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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:SMURF1-AKAP9 (FusionGDB2 ID:84305)

Fusion Gene Summary for SMURF1-AKAP9

check button Fusion gene summary
Fusion gene informationFusion gene name: SMURF1-AKAP9
Fusion gene ID: 84305
HgeneTgene
Gene symbol

SMURF1

AKAP9

Gene ID

57154

10142

Gene nameSMAD specific E3 ubiquitin protein ligase 1A-kinase anchoring protein 9
Synonyms-AKAP-9|AKAP350|AKAP450|CG-NAP|HYPERION|LQT11|MU-RMS-40.16A|PPP1R45|PRKA9|YOTIAO
Cytomap

7q22.1

7q21.2

Type of geneprotein-codingprotein-coding
DescriptionE3 ubiquitin-protein ligase SMURF1E3 ubiquitin ligase SMURF1HECT-type E3 ubiquitin transferase SMURF1Smad ubiquitination regulatory factor 1Smad-specific E3 ubiquitin ligase 1hSMURF1A-kinase anchor protein 9A kinase (PRKA) anchor protein (yotiao) 9A kinase (PRKA) anchor protein 9A-kinase anchor protein 350 kDaA-kinase anchor protein 450 kDaAKAP 120-like proteinAKAP9-BRAF fusion proteincentrosome- and Golgi-localized PKN-associ
Modification date2020031320200328
UniProtAcc.

Q99996

Ensembl transtripts involved in fusion geneENST00000361125, ENST00000361368, 
ENST00000480055, 		ENST00000394564, 
ENST00000491695, ENST00000356239, 
ENST00000358100, ENST00000359028, 
Fusion gene scores* DoF score19 X 8 X 12=182411 X 17 X 7=1309
# samples 2415
** MAII scorelog2(24/1824*10)=-2.92599941855622
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(15/1309*10)=-3.12543069144936
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: SMURF1 [Title/Abstract] AND AKAP9 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointSMURF1(98741349)-AKAP9(91711836), # samples:1
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneSMURF1

GO:0000209

protein polyubiquitination

19937093

HgeneSMURF1

GO:0006511

ubiquitin-dependent protein catabolic process

10458166|12151385|19937093

HgeneSMURF1

GO:0006611

protein export from nucleus

11278251

HgeneSMURF1

GO:0016567

protein ubiquitination

11278251

HgeneSMURF1

GO:0030154

cell differentiation

10458166

HgeneSMURF1

GO:0030509

BMP signaling pathway

21572392

HgeneSMURF1

GO:0030512

negative regulation of transforming growth factor beta receptor signaling pathway

11278251|12151385

HgeneSMURF1

GO:0030514

negative regulation of BMP signaling pathway

27214554

HgeneSMURF1

GO:0030579

ubiquitin-dependent SMAD protein catabolic process

11278251|12151385

HgeneSMURF1

GO:0032801

receptor catabolic process

12151385

HgeneSMURF1

GO:0034394

protein localization to cell surface

12151385

HgeneSMURF1

GO:0043161

proteasome-mediated ubiquitin-dependent protein catabolic process

11278251

HgeneSMURF1

GO:1903861

positive regulation of dendrite extension

23999003

TgeneAKAP9

GO:0098962

regulation of postsynaptic neurotransmitter receptor activity

10390370

TgeneAKAP9

GO:1903358

regulation of Golgi organization

27666745


check buttonFusion gene breakpoints across SMURF1 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across AKAP9 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4PAADTCGA-IB-AAUS-01ASMURF1chr7

98741349

-AKAP9chr7

91711836

+


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Fusion Gene ORF analysis for SMURF1-AKAP9

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000361125ENST00000394564SMURF1chr7

98741349

-AKAP9chr7

91711836

+
5CDS-intronENST00000361125ENST00000491695SMURF1chr7

98741349

-AKAP9chr7

91711836

+
5CDS-intronENST00000361368ENST00000394564SMURF1chr7

98741349

-AKAP9chr7

91711836

+
5CDS-intronENST00000361368ENST00000491695SMURF1chr7

98741349

-AKAP9chr7

91711836

+
In-frameENST00000361125ENST00000356239SMURF1chr7

98741349

-AKAP9chr7

91711836

+
In-frameENST00000361125ENST00000358100SMURF1chr7

98741349

-AKAP9chr7

91711836

+
In-frameENST00000361125ENST00000359028SMURF1chr7

98741349

-AKAP9chr7

91711836

+
In-frameENST00000361368ENST00000356239SMURF1chr7

98741349

-AKAP9chr7

91711836

+
In-frameENST00000361368ENST00000358100SMURF1chr7

98741349

-AKAP9chr7

91711836

+
In-frameENST00000361368ENST00000359028SMURF1chr7

98741349

-AKAP9chr7

91711836

+
intron-3CDSENST00000480055ENST00000356239SMURF1chr7

98741349

-AKAP9chr7

91711836

+
intron-3CDSENST00000480055ENST00000358100SMURF1chr7

98741349

-AKAP9chr7

91711836

+
intron-3CDSENST00000480055ENST00000359028SMURF1chr7

98741349

-AKAP9chr7

91711836

+
intron-intronENST00000480055ENST00000394564SMURF1chr7

98741349

-AKAP9chr7

91711836

+
intron-intronENST00000480055ENST00000491695SMURF1chr7

98741349

-AKAP9chr7

91711836

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000361368SMURF1chr798741349-ENST00000356239AKAP9chr791711836+451329443239981188
ENST00000361368SMURF1chr798741349-ENST00000358100AKAP9chr791711836+432729443238121126
ENST00000361368SMURF1chr798741349-ENST00000359028AKAP9chr791711836+448929443239741180
ENST00000361125SMURF1chr798741349-ENST00000356239AKAP9chr791711836+459437551340791188
ENST00000361125SMURF1chr798741349-ENST00000358100AKAP9chr791711836+440837551338931126
ENST00000361125SMURF1chr798741349-ENST00000359028AKAP9chr791711836+457037551340551180

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000361368ENST00000356239SMURF1chr798741349-AKAP9chr791711836+0.0023275660.9976724
ENST00000361368ENST00000358100SMURF1chr798741349-AKAP9chr791711836+0.0023263320.9976737
ENST00000361368ENST00000359028SMURF1chr798741349-AKAP9chr791711836+0.001894870.99810517
ENST00000361125ENST00000356239SMURF1chr798741349-AKAP9chr791711836+0.0026176760.99738234
ENST00000361125ENST00000358100SMURF1chr798741349-AKAP9chr791711836+0.0025660060.99743396
ENST00000361125ENST00000359028SMURF1chr798741349-AKAP9chr791711836+0.0020663280.9979336

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Fusion Genomic Features for SMURF1-AKAP9


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
SMURF1chr798741348-AKAP9chr791711835+3.59E-091
SMURF1chr798741348-AKAP9chr791711835+3.59E-091

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for SMURF1-AKAP9


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr7:98741349/chr7:91711836)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
.AKAP9

Q99996

FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Scaffolding protein that assembles several protein kinases and phosphatases on the centrosome and Golgi apparatus. Required to maintain the integrity of the Golgi apparatus (PubMed:10202149, PubMed:15047863). Required for microtubule nucleation at the cis-side of the Golgi apparatus (PubMed:15047863, PubMed:19242490). Required for association of the centrosomes with the poles of the bipolar mitotic spindle during metaphase (PubMed:25657325). In complex with PDE4DIP isoform 13/MMG8/SMYLE, recruits CAMSAP2 to the Golgi apparatus and tethers non-centrosomal minus-end microtubules to the Golgi, an important step for polarized cell movement (PubMed:27666745, PubMed:28814570). In complex with PDE4DIP isoform 13/MMG8/SMYLE, EB1/MAPRE1 and CDK5RAP2, contributes to microtubules nucleation and extension also from the centrosome to the cell periphery (PubMed:29162697). {ECO:0000269|PubMed:10202149, ECO:0000269|PubMed:15047863, ECO:0000269|PubMed:19242490, ECO:0000269|PubMed:25657325, ECO:0000269|PubMed:27666745, ECO:0000269|PubMed:28814570, ECO:0000269|PubMed:29162697}.; FUNCTION: [Isoform 4]: Associated with the N-methyl-D-aspartate receptor and is specifically found in the neuromuscular junction (NMJ) as well as in neuronal synapses, suggesting a role in the organization of postsynaptic specializations. {ECO:0000269|PubMed:9482789}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneAKAP9chr7:98741349chr7:91711836ENST0000035623930503061_308826733908.0Coiled coilOntology_term=ECO:0000255
TgeneAKAP9chr7:98741349chr7:91711836ENST0000035623930503120_346626733908.0Coiled coilOntology_term=ECO:0000255
TgeneAKAP9chr7:98741349chr7:91711836ENST0000035623930503583_368526733908.0Coiled coilOntology_term=ECO:0000255
TgeneAKAP9chr7:98741349chr7:91711836ENST0000035810031493061_308826853858.0Coiled coilOntology_term=ECO:0000255
TgeneAKAP9chr7:98741349chr7:91711836ENST0000035810031493120_346626853858.0Coiled coilOntology_term=ECO:0000255
TgeneAKAP9chr7:98741349chr7:91711836ENST0000035810031493583_368526853858.0Coiled coilOntology_term=ECO:0000255
TgeneAKAP9chr7:98741349chr7:91711836ENST0000035902831503061_308826853912.0Coiled coilOntology_term=ECO:0000255
TgeneAKAP9chr7:98741349chr7:91711836ENST0000035902831503120_346626853912.0Coiled coilOntology_term=ECO:0000255
TgeneAKAP9chr7:98741349chr7:91711836ENST0000035902831503583_368526853912.0Coiled coilOntology_term=ECO:0000255
TgeneAKAP9chr7:98741349chr7:91711836ENST0000035623930503722_372626733908.0Compositional biasNote=Poly-Leu
TgeneAKAP9chr7:98741349chr7:91711836ENST0000035810031493722_372626853858.0Compositional biasNote=Poly-Leu
TgeneAKAP9chr7:98741349chr7:91711836ENST0000035902831503722_372626853912.0Compositional biasNote=Poly-Leu

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneSMURF1chr7:98741349chr7:91711836ENST00000361125-1191_12018758.0DomainC2
HgeneSMURF1chr7:98741349chr7:91711836ENST00000361125-119234_26718758.0DomainWW 1
HgeneSMURF1chr7:98741349chr7:91711836ENST00000361125-119306_33918758.0DomainWW 2
HgeneSMURF1chr7:98741349chr7:91711836ENST00000361125-119420_75718758.0DomainHECT
HgeneSMURF1chr7:98741349chr7:91711836ENST00000361368-1181_12018732.0DomainC2
HgeneSMURF1chr7:98741349chr7:91711836ENST00000361368-118234_26718732.0DomainWW 1
HgeneSMURF1chr7:98741349chr7:91711836ENST00000361368-118306_33918732.0DomainWW 2
HgeneSMURF1chr7:98741349chr7:91711836ENST00000361368-118420_75718732.0DomainHECT
TgeneAKAP9chr7:98741349chr7:91711836ENST0000035623930501088_117326733908.0Coiled coilOntology_term=ECO:0000255
TgeneAKAP9chr7:98741349chr7:91711836ENST0000035623930501241_126826733908.0Coiled coilOntology_term=ECO:0000255
TgeneAKAP9chr7:98741349chr7:91711836ENST0000035623930501324_138026733908.0Coiled coilOntology_term=ECO:0000255
TgeneAKAP9chr7:98741349chr7:91711836ENST0000035623930501422_144726733908.0Coiled coilOntology_term=ECO:0000255
TgeneAKAP9chr7:98741349chr7:91711836ENST000003562393050152_90226733908.0Coiled coilOntology_term=ECO:0000255
TgeneAKAP9chr7:98741349chr7:91711836ENST0000035623930501573_164726733908.0Coiled coilOntology_term=ECO:0000255
TgeneAKAP9chr7:98741349chr7:91711836ENST0000035623930501845_244326733908.0Coiled coilOntology_term=ECO:0000255
TgeneAKAP9chr7:98741349chr7:91711836ENST0000035623930502532_254926733908.0Coiled coilOntology_term=ECO:0000255
TgeneAKAP9chr7:98741349chr7:91711836ENST0000035623930502591_276426733908.0Coiled coilOntology_term=ECO:0000255
TgeneAKAP9chr7:98741349chr7:91711836ENST000003562393050932_101026733908.0Coiled coilOntology_term=ECO:0000255
TgeneAKAP9chr7:98741349chr7:91711836ENST0000035810031491088_117326853858.0Coiled coilOntology_term=ECO:0000255
TgeneAKAP9chr7:98741349chr7:91711836ENST0000035810031491241_126826853858.0Coiled coilOntology_term=ECO:0000255
TgeneAKAP9chr7:98741349chr7:91711836ENST0000035810031491324_138026853858.0Coiled coilOntology_term=ECO:0000255
TgeneAKAP9chr7:98741349chr7:91711836ENST0000035810031491422_144726853858.0Coiled coilOntology_term=ECO:0000255
TgeneAKAP9chr7:98741349chr7:91711836ENST000003581003149152_90226853858.0Coiled coilOntology_term=ECO:0000255
TgeneAKAP9chr7:98741349chr7:91711836ENST0000035810031491573_164726853858.0Coiled coilOntology_term=ECO:0000255
TgeneAKAP9chr7:98741349chr7:91711836ENST0000035810031491845_244326853858.0Coiled coilOntology_term=ECO:0000255
TgeneAKAP9chr7:98741349chr7:91711836ENST0000035810031492532_254926853858.0Coiled coilOntology_term=ECO:0000255
TgeneAKAP9chr7:98741349chr7:91711836ENST0000035810031492591_276426853858.0Coiled coilOntology_term=ECO:0000255
TgeneAKAP9chr7:98741349chr7:91711836ENST000003581003149932_101026853858.0Coiled coilOntology_term=ECO:0000255
TgeneAKAP9chr7:98741349chr7:91711836ENST0000035902831501088_117326853912.0Coiled coilOntology_term=ECO:0000255
TgeneAKAP9chr7:98741349chr7:91711836ENST0000035902831501241_126826853912.0Coiled coilOntology_term=ECO:0000255
TgeneAKAP9chr7:98741349chr7:91711836ENST0000035902831501324_138026853912.0Coiled coilOntology_term=ECO:0000255
TgeneAKAP9chr7:98741349chr7:91711836ENST0000035902831501422_144726853912.0Coiled coilOntology_term=ECO:0000255
TgeneAKAP9chr7:98741349chr7:91711836ENST000003590283150152_90226853912.0Coiled coilOntology_term=ECO:0000255
TgeneAKAP9chr7:98741349chr7:91711836ENST0000035902831501573_164726853912.0Coiled coilOntology_term=ECO:0000255
TgeneAKAP9chr7:98741349chr7:91711836ENST0000035902831501845_244326853912.0Coiled coilOntology_term=ECO:0000255
TgeneAKAP9chr7:98741349chr7:91711836ENST0000035902831502532_254926853912.0Coiled coilOntology_term=ECO:0000255
TgeneAKAP9chr7:98741349chr7:91711836ENST0000035902831502591_276426853912.0Coiled coilOntology_term=ECO:0000255
TgeneAKAP9chr7:98741349chr7:91711836ENST000003590283150932_101026853912.0Coiled coilOntology_term=ECO:0000255
TgeneAKAP9chr7:98741349chr7:91711836ENST0000035623930501834_276026733908.0Compositional biasNote=Glu-rich
TgeneAKAP9chr7:98741349chr7:91711836ENST000003562393050191_28026733908.0Compositional biasNote=Gln-rich
TgeneAKAP9chr7:98741349chr7:91711836ENST000003562393050309_99826733908.0Compositional biasNote=Glu-rich
TgeneAKAP9chr7:98741349chr7:91711836ENST0000035810031491834_276026853858.0Compositional biasNote=Glu-rich
TgeneAKAP9chr7:98741349chr7:91711836ENST000003581003149191_28026853858.0Compositional biasNote=Gln-rich
TgeneAKAP9chr7:98741349chr7:91711836ENST000003581003149309_99826853858.0Compositional biasNote=Glu-rich
TgeneAKAP9chr7:98741349chr7:91711836ENST0000035902831501834_276026853912.0Compositional biasNote=Glu-rich
TgeneAKAP9chr7:98741349chr7:91711836ENST000003590283150191_28026853912.0Compositional biasNote=Gln-rich
TgeneAKAP9chr7:98741349chr7:91711836ENST000003590283150309_99826853912.0Compositional biasNote=Glu-rich
TgeneAKAP9chr7:98741349chr7:91711836ENST0000035623930502542_255526733908.0RegionNote=PKA-RII subunit binding domain
TgeneAKAP9chr7:98741349chr7:91711836ENST0000035810031492542_255526853858.0RegionNote=PKA-RII subunit binding domain
TgeneAKAP9chr7:98741349chr7:91711836ENST0000035902831502542_255526853912.0RegionNote=PKA-RII subunit binding domain


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Fusion Gene Sequence for SMURF1-AKAP9


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>84305_84305_1_SMURF1-AKAP9_SMURF1_chr7_98741349_ENST00000361125_AKAP9_chr7_91711836_ENST00000356239_length(transcript)=4594nt_BP=375nt
GGCAGCGGCGGAAGCGGCGAGGGCGGCGGGCGTCCGGCTCTGAGGTGGTGGAGGCGGCGGAGGCGGCGGCGGAGGCGGCGGCGGCTCGGG
ACTGGGCTCGGCTGGAAGCAGCGAGGGTCAGAGCGCCGCAGCAAGCGCCGATCTCCCGGCTCGACCATCCGCCTGCCGCCCGGACGCCTG
GGCCGCGGAGTTTGTGTCCCGGCTCGGACCCCGGCGCCCAGCCCGGAGCCGTAACCTTGAGGCGGCGGCGGCGGGGCCGGGCCGGGCCGG
GCTGGGGGGCGGTGGCGCTGGATCCGCGGCTGCCCGATCGTTGGCGGGAGATGTCGAACCCCGGGACACGCAGGAACGGCTCCAGCATCA
AGATCCGTCTGACAGACAACTACTGAGCTATTTCATAGCAATGAAGAAAGTGGATTTTTTAATGAACTCGAGGCTCTTAGAGCTGAATCA
GTGGCTACCAAAGCAGAACTTGCCAGTTATAAAGAAAAGGCTGAAAAACTTCAAGAAGAGCTTTTGGTAAAAGAAACAAATATGACATCT
CTTCAGAAAGACTTAAGCCAAGTTAGGGATCACCTCGCAGAGGCAAAAGAGAAATTGTCCATTTTAGAAAAAGAAGATGAGACTGAGGTA
CAAGAAAGCAAAAAGGCCTGCATGTTTGAGCCACTTCCTATAAAACTGAGTAAGAGCATTGCATCCCAGACAGATGGGACTCTGAAGATC
AGTAGCAGCAATCAGACTCCACAAATTCTTGTTAAAAATGCAGGAATACAAATTAATTTACAGAGTGAATGTTCCTCAGAAGAAGTTACT
GAAATAATCAGTCAGTTTACTGAAAAAATTGAGAAGATGCAAGAACTACATGCTGCTGAAATTTTGGACATGGAATCCAGACATATTTCA
GAAACTGAAACCTTAAAGAGGGAACACTATGTTGCCGTTCAGTTACTGAAAGAGGAATGTGGTACCTTGAAGGCAGTGATACAGTGTCTG
AGAAGTAAAGAGGGATCCTCAATTCCTGAGCTAGCACATTCTGATGCTTACCAGACTAGAGAAATATGCTCCAGTGATTCTGGATCAGAC
TGGGGTCAGGGAATTTATCTTACACACAGTCAGGGATTTGACATAGCATCAGAAGGCCGAGGAGAAGAAAGTGAAAGTGCAACAGATTCC
TTTCCAAAGAAAATAAAGGGATTACTGAGAGCTGTCCATAATGAAGGCATGCAGGTGCTTTCTCTCACTGAGTCTCCCTATAGTGATGGA
GAGGACCATTCTATTCAGCAGGTTTCAGAACCTTGGCTAGAAGAGAGAAAAGCTTACATCAATACAATCTCATCTCTAAAGGATTTAATT
ACAAAGATGCAACTGCAAAGAGAAGCCGAGGTTTATGATAGTTCTCAATCTCATGAGAGCTTCTCAGACTGGCGAGGTGAACTACTGCTT
GCCCTTCAACAAGTTTTCTTAGAAGAGCGTAGTGTTTTACTAGCAGCATTTCGGACGGAGCTGACAGCTCTAGGTACTACAGATGCAGTT
GGTTTACTAAACTGTTTGGAACAGAGAATACAAGAACAGGGTGTTGAATATCAAGCAGCTATGGAATGCCTCCAGAAAGCAGATAGAAGG
AGTTTGTTATCTGAAATTCAGGCACTGCATGCACAAATGAATGGTAGGAAAATTACTCTGAAAAGAGAACAAGAGAGTGAGAAACCAAGC
CAAGAACTCTTGGAATATAATATACAGCAGAAGCAGTCTCAAATGCTGGAGATGCAAGTGGAGCTCAGCAGTATGAAAGACAGAGCAACG
GAACTGCAGGAGCAGCTGAGTTCTGAGAAAATGGTGGTTGCTGAACTGAAGAGTGAGCTTGCACAAACTAAATTGGAACTAGAAACAACA
CTCAAGGCACAGCATAAACACCTAAAAGAATTGGAGGCTTTCAGGTTGGAAGTTAAAGATAAGACAGATGAAGTACATTTGCTTAATGAC
ACATTAGCAAGTGAACAGAAAAAATCAAGAGAGCTCCAGTGGGCTTTGGAGAAAGAGAAAGCCAAGTTGGGACGCAGTGAAGAACGGGAT
AAAGAAGAACTTGAGGATCTGAAGTTTTCACTTGAGAGTCAGAAACAAAGGAATCTTCAGCTAAATCTACTTTTGGAACAACAGAAACAA
CTACTGAACGAATCCCAGCAAAAAATAGAATCACAGAGAATGCTATATGATGCCCAGTTGTCAGAAGAACAAGGTCGAAACTTAGAGCTT
CAGGTACTTCTTGAATCTGAGAAAGTTCGAATTCGGGAAATGAGTAGTACCCTAGATAGGGAGCGGGAATTGCACGCACAGCTGCAGAGC
AGTGATGGTACTGGACAGTCTCGGCCACCCTTGCCCTCAGAGGACCTACTGAAAGAGCTGCAGAAACAGCTAGAGGAAAAACACAGTCGC
ATAGTAGAATTGTTAAATGAGACTGAAAAATATAAACTGGATTCTTTGCAAACACGACAGCAAATGGAAAAAGATAGGCAGGTTCACAGG
AAAACACTGCAGACAGAACAGGAGGCCAACACTGAGGGACAGAAAAAAATGCATGAGCTCCAGTCCAAAGTGGAAGATCTTCAGCGCCAG
CTGGAAGAGAAAAGACAACAAGTTTATAAGTTAGACCTTGAAGGACAGCGACTACAAGGAATCATGCAGGAATTCCAGAAGCAAGAACTA
GAACGAGAAGAAAAACGAGAAAGTAGAAGAATTCTGTATCAGAACCTTAATGAGCCAACCACGTGGAGCTTAACCAGTGATAGAACTAGA
AATTGGGTTCTTCAACAGAAAATAGAAGGAGAAACAAAAGAATCAAACTACGCTAAATTGATTGAAATGAATGGAGGAGGAACCGGCTGT
AATCATGAATTAGAAATGATCAGACAAAAGCTTCAATGTGTAGCTTCAAAACTACAGGTTCTACCCCAGAAAGCCTCTGAGAGACTACAG
TTTGAAACAGCAGATGATGAAGATTTCATTTGGGTTCAGGAAAATATTGATGAAATTATTTTACAACTACAGAAATTAACTGGCCAGCAA
GGTGAAGAGCCCAGCTTGGTGTCCCCAAGTACTTCTTGTGGCTCATTGACTGAAAGACTACTGAGACAAAATGCTGAGCTGACAGGGCAT
ATCAGTCAACTGACTGAAGAGAAGAATGACTTAAGGAACATGGTTATGAAGCTGGAAGAGCAGATCAGGTGGTATCGACAGACAGGAGCT
GGTAGAGATAATTCTTCCAGGTTTTCATTGAATGGTGGTGCCAACATTGAAGCCATCATTGCCTCTGAAAAAGAAGTATGGAACAGAGAA
AAATTGACTCTCCAGAAATCTTTGAAAAGGGCAGAGGCTGAAGTATACAAACTGAAAGCTGAACTAAGAAATGACTCTTTACTTCAAACT
CTGAGCCCTGATTCTGAACATGTCACTTTAAAGAGAATTTATGGTAAATACTTGAGGGCAGAAAGTTTTCGAAAGGCTCTCATTTACCAG
AAGAAATACCTGCTGCTGTTACTGGGTGGGTTCCAGGAATGTGAAGATGCCACCTTGGCCCTGCTTGCCCGGATGGGGGGGCAGCCAGCT
TTCACGGATCTAGAGGTGATCACCAATCGCCCAAAGGGCTTCACCAGGTTTCGGTCGGCCGTCAGAGTATCCATTGCAATTTCCAGAATG
AAATTTTTGGTTCGACGGTGGCATCGAGTCACAGGTTCTGTTTCCATCAATATTAACAGAGATGGCTTTGGACTGAATCAAGGTGCAGAA
AAGACTGACTCATTTTATCATTCTTCTGGTGGGCTGGAGTTATATGGAGAACCAAGACATACTACGTATCGCTCAAGATCAGATCTGGAC
TATATTAGGTCCCCTTTACCATTTCAGAATAGGTACCCAGGCACTCCAGCTGATTTCAATCCTGGTTCTTTAGCATGTTCTCAGCTTCAG
AATTACGATCCTGACAGAGCCCTAACAGATTATATCACTCGGCTAGAGGCACTGCAAAGACGACTTGGAACTATACAGTCAGGTTCAACT
ACTCAATTTCATGCTGGCATGAGAAGATAATCCTTTGAAACATCATTAATTGAAGTGATTTTAAATAGATTTCCTTTTGTAAATCAATGG
TTCTTTTGTGCTTTTGTATTGTGAATATTCAATGGGACCAATATGAACACAGCTTATGATTGTATACAAATCCCTTGCCAGCACATGAAA
ACAAACTGGAATTTGTATATATAAGCATTGTGTATGTATTCATGCACAATAATTATTGAATTACCTGTATATTTGTGGAATGCTAATTTA
AAACATTAAATTATAAACCTTGTGTATTTATCAAATGGGTGAAAAGATTAAACTTTTACGCATTACAATACTGCTGAATGTGTAGCTCGA
GGTGTCCTGCACTTTTCTTATAAGGCTACTGAAGTTACATGTTTTGCCTAATATATTCTACTGGTGATGAAGACAGATAATATCACTTGT
AGAGACCTATTTTTGTATAATGGTAGAAGTTTTGAATTTTATGGGGTATTTTGTCAAGTACTGAAATAAAAATGACTTCACCATTTTCAC

>84305_84305_1_SMURF1-AKAP9_SMURF1_chr7_98741349_ENST00000361125_AKAP9_chr7_91711836_ENST00000356239_length(amino acids)=1188AA_BP=
MVKETNMTSLQKDLSQVRDHLAEAKEKLSILEKEDETEVQESKKACMFEPLPIKLSKSIASQTDGTLKISSSNQTPQILVKNAGIQINLQ
SECSSEEVTEIISQFTEKIEKMQELHAAEILDMESRHISETETLKREHYVAVQLLKEECGTLKAVIQCLRSKEGSSIPELAHSDAYQTRE
ICSSDSGSDWGQGIYLTHSQGFDIASEGRGEESESATDSFPKKIKGLLRAVHNEGMQVLSLTESPYSDGEDHSIQQVSEPWLEERKAYIN
TISSLKDLITKMQLQREAEVYDSSQSHESFSDWRGELLLALQQVFLEERSVLLAAFRTELTALGTTDAVGLLNCLEQRIQEQGVEYQAAM
ECLQKADRRSLLSEIQALHAQMNGRKITLKREQESEKPSQELLEYNIQQKQSQMLEMQVELSSMKDRATELQEQLSSEKMVVAELKSELA
QTKLELETTLKAQHKHLKELEAFRLEVKDKTDEVHLLNDTLASEQKKSRELQWALEKEKAKLGRSEERDKEELEDLKFSLESQKQRNLQL
NLLLEQQKQLLNESQQKIESQRMLYDAQLSEEQGRNLELQVLLESEKVRIREMSSTLDRERELHAQLQSSDGTGQSRPPLPSEDLLKELQ
KQLEEKHSRIVELLNETEKYKLDSLQTRQQMEKDRQVHRKTLQTEQEANTEGQKKMHELQSKVEDLQRQLEEKRQQVYKLDLEGQRLQGI
MQEFQKQELEREEKRESRRILYQNLNEPTTWSLTSDRTRNWVLQQKIEGETKESNYAKLIEMNGGGTGCNHELEMIRQKLQCVASKLQVL
PQKASERLQFETADDEDFIWVQENIDEIILQLQKLTGQQGEEPSLVSPSTSCGSLTERLLRQNAELTGHISQLTEEKNDLRNMVMKLEEQ
IRWYRQTGAGRDNSSRFSLNGGANIEAIIASEKEVWNREKLTLQKSLKRAEAEVYKLKAELRNDSLLQTLSPDSEHVTLKRIYGKYLRAE
SFRKALIYQKKYLLLLLGGFQECEDATLALLARMGGQPAFTDLEVITNRPKGFTRFRSAVRVSIAISRMKFLVRRWHRVTGSVSININRD
GFGLNQGAEKTDSFYHSSGGLELYGEPRHTTYRSRSDLDYIRSPLPFQNRYPGTPADFNPGSLACSQLQNYDPDRALTDYITRLEALQRR

--------------------------------------------------------------
>84305_84305_2_SMURF1-AKAP9_SMURF1_chr7_98741349_ENST00000361125_AKAP9_chr7_91711836_ENST00000358100_length(transcript)=4408nt_BP=375nt
GGCAGCGGCGGAAGCGGCGAGGGCGGCGGGCGTCCGGCTCTGAGGTGGTGGAGGCGGCGGAGGCGGCGGCGGAGGCGGCGGCGGCTCGGG
ACTGGGCTCGGCTGGAAGCAGCGAGGGTCAGAGCGCCGCAGCAAGCGCCGATCTCCCGGCTCGACCATCCGCCTGCCGCCCGGACGCCTG
GGCCGCGGAGTTTGTGTCCCGGCTCGGACCCCGGCGCCCAGCCCGGAGCCGTAACCTTGAGGCGGCGGCGGCGGGGCCGGGCCGGGCCGG
GCTGGGGGGCGGTGGCGCTGGATCCGCGGCTGCCCGATCGTTGGCGGGAGATGTCGAACCCCGGGACACGCAGGAACGGCTCCAGCATCA
AGATCCGTCTGACAGACAACTACTGAGCTATTTCATAGCAATGAAGAAAGTGGATTTTTTAATGAACTCGAGGCTCTTAGAGCTGAATCA
GTGGCTACCAAAGCAGAACTTGCCAGTTATAAAGAAAAGGCTGAAAAACTTCAAGAAGAGCTTTTGGTAAAAGAAACAAATATGACATCT
CTTCAGAAAGACTTAAGCCAAGTTAGGGATCACCTCGCAGAGGCAAAAGAGAAATTGTCCATTTTAGAAAAAGAAGATGAGACTGAGGTA
CAAGAAAGCAAAAAGGCCTGCATGTTTGAGCCACTTCCTATAAAACTGAGTAAGAGCATTGCATCCCAGACAGATGGGACTCTGAAGATC
AGTAGCAGCAATCAGACTCCACAAATTCTTGTTAAAAATGCAGGAATACAAATTAATTTACAGAGTGAATGTTCCTCAGAAGAAGTTACT
GAAATAATCAGTCAGTTTACTGAAAAAATTGAGAAGATGCAAGAACTACATGCTGCTGAAATTTTGGACATGGAATCCAGACATATTTCA
GAAACTGAAACCTTAAAGAGGGAACACTATGTTGCCGTTCAGTTACTGAAAGAGGAATGTGGTACCTTGAAGGCAGTGATACAGTGTCTG
AGAAGTAAAGAGGGATTACTGAGAGCTGTCCATAATGAAGGCATGCAGGTGCTTTCTCTCACTGAGTCTCCCTATAGTGATGGAGAGGAC
CATTCTATTCAGCAGGTTTCAGAACCTTGGCTAGAAGAGAGAAAAGCTTACATCAATACAATCTCATCTCTAAAGGATTTAATTACAAAG
ATGCAACTGCAAAGAGAAGCCGAGGTTTATGATAGTTCTCAATCTCATGAGAGCTTCTCAGACTGGCGAGGTGAACTACTGCTTGCCCTT
CAACAAGTTTTCTTAGAAGAGCGTAGTGTTTTACTAGCAGCATTTCGGACGGAGCTGACAGCTCTAGGTACTACAGATGCAGTTGGTTTA
CTAAACTGTTTGGAACAGAGAATACAAGAACAGGGTGTTGAATATCAAGCAGCTATGGAATGCCTCCAGAAAGCAGATAGAAGGAGTTTG
TTATCTGAAATTCAGGCACTGCATGCACAAATGAATGGTAGGAAAATTACTCTGAAAAGAGAACAAGAGAGTGAGAAACCAAGCCAAGAA
CTCTTGGAATATAATATACAGCAGAAGCAGTCTCAAATGCTGGAGATGCAAGTGGAGCTCAGCAGTATGAAAGACAGAGCAACGGAACTG
CAGGAGCAGCTGAGTTCTGAGAAAATGGTGGTTGCTGAACTGAAGAGTGAGCTTGCACAAACTAAATTGGAACTAGAAACAACACTCAAG
GCACAGCATAAACACCTAAAAGAATTGGAGGCTTTCAGGTTGGAAGTTAAAGATAAGACAGATGAAGTACATTTGCTTAATGACACATTA
GCAAGTGAACAGAAAAAATCAAGAGAGCTCCAGTGGGCTTTGGAGAAAGAGAAAGCCAAGTTGGGACGCAGTGAAGAACGGGATAAAGAA
GAACTTGAGGATCTGAAGTTTTCACTTGAGAGTCAGAAACAAAGGAATCTTCAGCTAAATCTACTTTTGGAACAACAGAAACAACTACTG
AACGAATCCCAGCAAAAAATAGAATCACAGAGAATGCTATATGATGCCCAGTTGTCAGAAGAACAAGGTCGAAACTTAGAGCTTCAGGTA
CTTCTTGAATCTGAGAAAGTTCGAATTCGGGAAATGAGTAGTACCCTAGATAGGGAGCGGGAATTGCACGCACAGCTGCAGAGCAGTGAT
GGTACTGGACAGTCTCGGCCACCCTTGCCCTCAGAGGACCTACTGAAAGAGCTGCAGAAACAGCTAGAGGAAAAACACAGTCGCATAGTA
GAATTGTTAAATGAGACTGAAAAATATAAACTGGATTCTTTGCAAACACGACAGCAAATGGAAAAAGATAGGCAGGTTCACAGGAAAACA
CTGCAGACAGAACAGGAGGCCAACACTGAGGGACAGAAAAAAATGCATGAGCTCCAGTCCAAAGTGGAAGATCTTCAGCGCCAGCTGGAA
GAGAAAAGACAACAAGTTTATAAGTTAGACCTTGAAGGACAGCGACTACAAGGAATCATGCAGGAATTCCAGAAGCAAGAACTAGAACGA
GAAGAAAAACGAGAAAGTAGAAGAATTCTGTATCAGAACCTTAATGAGCCAACCACGTGGAGCTTAACCAGTGATAGAACTAGAAATTGG
GTTCTTCAACAGAAAATAGAAGGAGAAACAAAAGAATCAAACTACGCTAAATTGATTGAAATGAATGGAGGAGGAACCGGCTGTAATCAT
GAATTAGAAATGATCAGACAAAAGCTTCAATGTGTAGCTTCAAAACTACAGGTTCTACCCCAGAAAGCCTCTGAGAGACTACAGTTTGAA
ACAGCAGATGATGAAGATTTCATTTGGGTTCAGGAAAATATTGATGAAATTATTTTACAACTACAGAAATTAACTGGCCAGCAAGGTGAA
GAGCCCAGCTTGGTGTCCCCAAGTACTTCTTGTGGCTCATTGACTGAAAGACTACTGAGACAAAATGCTGAGCTGACAGGGCATATCAGT
CAACTGACTGAAGAGAAGAATGACTTAAGGAACATGGTTATGAAGCTGGAAGAGCAGATCAGGTGGTATCGACAGACAGGAGCTGGTAGA
GATAATTCTTCCAGGTTTTCATTGAATGGTGGTGCCAACATTGAAGCCATCATTGCCTCTGAAAAAGAAGTATGGAACAGAGAAAAATTG
ACTCTCCAGAAATCTTTGAAAAGGGCAGAGGCTGAAGTATACAAACTGAAAGCTGAACTAAGAAATGACTCTTTACTTCAAACTCTGAGC
CCTGATTCTGAACATGTCACTTTAAAGAGAATTTATGGTAAATACTTGAGGGCAGAAAGTTTTCGAAAGGCTCTCATTTACCAGAAGAAA
TACCTGCTGCTGTTACTGGGTGGGTTCCAGGAATGTGAAGATGCCACCTTGGCCCTGCTTGCCCGGATGGGGGGGCAGCCAGCTTTCACG
GATCTAGAGGTGATCACCAATCGCCCAAAGGGCTTCACCAGGTTTCGGTCGGCCGTCAGAGTATCCATTGCAATTTCCAGAATGAAATTT
TTGGTTCGACGGTGGCATCGAGTCACAGGTTCTGTTTCCATCAATATTAACAGAGATGGCTTTGGACTGAATCAAGGTGCAGAAAAGACT
GACTCATTTTATCATTCTTCTGGTGGGCTGGAGTTATATGGAGAACCAAGACATACTACGTATCGCTCAAGATCAGATCTGGACTATATT
AGGTCCCCTTTACCATTTCAGAATAGGTACCCAGGCACTCCAGCTGATTTCAATCCTGGTTCTTTAGCATGTTCTCAGCTTCAGAATTAC
GATCCTGACAGAGCCCTAACAGATTATATCACTCGGCTAGAGGCACTGCAAAGACGACTTGGAACTATACAGTCAGGTTCAACTACTCAA
TTTCATGCTGGCATGAGAAGATAATCCTTTGAAACATCATTAATTGAAGTGATTTTAAATAGATTTCCTTTTGTAAATCAATGGTTCTTT
TGTGCTTTTGTATTGTGAATATTCAATGGGACCAATATGAACACAGCTTATGATTGTATACAAATCCCTTGCCAGCACATGAAAACAAAC
TGGAATTTGTATATATAAGCATTGTGTATGTATTCATGCACAATAATTATTGAATTACCTGTATATTTGTGGAATGCTAATTTAAAACAT
TAAATTATAAACCTTGTGTATTTATCAAATGGGTGAAAAGATTAAACTTTTACGCATTACAATACTGCTGAATGTGTAGCTCGAGGTGTC
CTGCACTTTTCTTATAAGGCTACTGAAGTTACATGTTTTGCCTAATATATTCTACTGGTGATGAAGACAGATAATATCACTTGTAGAGAC

>84305_84305_2_SMURF1-AKAP9_SMURF1_chr7_98741349_ENST00000361125_AKAP9_chr7_91711836_ENST00000358100_length(amino acids)=1126AA_BP=
MVKETNMTSLQKDLSQVRDHLAEAKEKLSILEKEDETEVQESKKACMFEPLPIKLSKSIASQTDGTLKISSSNQTPQILVKNAGIQINLQ
SECSSEEVTEIISQFTEKIEKMQELHAAEILDMESRHISETETLKREHYVAVQLLKEECGTLKAVIQCLRSKEGLLRAVHNEGMQVLSLT
ESPYSDGEDHSIQQVSEPWLEERKAYINTISSLKDLITKMQLQREAEVYDSSQSHESFSDWRGELLLALQQVFLEERSVLLAAFRTELTA
LGTTDAVGLLNCLEQRIQEQGVEYQAAMECLQKADRRSLLSEIQALHAQMNGRKITLKREQESEKPSQELLEYNIQQKQSQMLEMQVELS
SMKDRATELQEQLSSEKMVVAELKSELAQTKLELETTLKAQHKHLKELEAFRLEVKDKTDEVHLLNDTLASEQKKSRELQWALEKEKAKL
GRSEERDKEELEDLKFSLESQKQRNLQLNLLLEQQKQLLNESQQKIESQRMLYDAQLSEEQGRNLELQVLLESEKVRIREMSSTLDRERE
LHAQLQSSDGTGQSRPPLPSEDLLKELQKQLEEKHSRIVELLNETEKYKLDSLQTRQQMEKDRQVHRKTLQTEQEANTEGQKKMHELQSK
VEDLQRQLEEKRQQVYKLDLEGQRLQGIMQEFQKQELEREEKRESRRILYQNLNEPTTWSLTSDRTRNWVLQQKIEGETKESNYAKLIEM
NGGGTGCNHELEMIRQKLQCVASKLQVLPQKASERLQFETADDEDFIWVQENIDEIILQLQKLTGQQGEEPSLVSPSTSCGSLTERLLRQ
NAELTGHISQLTEEKNDLRNMVMKLEEQIRWYRQTGAGRDNSSRFSLNGGANIEAIIASEKEVWNREKLTLQKSLKRAEAEVYKLKAELR
NDSLLQTLSPDSEHVTLKRIYGKYLRAESFRKALIYQKKYLLLLLGGFQECEDATLALLARMGGQPAFTDLEVITNRPKGFTRFRSAVRV
SIAISRMKFLVRRWHRVTGSVSININRDGFGLNQGAEKTDSFYHSSGGLELYGEPRHTTYRSRSDLDYIRSPLPFQNRYPGTPADFNPGS

--------------------------------------------------------------
>84305_84305_3_SMURF1-AKAP9_SMURF1_chr7_98741349_ENST00000361125_AKAP9_chr7_91711836_ENST00000359028_length(transcript)=4570nt_BP=375nt
GGCAGCGGCGGAAGCGGCGAGGGCGGCGGGCGTCCGGCTCTGAGGTGGTGGAGGCGGCGGAGGCGGCGGCGGAGGCGGCGGCGGCTCGGG
ACTGGGCTCGGCTGGAAGCAGCGAGGGTCAGAGCGCCGCAGCAAGCGCCGATCTCCCGGCTCGACCATCCGCCTGCCGCCCGGACGCCTG
GGCCGCGGAGTTTGTGTCCCGGCTCGGACCCCGGCGCCCAGCCCGGAGCCGTAACCTTGAGGCGGCGGCGGCGGGGCCGGGCCGGGCCGG
GCTGGGGGGCGGTGGCGCTGGATCCGCGGCTGCCCGATCGTTGGCGGGAGATGTCGAACCCCGGGACACGCAGGAACGGCTCCAGCATCA
AGATCCGTCTGACAGACAACTACTGAGCTATTTCATAGCAATGAAGAAAGTGGATTTTTTAATGAACTCGAGGCTCTTAGAGCTGAATCA
GTGGCTACCAAAGCAGAACTTGCCAGTTATAAAGAAAAGGCTGAAAAACTTCAAGAAGAGCTTTTGGTAAAAGAAACAAATATGACATCT
CTTCAGAAAGACTTAAGCCAAGTTAGGGATCACCTCGCAGAGGCAAAAGAGAAATTGTCCATTTTAGAAAAAGAAGATGAGACTGAGGTA
CAAGAAAGCAAAAAGGCCTGCATGTTTGAGCCACTTCCTATAAAACTGAGTAAGAGCATTGCATCCCAGACAGATGGGACTCTGAAGATC
AGTAGCAGCAATCAGACTCCACAAATTCTTGTTAAAAATGCAGGAATACAAATTAATTTACAGAGTGAATGTTCCTCAGAAGAAGTTACT
GAAATAATCAGTCAGTTTACTGAAAAAATTGAGAAGATGCAAGAACTACATGCTGCTGAAATTTTGGACATGGAATCCAGACATATTTCA
GAAACTGAAACCTTAAAGAGGGAACACTATGTTGCCGTTCAGTTACTGAAAGAGGAATGTGGTACCTTGAAGGCAGTGATACAGTGTCTG
AGAAGTAAAGAGGTATTTGGTTTTTATAATATGTGTTTTTCAACATTGTGTGATTCTGGATCAGACTGGGGTCAGGGAATTTATCTTACA
CACAGTCAGGGATTTGACATAGCATCAGAAGGCCGAGGAGAAGAAAGTGAAAGTGCAACAGATTCCTTTCCAAAGAAAATAAAGGGATTA
CTGAGAGCTGTCCATAATGAAGGCATGCAGGTGCTTTCTCTCACTGAGTCTCCCTATAGTGATGGAGAGGACCATTCTATTCAGCAGGTT
TCAGAACCTTGGCTAGAAGAGAGAAAAGCTTACATCAATACAATCTCATCTCTAAAGGATTTAATTACAAAGATGCAACTGCAAAGAGAA
GCCGAGGTTTATGATAGTTCTCAATCTCATGAGAGCTTCTCAGACTGGCGAGGTGAACTACTGCTTGCCCTTCAACAAGTTTTCTTAGAA
GAGCGTAGTGTTTTACTAGCAGCATTTCGGACGGAGCTGACAGCTCTAGGTACTACAGATGCAGTTGGTTTACTAAACTGTTTGGAACAG
AGAATACAAGAACAGGGTGTTGAATATCAAGCAGCTATGGAATGCCTCCAGAAAGCAGATAGAAGGAGTTTGTTATCTGAAATTCAGGCA
CTGCATGCACAAATGAATGGTAGGAAAATTACTCTGAAAAGAGAACAAGAGAGTGAGAAACCAAGCCAAGAACTCTTGGAATATAATATA
CAGCAGAAGCAGTCTCAAATGCTGGAGATGCAAGTGGAGCTCAGCAGTATGAAAGACAGAGCAACGGAACTGCAGGAGCAGCTGAGTTCT
GAGAAAATGGTGGTTGCTGAACTGAAGAGTGAGCTTGCACAAACTAAATTGGAACTAGAAACAACACTCAAGGCACAGCATAAACACCTA
AAAGAATTGGAGGCTTTCAGGTTGGAAGTTAAAGATAAGACAGATGAAGTACATTTGCTTAATGACACATTAGCAAGTGAACAGAAAAAA
TCAAGAGAGCTCCAGTGGGCTTTGGAGAAAGAGAAAGCCAAGTTGGGACGCAGTGAAGAACGGGATAAAGAAGAACTTGAGGATCTGAAG
TTTTCACTTGAGAGTCAGAAACAAAGGAATCTTCAGCTAAATCTACTTTTGGAACAACAGAAACAACTACTGAACGAATCCCAGCAAAAA
ATAGAATCACAGAGAATGCTATATGATGCCCAGTTGTCAGAAGAACAAGGTCGAAACTTAGAGCTTCAGGTACTTCTTGAATCTGAGAAA
GTTCGAATTCGGGAAATGAGTAGTACCCTAGATAGGGAGCGGGAATTGCACGCACAGCTGCAGAGCAGTGATGGTACTGGACAGTCTCGG
CCACCCTTGCCCTCAGAGGACCTACTGAAAGAGCTGCAGAAACAGCTAGAGGAAAAACACAGTCGCATAGTAGAATTGTTAAATGAGACT
GAAAAATATAAACTGGATTCTTTGCAAACACGACAGCAAATGGAAAAAGATAGGCAGGTTCACAGGAAAACACTGCAGACAGAACAGGAG
GCCAACACTGAGGGACAGAAAAAAATGCATGAGCTCCAGTCCAAAGTGGAAGATCTTCAGCGCCAGCTGGAAGAGAAAAGACAACAAGTT
TATAAGTTAGACCTTGAAGGACAGCGACTACAAGGAATCATGCAGGAATTCCAGAAGCAAGAACTAGAACGAGAAGAAAAACGAGAAAGT
AGAAGAATTCTGTATCAGAACCTTAATGAGCCAACCACGTGGAGCTTAACCAGTGATAGAACTAGAAATTGGGTTCTTCAACAGAAAATA
GAAGGAGAAACAAAAGAATCAAACTACGCTAAATTGATTGAAATGAATGGAGGAGGAACCGGCTGTAATCATGAATTAGAAATGATCAGA
CAAAAGCTTCAATGTGTAGCTTCAAAACTACAGGTTCTACCCCAGAAAGCCTCTGAGAGACTACAGTTTGAAACAGCAGATGATGAAGAT
TTCATTTGGGTTCAGGAAAATATTGATGAAATTATTTTACAACTACAGAAATTAACTGGCCAGCAAGGTGAAGAGCCCAGCTTGGTGTCC
CCAAGTACTTCTTGTGGCTCATTGACTGAAAGACTACTGAGACAAAATGCTGAGCTGACAGGGCATATCAGTCAACTGACTGAAGAGAAG
AATGACTTAAGGAACATGGTTATGAAGCTGGAAGAGCAGATCAGGTGGTATCGACAGACAGGAGCTGGTAGAGATAATTCTTCCAGGTTT
TCATTGAATGGTGGTGCCAACATTGAAGCCATCATTGCCTCTGAAAAAGAAGTATGGAACAGAGAAAAATTGACTCTCCAGAAATCTTTG
AAAAGGGCAGAGGCTGAAGTATACAAACTGAAAGCTGAACTAAGAAATGACTCTTTACTTCAAACTCTGAGCCCTGATTCTGAACATGTC
ACTTTAAAGAGAATTTATGGTAAATACTTGAGGGCAGAAAGTTTTCGAAAGGCTCTCATTTACCAGAAGAAATACCTGCTGCTGTTACTG
GGTGGGTTCCAGGAATGTGAAGATGCCACCTTGGCCCTGCTTGCCCGGATGGGGGGGCAGCCAGCTTTCACGGATCTAGAGGTGATCACC
AATCGCCCAAAGGGCTTCACCAGGTTTCGGTCGGCCGTCAGAGTATCCATTGCAATTTCCAGAATGAAATTTTTGGTTCGACGGTGGCAT
CGAGTCACAGGTTCTGTTTCCATCAATATTAACAGAGATGGCTTTGGACTGAATCAAGGTGCAGAAAAGACTGACTCATTTTATCATTCT
TCTGGTGGGCTGGAGTTATATGGAGAACCAAGACATACTACGTATCGCTCAAGATCAGATCTGGACTATATTAGGTCCCCTTTACCATTT
CAGAATAGGTACCCAGGCACTCCAGCTGATTTCAATCCTGGTTCTTTAGCATGTTCTCAGCTTCAGAATTACGATCCTGACAGAGCCCTA
ACAGATTATATCACTCGGCTAGAGGCACTGCAAAGACGACTTGGAACTATACAGTCAGGTTCAACTACTCAATTTCATGCTGGCATGAGA
AGATAATCCTTTGAAACATCATTAATTGAAGTGATTTTAAATAGATTTCCTTTTGTAAATCAATGGTTCTTTTGTGCTTTTGTATTGTGA
ATATTCAATGGGACCAATATGAACACAGCTTATGATTGTATACAAATCCCTTGCCAGCACATGAAAACAAACTGGAATTTGTATATATAA
GCATTGTGTATGTATTCATGCACAATAATTATTGAATTACCTGTATATTTGTGGAATGCTAATTTAAAACATTAAATTATAAACCTTGTG
TATTTATCAAATGGGTGAAAAGATTAAACTTTTACGCATTACAATACTGCTGAATGTGTAGCTCGAGGTGTCCTGCACTTTTCTTATAAG
GCTACTGAAGTTACATGTTTTGCCTAATATATTCTACTGGTGATGAAGACAGATAATATCACTTGTAGAGACCTATTTTTGTATAATGGT

>84305_84305_3_SMURF1-AKAP9_SMURF1_chr7_98741349_ENST00000361125_AKAP9_chr7_91711836_ENST00000359028_length(amino acids)=1180AA_BP=
MVKETNMTSLQKDLSQVRDHLAEAKEKLSILEKEDETEVQESKKACMFEPLPIKLSKSIASQTDGTLKISSSNQTPQILVKNAGIQINLQ
SECSSEEVTEIISQFTEKIEKMQELHAAEILDMESRHISETETLKREHYVAVQLLKEECGTLKAVIQCLRSKEVFGFYNMCFSTLCDSGS
DWGQGIYLTHSQGFDIASEGRGEESESATDSFPKKIKGLLRAVHNEGMQVLSLTESPYSDGEDHSIQQVSEPWLEERKAYINTISSLKDL
ITKMQLQREAEVYDSSQSHESFSDWRGELLLALQQVFLEERSVLLAAFRTELTALGTTDAVGLLNCLEQRIQEQGVEYQAAMECLQKADR
RSLLSEIQALHAQMNGRKITLKREQESEKPSQELLEYNIQQKQSQMLEMQVELSSMKDRATELQEQLSSEKMVVAELKSELAQTKLELET
TLKAQHKHLKELEAFRLEVKDKTDEVHLLNDTLASEQKKSRELQWALEKEKAKLGRSEERDKEELEDLKFSLESQKQRNLQLNLLLEQQK
QLLNESQQKIESQRMLYDAQLSEEQGRNLELQVLLESEKVRIREMSSTLDRERELHAQLQSSDGTGQSRPPLPSEDLLKELQKQLEEKHS
RIVELLNETEKYKLDSLQTRQQMEKDRQVHRKTLQTEQEANTEGQKKMHELQSKVEDLQRQLEEKRQQVYKLDLEGQRLQGIMQEFQKQE
LEREEKRESRRILYQNLNEPTTWSLTSDRTRNWVLQQKIEGETKESNYAKLIEMNGGGTGCNHELEMIRQKLQCVASKLQVLPQKASERL
QFETADDEDFIWVQENIDEIILQLQKLTGQQGEEPSLVSPSTSCGSLTERLLRQNAELTGHISQLTEEKNDLRNMVMKLEEQIRWYRQTG
AGRDNSSRFSLNGGANIEAIIASEKEVWNREKLTLQKSLKRAEAEVYKLKAELRNDSLLQTLSPDSEHVTLKRIYGKYLRAESFRKALIY
QKKYLLLLLGGFQECEDATLALLARMGGQPAFTDLEVITNRPKGFTRFRSAVRVSIAISRMKFLVRRWHRVTGSVSININRDGFGLNQGA
EKTDSFYHSSGGLELYGEPRHTTYRSRSDLDYIRSPLPFQNRYPGTPADFNPGSLACSQLQNYDPDRALTDYITRLEALQRRLGTIQSGS

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>84305_84305_4_SMURF1-AKAP9_SMURF1_chr7_98741349_ENST00000361368_AKAP9_chr7_91711836_ENST00000356239_length(transcript)=4513nt_BP=294nt
CGGCTCGGGACTGGGCTCGGCTGGAAGCAGCGAGGGTCAGAGCGCCGCAGCAAGCGCCGATCTCCCGGCTCGACCATCCGCCTGCCGCCC
GGACGCCTGGGCCGCGGAGTTTGTGTCCCGGCTCGGACCCCGGCGCCCAGCCCGGAGCCGTAACCTTGAGGCGGCGGCGGCGGGGCCGGG
CCGGGCCGGGCTGGGGGGCGGTGGCGCTGGATCCGCGGCTGCCCGATCGTTGGCGGGAGATGTCGAACCCCGGGACACGCAGGAACGGCT
CCAGCATCAAGATCCGTCTGACAGACAACTACTGAGCTATTTCATAGCAATGAAGAAAGTGGATTTTTTAATGAACTCGAGGCTCTTAGA
GCTGAATCAGTGGCTACCAAAGCAGAACTTGCCAGTTATAAAGAAAAGGCTGAAAAACTTCAAGAAGAGCTTTTGGTAAAAGAAACAAAT
ATGACATCTCTTCAGAAAGACTTAAGCCAAGTTAGGGATCACCTCGCAGAGGCAAAAGAGAAATTGTCCATTTTAGAAAAAGAAGATGAG
ACTGAGGTACAAGAAAGCAAAAAGGCCTGCATGTTTGAGCCACTTCCTATAAAACTGAGTAAGAGCATTGCATCCCAGACAGATGGGACT
CTGAAGATCAGTAGCAGCAATCAGACTCCACAAATTCTTGTTAAAAATGCAGGAATACAAATTAATTTACAGAGTGAATGTTCCTCAGAA
GAAGTTACTGAAATAATCAGTCAGTTTACTGAAAAAATTGAGAAGATGCAAGAACTACATGCTGCTGAAATTTTGGACATGGAATCCAGA
CATATTTCAGAAACTGAAACCTTAAAGAGGGAACACTATGTTGCCGTTCAGTTACTGAAAGAGGAATGTGGTACCTTGAAGGCAGTGATA
CAGTGTCTGAGAAGTAAAGAGGGATCCTCAATTCCTGAGCTAGCACATTCTGATGCTTACCAGACTAGAGAAATATGCTCCAGTGATTCT
GGATCAGACTGGGGTCAGGGAATTTATCTTACACACAGTCAGGGATTTGACATAGCATCAGAAGGCCGAGGAGAAGAAAGTGAAAGTGCA
ACAGATTCCTTTCCAAAGAAAATAAAGGGATTACTGAGAGCTGTCCATAATGAAGGCATGCAGGTGCTTTCTCTCACTGAGTCTCCCTAT
AGTGATGGAGAGGACCATTCTATTCAGCAGGTTTCAGAACCTTGGCTAGAAGAGAGAAAAGCTTACATCAATACAATCTCATCTCTAAAG
GATTTAATTACAAAGATGCAACTGCAAAGAGAAGCCGAGGTTTATGATAGTTCTCAATCTCATGAGAGCTTCTCAGACTGGCGAGGTGAA
CTACTGCTTGCCCTTCAACAAGTTTTCTTAGAAGAGCGTAGTGTTTTACTAGCAGCATTTCGGACGGAGCTGACAGCTCTAGGTACTACA
GATGCAGTTGGTTTACTAAACTGTTTGGAACAGAGAATACAAGAACAGGGTGTTGAATATCAAGCAGCTATGGAATGCCTCCAGAAAGCA
GATAGAAGGAGTTTGTTATCTGAAATTCAGGCACTGCATGCACAAATGAATGGTAGGAAAATTACTCTGAAAAGAGAACAAGAGAGTGAG
AAACCAAGCCAAGAACTCTTGGAATATAATATACAGCAGAAGCAGTCTCAAATGCTGGAGATGCAAGTGGAGCTCAGCAGTATGAAAGAC
AGAGCAACGGAACTGCAGGAGCAGCTGAGTTCTGAGAAAATGGTGGTTGCTGAACTGAAGAGTGAGCTTGCACAAACTAAATTGGAACTA
GAAACAACACTCAAGGCACAGCATAAACACCTAAAAGAATTGGAGGCTTTCAGGTTGGAAGTTAAAGATAAGACAGATGAAGTACATTTG
CTTAATGACACATTAGCAAGTGAACAGAAAAAATCAAGAGAGCTCCAGTGGGCTTTGGAGAAAGAGAAAGCCAAGTTGGGACGCAGTGAA
GAACGGGATAAAGAAGAACTTGAGGATCTGAAGTTTTCACTTGAGAGTCAGAAACAAAGGAATCTTCAGCTAAATCTACTTTTGGAACAA
CAGAAACAACTACTGAACGAATCCCAGCAAAAAATAGAATCACAGAGAATGCTATATGATGCCCAGTTGTCAGAAGAACAAGGTCGAAAC
TTAGAGCTTCAGGTACTTCTTGAATCTGAGAAAGTTCGAATTCGGGAAATGAGTAGTACCCTAGATAGGGAGCGGGAATTGCACGCACAG
CTGCAGAGCAGTGATGGTACTGGACAGTCTCGGCCACCCTTGCCCTCAGAGGACCTACTGAAAGAGCTGCAGAAACAGCTAGAGGAAAAA
CACAGTCGCATAGTAGAATTGTTAAATGAGACTGAAAAATATAAACTGGATTCTTTGCAAACACGACAGCAAATGGAAAAAGATAGGCAG
GTTCACAGGAAAACACTGCAGACAGAACAGGAGGCCAACACTGAGGGACAGAAAAAAATGCATGAGCTCCAGTCCAAAGTGGAAGATCTT
CAGCGCCAGCTGGAAGAGAAAAGACAACAAGTTTATAAGTTAGACCTTGAAGGACAGCGACTACAAGGAATCATGCAGGAATTCCAGAAG
CAAGAACTAGAACGAGAAGAAAAACGAGAAAGTAGAAGAATTCTGTATCAGAACCTTAATGAGCCAACCACGTGGAGCTTAACCAGTGAT
AGAACTAGAAATTGGGTTCTTCAACAGAAAATAGAAGGAGAAACAAAAGAATCAAACTACGCTAAATTGATTGAAATGAATGGAGGAGGA
ACCGGCTGTAATCATGAATTAGAAATGATCAGACAAAAGCTTCAATGTGTAGCTTCAAAACTACAGGTTCTACCCCAGAAAGCCTCTGAG
AGACTACAGTTTGAAACAGCAGATGATGAAGATTTCATTTGGGTTCAGGAAAATATTGATGAAATTATTTTACAACTACAGAAATTAACT
GGCCAGCAAGGTGAAGAGCCCAGCTTGGTGTCCCCAAGTACTTCTTGTGGCTCATTGACTGAAAGACTACTGAGACAAAATGCTGAGCTG
ACAGGGCATATCAGTCAACTGACTGAAGAGAAGAATGACTTAAGGAACATGGTTATGAAGCTGGAAGAGCAGATCAGGTGGTATCGACAG
ACAGGAGCTGGTAGAGATAATTCTTCCAGGTTTTCATTGAATGGTGGTGCCAACATTGAAGCCATCATTGCCTCTGAAAAAGAAGTATGG
AACAGAGAAAAATTGACTCTCCAGAAATCTTTGAAAAGGGCAGAGGCTGAAGTATACAAACTGAAAGCTGAACTAAGAAATGACTCTTTA
CTTCAAACTCTGAGCCCTGATTCTGAACATGTCACTTTAAAGAGAATTTATGGTAAATACTTGAGGGCAGAAAGTTTTCGAAAGGCTCTC
ATTTACCAGAAGAAATACCTGCTGCTGTTACTGGGTGGGTTCCAGGAATGTGAAGATGCCACCTTGGCCCTGCTTGCCCGGATGGGGGGG
CAGCCAGCTTTCACGGATCTAGAGGTGATCACCAATCGCCCAAAGGGCTTCACCAGGTTTCGGTCGGCCGTCAGAGTATCCATTGCAATT
TCCAGAATGAAATTTTTGGTTCGACGGTGGCATCGAGTCACAGGTTCTGTTTCCATCAATATTAACAGAGATGGCTTTGGACTGAATCAA
GGTGCAGAAAAGACTGACTCATTTTATCATTCTTCTGGTGGGCTGGAGTTATATGGAGAACCAAGACATACTACGTATCGCTCAAGATCA
GATCTGGACTATATTAGGTCCCCTTTACCATTTCAGAATAGGTACCCAGGCACTCCAGCTGATTTCAATCCTGGTTCTTTAGCATGTTCT
CAGCTTCAGAATTACGATCCTGACAGAGCCCTAACAGATTATATCACTCGGCTAGAGGCACTGCAAAGACGACTTGGAACTATACAGTCA
GGTTCAACTACTCAATTTCATGCTGGCATGAGAAGATAATCCTTTGAAACATCATTAATTGAAGTGATTTTAAATAGATTTCCTTTTGTA
AATCAATGGTTCTTTTGTGCTTTTGTATTGTGAATATTCAATGGGACCAATATGAACACAGCTTATGATTGTATACAAATCCCTTGCCAG
CACATGAAAACAAACTGGAATTTGTATATATAAGCATTGTGTATGTATTCATGCACAATAATTATTGAATTACCTGTATATTTGTGGAAT
GCTAATTTAAAACATTAAATTATAAACCTTGTGTATTTATCAAATGGGTGAAAAGATTAAACTTTTACGCATTACAATACTGCTGAATGT
GTAGCTCGAGGTGTCCTGCACTTTTCTTATAAGGCTACTGAAGTTACATGTTTTGCCTAATATATTCTACTGGTGATGAAGACAGATAAT
ATCACTTGTAGAGACCTATTTTTGTATAATGGTAGAAGTTTTGAATTTTATGGGGTATTTTGTCAAGTACTGAAATAAAAATGACTTCAC

>84305_84305_4_SMURF1-AKAP9_SMURF1_chr7_98741349_ENST00000361368_AKAP9_chr7_91711836_ENST00000356239_length(amino acids)=1188AA_BP=
MVKETNMTSLQKDLSQVRDHLAEAKEKLSILEKEDETEVQESKKACMFEPLPIKLSKSIASQTDGTLKISSSNQTPQILVKNAGIQINLQ
SECSSEEVTEIISQFTEKIEKMQELHAAEILDMESRHISETETLKREHYVAVQLLKEECGTLKAVIQCLRSKEGSSIPELAHSDAYQTRE
ICSSDSGSDWGQGIYLTHSQGFDIASEGRGEESESATDSFPKKIKGLLRAVHNEGMQVLSLTESPYSDGEDHSIQQVSEPWLEERKAYIN
TISSLKDLITKMQLQREAEVYDSSQSHESFSDWRGELLLALQQVFLEERSVLLAAFRTELTALGTTDAVGLLNCLEQRIQEQGVEYQAAM
ECLQKADRRSLLSEIQALHAQMNGRKITLKREQESEKPSQELLEYNIQQKQSQMLEMQVELSSMKDRATELQEQLSSEKMVVAELKSELA
QTKLELETTLKAQHKHLKELEAFRLEVKDKTDEVHLLNDTLASEQKKSRELQWALEKEKAKLGRSEERDKEELEDLKFSLESQKQRNLQL
NLLLEQQKQLLNESQQKIESQRMLYDAQLSEEQGRNLELQVLLESEKVRIREMSSTLDRERELHAQLQSSDGTGQSRPPLPSEDLLKELQ
KQLEEKHSRIVELLNETEKYKLDSLQTRQQMEKDRQVHRKTLQTEQEANTEGQKKMHELQSKVEDLQRQLEEKRQQVYKLDLEGQRLQGI
MQEFQKQELEREEKRESRRILYQNLNEPTTWSLTSDRTRNWVLQQKIEGETKESNYAKLIEMNGGGTGCNHELEMIRQKLQCVASKLQVL
PQKASERLQFETADDEDFIWVQENIDEIILQLQKLTGQQGEEPSLVSPSTSCGSLTERLLRQNAELTGHISQLTEEKNDLRNMVMKLEEQ
IRWYRQTGAGRDNSSRFSLNGGANIEAIIASEKEVWNREKLTLQKSLKRAEAEVYKLKAELRNDSLLQTLSPDSEHVTLKRIYGKYLRAE
SFRKALIYQKKYLLLLLGGFQECEDATLALLARMGGQPAFTDLEVITNRPKGFTRFRSAVRVSIAISRMKFLVRRWHRVTGSVSININRD
GFGLNQGAEKTDSFYHSSGGLELYGEPRHTTYRSRSDLDYIRSPLPFQNRYPGTPADFNPGSLACSQLQNYDPDRALTDYITRLEALQRR

--------------------------------------------------------------
>84305_84305_5_SMURF1-AKAP9_SMURF1_chr7_98741349_ENST00000361368_AKAP9_chr7_91711836_ENST00000358100_length(transcript)=4327nt_BP=294nt
CGGCTCGGGACTGGGCTCGGCTGGAAGCAGCGAGGGTCAGAGCGCCGCAGCAAGCGCCGATCTCCCGGCTCGACCATCCGCCTGCCGCCC
GGACGCCTGGGCCGCGGAGTTTGTGTCCCGGCTCGGACCCCGGCGCCCAGCCCGGAGCCGTAACCTTGAGGCGGCGGCGGCGGGGCCGGG
CCGGGCCGGGCTGGGGGGCGGTGGCGCTGGATCCGCGGCTGCCCGATCGTTGGCGGGAGATGTCGAACCCCGGGACACGCAGGAACGGCT
CCAGCATCAAGATCCGTCTGACAGACAACTACTGAGCTATTTCATAGCAATGAAGAAAGTGGATTTTTTAATGAACTCGAGGCTCTTAGA
GCTGAATCAGTGGCTACCAAAGCAGAACTTGCCAGTTATAAAGAAAAGGCTGAAAAACTTCAAGAAGAGCTTTTGGTAAAAGAAACAAAT
ATGACATCTCTTCAGAAAGACTTAAGCCAAGTTAGGGATCACCTCGCAGAGGCAAAAGAGAAATTGTCCATTTTAGAAAAAGAAGATGAG
ACTGAGGTACAAGAAAGCAAAAAGGCCTGCATGTTTGAGCCACTTCCTATAAAACTGAGTAAGAGCATTGCATCCCAGACAGATGGGACT
CTGAAGATCAGTAGCAGCAATCAGACTCCACAAATTCTTGTTAAAAATGCAGGAATACAAATTAATTTACAGAGTGAATGTTCCTCAGAA
GAAGTTACTGAAATAATCAGTCAGTTTACTGAAAAAATTGAGAAGATGCAAGAACTACATGCTGCTGAAATTTTGGACATGGAATCCAGA
CATATTTCAGAAACTGAAACCTTAAAGAGGGAACACTATGTTGCCGTTCAGTTACTGAAAGAGGAATGTGGTACCTTGAAGGCAGTGATA
CAGTGTCTGAGAAGTAAAGAGGGATTACTGAGAGCTGTCCATAATGAAGGCATGCAGGTGCTTTCTCTCACTGAGTCTCCCTATAGTGAT
GGAGAGGACCATTCTATTCAGCAGGTTTCAGAACCTTGGCTAGAAGAGAGAAAAGCTTACATCAATACAATCTCATCTCTAAAGGATTTA
ATTACAAAGATGCAACTGCAAAGAGAAGCCGAGGTTTATGATAGTTCTCAATCTCATGAGAGCTTCTCAGACTGGCGAGGTGAACTACTG
CTTGCCCTTCAACAAGTTTTCTTAGAAGAGCGTAGTGTTTTACTAGCAGCATTTCGGACGGAGCTGACAGCTCTAGGTACTACAGATGCA
GTTGGTTTACTAAACTGTTTGGAACAGAGAATACAAGAACAGGGTGTTGAATATCAAGCAGCTATGGAATGCCTCCAGAAAGCAGATAGA
AGGAGTTTGTTATCTGAAATTCAGGCACTGCATGCACAAATGAATGGTAGGAAAATTACTCTGAAAAGAGAACAAGAGAGTGAGAAACCA
AGCCAAGAACTCTTGGAATATAATATACAGCAGAAGCAGTCTCAAATGCTGGAGATGCAAGTGGAGCTCAGCAGTATGAAAGACAGAGCA
ACGGAACTGCAGGAGCAGCTGAGTTCTGAGAAAATGGTGGTTGCTGAACTGAAGAGTGAGCTTGCACAAACTAAATTGGAACTAGAAACA
ACACTCAAGGCACAGCATAAACACCTAAAAGAATTGGAGGCTTTCAGGTTGGAAGTTAAAGATAAGACAGATGAAGTACATTTGCTTAAT
GACACATTAGCAAGTGAACAGAAAAAATCAAGAGAGCTCCAGTGGGCTTTGGAGAAAGAGAAAGCCAAGTTGGGACGCAGTGAAGAACGG
GATAAAGAAGAACTTGAGGATCTGAAGTTTTCACTTGAGAGTCAGAAACAAAGGAATCTTCAGCTAAATCTACTTTTGGAACAACAGAAA
CAACTACTGAACGAATCCCAGCAAAAAATAGAATCACAGAGAATGCTATATGATGCCCAGTTGTCAGAAGAACAAGGTCGAAACTTAGAG
CTTCAGGTACTTCTTGAATCTGAGAAAGTTCGAATTCGGGAAATGAGTAGTACCCTAGATAGGGAGCGGGAATTGCACGCACAGCTGCAG
AGCAGTGATGGTACTGGACAGTCTCGGCCACCCTTGCCCTCAGAGGACCTACTGAAAGAGCTGCAGAAACAGCTAGAGGAAAAACACAGT
CGCATAGTAGAATTGTTAAATGAGACTGAAAAATATAAACTGGATTCTTTGCAAACACGACAGCAAATGGAAAAAGATAGGCAGGTTCAC
AGGAAAACACTGCAGACAGAACAGGAGGCCAACACTGAGGGACAGAAAAAAATGCATGAGCTCCAGTCCAAAGTGGAAGATCTTCAGCGC
CAGCTGGAAGAGAAAAGACAACAAGTTTATAAGTTAGACCTTGAAGGACAGCGACTACAAGGAATCATGCAGGAATTCCAGAAGCAAGAA
CTAGAACGAGAAGAAAAACGAGAAAGTAGAAGAATTCTGTATCAGAACCTTAATGAGCCAACCACGTGGAGCTTAACCAGTGATAGAACT
AGAAATTGGGTTCTTCAACAGAAAATAGAAGGAGAAACAAAAGAATCAAACTACGCTAAATTGATTGAAATGAATGGAGGAGGAACCGGC
TGTAATCATGAATTAGAAATGATCAGACAAAAGCTTCAATGTGTAGCTTCAAAACTACAGGTTCTACCCCAGAAAGCCTCTGAGAGACTA
CAGTTTGAAACAGCAGATGATGAAGATTTCATTTGGGTTCAGGAAAATATTGATGAAATTATTTTACAACTACAGAAATTAACTGGCCAG
CAAGGTGAAGAGCCCAGCTTGGTGTCCCCAAGTACTTCTTGTGGCTCATTGACTGAAAGACTACTGAGACAAAATGCTGAGCTGACAGGG
CATATCAGTCAACTGACTGAAGAGAAGAATGACTTAAGGAACATGGTTATGAAGCTGGAAGAGCAGATCAGGTGGTATCGACAGACAGGA
GCTGGTAGAGATAATTCTTCCAGGTTTTCATTGAATGGTGGTGCCAACATTGAAGCCATCATTGCCTCTGAAAAAGAAGTATGGAACAGA
GAAAAATTGACTCTCCAGAAATCTTTGAAAAGGGCAGAGGCTGAAGTATACAAACTGAAAGCTGAACTAAGAAATGACTCTTTACTTCAA
ACTCTGAGCCCTGATTCTGAACATGTCACTTTAAAGAGAATTTATGGTAAATACTTGAGGGCAGAAAGTTTTCGAAAGGCTCTCATTTAC
CAGAAGAAATACCTGCTGCTGTTACTGGGTGGGTTCCAGGAATGTGAAGATGCCACCTTGGCCCTGCTTGCCCGGATGGGGGGGCAGCCA
GCTTTCACGGATCTAGAGGTGATCACCAATCGCCCAAAGGGCTTCACCAGGTTTCGGTCGGCCGTCAGAGTATCCATTGCAATTTCCAGA
ATGAAATTTTTGGTTCGACGGTGGCATCGAGTCACAGGTTCTGTTTCCATCAATATTAACAGAGATGGCTTTGGACTGAATCAAGGTGCA
GAAAAGACTGACTCATTTTATCATTCTTCTGGTGGGCTGGAGTTATATGGAGAACCAAGACATACTACGTATCGCTCAAGATCAGATCTG
GACTATATTAGGTCCCCTTTACCATTTCAGAATAGGTACCCAGGCACTCCAGCTGATTTCAATCCTGGTTCTTTAGCATGTTCTCAGCTT
CAGAATTACGATCCTGACAGAGCCCTAACAGATTATATCACTCGGCTAGAGGCACTGCAAAGACGACTTGGAACTATACAGTCAGGTTCA
ACTACTCAATTTCATGCTGGCATGAGAAGATAATCCTTTGAAACATCATTAATTGAAGTGATTTTAAATAGATTTCCTTTTGTAAATCAA
TGGTTCTTTTGTGCTTTTGTATTGTGAATATTCAATGGGACCAATATGAACACAGCTTATGATTGTATACAAATCCCTTGCCAGCACATG
AAAACAAACTGGAATTTGTATATATAAGCATTGTGTATGTATTCATGCACAATAATTATTGAATTACCTGTATATTTGTGGAATGCTAAT
TTAAAACATTAAATTATAAACCTTGTGTATTTATCAAATGGGTGAAAAGATTAAACTTTTACGCATTACAATACTGCTGAATGTGTAGCT
CGAGGTGTCCTGCACTTTTCTTATAAGGCTACTGAAGTTACATGTTTTGCCTAATATATTCTACTGGTGATGAAGACAGATAATATCACT
TGTAGAGACCTATTTTTGTATAATGGTAGAAGTTTTGAATTTTATGGGGTATTTTGTCAAGTACTGAAATAAAAATGACTTCACCATTTT

>84305_84305_5_SMURF1-AKAP9_SMURF1_chr7_98741349_ENST00000361368_AKAP9_chr7_91711836_ENST00000358100_length(amino acids)=1126AA_BP=
MVKETNMTSLQKDLSQVRDHLAEAKEKLSILEKEDETEVQESKKACMFEPLPIKLSKSIASQTDGTLKISSSNQTPQILVKNAGIQINLQ
SECSSEEVTEIISQFTEKIEKMQELHAAEILDMESRHISETETLKREHYVAVQLLKEECGTLKAVIQCLRSKEGLLRAVHNEGMQVLSLT
ESPYSDGEDHSIQQVSEPWLEERKAYINTISSLKDLITKMQLQREAEVYDSSQSHESFSDWRGELLLALQQVFLEERSVLLAAFRTELTA
LGTTDAVGLLNCLEQRIQEQGVEYQAAMECLQKADRRSLLSEIQALHAQMNGRKITLKREQESEKPSQELLEYNIQQKQSQMLEMQVELS
SMKDRATELQEQLSSEKMVVAELKSELAQTKLELETTLKAQHKHLKELEAFRLEVKDKTDEVHLLNDTLASEQKKSRELQWALEKEKAKL
GRSEERDKEELEDLKFSLESQKQRNLQLNLLLEQQKQLLNESQQKIESQRMLYDAQLSEEQGRNLELQVLLESEKVRIREMSSTLDRERE
LHAQLQSSDGTGQSRPPLPSEDLLKELQKQLEEKHSRIVELLNETEKYKLDSLQTRQQMEKDRQVHRKTLQTEQEANTEGQKKMHELQSK
VEDLQRQLEEKRQQVYKLDLEGQRLQGIMQEFQKQELEREEKRESRRILYQNLNEPTTWSLTSDRTRNWVLQQKIEGETKESNYAKLIEM
NGGGTGCNHELEMIRQKLQCVASKLQVLPQKASERLQFETADDEDFIWVQENIDEIILQLQKLTGQQGEEPSLVSPSTSCGSLTERLLRQ
NAELTGHISQLTEEKNDLRNMVMKLEEQIRWYRQTGAGRDNSSRFSLNGGANIEAIIASEKEVWNREKLTLQKSLKRAEAEVYKLKAELR
NDSLLQTLSPDSEHVTLKRIYGKYLRAESFRKALIYQKKYLLLLLGGFQECEDATLALLARMGGQPAFTDLEVITNRPKGFTRFRSAVRV
SIAISRMKFLVRRWHRVTGSVSININRDGFGLNQGAEKTDSFYHSSGGLELYGEPRHTTYRSRSDLDYIRSPLPFQNRYPGTPADFNPGS

--------------------------------------------------------------
>84305_84305_6_SMURF1-AKAP9_SMURF1_chr7_98741349_ENST00000361368_AKAP9_chr7_91711836_ENST00000359028_length(transcript)=4489nt_BP=294nt
CGGCTCGGGACTGGGCTCGGCTGGAAGCAGCGAGGGTCAGAGCGCCGCAGCAAGCGCCGATCTCCCGGCTCGACCATCCGCCTGCCGCCC
GGACGCCTGGGCCGCGGAGTTTGTGTCCCGGCTCGGACCCCGGCGCCCAGCCCGGAGCCGTAACCTTGAGGCGGCGGCGGCGGGGCCGGG
CCGGGCCGGGCTGGGGGGCGGTGGCGCTGGATCCGCGGCTGCCCGATCGTTGGCGGGAGATGTCGAACCCCGGGACACGCAGGAACGGCT
CCAGCATCAAGATCCGTCTGACAGACAACTACTGAGCTATTTCATAGCAATGAAGAAAGTGGATTTTTTAATGAACTCGAGGCTCTTAGA
GCTGAATCAGTGGCTACCAAAGCAGAACTTGCCAGTTATAAAGAAAAGGCTGAAAAACTTCAAGAAGAGCTTTTGGTAAAAGAAACAAAT
ATGACATCTCTTCAGAAAGACTTAAGCCAAGTTAGGGATCACCTCGCAGAGGCAAAAGAGAAATTGTCCATTTTAGAAAAAGAAGATGAG
ACTGAGGTACAAGAAAGCAAAAAGGCCTGCATGTTTGAGCCACTTCCTATAAAACTGAGTAAGAGCATTGCATCCCAGACAGATGGGACT
CTGAAGATCAGTAGCAGCAATCAGACTCCACAAATTCTTGTTAAAAATGCAGGAATACAAATTAATTTACAGAGTGAATGTTCCTCAGAA
GAAGTTACTGAAATAATCAGTCAGTTTACTGAAAAAATTGAGAAGATGCAAGAACTACATGCTGCTGAAATTTTGGACATGGAATCCAGA
CATATTTCAGAAACTGAAACCTTAAAGAGGGAACACTATGTTGCCGTTCAGTTACTGAAAGAGGAATGTGGTACCTTGAAGGCAGTGATA
CAGTGTCTGAGAAGTAAAGAGGTATTTGGTTTTTATAATATGTGTTTTTCAACATTGTGTGATTCTGGATCAGACTGGGGTCAGGGAATT
TATCTTACACACAGTCAGGGATTTGACATAGCATCAGAAGGCCGAGGAGAAGAAAGTGAAAGTGCAACAGATTCCTTTCCAAAGAAAATA
AAGGGATTACTGAGAGCTGTCCATAATGAAGGCATGCAGGTGCTTTCTCTCACTGAGTCTCCCTATAGTGATGGAGAGGACCATTCTATT
CAGCAGGTTTCAGAACCTTGGCTAGAAGAGAGAAAAGCTTACATCAATACAATCTCATCTCTAAAGGATTTAATTACAAAGATGCAACTG
CAAAGAGAAGCCGAGGTTTATGATAGTTCTCAATCTCATGAGAGCTTCTCAGACTGGCGAGGTGAACTACTGCTTGCCCTTCAACAAGTT
TTCTTAGAAGAGCGTAGTGTTTTACTAGCAGCATTTCGGACGGAGCTGACAGCTCTAGGTACTACAGATGCAGTTGGTTTACTAAACTGT
TTGGAACAGAGAATACAAGAACAGGGTGTTGAATATCAAGCAGCTATGGAATGCCTCCAGAAAGCAGATAGAAGGAGTTTGTTATCTGAA
ATTCAGGCACTGCATGCACAAATGAATGGTAGGAAAATTACTCTGAAAAGAGAACAAGAGAGTGAGAAACCAAGCCAAGAACTCTTGGAA
TATAATATACAGCAGAAGCAGTCTCAAATGCTGGAGATGCAAGTGGAGCTCAGCAGTATGAAAGACAGAGCAACGGAACTGCAGGAGCAG
CTGAGTTCTGAGAAAATGGTGGTTGCTGAACTGAAGAGTGAGCTTGCACAAACTAAATTGGAACTAGAAACAACACTCAAGGCACAGCAT
AAACACCTAAAAGAATTGGAGGCTTTCAGGTTGGAAGTTAAAGATAAGACAGATGAAGTACATTTGCTTAATGACACATTAGCAAGTGAA
CAGAAAAAATCAAGAGAGCTCCAGTGGGCTTTGGAGAAAGAGAAAGCCAAGTTGGGACGCAGTGAAGAACGGGATAAAGAAGAACTTGAG
GATCTGAAGTTTTCACTTGAGAGTCAGAAACAAAGGAATCTTCAGCTAAATCTACTTTTGGAACAACAGAAACAACTACTGAACGAATCC
CAGCAAAAAATAGAATCACAGAGAATGCTATATGATGCCCAGTTGTCAGAAGAACAAGGTCGAAACTTAGAGCTTCAGGTACTTCTTGAA
TCTGAGAAAGTTCGAATTCGGGAAATGAGTAGTACCCTAGATAGGGAGCGGGAATTGCACGCACAGCTGCAGAGCAGTGATGGTACTGGA
CAGTCTCGGCCACCCTTGCCCTCAGAGGACCTACTGAAAGAGCTGCAGAAACAGCTAGAGGAAAAACACAGTCGCATAGTAGAATTGTTA
AATGAGACTGAAAAATATAAACTGGATTCTTTGCAAACACGACAGCAAATGGAAAAAGATAGGCAGGTTCACAGGAAAACACTGCAGACA
GAACAGGAGGCCAACACTGAGGGACAGAAAAAAATGCATGAGCTCCAGTCCAAAGTGGAAGATCTTCAGCGCCAGCTGGAAGAGAAAAGA
CAACAAGTTTATAAGTTAGACCTTGAAGGACAGCGACTACAAGGAATCATGCAGGAATTCCAGAAGCAAGAACTAGAACGAGAAGAAAAA
CGAGAAAGTAGAAGAATTCTGTATCAGAACCTTAATGAGCCAACCACGTGGAGCTTAACCAGTGATAGAACTAGAAATTGGGTTCTTCAA
CAGAAAATAGAAGGAGAAACAAAAGAATCAAACTACGCTAAATTGATTGAAATGAATGGAGGAGGAACCGGCTGTAATCATGAATTAGAA
ATGATCAGACAAAAGCTTCAATGTGTAGCTTCAAAACTACAGGTTCTACCCCAGAAAGCCTCTGAGAGACTACAGTTTGAAACAGCAGAT
GATGAAGATTTCATTTGGGTTCAGGAAAATATTGATGAAATTATTTTACAACTACAGAAATTAACTGGCCAGCAAGGTGAAGAGCCCAGC
TTGGTGTCCCCAAGTACTTCTTGTGGCTCATTGACTGAAAGACTACTGAGACAAAATGCTGAGCTGACAGGGCATATCAGTCAACTGACT
GAAGAGAAGAATGACTTAAGGAACATGGTTATGAAGCTGGAAGAGCAGATCAGGTGGTATCGACAGACAGGAGCTGGTAGAGATAATTCT
TCCAGGTTTTCATTGAATGGTGGTGCCAACATTGAAGCCATCATTGCCTCTGAAAAAGAAGTATGGAACAGAGAAAAATTGACTCTCCAG
AAATCTTTGAAAAGGGCAGAGGCTGAAGTATACAAACTGAAAGCTGAACTAAGAAATGACTCTTTACTTCAAACTCTGAGCCCTGATTCT
GAACATGTCACTTTAAAGAGAATTTATGGTAAATACTTGAGGGCAGAAAGTTTTCGAAAGGCTCTCATTTACCAGAAGAAATACCTGCTG
CTGTTACTGGGTGGGTTCCAGGAATGTGAAGATGCCACCTTGGCCCTGCTTGCCCGGATGGGGGGGCAGCCAGCTTTCACGGATCTAGAG
GTGATCACCAATCGCCCAAAGGGCTTCACCAGGTTTCGGTCGGCCGTCAGAGTATCCATTGCAATTTCCAGAATGAAATTTTTGGTTCGA
CGGTGGCATCGAGTCACAGGTTCTGTTTCCATCAATATTAACAGAGATGGCTTTGGACTGAATCAAGGTGCAGAAAAGACTGACTCATTT
TATCATTCTTCTGGTGGGCTGGAGTTATATGGAGAACCAAGACATACTACGTATCGCTCAAGATCAGATCTGGACTATATTAGGTCCCCT
TTACCATTTCAGAATAGGTACCCAGGCACTCCAGCTGATTTCAATCCTGGTTCTTTAGCATGTTCTCAGCTTCAGAATTACGATCCTGAC
AGAGCCCTAACAGATTATATCACTCGGCTAGAGGCACTGCAAAGACGACTTGGAACTATACAGTCAGGTTCAACTACTCAATTTCATGCT
GGCATGAGAAGATAATCCTTTGAAACATCATTAATTGAAGTGATTTTAAATAGATTTCCTTTTGTAAATCAATGGTTCTTTTGTGCTTTT
GTATTGTGAATATTCAATGGGACCAATATGAACACAGCTTATGATTGTATACAAATCCCTTGCCAGCACATGAAAACAAACTGGAATTTG
TATATATAAGCATTGTGTATGTATTCATGCACAATAATTATTGAATTACCTGTATATTTGTGGAATGCTAATTTAAAACATTAAATTATA
AACCTTGTGTATTTATCAAATGGGTGAAAAGATTAAACTTTTACGCATTACAATACTGCTGAATGTGTAGCTCGAGGTGTCCTGCACTTT
TCTTATAAGGCTACTGAAGTTACATGTTTTGCCTAATATATTCTACTGGTGATGAAGACAGATAATATCACTTGTAGAGACCTATTTTTG

>84305_84305_6_SMURF1-AKAP9_SMURF1_chr7_98741349_ENST00000361368_AKAP9_chr7_91711836_ENST00000359028_length(amino acids)=1180AA_BP=
MVKETNMTSLQKDLSQVRDHLAEAKEKLSILEKEDETEVQESKKACMFEPLPIKLSKSIASQTDGTLKISSSNQTPQILVKNAGIQINLQ
SECSSEEVTEIISQFTEKIEKMQELHAAEILDMESRHISETETLKREHYVAVQLLKEECGTLKAVIQCLRSKEVFGFYNMCFSTLCDSGS
DWGQGIYLTHSQGFDIASEGRGEESESATDSFPKKIKGLLRAVHNEGMQVLSLTESPYSDGEDHSIQQVSEPWLEERKAYINTISSLKDL
ITKMQLQREAEVYDSSQSHESFSDWRGELLLALQQVFLEERSVLLAAFRTELTALGTTDAVGLLNCLEQRIQEQGVEYQAAMECLQKADR
RSLLSEIQALHAQMNGRKITLKREQESEKPSQELLEYNIQQKQSQMLEMQVELSSMKDRATELQEQLSSEKMVVAELKSELAQTKLELET
TLKAQHKHLKELEAFRLEVKDKTDEVHLLNDTLASEQKKSRELQWALEKEKAKLGRSEERDKEELEDLKFSLESQKQRNLQLNLLLEQQK
QLLNESQQKIESQRMLYDAQLSEEQGRNLELQVLLESEKVRIREMSSTLDRERELHAQLQSSDGTGQSRPPLPSEDLLKELQKQLEEKHS
RIVELLNETEKYKLDSLQTRQQMEKDRQVHRKTLQTEQEANTEGQKKMHELQSKVEDLQRQLEEKRQQVYKLDLEGQRLQGIMQEFQKQE
LEREEKRESRRILYQNLNEPTTWSLTSDRTRNWVLQQKIEGETKESNYAKLIEMNGGGTGCNHELEMIRQKLQCVASKLQVLPQKASERL
QFETADDEDFIWVQENIDEIILQLQKLTGQQGEEPSLVSPSTSCGSLTERLLRQNAELTGHISQLTEEKNDLRNMVMKLEEQIRWYRQTG
AGRDNSSRFSLNGGANIEAIIASEKEVWNREKLTLQKSLKRAEAEVYKLKAELRNDSLLQTLSPDSEHVTLKRIYGKYLRAESFRKALIY
QKKYLLLLLGGFQECEDATLALLARMGGQPAFTDLEVITNRPKGFTRFRSAVRVSIAISRMKFLVRRWHRVTGSVSININRDGFGLNQGA
EKTDSFYHSSGGLELYGEPRHTTYRSRSDLDYIRSPLPFQNRYPGTPADFNPGSLACSQLQNYDPDRALTDYITRLEALQRRLGTIQSGS

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Fusion Gene PPI Analysis for SMURF1-AKAP9


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for SMURF1-AKAP9


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for SMURF1-AKAP9


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource