTTGAAGCCAA
GGAAGAGTCGGAGGAGTCGGACGAGGATATGGGATTTGGTCTCTTTGACTAATCACCAAAAAGCAACCAACTTAGCCAGTTTTATTTGCA

>83928_83928_2_SMARCB1-RPLP0_SMARCB1_chr22_24129449_ENST00000263121_RPLP0_chr12_120635265_ENST00000313104_length(amino acids)=131AA_BP=31
MMMMALSKTFGQKPVKFQLEDDGEFYMIGSEGVRNVASVCLQIGYPTVASVPHSIINGYKRVLALSVETDYTFPLAEKVKAFLADPSAFV

--------------------------------------------------------------
>83928_83928_3_SMARCB1-RPLP0_SMARCB1_chr22_24129449_ENST00000263121_RPLP0_chr12_120635265_ENST00000392514_length(transcript)=679nt_BP=289nt
CTGCGCACTGAGGGCGGCCTGGTCGTCGTCTGCGGCGGCGGCGGCGGCTGAGGAGCCCGGCTGAGGCGCCAGTACCCGGCCCGGTCCGCA
TTTCGCCTTCCGGCTTCGGTTTCCCTCGGCCCAGCACGCCCCGGCCCCGCCCCAGCCCTCCTGATCCCTCGCAGCCCGGCTCCGGCCGCC
CGCCTCTGCCGCCGCAATGATGATGATGGCGCTGAGCAAGACCTTCGGGCAGAAGCCCGTGAAGTTCCAGCTGGAGGACGACGGCGAGTT
CTACATGATCGGCTCCGAGGGTGTCCGCAATGTTGCCAGTGTCTGTCTGCAGATTGGCTACCCAACTGTTGCATCAGTACCCCATTCTAT
CATCAACGGGTACAAACGAGTCCTGGCCTTGTCTGTGGAGACGGATTACACCTTCCCACTTGCTGAAAAGGTCAAGGCCTTCTTGGCTGA
TCCATCTGCCTTTGTGGCTGCTGCCCCTGTGGCTGCTGCCACCACAGCTGCTCCTGCTGCTGCTGCAGCCCCAGCTAAGGTTGAAGCCAA
GGAAGAGTCGGAGGAGTCGGACGAGGATATGGGATTTGGTCTCTTTGACTAATCACCAAAAAGCAACCAACTTAGCCAGTTTTATTTGCA

>83928_83928_3_SMARCB1-RPLP0_SMARCB1_chr22_24129449_ENST00000263121_RPLP0_chr12_120635265_ENST00000392514_length(amino acids)=131AA_BP=31
MMMMALSKTFGQKPVKFQLEDDGEFYMIGSEGVRNVASVCLQIGYPTVASVPHSIINGYKRVLALSVETDYTFPLAEKVKAFLADPSAFV

--------------------------------------------------------------
>83928_83928_4_SMARCB1-RPLP0_SMARCB1_chr22_24129449_ENST00000263121_RPLP0_chr12_120635265_ENST00000546989_length(transcript)=663nt_BP=289nt
CTGCGCACTGAGGGCGGCCTGGTCGTCGTCTGCGGCGGCGGCGGCGGCTGAGGAGCCCGGCTGAGGCGCCAGTACCCGGCCCGGTCCGCA
TTTCGCCTTCCGGCTTCGGTTTCCCTCGGCCCAGCACGCCCCGGCCCCGCCCCAGCCCTCCTGATCCCTCGCAGCCCGGCTCCGGCCGCC
CGCCTCTGCCGCCGCAATGATGATGATGGCGCTGAGCAAGACCTTCGGGCAGAAGCCCGTGAAGTTCCAGCTGGAGGACGACGGCGAGTT
CTACATGATCGGCTCCGAGGGTGTCCGCAATGTTGCCAGTGTCTGTCTGCAGATTGGCTACCCAACTGTTGCATCAGTACCCCATTCTAT
CATCAACGGGTACAAACGAGTCCTGGCCTTGTCTGTGGAGACGGATTACACCTTCCCACTTGCTGAAAAGGTCAAGGCCTTCTTGGCTGA
TCCATCTGCCTTTGTGGCTGCTGCCCCTGTGGCTGCTGCCACCACAGCTGCTCCTGCTGCTGCTGCAGCCCCAGCTAAGGTTGAAGCCAA
GGAAGAGTCGGAGGAGTCGGACGAGGATATGGGATTTGGTCTCTTTGACTAATCACCAAAAAGCAACCAACTTAGCCAGTTTTATTTGCA

>83928_83928_4_SMARCB1-RPLP0_SMARCB1_chr22_24129449_ENST00000263121_RPLP0_chr12_120635265_ENST00000546989_length(amino acids)=131AA_BP=31
MMMMALSKTFGQKPVKFQLEDDGEFYMIGSEGVRNVASVCLQIGYPTVASVPHSIINGYKRVLALSVETDYTFPLAEKVKAFLADPSAFV

--------------------------------------------------------------
>83928_83928_5_SMARCB1-RPLP0_SMARCB1_chr22_24129449_ENST00000263121_RPLP0_chr12_120635265_ENST00000551150_length(transcript)=666nt_BP=289nt
CTGCGCACTGAGGGCGGCCTGGTCGTCGTCTGCGGCGGCGGCGGCGGCTGAGGAGCCCGGCTGAGGCGCCAGTACCCGGCCCGGTCCGCA
TTTCGCCTTCCGGCTTCGGTTTCCCTCGGCCCAGCACGCCCCGGCCCCGCCCCAGCCCTCCTGATCCCTCGCAGCCCGGCTCCGGCCGCC
CGCCTCTGCCGCCGCAATGATGATGATGGCGCTGAGCAAGACCTTCGGGCAGAAGCCCGTGAAGTTCCAGCTGGAGGACGACGGCGAGTT
CTACATGATCGGCTCCGAGGGTGTCCGCAATGTTGCCAGTGTCTGTCTGCAGATTGGCTACCCAACTGTTGCATCAGTACCCCATTCTAT
CATCAACGGGTACAAACGAGTCCTGGCCTTGTCTGTGGAGACGGATTACACCTTCCCACTTGCTGAAAAGGTCAAGGCCTTCTTGGCTGA
TCCATCTGCCTTTGTGGCTGCTGCCCCTGTGGCTGCTGCCACCACAGCTGCTCCTGCTGCTGCTGCAGCCCCAGCTAAGGTTGAAGCCAA
GGAAGAGTCGGAGGAGTCGGACGAGGATATGGGATTTGGTCTCTTTGACTAATCACCAAAAAGCAACCAACTTAGCCAGTTTTATTTGCA

>83928_83928_5_SMARCB1-RPLP0_SMARCB1_chr22_24129449_ENST00000263121_RPLP0_chr12_120635265_ENST00000551150_length(amino acids)=131AA_BP=31
MMMMALSKTFGQKPVKFQLEDDGEFYMIGSEGVRNVASVCLQIGYPTVASVPHSIINGYKRVLALSVETDYTFPLAEKVKAFLADPSAFV

--------------------------------------------------------------
>83928_83928_6_SMARCB1-RPLP0_SMARCB1_chr22_24129449_ENST00000263121_RPLP0_chr12_120635265_ENST00000552292_length(transcript)=663nt_BP=289nt
CTGCGCACTGAGGGCGGCCTGGTCGTCGTCTGCGGCGGCGGCGGCGGCTGAGGAGCCCGGCTGAGGCGCCAGTACCCGGCCCGGTCCGCA
TTTCGCCTTCCGGCTTCGGTTTCCCTCGGCCCAGCACGCCCCGGCCCCGCCCCAGCCCTCCTGATCCCTCGCAGCCCGGCTCCGGCCGCC
CGCCTCTGCCGCCGCAATGATGATGATGGCGCTGAGCAAGACCTTCGGGCAGAAGCCCGTGAAGTTCCAGCTGGAGGACGACGGCGAGTT
CTACATGATCGGCTCCGAGGTCAAGGCCTTCTTGGCTGATCCATCTGCCTTTGTGGCTGCTGCCCCTGTGGCTGCTGCCACCACAGCTGC
TCCTGCTGCTGCTGCAGCCCCAGCTAAGGTTGAAGCCAAGGAAGAGTCGGAGGAGTCGGACGAGGATATGGGATTTGGTCTCTTTGACTA
ATCACCAAAAAGCAACCAACTTAGCCAGTTTTATTTGCAAAACAAGGAAATAAAGGCTTACTTCTTTAAAAAGGTGTCCGCAATGTTGCC
AGTGTCTGTCTGCAGATTGGCTACCCAACTGTTGCATCAGTACCCCATTCTATCATCAACGGGTACAAACGAGTCCTGGCCTTGTCTGTG

>83928_83928_6_SMARCB1-RPLP0_SMARCB1_chr22_24129449_ENST00000263121_RPLP0_chr12_120635265_ENST00000552292_length(amino acids)=84AA_BP=

--------------------------------------------------------------
>83928_83928_7_SMARCB1-RPLP0_SMARCB1_chr22_24129449_ENST00000344921_RPLP0_chr12_120635265_ENST00000228306_length(transcript)=669nt_BP=300nt
AACGCCAGCGCCTGCGCACTGAGGGCGGCCTGGTCGTCGTCTGCGGCGGCGGCGGCGGCTGAGGAGCCCGGCTGAGGCGCCAGTACCCGG
CCCGGTCCGCATTTCGCCTTCCGGCTTCGGTTTCCCTCGGCCCAGCACGCCCCGGCCCCGCCCCAGCCCTCCTGATCCCTCGCAGCCCGG
CTCCGGCCGCCCGCCTCTGCCGCCGCAATGATGATGATGGCGCTGAGCAAGACCTTCGGGCAGAAGCCCGTGAAGTTCCAGCTGGAGGAC
GACGGCGAGTTCTACATGATCGGCTCCGAGGGTGTCCGCAATGTTGCCAGTGTCTGTCTGCAGATTGGCTACCCAACTGTTGCATCAGTA
CCCCATTCTATCATCAACGGGTACAAACGAGTCCTGGCCTTGTCTGTGGAGACGGATTACACCTTCCCACTTGCTGAAAAGGTCAAGGCC
TTCTTGGCTGATCCATCTGCCTTTGTGGCTGCTGCCCCTGTGGCTGCTGCCACCACAGCTGCTCCTGCTGCTGCTGCAGCCCCAGCTAAG
GTTGAAGCCAAGGAAGAGTCGGAGGAGTCGGACGAGGATATGGGATTTGGTCTCTTTGACTAATCACCAAAAAGCAACCAACTTAGCCAG

>83928_83928_7_SMARCB1-RPLP0_SMARCB1_chr22_24129449_ENST00000344921_RPLP0_chr12_120635265_ENST00000228306_length(amino acids)=131AA_BP=31
MMMMALSKTFGQKPVKFQLEDDGEFYMIGSEGVRNVASVCLQIGYPTVASVPHSIINGYKRVLALSVETDYTFPLAEKVKAFLADPSAFV

--------------------------------------------------------------
>83928_83928_8_SMARCB1-RPLP0_SMARCB1_chr22_24129449_ENST00000344921_RPLP0_chr12_120635265_ENST00000313104_length(transcript)=674nt_BP=300nt
AACGCCAGCGCCTGCGCACTGAGGGCGGCCTGGTCGTCGTCTGCGGCGGCGGCGGCGGCTGAGGAGCCCGGCTGAGGCGCCAGTACCCGG
CCCGGTCCGCATTTCGCCTTCCGGCTTCGGTTTCCCTCGGCCCAGCACGCCCCGGCCCCGCCCCAGCCCTCCTGATCCCTCGCAGCCCGG
CTCCGGCCGCCCGCCTCTGCCGCCGCAATGATGATGATGGCGCTGAGCAAGACCTTCGGGCAGAAGCCCGTGAAGTTCCAGCTGGAGGAC
GACGGCGAGTTCTACATGATCGGCTCCGAGGGTGTCCGCAATGTTGCCAGTGTCTGTCTGCAGATTGGCTACCCAACTGTTGCATCAGTA
CCCCATTCTATCATCAACGGGTACAAACGAGTCCTGGCCTTGTCTGTGGAGACGGATTACACCTTCCCACTTGCTGAAAAGGTCAAGGCC
TTCTTGGCTGATCCATCTGCCTTTGTGGCTGCTGCCCCTGTGGCTGCTGCCACCACAGCTGCTCCTGCTGCTGCTGCAGCCCCAGCTAAG
GTTGAAGCCAAGGAAGAGTCGGAGGAGTCGGACGAGGATATGGGATTTGGTCTCTTTGACTAATCACCAAAAAGCAACCAACTTAGCCAG

>83928_83928_8_SMARCB1-RPLP0_SMARCB1_chr22_24129449_ENST00000344921_RPLP0_chr12_120635265_ENST00000313104_length(amino acids)=131AA_BP=31
MMMMALSKTFGQKPVKFQLEDDGEFYMIGSEGVRNVASVCLQIGYPTVASVPHSIINGYKRVLALSVETDYTFPLAEKVKAFLADPSAFV

--------------------------------------------------------------
>83928_83928_9_SMARCB1-RPLP0_SMARCB1_chr22_24129449_ENST00000344921_RPLP0_chr12_120635265_ENST00000392514_length(transcript)=690nt_BP=300nt
AACGCCAGCGCCTGCGCACTGAGGGCGGCCTGGTCGTCGTCTGCGGCGGCGGCGGCGGCTGAGGAGCCCGGCTGAGGCGCCAGTACCCGG
CCCGGTCCGCATTTCGCCTTCCGGCTTCGGTTTCCCTCGGCCCAGCACGCCCCGGCCCCGCCCCAGCCCTCCTGATCCCTCGCAGCCCGG
CTCCGGCCGCCCGCCTCTGCCGCCGCAATGATGATGATGGCGCTGAGCAAGACCTTCGGGCAGAAGCCCGTGAAGTTCCAGCTGGAGGAC
GACGGCGAGTTCTACATGATCGGCTCCGAGGGTGTCCGCAATGTTGCCAGTGTCTGTCTGCAGATTGGCTACCCAACTGTTGCATCAGTA
CCCCATTCTATCATCAACGGGTACAAACGAGTCCTGGCCTTGTCTGTGGAGACGGATTACACCTTCCCACTTGCTGAAAAGGTCAAGGCC
TTCTTGGCTGATCCATCTGCCTTTGTGGCTGCTGCCCCTGTGGCTGCTGCCACCACAGCTGCTCCTGCTGCTGCTGCAGCCCCAGCTAAG
GTTGAAGCCAAGGAAGAGTCGGAGGAGTCGGACGAGGATATGGGATTTGGTCTCTTTGACTAATCACCAAAAAGCAACCAACTTAGCCAG

>83928_83928_9_SMARCB1-RPLP0_SMARCB1_chr22_24129449_ENST00000344921_RPLP0_chr12_120635265_ENST00000392514_length(amino acids)=131AA_BP=31
MMMMALSKTFGQKPVKFQLEDDGEFYMIGSEGVRNVASVCLQIGYPTVASVPHSIINGYKRVLALSVETDYTFPLAEKVKAFLADPSAFV

--------------------------------------------------------------
>83928_83928_10_SMARCB1-RPLP0_SMARCB1_chr22_24129449_ENST00000344921_RPLP0_chr12_120635265_ENST00000546989_length(transcript)=674nt_BP=300nt
AACGCCAGCGCCTGCGCACTGAGGGCGGCCTGGTCGTCGTCTGCGGCGGCGGCGGCGGCTGAGGAGCCCGGCTGAGGCGCCAGTACCCGG
CCCGGTCCGCATTTCGCCTTCCGGCTTCGGTTTCCCTCGGCCCAGCACGCCCCGGCCCCGCCCCAGCCCTCCTGATCCCTCGCAGCCCGG
CTCCGGCCGCCCGCCTCTGCCGCCGCAATGATGATGATGGCGCTGAGCAAGACCTTCGGGCAGAAGCCCGTGAAGTTCCAGCTGGAGGAC
GACGGCGAGTTCTACATGATCGGCTCCGAGGGTGTCCGCAATGTTGCCAGTGTCTGTCTGCAGATTGGCTACCCAACTGTTGCATCAGTA
CCCCATTCTATCATCAACGGGTACAAACGAGTCCTGGCCTTGTCTGTGGAGACGGATTACACCTTCCCACTTGCTGAAAAGGTCAAGGCC
TTCTTGGCTGATCCATCTGCCTTTGTGGCTGCTGCCCCTGTGGCTGCTGCCACCACAGCTGCTCCTGCTGCTGCTGCAGCCCCAGCTAAG
GTTGAAGCCAAGGAAGAGTCGGAGGAGTCGGACGAGGATATGGGATTTGGTCTCTTTGACTAATCACCAAAAAGCAACCAACTTAGCCAG

>83928_83928_10_SMARCB1-RPLP0_SMARCB1_chr22_24129449_ENST00000344921_RPLP0_chr12_120635265_ENST00000546989_length(amino acids)=131AA_BP=31
MMMMALSKTFGQKPVKFQLEDDGEFYMIGSEGVRNVASVCLQIGYPTVASVPHSIINGYKRVLALSVETDYTFPLAEKVKAFLADPSAFV

--------------------------------------------------------------
>83928_83928_11_SMARCB1-RPLP0_SMARCB1_chr22_24129449_ENST00000344921_RPLP0_chr12_120635265_ENST00000551150_length(transcript)=677nt_BP=300nt
AACGCCAGCGCCTGCGCACTGAGGGCGGCCTGGTCGTCGTCTGCGGCGGCGGCGGCGGCTGAGGAGCCCGGCTGAGGCGCCAGTACCCGG
CCCGGTCCGCATTTCGCCTTCCGGCTTCGGTTTCCCTCGGCCCAGCACGCCCCGGCCCCGCCCCAGCCCTCCTGATCCCTCGCAGCCCGG
CTCCGGCCGCCCGCCTCTGCCGCCGCAATGATGATGATGGCGCTGAGCAAGACCTTCGGGCAGAAGCCCGTGAAGTTCCAGCTGGAGGAC
GACGGCGAGTTCTACATGATCGGCTCCGAGGGTGTCCGCAATGTTGCCAGTGTCTGTCTGCAGATTGGCTACCCAACTGTTGCATCAGTA
CCCCATTCTATCATCAACGGGTACAAACGAGTCCTGGCCTTGTCTGTGGAGACGGATTACACCTTCCCACTTGCTGAAAAGGTCAAGGCC
TTCTTGGCTGATCCATCTGCCTTTGTGGCTGCTGCCCCTGTGGCTGCTGCCACCACAGCTGCTCCTGCTGCTGCTGCAGCCCCAGCTAAG
GTTGAAGCCAAGGAAGAGTCGGAGGAGTCGGACGAGGATATGGGATTTGGTCTCTTTGACTAATCACCAAAAAGCAACCAACTTAGCCAG

>83928_83928_11_SMARCB1-RPLP0_SMARCB1_chr22_24129449_ENST00000344921_RPLP0_chr12_120635265_ENST00000551150_length(amino acids)=131AA_BP=31
MMMMALSKTFGQKPVKFQLEDDGEFYMIGSEGVRNVASVCLQIGYPTVASVPHSIINGYKRVLALSVETDYTFPLAEKVKAFLADPSAFV

--------------------------------------------------------------
>83928_83928_12_SMARCB1-RPLP0_SMARCB1_chr22_24129449_ENST00000344921_RPLP0_chr12_120635265_ENST00000552292_length(transcript)=674nt_BP=300nt
AACGCCAGCGCCTGCGCACTGAGGGCGGCCTGGTCGTCGTCTGCGGCGGCGGCGGCGGCTGAGGAGCCCGGCTGAGGCGCCAGTACCCGG
CCCGGTCCGCATTTCGCCTTCCGGCTTCGGTTTCCCTCGGCCCAGCACGCCCCGGCCCCGCCCCAGCCCTCCTGATCCCTCGCAGCCCGG
CTCCGGCCGCCCGCCTCTGCCGCCGCAATGATGATGATGGCGCTGAGCAAGACCTTCGGGCAGAAGCCCGTGAAGTTCCAGCTGGAGGAC
GACGGCGAGTTCTACATGATCGGCTCCGAGGTCAAGGCCTTCTTGGCTGATCCATCTGCCTTTGTGGCTGCTGCCCCTGTGGCTGCTGCC
ACCACAGCTGCTCCTGCTGCTGCTGCAGCCCCAGCTAAGGTTGAAGCCAAGGAAGAGTCGGAGGAGTCGGACGAGGATATGGGATTTGGT
CTCTTTGACTAATCACCAAAAAGCAACCAACTTAGCCAGTTTTATTTGCAAAACAAGGAAATAAAGGCTTACTTCTTTAAAAAGGTGTCC
GCAATGTTGCCAGTGTCTGTCTGCAGATTGGCTACCCAACTGTTGCATCAGTACCCCATTCTATCATCAACGGGTACAAACGAGTCCTGG

>83928_83928_12_SMARCB1-RPLP0_SMARCB1_chr22_24129449_ENST00000344921_RPLP0_chr12_120635265_ENST00000552292_length(amino acids)=84AA_BP=

--------------------------------------------------------------
>83928_83928_13_SMARCB1-RPLP0_SMARCB1_chr22_24129449_ENST00000407082_RPLP0_chr12_120635265_ENST00000228306_length(transcript)=621nt_BP=252nt
GCGGCGGCGGCTGAGGAGCCCGGCTGAGGCGCCAGTACCCGGCCCGGTCCGCATTTCGCCTTCCGGCTTCGGTTTCCCTCGGCCCAGCAC
GCCCCGGCCCCGCCCCAGCCCTCCTGATCCCTCGCAGCCCGGCTCCGGCCGCCCGCCTCTGCCGCCGCAATGATGATGATGGCGCTGAGC
AAGACCTTCGGGCAGAAGCCCGTGAAGTTCCAGCTGGAGGACGACGGCGAGTTCTACATGATCGGCTCCGAGGGTGTCCGCAATGTTGCC
AGTGTCTGTCTGCAGATTGGCTACCCAACTGTTGCATCAGTACCCCATTCTATCATCAACGGGTACAAACGAGTCCTGGCCTTGTCTGTG
GAGACGGATTACACCTTCCCACTTGCTGAAAAGGTCAAGGCCTTCTTGGCTGATCCATCTGCCTTTGTGGCTGCTGCCCCTGTGGCTGCT
GCCACCACAGCTGCTCCTGCTGCTGCTGCAGCCCCAGCTAAGGTTGAAGCCAAGGAAGAGTCGGAGGAGTCGGACGAGGATATGGGATTT

>83928_83928_13_SMARCB1-RPLP0_SMARCB1_chr22_24129449_ENST00000407082_RPLP0_chr12_120635265_ENST00000228306_length(amino acids)=131AA_BP=31
MMMMALSKTFGQKPVKFQLEDDGEFYMIGSEGVRNVASVCLQIGYPTVASVPHSIINGYKRVLALSVETDYTFPLAEKVKAFLADPSAFV

--------------------------------------------------------------
>83928_83928_14_SMARCB1-RPLP0_SMARCB1_chr22_24129449_ENST00000407082_RPLP0_chr12_120635265_ENST00000313104_length(transcript)=626nt_BP=252nt
GCGGCGGCGGCTGAGGAGCCCGGCTGAGGCGCCAGTACCCGGCCCGGTCCGCATTTCGCCTTCCGGCTTCGGTTTCCCTCGGCCCAGCAC
GCCCCGGCCCCGCCCCAGCCCTCCTGATCCCTCGCAGCCCGGCTCCGGCCGCCCGCCTCTGCCGCCGCAATGATGATGATGGCGCTGAGC
AAGACCTTCGGGCAGAAGCCCGTGAAGTTCCAGCTGGAGGACGACGGCGAGTTCTACATGATCGGCTCCGAGGGTGTCCGCAATGTTGCC
AGTGTCTGTCTGCAGATTGGCTACCCAACTGTTGCATCAGTACCCCATTCTATCATCAACGGGTACAAACGAGTCCTGGCCTTGTCTGTG
GAGACGGATTACACCTTCCCACTTGCTGAAAAGGTCAAGGCCTTCTTGGCTGATCCATCTGCCTTTGTGGCTGCTGCCCCTGTGGCTGCT
GCCACCACAGCTGCTCCTGCTGCTGCTGCAGCCCCAGCTAAGGTTGAAGCCAAGGAAGAGTCGGAGGAGTCGGACGAGGATATGGGATTT

>83928_83928_14_SMARCB1-RPLP0_SMARCB1_chr22_24129449_ENST00000407082_RPLP0_chr12_120635265_ENST00000313104_length(amino acids)=131AA_BP=31
MMMMALSKTFGQKPVKFQLEDDGEFYMIGSEGVRNVASVCLQIGYPTVASVPHSIINGYKRVLALSVETDYTFPLAEKVKAFLADPSAFV

--------------------------------------------------------------
>83928_83928_15_SMARCB1-RPLP0_SMARCB1_chr22_24129449_ENST00000407082_RPLP0_chr12_120635265_ENST00000392514_length(transcript)=642nt_BP=252nt
GCGGCGGCGGCTGAGGAGCCCGGCTGAGGCGCCAGTACCCGGCCCGGTCCGCATTTCGCCTTCCGGCTTCGGTTTCCCTCGGCCCAGCAC
GCCCCGGCCCCGCCCCAGCCCTCCTGATCCCTCGCAGCCCGGCTCCGGCCGCCCGCCTCTGCCGCCGCAATGATGATGATGGCGCTGAGC
AAGACCTTCGGGCAGAAGCCCGTGAAGTTCCAGCTGGAGGACGACGGCGAGTTCTACATGATCGGCTCCGAGGGTGTCCGCAATGTTGCC
AGTGTCTGTCTGCAGATTGGCTACCCAACTGTTGCATCAGTACCCCATTCTATCATCAACGGGTACAAACGAGTCCTGGCCTTGTCTGTG
GAGACGGATTACACCTTCCCACTTGCTGAAAAGGTCAAGGCCTTCTTGGCTGATCCATCTGCCTTTGTGGCTGCTGCCCCTGTGGCTGCT
GCCACCACAGCTGCTCCTGCTGCTGCTGCAGCCCCAGCTAAGGTTGAAGCCAAGGAAGAGTCGGAGGAGTCGGACGAGGATATGGGATTT
GGTCTCTTTGACTAATCACCAAAAAGCAACCAACTTAGCCAGTTTTATTTGCAAAACAAGGAAATAAAGGCTTACTTCTTTAAAAAGTCT

>83928_83928_15_SMARCB1-RPLP0_SMARCB1_chr22_24129449_ENST00000407082_RPLP0_chr12_120635265_ENST00000392514_length(amino acids)=131AA_BP=31
MMMMALSKTFGQKPVKFQLEDDGEFYMIGSEGVRNVASVCLQIGYPTVASVPHSIINGYKRVLALSVETDYTFPLAEKVKAFLADPSAFV

--------------------------------------------------------------
>83928_83928_16_SMARCB1-RPLP0_SMARCB1_chr22_24129449_ENST00000407082_RPLP0_chr12_120635265_ENST00000546989_length(transcript)=626nt_BP=252nt
GCGGCGGCGGCTGAGGAGCCCGGCTGAGGCGCCAGTACCCGGCCCGGTCCGCATTTCGCCTTCCGGCTTCGGTTTCCCTCGGCCCAGCAC
GCCCCGGCCCCGCCCCAGCCCTCCTGATCCCTCGCAGCCCGGCTCCGGCCGCCCGCCTCTGCCGCCGCAATGATGATGATGGCGCTGAGC
AAGACCTTCGGGCAGAAGCCCGTGAAGTTCCAGCTGGAGGACGACGGCGAGTTCTACATGATCGGCTCCGAGGGTGTCCGCAATGTTGCC
AGTGTCTGTCTGCAGATTGGCTACCCAACTGTTGCATCAGTACCCCATTCTATCATCAACGGGTACAAACGAGTCCTGGCCTTGTCTGTG
GAGACGGATTACACCTTCCCACTTGCTGAAAAGGTCAAGGCCTTCTTGGCTGATCCATCTGCCTTTGTGGCTGCTGCCCCTGTGGCTGCT
GCCACCACAGCTGCTCCTGCTGCTGCTGCAGCCCCAGCTAAGGTTGAAGCCAAGGAAGAGTCGGAGGAGTCGGACGAGGATATGGGATTT

>83928_83928_16_SMARCB1-RPLP0_SMARCB1_chr22_24129449_ENST00000407082_RPLP0_chr12_120635265_ENST00000546989_length(amino acids)=131AA_BP=31
MMMMALSKTFGQKPVKFQLEDDGEFYMIGSEGVRNVASVCLQIGYPTVASVPHSIINGYKRVLALSVETDYTFPLAEKVKAFLADPSAFV

--------------------------------------------------------------
>83928_83928_17_SMARCB1-RPLP0_SMARCB1_chr22_24129449_ENST00000407082_RPLP0_chr12_120635265_ENST00000551150_length(transcript)=629nt_BP=252nt
GCGGCGGCGGCTGAGGAGCCCGGCTGAGGCGCCAGTACCCGGCCCGGTCCGCATTTCGCCTTCCGGCTTCGGTTTCCCTCGGCCCAGCAC
GCCCCGGCCCCGCCCCAGCCCTCCTGATCCCTCGCAGCCCGGCTCCGGCCGCCCGCCTCTGCCGCCGCAATGATGATGATGGCGCTGAGC
AAGACCTTCGGGCAGAAGCCCGTGAAGTTCCAGCTGGAGGACGACGGCGAGTTCTACATGATCGGCTCCGAGGGTGTCCGCAATGTTGCC
AGTGTCTGTCTGCAGATTGGCTACCCAACTGTTGCATCAGTACCCCATTCTATCATCAACGGGTACAAACGAGTCCTGGCCTTGTCTGTG
GAGACGGATTACACCTTCCCACTTGCTGAAAAGGTCAAGGCCTTCTTGGCTGATCCATCTGCCTTTGTGGCTGCTGCCCCTGTGGCTGCT
GCCACCACAGCTGCTCCTGCTGCTGCTGCAGCCCCAGCTAAGGTTGAAGCCAAGGAAGAGTCGGAGGAGTCGGACGAGGATATGGGATTT

>83928_83928_17_SMARCB1-RPLP0_SMARCB1_chr22_24129449_ENST00000407082_RPLP0_chr12_120635265_ENST00000551150_length(amino acids)=131AA_BP=31
MMMMALSKTFGQKPVKFQLEDDGEFYMIGSEGVRNVASVCLQIGYPTVASVPHSIINGYKRVLALSVETDYTFPLAEKVKAFLADPSAFV

--------------------------------------------------------------
>83928_83928_18_SMARCB1-RPLP0_SMARCB1_chr22_24129449_ENST00000407082_RPLP0_chr12_120635265_ENST00000552292_length(transcript)=626nt_BP=252nt
GCGGCGGCGGCTGAGGAGCCCGGCTGAGGCGCCAGTACCCGGCCCGGTCCGCATTTCGCCTTCCGGCTTCGGTTTCCCTCGGCCCAGCAC
GCCCCGGCCCCGCCCCAGCCCTCCTGATCCCTCGCAGCCCGGCTCCGGCCGCCCGCCTCTGCCGCCGCAATGATGATGATGGCGCTGAGC
AAGACCTTCGGGCAGAAGCCCGTGAAGTTCCAGCTGGAGGACGACGGCGAGTTCTACATGATCGGCTCCGAGGTCAAGGCCTTCTTGGCT
GATCCATCTGCCTTTGTGGCTGCTGCCCCTGTGGCTGCTGCCACCACAGCTGCTCCTGCTGCTGCTGCAGCCCCAGCTAAGGTTGAAGCC
AAGGAAGAGTCGGAGGAGTCGGACGAGGATATGGGATTTGGTCTCTTTGACTAATCACCAAAAAGCAACCAACTTAGCCAGTTTTATTTG
CAAAACAAGGAAATAAAGGCTTACTTCTTTAAAAAGGTGTCCGCAATGTTGCCAGTGTCTGTCTGCAGATTGGCTACCCAACTGTTGCAT

>83928_83928_18_SMARCB1-RPLP0_SMARCB1_chr22_24129449_ENST00000407082_RPLP0_chr12_120635265_ENST00000552292_length(amino acids)=84AA_BP=

--------------------------------------------------------------
>83928_83928_19_SMARCB1-RPLP0_SMARCB1_chr22_24129449_ENST00000407422_RPLP0_chr12_120635265_ENST00000228306_length(transcript)=638nt_BP=269nt
GGTCGTCGTCTGCGGCGGCGGCGGCGGCTGAGGAGCCCGGCTGAGGCGCCAGTACCCGGCCCGGTCCGCATTTCGCCTTCCGGCTTCGGT
TTCCCTCGGCCCAGCACGCCCCGGCCCCGCCCCAGCCCTCCTGATCCCTCGCAGCCCGGCTCCGGCCGCCCGCCTCTGCCGCCGCAATGA
TGATGATGGCGCTGAGCAAGACCTTCGGGCAGAAGCCCGTGAAGTTCCAGCTGGAGGACGACGGCGAGTTCTACATGATCGGCTCCGAGG
GTGTCCGCAATGTTGCCAGTGTCTGTCTGCAGATTGGCTACCCAACTGTTGCATCAGTACCCCATTCTATCATCAACGGGTACAAACGAG
TCCTGGCCTTGTCTGTGGAGACGGATTACACCTTCCCACTTGCTGAAAAGGTCAAGGCCTTCTTGGCTGATCCATCTGCCTTTGTGGCTG
CTGCCCCTGTGGCTGCTGCCACCACAGCTGCTCCTGCTGCTGCTGCAGCCCCAGCTAAGGTTGAAGCCAAGGAAGAGTCGGAGGAGTCGG
ACGAGGATATGGGATTTGGTCTCTTTGACTAATCACCAAAAAGCAACCAACTTAGCCAGTTTTATTTGCAAAACAAGGAAATAAAGGCTT

>83928_83928_19_SMARCB1-RPLP0_SMARCB1_chr22_24129449_ENST00000407422_RPLP0_chr12_120635265_ENST00000228306_length(amino acids)=131AA_BP=31
MMMMALSKTFGQKPVKFQLEDDGEFYMIGSEGVRNVASVCLQIGYPTVASVPHSIINGYKRVLALSVETDYTFPLAEKVKAFLADPSAFV

--------------------------------------------------------------
>83928_83928_20_SMARCB1-RPLP0_SMARCB1_chr22_24129449_ENST00000407422_RPLP0_chr12_120635265_ENST00000313104_length(transcript)=643nt_BP=269nt
GGTCGTCGTCTGCGGCGGCGGCGGCGGCTGAGGAGCCCGGCTGAGGCGCCAGTACCCGGCCCGGTCCGCATTTCGCCTTCCGGCTTCGGT
TTCCCTCGGCCCAGCACGCCCCGGCCCCGCCCCAGCCCTCCTGATCCCTCGCAGCCCGGCTCCGGCCGCCCGCCTCTGCCGCCGCAATGA
TGATGATGGCGCTGAGCAAGACCTTCGGGCAGAAGCCCGTGAAGTTCCAGCTGGAGGACGACGGCGAGTTCTACATGATCGGCTCCGAGG
GTGTCCGCAATGTTGCCAGTGTCTGTCTGCAGATTGGCTACCCAACTGTTGCATCAGTACCCCATTCTATCATCAACGGGTACAAACGAG
TCCTGGCCTTGTCTGTGGAGACGGATTACACCTTCCCACTTGCTGAAAAGGTCAAGGCCTTCTTGGCTGATCCATCTGCCTTTGTGGCTG
CTGCCCCTGTGGCTGCTGCCACCACAGCTGCTCCTGCTGCTGCTGCAGCCCCAGCTAAGGTTGAAGCCAAGGAAGAGTCGGAGGAGTCGG
ACGAGGATATGGGATTTGGTCTCTTTGACTAATCACCAAAAAGCAACCAACTTAGCCAGTTTTATTTGCAAAACAAGGAAATAAAGGCTT

>83928_83928_20_SMARCB1-RPLP0_SMARCB1_chr22_24129449_ENST00000407422_RPLP0_chr12_120635265_ENST00000313104_length(amino acids)=131AA_BP=31
MMMMALSKTFGQKPVKFQLEDDGEFYMIGSEGVRNVASVCLQIGYPTVASVPHSIINGYKRVLALSVETDYTFPLAEKVKAFLADPSAFV

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>83928_83928_21_SMARCB1-RPLP0_SMARCB1_chr22_24129449_ENST00000407422_RPLP0_chr12_120635265_ENST00000392514_length(transcript)=659nt_BP=269nt
GGTCGTCGTCTGCGGCGGCGGCGGCGGCTGAGGAGCCCGGCTGAGGCGCCAGTACCCGGCCCGGTCCGCATTTCGCCTTCCGGCTTCGGT
TTCCCTCGGCCCAGCACGCCCCGGCCCCGCCCCAGCCCTCCTGATCCCTCGCAGCCCGGCTCCGGCCGCCCGCCTCTGCCGCCGCAATGA
TGATGATGGCGCTGAGCAAGACCTTCGGGCAGAAGCCCGTGAAGTTCCAGCTGGAGGACGACGGCGAGTTCTACATGATCGGCTCCGAGG
GTGTCCGCAATGTTGCCAGTGTCTGTCTGCAGATTGGCTACCCAACTGTTGCATCAGTACCCCATTCTATCATCAACGGGTACAAACGAG
TCCTGGCCTTGTCTGTGGAGACGGATTACACCTTCCCACTTGCTGAAAAGGTCAAGGCCTTCTTGGCTGATCCATCTGCCTTTGTGGCTG
CTGCCCCTGTGGCTGCTGCCACCACAGCTGCTCCTGCTGCTGCTGCAGCCCCAGCTAAGGTTGAAGCCAAGGAAGAGTCGGAGGAGTCGG
ACGAGGATATGGGATTTGGTCTCTTTGACTAATCACCAAAAAGCAACCAACTTAGCCAGTTTTATTTGCAAAACAAGGAAATAAAGGCTT

>83928_83928_21_SMARCB1-RPLP0_SMARCB1_chr22_24129449_ENST00000407422_RPLP0_chr12_120635265_ENST00000392514_length(amino acids)=131AA_BP=31
MMMMALSKTFGQKPVKFQLEDDGEFYMIGSEGVRNVASVCLQIGYPTVASVPHSIINGYKRVLALSVETDYTFPLAEKVKAFLADPSAFV

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>83928_83928_22_SMARCB1-RPLP0_SMARCB1_chr22_24129449_ENST00000407422_RPLP0_chr12_120635265_ENST00000546989_length(transcript)=643nt_BP=269nt
GGTCGTCGTCTGCGGCGGCGGCGGCGGCTGAGGAGCCCGGCTGAGGCGCCAGTACCCGGCCCGGTCCGCATTTCGCCTTCCGGCTTCGGT
TTCCCTCGGCCCAGCACGCCCCGGCCCCGCCCCAGCCCTCCTGATCCCTCGCAGCCCGGCTCCGGCCGCCCGCCTCTGCCGCCGCAATGA
TGATGATGGCGCTGAGCAAGACCTTCGGGCAGAAGCCCGTGAAGTTCCAGCTGGAGGACGACGGCGAGTTCTACATGATCGGCTCCGAGG
GTGTCCGCAATGTTGCCAGTGTCTGTCTGCAGATTGGCTACCCAACTGTTGCATCAGTACCCCATTCTATCATCAACGGGTACAAACGAG
TCCTGGCCTTGTCTGTGGAGACGGATTACACCTTCCCACTTGCTGAAAAGGTCAAGGCCTTCTTGGCTGATCCATCTGCCTTTGTGGCTG
CTGCCCCTGTGGCTGCTGCCACCACAGCTGCTCCTGCTGCTGCTGCAGCCCCAGCTAAGGTTGAAGCCAAGGAAGAGTCGGAGGAGTCGG
ACGAGGATATGGGATTTGGTCTCTTTGACTAATCACCAAAAAGCAACCAACTTAGCCAGTTTTATTTGCAAAACAAGGAAATAAAGGCTT

>83928_83928_22_SMARCB1-RPLP0_SMARCB1_chr22_24129449_ENST00000407422_RPLP0_chr12_120635265_ENST00000546989_length(amino acids)=131AA_BP=31
MMMMALSKTFGQKPVKFQLEDDGEFYMIGSEGVRNVASVCLQIGYPTVASVPHSIINGYKRVLALSVETDYTFPLAEKVKAFLADPSAFV

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>83928_83928_23_SMARCB1-RPLP0_SMARCB1_chr22_24129449_ENST00000407422_RPLP0_chr12_120635265_ENST00000551150_length(transcript)=646nt_BP=269nt
GGTCGTCGTCTGCGGCGGCGGCGGCGGCTGAGGAGCCCGGCTGAGGCGCCAGTACCCGGCCCGGTCCGCATTTCGCCTTCCGGCTTCGGT
TTCCCTCGGCCCAGCACGCCCCGGCCCCGCCCCAGCCCTCCTGATCCCTCGCAGCCCGGCTCCGGCCGCCCGCCTCTGCCGCCGCAATGA
TGATGATGGCGCTGAGCAAGACCTTCGGGCAGAAGCCCGTGAAGTTCCAGCTGGAGGACGACGGCGAGTTCTACATGATCGGCTCCGAGG
GTGTCCGCAATGTTGCCAGTGTCTGTCTGCAGATTGGCTACCCAACTGTTGCATCAGTACCCCATTCTATCATCAACGGGTACAAACGAG
TCCTGGCCTTGTCTGTGGAGACGGATTACACCTTCCCACTTGCTGAAAAGGTCAAGGCCTTCTTGGCTGATCCATCTGCCTTTGTGGCTG
CTGCCCCTGTGGCTGCTGCCACCACAGCTGCTCCTGCTGCTGCTGCAGCCCCAGCTAAGGTTGAAGCCAAGGAAGAGTCGGAGGAGTCGG
ACGAGGATATGGGATTTGGTCTCTTTGACTAATCACCAAAAAGCAACCAACTTAGCCAGTTTTATTTGCAAAACAAGGAAATAAAGGCTT

>83928_83928_23_SMARCB1-RPLP0_SMARCB1_chr22_24129449_ENST00000407422_RPLP0_chr12_120635265_ENST00000551150_length(amino acids)=131AA_BP=31
MMMMALSKTFGQKPVKFQLEDDGEFYMIGSEGVRNVASVCLQIGYPTVASVPHSIINGYKRVLALSVETDYTFPLAEKVKAFLADPSAFV

--------------------------------------------------------------
>83928_83928_24_SMARCB1-RPLP0_SMARCB1_chr22_24129449_ENST00000407422_RPLP0_chr12_120635265_ENST00000552292_length(transcript)=643nt_BP=269nt
GGTCGTCGTCTGCGGCGGCGGCGGCGGCTGAGGAGCCCGGCTGAGGCGCCAGTACCCGGCCCGGTCCGCATTTCGCCTTCCGGCTTCGGT
TTCCCTCGGCCCAGCACGCCCCGGCCCCGCCCCAGCCCTCCTGATCCCTCGCAGCCCGGCTCCGGCCGCCCGCCTCTGCCGCCGCAATGA
TGATGATGGCGCTGAGCAAGACCTTCGGGCAGAAGCCCGTGAAGTTCCAGCTGGAGGACGACGGCGAGTTCTACATGATCGGCTCCGAGG
TCAAGGCCTTCTTGGCTGATCCATCTGCCTTTGTGGCTGCTGCCCCTGTGGCTGCTGCCACCACAGCTGCTCCTGCTGCTGCTGCAGCCC
CAGCTAAGGTTGAAGCCAAGGAAGAGTCGGAGGAGTCGGACGAGGATATGGGATTTGGTCTCTTTGACTAATCACCAAAAAGCAACCAAC
TTAGCCAGTTTTATTTGCAAAACAAGGAAATAAAGGCTTACTTCTTTAAAAAGGTGTCCGCAATGTTGCCAGTGTCTGTCTGCAGATTGG
CTACCCAACTGTTGCATCAGTACCCCATTCTATCATCAACGGGTACAAACGAGTCCTGGCCTTGTCTGTGGAGACGGATTACACCTTCCC

>83928_83928_24_SMARCB1-RPLP0_SMARCB1_chr22_24129449_ENST00000407422_RPLP0_chr12_120635265_ENST00000552292_length(amino acids)=84AA_BP=

--------------------------------------------------------------

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Fusion Gene PPI Analysis for SMARCB1-RPLP0


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with
HgeneSMARCB1chr22:24129449chr12:120635265ENST00000263121+19304_31831.0386.0PPP1R15A
HgeneSMARCB1chr22:24129449chr12:120635265ENST00000407422+19304_31831.0377.0PPP1R15A


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for SMARCB1-RPLP0


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for SMARCB1-RPLP0


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource