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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:SMARCB1-SNW1 (FusionGDB2 ID:83932)

Fusion Gene Summary for SMARCB1-SNW1

check button Fusion gene summary
Fusion gene informationFusion gene name: SMARCB1-SNW1
Fusion gene ID: 83932
HgeneTgene
Gene symbol

SMARCB1

SNW1

Gene ID

6598

22938

Gene nameSWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1SNW domain containing 1
SynonymsBAF47|CSS3|INI1|MRD15|PPP1R144|RDT|RTPS1|SNF5|SNF5L1|SWNTS1|Sfh1p|Snr1|hSNFSBx42|FUN20|NCOA-62|PRPF45|Prp45|SKIIP|SKIP|SKIP1
Cytomap

22q11.23|22q11

14q24.3

Type of geneprotein-codingprotein-coding
DescriptionSWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1BRG1-associated factor 47SNF5 homologSWI/SNF-related matrix-associated proteinhSNF5integrase interactor 1 proteinmalignant rhabdoid tumor suppressorproteinSNW domain-containing protein 1SKI interacting proteinhomolog of Drosophila BX42nuclear protein SkiPnuclear receptor coactivator NCoA-62nuclear receptor coactivator, 62-kDski-interacting protein
Modification date2020031320200313
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000263121, ENST00000344921, 
ENST00000407082, ENST00000407422, 
ENST00000477836, 		ENST00000261531, 
ENST00000554775, ENST00000555761, 
Fusion gene scores* DoF score14 X 15 X 8=168020 X 9 X 11=1980
# samples 1922
** MAII scorelog2(19/1680*10)=-3.14438990933518
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(22/1980*10)=-3.16992500144231
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: SMARCB1 [Title/Abstract] AND SNW1 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointSMARCB1(24129449)-SNW1(78201355), # samples:3
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneSMARCB1

GO:0006337

nucleosome disassembly

8895581

HgeneSMARCB1

GO:0006338

chromatin remodeling

11726552

HgeneSMARCB1

GO:0039692

single stranded viral RNA replication via double stranded DNA intermediate

14963118

HgeneSMARCB1

GO:0045944

positive regulation of transcription by RNA polymerase II

11950834

HgeneSMARCB1

GO:0051091

positive regulation of DNA-binding transcription factor activity

11950834

HgeneSMARCB1

GO:1902661

positive regulation of glucose mediated signaling pathway

22368283

TgeneSNW1

GO:0000122

negative regulation of transcription by RNA polymerase II

14985122

TgeneSNW1

GO:0000398

mRNA splicing, via spliceosome

15194481|28076346

TgeneSNW1

GO:0030511

positive regulation of transforming growth factor beta receptor signaling pathway

11278756

TgeneSNW1

GO:0043923

positive regulation by host of viral transcription

15905409

TgeneSNW1

GO:0045892

negative regulation of transcription, DNA-templated

10713164|15878163

TgeneSNW1

GO:0045944

positive regulation of transcription by RNA polymerase II

14985122|19934264

TgeneSNW1

GO:0048384

retinoic acid receptor signaling pathway

19934264

TgeneSNW1

GO:0048385

regulation of retinoic acid receptor signaling pathway

14985122

TgeneSNW1

GO:0070562

regulation of vitamin D receptor signaling pathway

14985122

TgeneSNW1

GO:0070564

positive regulation of vitamin D receptor signaling pathway

9632709|11514567

TgeneSNW1

GO:0071300

cellular response to retinoic acid

19934264


check buttonFusion gene breakpoints across SMARCB1 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across SNW1 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4BLCATCGA-UY-A9PE-01ASMARCB1chr22

24129449

-SNW1chr14

78201355

-
ChimerDB4BLCATCGA-UY-A9PE-01ASMARCB1chr22

24129449

+SNW1chr14

78201355

-


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Fusion Gene ORF analysis for SMARCB1-SNW1

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
In-frameENST00000263121ENST00000261531SMARCB1chr22

24129449

+SNW1chr14

78201355

-
In-frameENST00000263121ENST00000554775SMARCB1chr22

24129449

+SNW1chr14

78201355

-
In-frameENST00000263121ENST00000555761SMARCB1chr22

24129449

+SNW1chr14

78201355

-
In-frameENST00000344921ENST00000261531SMARCB1chr22

24129449

+SNW1chr14

78201355

-
In-frameENST00000344921ENST00000554775SMARCB1chr22

24129449

+SNW1chr14

78201355

-
In-frameENST00000344921ENST00000555761SMARCB1chr22

24129449

+SNW1chr14

78201355

-
In-frameENST00000407082ENST00000261531SMARCB1chr22

24129449

+SNW1chr14

78201355

-
In-frameENST00000407082ENST00000554775SMARCB1chr22

24129449

+SNW1chr14

78201355

-
In-frameENST00000407082ENST00000555761SMARCB1chr22

24129449

+SNW1chr14

78201355

-
In-frameENST00000407422ENST00000261531SMARCB1chr22

24129449

+SNW1chr14

78201355

-
In-frameENST00000407422ENST00000554775SMARCB1chr22

24129449

+SNW1chr14

78201355

-
In-frameENST00000407422ENST00000555761SMARCB1chr22

24129449

+SNW1chr14

78201355

-
intron-3CDSENST00000477836ENST00000261531SMARCB1chr22

24129449

+SNW1chr14

78201355

-
intron-3CDSENST00000477836ENST00000554775SMARCB1chr22

24129449

+SNW1chr14

78201355

-
intron-3CDSENST00000477836ENST00000555761SMARCB1chr22

24129449

+SNW1chr14

78201355

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000344921SMARCB1chr2224129449+ENST00000261531SNW1chr1478201355-16923002071202331
ENST00000344921SMARCB1chr2224129449+ENST00000554775SNW1chr1478201355-16633002071202331
ENST00000344921SMARCB1chr2224129449+ENST00000555761SNW1chr1478201355-14183002071307366
ENST00000263121SMARCB1chr2224129449+ENST00000261531SNW1chr1478201355-16812891961191331
ENST00000263121SMARCB1chr2224129449+ENST00000554775SNW1chr1478201355-16522891961191331
ENST00000263121SMARCB1chr2224129449+ENST00000555761SNW1chr1478201355-14072891961296366
ENST00000407422SMARCB1chr2224129449+ENST00000261531SNW1chr1478201355-16612691761171331
ENST00000407422SMARCB1chr2224129449+ENST00000554775SNW1chr1478201355-16322691761171331
ENST00000407422SMARCB1chr2224129449+ENST00000555761SNW1chr1478201355-13872691761276366
ENST00000407082SMARCB1chr2224129449+ENST00000261531SNW1chr1478201355-16442521591154331
ENST00000407082SMARCB1chr2224129449+ENST00000554775SNW1chr1478201355-16152521591154331
ENST00000407082SMARCB1chr2224129449+ENST00000555761SNW1chr1478201355-13702521591259366

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000344921ENST00000261531SMARCB1chr2224129449+SNW1chr1478201355-0.0003872650.99961275
ENST00000344921ENST00000554775SMARCB1chr2224129449+SNW1chr1478201355-0.0004229420.9995771
ENST00000344921ENST00000555761SMARCB1chr2224129449+SNW1chr1478201355-0.001096370.99890363
ENST00000263121ENST00000261531SMARCB1chr2224129449+SNW1chr1478201355-0.0003786950.9996213
ENST00000263121ENST00000554775SMARCB1chr2224129449+SNW1chr1478201355-0.0004204780.9995795
ENST00000263121ENST00000555761SMARCB1chr2224129449+SNW1chr1478201355-0.0010656630.9989343
ENST00000407422ENST00000261531SMARCB1chr2224129449+SNW1chr1478201355-0.0003647440.9996352
ENST00000407422ENST00000554775SMARCB1chr2224129449+SNW1chr1478201355-0.0004093690.9995907
ENST00000407422ENST00000555761SMARCB1chr2224129449+SNW1chr1478201355-0.0010584150.9989416
ENST00000407082ENST00000261531SMARCB1chr2224129449+SNW1chr1478201355-0.0003786730.9996213
ENST00000407082ENST00000554775SMARCB1chr2224129449+SNW1chr1478201355-0.0004125620.9995875
ENST00000407082ENST00000555761SMARCB1chr2224129449+SNW1chr1478201355-0.0010664360.9989336

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Fusion Genomic Features for SMARCB1-SNW1


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for SMARCB1-SNW1


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr22:24129449/chr14:78201355)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneSMARCB1chr22:24129449chr14:78201355ENST00000263121+19183_24331386.0RegionNote=HIV-1 integrase-binding
HgeneSMARCB1chr22:24129449chr14:78201355ENST00000263121+19186_24531386.0RegionMYC-binding
HgeneSMARCB1chr22:24129449chr14:78201355ENST00000263121+19186_31931386.0RegionNote=2 X approximate tandem repeats
HgeneSMARCB1chr22:24129449chr14:78201355ENST00000263121+191_11331386.0RegionDNA-binding
HgeneSMARCB1chr22:24129449chr14:78201355ENST00000407422+19183_24331377.0RegionNote=HIV-1 integrase-binding
HgeneSMARCB1chr22:24129449chr14:78201355ENST00000407422+19186_24531377.0RegionMYC-binding
HgeneSMARCB1chr22:24129449chr14:78201355ENST00000407422+19186_31931377.0RegionNote=2 X approximate tandem repeats
HgeneSMARCB1chr22:24129449chr14:78201355ENST00000407422+191_11331377.0RegionDNA-binding
HgeneSMARCB1chr22:24129449chr14:78201355ENST00000263121+19259_31931386.0RepeatNote=2
HgeneSMARCB1chr22:24129449chr14:78201355ENST00000407422+19259_31931377.0RepeatNote=2
TgeneSNW1chr22:24129449chr14:78201355ENST00000261531614219_233236537.0Compositional biasNote=Pro-rich
TgeneSNW1chr22:24129449chr14:78201355ENST00000261531614174_339236537.0RegionNote=SNW


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Fusion Gene Sequence for SMARCB1-SNW1


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>83932_83932_1_SMARCB1-SNW1_SMARCB1_chr22_24129449_ENST00000263121_SNW1_chr14_78201355_ENST00000261531_length(transcript)=1681nt_BP=289nt
CTGCGCACTGAGGGCGGCCTGGTCGTCGTCTGCGGCGGCGGCGGCGGCTGAGGAGCCCGGCTGAGGCGCCAGTACCCGGCCCGGTCCGCA
TTTCGCCTTCCGGCTTCGGTTTCCCTCGGCCCAGCACGCCCCGGCCCCGCCCCAGCCCTCCTGATCCCTCGCAGCCCGGCTCCGGCCGCC
CGCCTCTGCCGCCGCAATGATGATGATGGCGCTGAGCAAGACCTTCGGGCAGAAGCCCGTGAAGTTCCAGCTGGAGGACGACGGCGAGTT
CTACATGATCGGCTCCGAGATGACTGTAAAGGAACAACAAGAGTGGAAGATTCCTCCTTGTATTTCTAACTGGAAAAATGCAAAGGGTTA
TACAATTCCATTAGACAAACGTCTGGCTGCTGATGGAAGAGGACTACAGACAGTACACATAAATGAAAATTTCGCCAAATTGGCAGAAGC
CCTCTACATTGCTGATCGGAAGGCTCGTGAAGCTGTGGAAATGCGTGCCCAAGTAGAGAGAAAAATGGCTCAGAAAGAAAAGGAAAAACA
TGAAGAGAAACTTAGAGAAATGGCCCAGAAAGCCAGGGAGAGAAGAGCTGGGATCAAAACTCATGTGGAAAAAGAGGATGGGGAGGCACG
TGAGAGGGATGAAATCCGGCATGACAGGCGAAAAGAGAGACAGCATGACCGGAATCTTTCCAGGGCAGCTCCTGATAAGAGGTCGAAACT
TCAGAGAAATGAAAATCGGGATATCAGTGAAGTTATTGCTCTCGGTGTTCCTAATCCTCGGACTTCCAATGAAGTTCAGTATGACCAAAG
GCTCTTCAACCAATCCAAGGGTATGGACAGTGGATTTGCAGGTGGAGAAGATGAAATTTATAATGTTTATGATCAAGCCTGGAGAGGTGG
TAAAGATATGGCCCAGAGTATTTATAGGCCCAGTAAAAATCTGGACAAGGACATGTATGGTGATGACCTAGAAGCCAGAATAAAGACCAA
CAGATTTGTTCCCGACAAGGAGTTTTCTGGTTCAGACCGTAGACAGAGAGGCCGAGAAGGACCAGTGCAGTTTGAGGAAGATCCTTTTGG
TTTGGACAAGTTTTTGGAAGAAGCCAAACAGCATGGTGGCTCTAAAAGACCCTCAGATAGCAGCCGCCCCAAGGAACACGAGCATGAAGG
CAAGAAGAGGAGGAAGGAATAGGCACAGGTCTCTCCAAAGTGAATGAACTCTTACCCATAACCCTAATGATGCAAGTCATATGGGGGAAC
ACTTTGTAAATGGTCAGGATAAAAACCAAATCTGGGTGCCAGATCCCAGCACTACTTTTTATTACTGGAGAAATGGGGGGGATAGAAAAT
TCTACTTTGAATTATTTAGTTTTTTTTAAAGAGTGGGTTGTGTTTGTGCTTCTCCCACCTTTCAGCATTTATAGAACATGCTGCCCCACA
TACAAAGTCAAGACCACTTACTTTTATGTGACACTAGTAGTTTGGGGTTAATGTTTTGTGTAAGAACAGCTGCATATGAGTAAAGTTACC
CCAACCACAGTGAGGAGGAAGATGTTCACATACTGGAACTGTCCTGCCAAATAAATTTTGCCCCTATTGTGCTCTGTTTTAATTTGGAGT

>83932_83932_1_SMARCB1-SNW1_SMARCB1_chr22_24129449_ENST00000263121_SNW1_chr14_78201355_ENST00000261531_length(amino acids)=331AA_BP=29
MMMMALSKTFGQKPVKFQLEDDGEFYMIGSEMTVKEQQEWKIPPCISNWKNAKGYTIPLDKRLAADGRGLQTVHINENFAKLAEALYIAD
RKAREAVEMRAQVERKMAQKEKEKHEEKLREMAQKARERRAGIKTHVEKEDGEARERDEIRHDRRKERQHDRNLSRAAPDKRSKLQRNEN
RDISEVIALGVPNPRTSNEVQYDQRLFNQSKGMDSGFAGGEDEIYNVYDQAWRGGKDMAQSIYRPSKNLDKDMYGDDLEARIKTNRFVPD

--------------------------------------------------------------
>83932_83932_2_SMARCB1-SNW1_SMARCB1_chr22_24129449_ENST00000263121_SNW1_chr14_78201355_ENST00000554775_length(transcript)=1652nt_BP=289nt
CTGCGCACTGAGGGCGGCCTGGTCGTCGTCTGCGGCGGCGGCGGCGGCTGAGGAGCCCGGCTGAGGCGCCAGTACCCGGCCCGGTCCGCA
TTTCGCCTTCCGGCTTCGGTTTCCCTCGGCCCAGCACGCCCCGGCCCCGCCCCAGCCCTCCTGATCCCTCGCAGCCCGGCTCCGGCCGCC
CGCCTCTGCCGCCGCAATGATGATGATGGCGCTGAGCAAGACCTTCGGGCAGAAGCCCGTGAAGTTCCAGCTGGAGGACGACGGCGAGTT
CTACATGATCGGCTCCGAGATGACTGTAAAGGAACAACAAGAGTGGAAGATTCCTCCTTGTATTTCTAACTGGAAAAATGCAAAGGGTTA
TACAATTCCATTAGACAAACGTCTGGCTGCTGATGGAAGAGGACTACAGACAGTACACATAAATGAAAATTTCGCCAAATTGGCAGAAGC
CCTCTACATTGCTGATCGGAAGGCTCGTGAAGCTGTGGAAATGCGTGCCCAAGTAGAGAGAAAAATGGCTCAGAAAGAAAAGGAAAAACA
TGAAGAGAAACTTAGAGAAATGGCCCAGAAAGCCAGGGAGAGAAGAGCTGGGATCAAAACTCATGTGGAAAAAGAGGATGGGGAGGCACG
TGAGAGGGATGAAATCCGGCATGACAGGCGAAAAGAGAGACAGCATGACCGGAATCTTTCCAGGGCAGCTCCTGATAAGAGGTCGAAACT
TCAGAGAAATGAAAATCGGGATATCAGTGAAGTTATTGCTCTCGGTGTTCCTAATCCTCGGACTTCCAATGAAGTTCAGTATGACCAAAG
GCTCTTCAACCAATCCAAGGGTATGGACAGTGGATTTGCAGGTGGAGAAGATGAAATTTATAATGTTTATGATCAAGCCTGGAGAGGTGG
TAAAGATATGGCCCAGAGTATTTATAGGCCCAGTAAAAATCTGGACAAGGACATGTATGGTGATGACCTAGAAGCCAGAATAAAGACCAA
CAGATTTGTTCCCGACAAGGAGTTTTCTGGTTCAGACCGTAGACAGAGAGGCCGAGAAGGACCAGTGCAGTTTGAGGAAGATCCTTTTGG
TTTGGACAAGTTTTTGGAAGAAGCCAAACAGCATGGTGGCTCTAAAAGACCCTCAGATAGCAGCCGCCCCAAGGAACACGAGCATGAAGG
CAAGAAGAGGAGGAAGGAATAGGCACAGGTCTCTCCAAAGTGAATGAACTCTTACCCATAACCCTAATGATGCAAGTCATATGGGGGAAC
ACTTTGTAAATGGTCAGGATAAAAACCAAATCTGGGTGCCAGATCCCAGCACTACTTTTTATTACTGGAGAAATGGGGGGGATAGAAAAT
TCTACTTTGAATTATTTAGTTTTTTTTAAAGAGTGGGTTGTGTTTGTGCTTCTCCCACCTTTCAGCATTTATAGAACATGCTGCCCCACA
TACAAAGTCAAGACCACTTACTTTTATGTGACACTAGTAGTTTGGGGTTAATGTTTTGTGTAAGAACAGCTGCATATGAGTAAAGTTACC
CCAACCACAGTGAGGAGGAAGATGTTCACATACTGGAACTGTCCTGCCAAATAAATTTTGCCCCTATTGTGCTCTGTTTTAATTTGGAGT

>83932_83932_2_SMARCB1-SNW1_SMARCB1_chr22_24129449_ENST00000263121_SNW1_chr14_78201355_ENST00000554775_length(amino acids)=331AA_BP=29
MMMMALSKTFGQKPVKFQLEDDGEFYMIGSEMTVKEQQEWKIPPCISNWKNAKGYTIPLDKRLAADGRGLQTVHINENFAKLAEALYIAD
RKAREAVEMRAQVERKMAQKEKEKHEEKLREMAQKARERRAGIKTHVEKEDGEARERDEIRHDRRKERQHDRNLSRAAPDKRSKLQRNEN
RDISEVIALGVPNPRTSNEVQYDQRLFNQSKGMDSGFAGGEDEIYNVYDQAWRGGKDMAQSIYRPSKNLDKDMYGDDLEARIKTNRFVPD

--------------------------------------------------------------
>83932_83932_3_SMARCB1-SNW1_SMARCB1_chr22_24129449_ENST00000263121_SNW1_chr14_78201355_ENST00000555761_length(transcript)=1407nt_BP=289nt
CTGCGCACTGAGGGCGGCCTGGTCGTCGTCTGCGGCGGCGGCGGCGGCTGAGGAGCCCGGCTGAGGCGCCAGTACCCGGCCCGGTCCGCA
TTTCGCCTTCCGGCTTCGGTTTCCCTCGGCCCAGCACGCCCCGGCCCCGCCCCAGCCCTCCTGATCCCTCGCAGCCCGGCTCCGGCCGCC
CGCCTCTGCCGCCGCAATGATGATGATGGCGCTGAGCAAGACCTTCGGGCAGAAGCCCGTGAAGTTCCAGCTGGAGGACGACGGCGAGTT
CTACATGATCGGCTCCGAGATGACTGTAAAGGAACAACAAGAGTGGAAGATTCCTCCTTGTATTTCTAACTGGAAAAATGCAAAGGGTTA
TACAATTCCATTAGACAAACGTCTGGCTGCTGATGGAAGAGGACTACAGACAGTACACATAAATGAAAATTTCGCCAAATTGGCAGAAGC
CCTCTACATTGCTGATCGGAAGGCTCGTGAAGCTGTGGAAATGCGTGCCCAAGTAGAGAGAAAAATGGCTCAGAAAGAAAAGGAAAAACA
TGAAGAGAAACTTAGAGAAATGGCCCAGAAAGCCAGGGAGAGAAGAGCTGGGATCAAAACTCATGTGGAAAAAGAGGATGGGGAGGCACG
TGAGAGGGATGAAATCCGGCATGACAGGCGAAAAGAGAGACAGCATGACCGGAATCTTTCCAGGGCAGCTCCTGATAAGAGGTCGAAACT
TCAGAGAAATGAAAATCGGGATATCAGTGAAGTTATTGCTCTCGGTGTTCCTAATCCTCGGACTTCCAATGAAGTTCAGTATGACCAAAG
GCTCTTCAACCAATCCAAGGGTATGGACAGTGGATTTGCAGGTGGAGAAGATGAAATTTATAATGTTTATGATCAAGCCTGGAGAGGTGG
TAAAGATATGGCCCAGAGTATTTATAGGCCCAGTAAAAATCTGGACAAGGACATGTATGGTGATGACCTAGAAGCCAGAATAAAGACCAA
CAGGTGCCAAGCCATACAACTCAATTTCAGTGTTTACACTGGTGAAAGCAAAGTAGTTCATAGTTTTTTCTCCTTTTCCTTAGATTTGTT
CCCGACAAGGAGTTTTCTGGTTCAGACCGTAGACAGAGAGGCCGAGAAGGACCAGTGCAGTTTGAGGAAGATCCTTTTGGTTTGGACAAG
TTTTTGGAAGAAGCCAAACAGCATGGTGGCTCTAAAAGACCCTCAGATAGCAGCCGCCCCAAGGAACACGAGCATGAAGGCAAGAAGAGG
AGGAAGGAATAGGCACAGGTCTCTCCAAAGTGAATGAACTCTTACCCATAACCCTAATGATGCAAGTCATATGGGGGAACACTTTGTAAA

>83932_83932_3_SMARCB1-SNW1_SMARCB1_chr22_24129449_ENST00000263121_SNW1_chr14_78201355_ENST00000555761_length(amino acids)=366AA_BP=29
MMMMALSKTFGQKPVKFQLEDDGEFYMIGSEMTVKEQQEWKIPPCISNWKNAKGYTIPLDKRLAADGRGLQTVHINENFAKLAEALYIAD
RKAREAVEMRAQVERKMAQKEKEKHEEKLREMAQKARERRAGIKTHVEKEDGEARERDEIRHDRRKERQHDRNLSRAAPDKRSKLQRNEN
RDISEVIALGVPNPRTSNEVQYDQRLFNQSKGMDSGFAGGEDEIYNVYDQAWRGGKDMAQSIYRPSKNLDKDMYGDDLEARIKTNRCQAI
QLNFSVYTGESKVVHSFFSFSLDLFPTRSFLVQTVDREAEKDQCSLRKILLVWTSFWKKPNSMVALKDPQIAAAPRNTSMKARRGGRNRH

--------------------------------------------------------------
>83932_83932_4_SMARCB1-SNW1_SMARCB1_chr22_24129449_ENST00000344921_SNW1_chr14_78201355_ENST00000261531_length(transcript)=1692nt_BP=300nt
AACGCCAGCGCCTGCGCACTGAGGGCGGCCTGGTCGTCGTCTGCGGCGGCGGCGGCGGCTGAGGAGCCCGGCTGAGGCGCCAGTACCCGG
CCCGGTCCGCATTTCGCCTTCCGGCTTCGGTTTCCCTCGGCCCAGCACGCCCCGGCCCCGCCCCAGCCCTCCTGATCCCTCGCAGCCCGG
CTCCGGCCGCCCGCCTCTGCCGCCGCAATGATGATGATGGCGCTGAGCAAGACCTTCGGGCAGAAGCCCGTGAAGTTCCAGCTGGAGGAC
GACGGCGAGTTCTACATGATCGGCTCCGAGATGACTGTAAAGGAACAACAAGAGTGGAAGATTCCTCCTTGTATTTCTAACTGGAAAAAT
GCAAAGGGTTATACAATTCCATTAGACAAACGTCTGGCTGCTGATGGAAGAGGACTACAGACAGTACACATAAATGAAAATTTCGCCAAA
TTGGCAGAAGCCCTCTACATTGCTGATCGGAAGGCTCGTGAAGCTGTGGAAATGCGTGCCCAAGTAGAGAGAAAAATGGCTCAGAAAGAA
AAGGAAAAACATGAAGAGAAACTTAGAGAAATGGCCCAGAAAGCCAGGGAGAGAAGAGCTGGGATCAAAACTCATGTGGAAAAAGAGGAT
GGGGAGGCACGTGAGAGGGATGAAATCCGGCATGACAGGCGAAAAGAGAGACAGCATGACCGGAATCTTTCCAGGGCAGCTCCTGATAAG
AGGTCGAAACTTCAGAGAAATGAAAATCGGGATATCAGTGAAGTTATTGCTCTCGGTGTTCCTAATCCTCGGACTTCCAATGAAGTTCAG
TATGACCAAAGGCTCTTCAACCAATCCAAGGGTATGGACAGTGGATTTGCAGGTGGAGAAGATGAAATTTATAATGTTTATGATCAAGCC
TGGAGAGGTGGTAAAGATATGGCCCAGAGTATTTATAGGCCCAGTAAAAATCTGGACAAGGACATGTATGGTGATGACCTAGAAGCCAGA
ATAAAGACCAACAGATTTGTTCCCGACAAGGAGTTTTCTGGTTCAGACCGTAGACAGAGAGGCCGAGAAGGACCAGTGCAGTTTGAGGAA
GATCCTTTTGGTTTGGACAAGTTTTTGGAAGAAGCCAAACAGCATGGTGGCTCTAAAAGACCCTCAGATAGCAGCCGCCCCAAGGAACAC
GAGCATGAAGGCAAGAAGAGGAGGAAGGAATAGGCACAGGTCTCTCCAAAGTGAATGAACTCTTACCCATAACCCTAATGATGCAAGTCA
TATGGGGGAACACTTTGTAAATGGTCAGGATAAAAACCAAATCTGGGTGCCAGATCCCAGCACTACTTTTTATTACTGGAGAAATGGGGG
GGATAGAAAATTCTACTTTGAATTATTTAGTTTTTTTTAAAGAGTGGGTTGTGTTTGTGCTTCTCCCACCTTTCAGCATTTATAGAACAT
GCTGCCCCACATACAAAGTCAAGACCACTTACTTTTATGTGACACTAGTAGTTTGGGGTTAATGTTTTGTGTAAGAACAGCTGCATATGA
GTAAAGTTACCCCAACCACAGTGAGGAGGAAGATGTTCACATACTGGAACTGTCCTGCCAAATAAATTTTGCCCCTATTGTGCTCTGTTT

>83932_83932_4_SMARCB1-SNW1_SMARCB1_chr22_24129449_ENST00000344921_SNW1_chr14_78201355_ENST00000261531_length(amino acids)=331AA_BP=29
MMMMALSKTFGQKPVKFQLEDDGEFYMIGSEMTVKEQQEWKIPPCISNWKNAKGYTIPLDKRLAADGRGLQTVHINENFAKLAEALYIAD
RKAREAVEMRAQVERKMAQKEKEKHEEKLREMAQKARERRAGIKTHVEKEDGEARERDEIRHDRRKERQHDRNLSRAAPDKRSKLQRNEN
RDISEVIALGVPNPRTSNEVQYDQRLFNQSKGMDSGFAGGEDEIYNVYDQAWRGGKDMAQSIYRPSKNLDKDMYGDDLEARIKTNRFVPD

--------------------------------------------------------------
>83932_83932_5_SMARCB1-SNW1_SMARCB1_chr22_24129449_ENST00000344921_SNW1_chr14_78201355_ENST00000554775_length(transcript)=1663nt_BP=300nt
AACGCCAGCGCCTGCGCACTGAGGGCGGCCTGGTCGTCGTCTGCGGCGGCGGCGGCGGCTGAGGAGCCCGGCTGAGGCGCCAGTACCCGG
CCCGGTCCGCATTTCGCCTTCCGGCTTCGGTTTCCCTCGGCCCAGCACGCCCCGGCCCCGCCCCAGCCCTCCTGATCCCTCGCAGCCCGG
CTCCGGCCGCCCGCCTCTGCCGCCGCAATGATGATGATGGCGCTGAGCAAGACCTTCGGGCAGAAGCCCGTGAAGTTCCAGCTGGAGGAC
GACGGCGAGTTCTACATGATCGGCTCCGAGATGACTGTAAAGGAACAACAAGAGTGGAAGATTCCTCCTTGTATTTCTAACTGGAAAAAT
GCAAAGGGTTATACAATTCCATTAGACAAACGTCTGGCTGCTGATGGAAGAGGACTACAGACAGTACACATAAATGAAAATTTCGCCAAA
TTGGCAGAAGCCCTCTACATTGCTGATCGGAAGGCTCGTGAAGCTGTGGAAATGCGTGCCCAAGTAGAGAGAAAAATGGCTCAGAAAGAA
AAGGAAAAACATGAAGAGAAACTTAGAGAAATGGCCCAGAAAGCCAGGGAGAGAAGAGCTGGGATCAAAACTCATGTGGAAAAAGAGGAT
GGGGAGGCACGTGAGAGGGATGAAATCCGGCATGACAGGCGAAAAGAGAGACAGCATGACCGGAATCTTTCCAGGGCAGCTCCTGATAAG
AGGTCGAAACTTCAGAGAAATGAAAATCGGGATATCAGTGAAGTTATTGCTCTCGGTGTTCCTAATCCTCGGACTTCCAATGAAGTTCAG
TATGACCAAAGGCTCTTCAACCAATCCAAGGGTATGGACAGTGGATTTGCAGGTGGAGAAGATGAAATTTATAATGTTTATGATCAAGCC
TGGAGAGGTGGTAAAGATATGGCCCAGAGTATTTATAGGCCCAGTAAAAATCTGGACAAGGACATGTATGGTGATGACCTAGAAGCCAGA
ATAAAGACCAACAGATTTGTTCCCGACAAGGAGTTTTCTGGTTCAGACCGTAGACAGAGAGGCCGAGAAGGACCAGTGCAGTTTGAGGAA
GATCCTTTTGGTTTGGACAAGTTTTTGGAAGAAGCCAAACAGCATGGTGGCTCTAAAAGACCCTCAGATAGCAGCCGCCCCAAGGAACAC
GAGCATGAAGGCAAGAAGAGGAGGAAGGAATAGGCACAGGTCTCTCCAAAGTGAATGAACTCTTACCCATAACCCTAATGATGCAAGTCA
TATGGGGGAACACTTTGTAAATGGTCAGGATAAAAACCAAATCTGGGTGCCAGATCCCAGCACTACTTTTTATTACTGGAGAAATGGGGG
GGATAGAAAATTCTACTTTGAATTATTTAGTTTTTTTTAAAGAGTGGGTTGTGTTTGTGCTTCTCCCACCTTTCAGCATTTATAGAACAT
GCTGCCCCACATACAAAGTCAAGACCACTTACTTTTATGTGACACTAGTAGTTTGGGGTTAATGTTTTGTGTAAGAACAGCTGCATATGA
GTAAAGTTACCCCAACCACAGTGAGGAGGAAGATGTTCACATACTGGAACTGTCCTGCCAAATAAATTTTGCCCCTATTGTGCTCTGTTT

>83932_83932_5_SMARCB1-SNW1_SMARCB1_chr22_24129449_ENST00000344921_SNW1_chr14_78201355_ENST00000554775_length(amino acids)=331AA_BP=29
MMMMALSKTFGQKPVKFQLEDDGEFYMIGSEMTVKEQQEWKIPPCISNWKNAKGYTIPLDKRLAADGRGLQTVHINENFAKLAEALYIAD
RKAREAVEMRAQVERKMAQKEKEKHEEKLREMAQKARERRAGIKTHVEKEDGEARERDEIRHDRRKERQHDRNLSRAAPDKRSKLQRNEN
RDISEVIALGVPNPRTSNEVQYDQRLFNQSKGMDSGFAGGEDEIYNVYDQAWRGGKDMAQSIYRPSKNLDKDMYGDDLEARIKTNRFVPD

--------------------------------------------------------------
>83932_83932_6_SMARCB1-SNW1_SMARCB1_chr22_24129449_ENST00000344921_SNW1_chr14_78201355_ENST00000555761_length(transcript)=1418nt_BP=300nt
AACGCCAGCGCCTGCGCACTGAGGGCGGCCTGGTCGTCGTCTGCGGCGGCGGCGGCGGCTGAGGAGCCCGGCTGAGGCGCCAGTACCCGG
CCCGGTCCGCATTTCGCCTTCCGGCTTCGGTTTCCCTCGGCCCAGCACGCCCCGGCCCCGCCCCAGCCCTCCTGATCCCTCGCAGCCCGG
CTCCGGCCGCCCGCCTCTGCCGCCGCAATGATGATGATGGCGCTGAGCAAGACCTTCGGGCAGAAGCCCGTGAAGTTCCAGCTGGAGGAC
GACGGCGAGTTCTACATGATCGGCTCCGAGATGACTGTAAAGGAACAACAAGAGTGGAAGATTCCTCCTTGTATTTCTAACTGGAAAAAT
GCAAAGGGTTATACAATTCCATTAGACAAACGTCTGGCTGCTGATGGAAGAGGACTACAGACAGTACACATAAATGAAAATTTCGCCAAA
TTGGCAGAAGCCCTCTACATTGCTGATCGGAAGGCTCGTGAAGCTGTGGAAATGCGTGCCCAAGTAGAGAGAAAAATGGCTCAGAAAGAA
AAGGAAAAACATGAAGAGAAACTTAGAGAAATGGCCCAGAAAGCCAGGGAGAGAAGAGCTGGGATCAAAACTCATGTGGAAAAAGAGGAT
GGGGAGGCACGTGAGAGGGATGAAATCCGGCATGACAGGCGAAAAGAGAGACAGCATGACCGGAATCTTTCCAGGGCAGCTCCTGATAAG
AGGTCGAAACTTCAGAGAAATGAAAATCGGGATATCAGTGAAGTTATTGCTCTCGGTGTTCCTAATCCTCGGACTTCCAATGAAGTTCAG
TATGACCAAAGGCTCTTCAACCAATCCAAGGGTATGGACAGTGGATTTGCAGGTGGAGAAGATGAAATTTATAATGTTTATGATCAAGCC
TGGAGAGGTGGTAAAGATATGGCCCAGAGTATTTATAGGCCCAGTAAAAATCTGGACAAGGACATGTATGGTGATGACCTAGAAGCCAGA
ATAAAGACCAACAGGTGCCAAGCCATACAACTCAATTTCAGTGTTTACACTGGTGAAAGCAAAGTAGTTCATAGTTTTTTCTCCTTTTCC
TTAGATTTGTTCCCGACAAGGAGTTTTCTGGTTCAGACCGTAGACAGAGAGGCCGAGAAGGACCAGTGCAGTTTGAGGAAGATCCTTTTG
GTTTGGACAAGTTTTTGGAAGAAGCCAAACAGCATGGTGGCTCTAAAAGACCCTCAGATAGCAGCCGCCCCAAGGAACACGAGCATGAAG
GCAAGAAGAGGAGGAAGGAATAGGCACAGGTCTCTCCAAAGTGAATGAACTCTTACCCATAACCCTAATGATGCAAGTCATATGGGGGAA

>83932_83932_6_SMARCB1-SNW1_SMARCB1_chr22_24129449_ENST00000344921_SNW1_chr14_78201355_ENST00000555761_length(amino acids)=366AA_BP=29
MMMMALSKTFGQKPVKFQLEDDGEFYMIGSEMTVKEQQEWKIPPCISNWKNAKGYTIPLDKRLAADGRGLQTVHINENFAKLAEALYIAD
RKAREAVEMRAQVERKMAQKEKEKHEEKLREMAQKARERRAGIKTHVEKEDGEARERDEIRHDRRKERQHDRNLSRAAPDKRSKLQRNEN
RDISEVIALGVPNPRTSNEVQYDQRLFNQSKGMDSGFAGGEDEIYNVYDQAWRGGKDMAQSIYRPSKNLDKDMYGDDLEARIKTNRCQAI
QLNFSVYTGESKVVHSFFSFSLDLFPTRSFLVQTVDREAEKDQCSLRKILLVWTSFWKKPNSMVALKDPQIAAAPRNTSMKARRGGRNRH

--------------------------------------------------------------
>83932_83932_7_SMARCB1-SNW1_SMARCB1_chr22_24129449_ENST00000407082_SNW1_chr14_78201355_ENST00000261531_length(transcript)=1644nt_BP=252nt
GCGGCGGCGGCTGAGGAGCCCGGCTGAGGCGCCAGTACCCGGCCCGGTCCGCATTTCGCCTTCCGGCTTCGGTTTCCCTCGGCCCAGCAC
GCCCCGGCCCCGCCCCAGCCCTCCTGATCCCTCGCAGCCCGGCTCCGGCCGCCCGCCTCTGCCGCCGCAATGATGATGATGGCGCTGAGC
AAGACCTTCGGGCAGAAGCCCGTGAAGTTCCAGCTGGAGGACGACGGCGAGTTCTACATGATCGGCTCCGAGATGACTGTAAAGGAACAA
CAAGAGTGGAAGATTCCTCCTTGTATTTCTAACTGGAAAAATGCAAAGGGTTATACAATTCCATTAGACAAACGTCTGGCTGCTGATGGA
AGAGGACTACAGACAGTACACATAAATGAAAATTTCGCCAAATTGGCAGAAGCCCTCTACATTGCTGATCGGAAGGCTCGTGAAGCTGTG
GAAATGCGTGCCCAAGTAGAGAGAAAAATGGCTCAGAAAGAAAAGGAAAAACATGAAGAGAAACTTAGAGAAATGGCCCAGAAAGCCAGG
GAGAGAAGAGCTGGGATCAAAACTCATGTGGAAAAAGAGGATGGGGAGGCACGTGAGAGGGATGAAATCCGGCATGACAGGCGAAAAGAG
AGACAGCATGACCGGAATCTTTCCAGGGCAGCTCCTGATAAGAGGTCGAAACTTCAGAGAAATGAAAATCGGGATATCAGTGAAGTTATT
GCTCTCGGTGTTCCTAATCCTCGGACTTCCAATGAAGTTCAGTATGACCAAAGGCTCTTCAACCAATCCAAGGGTATGGACAGTGGATTT
GCAGGTGGAGAAGATGAAATTTATAATGTTTATGATCAAGCCTGGAGAGGTGGTAAAGATATGGCCCAGAGTATTTATAGGCCCAGTAAA
AATCTGGACAAGGACATGTATGGTGATGACCTAGAAGCCAGAATAAAGACCAACAGATTTGTTCCCGACAAGGAGTTTTCTGGTTCAGAC
CGTAGACAGAGAGGCCGAGAAGGACCAGTGCAGTTTGAGGAAGATCCTTTTGGTTTGGACAAGTTTTTGGAAGAAGCCAAACAGCATGGT
GGCTCTAAAAGACCCTCAGATAGCAGCCGCCCCAAGGAACACGAGCATGAAGGCAAGAAGAGGAGGAAGGAATAGGCACAGGTCTCTCCA
AAGTGAATGAACTCTTACCCATAACCCTAATGATGCAAGTCATATGGGGGAACACTTTGTAAATGGTCAGGATAAAAACCAAATCTGGGT
GCCAGATCCCAGCACTACTTTTTATTACTGGAGAAATGGGGGGGATAGAAAATTCTACTTTGAATTATTTAGTTTTTTTTAAAGAGTGGG
TTGTGTTTGTGCTTCTCCCACCTTTCAGCATTTATAGAACATGCTGCCCCACATACAAAGTCAAGACCACTTACTTTTATGTGACACTAG
TAGTTTGGGGTTAATGTTTTGTGTAAGAACAGCTGCATATGAGTAAAGTTACCCCAACCACAGTGAGGAGGAAGATGTTCACATACTGGA
ACTGTCCTGCCAAATAAATTTTGCCCCTATTGTGCTCTGTTTTAATTTGGAGTGGGCAAAGTAACCTCTTGCTTGGTGCAACTATTTGTT

>83932_83932_7_SMARCB1-SNW1_SMARCB1_chr22_24129449_ENST00000407082_SNW1_chr14_78201355_ENST00000261531_length(amino acids)=331AA_BP=29
MMMMALSKTFGQKPVKFQLEDDGEFYMIGSEMTVKEQQEWKIPPCISNWKNAKGYTIPLDKRLAADGRGLQTVHINENFAKLAEALYIAD
RKAREAVEMRAQVERKMAQKEKEKHEEKLREMAQKARERRAGIKTHVEKEDGEARERDEIRHDRRKERQHDRNLSRAAPDKRSKLQRNEN
RDISEVIALGVPNPRTSNEVQYDQRLFNQSKGMDSGFAGGEDEIYNVYDQAWRGGKDMAQSIYRPSKNLDKDMYGDDLEARIKTNRFVPD

--------------------------------------------------------------
>83932_83932_8_SMARCB1-SNW1_SMARCB1_chr22_24129449_ENST00000407082_SNW1_chr14_78201355_ENST00000554775_length(transcript)=1615nt_BP=252nt
GCGGCGGCGGCTGAGGAGCCCGGCTGAGGCGCCAGTACCCGGCCCGGTCCGCATTTCGCCTTCCGGCTTCGGTTTCCCTCGGCCCAGCAC
GCCCCGGCCCCGCCCCAGCCCTCCTGATCCCTCGCAGCCCGGCTCCGGCCGCCCGCCTCTGCCGCCGCAATGATGATGATGGCGCTGAGC
AAGACCTTCGGGCAGAAGCCCGTGAAGTTCCAGCTGGAGGACGACGGCGAGTTCTACATGATCGGCTCCGAGATGACTGTAAAGGAACAA
CAAGAGTGGAAGATTCCTCCTTGTATTTCTAACTGGAAAAATGCAAAGGGTTATACAATTCCATTAGACAAACGTCTGGCTGCTGATGGA
AGAGGACTACAGACAGTACACATAAATGAAAATTTCGCCAAATTGGCAGAAGCCCTCTACATTGCTGATCGGAAGGCTCGTGAAGCTGTG
GAAATGCGTGCCCAAGTAGAGAGAAAAATGGCTCAGAAAGAAAAGGAAAAACATGAAGAGAAACTTAGAGAAATGGCCCAGAAAGCCAGG
GAGAGAAGAGCTGGGATCAAAACTCATGTGGAAAAAGAGGATGGGGAGGCACGTGAGAGGGATGAAATCCGGCATGACAGGCGAAAAGAG
AGACAGCATGACCGGAATCTTTCCAGGGCAGCTCCTGATAAGAGGTCGAAACTTCAGAGAAATGAAAATCGGGATATCAGTGAAGTTATT
GCTCTCGGTGTTCCTAATCCTCGGACTTCCAATGAAGTTCAGTATGACCAAAGGCTCTTCAACCAATCCAAGGGTATGGACAGTGGATTT
GCAGGTGGAGAAGATGAAATTTATAATGTTTATGATCAAGCCTGGAGAGGTGGTAAAGATATGGCCCAGAGTATTTATAGGCCCAGTAAA
AATCTGGACAAGGACATGTATGGTGATGACCTAGAAGCCAGAATAAAGACCAACAGATTTGTTCCCGACAAGGAGTTTTCTGGTTCAGAC
CGTAGACAGAGAGGCCGAGAAGGACCAGTGCAGTTTGAGGAAGATCCTTTTGGTTTGGACAAGTTTTTGGAAGAAGCCAAACAGCATGGT
GGCTCTAAAAGACCCTCAGATAGCAGCCGCCCCAAGGAACACGAGCATGAAGGCAAGAAGAGGAGGAAGGAATAGGCACAGGTCTCTCCA
AAGTGAATGAACTCTTACCCATAACCCTAATGATGCAAGTCATATGGGGGAACACTTTGTAAATGGTCAGGATAAAAACCAAATCTGGGT
GCCAGATCCCAGCACTACTTTTTATTACTGGAGAAATGGGGGGGATAGAAAATTCTACTTTGAATTATTTAGTTTTTTTTAAAGAGTGGG
TTGTGTTTGTGCTTCTCCCACCTTTCAGCATTTATAGAACATGCTGCCCCACATACAAAGTCAAGACCACTTACTTTTATGTGACACTAG
TAGTTTGGGGTTAATGTTTTGTGTAAGAACAGCTGCATATGAGTAAAGTTACCCCAACCACAGTGAGGAGGAAGATGTTCACATACTGGA

>83932_83932_8_SMARCB1-SNW1_SMARCB1_chr22_24129449_ENST00000407082_SNW1_chr14_78201355_ENST00000554775_length(amino acids)=331AA_BP=29
MMMMALSKTFGQKPVKFQLEDDGEFYMIGSEMTVKEQQEWKIPPCISNWKNAKGYTIPLDKRLAADGRGLQTVHINENFAKLAEALYIAD
RKAREAVEMRAQVERKMAQKEKEKHEEKLREMAQKARERRAGIKTHVEKEDGEARERDEIRHDRRKERQHDRNLSRAAPDKRSKLQRNEN
RDISEVIALGVPNPRTSNEVQYDQRLFNQSKGMDSGFAGGEDEIYNVYDQAWRGGKDMAQSIYRPSKNLDKDMYGDDLEARIKTNRFVPD

--------------------------------------------------------------
>83932_83932_9_SMARCB1-SNW1_SMARCB1_chr22_24129449_ENST00000407082_SNW1_chr14_78201355_ENST00000555761_length(transcript)=1370nt_BP=252nt
GCGGCGGCGGCTGAGGAGCCCGGCTGAGGCGCCAGTACCCGGCCCGGTCCGCATTTCGCCTTCCGGCTTCGGTTTCCCTCGGCCCAGCAC
GCCCCGGCCCCGCCCCAGCCCTCCTGATCCCTCGCAGCCCGGCTCCGGCCGCCCGCCTCTGCCGCCGCAATGATGATGATGGCGCTGAGC
AAGACCTTCGGGCAGAAGCCCGTGAAGTTCCAGCTGGAGGACGACGGCGAGTTCTACATGATCGGCTCCGAGATGACTGTAAAGGAACAA
CAAGAGTGGAAGATTCCTCCTTGTATTTCTAACTGGAAAAATGCAAAGGGTTATACAATTCCATTAGACAAACGTCTGGCTGCTGATGGA
AGAGGACTACAGACAGTACACATAAATGAAAATTTCGCCAAATTGGCAGAAGCCCTCTACATTGCTGATCGGAAGGCTCGTGAAGCTGTG
GAAATGCGTGCCCAAGTAGAGAGAAAAATGGCTCAGAAAGAAAAGGAAAAACATGAAGAGAAACTTAGAGAAATGGCCCAGAAAGCCAGG
GAGAGAAGAGCTGGGATCAAAACTCATGTGGAAAAAGAGGATGGGGAGGCACGTGAGAGGGATGAAATCCGGCATGACAGGCGAAAAGAG
AGACAGCATGACCGGAATCTTTCCAGGGCAGCTCCTGATAAGAGGTCGAAACTTCAGAGAAATGAAAATCGGGATATCAGTGAAGTTATT
GCTCTCGGTGTTCCTAATCCTCGGACTTCCAATGAAGTTCAGTATGACCAAAGGCTCTTCAACCAATCCAAGGGTATGGACAGTGGATTT
GCAGGTGGAGAAGATGAAATTTATAATGTTTATGATCAAGCCTGGAGAGGTGGTAAAGATATGGCCCAGAGTATTTATAGGCCCAGTAAA
AATCTGGACAAGGACATGTATGGTGATGACCTAGAAGCCAGAATAAAGACCAACAGGTGCCAAGCCATACAACTCAATTTCAGTGTTTAC
ACTGGTGAAAGCAAAGTAGTTCATAGTTTTTTCTCCTTTTCCTTAGATTTGTTCCCGACAAGGAGTTTTCTGGTTCAGACCGTAGACAGA
GAGGCCGAGAAGGACCAGTGCAGTTTGAGGAAGATCCTTTTGGTTTGGACAAGTTTTTGGAAGAAGCCAAACAGCATGGTGGCTCTAAAA
GACCCTCAGATAGCAGCCGCCCCAAGGAACACGAGCATGAAGGCAAGAAGAGGAGGAAGGAATAGGCACAGGTCTCTCCAAAGTGAATGA
ACTCTTACCCATAACCCTAATGATGCAAGTCATATGGGGGAACACTTTGTAAATGGTCAGGATAAAAACCAAATCTGGGTGCCAGATCCC

>83932_83932_9_SMARCB1-SNW1_SMARCB1_chr22_24129449_ENST00000407082_SNW1_chr14_78201355_ENST00000555761_length(amino acids)=366AA_BP=29
MMMMALSKTFGQKPVKFQLEDDGEFYMIGSEMTVKEQQEWKIPPCISNWKNAKGYTIPLDKRLAADGRGLQTVHINENFAKLAEALYIAD
RKAREAVEMRAQVERKMAQKEKEKHEEKLREMAQKARERRAGIKTHVEKEDGEARERDEIRHDRRKERQHDRNLSRAAPDKRSKLQRNEN
RDISEVIALGVPNPRTSNEVQYDQRLFNQSKGMDSGFAGGEDEIYNVYDQAWRGGKDMAQSIYRPSKNLDKDMYGDDLEARIKTNRCQAI
QLNFSVYTGESKVVHSFFSFSLDLFPTRSFLVQTVDREAEKDQCSLRKILLVWTSFWKKPNSMVALKDPQIAAAPRNTSMKARRGGRNRH

--------------------------------------------------------------
>83932_83932_10_SMARCB1-SNW1_SMARCB1_chr22_24129449_ENST00000407422_SNW1_chr14_78201355_ENST00000261531_length(transcript)=1661nt_BP=269nt
GGTCGTCGTCTGCGGCGGCGGCGGCGGCTGAGGAGCCCGGCTGAGGCGCCAGTACCCGGCCCGGTCCGCATTTCGCCTTCCGGCTTCGGT
TTCCCTCGGCCCAGCACGCCCCGGCCCCGCCCCAGCCCTCCTGATCCCTCGCAGCCCGGCTCCGGCCGCCCGCCTCTGCCGCCGCAATGA
TGATGATGGCGCTGAGCAAGACCTTCGGGCAGAAGCCCGTGAAGTTCCAGCTGGAGGACGACGGCGAGTTCTACATGATCGGCTCCGAGA
TGACTGTAAAGGAACAACAAGAGTGGAAGATTCCTCCTTGTATTTCTAACTGGAAAAATGCAAAGGGTTATACAATTCCATTAGACAAAC
GTCTGGCTGCTGATGGAAGAGGACTACAGACAGTACACATAAATGAAAATTTCGCCAAATTGGCAGAAGCCCTCTACATTGCTGATCGGA
AGGCTCGTGAAGCTGTGGAAATGCGTGCCCAAGTAGAGAGAAAAATGGCTCAGAAAGAAAAGGAAAAACATGAAGAGAAACTTAGAGAAA
TGGCCCAGAAAGCCAGGGAGAGAAGAGCTGGGATCAAAACTCATGTGGAAAAAGAGGATGGGGAGGCACGTGAGAGGGATGAAATCCGGC
ATGACAGGCGAAAAGAGAGACAGCATGACCGGAATCTTTCCAGGGCAGCTCCTGATAAGAGGTCGAAACTTCAGAGAAATGAAAATCGGG
ATATCAGTGAAGTTATTGCTCTCGGTGTTCCTAATCCTCGGACTTCCAATGAAGTTCAGTATGACCAAAGGCTCTTCAACCAATCCAAGG
GTATGGACAGTGGATTTGCAGGTGGAGAAGATGAAATTTATAATGTTTATGATCAAGCCTGGAGAGGTGGTAAAGATATGGCCCAGAGTA
TTTATAGGCCCAGTAAAAATCTGGACAAGGACATGTATGGTGATGACCTAGAAGCCAGAATAAAGACCAACAGATTTGTTCCCGACAAGG
AGTTTTCTGGTTCAGACCGTAGACAGAGAGGCCGAGAAGGACCAGTGCAGTTTGAGGAAGATCCTTTTGGTTTGGACAAGTTTTTGGAAG
AAGCCAAACAGCATGGTGGCTCTAAAAGACCCTCAGATAGCAGCCGCCCCAAGGAACACGAGCATGAAGGCAAGAAGAGGAGGAAGGAAT
AGGCACAGGTCTCTCCAAAGTGAATGAACTCTTACCCATAACCCTAATGATGCAAGTCATATGGGGGAACACTTTGTAAATGGTCAGGAT
AAAAACCAAATCTGGGTGCCAGATCCCAGCACTACTTTTTATTACTGGAGAAATGGGGGGGATAGAAAATTCTACTTTGAATTATTTAGT
TTTTTTTAAAGAGTGGGTTGTGTTTGTGCTTCTCCCACCTTTCAGCATTTATAGAACATGCTGCCCCACATACAAAGTCAAGACCACTTA
CTTTTATGTGACACTAGTAGTTTGGGGTTAATGTTTTGTGTAAGAACAGCTGCATATGAGTAAAGTTACCCCAACCACAGTGAGGAGGAA
GATGTTCACATACTGGAACTGTCCTGCCAAATAAATTTTGCCCCTATTGTGCTCTGTTTTAATTTGGAGTGGGCAAAGTAACCTCTTGCT

>83932_83932_10_SMARCB1-SNW1_SMARCB1_chr22_24129449_ENST00000407422_SNW1_chr14_78201355_ENST00000261531_length(amino acids)=331AA_BP=29
MMMMALSKTFGQKPVKFQLEDDGEFYMIGSEMTVKEQQEWKIPPCISNWKNAKGYTIPLDKRLAADGRGLQTVHINENFAKLAEALYIAD
RKAREAVEMRAQVERKMAQKEKEKHEEKLREMAQKARERRAGIKTHVEKEDGEARERDEIRHDRRKERQHDRNLSRAAPDKRSKLQRNEN
RDISEVIALGVPNPRTSNEVQYDQRLFNQSKGMDSGFAGGEDEIYNVYDQAWRGGKDMAQSIYRPSKNLDKDMYGDDLEARIKTNRFVPD

--------------------------------------------------------------
>83932_83932_11_SMARCB1-SNW1_SMARCB1_chr22_24129449_ENST00000407422_SNW1_chr14_78201355_ENST00000554775_length(transcript)=1632nt_BP=269nt
GGTCGTCGTCTGCGGCGGCGGCGGCGGCTGAGGAGCCCGGCTGAGGCGCCAGTACCCGGCCCGGTCCGCATTTCGCCTTCCGGCTTCGGT
TTCCCTCGGCCCAGCACGCCCCGGCCCCGCCCCAGCCCTCCTGATCCCTCGCAGCCCGGCTCCGGCCGCCCGCCTCTGCCGCCGCAATGA
TGATGATGGCGCTGAGCAAGACCTTCGGGCAGAAGCCCGTGAAGTTCCAGCTGGAGGACGACGGCGAGTTCTACATGATCGGCTCCGAGA
TGACTGTAAAGGAACAACAAGAGTGGAAGATTCCTCCTTGTATTTCTAACTGGAAAAATGCAAAGGGTTATACAATTCCATTAGACAAAC
GTCTGGCTGCTGATGGAAGAGGACTACAGACAGTACACATAAATGAAAATTTCGCCAAATTGGCAGAAGCCCTCTACATTGCTGATCGGA
AGGCTCGTGAAGCTGTGGAAATGCGTGCCCAAGTAGAGAGAAAAATGGCTCAGAAAGAAAAGGAAAAACATGAAGAGAAACTTAGAGAAA
TGGCCCAGAAAGCCAGGGAGAGAAGAGCTGGGATCAAAACTCATGTGGAAAAAGAGGATGGGGAGGCACGTGAGAGGGATGAAATCCGGC
ATGACAGGCGAAAAGAGAGACAGCATGACCGGAATCTTTCCAGGGCAGCTCCTGATAAGAGGTCGAAACTTCAGAGAAATGAAAATCGGG
ATATCAGTGAAGTTATTGCTCTCGGTGTTCCTAATCCTCGGACTTCCAATGAAGTTCAGTATGACCAAAGGCTCTTCAACCAATCCAAGG
GTATGGACAGTGGATTTGCAGGTGGAGAAGATGAAATTTATAATGTTTATGATCAAGCCTGGAGAGGTGGTAAAGATATGGCCCAGAGTA
TTTATAGGCCCAGTAAAAATCTGGACAAGGACATGTATGGTGATGACCTAGAAGCCAGAATAAAGACCAACAGATTTGTTCCCGACAAGG
AGTTTTCTGGTTCAGACCGTAGACAGAGAGGCCGAGAAGGACCAGTGCAGTTTGAGGAAGATCCTTTTGGTTTGGACAAGTTTTTGGAAG
AAGCCAAACAGCATGGTGGCTCTAAAAGACCCTCAGATAGCAGCCGCCCCAAGGAACACGAGCATGAAGGCAAGAAGAGGAGGAAGGAAT
AGGCACAGGTCTCTCCAAAGTGAATGAACTCTTACCCATAACCCTAATGATGCAAGTCATATGGGGGAACACTTTGTAAATGGTCAGGAT
AAAAACCAAATCTGGGTGCCAGATCCCAGCACTACTTTTTATTACTGGAGAAATGGGGGGGATAGAAAATTCTACTTTGAATTATTTAGT
TTTTTTTAAAGAGTGGGTTGTGTTTGTGCTTCTCCCACCTTTCAGCATTTATAGAACATGCTGCCCCACATACAAAGTCAAGACCACTTA
CTTTTATGTGACACTAGTAGTTTGGGGTTAATGTTTTGTGTAAGAACAGCTGCATATGAGTAAAGTTACCCCAACCACAGTGAGGAGGAA
GATGTTCACATACTGGAACTGTCCTGCCAAATAAATTTTGCCCCTATTGTGCTCTGTTTTAATTTGGAGTGGGCAAAGTAACCTCTTGCT

>83932_83932_11_SMARCB1-SNW1_SMARCB1_chr22_24129449_ENST00000407422_SNW1_chr14_78201355_ENST00000554775_length(amino acids)=331AA_BP=29
MMMMALSKTFGQKPVKFQLEDDGEFYMIGSEMTVKEQQEWKIPPCISNWKNAKGYTIPLDKRLAADGRGLQTVHINENFAKLAEALYIAD
RKAREAVEMRAQVERKMAQKEKEKHEEKLREMAQKARERRAGIKTHVEKEDGEARERDEIRHDRRKERQHDRNLSRAAPDKRSKLQRNEN
RDISEVIALGVPNPRTSNEVQYDQRLFNQSKGMDSGFAGGEDEIYNVYDQAWRGGKDMAQSIYRPSKNLDKDMYGDDLEARIKTNRFVPD

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>83932_83932_12_SMARCB1-SNW1_SMARCB1_chr22_24129449_ENST00000407422_SNW1_chr14_78201355_ENST00000555761_length(transcript)=1387nt_BP=269nt
GGTCGTCGTCTGCGGCGGCGGCGGCGGCTGAGGAGCCCGGCTGAGGCGCCAGTACCCGGCCCGGTCCGCATTTCGCCTTCCGGCTTCGGT
TTCCCTCGGCCCAGCACGCCCCGGCCCCGCCCCAGCCCTCCTGATCCCTCGCAGCCCGGCTCCGGCCGCCCGCCTCTGCCGCCGCAATGA
TGATGATGGCGCTGAGCAAGACCTTCGGGCAGAAGCCCGTGAAGTTCCAGCTGGAGGACGACGGCGAGTTCTACATGATCGGCTCCGAGA
TGACTGTAAAGGAACAACAAGAGTGGAAGATTCCTCCTTGTATTTCTAACTGGAAAAATGCAAAGGGTTATACAATTCCATTAGACAAAC
GTCTGGCTGCTGATGGAAGAGGACTACAGACAGTACACATAAATGAAAATTTCGCCAAATTGGCAGAAGCCCTCTACATTGCTGATCGGA
AGGCTCGTGAAGCTGTGGAAATGCGTGCCCAAGTAGAGAGAAAAATGGCTCAGAAAGAAAAGGAAAAACATGAAGAGAAACTTAGAGAAA
TGGCCCAGAAAGCCAGGGAGAGAAGAGCTGGGATCAAAACTCATGTGGAAAAAGAGGATGGGGAGGCACGTGAGAGGGATGAAATCCGGC
ATGACAGGCGAAAAGAGAGACAGCATGACCGGAATCTTTCCAGGGCAGCTCCTGATAAGAGGTCGAAACTTCAGAGAAATGAAAATCGGG
ATATCAGTGAAGTTATTGCTCTCGGTGTTCCTAATCCTCGGACTTCCAATGAAGTTCAGTATGACCAAAGGCTCTTCAACCAATCCAAGG
GTATGGACAGTGGATTTGCAGGTGGAGAAGATGAAATTTATAATGTTTATGATCAAGCCTGGAGAGGTGGTAAAGATATGGCCCAGAGTA
TTTATAGGCCCAGTAAAAATCTGGACAAGGACATGTATGGTGATGACCTAGAAGCCAGAATAAAGACCAACAGGTGCCAAGCCATACAAC
TCAATTTCAGTGTTTACACTGGTGAAAGCAAAGTAGTTCATAGTTTTTTCTCCTTTTCCTTAGATTTGTTCCCGACAAGGAGTTTTCTGG
TTCAGACCGTAGACAGAGAGGCCGAGAAGGACCAGTGCAGTTTGAGGAAGATCCTTTTGGTTTGGACAAGTTTTTGGAAGAAGCCAAACA
GCATGGTGGCTCTAAAAGACCCTCAGATAGCAGCCGCCCCAAGGAACACGAGCATGAAGGCAAGAAGAGGAGGAAGGAATAGGCACAGGT
CTCTCCAAAGTGAATGAACTCTTACCCATAACCCTAATGATGCAAGTCATATGGGGGAACACTTTGTAAATGGTCAGGATAAAAACCAAA

>83932_83932_12_SMARCB1-SNW1_SMARCB1_chr22_24129449_ENST00000407422_SNW1_chr14_78201355_ENST00000555761_length(amino acids)=366AA_BP=29
MMMMALSKTFGQKPVKFQLEDDGEFYMIGSEMTVKEQQEWKIPPCISNWKNAKGYTIPLDKRLAADGRGLQTVHINENFAKLAEALYIAD
RKAREAVEMRAQVERKMAQKEKEKHEEKLREMAQKARERRAGIKTHVEKEDGEARERDEIRHDRRKERQHDRNLSRAAPDKRSKLQRNEN
RDISEVIALGVPNPRTSNEVQYDQRLFNQSKGMDSGFAGGEDEIYNVYDQAWRGGKDMAQSIYRPSKNLDKDMYGDDLEARIKTNRCQAI
QLNFSVYTGESKVVHSFFSFSLDLFPTRSFLVQTVDREAEKDQCSLRKILLVWTSFWKKPNSMVALKDPQIAAAPRNTSMKARRGGRNRH

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Fusion Gene PPI Analysis for SMARCB1-SNW1


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with
HgeneSMARCB1chr22:24129449chr14:78201355ENST00000263121+19304_31831.0386.0PPP1R15A
HgeneSMARCB1chr22:24129449chr14:78201355ENST00000407422+19304_31831.0377.0PPP1R15A
TgeneSNW1chr22:24129449chr14:78201355ENST0000026153161459_79236.0537.0PPIL1


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for SMARCB1-SNW1


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for SMARCB1-SNW1


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource