FusionGDB Logo

Home

Download

Statistics

Examples

Help

Contact
Center for Computational Systems Medicine
leaf

Fusion Gene Summary

leaf

Fusion Gene ORF analysis

leaf

Fusion Genomic Features

leaf

Fusion Protein Features

leaf

Fusion Gene Sequence

leaf

Fusion Gene PPI analysis

leaf

Related Drugs

leaf

Related Diseases

Fusion gene:SMURF1-TRIM4 (FusionGDB2 ID:84326)

Fusion Gene Summary for SMURF1-TRIM4

check button Fusion gene summary
Fusion gene informationFusion gene name: SMURF1-TRIM4
Fusion gene ID: 84326
HgeneTgene
Gene symbol

SMURF1

TRIM4

Gene ID

57154

89122

Gene nameSMAD specific E3 ubiquitin protein ligase 1tripartite motif containing 4
Synonyms-RNF87
Cytomap

7q22.1

7q22.1

Type of geneprotein-codingprotein-coding
DescriptionE3 ubiquitin-protein ligase SMURF1E3 ubiquitin ligase SMURF1HECT-type E3 ubiquitin transferase SMURF1Smad ubiquitination regulatory factor 1Smad-specific E3 ubiquitin ligase 1hSMURF1E3 ubiquitin-protein ligase TRIM4RING finger protein 87RING-type E3 ubiquitin transferase TRIM4tripartite motif protein 4
Modification date2020031320200313
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000361125, ENST00000361368, 
ENST00000480055, 		ENST00000349062, 
ENST00000354241, ENST00000355947, 
Fusion gene scores* DoF score19 X 8 X 12=18243 X 3 X 3=27
# samples 244
** MAII scorelog2(24/1824*10)=-2.92599941855622
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(4/27*10)=0.567040592723894
effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs).
DoF>8 and MAII>0
Context

PubMed: SMURF1 [Title/Abstract] AND TRIM4 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointSMURF1(98741349)-TRIM4(99507283), # samples:3
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneSMURF1

GO:0000209

protein polyubiquitination

19937093

HgeneSMURF1

GO:0006511

ubiquitin-dependent protein catabolic process

10458166|12151385|19937093

HgeneSMURF1

GO:0006611

protein export from nucleus

11278251

HgeneSMURF1

GO:0016567

protein ubiquitination

11278251

HgeneSMURF1

GO:0030154

cell differentiation

10458166

HgeneSMURF1

GO:0030509

BMP signaling pathway

21572392

HgeneSMURF1

GO:0030512

negative regulation of transforming growth factor beta receptor signaling pathway

11278251|12151385

HgeneSMURF1

GO:0030514

negative regulation of BMP signaling pathway

27214554

HgeneSMURF1

GO:0030579

ubiquitin-dependent SMAD protein catabolic process

11278251|12151385

HgeneSMURF1

GO:0032801

receptor catabolic process

12151385

HgeneSMURF1

GO:0034394

protein localization to cell surface

12151385

HgeneSMURF1

GO:0043161

proteasome-mediated ubiquitin-dependent protein catabolic process

11278251

HgeneSMURF1

GO:1903861

positive regulation of dendrite extension

23999003


check buttonFusion gene breakpoints across SMURF1 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across TRIM4 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4LGGTCGA-FG-5963-01ASMURF1chr7

98741349

-TRIM4chr7

99507283

-
ChimerDB4LGGTCGA-FG-5963-02ASMURF1chr7

98741349

-TRIM4chr7

99507283

-
ChimerDB4LGGTCGA-FG-5963SMURF1chr7

98741348

-TRIM4chr7

99507283

-


Top

Fusion Gene ORF analysis for SMURF1-TRIM4

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
In-frameENST00000361125ENST00000349062SMURF1chr7

98741349

-TRIM4chr7

99507283

-
In-frameENST00000361125ENST00000349062SMURF1chr7

98741348

-TRIM4chr7

99507283

-
In-frameENST00000361125ENST00000354241SMURF1chr7

98741349

-TRIM4chr7

99507283

-
In-frameENST00000361125ENST00000354241SMURF1chr7

98741348

-TRIM4chr7

99507283

-
In-frameENST00000361125ENST00000355947SMURF1chr7

98741349

-TRIM4chr7

99507283

-
In-frameENST00000361125ENST00000355947SMURF1chr7

98741348

-TRIM4chr7

99507283

-
In-frameENST00000361368ENST00000349062SMURF1chr7

98741349

-TRIM4chr7

99507283

-
In-frameENST00000361368ENST00000349062SMURF1chr7

98741348

-TRIM4chr7

99507283

-
In-frameENST00000361368ENST00000354241SMURF1chr7

98741349

-TRIM4chr7

99507283

-
In-frameENST00000361368ENST00000354241SMURF1chr7

98741348

-TRIM4chr7

99507283

-
In-frameENST00000361368ENST00000355947SMURF1chr7

98741349

-TRIM4chr7

99507283

-
In-frameENST00000361368ENST00000355947SMURF1chr7

98741348

-TRIM4chr7

99507283

-
intron-3CDSENST00000480055ENST00000349062SMURF1chr7

98741349

-TRIM4chr7

99507283

-
intron-3CDSENST00000480055ENST00000349062SMURF1chr7

98741348

-TRIM4chr7

99507283

-
intron-3CDSENST00000480055ENST00000354241SMURF1chr7

98741349

-TRIM4chr7

99507283

-
intron-3CDSENST00000480055ENST00000354241SMURF1chr7

98741348

-TRIM4chr7

99507283

-
intron-3CDSENST00000480055ENST00000355947SMURF1chr7

98741349

-TRIM4chr7

99507283

-
intron-3CDSENST00000480055ENST00000355947SMURF1chr7

98741348

-TRIM4chr7

99507283

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000361368SMURF1chr798741349-ENST00000355947TRIM4chr799507283-30762943331325330
ENST00000361368SMURF1chr798741349-ENST00000349062TRIM4chr799507283-30762943331325330
ENST00000361368SMURF1chr798741349-ENST00000354241TRIM4chr799507283-1751294333785150
ENST00000361125SMURF1chr798741349-ENST00000355947TRIM4chr799507283-31573754141406330
ENST00000361125SMURF1chr798741349-ENST00000349062TRIM4chr799507283-31573754141406330
ENST00000361125SMURF1chr798741349-ENST00000354241TRIM4chr799507283-1832375414866150
ENST00000361368SMURF1chr798741348-ENST00000355947TRIM4chr799507283-30762943331325330
ENST00000361368SMURF1chr798741348-ENST00000349062TRIM4chr799507283-30762943331325330
ENST00000361368SMURF1chr798741348-ENST00000354241TRIM4chr799507283-1751294333785150
ENST00000361125SMURF1chr798741348-ENST00000355947TRIM4chr799507283-31573754141406330
ENST00000361125SMURF1chr798741348-ENST00000349062TRIM4chr799507283-31573754141406330
ENST00000361125SMURF1chr798741348-ENST00000354241TRIM4chr799507283-1832375414866150

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000361368ENST00000355947SMURF1chr798741349-TRIM4chr799507283-0.000330520.99966943
ENST00000361368ENST00000349062SMURF1chr798741349-TRIM4chr799507283-0.000330520.99966943
ENST00000361368ENST00000354241SMURF1chr798741349-TRIM4chr799507283-0.0072607940.99273926
ENST00000361125ENST00000355947SMURF1chr798741349-TRIM4chr799507283-0.0003357820.9996642
ENST00000361125ENST00000349062SMURF1chr798741349-TRIM4chr799507283-0.0003357820.9996642
ENST00000361125ENST00000354241SMURF1chr798741349-TRIM4chr799507283-0.0057473110.9942526
ENST00000361368ENST00000355947SMURF1chr798741348-TRIM4chr799507283-0.000330520.99966943
ENST00000361368ENST00000349062SMURF1chr798741348-TRIM4chr799507283-0.000330520.99966943
ENST00000361368ENST00000354241SMURF1chr798741348-TRIM4chr799507283-0.0072607940.99273926
ENST00000361125ENST00000355947SMURF1chr798741348-TRIM4chr799507283-0.0003357820.9996642
ENST00000361125ENST00000349062SMURF1chr798741348-TRIM4chr799507283-0.0003357820.9996642
ENST00000361125ENST00000354241SMURF1chr798741348-TRIM4chr799507283-0.0057473110.9942526

Top

Fusion Genomic Features for SMURF1-TRIM4


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

Top

Fusion Protein Features for SMURF1-TRIM4


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr7:98741349/chr7:99507283)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneTRIM4chr7:98741348chr7:99507283ENST0000034906206212_253131475.0Coiled coilOntology_term=ECO:0000255
TgeneTRIM4chr7:98741348chr7:99507283ENST0000035424106212_253131295.0Coiled coilOntology_term=ECO:0000255
TgeneTRIM4chr7:98741348chr7:99507283ENST0000035594717212_253157501.0Coiled coilOntology_term=ECO:0000255
TgeneTRIM4chr7:98741349chr7:99507283ENST0000034906206212_253131475.0Coiled coilOntology_term=ECO:0000255
TgeneTRIM4chr7:98741349chr7:99507283ENST0000035424106212_253131295.0Coiled coilOntology_term=ECO:0000255
TgeneTRIM4chr7:98741349chr7:99507283ENST0000035594717212_253157501.0Coiled coilOntology_term=ECO:0000255
TgeneTRIM4chr7:98741348chr7:99507283ENST0000034906206288_500131475.0DomainB30.2/SPRY
TgeneTRIM4chr7:98741348chr7:99507283ENST0000035424106288_500131295.0DomainB30.2/SPRY
TgeneTRIM4chr7:98741348chr7:99507283ENST0000035594717288_500157501.0DomainB30.2/SPRY
TgeneTRIM4chr7:98741349chr7:99507283ENST0000034906206288_500131475.0DomainB30.2/SPRY
TgeneTRIM4chr7:98741349chr7:99507283ENST0000035424106288_500131295.0DomainB30.2/SPRY
TgeneTRIM4chr7:98741349chr7:99507283ENST0000035594717288_500157501.0DomainB30.2/SPRY

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneSMURF1chr7:98741348chr7:99507283ENST00000361125-1191_12018758.0DomainC2
HgeneSMURF1chr7:98741348chr7:99507283ENST00000361125-119234_26718758.0DomainWW 1
HgeneSMURF1chr7:98741348chr7:99507283ENST00000361125-119306_33918758.0DomainWW 2
HgeneSMURF1chr7:98741348chr7:99507283ENST00000361125-119420_75718758.0DomainHECT
HgeneSMURF1chr7:98741348chr7:99507283ENST00000361368-1181_12018732.0DomainC2
HgeneSMURF1chr7:98741348chr7:99507283ENST00000361368-118234_26718732.0DomainWW 1
HgeneSMURF1chr7:98741348chr7:99507283ENST00000361368-118306_33918732.0DomainWW 2
HgeneSMURF1chr7:98741348chr7:99507283ENST00000361368-118420_75718732.0DomainHECT
HgeneSMURF1chr7:98741349chr7:99507283ENST00000361125-1191_12018758.0DomainC2
HgeneSMURF1chr7:98741349chr7:99507283ENST00000361125-119234_26718758.0DomainWW 1
HgeneSMURF1chr7:98741349chr7:99507283ENST00000361125-119306_33918758.0DomainWW 2
HgeneSMURF1chr7:98741349chr7:99507283ENST00000361125-119420_75718758.0DomainHECT
HgeneSMURF1chr7:98741349chr7:99507283ENST00000361368-1181_12018732.0DomainC2
HgeneSMURF1chr7:98741349chr7:99507283ENST00000361368-118234_26718732.0DomainWW 1
HgeneSMURF1chr7:98741349chr7:99507283ENST00000361368-118306_33918732.0DomainWW 2
HgeneSMURF1chr7:98741349chr7:99507283ENST00000361368-118420_75718732.0DomainHECT
TgeneTRIM4chr7:98741348chr7:99507283ENST000003490620612_53131475.0Zinc fingerRING-type
TgeneTRIM4chr7:98741348chr7:99507283ENST000003490620682_123131475.0Zinc fingerB box-type
TgeneTRIM4chr7:98741348chr7:99507283ENST000003542410612_53131295.0Zinc fingerRING-type
TgeneTRIM4chr7:98741348chr7:99507283ENST000003542410682_123131295.0Zinc fingerB box-type
TgeneTRIM4chr7:98741348chr7:99507283ENST000003559471712_53157501.0Zinc fingerRING-type
TgeneTRIM4chr7:98741348chr7:99507283ENST000003559471782_123157501.0Zinc fingerB box-type
TgeneTRIM4chr7:98741349chr7:99507283ENST000003490620612_53131475.0Zinc fingerRING-type
TgeneTRIM4chr7:98741349chr7:99507283ENST000003490620682_123131475.0Zinc fingerB box-type
TgeneTRIM4chr7:98741349chr7:99507283ENST000003542410612_53131295.0Zinc fingerRING-type
TgeneTRIM4chr7:98741349chr7:99507283ENST000003542410682_123131295.0Zinc fingerB box-type
TgeneTRIM4chr7:98741349chr7:99507283ENST000003559471712_53157501.0Zinc fingerRING-type
TgeneTRIM4chr7:98741349chr7:99507283ENST000003559471782_123157501.0Zinc fingerB box-type


Top

Fusion Gene Sequence for SMURF1-TRIM4


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>84326_84326_1_SMURF1-TRIM4_SMURF1_chr7_98741348_ENST00000361125_TRIM4_chr7_99507283_ENST00000349062_length(transcript)=3157nt_BP=375nt
GGCAGCGGCGGAAGCGGCGAGGGCGGCGGGCGTCCGGCTCTGAGGTGGTGGAGGCGGCGGAGGCGGCGGCGGAGGCGGCGGCGGCTCGGG
ACTGGGCTCGGCTGGAAGCAGCGAGGGTCAGAGCGCCGCAGCAAGCGCCGATCTCCCGGCTCGACCATCCGCCTGCCGCCCGGACGCCTG
GGCCGCGGAGTTTGTGTCCCGGCTCGGACCCCGGCGCCCAGCCCGGAGCCGTAACCTTGAGGCGGCGGCGGCGGGGCCGGGCCGGGCCGG
GCTGGGGGGCGGTGGCGCTGGATCCGCGGCTGCCCGATCGTTGGCGGGAGATGTCGAACCCCGGGACACGCAGGAACGGCTCCAGCATCA
AGATCCGTCTGACAGGAGAAACTTCTTAAGTCTCAGCGTAATCTCGTGGCCAAGATGAAGAAAGTCATGCATTTACAGGATGTAGAAGTG
AAGAACGCCACACAGTGGAAGGATAAGATAAAGAGTCAGCGAATGAGAATCAGCACGGAGTTTTCAAAGCTGCACAACTTCCTGGTTGAA
GAAGAGGACCTGTTTCTTCAGAGATTGAACAAAGAAGAAGAAGAGACGAAGAAGAAGCTGAATGAGAACACGTTAAAACTCAATCAAACT
ATCGCTTCATTGAAGAAGCTCATCTTAGAGGTGGGGGAGAAGAGCCAGGCTCCCACCCTGGAGCTGCTTCAGAATCCAAAAGAAGTGTTG
ACCAGGAGTGAGATCCAGGATGTGAACTATTCTCTTGAAGCTGTAAAGGTGAAGACAGTGTGCCAGATACCATTGATGAAGGAAATGCTA
AAGCGATTCCAAGTGGCTGTAAACCTAGCTGAAGACACAGCTCATCCCAAACTCGTCTTCTCCCAGGAAGGGAGATACGTGAAAAATACA
GCATCAGCCAGTTCTTGGCCAGTGTTTTCTTCAGCATGGAACTACTTTGCTGGATGGAGGAATCCTCAGAAGACTGCTTTTGTAGAGAGA
TTTCAGCACTTACCCTGTGTTCTGGGAAAAAACGTTTTCACCTCAGGGAAACATTACTGGGAAGTTGAGAGTAGAGATAGTCTGGAGGTT
GCTGTTGGGGTGTGTCGGGAGGACGTCATGGGAATTACTGATCGTTCAAAAATGTCCCCAGATGTGGGCATCTGGGCGATTTATTGGAGT
GCTGCTGGCTATTGGCCCTTGATAGGCTTCCCTGGAACTCCCACCCAGCAAGAGCCAGCTCTCCACCGAGTGGGGGTTTACCTGGATCGT
GGGACTGGGAATGTCTCCTTCTACAGCGCTGTGGACGGAGTGCACCTGCACACCTTTTCTTGTTCTTCTGTCTCACGCCTCCGGCCATTT
TTTTGGTTGAGTCCATTAGCATCTTTAGTCATTCCACCAGTGACTGATAGGAAATGAGGCTTTTCTTCCCCTGACCAAAACTCCTTCCCT
GTAGTCCAGCTGAGGGACACACATCCCTGGGCCCTCTTCTGCCCTTCATGTCTCTATCCTGGATGGTCCATCTTCTGGGTCTCCCTAACG
GTACCGTTTGGTATCTGCCCTTTGTGTGCTTCACAAGAGGCAGTCCCATGGGAGGTGGGTCTGGCCAATGGAGATGGGACAGGAAATTTT
CCAAGACGCTTTTGGGAAATCTTTTTGTAGCTTTTAAAGAGATGTGCGGGGAAGACATATGGATGTTAGCAGCCATATTGGAACTGAGAA
CACAGGAATGGTGGAAAGGTAGAAGAAACAGAGTTTTTGTTGCCGTTGTGAAATTGTTGAAATTTCCTTCATGCCAAGCTTCTTGTTATA
TGAGATAATTACGCCCTTATTGTATAAGACAATTTTAGTTGTATTTGGTTACTTGCAGCCTGAAGTACCGTAACTGCACTAAAGGGACGT
AGTGTGAACATCCCGCAGTATAGGCTTAAGTCACTTTTGTGAAATTTGACAAAGGCATAGAATCTTTTTCTATCCAGTCAGGCATTGCCT
ATTCTTTCCAGTAACTACTGATTCCCCCACTTTTCTGTCTTAGAAAATTGTGGGAATCCCCCCTCACTCTGCCTATGTTGCACTCTCTCT
CTTCCCAACCATAACTCTGCCCTCAGCTATTAACTGTGCTGTGTATTTATCAAGTTGGTATGTTGTATGTACAGTGTTATTCATGTCATC
ATGAGAATGTTGAACGCTTGTTAAATATCTTTTGCTAGCCTCTTCATATGCTGTTGCATATGACTCTCATCACAACTCAGTGAGATGGAA
AGTCAAATCCTATTTGTACAAATGAGAAAACTGAACTCTTTAGAGTAACTAGCTCAGTATTGGCCAGCTGGTAAATGGCAGTGTTGGGAT
TAAAATCCAGTTCTTATCTACTCTCCCTTTATTCAGAAGCATTTATTGGATGTTGATCTTTGTTTCAGGTTTTGATTTTGTTACTTTTTT
ATACTGTGTATATTTTCCTCAGTCTACCCTTCTGCTCTAGATTGTCTGGACTCAGGAGATTGTGGCAGTTACTGGATAGTTATTTTTAAG
ATAATGATTGCTTTTCTCTGTTTATATAAGTCATGTGTACTTATTGTAGAAAGTTTGTAAGATGCAAAAAGTATAAAAATTAAAGTTATG
CACTACTAACATTTCAATATATTTTCTCCCAGATTTTCAGTAAAGACTTTCAGGCAGTGATTTAACGAGGATTTTATTTTAACTTATATT
TTAGTTTAAGGGGAACACGTGCAGGTTTGTTCTATAGATCAATTACATGTCACAGGGGTTTGGTGTACATATTATTTCATTACCCAGGTA
ATAAGCATAGTACCCAATAGATACTTTTTTGATACCCCACCCTCCTCCACCCTCTACCCTCAAGTAGTCCCTGGTGTCTGTTGTTCCCTT
TTTTGTGTCCATGGGTACTCAATGTTTAGCTCTCCCTTATACGTGAGAACATGTGATGTTTGGTTTTCTGTTCATGTGTTGGTTTGCTTA
GGGTAATGGCCTCCAGCTCCATCCATGTTGCTGCAAAGACATGATCTCATTCTTTTTTTATGGCTGCATAGTATTCCATGGTGTATATGT
ACTATGTTTTCTTTATCCAGTCTACTGTTGATGGGCATTTAGGTTGATTCCATGTCTTTGCTATTGTGAATAGTGCTGCAATGAATATAT

>84326_84326_1_SMURF1-TRIM4_SMURF1_chr7_98741348_ENST00000361125_TRIM4_chr7_99507283_ENST00000349062_length(amino acids)=330AA_BP=
MKKVMHLQDVEVKNATQWKDKIKSQRMRISTEFSKLHNFLVEEEDLFLQRLNKEEEETKKKLNENTLKLNQTIASLKKLILEVGEKSQAP
TLELLQNPKEVLTRSEIQDVNYSLEAVKVKTVCQIPLMKEMLKRFQVAVNLAEDTAHPKLVFSQEGRYVKNTASASSWPVFSSAWNYFAG
WRNPQKTAFVERFQHLPCVLGKNVFTSGKHYWEVESRDSLEVAVGVCREDVMGITDRSKMSPDVGIWAIYWSAAGYWPLIGFPGTPTQQE

--------------------------------------------------------------
>84326_84326_2_SMURF1-TRIM4_SMURF1_chr7_98741348_ENST00000361125_TRIM4_chr7_99507283_ENST00000354241_length(transcript)=1832nt_BP=375nt
GGCAGCGGCGGAAGCGGCGAGGGCGGCGGGCGTCCGGCTCTGAGGTGGTGGAGGCGGCGGAGGCGGCGGCGGAGGCGGCGGCGGCTCGGG
ACTGGGCTCGGCTGGAAGCAGCGAGGGTCAGAGCGCCGCAGCAAGCGCCGATCTCCCGGCTCGACCATCCGCCTGCCGCCCGGACGCCTG
GGCCGCGGAGTTTGTGTCCCGGCTCGGACCCCGGCGCCCAGCCCGGAGCCGTAACCTTGAGGCGGCGGCGGCGGGGCCGGGCCGGGCCGG
GCTGGGGGGCGGTGGCGCTGGATCCGCGGCTGCCCGATCGTTGGCGGGAGATGTCGAACCCCGGGACACGCAGGAACGGCTCCAGCATCA
AGATCCGTCTGACAGGAGAAACTTCTTAAGTCTCAGCGTAATCTCGTGGCCAAGATGAAGAAAGTCATGCATTTACAGGATGTAGAAGTG
AAGAACGCCACACAGTGGAAGGATAAGATAAAGAGTCAGCGAATGAGAATCAGCACGGAGTTTTCAAAGCTGCACAACTTCCTGGTTGAA
GAAGAGGACCTGTTTCTTCAGAGATTGAACAAAGAAGAAGAAGAGACGAAGAAGAAGCTGAATGAGAACACGTTAAAACTCAATCAAACT
ATCGCTTCATTGAAGAAGCTCATCTTAGAGGTGGGGGAGAAGAGCCAGGCTCCCACCCTGGAGCTGCTTCAGAATCCAAAAGAAGTGTTG
ACCAGGAGTGAGATCCAGGATGTGAACTATTCTCTTGAAGCTGTAAAGGTGAAGACAGTGTGCCAGATACCATTGATGAAGGAAATGCTA
AAGCGATTCCAAGCAACTAAAATAAAAACACAAAAACAAAACAGGCACAATATGTGAAACAACCGTTTTCAAAGCACCAGACGTCAGGCA
GTGAAGGACGGTGATTCCTGAGAAATGTGAAACAAATGAGGTCAGCCTATGATTGCCCTACCCTCTGCCTGAGGGAGTTTCCAGACCATG
TAAGGCTGAGGTAACTGAGGTAGAGCCAGGGAGACTTGCTGAGTTGAGGAATAGACCTGGGAGTTCACGGAGAACAAAGTAGTGAGAGTT
CGCAAAGTACTGGGCAGTATCCTGGAGCGGAGAGAGCCGGACACAGAGAGAACCCTCGCCATCTATGGAGGAGCTTCCTAGTTGTTTGGC
AGAGTTCTGATCAGCACATGCCTGTGAAAATCTACTCAAGGCTGGAGATAGAAGCTTCTAAAACGATTAGAGGGAACGGTTCCTGGTGCT
CACACAGGGCCAGGAACAGTGCCAGTTCCTATCAGCCACACCAGAAAACTCGTAGTTCACGGGCACTGAGTAGCGTACTCAGGAAAATCT
TGCCTCATTAGCAGAAAATATTTAGCCCTTGACTGGGTGCTGCTCCACACCCACCTTACAAATCATGAAAGCAAGACCCAAAGGGGTCAA
ACTCTTTCCAACTAACTTAACTGCATCCCAGGATAAAGCCCTAGAAAATTGGTAGAAATAAACAAAAAAAGAGCACCTAACAATATAAAT
TCACAATGTCTGGCATCCAGTCAAATATGCATGCAAAAAGATAGGAAAGCAGTGACCCATAATGGAGGAAAATAATCAACTGAAACTGAC
CTAGAATTGACACAGATGTTAGAATAAGCATGGAAGGACTTTAAAACATTTATTATGAGTGTATTCTGTAAAGAGGTACATAGAGACCAG
ATCAAAGTTTTAAAGATGAAAAATGTGATTAAGGCGAAGAATGCACTGGATGGGATTAATAGTTGATTAAATATTACAAAAGAAAAAATT

>84326_84326_2_SMURF1-TRIM4_SMURF1_chr7_98741348_ENST00000361125_TRIM4_chr7_99507283_ENST00000354241_length(amino acids)=150AA_BP=
MKKVMHLQDVEVKNATQWKDKIKSQRMRISTEFSKLHNFLVEEEDLFLQRLNKEEEETKKKLNENTLKLNQTIASLKKLILEVGEKSQAP

--------------------------------------------------------------
>84326_84326_3_SMURF1-TRIM4_SMURF1_chr7_98741348_ENST00000361125_TRIM4_chr7_99507283_ENST00000355947_length(transcript)=3157nt_BP=375nt
GGCAGCGGCGGAAGCGGCGAGGGCGGCGGGCGTCCGGCTCTGAGGTGGTGGAGGCGGCGGAGGCGGCGGCGGAGGCGGCGGCGGCTCGGG
ACTGGGCTCGGCTGGAAGCAGCGAGGGTCAGAGCGCCGCAGCAAGCGCCGATCTCCCGGCTCGACCATCCGCCTGCCGCCCGGACGCCTG
GGCCGCGGAGTTTGTGTCCCGGCTCGGACCCCGGCGCCCAGCCCGGAGCCGTAACCTTGAGGCGGCGGCGGCGGGGCCGGGCCGGGCCGG
GCTGGGGGGCGGTGGCGCTGGATCCGCGGCTGCCCGATCGTTGGCGGGAGATGTCGAACCCCGGGACACGCAGGAACGGCTCCAGCATCA
AGATCCGTCTGACAGGAGAAACTTCTTAAGTCTCAGCGTAATCTCGTGGCCAAGATGAAGAAAGTCATGCATTTACAGGATGTAGAAGTG
AAGAACGCCACACAGTGGAAGGATAAGATAAAGAGTCAGCGAATGAGAATCAGCACGGAGTTTTCAAAGCTGCACAACTTCCTGGTTGAA
GAAGAGGACCTGTTTCTTCAGAGATTGAACAAAGAAGAAGAAGAGACGAAGAAGAAGCTGAATGAGAACACGTTAAAACTCAATCAAACT
ATCGCTTCATTGAAGAAGCTCATCTTAGAGGTGGGGGAGAAGAGCCAGGCTCCCACCCTGGAGCTGCTTCAGAATCCAAAAGAAGTGTTG
ACCAGGAGTGAGATCCAGGATGTGAACTATTCTCTTGAAGCTGTAAAGGTGAAGACAGTGTGCCAGATACCATTGATGAAGGAAATGCTA
AAGCGATTCCAAGTGGCTGTAAACCTAGCTGAAGACACAGCTCATCCCAAACTCGTCTTCTCCCAGGAAGGGAGATACGTGAAAAATACA
GCATCAGCCAGTTCTTGGCCAGTGTTTTCTTCAGCATGGAACTACTTTGCTGGATGGAGGAATCCTCAGAAGACTGCTTTTGTAGAGAGA
TTTCAGCACTTACCCTGTGTTCTGGGAAAAAACGTTTTCACCTCAGGGAAACATTACTGGGAAGTTGAGAGTAGAGATAGTCTGGAGGTT
GCTGTTGGGGTGTGTCGGGAGGACGTCATGGGAATTACTGATCGTTCAAAAATGTCCCCAGATGTGGGCATCTGGGCGATTTATTGGAGT
GCTGCTGGCTATTGGCCCTTGATAGGCTTCCCTGGAACTCCCACCCAGCAAGAGCCAGCTCTCCACCGAGTGGGGGTTTACCTGGATCGT
GGGACTGGGAATGTCTCCTTCTACAGCGCTGTGGACGGAGTGCACCTGCACACCTTTTCTTGTTCTTCTGTCTCACGCCTCCGGCCATTT
TTTTGGTTGAGTCCATTAGCATCTTTAGTCATTCCACCAGTGACTGATAGGAAATGAGGCTTTTCTTCCCCTGACCAAAACTCCTTCCCT
GTAGTCCAGCTGAGGGACACACATCCCTGGGCCCTCTTCTGCCCTTCATGTCTCTATCCTGGATGGTCCATCTTCTGGGTCTCCCTAACG
GTACCGTTTGGTATCTGCCCTTTGTGTGCTTCACAAGAGGCAGTCCCATGGGAGGTGGGTCTGGCCAATGGAGATGGGACAGGAAATTTT
CCAAGACGCTTTTGGGAAATCTTTTTGTAGCTTTTAAAGAGATGTGCGGGGAAGACATATGGATGTTAGCAGCCATATTGGAACTGAGAA
CACAGGAATGGTGGAAAGGTAGAAGAAACAGAGTTTTTGTTGCCGTTGTGAAATTGTTGAAATTTCCTTCATGCCAAGCTTCTTGTTATA
TGAGATAATTACGCCCTTATTGTATAAGACAATTTTAGTTGTATTTGGTTACTTGCAGCCTGAAGTACCGTAACTGCACTAAAGGGACGT
AGTGTGAACATCCCGCAGTATAGGCTTAAGTCACTTTTGTGAAATTTGACAAAGGCATAGAATCTTTTTCTATCCAGTCAGGCATTGCCT
ATTCTTTCCAGTAACTACTGATTCCCCCACTTTTCTGTCTTAGAAAATTGTGGGAATCCCCCCTCACTCTGCCTATGTTGCACTCTCTCT
CTTCCCAACCATAACTCTGCCCTCAGCTATTAACTGTGCTGTGTATTTATCAAGTTGGTATGTTGTATGTACAGTGTTATTCATGTCATC
ATGAGAATGTTGAACGCTTGTTAAATATCTTTTGCTAGCCTCTTCATATGCTGTTGCATATGACTCTCATCACAACTCAGTGAGATGGAA
AGTCAAATCCTATTTGTACAAATGAGAAAACTGAACTCTTTAGAGTAACTAGCTCAGTATTGGCCAGCTGGTAAATGGCAGTGTTGGGAT
TAAAATCCAGTTCTTATCTACTCTCCCTTTATTCAGAAGCATTTATTGGATGTTGATCTTTGTTTCAGGTTTTGATTTTGTTACTTTTTT
ATACTGTGTATATTTTCCTCAGTCTACCCTTCTGCTCTAGATTGTCTGGACTCAGGAGATTGTGGCAGTTACTGGATAGTTATTTTTAAG
ATAATGATTGCTTTTCTCTGTTTATATAAGTCATGTGTACTTATTGTAGAAAGTTTGTAAGATGCAAAAAGTATAAAAATTAAAGTTATG
CACTACTAACATTTCAATATATTTTCTCCCAGATTTTCAGTAAAGACTTTCAGGCAGTGATTTAACGAGGATTTTATTTTAACTTATATT
TTAGTTTAAGGGGAACACGTGCAGGTTTGTTCTATAGATCAATTACATGTCACAGGGGTTTGGTGTACATATTATTTCATTACCCAGGTA
ATAAGCATAGTACCCAATAGATACTTTTTTGATACCCCACCCTCCTCCACCCTCTACCCTCAAGTAGTCCCTGGTGTCTGTTGTTCCCTT
TTTTGTGTCCATGGGTACTCAATGTTTAGCTCTCCCTTATACGTGAGAACATGTGATGTTTGGTTTTCTGTTCATGTGTTGGTTTGCTTA
GGGTAATGGCCTCCAGCTCCATCCATGTTGCTGCAAAGACATGATCTCATTCTTTTTTTATGGCTGCATAGTATTCCATGGTGTATATGT
ACTATGTTTTCTTTATCCAGTCTACTGTTGATGGGCATTTAGGTTGATTCCATGTCTTTGCTATTGTGAATAGTGCTGCAATGAATATAT

>84326_84326_3_SMURF1-TRIM4_SMURF1_chr7_98741348_ENST00000361125_TRIM4_chr7_99507283_ENST00000355947_length(amino acids)=330AA_BP=
MKKVMHLQDVEVKNATQWKDKIKSQRMRISTEFSKLHNFLVEEEDLFLQRLNKEEEETKKKLNENTLKLNQTIASLKKLILEVGEKSQAP
TLELLQNPKEVLTRSEIQDVNYSLEAVKVKTVCQIPLMKEMLKRFQVAVNLAEDTAHPKLVFSQEGRYVKNTASASSWPVFSSAWNYFAG
WRNPQKTAFVERFQHLPCVLGKNVFTSGKHYWEVESRDSLEVAVGVCREDVMGITDRSKMSPDVGIWAIYWSAAGYWPLIGFPGTPTQQE

--------------------------------------------------------------
>84326_84326_4_SMURF1-TRIM4_SMURF1_chr7_98741348_ENST00000361368_TRIM4_chr7_99507283_ENST00000349062_length(transcript)=3076nt_BP=294nt
CGGCTCGGGACTGGGCTCGGCTGGAAGCAGCGAGGGTCAGAGCGCCGCAGCAAGCGCCGATCTCCCGGCTCGACCATCCGCCTGCCGCCC
GGACGCCTGGGCCGCGGAGTTTGTGTCCCGGCTCGGACCCCGGCGCCCAGCCCGGAGCCGTAACCTTGAGGCGGCGGCGGCGGGGCCGGG
CCGGGCCGGGCTGGGGGGCGGTGGCGCTGGATCCGCGGCTGCCCGATCGTTGGCGGGAGATGTCGAACCCCGGGACACGCAGGAACGGCT
CCAGCATCAAGATCCGTCTGACAGGAGAAACTTCTTAAGTCTCAGCGTAATCTCGTGGCCAAGATGAAGAAAGTCATGCATTTACAGGAT
GTAGAAGTGAAGAACGCCACACAGTGGAAGGATAAGATAAAGAGTCAGCGAATGAGAATCAGCACGGAGTTTTCAAAGCTGCACAACTTC
CTGGTTGAAGAAGAGGACCTGTTTCTTCAGAGATTGAACAAAGAAGAAGAAGAGACGAAGAAGAAGCTGAATGAGAACACGTTAAAACTC
AATCAAACTATCGCTTCATTGAAGAAGCTCATCTTAGAGGTGGGGGAGAAGAGCCAGGCTCCCACCCTGGAGCTGCTTCAGAATCCAAAA
GAAGTGTTGACCAGGAGTGAGATCCAGGATGTGAACTATTCTCTTGAAGCTGTAAAGGTGAAGACAGTGTGCCAGATACCATTGATGAAG
GAAATGCTAAAGCGATTCCAAGTGGCTGTAAACCTAGCTGAAGACACAGCTCATCCCAAACTCGTCTTCTCCCAGGAAGGGAGATACGTG
AAAAATACAGCATCAGCCAGTTCTTGGCCAGTGTTTTCTTCAGCATGGAACTACTTTGCTGGATGGAGGAATCCTCAGAAGACTGCTTTT
GTAGAGAGATTTCAGCACTTACCCTGTGTTCTGGGAAAAAACGTTTTCACCTCAGGGAAACATTACTGGGAAGTTGAGAGTAGAGATAGT
CTGGAGGTTGCTGTTGGGGTGTGTCGGGAGGACGTCATGGGAATTACTGATCGTTCAAAAATGTCCCCAGATGTGGGCATCTGGGCGATT
TATTGGAGTGCTGCTGGCTATTGGCCCTTGATAGGCTTCCCTGGAACTCCCACCCAGCAAGAGCCAGCTCTCCACCGAGTGGGGGTTTAC
CTGGATCGTGGGACTGGGAATGTCTCCTTCTACAGCGCTGTGGACGGAGTGCACCTGCACACCTTTTCTTGTTCTTCTGTCTCACGCCTC
CGGCCATTTTTTTGGTTGAGTCCATTAGCATCTTTAGTCATTCCACCAGTGACTGATAGGAAATGAGGCTTTTCTTCCCCTGACCAAAAC
TCCTTCCCTGTAGTCCAGCTGAGGGACACACATCCCTGGGCCCTCTTCTGCCCTTCATGTCTCTATCCTGGATGGTCCATCTTCTGGGTC
TCCCTAACGGTACCGTTTGGTATCTGCCCTTTGTGTGCTTCACAAGAGGCAGTCCCATGGGAGGTGGGTCTGGCCAATGGAGATGGGACA
GGAAATTTTCCAAGACGCTTTTGGGAAATCTTTTTGTAGCTTTTAAAGAGATGTGCGGGGAAGACATATGGATGTTAGCAGCCATATTGG
AACTGAGAACACAGGAATGGTGGAAAGGTAGAAGAAACAGAGTTTTTGTTGCCGTTGTGAAATTGTTGAAATTTCCTTCATGCCAAGCTT
CTTGTTATATGAGATAATTACGCCCTTATTGTATAAGACAATTTTAGTTGTATTTGGTTACTTGCAGCCTGAAGTACCGTAACTGCACTA
AAGGGACGTAGTGTGAACATCCCGCAGTATAGGCTTAAGTCACTTTTGTGAAATTTGACAAAGGCATAGAATCTTTTTCTATCCAGTCAG
GCATTGCCTATTCTTTCCAGTAACTACTGATTCCCCCACTTTTCTGTCTTAGAAAATTGTGGGAATCCCCCCTCACTCTGCCTATGTTGC
ACTCTCTCTCTTCCCAACCATAACTCTGCCCTCAGCTATTAACTGTGCTGTGTATTTATCAAGTTGGTATGTTGTATGTACAGTGTTATT
CATGTCATCATGAGAATGTTGAACGCTTGTTAAATATCTTTTGCTAGCCTCTTCATATGCTGTTGCATATGACTCTCATCACAACTCAGT
GAGATGGAAAGTCAAATCCTATTTGTACAAATGAGAAAACTGAACTCTTTAGAGTAACTAGCTCAGTATTGGCCAGCTGGTAAATGGCAG
TGTTGGGATTAAAATCCAGTTCTTATCTACTCTCCCTTTATTCAGAAGCATTTATTGGATGTTGATCTTTGTTTCAGGTTTTGATTTTGT
TACTTTTTTATACTGTGTATATTTTCCTCAGTCTACCCTTCTGCTCTAGATTGTCTGGACTCAGGAGATTGTGGCAGTTACTGGATAGTT
ATTTTTAAGATAATGATTGCTTTTCTCTGTTTATATAAGTCATGTGTACTTATTGTAGAAAGTTTGTAAGATGCAAAAAGTATAAAAATT
AAAGTTATGCACTACTAACATTTCAATATATTTTCTCCCAGATTTTCAGTAAAGACTTTCAGGCAGTGATTTAACGAGGATTTTATTTTA
ACTTATATTTTAGTTTAAGGGGAACACGTGCAGGTTTGTTCTATAGATCAATTACATGTCACAGGGGTTTGGTGTACATATTATTTCATT
ACCCAGGTAATAAGCATAGTACCCAATAGATACTTTTTTGATACCCCACCCTCCTCCACCCTCTACCCTCAAGTAGTCCCTGGTGTCTGT
TGTTCCCTTTTTTGTGTCCATGGGTACTCAATGTTTAGCTCTCCCTTATACGTGAGAACATGTGATGTTTGGTTTTCTGTTCATGTGTTG
GTTTGCTTAGGGTAATGGCCTCCAGCTCCATCCATGTTGCTGCAAAGACATGATCTCATTCTTTTTTTATGGCTGCATAGTATTCCATGG
TGTATATGTACTATGTTTTCTTTATCCAGTCTACTGTTGATGGGCATTTAGGTTGATTCCATGTCTTTGCTATTGTGAATAGTGCTGCAA

>84326_84326_4_SMURF1-TRIM4_SMURF1_chr7_98741348_ENST00000361368_TRIM4_chr7_99507283_ENST00000349062_length(amino acids)=330AA_BP=
MKKVMHLQDVEVKNATQWKDKIKSQRMRISTEFSKLHNFLVEEEDLFLQRLNKEEEETKKKLNENTLKLNQTIASLKKLILEVGEKSQAP
TLELLQNPKEVLTRSEIQDVNYSLEAVKVKTVCQIPLMKEMLKRFQVAVNLAEDTAHPKLVFSQEGRYVKNTASASSWPVFSSAWNYFAG
WRNPQKTAFVERFQHLPCVLGKNVFTSGKHYWEVESRDSLEVAVGVCREDVMGITDRSKMSPDVGIWAIYWSAAGYWPLIGFPGTPTQQE

--------------------------------------------------------------
>84326_84326_5_SMURF1-TRIM4_SMURF1_chr7_98741348_ENST00000361368_TRIM4_chr7_99507283_ENST00000354241_length(transcript)=1751nt_BP=294nt
CGGCTCGGGACTGGGCTCGGCTGGAAGCAGCGAGGGTCAGAGCGCCGCAGCAAGCGCCGATCTCCCGGCTCGACCATCCGCCTGCCGCCC
GGACGCCTGGGCCGCGGAGTTTGTGTCCCGGCTCGGACCCCGGCGCCCAGCCCGGAGCCGTAACCTTGAGGCGGCGGCGGCGGGGCCGGG
CCGGGCCGGGCTGGGGGGCGGTGGCGCTGGATCCGCGGCTGCCCGATCGTTGGCGGGAGATGTCGAACCCCGGGACACGCAGGAACGGCT
CCAGCATCAAGATCCGTCTGACAGGAGAAACTTCTTAAGTCTCAGCGTAATCTCGTGGCCAAGATGAAGAAAGTCATGCATTTACAGGAT
GTAGAAGTGAAGAACGCCACACAGTGGAAGGATAAGATAAAGAGTCAGCGAATGAGAATCAGCACGGAGTTTTCAAAGCTGCACAACTTC
CTGGTTGAAGAAGAGGACCTGTTTCTTCAGAGATTGAACAAAGAAGAAGAAGAGACGAAGAAGAAGCTGAATGAGAACACGTTAAAACTC
AATCAAACTATCGCTTCATTGAAGAAGCTCATCTTAGAGGTGGGGGAGAAGAGCCAGGCTCCCACCCTGGAGCTGCTTCAGAATCCAAAA
GAAGTGTTGACCAGGAGTGAGATCCAGGATGTGAACTATTCTCTTGAAGCTGTAAAGGTGAAGACAGTGTGCCAGATACCATTGATGAAG
GAAATGCTAAAGCGATTCCAAGCAACTAAAATAAAAACACAAAAACAAAACAGGCACAATATGTGAAACAACCGTTTTCAAAGCACCAGA
CGTCAGGCAGTGAAGGACGGTGATTCCTGAGAAATGTGAAACAAATGAGGTCAGCCTATGATTGCCCTACCCTCTGCCTGAGGGAGTTTC
CAGACCATGTAAGGCTGAGGTAACTGAGGTAGAGCCAGGGAGACTTGCTGAGTTGAGGAATAGACCTGGGAGTTCACGGAGAACAAAGTA
GTGAGAGTTCGCAAAGTACTGGGCAGTATCCTGGAGCGGAGAGAGCCGGACACAGAGAGAACCCTCGCCATCTATGGAGGAGCTTCCTAG
TTGTTTGGCAGAGTTCTGATCAGCACATGCCTGTGAAAATCTACTCAAGGCTGGAGATAGAAGCTTCTAAAACGATTAGAGGGAACGGTT
CCTGGTGCTCACACAGGGCCAGGAACAGTGCCAGTTCCTATCAGCCACACCAGAAAACTCGTAGTTCACGGGCACTGAGTAGCGTACTCA
GGAAAATCTTGCCTCATTAGCAGAAAATATTTAGCCCTTGACTGGGTGCTGCTCCACACCCACCTTACAAATCATGAAAGCAAGACCCAA
AGGGGTCAAACTCTTTCCAACTAACTTAACTGCATCCCAGGATAAAGCCCTAGAAAATTGGTAGAAATAAACAAAAAAAGAGCACCTAAC
AATATAAATTCACAATGTCTGGCATCCAGTCAAATATGCATGCAAAAAGATAGGAAAGCAGTGACCCATAATGGAGGAAAATAATCAACT
GAAACTGACCTAGAATTGACACAGATGTTAGAATAAGCATGGAAGGACTTTAAAACATTTATTATGAGTGTATTCTGTAAAGAGGTACAT
AGAGACCAGATCAAAGTTTTAAAGATGAAAAATGTGATTAAGGCGAAGAATGCACTGGATGGGATTAATAGTTGATTAAATATTACAAAA

>84326_84326_5_SMURF1-TRIM4_SMURF1_chr7_98741348_ENST00000361368_TRIM4_chr7_99507283_ENST00000354241_length(amino acids)=150AA_BP=
MKKVMHLQDVEVKNATQWKDKIKSQRMRISTEFSKLHNFLVEEEDLFLQRLNKEEEETKKKLNENTLKLNQTIASLKKLILEVGEKSQAP

--------------------------------------------------------------
>84326_84326_6_SMURF1-TRIM4_SMURF1_chr7_98741348_ENST00000361368_TRIM4_chr7_99507283_ENST00000355947_length(transcript)=3076nt_BP=294nt
CGGCTCGGGACTGGGCTCGGCTGGAAGCAGCGAGGGTCAGAGCGCCGCAGCAAGCGCCGATCTCCCGGCTCGACCATCCGCCTGCCGCCC
GGACGCCTGGGCCGCGGAGTTTGTGTCCCGGCTCGGACCCCGGCGCCCAGCCCGGAGCCGTAACCTTGAGGCGGCGGCGGCGGGGCCGGG
CCGGGCCGGGCTGGGGGGCGGTGGCGCTGGATCCGCGGCTGCCCGATCGTTGGCGGGAGATGTCGAACCCCGGGACACGCAGGAACGGCT
CCAGCATCAAGATCCGTCTGACAGGAGAAACTTCTTAAGTCTCAGCGTAATCTCGTGGCCAAGATGAAGAAAGTCATGCATTTACAGGAT
GTAGAAGTGAAGAACGCCACACAGTGGAAGGATAAGATAAAGAGTCAGCGAATGAGAATCAGCACGGAGTTTTCAAAGCTGCACAACTTC
CTGGTTGAAGAAGAGGACCTGTTTCTTCAGAGATTGAACAAAGAAGAAGAAGAGACGAAGAAGAAGCTGAATGAGAACACGTTAAAACTC
AATCAAACTATCGCTTCATTGAAGAAGCTCATCTTAGAGGTGGGGGAGAAGAGCCAGGCTCCCACCCTGGAGCTGCTTCAGAATCCAAAA
GAAGTGTTGACCAGGAGTGAGATCCAGGATGTGAACTATTCTCTTGAAGCTGTAAAGGTGAAGACAGTGTGCCAGATACCATTGATGAAG
GAAATGCTAAAGCGATTCCAAGTGGCTGTAAACCTAGCTGAAGACACAGCTCATCCCAAACTCGTCTTCTCCCAGGAAGGGAGATACGTG
AAAAATACAGCATCAGCCAGTTCTTGGCCAGTGTTTTCTTCAGCATGGAACTACTTTGCTGGATGGAGGAATCCTCAGAAGACTGCTTTT
GTAGAGAGATTTCAGCACTTACCCTGTGTTCTGGGAAAAAACGTTTTCACCTCAGGGAAACATTACTGGGAAGTTGAGAGTAGAGATAGT
CTGGAGGTTGCTGTTGGGGTGTGTCGGGAGGACGTCATGGGAATTACTGATCGTTCAAAAATGTCCCCAGATGTGGGCATCTGGGCGATT
TATTGGAGTGCTGCTGGCTATTGGCCCTTGATAGGCTTCCCTGGAACTCCCACCCAGCAAGAGCCAGCTCTCCACCGAGTGGGGGTTTAC
CTGGATCGTGGGACTGGGAATGTCTCCTTCTACAGCGCTGTGGACGGAGTGCACCTGCACACCTTTTCTTGTTCTTCTGTCTCACGCCTC
CGGCCATTTTTTTGGTTGAGTCCATTAGCATCTTTAGTCATTCCACCAGTGACTGATAGGAAATGAGGCTTTTCTTCCCCTGACCAAAAC
TCCTTCCCTGTAGTCCAGCTGAGGGACACACATCCCTGGGCCCTCTTCTGCCCTTCATGTCTCTATCCTGGATGGTCCATCTTCTGGGTC
TCCCTAACGGTACCGTTTGGTATCTGCCCTTTGTGTGCTTCACAAGAGGCAGTCCCATGGGAGGTGGGTCTGGCCAATGGAGATGGGACA
GGAAATTTTCCAAGACGCTTTTGGGAAATCTTTTTGTAGCTTTTAAAGAGATGTGCGGGGAAGACATATGGATGTTAGCAGCCATATTGG
AACTGAGAACACAGGAATGGTGGAAAGGTAGAAGAAACAGAGTTTTTGTTGCCGTTGTGAAATTGTTGAAATTTCCTTCATGCCAAGCTT
CTTGTTATATGAGATAATTACGCCCTTATTGTATAAGACAATTTTAGTTGTATTTGGTTACTTGCAGCCTGAAGTACCGTAACTGCACTA
AAGGGACGTAGTGTGAACATCCCGCAGTATAGGCTTAAGTCACTTTTGTGAAATTTGACAAAGGCATAGAATCTTTTTCTATCCAGTCAG
GCATTGCCTATTCTTTCCAGTAACTACTGATTCCCCCACTTTTCTGTCTTAGAAAATTGTGGGAATCCCCCCTCACTCTGCCTATGTTGC
ACTCTCTCTCTTCCCAACCATAACTCTGCCCTCAGCTATTAACTGTGCTGTGTATTTATCAAGTTGGTATGTTGTATGTACAGTGTTATT
CATGTCATCATGAGAATGTTGAACGCTTGTTAAATATCTTTTGCTAGCCTCTTCATATGCTGTTGCATATGACTCTCATCACAACTCAGT
GAGATGGAAAGTCAAATCCTATTTGTACAAATGAGAAAACTGAACTCTTTAGAGTAACTAGCTCAGTATTGGCCAGCTGGTAAATGGCAG
TGTTGGGATTAAAATCCAGTTCTTATCTACTCTCCCTTTATTCAGAAGCATTTATTGGATGTTGATCTTTGTTTCAGGTTTTGATTTTGT
TACTTTTTTATACTGTGTATATTTTCCTCAGTCTACCCTTCTGCTCTAGATTGTCTGGACTCAGGAGATTGTGGCAGTTACTGGATAGTT
ATTTTTAAGATAATGATTGCTTTTCTCTGTTTATATAAGTCATGTGTACTTATTGTAGAAAGTTTGTAAGATGCAAAAAGTATAAAAATT
AAAGTTATGCACTACTAACATTTCAATATATTTTCTCCCAGATTTTCAGTAAAGACTTTCAGGCAGTGATTTAACGAGGATTTTATTTTA
ACTTATATTTTAGTTTAAGGGGAACACGTGCAGGTTTGTTCTATAGATCAATTACATGTCACAGGGGTTTGGTGTACATATTATTTCATT
ACCCAGGTAATAAGCATAGTACCCAATAGATACTTTTTTGATACCCCACCCTCCTCCACCCTCTACCCTCAAGTAGTCCCTGGTGTCTGT
TGTTCCCTTTTTTGTGTCCATGGGTACTCAATGTTTAGCTCTCCCTTATACGTGAGAACATGTGATGTTTGGTTTTCTGTTCATGTGTTG
GTTTGCTTAGGGTAATGGCCTCCAGCTCCATCCATGTTGCTGCAAAGACATGATCTCATTCTTTTTTTATGGCTGCATAGTATTCCATGG
TGTATATGTACTATGTTTTCTTTATCCAGTCTACTGTTGATGGGCATTTAGGTTGATTCCATGTCTTTGCTATTGTGAATAGTGCTGCAA

>84326_84326_6_SMURF1-TRIM4_SMURF1_chr7_98741348_ENST00000361368_TRIM4_chr7_99507283_ENST00000355947_length(amino acids)=330AA_BP=
MKKVMHLQDVEVKNATQWKDKIKSQRMRISTEFSKLHNFLVEEEDLFLQRLNKEEEETKKKLNENTLKLNQTIASLKKLILEVGEKSQAP
TLELLQNPKEVLTRSEIQDVNYSLEAVKVKTVCQIPLMKEMLKRFQVAVNLAEDTAHPKLVFSQEGRYVKNTASASSWPVFSSAWNYFAG
WRNPQKTAFVERFQHLPCVLGKNVFTSGKHYWEVESRDSLEVAVGVCREDVMGITDRSKMSPDVGIWAIYWSAAGYWPLIGFPGTPTQQE

--------------------------------------------------------------
>84326_84326_7_SMURF1-TRIM4_SMURF1_chr7_98741349_ENST00000361125_TRIM4_chr7_99507283_ENST00000349062_length(transcript)=3157nt_BP=375nt
GGCAGCGGCGGAAGCGGCGAGGGCGGCGGGCGTCCGGCTCTGAGGTGGTGGAGGCGGCGGAGGCGGCGGCGGAGGCGGCGGCGGCTCGGG
ACTGGGCTCGGCTGGAAGCAGCGAGGGTCAGAGCGCCGCAGCAAGCGCCGATCTCCCGGCTCGACCATCCGCCTGCCGCCCGGACGCCTG
GGCCGCGGAGTTTGTGTCCCGGCTCGGACCCCGGCGCCCAGCCCGGAGCCGTAACCTTGAGGCGGCGGCGGCGGGGCCGGGCCGGGCCGG
GCTGGGGGGCGGTGGCGCTGGATCCGCGGCTGCCCGATCGTTGGCGGGAGATGTCGAACCCCGGGACACGCAGGAACGGCTCCAGCATCA
AGATCCGTCTGACAGGAGAAACTTCTTAAGTCTCAGCGTAATCTCGTGGCCAAGATGAAGAAAGTCATGCATTTACAGGATGTAGAAGTG
AAGAACGCCACACAGTGGAAGGATAAGATAAAGAGTCAGCGAATGAGAATCAGCACGGAGTTTTCAAAGCTGCACAACTTCCTGGTTGAA
GAAGAGGACCTGTTTCTTCAGAGATTGAACAAAGAAGAAGAAGAGACGAAGAAGAAGCTGAATGAGAACACGTTAAAACTCAATCAAACT
ATCGCTTCATTGAAGAAGCTCATCTTAGAGGTGGGGGAGAAGAGCCAGGCTCCCACCCTGGAGCTGCTTCAGAATCCAAAAGAAGTGTTG
ACCAGGAGTGAGATCCAGGATGTGAACTATTCTCTTGAAGCTGTAAAGGTGAAGACAGTGTGCCAGATACCATTGATGAAGGAAATGCTA
AAGCGATTCCAAGTGGCTGTAAACCTAGCTGAAGACACAGCTCATCCCAAACTCGTCTTCTCCCAGGAAGGGAGATACGTGAAAAATACA
GCATCAGCCAGTTCTTGGCCAGTGTTTTCTTCAGCATGGAACTACTTTGCTGGATGGAGGAATCCTCAGAAGACTGCTTTTGTAGAGAGA
TTTCAGCACTTACCCTGTGTTCTGGGAAAAAACGTTTTCACCTCAGGGAAACATTACTGGGAAGTTGAGAGTAGAGATAGTCTGGAGGTT
GCTGTTGGGGTGTGTCGGGAGGACGTCATGGGAATTACTGATCGTTCAAAAATGTCCCCAGATGTGGGCATCTGGGCGATTTATTGGAGT
GCTGCTGGCTATTGGCCCTTGATAGGCTTCCCTGGAACTCCCACCCAGCAAGAGCCAGCTCTCCACCGAGTGGGGGTTTACCTGGATCGT
GGGACTGGGAATGTCTCCTTCTACAGCGCTGTGGACGGAGTGCACCTGCACACCTTTTCTTGTTCTTCTGTCTCACGCCTCCGGCCATTT
TTTTGGTTGAGTCCATTAGCATCTTTAGTCATTCCACCAGTGACTGATAGGAAATGAGGCTTTTCTTCCCCTGACCAAAACTCCTTCCCT
GTAGTCCAGCTGAGGGACACACATCCCTGGGCCCTCTTCTGCCCTTCATGTCTCTATCCTGGATGGTCCATCTTCTGGGTCTCCCTAACG
GTACCGTTTGGTATCTGCCCTTTGTGTGCTTCACAAGAGGCAGTCCCATGGGAGGTGGGTCTGGCCAATGGAGATGGGACAGGAAATTTT
CCAAGACGCTTTTGGGAAATCTTTTTGTAGCTTTTAAAGAGATGTGCGGGGAAGACATATGGATGTTAGCAGCCATATTGGAACTGAGAA
CACAGGAATGGTGGAAAGGTAGAAGAAACAGAGTTTTTGTTGCCGTTGTGAAATTGTTGAAATTTCCTTCATGCCAAGCTTCTTGTTATA
TGAGATAATTACGCCCTTATTGTATAAGACAATTTTAGTTGTATTTGGTTACTTGCAGCCTGAAGTACCGTAACTGCACTAAAGGGACGT
AGTGTGAACATCCCGCAGTATAGGCTTAAGTCACTTTTGTGAAATTTGACAAAGGCATAGAATCTTTTTCTATCCAGTCAGGCATTGCCT
ATTCTTTCCAGTAACTACTGATTCCCCCACTTTTCTGTCTTAGAAAATTGTGGGAATCCCCCCTCACTCTGCCTATGTTGCACTCTCTCT
CTTCCCAACCATAACTCTGCCCTCAGCTATTAACTGTGCTGTGTATTTATCAAGTTGGTATGTTGTATGTACAGTGTTATTCATGTCATC
ATGAGAATGTTGAACGCTTGTTAAATATCTTTTGCTAGCCTCTTCATATGCTGTTGCATATGACTCTCATCACAACTCAGTGAGATGGAA
AGTCAAATCCTATTTGTACAAATGAGAAAACTGAACTCTTTAGAGTAACTAGCTCAGTATTGGCCAGCTGGTAAATGGCAGTGTTGGGAT
TAAAATCCAGTTCTTATCTACTCTCCCTTTATTCAGAAGCATTTATTGGATGTTGATCTTTGTTTCAGGTTTTGATTTTGTTACTTTTTT
ATACTGTGTATATTTTCCTCAGTCTACCCTTCTGCTCTAGATTGTCTGGACTCAGGAGATTGTGGCAGTTACTGGATAGTTATTTTTAAG
ATAATGATTGCTTTTCTCTGTTTATATAAGTCATGTGTACTTATTGTAGAAAGTTTGTAAGATGCAAAAAGTATAAAAATTAAAGTTATG
CACTACTAACATTTCAATATATTTTCTCCCAGATTTTCAGTAAAGACTTTCAGGCAGTGATTTAACGAGGATTTTATTTTAACTTATATT
TTAGTTTAAGGGGAACACGTGCAGGTTTGTTCTATAGATCAATTACATGTCACAGGGGTTTGGTGTACATATTATTTCATTACCCAGGTA
ATAAGCATAGTACCCAATAGATACTTTTTTGATACCCCACCCTCCTCCACCCTCTACCCTCAAGTAGTCCCTGGTGTCTGTTGTTCCCTT
TTTTGTGTCCATGGGTACTCAATGTTTAGCTCTCCCTTATACGTGAGAACATGTGATGTTTGGTTTTCTGTTCATGTGTTGGTTTGCTTA
GGGTAATGGCCTCCAGCTCCATCCATGTTGCTGCAAAGACATGATCTCATTCTTTTTTTATGGCTGCATAGTATTCCATGGTGTATATGT
ACTATGTTTTCTTTATCCAGTCTACTGTTGATGGGCATTTAGGTTGATTCCATGTCTTTGCTATTGTGAATAGTGCTGCAATGAATATAT

>84326_84326_7_SMURF1-TRIM4_SMURF1_chr7_98741349_ENST00000361125_TRIM4_chr7_99507283_ENST00000349062_length(amino acids)=330AA_BP=
MKKVMHLQDVEVKNATQWKDKIKSQRMRISTEFSKLHNFLVEEEDLFLQRLNKEEEETKKKLNENTLKLNQTIASLKKLILEVGEKSQAP
TLELLQNPKEVLTRSEIQDVNYSLEAVKVKTVCQIPLMKEMLKRFQVAVNLAEDTAHPKLVFSQEGRYVKNTASASSWPVFSSAWNYFAG
WRNPQKTAFVERFQHLPCVLGKNVFTSGKHYWEVESRDSLEVAVGVCREDVMGITDRSKMSPDVGIWAIYWSAAGYWPLIGFPGTPTQQE

--------------------------------------------------------------
>84326_84326_8_SMURF1-TRIM4_SMURF1_chr7_98741349_ENST00000361125_TRIM4_chr7_99507283_ENST00000354241_length(transcript)=1832nt_BP=375nt
GGCAGCGGCGGAAGCGGCGAGGGCGGCGGGCGTCCGGCTCTGAGGTGGTGGAGGCGGCGGAGGCGGCGGCGGAGGCGGCGGCGGCTCGGG
ACTGGGCTCGGCTGGAAGCAGCGAGGGTCAGAGCGCCGCAGCAAGCGCCGATCTCCCGGCTCGACCATCCGCCTGCCGCCCGGACGCCTG
GGCCGCGGAGTTTGTGTCCCGGCTCGGACCCCGGCGCCCAGCCCGGAGCCGTAACCTTGAGGCGGCGGCGGCGGGGCCGGGCCGGGCCGG
GCTGGGGGGCGGTGGCGCTGGATCCGCGGCTGCCCGATCGTTGGCGGGAGATGTCGAACCCCGGGACACGCAGGAACGGCTCCAGCATCA
AGATCCGTCTGACAGGAGAAACTTCTTAAGTCTCAGCGTAATCTCGTGGCCAAGATGAAGAAAGTCATGCATTTACAGGATGTAGAAGTG
AAGAACGCCACACAGTGGAAGGATAAGATAAAGAGTCAGCGAATGAGAATCAGCACGGAGTTTTCAAAGCTGCACAACTTCCTGGTTGAA
GAAGAGGACCTGTTTCTTCAGAGATTGAACAAAGAAGAAGAAGAGACGAAGAAGAAGCTGAATGAGAACACGTTAAAACTCAATCAAACT
ATCGCTTCATTGAAGAAGCTCATCTTAGAGGTGGGGGAGAAGAGCCAGGCTCCCACCCTGGAGCTGCTTCAGAATCCAAAAGAAGTGTTG
ACCAGGAGTGAGATCCAGGATGTGAACTATTCTCTTGAAGCTGTAAAGGTGAAGACAGTGTGCCAGATACCATTGATGAAGGAAATGCTA
AAGCGATTCCAAGCAACTAAAATAAAAACACAAAAACAAAACAGGCACAATATGTGAAACAACCGTTTTCAAAGCACCAGACGTCAGGCA
GTGAAGGACGGTGATTCCTGAGAAATGTGAAACAAATGAGGTCAGCCTATGATTGCCCTACCCTCTGCCTGAGGGAGTTTCCAGACCATG
TAAGGCTGAGGTAACTGAGGTAGAGCCAGGGAGACTTGCTGAGTTGAGGAATAGACCTGGGAGTTCACGGAGAACAAAGTAGTGAGAGTT
CGCAAAGTACTGGGCAGTATCCTGGAGCGGAGAGAGCCGGACACAGAGAGAACCCTCGCCATCTATGGAGGAGCTTCCTAGTTGTTTGGC
AGAGTTCTGATCAGCACATGCCTGTGAAAATCTACTCAAGGCTGGAGATAGAAGCTTCTAAAACGATTAGAGGGAACGGTTCCTGGTGCT
CACACAGGGCCAGGAACAGTGCCAGTTCCTATCAGCCACACCAGAAAACTCGTAGTTCACGGGCACTGAGTAGCGTACTCAGGAAAATCT
TGCCTCATTAGCAGAAAATATTTAGCCCTTGACTGGGTGCTGCTCCACACCCACCTTACAAATCATGAAAGCAAGACCCAAAGGGGTCAA
ACTCTTTCCAACTAACTTAACTGCATCCCAGGATAAAGCCCTAGAAAATTGGTAGAAATAAACAAAAAAAGAGCACCTAACAATATAAAT
TCACAATGTCTGGCATCCAGTCAAATATGCATGCAAAAAGATAGGAAAGCAGTGACCCATAATGGAGGAAAATAATCAACTGAAACTGAC
CTAGAATTGACACAGATGTTAGAATAAGCATGGAAGGACTTTAAAACATTTATTATGAGTGTATTCTGTAAAGAGGTACATAGAGACCAG
ATCAAAGTTTTAAAGATGAAAAATGTGATTAAGGCGAAGAATGCACTGGATGGGATTAATAGTTGATTAAATATTACAAAAGAAAAAATT

>84326_84326_8_SMURF1-TRIM4_SMURF1_chr7_98741349_ENST00000361125_TRIM4_chr7_99507283_ENST00000354241_length(amino acids)=150AA_BP=
MKKVMHLQDVEVKNATQWKDKIKSQRMRISTEFSKLHNFLVEEEDLFLQRLNKEEEETKKKLNENTLKLNQTIASLKKLILEVGEKSQAP

--------------------------------------------------------------
>84326_84326_9_SMURF1-TRIM4_SMURF1_chr7_98741349_ENST00000361125_TRIM4_chr7_99507283_ENST00000355947_length(transcript)=3157nt_BP=375nt
GGCAGCGGCGGAAGCGGCGAGGGCGGCGGGCGTCCGGCTCTGAGGTGGTGGAGGCGGCGGAGGCGGCGGCGGAGGCGGCGGCGGCTCGGG
ACTGGGCTCGGCTGGAAGCAGCGAGGGTCAGAGCGCCGCAGCAAGCGCCGATCTCCCGGCTCGACCATCCGCCTGCCGCCCGGACGCCTG
GGCCGCGGAGTTTGTGTCCCGGCTCGGACCCCGGCGCCCAGCCCGGAGCCGTAACCTTGAGGCGGCGGCGGCGGGGCCGGGCCGGGCCGG
GCTGGGGGGCGGTGGCGCTGGATCCGCGGCTGCCCGATCGTTGGCGGGAGATGTCGAACCCCGGGACACGCAGGAACGGCTCCAGCATCA
AGATCCGTCTGACAGGAGAAACTTCTTAAGTCTCAGCGTAATCTCGTGGCCAAGATGAAGAAAGTCATGCATTTACAGGATGTAGAAGTG
AAGAACGCCACACAGTGGAAGGATAAGATAAAGAGTCAGCGAATGAGAATCAGCACGGAGTTTTCAAAGCTGCACAACTTCCTGGTTGAA
GAAGAGGACCTGTTTCTTCAGAGATTGAACAAAGAAGAAGAAGAGACGAAGAAGAAGCTGAATGAGAACACGTTAAAACTCAATCAAACT
ATCGCTTCATTGAAGAAGCTCATCTTAGAGGTGGGGGAGAAGAGCCAGGCTCCCACCCTGGAGCTGCTTCAGAATCCAAAAGAAGTGTTG
ACCAGGAGTGAGATCCAGGATGTGAACTATTCTCTTGAAGCTGTAAAGGTGAAGACAGTGTGCCAGATACCATTGATGAAGGAAATGCTA
AAGCGATTCCAAGTGGCTGTAAACCTAGCTGAAGACACAGCTCATCCCAAACTCGTCTTCTCCCAGGAAGGGAGATACGTGAAAAATACA
GCATCAGCCAGTTCTTGGCCAGTGTTTTCTTCAGCATGGAACTACTTTGCTGGATGGAGGAATCCTCAGAAGACTGCTTTTGTAGAGAGA
TTTCAGCACTTACCCTGTGTTCTGGGAAAAAACGTTTTCACCTCAGGGAAACATTACTGGGAAGTTGAGAGTAGAGATAGTCTGGAGGTT
GCTGTTGGGGTGTGTCGGGAGGACGTCATGGGAATTACTGATCGTTCAAAAATGTCCCCAGATGTGGGCATCTGGGCGATTTATTGGAGT
GCTGCTGGCTATTGGCCCTTGATAGGCTTCCCTGGAACTCCCACCCAGCAAGAGCCAGCTCTCCACCGAGTGGGGGTTTACCTGGATCGT
GGGACTGGGAATGTCTCCTTCTACAGCGCTGTGGACGGAGTGCACCTGCACACCTTTTCTTGTTCTTCTGTCTCACGCCTCCGGCCATTT
TTTTGGTTGAGTCCATTAGCATCTTTAGTCATTCCACCAGTGACTGATAGGAAATGAGGCTTTTCTTCCCCTGACCAAAACTCCTTCCCT
GTAGTCCAGCTGAGGGACACACATCCCTGGGCCCTCTTCTGCCCTTCATGTCTCTATCCTGGATGGTCCATCTTCTGGGTCTCCCTAACG
GTACCGTTTGGTATCTGCCCTTTGTGTGCTTCACAAGAGGCAGTCCCATGGGAGGTGGGTCTGGCCAATGGAGATGGGACAGGAAATTTT
CCAAGACGCTTTTGGGAAATCTTTTTGTAGCTTTTAAAGAGATGTGCGGGGAAGACATATGGATGTTAGCAGCCATATTGGAACTGAGAA
CACAGGAATGGTGGAAAGGTAGAAGAAACAGAGTTTTTGTTGCCGTTGTGAAATTGTTGAAATTTCCTTCATGCCAAGCTTCTTGTTATA
TGAGATAATTACGCCCTTATTGTATAAGACAATTTTAGTTGTATTTGGTTACTTGCAGCCTGAAGTACCGTAACTGCACTAAAGGGACGT
AGTGTGAACATCCCGCAGTATAGGCTTAAGTCACTTTTGTGAAATTTGACAAAGGCATAGAATCTTTTTCTATCCAGTCAGGCATTGCCT
ATTCTTTCCAGTAACTACTGATTCCCCCACTTTTCTGTCTTAGAAAATTGTGGGAATCCCCCCTCACTCTGCCTATGTTGCACTCTCTCT
CTTCCCAACCATAACTCTGCCCTCAGCTATTAACTGTGCTGTGTATTTATCAAGTTGGTATGTTGTATGTACAGTGTTATTCATGTCATC
ATGAGAATGTTGAACGCTTGTTAAATATCTTTTGCTAGCCTCTTCATATGCTGTTGCATATGACTCTCATCACAACTCAGTGAGATGGAA
AGTCAAATCCTATTTGTACAAATGAGAAAACTGAACTCTTTAGAGTAACTAGCTCAGTATTGGCCAGCTGGTAAATGGCAGTGTTGGGAT
TAAAATCCAGTTCTTATCTACTCTCCCTTTATTCAGAAGCATTTATTGGATGTTGATCTTTGTTTCAGGTTTTGATTTTGTTACTTTTTT
ATACTGTGTATATTTTCCTCAGTCTACCCTTCTGCTCTAGATTGTCTGGACTCAGGAGATTGTGGCAGTTACTGGATAGTTATTTTTAAG
ATAATGATTGCTTTTCTCTGTTTATATAAGTCATGTGTACTTATTGTAGAAAGTTTGTAAGATGCAAAAAGTATAAAAATTAAAGTTATG
CACTACTAACATTTCAATATATTTTCTCCCAGATTTTCAGTAAAGACTTTCAGGCAGTGATTTAACGAGGATTTTATTTTAACTTATATT
TTAGTTTAAGGGGAACACGTGCAGGTTTGTTCTATAGATCAATTACATGTCACAGGGGTTTGGTGTACATATTATTTCATTACCCAGGTA
ATAAGCATAGTACCCAATAGATACTTTTTTGATACCCCACCCTCCTCCACCCTCTACCCTCAAGTAGTCCCTGGTGTCTGTTGTTCCCTT
TTTTGTGTCCATGGGTACTCAATGTTTAGCTCTCCCTTATACGTGAGAACATGTGATGTTTGGTTTTCTGTTCATGTGTTGGTTTGCTTA
GGGTAATGGCCTCCAGCTCCATCCATGTTGCTGCAAAGACATGATCTCATTCTTTTTTTATGGCTGCATAGTATTCCATGGTGTATATGT
ACTATGTTTTCTTTATCCAGTCTACTGTTGATGGGCATTTAGGTTGATTCCATGTCTTTGCTATTGTGAATAGTGCTGCAATGAATATAT

>84326_84326_9_SMURF1-TRIM4_SMURF1_chr7_98741349_ENST00000361125_TRIM4_chr7_99507283_ENST00000355947_length(amino acids)=330AA_BP=
MKKVMHLQDVEVKNATQWKDKIKSQRMRISTEFSKLHNFLVEEEDLFLQRLNKEEEETKKKLNENTLKLNQTIASLKKLILEVGEKSQAP
TLELLQNPKEVLTRSEIQDVNYSLEAVKVKTVCQIPLMKEMLKRFQVAVNLAEDTAHPKLVFSQEGRYVKNTASASSWPVFSSAWNYFAG
WRNPQKTAFVERFQHLPCVLGKNVFTSGKHYWEVESRDSLEVAVGVCREDVMGITDRSKMSPDVGIWAIYWSAAGYWPLIGFPGTPTQQE

--------------------------------------------------------------
>84326_84326_10_SMURF1-TRIM4_SMURF1_chr7_98741349_ENST00000361368_TRIM4_chr7_99507283_ENST00000349062_length(transcript)=3076nt_BP=294nt
CGGCTCGGGACTGGGCTCGGCTGGAAGCAGCGAGGGTCAGAGCGCCGCAGCAAGCGCCGATCTCCCGGCTCGACCATCCGCCTGCCGCCC
GGACGCCTGGGCCGCGGAGTTTGTGTCCCGGCTCGGACCCCGGCGCCCAGCCCGGAGCCGTAACCTTGAGGCGGCGGCGGCGGGGCCGGG
CCGGGCCGGGCTGGGGGGCGGTGGCGCTGGATCCGCGGCTGCCCGATCGTTGGCGGGAGATGTCGAACCCCGGGACACGCAGGAACGGCT
CCAGCATCAAGATCCGTCTGACAGGAGAAACTTCTTAAGTCTCAGCGTAATCTCGTGGCCAAGATGAAGAAAGTCATGCATTTACAGGAT
GTAGAAGTGAAGAACGCCACACAGTGGAAGGATAAGATAAAGAGTCAGCGAATGAGAATCAGCACGGAGTTTTCAAAGCTGCACAACTTC
CTGGTTGAAGAAGAGGACCTGTTTCTTCAGAGATTGAACAAAGAAGAAGAAGAGACGAAGAAGAAGCTGAATGAGAACACGTTAAAACTC
AATCAAACTATCGCTTCATTGAAGAAGCTCATCTTAGAGGTGGGGGAGAAGAGCCAGGCTCCCACCCTGGAGCTGCTTCAGAATCCAAAA
GAAGTGTTGACCAGGAGTGAGATCCAGGATGTGAACTATTCTCTTGAAGCTGTAAAGGTGAAGACAGTGTGCCAGATACCATTGATGAAG
GAAATGCTAAAGCGATTCCAAGTGGCTGTAAACCTAGCTGAAGACACAGCTCATCCCAAACTCGTCTTCTCCCAGGAAGGGAGATACGTG
AAAAATACAGCATCAGCCAGTTCTTGGCCAGTGTTTTCTTCAGCATGGAACTACTTTGCTGGATGGAGGAATCCTCAGAAGACTGCTTTT
GTAGAGAGATTTCAGCACTTACCCTGTGTTCTGGGAAAAAACGTTTTCACCTCAGGGAAACATTACTGGGAAGTTGAGAGTAGAGATAGT
CTGGAGGTTGCTGTTGGGGTGTGTCGGGAGGACGTCATGGGAATTACTGATCGTTCAAAAATGTCCCCAGATGTGGGCATCTGGGCGATT
TATTGGAGTGCTGCTGGCTATTGGCCCTTGATAGGCTTCCCTGGAACTCCCACCCAGCAAGAGCCAGCTCTCCACCGAGTGGGGGTTTAC
CTGGATCGTGGGACTGGGAATGTCTCCTTCTACAGCGCTGTGGACGGAGTGCACCTGCACACCTTTTCTTGTTCTTCTGTCTCACGCCTC
CGGCCATTTTTTTGGTTGAGTCCATTAGCATCTTTAGTCATTCCACCAGTGACTGATAGGAAATGAGGCTTTTCTTCCCCTGACCAAAAC
TCCTTCCCTGTAGTCCAGCTGAGGGACACACATCCCTGGGCCCTCTTCTGCCCTTCATGTCTCTATCCTGGATGGTCCATCTTCTGGGTC
TCCCTAACGGTACCGTTTGGTATCTGCCCTTTGTGTGCTTCACAAGAGGCAGTCCCATGGGAGGTGGGTCTGGCCAATGGAGATGGGACA
GGAAATTTTCCAAGACGCTTTTGGGAAATCTTTTTGTAGCTTTTAAAGAGATGTGCGGGGAAGACATATGGATGTTAGCAGCCATATTGG
AACTGAGAACACAGGAATGGTGGAAAGGTAGAAGAAACAGAGTTTTTGTTGCCGTTGTGAAATTGTTGAAATTTCCTTCATGCCAAGCTT
CTTGTTATATGAGATAATTACGCCCTTATTGTATAAGACAATTTTAGTTGTATTTGGTTACTTGCAGCCTGAAGTACCGTAACTGCACTA
AAGGGACGTAGTGTGAACATCCCGCAGTATAGGCTTAAGTCACTTTTGTGAAATTTGACAAAGGCATAGAATCTTTTTCTATCCAGTCAG
GCATTGCCTATTCTTTCCAGTAACTACTGATTCCCCCACTTTTCTGTCTTAGAAAATTGTGGGAATCCCCCCTCACTCTGCCTATGTTGC
ACTCTCTCTCTTCCCAACCATAACTCTGCCCTCAGCTATTAACTGTGCTGTGTATTTATCAAGTTGGTATGTTGTATGTACAGTGTTATT
CATGTCATCATGAGAATGTTGAACGCTTGTTAAATATCTTTTGCTAGCCTCTTCATATGCTGTTGCATATGACTCTCATCACAACTCAGT
GAGATGGAAAGTCAAATCCTATTTGTACAAATGAGAAAACTGAACTCTTTAGAGTAACTAGCTCAGTATTGGCCAGCTGGTAAATGGCAG
TGTTGGGATTAAAATCCAGTTCTTATCTACTCTCCCTTTATTCAGAAGCATTTATTGGATGTTGATCTTTGTTTCAGGTTTTGATTTTGT
TACTTTTTTATACTGTGTATATTTTCCTCAGTCTACCCTTCTGCTCTAGATTGTCTGGACTCAGGAGATTGTGGCAGTTACTGGATAGTT
ATTTTTAAGATAATGATTGCTTTTCTCTGTTTATATAAGTCATGTGTACTTATTGTAGAAAGTTTGTAAGATGCAAAAAGTATAAAAATT
AAAGTTATGCACTACTAACATTTCAATATATTTTCTCCCAGATTTTCAGTAAAGACTTTCAGGCAGTGATTTAACGAGGATTTTATTTTA
ACTTATATTTTAGTTTAAGGGGAACACGTGCAGGTTTGTTCTATAGATCAATTACATGTCACAGGGGTTTGGTGTACATATTATTTCATT
ACCCAGGTAATAAGCATAGTACCCAATAGATACTTTTTTGATACCCCACCCTCCTCCACCCTCTACCCTCAAGTAGTCCCTGGTGTCTGT
TGTTCCCTTTTTTGTGTCCATGGGTACTCAATGTTTAGCTCTCCCTTATACGTGAGAACATGTGATGTTTGGTTTTCTGTTCATGTGTTG
GTTTGCTTAGGGTAATGGCCTCCAGCTCCATCCATGTTGCTGCAAAGACATGATCTCATTCTTTTTTTATGGCTGCATAGTATTCCATGG
TGTATATGTACTATGTTTTCTTTATCCAGTCTACTGTTGATGGGCATTTAGGTTGATTCCATGTCTTTGCTATTGTGAATAGTGCTGCAA

>84326_84326_10_SMURF1-TRIM4_SMURF1_chr7_98741349_ENST00000361368_TRIM4_chr7_99507283_ENST00000349062_length(amino acids)=330AA_BP=
MKKVMHLQDVEVKNATQWKDKIKSQRMRISTEFSKLHNFLVEEEDLFLQRLNKEEEETKKKLNENTLKLNQTIASLKKLILEVGEKSQAP
TLELLQNPKEVLTRSEIQDVNYSLEAVKVKTVCQIPLMKEMLKRFQVAVNLAEDTAHPKLVFSQEGRYVKNTASASSWPVFSSAWNYFAG
WRNPQKTAFVERFQHLPCVLGKNVFTSGKHYWEVESRDSLEVAVGVCREDVMGITDRSKMSPDVGIWAIYWSAAGYWPLIGFPGTPTQQE

--------------------------------------------------------------
>84326_84326_11_SMURF1-TRIM4_SMURF1_chr7_98741349_ENST00000361368_TRIM4_chr7_99507283_ENST00000354241_length(transcript)=1751nt_BP=294nt
CGGCTCGGGACTGGGCTCGGCTGGAAGCAGCGAGGGTCAGAGCGCCGCAGCAAGCGCCGATCTCCCGGCTCGACCATCCGCCTGCCGCCC
GGACGCCTGGGCCGCGGAGTTTGTGTCCCGGCTCGGACCCCGGCGCCCAGCCCGGAGCCGTAACCTTGAGGCGGCGGCGGCGGGGCCGGG
CCGGGCCGGGCTGGGGGGCGGTGGCGCTGGATCCGCGGCTGCCCGATCGTTGGCGGGAGATGTCGAACCCCGGGACACGCAGGAACGGCT
CCAGCATCAAGATCCGTCTGACAGGAGAAACTTCTTAAGTCTCAGCGTAATCTCGTGGCCAAGATGAAGAAAGTCATGCATTTACAGGAT
GTAGAAGTGAAGAACGCCACACAGTGGAAGGATAAGATAAAGAGTCAGCGAATGAGAATCAGCACGGAGTTTTCAAAGCTGCACAACTTC
CTGGTTGAAGAAGAGGACCTGTTTCTTCAGAGATTGAACAAAGAAGAAGAAGAGACGAAGAAGAAGCTGAATGAGAACACGTTAAAACTC
AATCAAACTATCGCTTCATTGAAGAAGCTCATCTTAGAGGTGGGGGAGAAGAGCCAGGCTCCCACCCTGGAGCTGCTTCAGAATCCAAAA
GAAGTGTTGACCAGGAGTGAGATCCAGGATGTGAACTATTCTCTTGAAGCTGTAAAGGTGAAGACAGTGTGCCAGATACCATTGATGAAG
GAAATGCTAAAGCGATTCCAAGCAACTAAAATAAAAACACAAAAACAAAACAGGCACAATATGTGAAACAACCGTTTTCAAAGCACCAGA
CGTCAGGCAGTGAAGGACGGTGATTCCTGAGAAATGTGAAACAAATGAGGTCAGCCTATGATTGCCCTACCCTCTGCCTGAGGGAGTTTC
CAGACCATGTAAGGCTGAGGTAACTGAGGTAGAGCCAGGGAGACTTGCTGAGTTGAGGAATAGACCTGGGAGTTCACGGAGAACAAAGTA
GTGAGAGTTCGCAAAGTACTGGGCAGTATCCTGGAGCGGAGAGAGCCGGACACAGAGAGAACCCTCGCCATCTATGGAGGAGCTTCCTAG
TTGTTTGGCAGAGTTCTGATCAGCACATGCCTGTGAAAATCTACTCAAGGCTGGAGATAGAAGCTTCTAAAACGATTAGAGGGAACGGTT
CCTGGTGCTCACACAGGGCCAGGAACAGTGCCAGTTCCTATCAGCCACACCAGAAAACTCGTAGTTCACGGGCACTGAGTAGCGTACTCA
GGAAAATCTTGCCTCATTAGCAGAAAATATTTAGCCCTTGACTGGGTGCTGCTCCACACCCACCTTACAAATCATGAAAGCAAGACCCAA
AGGGGTCAAACTCTTTCCAACTAACTTAACTGCATCCCAGGATAAAGCCCTAGAAAATTGGTAGAAATAAACAAAAAAAGAGCACCTAAC
AATATAAATTCACAATGTCTGGCATCCAGTCAAATATGCATGCAAAAAGATAGGAAAGCAGTGACCCATAATGGAGGAAAATAATCAACT
GAAACTGACCTAGAATTGACACAGATGTTAGAATAAGCATGGAAGGACTTTAAAACATTTATTATGAGTGTATTCTGTAAAGAGGTACAT
AGAGACCAGATCAAAGTTTTAAAGATGAAAAATGTGATTAAGGCGAAGAATGCACTGGATGGGATTAATAGTTGATTAAATATTACAAAA

>84326_84326_11_SMURF1-TRIM4_SMURF1_chr7_98741349_ENST00000361368_TRIM4_chr7_99507283_ENST00000354241_length(amino acids)=150AA_BP=
MKKVMHLQDVEVKNATQWKDKIKSQRMRISTEFSKLHNFLVEEEDLFLQRLNKEEEETKKKLNENTLKLNQTIASLKKLILEVGEKSQAP

--------------------------------------------------------------
>84326_84326_12_SMURF1-TRIM4_SMURF1_chr7_98741349_ENST00000361368_TRIM4_chr7_99507283_ENST00000355947_length(transcript)=3076nt_BP=294nt
CGGCTCGGGACTGGGCTCGGCTGGAAGCAGCGAGGGTCAGAGCGCCGCAGCAAGCGCCGATCTCCCGGCTCGACCATCCGCCTGCCGCCC
GGACGCCTGGGCCGCGGAGTTTGTGTCCCGGCTCGGACCCCGGCGCCCAGCCCGGAGCCGTAACCTTGAGGCGGCGGCGGCGGGGCCGGG
CCGGGCCGGGCTGGGGGGCGGTGGCGCTGGATCCGCGGCTGCCCGATCGTTGGCGGGAGATGTCGAACCCCGGGACACGCAGGAACGGCT
CCAGCATCAAGATCCGTCTGACAGGAGAAACTTCTTAAGTCTCAGCGTAATCTCGTGGCCAAGATGAAGAAAGTCATGCATTTACAGGAT
GTAGAAGTGAAGAACGCCACACAGTGGAAGGATAAGATAAAGAGTCAGCGAATGAGAATCAGCACGGAGTTTTCAAAGCTGCACAACTTC
CTGGTTGAAGAAGAGGACCTGTTTCTTCAGAGATTGAACAAAGAAGAAGAAGAGACGAAGAAGAAGCTGAATGAGAACACGTTAAAACTC
AATCAAACTATCGCTTCATTGAAGAAGCTCATCTTAGAGGTGGGGGAGAAGAGCCAGGCTCCCACCCTGGAGCTGCTTCAGAATCCAAAA
GAAGTGTTGACCAGGAGTGAGATCCAGGATGTGAACTATTCTCTTGAAGCTGTAAAGGTGAAGACAGTGTGCCAGATACCATTGATGAAG
GAAATGCTAAAGCGATTCCAAGTGGCTGTAAACCTAGCTGAAGACACAGCTCATCCCAAACTCGTCTTCTCCCAGGAAGGGAGATACGTG
AAAAATACAGCATCAGCCAGTTCTTGGCCAGTGTTTTCTTCAGCATGGAACTACTTTGCTGGATGGAGGAATCCTCAGAAGACTGCTTTT
GTAGAGAGATTTCAGCACTTACCCTGTGTTCTGGGAAAAAACGTTTTCACCTCAGGGAAACATTACTGGGAAGTTGAGAGTAGAGATAGT
CTGGAGGTTGCTGTTGGGGTGTGTCGGGAGGACGTCATGGGAATTACTGATCGTTCAAAAATGTCCCCAGATGTGGGCATCTGGGCGATT
TATTGGAGTGCTGCTGGCTATTGGCCCTTGATAGGCTTCCCTGGAACTCCCACCCAGCAAGAGCCAGCTCTCCACCGAGTGGGGGTTTAC
CTGGATCGTGGGACTGGGAATGTCTCCTTCTACAGCGCTGTGGACGGAGTGCACCTGCACACCTTTTCTTGTTCTTCTGTCTCACGCCTC
CGGCCATTTTTTTGGTTGAGTCCATTAGCATCTTTAGTCATTCCACCAGTGACTGATAGGAAATGAGGCTTTTCTTCCCCTGACCAAAAC
TCCTTCCCTGTAGTCCAGCTGAGGGACACACATCCCTGGGCCCTCTTCTGCCCTTCATGTCTCTATCCTGGATGGTCCATCTTCTGGGTC
TCCCTAACGGTACCGTTTGGTATCTGCCCTTTGTGTGCTTCACAAGAGGCAGTCCCATGGGAGGTGGGTCTGGCCAATGGAGATGGGACA
GGAAATTTTCCAAGACGCTTTTGGGAAATCTTTTTGTAGCTTTTAAAGAGATGTGCGGGGAAGACATATGGATGTTAGCAGCCATATTGG
AACTGAGAACACAGGAATGGTGGAAAGGTAGAAGAAACAGAGTTTTTGTTGCCGTTGTGAAATTGTTGAAATTTCCTTCATGCCAAGCTT
CTTGTTATATGAGATAATTACGCCCTTATTGTATAAGACAATTTTAGTTGTATTTGGTTACTTGCAGCCTGAAGTACCGTAACTGCACTA
AAGGGACGTAGTGTGAACATCCCGCAGTATAGGCTTAAGTCACTTTTGTGAAATTTGACAAAGGCATAGAATCTTTTTCTATCCAGTCAG
GCATTGCCTATTCTTTCCAGTAACTACTGATTCCCCCACTTTTCTGTCTTAGAAAATTGTGGGAATCCCCCCTCACTCTGCCTATGTTGC
ACTCTCTCTCTTCCCAACCATAACTCTGCCCTCAGCTATTAACTGTGCTGTGTATTTATCAAGTTGGTATGTTGTATGTACAGTGTTATT
CATGTCATCATGAGAATGTTGAACGCTTGTTAAATATCTTTTGCTAGCCTCTTCATATGCTGTTGCATATGACTCTCATCACAACTCAGT
GAGATGGAAAGTCAAATCCTATTTGTACAAATGAGAAAACTGAACTCTTTAGAGTAACTAGCTCAGTATTGGCCAGCTGGTAAATGGCAG
TGTTGGGATTAAAATCCAGTTCTTATCTACTCTCCCTTTATTCAGAAGCATTTATTGGATGTTGATCTTTGTTTCAGGTTTTGATTTTGT
TACTTTTTTATACTGTGTATATTTTCCTCAGTCTACCCTTCTGCTCTAGATTGTCTGGACTCAGGAGATTGTGGCAGTTACTGGATAGTT
ATTTTTAAGATAATGATTGCTTTTCTCTGTTTATATAAGTCATGTGTACTTATTGTAGAAAGTTTGTAAGATGCAAAAAGTATAAAAATT
AAAGTTATGCACTACTAACATTTCAATATATTTTCTCCCAGATTTTCAGTAAAGACTTTCAGGCAGTGATTTAACGAGGATTTTATTTTA
ACTTATATTTTAGTTTAAGGGGAACACGTGCAGGTTTGTTCTATAGATCAATTACATGTCACAGGGGTTTGGTGTACATATTATTTCATT
ACCCAGGTAATAAGCATAGTACCCAATAGATACTTTTTTGATACCCCACCCTCCTCCACCCTCTACCCTCAAGTAGTCCCTGGTGTCTGT
TGTTCCCTTTTTTGTGTCCATGGGTACTCAATGTTTAGCTCTCCCTTATACGTGAGAACATGTGATGTTTGGTTTTCTGTTCATGTGTTG
GTTTGCTTAGGGTAATGGCCTCCAGCTCCATCCATGTTGCTGCAAAGACATGATCTCATTCTTTTTTTATGGCTGCATAGTATTCCATGG
TGTATATGTACTATGTTTTCTTTATCCAGTCTACTGTTGATGGGCATTTAGGTTGATTCCATGTCTTTGCTATTGTGAATAGTGCTGCAA

>84326_84326_12_SMURF1-TRIM4_SMURF1_chr7_98741349_ENST00000361368_TRIM4_chr7_99507283_ENST00000355947_length(amino acids)=330AA_BP=
MKKVMHLQDVEVKNATQWKDKIKSQRMRISTEFSKLHNFLVEEEDLFLQRLNKEEEETKKKLNENTLKLNQTIASLKKLILEVGEKSQAP
TLELLQNPKEVLTRSEIQDVNYSLEAVKVKTVCQIPLMKEMLKRFQVAVNLAEDTAHPKLVFSQEGRYVKNTASASSWPVFSSAWNYFAG
WRNPQKTAFVERFQHLPCVLGKNVFTSGKHYWEVESRDSLEVAVGVCREDVMGITDRSKMSPDVGIWAIYWSAAGYWPLIGFPGTPTQQE

--------------------------------------------------------------

Top

Fusion Gene PPI Analysis for SMURF1-TRIM4


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


Top

Related Drugs for SMURF1-TRIM4


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

Top

Related Diseases for SMURF1-TRIM4


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource