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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:ATXN2-BRAP (FusionGDB2 ID:8416)

Fusion Gene Summary for ATXN2-BRAP

check button Fusion gene summary
Fusion gene informationFusion gene name: ATXN2-BRAP
Fusion gene ID: 8416
HgeneTgene
Gene symbol

ATXN2

BRAP

Gene ID

6311

221477

Gene nameataxin 2chromosome 6 open reading frame 89
SynonymsATX2|SCA2|TNRC13BRAP|PS1TP5TP1
Cytomap

12q24.12

6p21.2

Type of geneprotein-codingprotein-coding
Descriptionataxin-2spinocerebellar ataxia type 2 proteintrinucleotide repeat-containing gene 13 proteinbombesin receptor-activated protein C6orf89amfion
Modification date2020031320200313
UniProtAcc

Q99700

Q7Z569

Ensembl transtripts involved in fusion geneENST00000542287, ENST00000550104, 
ENST00000377617, ENST00000389153, 
ENST00000535949, ENST00000608853, 
ENST00000549455, 		ENST00000327551, 
ENST00000419234, ENST00000539060, 
Fusion gene scores* DoF score22 X 21 X 8=36963 X 3 X 3=27
# samples 253
** MAII scorelog2(25/3696*10)=-3.88596475675397
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(3/27*10)=0.15200309344505
effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs).
DoF>8 and MAII>0
Context

PubMed: ATXN2 [Title/Abstract] AND BRAP [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointATXN2(111947353)-BRAP(112087846), # samples:2
BRAP(112110465)-ATXN2(111902519), # samples:1
BRAP(112120950)-ATXN2(111895163), # samples:1
BRAP(112120950)-ATXN2(111902519), # samples:1
BRAP(112096540)-ATXN2(111908546), # samples:1
Anticipated loss of major functional domain due to fusion event.ATXN2-BRAP seems lost the major protein functional domain in Tgene partner, which is a essential gene due to the frame-shifted ORF.
BRAP-ATXN2 seems lost the major protein functional domain in Hgene partner, which is a essential gene due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
TgeneBRAP

GO:0042060

wound healing

21857995

TgeneBRAP

GO:0045787

positive regulation of cell cycle

21857995

TgeneBRAP

GO:0050673

epithelial cell proliferation

21857995

TgeneBRAP

GO:1901727

positive regulation of histone deacetylase activity

23460338


check buttonFusion gene breakpoints across ATXN2 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across BRAP (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4BLCATCGA-G2-AA3D-01AATXN2chr12

111947353

-BRAPchr12

112087846

-
ChimerDB4BLCATCGA-G2-AA3DATXN2chr12

111947353

-BRAPchr12

112087846

-


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Fusion Gene ORF analysis for ATXN2-BRAP

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
Frame-shiftENST00000542287ENST00000327551ATXN2chr12

111947353

-BRAPchr12

112087846

-
Frame-shiftENST00000542287ENST00000419234ATXN2chr12

111947353

-BRAPchr12

112087846

-
Frame-shiftENST00000542287ENST00000539060ATXN2chr12

111947353

-BRAPchr12

112087846

-
Frame-shiftENST00000550104ENST00000327551ATXN2chr12

111947353

-BRAPchr12

112087846

-
Frame-shiftENST00000550104ENST00000419234ATXN2chr12

111947353

-BRAPchr12

112087846

-
Frame-shiftENST00000550104ENST00000539060ATXN2chr12

111947353

-BRAPchr12

112087846

-
In-frameENST00000377617ENST00000327551ATXN2chr12

111947353

-BRAPchr12

112087846

-
In-frameENST00000377617ENST00000419234ATXN2chr12

111947353

-BRAPchr12

112087846

-
In-frameENST00000377617ENST00000539060ATXN2chr12

111947353

-BRAPchr12

112087846

-
In-frameENST00000389153ENST00000327551ATXN2chr12

111947353

-BRAPchr12

112087846

-
In-frameENST00000389153ENST00000419234ATXN2chr12

111947353

-BRAPchr12

112087846

-
In-frameENST00000389153ENST00000539060ATXN2chr12

111947353

-BRAPchr12

112087846

-
In-frameENST00000535949ENST00000327551ATXN2chr12

111947353

-BRAPchr12

112087846

-
In-frameENST00000535949ENST00000419234ATXN2chr12

111947353

-BRAPchr12

112087846

-
In-frameENST00000535949ENST00000539060ATXN2chr12

111947353

-BRAPchr12

112087846

-
In-frameENST00000608853ENST00000327551ATXN2chr12

111947353

-BRAPchr12

112087846

-
In-frameENST00000608853ENST00000419234ATXN2chr12

111947353

-BRAPchr12

112087846

-
In-frameENST00000608853ENST00000539060ATXN2chr12

111947353

-BRAPchr12

112087846

-
intron-3CDSENST00000549455ENST00000327551ATXN2chr12

111947353

-BRAPchr12

112087846

-
intron-3CDSENST00000549455ENST00000419234ATXN2chr12

111947353

-BRAPchr12

112087846

-
intron-3CDSENST00000549455ENST00000539060ATXN2chr12

111947353

-BRAPchr12

112087846

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000389153ATXN2chr12111947353-ENST00000419234BRAPchr12112087846-42441723312190719
ENST00000389153ATXN2chr12111947353-ENST00000539060BRAPchr12112087846-24511723312190719
ENST00000389153ATXN2chr12111947353-ENST00000327551BRAPchr12112087846-23081723312190719
ENST00000608853ATXN2chr12111947353-ENST00000419234BRAPchr12112087846-477222512532718821
ENST00000608853ATXN2chr12111947353-ENST00000539060BRAPchr12112087846-297922512532718821
ENST00000608853ATXN2chr12111947353-ENST00000327551BRAPchr12112087846-283622512532718821
ENST00000377617ATXN2chr12111947353-ENST00000419234BRAPchr12112087846-509825771623044960
ENST00000377617ATXN2chr12111947353-ENST00000539060BRAPchr12112087846-330525771623044960
ENST00000377617ATXN2chr12111947353-ENST00000327551BRAPchr12112087846-316225771623044960
ENST00000535949ATXN2chr12111947353-ENST00000419234BRAPchr12112087846-419516741262141671
ENST00000535949ATXN2chr12111947353-ENST00000539060BRAPchr12112087846-240216741262141671
ENST00000535949ATXN2chr12111947353-ENST00000327551BRAPchr12112087846-225916741262141671

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000389153ENST00000419234ATXN2chr12111947353-BRAPchr12112087846-0.0003452850.99965477
ENST00000389153ENST00000539060ATXN2chr12111947353-BRAPchr12112087846-0.00141250.9985875
ENST00000389153ENST00000327551ATXN2chr12111947353-BRAPchr12112087846-0.0017753980.99822456
ENST00000608853ENST00000419234ATXN2chr12111947353-BRAPchr12112087846-0.0018980940.9981019
ENST00000608853ENST00000539060ATXN2chr12111947353-BRAPchr12112087846-0.0092484760.9907515
ENST00000608853ENST00000327551ATXN2chr12111947353-BRAPchr12112087846-0.0109794740.9890205
ENST00000377617ENST00000419234ATXN2chr12111947353-BRAPchr12112087846-0.0006625890.9993374
ENST00000377617ENST00000539060ATXN2chr12111947353-BRAPchr12112087846-0.0029194650.9970805
ENST00000377617ENST00000327551ATXN2chr12111947353-BRAPchr12112087846-0.0033936070.99660635
ENST00000535949ENST00000419234ATXN2chr12111947353-BRAPchr12112087846-0.0002182550.9997818
ENST00000535949ENST00000539060ATXN2chr12111947353-BRAPchr12112087846-0.0011947510.9988053
ENST00000535949ENST00000327551ATXN2chr12111947353-BRAPchr12112087846-0.0015449130.99845505

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Fusion Genomic Features for ATXN2-BRAP


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for ATXN2-BRAP


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr12:111947353/chr12:112087846)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
ATXN2

Q99700

BRAP

Q7Z569

FUNCTION: Involved in EGFR trafficking, acting as negative regulator of endocytic EGFR internalization at the plasma membrane. {ECO:0000269|PubMed:18602463}.FUNCTION: Negatively regulates MAP kinase activation by limiting the formation of Raf/MEK complexes probably by inactivation of the KSR1 scaffold protein. Also acts as a Ras responsive E3 ubiquitin ligase that, on activation of Ras, is modified by auto-polyubiquitination resulting in the release of inhibition of Raf/MEK complex formation. May also act as a cytoplasmic retention protein with a role in regulating nuclear transport. {ECO:0000269|PubMed:14724641, ECO:0000303|PubMed:10777491}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneATXN2chr12:111947353chr12:112087846ENST00000377617-1425166_1878051314.0Compositional biasNote=Poly-Gln
HgeneATXN2chr12:111947353chr12:112087846ENST00000377617-1425213_2238051314.0Compositional biasNote=Poly-Ser
HgeneATXN2chr12:111947353chr12:112087846ENST00000377617-142547_1588051314.0Compositional biasNote=Pro-rich
HgeneATXN2chr12:111947353chr12:112087846ENST00000377617-1425551_7348051314.0Compositional biasNote=Pro-rich
HgeneATXN2chr12:111947353chr12:112087846ENST00000377617-142555_648051314.0Compositional biasNote=Poly-Pro
HgeneATXN2chr12:111947353chr12:112087846ENST00000550104-1424166_1878051015.3333333333334Compositional biasNote=Poly-Gln
HgeneATXN2chr12:111947353chr12:112087846ENST00000550104-1424213_2238051015.3333333333334Compositional biasNote=Poly-Ser
HgeneATXN2chr12:111947353chr12:112087846ENST00000550104-142447_1588051015.3333333333334Compositional biasNote=Pro-rich
HgeneATXN2chr12:111947353chr12:112087846ENST00000550104-1424551_7348051015.3333333333334Compositional biasNote=Pro-rich
HgeneATXN2chr12:111947353chr12:112087846ENST00000550104-142455_648051015.3333333333334Compositional biasNote=Poly-Pro

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneATXN2chr12:111947353chr12:112087846ENST00000377617-1425929_10858051314.0Compositional biasNote=Pro-rich
HgeneATXN2chr12:111947353chr12:112087846ENST00000550104-1424929_10858051015.3333333333334Compositional biasNote=Pro-rich
TgeneBRAPchr12:111947353chr12:112087846ENST00000419234912429_537437593.0Coiled coilOntology_term=ECO:0000255
TgeneBRAPchr12:111947353chr12:112087846ENST00000419234912264_304437593.0Zinc fingerRING-type
TgeneBRAPchr12:111947353chr12:112087846ENST00000419234912315_376437593.0Zinc fingerUBP-type


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Fusion Gene Sequence for ATXN2-BRAP


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>8416_8416_1_ATXN2-BRAP_ATXN2_chr12_111947353_ENST00000377617_BRAP_chr12_112087846_ENST00000327551_length(transcript)=3162nt_BP=2577nt
ACCCCCGAGAAAGCAACCCAGCGCGCCGCCCGCTCCTCACGTGTCCCTCCCGGCCCCGGGGCCACCTCACGTTCTGCTTCCGTCTGACCC
CTCCGACTTCCGGTAAAGAGTCCCTATCCGCACCTCCGCTCCCACCCGGCGCCTCGGCGCGCCCGCCCTCCGATGCGCTCAGCGGCCGCA
GCTCCTCGGAGTCCCGCGGTGGCCACCGAGTCTCGCCGCTTCGCCGCAGCCAGGTGGCCCGGGTGGCGCTCGCTCCAGCGGCCGGCGCGG
CGGAGCGGGCGGGGCGGCGGTGGCGCGGCCCCGGGACCGTATCCCTCCGCCGCCCCTCCCCCGCCCGGCCCCGGCCCCCCTCCCTCCCGG
CAGAGCTCGCCTCCCTCCGCCTCAGACTGTTTTGGTAGCAACGGCAACGGCGGCGGCGCGTTTCGGCCCGGCTCCCGGCGGCTCCTTGGT
CTCGGCGGGCCTCCCCGCCCCTTCGTCGTCCTCCTTCTCCCCCTCGCCAGCCCGGGCGCCCCTCCGGCCGCGCCAACCCGCGCCTCCCCG
CTCGGCGCCCGCGCGTCCCCGCCGCGTTCCGGCGTCTCCTTGGCGCGCCCGGCTCCCGGCTGTCCCCGCCCGGCGTGCGAGCCGGTGTAT
GGGCCCCTCACCATGTCGCTGAAGCCCCAGCAGCAGCAGCAGCAGCAGCAGCAGCAGCAGCAGCAGCAACAGCAGCAGCAGCAGCAGCAG
CAGCAGCCGCCGCCCGCGGCTGCCAATGTCCGCAAGCCCGGCGGCAGCGGCCTTCTAGCGTCGCCCGCCGCCGCGCCTTCGCCGTCCTCG
TCCTCGGTCTCCTCGTCCTCGGCCACGGCTCCCTCCTCGGTGGTCGCGGCGACCTCCGGCGGCGGGAGGCCCGGCCTGGGCAGAGGTCGA
AACAGTAACAAAGGACTGCCTCAGTCTACGATTTCTTTTGATGGAATCTATGCAAATATGAGGATGGTTCATATACTTACATCAGTTGTT
GGCTCCAAATGTGAAGTACAAGTGAAAAATGGAGGTATATATGAAGGAGTTTTTAAAACTTACAGTCCGAAGTGTGATTTGGTACTTGAT
GCCGCACATGAGAAAAGTACAGAATCCAGTTCGGGGCCGAAACGTGAAGAAATAATGGAGAGTATTTTGTTCAAATGTTCAGACTTTGTT
GTGGTACAGTTTAAAGATATGGACTCCAGTTATGCAAAAAGAGATGCTTTTACTGACTCTGCTATCAGTGCTAAAGTGAATGGCGAACAC
AAAGAGAAGGACCTGGAGCCCTGGGATGCAGGTGAACTCACAGCCAATGAGGAACTTGAGGCTTTGGAAAATGACGTATCTAATGGATGG
GATCCCAATGATATGTTTCGATATAATGAAGAAAATTATGGTGTAGTGTCTACGTATGATAGCAGTTTATCTTCGTATACAGTGCCCTTA
GAAAGAGATAACTCAGAAGAATTTTTAAAACGGGAAGCAAGGGCAAACCAGTTAGCAGAAGAAATTGAGTCAAGTGCCCAGTACAAAGCT
CGAGTGGCCCTGGAAAATGATGATAGGAGTGAGGAAGAAAAATACACAGCAGTTCAGAGAAATTCCAGTGAACGTGAGGGGCACAGCATA
AACACTAGGGAAAATAAATATATTCCTCCTGGACAAAGAAATAGAGAAGTCATATCCTGGGGAAGTGGGAGACAGAATTCACCGCGTATG
GGCCAGCCTGGATCGGGCTCCATGCCATCAAGATCCACTTCTCACACTTCAGATTTCAACCCGAATTCTGGTTCAGACCAAAGAGTAGTT
AATGGAGGTGTTCCCTGGCCATCGCCTTGCCCATCTCCTTCCTCTCGCCCACCTTCTCGCTACCAGTCAGGTCCCAACTCTCTTCCACCT
CGGGCAGCCACCCCTACACGGCCGCCCTCCAGGCCCCCCTCGCGGCCATCCAGACCCCCGTCTCACCCCTCTGCTCATGGTTCTCCAGCT
CCTGTCTCTACTATGCCTAAACGCATGTCTTCAGAAGGGCCTCCAAGGATGTCCCCAAAGGCCCAGCGACATCCTCGAAATCACAGAGTT
TCTGCTGGGAGGGGTTCCATATCCAGTGGCCTAGAATTTGTATCCCACAACCCACCCAGTGAAGCAGCTACTCCTCCAGTAGCAAGGACC
AGTCCCTCGGGGGGAACGTGGTCATCAGTGGTCAGTGGGGTTCCAAGATTATCCCCTAAAACTCATAGACCCAGGTCTCCCAGACAGAAC
AGTATTGGAAATACCCCCAGTGGGCCAGTTCTTGCTTCTCCCCAAGCTGGTATTATTCCAACTGAAGCTGTTGCCATGCCTATTCCAGCT
GCATCTCCTACGCCTGCTAGTCCTGCATCGAACAGAGCTGTTACCCCTTCTAGTGAGGCTAAAGATTCCAGGCTTCAAGATCAGAGGCAG
AACTCTCCTGCAGGGAATAAAGAAAATATTAAACCCAATGAAACATCACCTAGCTTCTCAAAAGCTGAAAACAAAGGTATATCACCAGTT
GTTTCTGAACATAGAAAACAGATTGATGATTTAAAGAAATTTAAGAATGATTTTAGGATTAACAACATGAAGACCAAGTTTAAAGAAACA
ATTGAGAAGTGTGATAATCTAGAGCACAAACTAAATGATCTCCTAAAAGAAAAGCAGTCTGTGGAAAGAAAGTGCACTCAGCTAAACACA
AAAGTGGCCAAACTCACCAACGAGCTCAAAGAGGAGCAGGAAATGAACAAGTGTTTGCGAGCCAACCAAGTCCTCCTGCAGAACAAGCTA
AAAGAGGAGGAGAGGGTGCTGAAGGAGACCTGTGACCAAAAAGATCTGCAGATCACCGAGATCCAGGAGCAGCTGCGTGACGTCATGTTC
TACCTGGAGACACAGCAGAAGATCAACCATCTGCCTGCCGAGACCCGGCAGGAAATCCAGGAGGGACAGATCAACATCGCCATGGCCTCG
GCCTCGAGCCCTGCCTCTTCGGGGGGCAGTGGGAAGTTGCCCTCCAGGAAGGGCCGCAGCAAGAGGGGCAAGTGACCTTCAGAGCAACAG
ACATCCCTGAGACTGTTCTCCCTGACACTGTGAGAGTGTGCTGGGACCTTCAGCTAAATGTGAGGGTGGGCCCTAATAAGTACAAGTGAG

>8416_8416_1_ATXN2-BRAP_ATXN2_chr12_111947353_ENST00000377617_BRAP_chr12_112087846_ENST00000327551_length(amino acids)=960AA_BP=33
MRSAAAAPRSPAVATESRRFAAARWPGWRSLQRPARRSGRGGGGAAPGPYPSAAPPPPGPGPPPSRQSSPPSASDCFGSNGNGGGAFRPG
SRRLLGLGGPPRPFVVLLLPLASPGAPPAAPTRASPLGARASPPRSGVSLARPAPGCPRPACEPVYGPLTMSLKPQQQQQQQQQQQQQQQ
QQQQQQQQPPPAAANVRKPGGSGLLASPAAAPSPSSSSVSSSSATAPSSVVAATSGGGRPGLGRGRNSNKGLPQSTISFDGIYANMRMVH
ILTSVVGSKCEVQVKNGGIYEGVFKTYSPKCDLVLDAAHEKSTESSSGPKREEIMESILFKCSDFVVVQFKDMDSSYAKRDAFTDSAISA
KVNGEHKEKDLEPWDAGELTANEELEALENDVSNGWDPNDMFRYNEENYGVVSTYDSSLSSYTVPLERDNSEEFLKREARANQLAEEIES
SAQYKARVALENDDRSEEEKYTAVQRNSSEREGHSINTRENKYIPPGQRNREVISWGSGRQNSPRMGQPGSGSMPSRSTSHTSDFNPNSG
SDQRVVNGGVPWPSPCPSPSSRPPSRYQSGPNSLPPRAATPTRPPSRPPSRPSRPPSHPSAHGSPAPVSTMPKRMSSEGPPRMSPKAQRH
PRNHRVSAGRGSISSGLEFVSHNPPSEAATPPVARTSPSGGTWSSVVSGVPRLSPKTHRPRSPRQNSIGNTPSGPVLASPQAGIIPTEAV
AMPIPAASPTPASPASNRAVTPSSEAKDSRLQDQRQNSPAGNKENIKPNETSPSFSKAENKGISPVVSEHRKQIDDLKKFKNDFRINNMK
TKFKETIEKCDNLEHKLNDLLKEKQSVERKCTQLNTKVAKLTNELKEEQEMNKCLRANQVLLQNKLKEEERVLKETCDQKDLQITEIQEQ

--------------------------------------------------------------
>8416_8416_2_ATXN2-BRAP_ATXN2_chr12_111947353_ENST00000377617_BRAP_chr12_112087846_ENST00000419234_length(transcript)=5098nt_BP=2577nt
ACCCCCGAGAAAGCAACCCAGCGCGCCGCCCGCTCCTCACGTGTCCCTCCCGGCCCCGGGGCCACCTCACGTTCTGCTTCCGTCTGACCC
CTCCGACTTCCGGTAAAGAGTCCCTATCCGCACCTCCGCTCCCACCCGGCGCCTCGGCGCGCCCGCCCTCCGATGCGCTCAGCGGCCGCA
GCTCCTCGGAGTCCCGCGGTGGCCACCGAGTCTCGCCGCTTCGCCGCAGCCAGGTGGCCCGGGTGGCGCTCGCTCCAGCGGCCGGCGCGG
CGGAGCGGGCGGGGCGGCGGTGGCGCGGCCCCGGGACCGTATCCCTCCGCCGCCCCTCCCCCGCCCGGCCCCGGCCCCCCTCCCTCCCGG
CAGAGCTCGCCTCCCTCCGCCTCAGACTGTTTTGGTAGCAACGGCAACGGCGGCGGCGCGTTTCGGCCCGGCTCCCGGCGGCTCCTTGGT
CTCGGCGGGCCTCCCCGCCCCTTCGTCGTCCTCCTTCTCCCCCTCGCCAGCCCGGGCGCCCCTCCGGCCGCGCCAACCCGCGCCTCCCCG
CTCGGCGCCCGCGCGTCCCCGCCGCGTTCCGGCGTCTCCTTGGCGCGCCCGGCTCCCGGCTGTCCCCGCCCGGCGTGCGAGCCGGTGTAT
GGGCCCCTCACCATGTCGCTGAAGCCCCAGCAGCAGCAGCAGCAGCAGCAGCAGCAGCAGCAGCAGCAACAGCAGCAGCAGCAGCAGCAG
CAGCAGCCGCCGCCCGCGGCTGCCAATGTCCGCAAGCCCGGCGGCAGCGGCCTTCTAGCGTCGCCCGCCGCCGCGCCTTCGCCGTCCTCG
TCCTCGGTCTCCTCGTCCTCGGCCACGGCTCCCTCCTCGGTGGTCGCGGCGACCTCCGGCGGCGGGAGGCCCGGCCTGGGCAGAGGTCGA
AACAGTAACAAAGGACTGCCTCAGTCTACGATTTCTTTTGATGGAATCTATGCAAATATGAGGATGGTTCATATACTTACATCAGTTGTT
GGCTCCAAATGTGAAGTACAAGTGAAAAATGGAGGTATATATGAAGGAGTTTTTAAAACTTACAGTCCGAAGTGTGATTTGGTACTTGAT
GCCGCACATGAGAAAAGTACAGAATCCAGTTCGGGGCCGAAACGTGAAGAAATAATGGAGAGTATTTTGTTCAAATGTTCAGACTTTGTT
GTGGTACAGTTTAAAGATATGGACTCCAGTTATGCAAAAAGAGATGCTTTTACTGACTCTGCTATCAGTGCTAAAGTGAATGGCGAACAC
AAAGAGAAGGACCTGGAGCCCTGGGATGCAGGTGAACTCACAGCCAATGAGGAACTTGAGGCTTTGGAAAATGACGTATCTAATGGATGG
GATCCCAATGATATGTTTCGATATAATGAAGAAAATTATGGTGTAGTGTCTACGTATGATAGCAGTTTATCTTCGTATACAGTGCCCTTA
GAAAGAGATAACTCAGAAGAATTTTTAAAACGGGAAGCAAGGGCAAACCAGTTAGCAGAAGAAATTGAGTCAAGTGCCCAGTACAAAGCT
CGAGTGGCCCTGGAAAATGATGATAGGAGTGAGGAAGAAAAATACACAGCAGTTCAGAGAAATTCCAGTGAACGTGAGGGGCACAGCATA
AACACTAGGGAAAATAAATATATTCCTCCTGGACAAAGAAATAGAGAAGTCATATCCTGGGGAAGTGGGAGACAGAATTCACCGCGTATG
GGCCAGCCTGGATCGGGCTCCATGCCATCAAGATCCACTTCTCACACTTCAGATTTCAACCCGAATTCTGGTTCAGACCAAAGAGTAGTT
AATGGAGGTGTTCCCTGGCCATCGCCTTGCCCATCTCCTTCCTCTCGCCCACCTTCTCGCTACCAGTCAGGTCCCAACTCTCTTCCACCT
CGGGCAGCCACCCCTACACGGCCGCCCTCCAGGCCCCCCTCGCGGCCATCCAGACCCCCGTCTCACCCCTCTGCTCATGGTTCTCCAGCT
CCTGTCTCTACTATGCCTAAACGCATGTCTTCAGAAGGGCCTCCAAGGATGTCCCCAAAGGCCCAGCGACATCCTCGAAATCACAGAGTT
TCTGCTGGGAGGGGTTCCATATCCAGTGGCCTAGAATTTGTATCCCACAACCCACCCAGTGAAGCAGCTACTCCTCCAGTAGCAAGGACC
AGTCCCTCGGGGGGAACGTGGTCATCAGTGGTCAGTGGGGTTCCAAGATTATCCCCTAAAACTCATAGACCCAGGTCTCCCAGACAGAAC
AGTATTGGAAATACCCCCAGTGGGCCAGTTCTTGCTTCTCCCCAAGCTGGTATTATTCCAACTGAAGCTGTTGCCATGCCTATTCCAGCT
GCATCTCCTACGCCTGCTAGTCCTGCATCGAACAGAGCTGTTACCCCTTCTAGTGAGGCTAAAGATTCCAGGCTTCAAGATCAGAGGCAG
AACTCTCCTGCAGGGAATAAAGAAAATATTAAACCCAATGAAACATCACCTAGCTTCTCAAAAGCTGAAAACAAAGGTATATCACCAGTT
GTTTCTGAACATAGAAAACAGATTGATGATTTAAAGAAATTTAAGAATGATTTTAGGATTAACAACATGAAGACCAAGTTTAAAGAAACA
ATTGAGAAGTGTGATAATCTAGAGCACAAACTAAATGATCTCCTAAAAGAAAAGCAGTCTGTGGAAAGAAAGTGCACTCAGCTAAACACA
AAAGTGGCCAAACTCACCAACGAGCTCAAAGAGGAGCAGGAAATGAACAAGTGTTTGCGAGCCAACCAAGTCCTCCTGCAGAACAAGCTA
AAAGAGGAGGAGAGGGTGCTGAAGGAGACCTGTGACCAAAAAGATCTGCAGATCACCGAGATCCAGGAGCAGCTGCGTGACGTCATGTTC
TACCTGGAGACACAGCAGAAGATCAACCATCTGCCTGCCGAGACCCGGCAGGAAATCCAGGAGGGACAGATCAACATCGCCATGGCCTCG
GCCTCGAGCCCTGCCTCTTCGGGGGGCAGTGGGAAGTTGCCCTCCAGGAAGGGCCGCAGCAAGAGGGGCAAGTGACCTTCAGAGCAACAG
ACATCCCTGAGACTGTTCTCCCTGACACTGTGAGAGTGTGCTGGGACCTTCAGCTAAATGTGAGGGTGGGCCCTAATAAGTACAAGTGAG
GATCAAGCCACAGTTGTTTGGCTCTTTCATTTGCTAGTGTGTGATGTAGTGAATGTAAAGGGTGCTGACTGGAGAGCTGATAGAAAGGCG
CTGCGTTCGAAAAGGTCTTAAGAGTTCACTAACCTCACATTCTAATGACCATTTTGCCTTCCTGCTTGGTAGAAGCCCCAACTCTGCTGT
GCATTTTTCCATTGTATTTATGGAGTTGGCGTATTTGACATTCAGTTCTGGGGTAGGTTTAAGATGTTAAGTTATTTCTTGTAACCTCAA
AGGTAAGGTTATCTAGCACTAAAGCACCAAACCTCTCTGAGGGCATAACAGCTGCTTTAAAGAGAGGTTTCCATTGGCTATTAAGGAGTT
ATGAAAACTCCCTAGCAATAGTGTCATATCATTATCATCTCCCCCTTCCTCTGGGGAGTGGAAGAATTGCTTGAATGTTATCTGAAAAGA
GGCCTGGTAGTAAACCAGGCCCTGGCTCTTTACCAGCAGTCATCTCTTCTTGCTCTGGGGCCAGCCAGGAAAAACAAACAACCCGGGGCA
CATTGGGTAGACTCAGTGTAGGAAAAATGGTGGCAGCTCCACTGTTTATTTTTGGTGACTTCGTACATCATTATGAACCGCAATTAAGGA
GGAGGCTTAATGGCTGTTCCCAAACTCAAATCTCAGAGTGGGTATCCTAGCATCTAGCAAGACTGAGTGGGGAGATTTCTCATCCGTGTG
AAAATGTAGAGTGAGGCCTCTGACTAGCTAATTGTGTATTTTGTTGGGTTTAGTATTTTCTAAATGTTTACAAAATATTGGGCTGCATGT
TCAGGTTGCAGCTAGAGGGAGCTTGGGCAGATTTTCAATTACGCTTTCAAGATATAACCAAAAGCTGTTTCTAAATCCTAAAATTAGAAT
TTCAACAGAGCCCCCTTTAGAACAGTCATATAACGCTTGTGTGGGCCAACAGAGGGGCTGTGTACTCTCTCTGGAACCATAAATGTCAAA
TAATTTATAACCTGCAGTAATTGAGCAAACTTAAAATAAGACCTGTGTTGGAATTTAGTTTCTTGAAGAGGTAGAGGGATAGGTTAGTAA
GATGTATTGTTAAACAACAGGTTTTAGTTTTTGCTTTATAATTAGCCACAGGTTTTCAAATGATCACATTTCAGAATAGGTTTTTAGCCT
GTAATTAGGCCTCATCCCCTTTGACCTAAATGTCTTACATGTTACTTGTTAGCACATCAACTGTATCACTAATCACCATCTGTTTTTGTG
GGATGTGCTGCAGCATTTCCCAAAAAACTTTACGTGTAATGTTGCAAAATGAATGTACTCAGACATTCTTAATTTTTACTTAGGGCAGAC
CAACTCTTTGAGTCTCTCTTGGACTTATATATACAGATATCTTAAGAGTGGGAATGTAAAGCATAACCTAATTCTCTTTCCTATAGAGAT
TCTATTTTATTTAAAATCTATTTTTACACTAGTTAGAATCCTGCTGTTTTGGCCAAGTACTTGTCTTGCATGTCTGACCTTGCAGAAGCT
GGGGTGGATCATAGCATACTAATGAAGAGAATTAGAAGTAGTTTACAAAGCTCGCTCACTCCTCATTTCTCTGTGATCCCTTCTATCCAG
TGGCCCCACCACCACCTGGGAAAACAGATTTTTCAGTACAGGTGGGATAAATGCTCTGAAAGGCTGTGCCCAGAGGAATGAGCAAATAGG
CAAGTGTTTCCAAACTACTTGGAGGTTTACAAAAAATATGTCCCAGAAAAAAAAAAAATCTTACCAAGATACGTAAAGAAAAAAAAATTT
TTTTTTAAACAGTCAAAGAGTCATGTTTGAATTTCACAAAATCACATCAGACAGAAGTTGTTTTCTTCAGGAGGGAAATGAACCACTTAA

>8416_8416_2_ATXN2-BRAP_ATXN2_chr12_111947353_ENST00000377617_BRAP_chr12_112087846_ENST00000419234_length(amino acids)=960AA_BP=33
MRSAAAAPRSPAVATESRRFAAARWPGWRSLQRPARRSGRGGGGAAPGPYPSAAPPPPGPGPPPSRQSSPPSASDCFGSNGNGGGAFRPG
SRRLLGLGGPPRPFVVLLLPLASPGAPPAAPTRASPLGARASPPRSGVSLARPAPGCPRPACEPVYGPLTMSLKPQQQQQQQQQQQQQQQ
QQQQQQQQPPPAAANVRKPGGSGLLASPAAAPSPSSSSVSSSSATAPSSVVAATSGGGRPGLGRGRNSNKGLPQSTISFDGIYANMRMVH
ILTSVVGSKCEVQVKNGGIYEGVFKTYSPKCDLVLDAAHEKSTESSSGPKREEIMESILFKCSDFVVVQFKDMDSSYAKRDAFTDSAISA
KVNGEHKEKDLEPWDAGELTANEELEALENDVSNGWDPNDMFRYNEENYGVVSTYDSSLSSYTVPLERDNSEEFLKREARANQLAEEIES
SAQYKARVALENDDRSEEEKYTAVQRNSSEREGHSINTRENKYIPPGQRNREVISWGSGRQNSPRMGQPGSGSMPSRSTSHTSDFNPNSG
SDQRVVNGGVPWPSPCPSPSSRPPSRYQSGPNSLPPRAATPTRPPSRPPSRPSRPPSHPSAHGSPAPVSTMPKRMSSEGPPRMSPKAQRH
PRNHRVSAGRGSISSGLEFVSHNPPSEAATPPVARTSPSGGTWSSVVSGVPRLSPKTHRPRSPRQNSIGNTPSGPVLASPQAGIIPTEAV
AMPIPAASPTPASPASNRAVTPSSEAKDSRLQDQRQNSPAGNKENIKPNETSPSFSKAENKGISPVVSEHRKQIDDLKKFKNDFRINNMK
TKFKETIEKCDNLEHKLNDLLKEKQSVERKCTQLNTKVAKLTNELKEEQEMNKCLRANQVLLQNKLKEEERVLKETCDQKDLQITEIQEQ

--------------------------------------------------------------
>8416_8416_3_ATXN2-BRAP_ATXN2_chr12_111947353_ENST00000377617_BRAP_chr12_112087846_ENST00000539060_length(transcript)=3305nt_BP=2577nt
ACCCCCGAGAAAGCAACCCAGCGCGCCGCCCGCTCCTCACGTGTCCCTCCCGGCCCCGGGGCCACCTCACGTTCTGCTTCCGTCTGACCC
CTCCGACTTCCGGTAAAGAGTCCCTATCCGCACCTCCGCTCCCACCCGGCGCCTCGGCGCGCCCGCCCTCCGATGCGCTCAGCGGCCGCA
GCTCCTCGGAGTCCCGCGGTGGCCACCGAGTCTCGCCGCTTCGCCGCAGCCAGGTGGCCCGGGTGGCGCTCGCTCCAGCGGCCGGCGCGG
CGGAGCGGGCGGGGCGGCGGTGGCGCGGCCCCGGGACCGTATCCCTCCGCCGCCCCTCCCCCGCCCGGCCCCGGCCCCCCTCCCTCCCGG
CAGAGCTCGCCTCCCTCCGCCTCAGACTGTTTTGGTAGCAACGGCAACGGCGGCGGCGCGTTTCGGCCCGGCTCCCGGCGGCTCCTTGGT
CTCGGCGGGCCTCCCCGCCCCTTCGTCGTCCTCCTTCTCCCCCTCGCCAGCCCGGGCGCCCCTCCGGCCGCGCCAACCCGCGCCTCCCCG
CTCGGCGCCCGCGCGTCCCCGCCGCGTTCCGGCGTCTCCTTGGCGCGCCCGGCTCCCGGCTGTCCCCGCCCGGCGTGCGAGCCGGTGTAT
GGGCCCCTCACCATGTCGCTGAAGCCCCAGCAGCAGCAGCAGCAGCAGCAGCAGCAGCAGCAGCAGCAACAGCAGCAGCAGCAGCAGCAG
CAGCAGCCGCCGCCCGCGGCTGCCAATGTCCGCAAGCCCGGCGGCAGCGGCCTTCTAGCGTCGCCCGCCGCCGCGCCTTCGCCGTCCTCG
TCCTCGGTCTCCTCGTCCTCGGCCACGGCTCCCTCCTCGGTGGTCGCGGCGACCTCCGGCGGCGGGAGGCCCGGCCTGGGCAGAGGTCGA
AACAGTAACAAAGGACTGCCTCAGTCTACGATTTCTTTTGATGGAATCTATGCAAATATGAGGATGGTTCATATACTTACATCAGTTGTT
GGCTCCAAATGTGAAGTACAAGTGAAAAATGGAGGTATATATGAAGGAGTTTTTAAAACTTACAGTCCGAAGTGTGATTTGGTACTTGAT
GCCGCACATGAGAAAAGTACAGAATCCAGTTCGGGGCCGAAACGTGAAGAAATAATGGAGAGTATTTTGTTCAAATGTTCAGACTTTGTT
GTGGTACAGTTTAAAGATATGGACTCCAGTTATGCAAAAAGAGATGCTTTTACTGACTCTGCTATCAGTGCTAAAGTGAATGGCGAACAC
AAAGAGAAGGACCTGGAGCCCTGGGATGCAGGTGAACTCACAGCCAATGAGGAACTTGAGGCTTTGGAAAATGACGTATCTAATGGATGG
GATCCCAATGATATGTTTCGATATAATGAAGAAAATTATGGTGTAGTGTCTACGTATGATAGCAGTTTATCTTCGTATACAGTGCCCTTA
GAAAGAGATAACTCAGAAGAATTTTTAAAACGGGAAGCAAGGGCAAACCAGTTAGCAGAAGAAATTGAGTCAAGTGCCCAGTACAAAGCT
CGAGTGGCCCTGGAAAATGATGATAGGAGTGAGGAAGAAAAATACACAGCAGTTCAGAGAAATTCCAGTGAACGTGAGGGGCACAGCATA
AACACTAGGGAAAATAAATATATTCCTCCTGGACAAAGAAATAGAGAAGTCATATCCTGGGGAAGTGGGAGACAGAATTCACCGCGTATG
GGCCAGCCTGGATCGGGCTCCATGCCATCAAGATCCACTTCTCACACTTCAGATTTCAACCCGAATTCTGGTTCAGACCAAAGAGTAGTT
AATGGAGGTGTTCCCTGGCCATCGCCTTGCCCATCTCCTTCCTCTCGCCCACCTTCTCGCTACCAGTCAGGTCCCAACTCTCTTCCACCT
CGGGCAGCCACCCCTACACGGCCGCCCTCCAGGCCCCCCTCGCGGCCATCCAGACCCCCGTCTCACCCCTCTGCTCATGGTTCTCCAGCT
CCTGTCTCTACTATGCCTAAACGCATGTCTTCAGAAGGGCCTCCAAGGATGTCCCCAAAGGCCCAGCGACATCCTCGAAATCACAGAGTT
TCTGCTGGGAGGGGTTCCATATCCAGTGGCCTAGAATTTGTATCCCACAACCCACCCAGTGAAGCAGCTACTCCTCCAGTAGCAAGGACC
AGTCCCTCGGGGGGAACGTGGTCATCAGTGGTCAGTGGGGTTCCAAGATTATCCCCTAAAACTCATAGACCCAGGTCTCCCAGACAGAAC
AGTATTGGAAATACCCCCAGTGGGCCAGTTCTTGCTTCTCCCCAAGCTGGTATTATTCCAACTGAAGCTGTTGCCATGCCTATTCCAGCT
GCATCTCCTACGCCTGCTAGTCCTGCATCGAACAGAGCTGTTACCCCTTCTAGTGAGGCTAAAGATTCCAGGCTTCAAGATCAGAGGCAG
AACTCTCCTGCAGGGAATAAAGAAAATATTAAACCCAATGAAACATCACCTAGCTTCTCAAAAGCTGAAAACAAAGGTATATCACCAGTT
GTTTCTGAACATAGAAAACAGATTGATGATTTAAAGAAATTTAAGAATGATTTTAGGATTAACAACATGAAGACCAAGTTTAAAGAAACA
ATTGAGAAGTGTGATAATCTAGAGCACAAACTAAATGATCTCCTAAAAGAAAAGCAGTCTGTGGAAAGAAAGTGCACTCAGCTAAACACA
AAAGTGGCCAAACTCACCAACGAGCTCAAAGAGGAGCAGGAAATGAACAAGTGTTTGCGAGCCAACCAAGTCCTCCTGCAGAACAAGCTA
AAAGAGGAGGAGAGGGTGCTGAAGGAGACCTGTGACCAAAAAGATCTGCAGATCACCGAGATCCAGGAGCAGCTGCGTGACGTCATGTTC
TACCTGGAGACACAGCAGAAGATCAACCATCTGCCTGCCGAGACCCGGCAGGAAATCCAGGAGGGACAGATCAACATCGCCATGGCCTCG
GCCTCGAGCCCTGCCTCTTCGGGGGGCAGTGGGAAGTTGCCCTCCAGGAAGGGCCGCAGCAAGAGGGGCAAGTGACCTTCAGAGCAACAG
ACATCCCTGAGACTGTTCTCCCTGACACTGTGAGAGTGTGCTGGGACCTTCAGCTAAATGTGAGGGTGGGCCCTAATAAGTACAAGTGAG
GATCAAGCCACAGTTGTTTGGCTCTTTCATTTGCTAGTGTGTGATGTAGTGAATGTAAAGGGTGCTGACTGGAGAGCTGATAGAAAGGCG

>8416_8416_3_ATXN2-BRAP_ATXN2_chr12_111947353_ENST00000377617_BRAP_chr12_112087846_ENST00000539060_length(amino acids)=960AA_BP=33
MRSAAAAPRSPAVATESRRFAAARWPGWRSLQRPARRSGRGGGGAAPGPYPSAAPPPPGPGPPPSRQSSPPSASDCFGSNGNGGGAFRPG
SRRLLGLGGPPRPFVVLLLPLASPGAPPAAPTRASPLGARASPPRSGVSLARPAPGCPRPACEPVYGPLTMSLKPQQQQQQQQQQQQQQQ
QQQQQQQQPPPAAANVRKPGGSGLLASPAAAPSPSSSSVSSSSATAPSSVVAATSGGGRPGLGRGRNSNKGLPQSTISFDGIYANMRMVH
ILTSVVGSKCEVQVKNGGIYEGVFKTYSPKCDLVLDAAHEKSTESSSGPKREEIMESILFKCSDFVVVQFKDMDSSYAKRDAFTDSAISA
KVNGEHKEKDLEPWDAGELTANEELEALENDVSNGWDPNDMFRYNEENYGVVSTYDSSLSSYTVPLERDNSEEFLKREARANQLAEEIES
SAQYKARVALENDDRSEEEKYTAVQRNSSEREGHSINTRENKYIPPGQRNREVISWGSGRQNSPRMGQPGSGSMPSRSTSHTSDFNPNSG
SDQRVVNGGVPWPSPCPSPSSRPPSRYQSGPNSLPPRAATPTRPPSRPPSRPSRPPSHPSAHGSPAPVSTMPKRMSSEGPPRMSPKAQRH
PRNHRVSAGRGSISSGLEFVSHNPPSEAATPPVARTSPSGGTWSSVVSGVPRLSPKTHRPRSPRQNSIGNTPSGPVLASPQAGIIPTEAV
AMPIPAASPTPASPASNRAVTPSSEAKDSRLQDQRQNSPAGNKENIKPNETSPSFSKAENKGISPVVSEHRKQIDDLKKFKNDFRINNMK
TKFKETIEKCDNLEHKLNDLLKEKQSVERKCTQLNTKVAKLTNELKEEQEMNKCLRANQVLLQNKLKEEERVLKETCDQKDLQITEIQEQ

--------------------------------------------------------------
>8416_8416_4_ATXN2-BRAP_ATXN2_chr12_111947353_ENST00000389153_BRAP_chr12_112087846_ENST00000327551_length(transcript)=2308nt_BP=1723nt
CGCGGCGACCTCCGGCGGCGGGAGGCCCGGCCTGGGCAGAGGTCGAAACAGTAACAAAGGACTGCCTCAGTCTACGATTTCTTTTGATGG
AATCTATGCAAATATGAGGATGGTTCATATACTTACATCAGTTGTTGGCTCCAAATGTGAAGTACAAGTGAAAAATGGAGGTATATATGA
AGGAGTTTTTAAAACTTACAGTCCGAAGTGTGATTTGGTACTTGATGCCGCACATGAGAAAAGTACAGAATCCAGTTCGGGGCCGAAACG
TGAAGAAATAATGGAGAGTATTTTGTTCAAATGTTCAGACTTTGTTGTGGTACAGTTTAAAGATATGGACTCCAGTTATGCAAAAAGAGA
TGCTTTTACTGACTCTGCTATCAGTGCTAAAGTGAATGGCGAACACAAAGAGAAGGACCTGGAGCCCTGGGATGCAGGTGAACTCACAGC
CAATGAGGAACTTGAGGCTTTGGAAAATGACGTATCTAATGGATGGGATCCCAATGATATGTTTCGATATAATGAAGAAAATTATGGTGT
AGTGTCTACGTATGATAGCAGTTTATCTTCGTATACAGTGCCCTTAGAAAGAGATAACTCAGAAGAATTTTTAAAACGGGAAGCAAGGGC
AAACCAGTTAGCAGAAGAAATTGAGTCAAGTGCCCAGTACAAAGCTCGAGTGGCCCTGGAAAATGATGATAGGAGTGAGGAAGAAAAATA
CACAGCAGTTCAGAGAAATTCCAGTGAACGTGAGGGGCACAGCATAAACACTAGGGAAAATAAATATATTCCTCCTGGACAAAGAAATAG
AGAAGTCATATCCTGGGGAAGTGGGAGACAGAATTCACCGCGTATGGGCCAGCCTGGATCGGGCTCCATGCCATCAAGATCCACTTCTCA
CACTTCAGATTTCAACCCGAATTCTGGTTCAGACCAAAGAGTAGTTAATGGAGGTGTTCCCTGGCCATCGCCTTGCCCATCTCCTTCCTC
TCGCCCACCTTCTCGCTACCAGTCAGGTCCCAACTCTCTTCCACCTCGGGCAGCCACCCCTACACGGCCGCCCTCCAGGCCCCCCTCGCG
GCCATCCAGACCCCCGTCTCACCCCTCTGCTCATGGTTCTCCAGCTCCTGTCTCTACTATGCCTAAACGCATGTCTTCAGAAGGGCCTCC
AAGGATGTCCCCAAAGGCCCAGCGACATCCTCGAAATCACAGAGTTTCTGCTGGGAGGGGTTCCATATCCAGTGGCCTAGAATTTGTATC
CCACAACCCACCCAGTGAAGCAGCTACTCCTCCAGTAGCAAGGACCAGTCCCTCGGGGGGAACGTGGTCATCAGTGGTCAGTGGGGTTCC
AAGATTATCCCCTAAAACTCATAGACCCAGGTCTCCCAGACAGAACAGTATTGGAAATACCCCCAGTGGGCCAGTTCTTGCTTCTCCCCA
AGCTGGTATTATTCCAACTGAAGCTGTTGCCATGCCTATTCCAGCTGCATCTCCTACGCCTGCTAGTCCTGCATCGAACAGAGCTGTTAC
CCCTTCTAGTGAGGCTAAAGATTCCAGGCTTCAAGATCAGAGGCAGAACTCTCCTGCAGGGAATAAAGAAAATATTAAACCCAATGAAAC
ATCACCTAGCTTCTCAAAAGCTGAAAACAAAGGTATATCACCAGTTGTTTCTGAACATAGAAAACAGATTGATGATTTAAAGAAATTTAA
GAATGATTTTAGGATTAACAACATGAAGACCAAGTTTAAAGAAACAATTGAGAAGTGTGATAATCTAGAGCACAAACTAAATGATCTCCT
AAAAGAAAAGCAGTCTGTGGAAAGAAAGTGCACTCAGCTAAACACAAAAGTGGCCAAACTCACCAACGAGCTCAAAGAGGAGCAGGAAAT
GAACAAGTGTTTGCGAGCCAACCAAGTCCTCCTGCAGAACAAGCTAAAAGAGGAGGAGAGGGTGCTGAAGGAGACCTGTGACCAAAAAGA
TCTGCAGATCACCGAGATCCAGGAGCAGCTGCGTGACGTCATGTTCTACCTGGAGACACAGCAGAAGATCAACCATCTGCCTGCCGAGAC
CCGGCAGGAAATCCAGGAGGGACAGATCAACATCGCCATGGCCTCGGCCTCGAGCCCTGCCTCTTCGGGGGGCAGTGGGAAGTTGCCCTC
CAGGAAGGGCCGCAGCAAGAGGGGCAAGTGACCTTCAGAGCAACAGACATCCCTGAGACTGTTCTCCCTGACACTGTGAGAGTGTGCTGG

>8416_8416_4_ATXN2-BRAP_ATXN2_chr12_111947353_ENST00000389153_BRAP_chr12_112087846_ENST00000327551_length(amino acids)=719AA_BP=562
MGRGRNSNKGLPQSTISFDGIYANMRMVHILTSVVGSKCEVQVKNGGIYEGVFKTYSPKCDLVLDAAHEKSTESSSGPKREEIMESILFK
CSDFVVVQFKDMDSSYAKRDAFTDSAISAKVNGEHKEKDLEPWDAGELTANEELEALENDVSNGWDPNDMFRYNEENYGVVSTYDSSLSS
YTVPLERDNSEEFLKREARANQLAEEIESSAQYKARVALENDDRSEEEKYTAVQRNSSEREGHSINTRENKYIPPGQRNREVISWGSGRQ
NSPRMGQPGSGSMPSRSTSHTSDFNPNSGSDQRVVNGGVPWPSPCPSPSSRPPSRYQSGPNSLPPRAATPTRPPSRPPSRPSRPPSHPSA
HGSPAPVSTMPKRMSSEGPPRMSPKAQRHPRNHRVSAGRGSISSGLEFVSHNPPSEAATPPVARTSPSGGTWSSVVSGVPRLSPKTHRPR
SPRQNSIGNTPSGPVLASPQAGIIPTEAVAMPIPAASPTPASPASNRAVTPSSEAKDSRLQDQRQNSPAGNKENIKPNETSPSFSKAENK
GISPVVSEHRKQIDDLKKFKNDFRINNMKTKFKETIEKCDNLEHKLNDLLKEKQSVERKCTQLNTKVAKLTNELKEEQEMNKCLRANQVL

--------------------------------------------------------------
>8416_8416_5_ATXN2-BRAP_ATXN2_chr12_111947353_ENST00000389153_BRAP_chr12_112087846_ENST00000419234_length(transcript)=4244nt_BP=1723nt
CGCGGCGACCTCCGGCGGCGGGAGGCCCGGCCTGGGCAGAGGTCGAAACAGTAACAAAGGACTGCCTCAGTCTACGATTTCTTTTGATGG
AATCTATGCAAATATGAGGATGGTTCATATACTTACATCAGTTGTTGGCTCCAAATGTGAAGTACAAGTGAAAAATGGAGGTATATATGA
AGGAGTTTTTAAAACTTACAGTCCGAAGTGTGATTTGGTACTTGATGCCGCACATGAGAAAAGTACAGAATCCAGTTCGGGGCCGAAACG
TGAAGAAATAATGGAGAGTATTTTGTTCAAATGTTCAGACTTTGTTGTGGTACAGTTTAAAGATATGGACTCCAGTTATGCAAAAAGAGA
TGCTTTTACTGACTCTGCTATCAGTGCTAAAGTGAATGGCGAACACAAAGAGAAGGACCTGGAGCCCTGGGATGCAGGTGAACTCACAGC
CAATGAGGAACTTGAGGCTTTGGAAAATGACGTATCTAATGGATGGGATCCCAATGATATGTTTCGATATAATGAAGAAAATTATGGTGT
AGTGTCTACGTATGATAGCAGTTTATCTTCGTATACAGTGCCCTTAGAAAGAGATAACTCAGAAGAATTTTTAAAACGGGAAGCAAGGGC
AAACCAGTTAGCAGAAGAAATTGAGTCAAGTGCCCAGTACAAAGCTCGAGTGGCCCTGGAAAATGATGATAGGAGTGAGGAAGAAAAATA
CACAGCAGTTCAGAGAAATTCCAGTGAACGTGAGGGGCACAGCATAAACACTAGGGAAAATAAATATATTCCTCCTGGACAAAGAAATAG
AGAAGTCATATCCTGGGGAAGTGGGAGACAGAATTCACCGCGTATGGGCCAGCCTGGATCGGGCTCCATGCCATCAAGATCCACTTCTCA
CACTTCAGATTTCAACCCGAATTCTGGTTCAGACCAAAGAGTAGTTAATGGAGGTGTTCCCTGGCCATCGCCTTGCCCATCTCCTTCCTC
TCGCCCACCTTCTCGCTACCAGTCAGGTCCCAACTCTCTTCCACCTCGGGCAGCCACCCCTACACGGCCGCCCTCCAGGCCCCCCTCGCG
GCCATCCAGACCCCCGTCTCACCCCTCTGCTCATGGTTCTCCAGCTCCTGTCTCTACTATGCCTAAACGCATGTCTTCAGAAGGGCCTCC
AAGGATGTCCCCAAAGGCCCAGCGACATCCTCGAAATCACAGAGTTTCTGCTGGGAGGGGTTCCATATCCAGTGGCCTAGAATTTGTATC
CCACAACCCACCCAGTGAAGCAGCTACTCCTCCAGTAGCAAGGACCAGTCCCTCGGGGGGAACGTGGTCATCAGTGGTCAGTGGGGTTCC
AAGATTATCCCCTAAAACTCATAGACCCAGGTCTCCCAGACAGAACAGTATTGGAAATACCCCCAGTGGGCCAGTTCTTGCTTCTCCCCA
AGCTGGTATTATTCCAACTGAAGCTGTTGCCATGCCTATTCCAGCTGCATCTCCTACGCCTGCTAGTCCTGCATCGAACAGAGCTGTTAC
CCCTTCTAGTGAGGCTAAAGATTCCAGGCTTCAAGATCAGAGGCAGAACTCTCCTGCAGGGAATAAAGAAAATATTAAACCCAATGAAAC
ATCACCTAGCTTCTCAAAAGCTGAAAACAAAGGTATATCACCAGTTGTTTCTGAACATAGAAAACAGATTGATGATTTAAAGAAATTTAA
GAATGATTTTAGGATTAACAACATGAAGACCAAGTTTAAAGAAACAATTGAGAAGTGTGATAATCTAGAGCACAAACTAAATGATCTCCT
AAAAGAAAAGCAGTCTGTGGAAAGAAAGTGCACTCAGCTAAACACAAAAGTGGCCAAACTCACCAACGAGCTCAAAGAGGAGCAGGAAAT
GAACAAGTGTTTGCGAGCCAACCAAGTCCTCCTGCAGAACAAGCTAAAAGAGGAGGAGAGGGTGCTGAAGGAGACCTGTGACCAAAAAGA
TCTGCAGATCACCGAGATCCAGGAGCAGCTGCGTGACGTCATGTTCTACCTGGAGACACAGCAGAAGATCAACCATCTGCCTGCCGAGAC
CCGGCAGGAAATCCAGGAGGGACAGATCAACATCGCCATGGCCTCGGCCTCGAGCCCTGCCTCTTCGGGGGGCAGTGGGAAGTTGCCCTC
CAGGAAGGGCCGCAGCAAGAGGGGCAAGTGACCTTCAGAGCAACAGACATCCCTGAGACTGTTCTCCCTGACACTGTGAGAGTGTGCTGG
GACCTTCAGCTAAATGTGAGGGTGGGCCCTAATAAGTACAAGTGAGGATCAAGCCACAGTTGTTTGGCTCTTTCATTTGCTAGTGTGTGA
TGTAGTGAATGTAAAGGGTGCTGACTGGAGAGCTGATAGAAAGGCGCTGCGTTCGAAAAGGTCTTAAGAGTTCACTAACCTCACATTCTA
ATGACCATTTTGCCTTCCTGCTTGGTAGAAGCCCCAACTCTGCTGTGCATTTTTCCATTGTATTTATGGAGTTGGCGTATTTGACATTCA
GTTCTGGGGTAGGTTTAAGATGTTAAGTTATTTCTTGTAACCTCAAAGGTAAGGTTATCTAGCACTAAAGCACCAAACCTCTCTGAGGGC
ATAACAGCTGCTTTAAAGAGAGGTTTCCATTGGCTATTAAGGAGTTATGAAAACTCCCTAGCAATAGTGTCATATCATTATCATCTCCCC
CTTCCTCTGGGGAGTGGAAGAATTGCTTGAATGTTATCTGAAAAGAGGCCTGGTAGTAAACCAGGCCCTGGCTCTTTACCAGCAGTCATC
TCTTCTTGCTCTGGGGCCAGCCAGGAAAAACAAACAACCCGGGGCACATTGGGTAGACTCAGTGTAGGAAAAATGGTGGCAGCTCCACTG
TTTATTTTTGGTGACTTCGTACATCATTATGAACCGCAATTAAGGAGGAGGCTTAATGGCTGTTCCCAAACTCAAATCTCAGAGTGGGTA
TCCTAGCATCTAGCAAGACTGAGTGGGGAGATTTCTCATCCGTGTGAAAATGTAGAGTGAGGCCTCTGACTAGCTAATTGTGTATTTTGT
TGGGTTTAGTATTTTCTAAATGTTTACAAAATATTGGGCTGCATGTTCAGGTTGCAGCTAGAGGGAGCTTGGGCAGATTTTCAATTACGC
TTTCAAGATATAACCAAAAGCTGTTTCTAAATCCTAAAATTAGAATTTCAACAGAGCCCCCTTTAGAACAGTCATATAACGCTTGTGTGG
GCCAACAGAGGGGCTGTGTACTCTCTCTGGAACCATAAATGTCAAATAATTTATAACCTGCAGTAATTGAGCAAACTTAAAATAAGACCT
GTGTTGGAATTTAGTTTCTTGAAGAGGTAGAGGGATAGGTTAGTAAGATGTATTGTTAAACAACAGGTTTTAGTTTTTGCTTTATAATTA
GCCACAGGTTTTCAAATGATCACATTTCAGAATAGGTTTTTAGCCTGTAATTAGGCCTCATCCCCTTTGACCTAAATGTCTTACATGTTA
CTTGTTAGCACATCAACTGTATCACTAATCACCATCTGTTTTTGTGGGATGTGCTGCAGCATTTCCCAAAAAACTTTACGTGTAATGTTG
CAAAATGAATGTACTCAGACATTCTTAATTTTTACTTAGGGCAGACCAACTCTTTGAGTCTCTCTTGGACTTATATATACAGATATCTTA
AGAGTGGGAATGTAAAGCATAACCTAATTCTCTTTCCTATAGAGATTCTATTTTATTTAAAATCTATTTTTACACTAGTTAGAATCCTGC
TGTTTTGGCCAAGTACTTGTCTTGCATGTCTGACCTTGCAGAAGCTGGGGTGGATCATAGCATACTAATGAAGAGAATTAGAAGTAGTTT
ACAAAGCTCGCTCACTCCTCATTTCTCTGTGATCCCTTCTATCCAGTGGCCCCACCACCACCTGGGAAAACAGATTTTTCAGTACAGGTG
GGATAAATGCTCTGAAAGGCTGTGCCCAGAGGAATGAGCAAATAGGCAAGTGTTTCCAAACTACTTGGAGGTTTACAAAAAATATGTCCC
AGAAAAAAAAAAAATCTTACCAAGATACGTAAAGAAAAAAAAATTTTTTTTTAAACAGTCAAAGAGTCATGTTTGAATTTCACAAAATCA
CATCAGACAGAAGTTGTTTTCTTCAGGAGGGAAATGAACCACTTAATATACCCATACTACCTTGAACAATGAAATTGAATTAAAATAGCC

>8416_8416_5_ATXN2-BRAP_ATXN2_chr12_111947353_ENST00000389153_BRAP_chr12_112087846_ENST00000419234_length(amino acids)=719AA_BP=562
MGRGRNSNKGLPQSTISFDGIYANMRMVHILTSVVGSKCEVQVKNGGIYEGVFKTYSPKCDLVLDAAHEKSTESSSGPKREEIMESILFK
CSDFVVVQFKDMDSSYAKRDAFTDSAISAKVNGEHKEKDLEPWDAGELTANEELEALENDVSNGWDPNDMFRYNEENYGVVSTYDSSLSS
YTVPLERDNSEEFLKREARANQLAEEIESSAQYKARVALENDDRSEEEKYTAVQRNSSEREGHSINTRENKYIPPGQRNREVISWGSGRQ
NSPRMGQPGSGSMPSRSTSHTSDFNPNSGSDQRVVNGGVPWPSPCPSPSSRPPSRYQSGPNSLPPRAATPTRPPSRPPSRPSRPPSHPSA
HGSPAPVSTMPKRMSSEGPPRMSPKAQRHPRNHRVSAGRGSISSGLEFVSHNPPSEAATPPVARTSPSGGTWSSVVSGVPRLSPKTHRPR
SPRQNSIGNTPSGPVLASPQAGIIPTEAVAMPIPAASPTPASPASNRAVTPSSEAKDSRLQDQRQNSPAGNKENIKPNETSPSFSKAENK
GISPVVSEHRKQIDDLKKFKNDFRINNMKTKFKETIEKCDNLEHKLNDLLKEKQSVERKCTQLNTKVAKLTNELKEEQEMNKCLRANQVL

--------------------------------------------------------------
>8416_8416_6_ATXN2-BRAP_ATXN2_chr12_111947353_ENST00000389153_BRAP_chr12_112087846_ENST00000539060_length(transcript)=2451nt_BP=1723nt
CGCGGCGACCTCCGGCGGCGGGAGGCCCGGCCTGGGCAGAGGTCGAAACAGTAACAAAGGACTGCCTCAGTCTACGATTTCTTTTGATGG
AATCTATGCAAATATGAGGATGGTTCATATACTTACATCAGTTGTTGGCTCCAAATGTGAAGTACAAGTGAAAAATGGAGGTATATATGA
AGGAGTTTTTAAAACTTACAGTCCGAAGTGTGATTTGGTACTTGATGCCGCACATGAGAAAAGTACAGAATCCAGTTCGGGGCCGAAACG
TGAAGAAATAATGGAGAGTATTTTGTTCAAATGTTCAGACTTTGTTGTGGTACAGTTTAAAGATATGGACTCCAGTTATGCAAAAAGAGA
TGCTTTTACTGACTCTGCTATCAGTGCTAAAGTGAATGGCGAACACAAAGAGAAGGACCTGGAGCCCTGGGATGCAGGTGAACTCACAGC
CAATGAGGAACTTGAGGCTTTGGAAAATGACGTATCTAATGGATGGGATCCCAATGATATGTTTCGATATAATGAAGAAAATTATGGTGT
AGTGTCTACGTATGATAGCAGTTTATCTTCGTATACAGTGCCCTTAGAAAGAGATAACTCAGAAGAATTTTTAAAACGGGAAGCAAGGGC
AAACCAGTTAGCAGAAGAAATTGAGTCAAGTGCCCAGTACAAAGCTCGAGTGGCCCTGGAAAATGATGATAGGAGTGAGGAAGAAAAATA
CACAGCAGTTCAGAGAAATTCCAGTGAACGTGAGGGGCACAGCATAAACACTAGGGAAAATAAATATATTCCTCCTGGACAAAGAAATAG
AGAAGTCATATCCTGGGGAAGTGGGAGACAGAATTCACCGCGTATGGGCCAGCCTGGATCGGGCTCCATGCCATCAAGATCCACTTCTCA
CACTTCAGATTTCAACCCGAATTCTGGTTCAGACCAAAGAGTAGTTAATGGAGGTGTTCCCTGGCCATCGCCTTGCCCATCTCCTTCCTC
TCGCCCACCTTCTCGCTACCAGTCAGGTCCCAACTCTCTTCCACCTCGGGCAGCCACCCCTACACGGCCGCCCTCCAGGCCCCCCTCGCG
GCCATCCAGACCCCCGTCTCACCCCTCTGCTCATGGTTCTCCAGCTCCTGTCTCTACTATGCCTAAACGCATGTCTTCAGAAGGGCCTCC
AAGGATGTCCCCAAAGGCCCAGCGACATCCTCGAAATCACAGAGTTTCTGCTGGGAGGGGTTCCATATCCAGTGGCCTAGAATTTGTATC
CCACAACCCACCCAGTGAAGCAGCTACTCCTCCAGTAGCAAGGACCAGTCCCTCGGGGGGAACGTGGTCATCAGTGGTCAGTGGGGTTCC
AAGATTATCCCCTAAAACTCATAGACCCAGGTCTCCCAGACAGAACAGTATTGGAAATACCCCCAGTGGGCCAGTTCTTGCTTCTCCCCA
AGCTGGTATTATTCCAACTGAAGCTGTTGCCATGCCTATTCCAGCTGCATCTCCTACGCCTGCTAGTCCTGCATCGAACAGAGCTGTTAC
CCCTTCTAGTGAGGCTAAAGATTCCAGGCTTCAAGATCAGAGGCAGAACTCTCCTGCAGGGAATAAAGAAAATATTAAACCCAATGAAAC
ATCACCTAGCTTCTCAAAAGCTGAAAACAAAGGTATATCACCAGTTGTTTCTGAACATAGAAAACAGATTGATGATTTAAAGAAATTTAA
GAATGATTTTAGGATTAACAACATGAAGACCAAGTTTAAAGAAACAATTGAGAAGTGTGATAATCTAGAGCACAAACTAAATGATCTCCT
AAAAGAAAAGCAGTCTGTGGAAAGAAAGTGCACTCAGCTAAACACAAAAGTGGCCAAACTCACCAACGAGCTCAAAGAGGAGCAGGAAAT
GAACAAGTGTTTGCGAGCCAACCAAGTCCTCCTGCAGAACAAGCTAAAAGAGGAGGAGAGGGTGCTGAAGGAGACCTGTGACCAAAAAGA
TCTGCAGATCACCGAGATCCAGGAGCAGCTGCGTGACGTCATGTTCTACCTGGAGACACAGCAGAAGATCAACCATCTGCCTGCCGAGAC
CCGGCAGGAAATCCAGGAGGGACAGATCAACATCGCCATGGCCTCGGCCTCGAGCCCTGCCTCTTCGGGGGGCAGTGGGAAGTTGCCCTC
CAGGAAGGGCCGCAGCAAGAGGGGCAAGTGACCTTCAGAGCAACAGACATCCCTGAGACTGTTCTCCCTGACACTGTGAGAGTGTGCTGG
GACCTTCAGCTAAATGTGAGGGTGGGCCCTAATAAGTACAAGTGAGGATCAAGCCACAGTTGTTTGGCTCTTTCATTTGCTAGTGTGTGA
TGTAGTGAATGTAAAGGGTGCTGACTGGAGAGCTGATAGAAAGGCGCTGCGTTCGAAAAGGTCTTAAGAGTTCACTAACCTCACATTCTA

>8416_8416_6_ATXN2-BRAP_ATXN2_chr12_111947353_ENST00000389153_BRAP_chr12_112087846_ENST00000539060_length(amino acids)=719AA_BP=562
MGRGRNSNKGLPQSTISFDGIYANMRMVHILTSVVGSKCEVQVKNGGIYEGVFKTYSPKCDLVLDAAHEKSTESSSGPKREEIMESILFK
CSDFVVVQFKDMDSSYAKRDAFTDSAISAKVNGEHKEKDLEPWDAGELTANEELEALENDVSNGWDPNDMFRYNEENYGVVSTYDSSLSS
YTVPLERDNSEEFLKREARANQLAEEIESSAQYKARVALENDDRSEEEKYTAVQRNSSEREGHSINTRENKYIPPGQRNREVISWGSGRQ
NSPRMGQPGSGSMPSRSTSHTSDFNPNSGSDQRVVNGGVPWPSPCPSPSSRPPSRYQSGPNSLPPRAATPTRPPSRPPSRPSRPPSHPSA
HGSPAPVSTMPKRMSSEGPPRMSPKAQRHPRNHRVSAGRGSISSGLEFVSHNPPSEAATPPVARTSPSGGTWSSVVSGVPRLSPKTHRPR
SPRQNSIGNTPSGPVLASPQAGIIPTEAVAMPIPAASPTPASPASNRAVTPSSEAKDSRLQDQRQNSPAGNKENIKPNETSPSFSKAENK
GISPVVSEHRKQIDDLKKFKNDFRINNMKTKFKETIEKCDNLEHKLNDLLKEKQSVERKCTQLNTKVAKLTNELKEEQEMNKCLRANQVL

--------------------------------------------------------------
>8416_8416_7_ATXN2-BRAP_ATXN2_chr12_111947353_ENST00000535949_BRAP_chr12_112087846_ENST00000327551_length(transcript)=2259nt_BP=1674nt
CCCGAGAAAGCAACCCAGCGCGCCGCCCGCTCCTCACGTGTCCCTCCCGGCCCCGGGGCCACCTCACGTTCTGCTTCCGTCTGACCCCTC
CGACTTCCGATTTCTTTTGATGGAATCTATGCAAATATGAGGATGGTTCATATACTTACATCAGTTGTTTGTGATTTGGTACTTGATGCC
GCACATGAGAAAAGTACAGAATCCAGTTCGGGGCCGAAACGTGAAGAAATAATGGAGAGTATTTTGTTCAAATGTTCAGACTTTGTTGTG
GTACAGTTTAAAGATATGGACTCCAGTTATGCAAAAAGAGATGCTTTTACTGACTCTGCTATCAGTGCTAAAGTGAATGGCGAACACAAA
GAGAAGGACCTGGAGCCCTGGGATGCAGGTGAACTCACAGCCAATGAGGAACTTGAGGCTTTGGAAAATGACGTATCTAATGGATGGGAT
CCCAATGATATGTTTCGATATAATGAAGAAAATTATGGTGTAGTGTCTACGTATGATAGCAGTTTATCTTCGTATACAGTGCCCTTAGAA
AGAGATAACTCAGAAGAATTTTTAAAACGGGAAGCAAGGGCAAACCAGTTAGCAGAAGAAATTGAGTCAAGTGCCCAGTACAAAGCTCGA
GTGGCCCTGGAAAATGATGATAGGAGTGAGGAAGAAAAATACACAGCAGTTCAGAGAAATTCCAGTGAACGTGAGGGGCACAGCATAAAC
ACTAGGGAAAATAAATATATTCCTCCTGGACAAAGAAATAGAGAAGTCATATCCTGGGGAAGTGGGAGACAGAATTCACCGCGTATGGGC
CAGCCTGGATCGGGCTCCATGCCATCAAGATCCACTTCTCACACTTCAGATTTCAACCCGAATTCTGGTTCAGACCAAAGAGTAGTTAAT
GGAGGTGTTCCCTGGCCATCGCCTTGCCCATCTCCTTCCTCTCGCCCACCTTCTCGCTACCAGTCAGGTCCCAACTCTCTTCCACCTCGG
GCAGCCACCCCTACACGGCCGCCCTCCAGGCCCCCCTCGCGGCCATCCAGACCCCCGTCTCACCCCTCTGCTCATGGTTCTCCAGCTCCT
GTCTCTACTATGCCTAAACGCATGTCTTCAGAAGGGCCTCCAAGGATGTCCCCAAAGGCCCAGCGACATCCTCGAAATCACAGAGTTTCT
GCTGGGAGGGGTTCCATATCCAGTGGCCTAGAATTTGTATCCCACAACCCACCCAGTGAAGCAGCTACTCCTCCAGTAGCAAGGACCAGT
CCCTCGGGGGGAACGTGGTCATCAGTGGTCAGTGGGGTTCCAAGATTATCCCCTAAAACTCATAGACCCAGGTCTCCCAGACAGAACAGT
ATTGGAAATACCCCCAGTGGGCCAGTTCTTGCTTCTCCCCAAGCTGGTATTATTCCAACTGAAGCTGTTGCCATGCCTATTCCAGCTGCA
TCTCCTACGCCTGCTAGTCCTGCATCGAACAGAGCTGTTACCCCTTCTAGTGAGGCTAAAGATTCCAGGCTTCAAGATCAGAGGCAGAAC
TCTCCTGCAGGGAATAAAGAAAATATTAAACCCAATGAAACATCACCTAGCTTCTCAAAAGCTGAAAACAAAGGTATATCACCAGTTGTT
TCTGAACATAGAAAACAGATTGATGATTTAAAGAAATTTAAGAATGATTTTAGGATTAACAACATGAAGACCAAGTTTAAAGAAACAATT
GAGAAGTGTGATAATCTAGAGCACAAACTAAATGATCTCCTAAAAGAAAAGCAGTCTGTGGAAAGAAAGTGCACTCAGCTAAACACAAAA
GTGGCCAAACTCACCAACGAGCTCAAAGAGGAGCAGGAAATGAACAAGTGTTTGCGAGCCAACCAAGTCCTCCTGCAGAACAAGCTAAAA
GAGGAGGAGAGGGTGCTGAAGGAGACCTGTGACCAAAAAGATCTGCAGATCACCGAGATCCAGGAGCAGCTGCGTGACGTCATGTTCTAC
CTGGAGACACAGCAGAAGATCAACCATCTGCCTGCCGAGACCCGGCAGGAAATCCAGGAGGGACAGATCAACATCGCCATGGCCTCGGCC
TCGAGCCCTGCCTCTTCGGGGGGCAGTGGGAAGTTGCCCTCCAGGAAGGGCCGCAGCAAGAGGGGCAAGTGACCTTCAGAGCAACAGACA
TCCCTGAGACTGTTCTCCCTGACACTGTGAGAGTGTGCTGGGACCTTCAGCTAAATGTGAGGGTGGGCCCTAATAAGTACAAGTGAGGAT

>8416_8416_7_ATXN2-BRAP_ATXN2_chr12_111947353_ENST00000535949_BRAP_chr12_112087846_ENST00000327551_length(amino acids)=671AA_BP=514
MRMVHILTSVVCDLVLDAAHEKSTESSSGPKREEIMESILFKCSDFVVVQFKDMDSSYAKRDAFTDSAISAKVNGEHKEKDLEPWDAGEL
TANEELEALENDVSNGWDPNDMFRYNEENYGVVSTYDSSLSSYTVPLERDNSEEFLKREARANQLAEEIESSAQYKARVALENDDRSEEE
KYTAVQRNSSEREGHSINTRENKYIPPGQRNREVISWGSGRQNSPRMGQPGSGSMPSRSTSHTSDFNPNSGSDQRVVNGGVPWPSPCPSP
SSRPPSRYQSGPNSLPPRAATPTRPPSRPPSRPSRPPSHPSAHGSPAPVSTMPKRMSSEGPPRMSPKAQRHPRNHRVSAGRGSISSGLEF
VSHNPPSEAATPPVARTSPSGGTWSSVVSGVPRLSPKTHRPRSPRQNSIGNTPSGPVLASPQAGIIPTEAVAMPIPAASPTPASPASNRA
VTPSSEAKDSRLQDQRQNSPAGNKENIKPNETSPSFSKAENKGISPVVSEHRKQIDDLKKFKNDFRINNMKTKFKETIEKCDNLEHKLND
LLKEKQSVERKCTQLNTKVAKLTNELKEEQEMNKCLRANQVLLQNKLKEEERVLKETCDQKDLQITEIQEQLRDVMFYLETQQKINHLPA

--------------------------------------------------------------
>8416_8416_8_ATXN2-BRAP_ATXN2_chr12_111947353_ENST00000535949_BRAP_chr12_112087846_ENST00000419234_length(transcript)=4195nt_BP=1674nt
CCCGAGAAAGCAACCCAGCGCGCCGCCCGCTCCTCACGTGTCCCTCCCGGCCCCGGGGCCACCTCACGTTCTGCTTCCGTCTGACCCCTC
CGACTTCCGATTTCTTTTGATGGAATCTATGCAAATATGAGGATGGTTCATATACTTACATCAGTTGTTTGTGATTTGGTACTTGATGCC
GCACATGAGAAAAGTACAGAATCCAGTTCGGGGCCGAAACGTGAAGAAATAATGGAGAGTATTTTGTTCAAATGTTCAGACTTTGTTGTG
GTACAGTTTAAAGATATGGACTCCAGTTATGCAAAAAGAGATGCTTTTACTGACTCTGCTATCAGTGCTAAAGTGAATGGCGAACACAAA
GAGAAGGACCTGGAGCCCTGGGATGCAGGTGAACTCACAGCCAATGAGGAACTTGAGGCTTTGGAAAATGACGTATCTAATGGATGGGAT
CCCAATGATATGTTTCGATATAATGAAGAAAATTATGGTGTAGTGTCTACGTATGATAGCAGTTTATCTTCGTATACAGTGCCCTTAGAA
AGAGATAACTCAGAAGAATTTTTAAAACGGGAAGCAAGGGCAAACCAGTTAGCAGAAGAAATTGAGTCAAGTGCCCAGTACAAAGCTCGA
GTGGCCCTGGAAAATGATGATAGGAGTGAGGAAGAAAAATACACAGCAGTTCAGAGAAATTCCAGTGAACGTGAGGGGCACAGCATAAAC
ACTAGGGAAAATAAATATATTCCTCCTGGACAAAGAAATAGAGAAGTCATATCCTGGGGAAGTGGGAGACAGAATTCACCGCGTATGGGC
CAGCCTGGATCGGGCTCCATGCCATCAAGATCCACTTCTCACACTTCAGATTTCAACCCGAATTCTGGTTCAGACCAAAGAGTAGTTAAT
GGAGGTGTTCCCTGGCCATCGCCTTGCCCATCTCCTTCCTCTCGCCCACCTTCTCGCTACCAGTCAGGTCCCAACTCTCTTCCACCTCGG
GCAGCCACCCCTACACGGCCGCCCTCCAGGCCCCCCTCGCGGCCATCCAGACCCCCGTCTCACCCCTCTGCTCATGGTTCTCCAGCTCCT
GTCTCTACTATGCCTAAACGCATGTCTTCAGAAGGGCCTCCAAGGATGTCCCCAAAGGCCCAGCGACATCCTCGAAATCACAGAGTTTCT
GCTGGGAGGGGTTCCATATCCAGTGGCCTAGAATTTGTATCCCACAACCCACCCAGTGAAGCAGCTACTCCTCCAGTAGCAAGGACCAGT
CCCTCGGGGGGAACGTGGTCATCAGTGGTCAGTGGGGTTCCAAGATTATCCCCTAAAACTCATAGACCCAGGTCTCCCAGACAGAACAGT
ATTGGAAATACCCCCAGTGGGCCAGTTCTTGCTTCTCCCCAAGCTGGTATTATTCCAACTGAAGCTGTTGCCATGCCTATTCCAGCTGCA
TCTCCTACGCCTGCTAGTCCTGCATCGAACAGAGCTGTTACCCCTTCTAGTGAGGCTAAAGATTCCAGGCTTCAAGATCAGAGGCAGAAC
TCTCCTGCAGGGAATAAAGAAAATATTAAACCCAATGAAACATCACCTAGCTTCTCAAAAGCTGAAAACAAAGGTATATCACCAGTTGTT
TCTGAACATAGAAAACAGATTGATGATTTAAAGAAATTTAAGAATGATTTTAGGATTAACAACATGAAGACCAAGTTTAAAGAAACAATT
GAGAAGTGTGATAATCTAGAGCACAAACTAAATGATCTCCTAAAAGAAAAGCAGTCTGTGGAAAGAAAGTGCACTCAGCTAAACACAAAA
GTGGCCAAACTCACCAACGAGCTCAAAGAGGAGCAGGAAATGAACAAGTGTTTGCGAGCCAACCAAGTCCTCCTGCAGAACAAGCTAAAA
GAGGAGGAGAGGGTGCTGAAGGAGACCTGTGACCAAAAAGATCTGCAGATCACCGAGATCCAGGAGCAGCTGCGTGACGTCATGTTCTAC
CTGGAGACACAGCAGAAGATCAACCATCTGCCTGCCGAGACCCGGCAGGAAATCCAGGAGGGACAGATCAACATCGCCATGGCCTCGGCC
TCGAGCCCTGCCTCTTCGGGGGGCAGTGGGAAGTTGCCCTCCAGGAAGGGCCGCAGCAAGAGGGGCAAGTGACCTTCAGAGCAACAGACA
TCCCTGAGACTGTTCTCCCTGACACTGTGAGAGTGTGCTGGGACCTTCAGCTAAATGTGAGGGTGGGCCCTAATAAGTACAAGTGAGGAT
CAAGCCACAGTTGTTTGGCTCTTTCATTTGCTAGTGTGTGATGTAGTGAATGTAAAGGGTGCTGACTGGAGAGCTGATAGAAAGGCGCTG
CGTTCGAAAAGGTCTTAAGAGTTCACTAACCTCACATTCTAATGACCATTTTGCCTTCCTGCTTGGTAGAAGCCCCAACTCTGCTGTGCA
TTTTTCCATTGTATTTATGGAGTTGGCGTATTTGACATTCAGTTCTGGGGTAGGTTTAAGATGTTAAGTTATTTCTTGTAACCTCAAAGG
TAAGGTTATCTAGCACTAAAGCACCAAACCTCTCTGAGGGCATAACAGCTGCTTTAAAGAGAGGTTTCCATTGGCTATTAAGGAGTTATG
AAAACTCCCTAGCAATAGTGTCATATCATTATCATCTCCCCCTTCCTCTGGGGAGTGGAAGAATTGCTTGAATGTTATCTGAAAAGAGGC
CTGGTAGTAAACCAGGCCCTGGCTCTTTACCAGCAGTCATCTCTTCTTGCTCTGGGGCCAGCCAGGAAAAACAAACAACCCGGGGCACAT
TGGGTAGACTCAGTGTAGGAAAAATGGTGGCAGCTCCACTGTTTATTTTTGGTGACTTCGTACATCATTATGAACCGCAATTAAGGAGGA
GGCTTAATGGCTGTTCCCAAACTCAAATCTCAGAGTGGGTATCCTAGCATCTAGCAAGACTGAGTGGGGAGATTTCTCATCCGTGTGAAA
ATGTAGAGTGAGGCCTCTGACTAGCTAATTGTGTATTTTGTTGGGTTTAGTATTTTCTAAATGTTTACAAAATATTGGGCTGCATGTTCA
GGTTGCAGCTAGAGGGAGCTTGGGCAGATTTTCAATTACGCTTTCAAGATATAACCAAAAGCTGTTTCTAAATCCTAAAATTAGAATTTC
AACAGAGCCCCCTTTAGAACAGTCATATAACGCTTGTGTGGGCCAACAGAGGGGCTGTGTACTCTCTCTGGAACCATAAATGTCAAATAA
TTTATAACCTGCAGTAATTGAGCAAACTTAAAATAAGACCTGTGTTGGAATTTAGTTTCTTGAAGAGGTAGAGGGATAGGTTAGTAAGAT
GTATTGTTAAACAACAGGTTTTAGTTTTTGCTTTATAATTAGCCACAGGTTTTCAAATGATCACATTTCAGAATAGGTTTTTAGCCTGTA
ATTAGGCCTCATCCCCTTTGACCTAAATGTCTTACATGTTACTTGTTAGCACATCAACTGTATCACTAATCACCATCTGTTTTTGTGGGA
TGTGCTGCAGCATTTCCCAAAAAACTTTACGTGTAATGTTGCAAAATGAATGTACTCAGACATTCTTAATTTTTACTTAGGGCAGACCAA
CTCTTTGAGTCTCTCTTGGACTTATATATACAGATATCTTAAGAGTGGGAATGTAAAGCATAACCTAATTCTCTTTCCTATAGAGATTCT
ATTTTATTTAAAATCTATTTTTACACTAGTTAGAATCCTGCTGTTTTGGCCAAGTACTTGTCTTGCATGTCTGACCTTGCAGAAGCTGGG
GTGGATCATAGCATACTAATGAAGAGAATTAGAAGTAGTTTACAAAGCTCGCTCACTCCTCATTTCTCTGTGATCCCTTCTATCCAGTGG
CCCCACCACCACCTGGGAAAACAGATTTTTCAGTACAGGTGGGATAAATGCTCTGAAAGGCTGTGCCCAGAGGAATGAGCAAATAGGCAA
GTGTTTCCAAACTACTTGGAGGTTTACAAAAAATATGTCCCAGAAAAAAAAAAAATCTTACCAAGATACGTAAAGAAAAAAAAATTTTTT
TTTAAACAGTCAAAGAGTCATGTTTGAATTTCACAAAATCACATCAGACAGAAGTTGTTTTCTTCAGGAGGGAAATGAACCACTTAATAT

>8416_8416_8_ATXN2-BRAP_ATXN2_chr12_111947353_ENST00000535949_BRAP_chr12_112087846_ENST00000419234_length(amino acids)=671AA_BP=514
MRMVHILTSVVCDLVLDAAHEKSTESSSGPKREEIMESILFKCSDFVVVQFKDMDSSYAKRDAFTDSAISAKVNGEHKEKDLEPWDAGEL
TANEELEALENDVSNGWDPNDMFRYNEENYGVVSTYDSSLSSYTVPLERDNSEEFLKREARANQLAEEIESSAQYKARVALENDDRSEEE
KYTAVQRNSSEREGHSINTRENKYIPPGQRNREVISWGSGRQNSPRMGQPGSGSMPSRSTSHTSDFNPNSGSDQRVVNGGVPWPSPCPSP
SSRPPSRYQSGPNSLPPRAATPTRPPSRPPSRPSRPPSHPSAHGSPAPVSTMPKRMSSEGPPRMSPKAQRHPRNHRVSAGRGSISSGLEF
VSHNPPSEAATPPVARTSPSGGTWSSVVSGVPRLSPKTHRPRSPRQNSIGNTPSGPVLASPQAGIIPTEAVAMPIPAASPTPASPASNRA
VTPSSEAKDSRLQDQRQNSPAGNKENIKPNETSPSFSKAENKGISPVVSEHRKQIDDLKKFKNDFRINNMKTKFKETIEKCDNLEHKLND
LLKEKQSVERKCTQLNTKVAKLTNELKEEQEMNKCLRANQVLLQNKLKEEERVLKETCDQKDLQITEIQEQLRDVMFYLETQQKINHLPA

--------------------------------------------------------------
>8416_8416_9_ATXN2-BRAP_ATXN2_chr12_111947353_ENST00000535949_BRAP_chr12_112087846_ENST00000539060_length(transcript)=2402nt_BP=1674nt
CCCGAGAAAGCAACCCAGCGCGCCGCCCGCTCCTCACGTGTCCCTCCCGGCCCCGGGGCCACCTCACGTTCTGCTTCCGTCTGACCCCTC
CGACTTCCGATTTCTTTTGATGGAATCTATGCAAATATGAGGATGGTTCATATACTTACATCAGTTGTTTGTGATTTGGTACTTGATGCC
GCACATGAGAAAAGTACAGAATCCAGTTCGGGGCCGAAACGTGAAGAAATAATGGAGAGTATTTTGTTCAAATGTTCAGACTTTGTTGTG
GTACAGTTTAAAGATATGGACTCCAGTTATGCAAAAAGAGATGCTTTTACTGACTCTGCTATCAGTGCTAAAGTGAATGGCGAACACAAA
GAGAAGGACCTGGAGCCCTGGGATGCAGGTGAACTCACAGCCAATGAGGAACTTGAGGCTTTGGAAAATGACGTATCTAATGGATGGGAT
CCCAATGATATGTTTCGATATAATGAAGAAAATTATGGTGTAGTGTCTACGTATGATAGCAGTTTATCTTCGTATACAGTGCCCTTAGAA
AGAGATAACTCAGAAGAATTTTTAAAACGGGAAGCAAGGGCAAACCAGTTAGCAGAAGAAATTGAGTCAAGTGCCCAGTACAAAGCTCGA
GTGGCCCTGGAAAATGATGATAGGAGTGAGGAAGAAAAATACACAGCAGTTCAGAGAAATTCCAGTGAACGTGAGGGGCACAGCATAAAC
ACTAGGGAAAATAAATATATTCCTCCTGGACAAAGAAATAGAGAAGTCATATCCTGGGGAAGTGGGAGACAGAATTCACCGCGTATGGGC
CAGCCTGGATCGGGCTCCATGCCATCAAGATCCACTTCTCACACTTCAGATTTCAACCCGAATTCTGGTTCAGACCAAAGAGTAGTTAAT
GGAGGTGTTCCCTGGCCATCGCCTTGCCCATCTCCTTCCTCTCGCCCACCTTCTCGCTACCAGTCAGGTCCCAACTCTCTTCCACCTCGG
GCAGCCACCCCTACACGGCCGCCCTCCAGGCCCCCCTCGCGGCCATCCAGACCCCCGTCTCACCCCTCTGCTCATGGTTCTCCAGCTCCT
GTCTCTACTATGCCTAAACGCATGTCTTCAGAAGGGCCTCCAAGGATGTCCCCAAAGGCCCAGCGACATCCTCGAAATCACAGAGTTTCT
GCTGGGAGGGGTTCCATATCCAGTGGCCTAGAATTTGTATCCCACAACCCACCCAGTGAAGCAGCTACTCCTCCAGTAGCAAGGACCAGT
CCCTCGGGGGGAACGTGGTCATCAGTGGTCAGTGGGGTTCCAAGATTATCCCCTAAAACTCATAGACCCAGGTCTCCCAGACAGAACAGT
ATTGGAAATACCCCCAGTGGGCCAGTTCTTGCTTCTCCCCAAGCTGGTATTATTCCAACTGAAGCTGTTGCCATGCCTATTCCAGCTGCA
TCTCCTACGCCTGCTAGTCCTGCATCGAACAGAGCTGTTACCCCTTCTAGTGAGGCTAAAGATTCCAGGCTTCAAGATCAGAGGCAGAAC
TCTCCTGCAGGGAATAAAGAAAATATTAAACCCAATGAAACATCACCTAGCTTCTCAAAAGCTGAAAACAAAGGTATATCACCAGTTGTT
TCTGAACATAGAAAACAGATTGATGATTTAAAGAAATTTAAGAATGATTTTAGGATTAACAACATGAAGACCAAGTTTAAAGAAACAATT
GAGAAGTGTGATAATCTAGAGCACAAACTAAATGATCTCCTAAAAGAAAAGCAGTCTGTGGAAAGAAAGTGCACTCAGCTAAACACAAAA
GTGGCCAAACTCACCAACGAGCTCAAAGAGGAGCAGGAAATGAACAAGTGTTTGCGAGCCAACCAAGTCCTCCTGCAGAACAAGCTAAAA
GAGGAGGAGAGGGTGCTGAAGGAGACCTGTGACCAAAAAGATCTGCAGATCACCGAGATCCAGGAGCAGCTGCGTGACGTCATGTTCTAC
CTGGAGACACAGCAGAAGATCAACCATCTGCCTGCCGAGACCCGGCAGGAAATCCAGGAGGGACAGATCAACATCGCCATGGCCTCGGCC
TCGAGCCCTGCCTCTTCGGGGGGCAGTGGGAAGTTGCCCTCCAGGAAGGGCCGCAGCAAGAGGGGCAAGTGACCTTCAGAGCAACAGACA
TCCCTGAGACTGTTCTCCCTGACACTGTGAGAGTGTGCTGGGACCTTCAGCTAAATGTGAGGGTGGGCCCTAATAAGTACAAGTGAGGAT
CAAGCCACAGTTGTTTGGCTCTTTCATTTGCTAGTGTGTGATGTAGTGAATGTAAAGGGTGCTGACTGGAGAGCTGATAGAAAGGCGCTG

>8416_8416_9_ATXN2-BRAP_ATXN2_chr12_111947353_ENST00000535949_BRAP_chr12_112087846_ENST00000539060_length(amino acids)=671AA_BP=514
MRMVHILTSVVCDLVLDAAHEKSTESSSGPKREEIMESILFKCSDFVVVQFKDMDSSYAKRDAFTDSAISAKVNGEHKEKDLEPWDAGEL
TANEELEALENDVSNGWDPNDMFRYNEENYGVVSTYDSSLSSYTVPLERDNSEEFLKREARANQLAEEIESSAQYKARVALENDDRSEEE
KYTAVQRNSSEREGHSINTRENKYIPPGQRNREVISWGSGRQNSPRMGQPGSGSMPSRSTSHTSDFNPNSGSDQRVVNGGVPWPSPCPSP
SSRPPSRYQSGPNSLPPRAATPTRPPSRPPSRPSRPPSHPSAHGSPAPVSTMPKRMSSEGPPRMSPKAQRHPRNHRVSAGRGSISSGLEF
VSHNPPSEAATPPVARTSPSGGTWSSVVSGVPRLSPKTHRPRSPRQNSIGNTPSGPVLASPQAGIIPTEAVAMPIPAASPTPASPASNRA
VTPSSEAKDSRLQDQRQNSPAGNKENIKPNETSPSFSKAENKGISPVVSEHRKQIDDLKKFKNDFRINNMKTKFKETIEKCDNLEHKLND
LLKEKQSVERKCTQLNTKVAKLTNELKEEQEMNKCLRANQVLLQNKLKEEERVLKETCDQKDLQITEIQEQLRDVMFYLETQQKINHLPA

--------------------------------------------------------------
>8416_8416_10_ATXN2-BRAP_ATXN2_chr12_111947353_ENST00000608853_BRAP_chr12_112087846_ENST00000327551_length(transcript)=2836nt_BP=2251nt
TCCCCCGCCCGGCCCCGGCCCCCCTCCCTCCCGGCAGAGCTCGCCTCCCTCCGCCTCAGACTGTTTTGGTAGCAACGGCAACGGCGGCGG
CGCGTTTCGGCCCGGCTCCCGGCGGCTCCTTGGTCTCGGCGGGCCTCCCCGCCCCTTCGTCGTCCTCCTTCTCCCCCTCGCCAGCCCGGG
CGCCCCTCCGGCCGCGCCAACCCGCGCCTCCCCGCTCGGCGCCCGCGCGTCCCCGCCGCGTTCCGGCGTCTCCTTGGCGCGCCCGGCTCC
CGGCTGTCCCCGCCCGGCGTGCGAGCCGGTGTATGGGCCCCTCACCATGTCGCTGAAGCCCCAGCAGCAGCAGCAGCAGCAGCAGCAGCA
GCAGCAGCAGCAACAGCAGCAGCAGCAGCAGCAGCAGCAGCCGCCGCCCGCGGCTGCCAATGTCCGCAAGCCCGGCGGCAGCGGCCTTCT
AGCGTCGCCCGCCGCCGCGCCTTCGCCGTCCTCGTCCTCGGTCTCCTCGTCCTCGGCCACGGCTCCCTCCTCGGTGGTCGCGGCGACCTC
CGGCGGCGGGAGGCCCGGCCTGGGCAGAGGTCGAAACAGTAACAAAGGACTGCCTCAGTCTACGATTTCTTTTGATGGAATCTATGCAAA
TATGAGGATGGTTCATATACTTACATCAGTTGTTGGCTCCAAATGTGAAGTACAAGTGAAAAATGGAGGTATATATGAAGGAGTTTTTAA
AACTTACAGTCCGAAGTGTGATTTGGTACTTGATGCCGCACATGAGAAAAGTACAGAATCCAGTTCGGGGCCGAAACGTGAAGAAATAAT
GGAGAGTATTTTGTTCAAATGTTCAGACTTTGTTGTGGTACAGTTTAAAGATATGGACTCCAGTTATGCAAAAAGAGATGCTTTTACTGA
CTCTGCTATCAGTGCTAAAGTGAATGGCGAACACAAAGAGAAGGACCTGGAGCCCTGGGATGCAGGTGAACTCACAGCCAATGAGGAACT
TGAGGCTTTGGAAAATGACGTATCTAATGGATGGGATCCCAATGATATGTTTCGATATAATGAAGAAAATTATGGTGTAGTGTCTACGTA
TGATAGCAGTTTATCTTCGTATACAGTGCCCTTAGAAAGAGATAACTCAGAAGAATTTTTAAAACGGGAAGCAAGGGCAAACCAGTTAGC
AGAAGAAATTGAGTCAAGTGCCCAGTACAAAGCTCGAGTGGCCCTGGAAAATGATGATAGGAGTGAGGAAGAAAAATACACAGCAGTTCA
GAGAAATTCCAGTGAACGTGAGGGGCACAGCATAAACACTAGGGAAAATAAATATATTCCTCCTGGACAAAGAAATAGAGAAGTCATATC
CTGGGGAAGTGGGAGACAGAATTCACCGCGTATGGGCCAGCCTGGATCGGGCTCCATGCCATCAAGATCCACTTCTCACACTTCAGATTT
CAACCCGAATTCTGGTTCAGACCAAAGAGTAGTTAATGGAGGTGTTCCCTGGCCATCGCCTTGCCCATCTCCTTCCTCTCGCCCACCTTC
TCGCTACCAGTCAGGTCCCAACTCTCTTCCACCTCGGGCAGCCACCCCTACACGGCCGCCCTCCAGGCCCCCCTCGCGGCCATCCAGACC
CCCGTCTCACCCCTCTGCTCATGGTTCTCCAGCTCCTGTCTCTACTATGCCTAAACGCATGTCTTCAGAAGGGCCTCCAAGGATGTCCCC
AAAGGCCCAGCGACATCCTCGAAATCACAGAGTTTCTGCTGGGAGGGGTTCCATATCCAGTGGCCTAGAATTTGTATCCCACAACCCACC
CAGTGAAGCAGCTACTCCTCCAGTAGCAAGGACCAGTCCCTCGGGGGGAACGTGGTCATCAGTGGTCAGTGGGGTTCCAAGATTATCCCC
TAAAACTCATAGACCCAGGTCTCCCAGACAGAACAGTATTGGAAATACCCCCAGTGGGCCAGTTCTTGCTTCTCCCCAAGCTGGTATTAT
TCCAACTGAAGCTGTTGCCATGCCTATTCCAGCTGCATCTCCTACGCCTGCTAGTCCTGCATCGAACAGAGCTGTTACCCCTTCTAGTGA
GGCTAAAGATTCCAGGCTTCAAGATCAGAGGCAGAACTCTCCTGCAGGGAATAAAGAAAATATTAAACCCAATGAAACATCACCTAGCTT
CTCAAAAGCTGAAAACAAAGGTATATCACCAGTTGTTTCTGAACATAGAAAACAGATTGATGATTTAAAGAAATTTAAGAATGATTTTAG
GATTAACAACATGAAGACCAAGTTTAAAGAAACAATTGAGAAGTGTGATAATCTAGAGCACAAACTAAATGATCTCCTAAAAGAAAAGCA
GTCTGTGGAAAGAAAGTGCACTCAGCTAAACACAAAAGTGGCCAAACTCACCAACGAGCTCAAAGAGGAGCAGGAAATGAACAAGTGTTT
GCGAGCCAACCAAGTCCTCCTGCAGAACAAGCTAAAAGAGGAGGAGAGGGTGCTGAAGGAGACCTGTGACCAAAAAGATCTGCAGATCAC
CGAGATCCAGGAGCAGCTGCGTGACGTCATGTTCTACCTGGAGACACAGCAGAAGATCAACCATCTGCCTGCCGAGACCCGGCAGGAAAT
CCAGGAGGGACAGATCAACATCGCCATGGCCTCGGCCTCGAGCCCTGCCTCTTCGGGGGGCAGTGGGAAGTTGCCCTCCAGGAAGGGCCG
CAGCAAGAGGGGCAAGTGACCTTCAGAGCAACAGACATCCCTGAGACTGTTCTCCCTGACACTGTGAGAGTGTGCTGGGACCTTCAGCTA

>8416_8416_10_ATXN2-BRAP_ATXN2_chr12_111947353_ENST00000608853_BRAP_chr12_112087846_ENST00000327551_length(amino acids)=821AA_BP=664
MARPAPGCPRPACEPVYGPLTMSLKPQQQQQQQQQQQQQQQQQQQQQQQPPPAAANVRKPGGSGLLASPAAAPSPSSSSVSSSSATAPSS
VVAATSGGGRPGLGRGRNSNKGLPQSTISFDGIYANMRMVHILTSVVGSKCEVQVKNGGIYEGVFKTYSPKCDLVLDAAHEKSTESSSGP
KREEIMESILFKCSDFVVVQFKDMDSSYAKRDAFTDSAISAKVNGEHKEKDLEPWDAGELTANEELEALENDVSNGWDPNDMFRYNEENY
GVVSTYDSSLSSYTVPLERDNSEEFLKREARANQLAEEIESSAQYKARVALENDDRSEEEKYTAVQRNSSEREGHSINTRENKYIPPGQR
NREVISWGSGRQNSPRMGQPGSGSMPSRSTSHTSDFNPNSGSDQRVVNGGVPWPSPCPSPSSRPPSRYQSGPNSLPPRAATPTRPPSRPP
SRPSRPPSHPSAHGSPAPVSTMPKRMSSEGPPRMSPKAQRHPRNHRVSAGRGSISSGLEFVSHNPPSEAATPPVARTSPSGGTWSSVVSG
VPRLSPKTHRPRSPRQNSIGNTPSGPVLASPQAGIIPTEAVAMPIPAASPTPASPASNRAVTPSSEAKDSRLQDQRQNSPAGNKENIKPN
ETSPSFSKAENKGISPVVSEHRKQIDDLKKFKNDFRINNMKTKFKETIEKCDNLEHKLNDLLKEKQSVERKCTQLNTKVAKLTNELKEEQ
EMNKCLRANQVLLQNKLKEEERVLKETCDQKDLQITEIQEQLRDVMFYLETQQKINHLPAETRQEIQEGQINIAMASASSPASSGGSGKL

--------------------------------------------------------------
>8416_8416_11_ATXN2-BRAP_ATXN2_chr12_111947353_ENST00000608853_BRAP_chr12_112087846_ENST00000419234_length(transcript)=4772nt_BP=2251nt
TCCCCCGCCCGGCCCCGGCCCCCCTCCCTCCCGGCAGAGCTCGCCTCCCTCCGCCTCAGACTGTTTTGGTAGCAACGGCAACGGCGGCGG
CGCGTTTCGGCCCGGCTCCCGGCGGCTCCTTGGTCTCGGCGGGCCTCCCCGCCCCTTCGTCGTCCTCCTTCTCCCCCTCGCCAGCCCGGG
CGCCCCTCCGGCCGCGCCAACCCGCGCCTCCCCGCTCGGCGCCCGCGCGTCCCCGCCGCGTTCCGGCGTCTCCTTGGCGCGCCCGGCTCC
CGGCTGTCCCCGCCCGGCGTGCGAGCCGGTGTATGGGCCCCTCACCATGTCGCTGAAGCCCCAGCAGCAGCAGCAGCAGCAGCAGCAGCA
GCAGCAGCAGCAACAGCAGCAGCAGCAGCAGCAGCAGCAGCCGCCGCCCGCGGCTGCCAATGTCCGCAAGCCCGGCGGCAGCGGCCTTCT
AGCGTCGCCCGCCGCCGCGCCTTCGCCGTCCTCGTCCTCGGTCTCCTCGTCCTCGGCCACGGCTCCCTCCTCGGTGGTCGCGGCGACCTC
CGGCGGCGGGAGGCCCGGCCTGGGCAGAGGTCGAAACAGTAACAAAGGACTGCCTCAGTCTACGATTTCTTTTGATGGAATCTATGCAAA
TATGAGGATGGTTCATATACTTACATCAGTTGTTGGCTCCAAATGTGAAGTACAAGTGAAAAATGGAGGTATATATGAAGGAGTTTTTAA
AACTTACAGTCCGAAGTGTGATTTGGTACTTGATGCCGCACATGAGAAAAGTACAGAATCCAGTTCGGGGCCGAAACGTGAAGAAATAAT
GGAGAGTATTTTGTTCAAATGTTCAGACTTTGTTGTGGTACAGTTTAAAGATATGGACTCCAGTTATGCAAAAAGAGATGCTTTTACTGA
CTCTGCTATCAGTGCTAAAGTGAATGGCGAACACAAAGAGAAGGACCTGGAGCCCTGGGATGCAGGTGAACTCACAGCCAATGAGGAACT
TGAGGCTTTGGAAAATGACGTATCTAATGGATGGGATCCCAATGATATGTTTCGATATAATGAAGAAAATTATGGTGTAGTGTCTACGTA
TGATAGCAGTTTATCTTCGTATACAGTGCCCTTAGAAAGAGATAACTCAGAAGAATTTTTAAAACGGGAAGCAAGGGCAAACCAGTTAGC
AGAAGAAATTGAGTCAAGTGCCCAGTACAAAGCTCGAGTGGCCCTGGAAAATGATGATAGGAGTGAGGAAGAAAAATACACAGCAGTTCA
GAGAAATTCCAGTGAACGTGAGGGGCACAGCATAAACACTAGGGAAAATAAATATATTCCTCCTGGACAAAGAAATAGAGAAGTCATATC
CTGGGGAAGTGGGAGACAGAATTCACCGCGTATGGGCCAGCCTGGATCGGGCTCCATGCCATCAAGATCCACTTCTCACACTTCAGATTT
CAACCCGAATTCTGGTTCAGACCAAAGAGTAGTTAATGGAGGTGTTCCCTGGCCATCGCCTTGCCCATCTCCTTCCTCTCGCCCACCTTC
TCGCTACCAGTCAGGTCCCAACTCTCTTCCACCTCGGGCAGCCACCCCTACACGGCCGCCCTCCAGGCCCCCCTCGCGGCCATCCAGACC
CCCGTCTCACCCCTCTGCTCATGGTTCTCCAGCTCCTGTCTCTACTATGCCTAAACGCATGTCTTCAGAAGGGCCTCCAAGGATGTCCCC
AAAGGCCCAGCGACATCCTCGAAATCACAGAGTTTCTGCTGGGAGGGGTTCCATATCCAGTGGCCTAGAATTTGTATCCCACAACCCACC
CAGTGAAGCAGCTACTCCTCCAGTAGCAAGGACCAGTCCCTCGGGGGGAACGTGGTCATCAGTGGTCAGTGGGGTTCCAAGATTATCCCC
TAAAACTCATAGACCCAGGTCTCCCAGACAGAACAGTATTGGAAATACCCCCAGTGGGCCAGTTCTTGCTTCTCCCCAAGCTGGTATTAT
TCCAACTGAAGCTGTTGCCATGCCTATTCCAGCTGCATCTCCTACGCCTGCTAGTCCTGCATCGAACAGAGCTGTTACCCCTTCTAGTGA
GGCTAAAGATTCCAGGCTTCAAGATCAGAGGCAGAACTCTCCTGCAGGGAATAAAGAAAATATTAAACCCAATGAAACATCACCTAGCTT
CTCAAAAGCTGAAAACAAAGGTATATCACCAGTTGTTTCTGAACATAGAAAACAGATTGATGATTTAAAGAAATTTAAGAATGATTTTAG
GATTAACAACATGAAGACCAAGTTTAAAGAAACAATTGAGAAGTGTGATAATCTAGAGCACAAACTAAATGATCTCCTAAAAGAAAAGCA
GTCTGTGGAAAGAAAGTGCACTCAGCTAAACACAAAAGTGGCCAAACTCACCAACGAGCTCAAAGAGGAGCAGGAAATGAACAAGTGTTT
GCGAGCCAACCAAGTCCTCCTGCAGAACAAGCTAAAAGAGGAGGAGAGGGTGCTGAAGGAGACCTGTGACCAAAAAGATCTGCAGATCAC
CGAGATCCAGGAGCAGCTGCGTGACGTCATGTTCTACCTGGAGACACAGCAGAAGATCAACCATCTGCCTGCCGAGACCCGGCAGGAAAT
CCAGGAGGGACAGATCAACATCGCCATGGCCTCGGCCTCGAGCCCTGCCTCTTCGGGGGGCAGTGGGAAGTTGCCCTCCAGGAAGGGCCG
CAGCAAGAGGGGCAAGTGACCTTCAGAGCAACAGACATCCCTGAGACTGTTCTCCCTGACACTGTGAGAGTGTGCTGGGACCTTCAGCTA
AATGTGAGGGTGGGCCCTAATAAGTACAAGTGAGGATCAAGCCACAGTTGTTTGGCTCTTTCATTTGCTAGTGTGTGATGTAGTGAATGT
AAAGGGTGCTGACTGGAGAGCTGATAGAAAGGCGCTGCGTTCGAAAAGGTCTTAAGAGTTCACTAACCTCACATTCTAATGACCATTTTG
CCTTCCTGCTTGGTAGAAGCCCCAACTCTGCTGTGCATTTTTCCATTGTATTTATGGAGTTGGCGTATTTGACATTCAGTTCTGGGGTAG
GTTTAAGATGTTAAGTTATTTCTTGTAACCTCAAAGGTAAGGTTATCTAGCACTAAAGCACCAAACCTCTCTGAGGGCATAACAGCTGCT
TTAAAGAGAGGTTTCCATTGGCTATTAAGGAGTTATGAAAACTCCCTAGCAATAGTGTCATATCATTATCATCTCCCCCTTCCTCTGGGG
AGTGGAAGAATTGCTTGAATGTTATCTGAAAAGAGGCCTGGTAGTAAACCAGGCCCTGGCTCTTTACCAGCAGTCATCTCTTCTTGCTCT
GGGGCCAGCCAGGAAAAACAAACAACCCGGGGCACATTGGGTAGACTCAGTGTAGGAAAAATGGTGGCAGCTCCACTGTTTATTTTTGGT
GACTTCGTACATCATTATGAACCGCAATTAAGGAGGAGGCTTAATGGCTGTTCCCAAACTCAAATCTCAGAGTGGGTATCCTAGCATCTA
GCAAGACTGAGTGGGGAGATTTCTCATCCGTGTGAAAATGTAGAGTGAGGCCTCTGACTAGCTAATTGTGTATTTTGTTGGGTTTAGTAT
TTTCTAAATGTTTACAAAATATTGGGCTGCATGTTCAGGTTGCAGCTAGAGGGAGCTTGGGCAGATTTTCAATTACGCTTTCAAGATATA
ACCAAAAGCTGTTTCTAAATCCTAAAATTAGAATTTCAACAGAGCCCCCTTTAGAACAGTCATATAACGCTTGTGTGGGCCAACAGAGGG
GCTGTGTACTCTCTCTGGAACCATAAATGTCAAATAATTTATAACCTGCAGTAATTGAGCAAACTTAAAATAAGACCTGTGTTGGAATTT
AGTTTCTTGAAGAGGTAGAGGGATAGGTTAGTAAGATGTATTGTTAAACAACAGGTTTTAGTTTTTGCTTTATAATTAGCCACAGGTTTT
CAAATGATCACATTTCAGAATAGGTTTTTAGCCTGTAATTAGGCCTCATCCCCTTTGACCTAAATGTCTTACATGTTACTTGTTAGCACA
TCAACTGTATCACTAATCACCATCTGTTTTTGTGGGATGTGCTGCAGCATTTCCCAAAAAACTTTACGTGTAATGTTGCAAAATGAATGT
ACTCAGACATTCTTAATTTTTACTTAGGGCAGACCAACTCTTTGAGTCTCTCTTGGACTTATATATACAGATATCTTAAGAGTGGGAATG
TAAAGCATAACCTAATTCTCTTTCCTATAGAGATTCTATTTTATTTAAAATCTATTTTTACACTAGTTAGAATCCTGCTGTTTTGGCCAA
GTACTTGTCTTGCATGTCTGACCTTGCAGAAGCTGGGGTGGATCATAGCATACTAATGAAGAGAATTAGAAGTAGTTTACAAAGCTCGCT
CACTCCTCATTTCTCTGTGATCCCTTCTATCCAGTGGCCCCACCACCACCTGGGAAAACAGATTTTTCAGTACAGGTGGGATAAATGCTC
TGAAAGGCTGTGCCCAGAGGAATGAGCAAATAGGCAAGTGTTTCCAAACTACTTGGAGGTTTACAAAAAATATGTCCCAGAAAAAAAAAA
AATCTTACCAAGATACGTAAAGAAAAAAAAATTTTTTTTTAAACAGTCAAAGAGTCATGTTTGAATTTCACAAAATCACATCAGACAGAA
GTTGTTTTCTTCAGGAGGGAAATGAACCACTTAATATACCCATACTACCTTGAACAATGAAATTGAATTAAAATAGCCAAACTTTGAAAT

>8416_8416_11_ATXN2-BRAP_ATXN2_chr12_111947353_ENST00000608853_BRAP_chr12_112087846_ENST00000419234_length(amino acids)=821AA_BP=664
MARPAPGCPRPACEPVYGPLTMSLKPQQQQQQQQQQQQQQQQQQQQQQQPPPAAANVRKPGGSGLLASPAAAPSPSSSSVSSSSATAPSS
VVAATSGGGRPGLGRGRNSNKGLPQSTISFDGIYANMRMVHILTSVVGSKCEVQVKNGGIYEGVFKTYSPKCDLVLDAAHEKSTESSSGP
KREEIMESILFKCSDFVVVQFKDMDSSYAKRDAFTDSAISAKVNGEHKEKDLEPWDAGELTANEELEALENDVSNGWDPNDMFRYNEENY
GVVSTYDSSLSSYTVPLERDNSEEFLKREARANQLAEEIESSAQYKARVALENDDRSEEEKYTAVQRNSSEREGHSINTRENKYIPPGQR
NREVISWGSGRQNSPRMGQPGSGSMPSRSTSHTSDFNPNSGSDQRVVNGGVPWPSPCPSPSSRPPSRYQSGPNSLPPRAATPTRPPSRPP
SRPSRPPSHPSAHGSPAPVSTMPKRMSSEGPPRMSPKAQRHPRNHRVSAGRGSISSGLEFVSHNPPSEAATPPVARTSPSGGTWSSVVSG
VPRLSPKTHRPRSPRQNSIGNTPSGPVLASPQAGIIPTEAVAMPIPAASPTPASPASNRAVTPSSEAKDSRLQDQRQNSPAGNKENIKPN
ETSPSFSKAENKGISPVVSEHRKQIDDLKKFKNDFRINNMKTKFKETIEKCDNLEHKLNDLLKEKQSVERKCTQLNTKVAKLTNELKEEQ
EMNKCLRANQVLLQNKLKEEERVLKETCDQKDLQITEIQEQLRDVMFYLETQQKINHLPAETRQEIQEGQINIAMASASSPASSGGSGKL

--------------------------------------------------------------
>8416_8416_12_ATXN2-BRAP_ATXN2_chr12_111947353_ENST00000608853_BRAP_chr12_112087846_ENST00000539060_length(transcript)=2979nt_BP=2251nt
TCCCCCGCCCGGCCCCGGCCCCCCTCCCTCCCGGCAGAGCTCGCCTCCCTCCGCCTCAGACTGTTTTGGTAGCAACGGCAACGGCGGCGG
CGCGTTTCGGCCCGGCTCCCGGCGGCTCCTTGGTCTCGGCGGGCCTCCCCGCCCCTTCGTCGTCCTCCTTCTCCCCCTCGCCAGCCCGGG
CGCCCCTCCGGCCGCGCCAACCCGCGCCTCCCCGCTCGGCGCCCGCGCGTCCCCGCCGCGTTCCGGCGTCTCCTTGGCGCGCCCGGCTCC
CGGCTGTCCCCGCCCGGCGTGCGAGCCGGTGTATGGGCCCCTCACCATGTCGCTGAAGCCCCAGCAGCAGCAGCAGCAGCAGCAGCAGCA
GCAGCAGCAGCAACAGCAGCAGCAGCAGCAGCAGCAGCAGCCGCCGCCCGCGGCTGCCAATGTCCGCAAGCCCGGCGGCAGCGGCCTTCT
AGCGTCGCCCGCCGCCGCGCCTTCGCCGTCCTCGTCCTCGGTCTCCTCGTCCTCGGCCACGGCTCCCTCCTCGGTGGTCGCGGCGACCTC
CGGCGGCGGGAGGCCCGGCCTGGGCAGAGGTCGAAACAGTAACAAAGGACTGCCTCAGTCTACGATTTCTTTTGATGGAATCTATGCAAA
TATGAGGATGGTTCATATACTTACATCAGTTGTTGGCTCCAAATGTGAAGTACAAGTGAAAAATGGAGGTATATATGAAGGAGTTTTTAA
AACTTACAGTCCGAAGTGTGATTTGGTACTTGATGCCGCACATGAGAAAAGTACAGAATCCAGTTCGGGGCCGAAACGTGAAGAAATAAT
GGAGAGTATTTTGTTCAAATGTTCAGACTTTGTTGTGGTACAGTTTAAAGATATGGACTCCAGTTATGCAAAAAGAGATGCTTTTACTGA
CTCTGCTATCAGTGCTAAAGTGAATGGCGAACACAAAGAGAAGGACCTGGAGCCCTGGGATGCAGGTGAACTCACAGCCAATGAGGAACT
TGAGGCTTTGGAAAATGACGTATCTAATGGATGGGATCCCAATGATATGTTTCGATATAATGAAGAAAATTATGGTGTAGTGTCTACGTA
TGATAGCAGTTTATCTTCGTATACAGTGCCCTTAGAAAGAGATAACTCAGAAGAATTTTTAAAACGGGAAGCAAGGGCAAACCAGTTAGC
AGAAGAAATTGAGTCAAGTGCCCAGTACAAAGCTCGAGTGGCCCTGGAAAATGATGATAGGAGTGAGGAAGAAAAATACACAGCAGTTCA
GAGAAATTCCAGTGAACGTGAGGGGCACAGCATAAACACTAGGGAAAATAAATATATTCCTCCTGGACAAAGAAATAGAGAAGTCATATC
CTGGGGAAGTGGGAGACAGAATTCACCGCGTATGGGCCAGCCTGGATCGGGCTCCATGCCATCAAGATCCACTTCTCACACTTCAGATTT
CAACCCGAATTCTGGTTCAGACCAAAGAGTAGTTAATGGAGGTGTTCCCTGGCCATCGCCTTGCCCATCTCCTTCCTCTCGCCCACCTTC
TCGCTACCAGTCAGGTCCCAACTCTCTTCCACCTCGGGCAGCCACCCCTACACGGCCGCCCTCCAGGCCCCCCTCGCGGCCATCCAGACC
CCCGTCTCACCCCTCTGCTCATGGTTCTCCAGCTCCTGTCTCTACTATGCCTAAACGCATGTCTTCAGAAGGGCCTCCAAGGATGTCCCC
AAAGGCCCAGCGACATCCTCGAAATCACAGAGTTTCTGCTGGGAGGGGTTCCATATCCAGTGGCCTAGAATTTGTATCCCACAACCCACC
CAGTGAAGCAGCTACTCCTCCAGTAGCAAGGACCAGTCCCTCGGGGGGAACGTGGTCATCAGTGGTCAGTGGGGTTCCAAGATTATCCCC
TAAAACTCATAGACCCAGGTCTCCCAGACAGAACAGTATTGGAAATACCCCCAGTGGGCCAGTTCTTGCTTCTCCCCAAGCTGGTATTAT
TCCAACTGAAGCTGTTGCCATGCCTATTCCAGCTGCATCTCCTACGCCTGCTAGTCCTGCATCGAACAGAGCTGTTACCCCTTCTAGTGA
GGCTAAAGATTCCAGGCTTCAAGATCAGAGGCAGAACTCTCCTGCAGGGAATAAAGAAAATATTAAACCCAATGAAACATCACCTAGCTT
CTCAAAAGCTGAAAACAAAGGTATATCACCAGTTGTTTCTGAACATAGAAAACAGATTGATGATTTAAAGAAATTTAAGAATGATTTTAG
GATTAACAACATGAAGACCAAGTTTAAAGAAACAATTGAGAAGTGTGATAATCTAGAGCACAAACTAAATGATCTCCTAAAAGAAAAGCA
GTCTGTGGAAAGAAAGTGCACTCAGCTAAACACAAAAGTGGCCAAACTCACCAACGAGCTCAAAGAGGAGCAGGAAATGAACAAGTGTTT
GCGAGCCAACCAAGTCCTCCTGCAGAACAAGCTAAAAGAGGAGGAGAGGGTGCTGAAGGAGACCTGTGACCAAAAAGATCTGCAGATCAC
CGAGATCCAGGAGCAGCTGCGTGACGTCATGTTCTACCTGGAGACACAGCAGAAGATCAACCATCTGCCTGCCGAGACCCGGCAGGAAAT
CCAGGAGGGACAGATCAACATCGCCATGGCCTCGGCCTCGAGCCCTGCCTCTTCGGGGGGCAGTGGGAAGTTGCCCTCCAGGAAGGGCCG
CAGCAAGAGGGGCAAGTGACCTTCAGAGCAACAGACATCCCTGAGACTGTTCTCCCTGACACTGTGAGAGTGTGCTGGGACCTTCAGCTA
AATGTGAGGGTGGGCCCTAATAAGTACAAGTGAGGATCAAGCCACAGTTGTTTGGCTCTTTCATTTGCTAGTGTGTGATGTAGTGAATGT
AAAGGGTGCTGACTGGAGAGCTGATAGAAAGGCGCTGCGTTCGAAAAGGTCTTAAGAGTTCACTAACCTCACATTCTAATGACCATTTTG

>8416_8416_12_ATXN2-BRAP_ATXN2_chr12_111947353_ENST00000608853_BRAP_chr12_112087846_ENST00000539060_length(amino acids)=821AA_BP=664
MARPAPGCPRPACEPVYGPLTMSLKPQQQQQQQQQQQQQQQQQQQQQQQPPPAAANVRKPGGSGLLASPAAAPSPSSSSVSSSSATAPSS
VVAATSGGGRPGLGRGRNSNKGLPQSTISFDGIYANMRMVHILTSVVGSKCEVQVKNGGIYEGVFKTYSPKCDLVLDAAHEKSTESSSGP
KREEIMESILFKCSDFVVVQFKDMDSSYAKRDAFTDSAISAKVNGEHKEKDLEPWDAGELTANEELEALENDVSNGWDPNDMFRYNEENY
GVVSTYDSSLSSYTVPLERDNSEEFLKREARANQLAEEIESSAQYKARVALENDDRSEEEKYTAVQRNSSEREGHSINTRENKYIPPGQR
NREVISWGSGRQNSPRMGQPGSGSMPSRSTSHTSDFNPNSGSDQRVVNGGVPWPSPCPSPSSRPPSRYQSGPNSLPPRAATPTRPPSRPP
SRPSRPPSHPSAHGSPAPVSTMPKRMSSEGPPRMSPKAQRHPRNHRVSAGRGSISSGLEFVSHNPPSEAATPPVARTSPSGGTWSSVVSG
VPRLSPKTHRPRSPRQNSIGNTPSGPVLASPQAGIIPTEAVAMPIPAASPTPASPASNRAVTPSSEAKDSRLQDQRQNSPAGNKENIKPN
ETSPSFSKAENKGISPVVSEHRKQIDDLKKFKNDFRINNMKTKFKETIEKCDNLEHKLNDLLKEKQSVERKCTQLNTKVAKLTNELKEEQ
EMNKCLRANQVLLQNKLKEEERVLKETCDQKDLQITEIQEQLRDVMFYLETQQKINHLPAETRQEIQEGQINIAMASASSPASSGGSGKL

--------------------------------------------------------------

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Fusion Gene PPI Analysis for ATXN2-BRAP


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for ATXN2-BRAP


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for ATXN2-BRAP


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource