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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:SNAP23-EIF2B5 (FusionGDB2 ID:84404)

Fusion Gene Summary for SNAP23-EIF2B5

check button Fusion gene summary
Fusion gene informationFusion gene name: SNAP23-EIF2B5
Fusion gene ID: 84404
HgeneTgene
Gene symbol

SNAP23

EIF2B5

Gene ID

8773

8893

Gene namesynaptosome associated protein 23eukaryotic translation initiation factor 2B subunit epsilon
SynonymsHsT17016|SNAP-23|SNAP23A|SNAP23BCACH|CLE|EIF-2B|EIF2Bepsilon|LVWM
Cytomap

15q15.1-q15.2

3q27.1

Type of geneprotein-codingprotein-coding
Descriptionsynaptosomal-associated protein 23synaptosomal-associated protein, 23kDsynaptosomal-associated protein, 23kDasynaptosome associated protein 23kDavesicle-membrane fusion protein SNAP-23translation initiation factor eIF-2B subunit epsiloneIF-2B GDP-GTP exchange factor subunit epsiloneukaryotic translation initiation factor 2B, subunit 5 epsilon, 82kDa
Modification date2020031320200320
UniProtAcc.

Q13144

Ensembl transtripts involved in fusion geneENST00000249647, ENST00000349777, 
ENST00000397138, ENST00000564153, 
ENST00000567094, ENST00000566141, 
ENST00000432569, ENST00000498831, 
ENST00000273783, ENST00000444495, 
Fusion gene scores* DoF score4 X 3 X 4=484 X 4 X 3=48
# samples 45
** MAII scorelog2(4/48*10)=-0.263034405833794
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(5/48*10)=0.0588936890535686
effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs).
DoF>8 and MAII>0
Context

PubMed: SNAP23 [Title/Abstract] AND EIF2B5 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointSNAP23(42805645)-EIF2B5(183859713), # samples:1
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
TgeneEIF2B5

GO:0006413

translational initiation

16289705

TgeneEIF2B5

GO:0050852

T cell receptor signaling pathway

8626696


check buttonFusion gene breakpoints across SNAP23 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across EIF2B5 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4GBMTCGA-14-1402-02ASNAP23chr15

42805645

+EIF2B5chr3

183859713

+


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Fusion Gene ORF analysis for SNAP23-EIF2B5

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000249647ENST00000432569SNAP23chr15

42805645

+EIF2B5chr3

183859713

+
5CDS-intronENST00000249647ENST00000498831SNAP23chr15

42805645

+EIF2B5chr3

183859713

+
5CDS-intronENST00000349777ENST00000432569SNAP23chr15

42805645

+EIF2B5chr3

183859713

+
5CDS-intronENST00000349777ENST00000498831SNAP23chr15

42805645

+EIF2B5chr3

183859713

+
5CDS-intronENST00000397138ENST00000432569SNAP23chr15

42805645

+EIF2B5chr3

183859713

+
5CDS-intronENST00000397138ENST00000498831SNAP23chr15

42805645

+EIF2B5chr3

183859713

+
5CDS-intronENST00000564153ENST00000432569SNAP23chr15

42805645

+EIF2B5chr3

183859713

+
5CDS-intronENST00000564153ENST00000498831SNAP23chr15

42805645

+EIF2B5chr3

183859713

+
5CDS-intronENST00000567094ENST00000432569SNAP23chr15

42805645

+EIF2B5chr3

183859713

+
5CDS-intronENST00000567094ENST00000498831SNAP23chr15

42805645

+EIF2B5chr3

183859713

+
In-frameENST00000249647ENST00000273783SNAP23chr15

42805645

+EIF2B5chr3

183859713

+
In-frameENST00000249647ENST00000444495SNAP23chr15

42805645

+EIF2B5chr3

183859713

+
In-frameENST00000349777ENST00000273783SNAP23chr15

42805645

+EIF2B5chr3

183859713

+
In-frameENST00000349777ENST00000444495SNAP23chr15

42805645

+EIF2B5chr3

183859713

+
In-frameENST00000397138ENST00000273783SNAP23chr15

42805645

+EIF2B5chr3

183859713

+
In-frameENST00000397138ENST00000444495SNAP23chr15

42805645

+EIF2B5chr3

183859713

+
In-frameENST00000564153ENST00000273783SNAP23chr15

42805645

+EIF2B5chr3

183859713

+
In-frameENST00000564153ENST00000444495SNAP23chr15

42805645

+EIF2B5chr3

183859713

+
In-frameENST00000567094ENST00000273783SNAP23chr15

42805645

+EIF2B5chr3

183859713

+
In-frameENST00000567094ENST00000444495SNAP23chr15

42805645

+EIF2B5chr3

183859713

+
intron-3CDSENST00000566141ENST00000273783SNAP23chr15

42805645

+EIF2B5chr3

183859713

+
intron-3CDSENST00000566141ENST00000444495SNAP23chr15

42805645

+EIF2B5chr3

183859713

+
intron-intronENST00000566141ENST00000432569SNAP23chr15

42805645

+EIF2B5chr3

183859713

+
intron-intronENST00000566141ENST00000498831SNAP23chr15

42805645

+EIF2B5chr3

183859713

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000249647SNAP23chr1542805645+ENST00000444495EIF2B5chr3183859713+18396164681577369
ENST00000249647SNAP23chr1542805645+ENST00000273783EIF2B5chr3183859713+19936164681625385
ENST00000564153SNAP23chr1542805645+ENST00000444495EIF2B5chr3183859713+1465242941203369
ENST00000564153SNAP23chr1542805645+ENST00000273783EIF2B5chr3183859713+1619242941251385
ENST00000349777SNAP23chr1542805645+ENST00000444495EIF2B5chr3183859713+1462239911200369
ENST00000349777SNAP23chr1542805645+ENST00000273783EIF2B5chr3183859713+1616239911248385
ENST00000567094SNAP23chr1542805645+ENST00000444495EIF2B5chr3183859713+1457234861195369
ENST00000567094SNAP23chr1542805645+ENST00000273783EIF2B5chr3183859713+1611234861243385
ENST00000397138SNAP23chr1542805645+ENST00000444495EIF2B5chr3183859713+137114801109369
ENST00000397138SNAP23chr1542805645+ENST00000273783EIF2B5chr3183859713+152514801157385

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000249647ENST00000444495SNAP23chr1542805645+EIF2B5chr3183859713+0.002436990.997563
ENST00000249647ENST00000273783SNAP23chr1542805645+EIF2B5chr3183859713+0.0033653710.99663466
ENST00000564153ENST00000444495SNAP23chr1542805645+EIF2B5chr3183859713+0.0026898730.99731016
ENST00000564153ENST00000273783SNAP23chr1542805645+EIF2B5chr3183859713+0.0037956370.99620444
ENST00000349777ENST00000444495SNAP23chr1542805645+EIF2B5chr3183859713+0.0026094560.99739057
ENST00000349777ENST00000273783SNAP23chr1542805645+EIF2B5chr3183859713+0.0037664460.9962335
ENST00000567094ENST00000444495SNAP23chr1542805645+EIF2B5chr3183859713+0.0026227140.9973773
ENST00000567094ENST00000273783SNAP23chr1542805645+EIF2B5chr3183859713+0.0038751340.9961249
ENST00000397138ENST00000444495SNAP23chr1542805645+EIF2B5chr3183859713+0.0027862520.9972138
ENST00000397138ENST00000273783SNAP23chr1542805645+EIF2B5chr3183859713+0.0041615540.9958384

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Fusion Genomic Features for SNAP23-EIF2B5


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
SNAP23chr1542805645+EIF2B5chr3183859712+4.77E-070.9999995
SNAP23chr1542805645+EIF2B5chr3183859712+4.77E-070.9999995

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for SNAP23-EIF2B5


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr15:42805645/chr3:183859713)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
.EIF2B5

Q13144

FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Catalyzes the exchange of eukaryotic initiation factor 2-bound GDP for GTP.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneEIF2B5chr15:42805645chr3:183859713ENST00000273783616505_509385722.0Compositional biasNote=Poly-Glu
TgeneEIF2B5chr15:42805645chr3:183859713ENST00000273783616543_720385722.0DomainW2

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneSNAP23chr15:42805645chr3:183859713ENST00000249647+4823_7649212.0Coiled coilOntology_term=ECO:0000269
HgeneSNAP23chr15:42805645chr3:183859713ENST00000349777+4723_7649159.0Coiled coilOntology_term=ECO:0000269
HgeneSNAP23chr15:42805645chr3:183859713ENST00000397138+3623_7649159.0Coiled coilOntology_term=ECO:0000269
HgeneSNAP23chr15:42805645chr3:183859713ENST00000249647+48146_20849212.0Domaint-SNARE coiled-coil homology 2
HgeneSNAP23chr15:42805645chr3:183859713ENST00000249647+4814_7649212.0Domaint-SNARE coiled-coil homology 1
HgeneSNAP23chr15:42805645chr3:183859713ENST00000349777+47146_20849159.0Domaint-SNARE coiled-coil homology 2
HgeneSNAP23chr15:42805645chr3:183859713ENST00000349777+4714_7649159.0Domaint-SNARE coiled-coil homology 1
HgeneSNAP23chr15:42805645chr3:183859713ENST00000397138+36146_20849159.0Domaint-SNARE coiled-coil homology 2
HgeneSNAP23chr15:42805645chr3:183859713ENST00000397138+3614_7649159.0Domaint-SNARE coiled-coil homology 1


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Fusion Gene Sequence for SNAP23-EIF2B5


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>84404_84404_1_SNAP23-EIF2B5_SNAP23_chr15_42805645_ENST00000249647_EIF2B5_chr3_183859713_ENST00000273783_length(transcript)=1993nt_BP=616nt
AGGCGCCTCAAATTTTCTATGTGCTATGCACTGTATTCTATCCACTATAATTTGTTTACATATCTATATCTTAGTCTAGACATATTGAAA
GGCGATGAAGAGCAGGGAAAGCACTGTATTCGCTTTCTTTTCTTCAGCGTTCATCCAGCACAGTGCCTGGCATACGGTTTGCCCTCAGTA
AATGTTTATTGCATGAACACCTCCCAGCTTCGGGCAGGACTGAAATCTATCCGGTTAACTAGTGAATTCCCAGACTCTCCGTCTGCGTGG
CAGGGACATTTAAACCCCCAGCACCGTGATTGGCTCCAGCTGCAGGGGTGTGTCTGTGTCCGCGGCGAACGGGAAGTGAGCAGGCGCGCG
GGCTCGGCGCGCGCAGGCGCGACTAGGGTGCAGCGCCAGGTCCGGTGTTGGGGTGTCCGAGTTGCCGCCGGAGAGGAGTGGCCTCGCCCG
CTTGAGTTTTGATTCATCATGGATAATCTGTCATCAGAAGAAATTCAACAGAGAGCTCACCAGATTACTGATGAGTCTCTGGAAAGTACG
AGGAGAATCCTGGGTTTAGCCATTGAGTCTCAGGATGCAGGAATCAAGACCATCACTATGCTGGATGAACAAAAGGGTGATAACGTGGTG
CTGGACCAGACCTACCTGTGGCAGGGTGTTCGAGTGGCGGCTGGAGCACAGATCCATCAGTCTCTGCTTTGTGACAATGCTGAGGTCAAG
GAACGAGTGACACTGAAACCACGCTCTGTCCTCACTTCCCAGGTGGTCGTGGGCCCAAATATCACGCTGCCTGAGGGCTCGGTGATCTCT
TTGCACCCTCCAGATGCAGAGGAAGATGAAGATGATGGCGAGTTCAGTGATGATTCTGGGGCTGACCAAGAAAAGGACAAAGTGAAGATG
AAAGGTTACAATCCAGCAGAAGTAGGAGCTGCTGGCAAGGGCTACCTCTGGAAAGCTGCAGGCATGAACATGGAGGAAGAGGAGGAACTG
CAGCAGAATCTGTGGGGACTCAAGATCAACATGGAAGAAGAGAGTGAAAGTGAAAGTGAGCAAAGTATGGATTCTGAGGAGCCGGACAGC
CGGGGAGGCTCCCCTCAGATGGATGACATCAAAGTGTTCCAGAATGAAGTTTTAGGAACACTACAGCGGGGCAAAGAGGAGAACATTTCT
TGTGACAATCTCGTCCTGGAAATCAACTCTCTCAAGTATGCCTATAACATAAGTCTAAAGGAGGTGATGCAGGTACTGAGCCACGTGGTC
CTGGAGTTCCCCCTGCAACAGATGGATTCCCCGCTTGACTCAAGCCGCTACTGTGCCCTGCTGCTTCCTCTGCTAAAGGCCTGGAGCCCT
GTTTTTAGGAACTACATAAAGCGCGCAGCCGACCATTTGGAAGCGTTAGCAGCCATTGAGGACTTCTTCCTAGAGCATGAAGCTCTTGGT
ATTTCCATGGCCAAGGTACTGATGGCTTTCTACCAGCTGGAGATCCTGGCTGAGGAAACAATTCTGAGCTGGTTCAGCCAAAGAGATACA
ACTGACAAGGGCCAGCAGTTGCGCAAGAATCAACAGCTGCAGAGGTTCATCCAGTGGCTAAAAGAGGCAGAAGAGGAGTCATCTGAAGAT
GACTGAAGTCACACTGCCTGCTCCTTTGGGTGTGATTGAGTGCCCTCCTGGCTCCTGGGCTGGGACAAGTGAGGAACTAGCTGCAGAGGG
ATGAGTGACCACCATCCAGGCTGAGACTGAAAGGAGCAGAGGCTGGAACTACAGTATTCTTTCCCCTGCTAGCAACCATGTGCCTCCCAT
CCTGACTGTGGAGTTGGGATGTGGAAGTGGGGCTGGAACAAAGCTTCTGCCTAGGGAGGAGCTAAGCAGGCCCGGCAGTTGGAGGAAGGC
CAGAGGAACAGCTTTGTGCTCCGGCTTTCCCTCAGGGAACAGCAGAGAGCAGTTGGCTCTTTCTGCTGCTTGTATATGTTAATATTAAAA

>84404_84404_1_SNAP23-EIF2B5_SNAP23_chr15_42805645_ENST00000249647_EIF2B5_chr3_183859713_ENST00000273783_length(amino acids)=385AA_BP=49
MDNLSSEEIQQRAHQITDESLESTRRILGLAIESQDAGIKTITMLDEQKGDNVVLDQTYLWQGVRVAAGAQIHQSLLCDNAEVKERVTLK
PRSVLTSQVVVGPNITLPEGSVISLHPPDAEEDEDDGEFSDDSGADQEKDKVKMKGYNPAEVGAAGKGYLWKAAGMNMEEEEELQQNLWG
LKINMEEESESESEQSMDSEEPDSRGGSPQMDDIKVFQNEVLGTLQRGKEENISCDNLVLEINSLKYAYNISLKEVMQVLSHVVLEFPLQ
QMDSPLDSSRYCALLLPLLKAWSPVFRNYIKRAADHLEALAAIEDFFLEHEALGISMAKVLMAFYQLEILAEETILSWFSQRDTTDKGQQ

--------------------------------------------------------------
>84404_84404_2_SNAP23-EIF2B5_SNAP23_chr15_42805645_ENST00000249647_EIF2B5_chr3_183859713_ENST00000444495_length(transcript)=1839nt_BP=616nt
AGGCGCCTCAAATTTTCTATGTGCTATGCACTGTATTCTATCCACTATAATTTGTTTACATATCTATATCTTAGTCTAGACATATTGAAA
GGCGATGAAGAGCAGGGAAAGCACTGTATTCGCTTTCTTTTCTTCAGCGTTCATCCAGCACAGTGCCTGGCATACGGTTTGCCCTCAGTA
AATGTTTATTGCATGAACACCTCCCAGCTTCGGGCAGGACTGAAATCTATCCGGTTAACTAGTGAATTCCCAGACTCTCCGTCTGCGTGG
CAGGGACATTTAAACCCCCAGCACCGTGATTGGCTCCAGCTGCAGGGGTGTGTCTGTGTCCGCGGCGAACGGGAAGTGAGCAGGCGCGCG
GGCTCGGCGCGCGCAGGCGCGACTAGGGTGCAGCGCCAGGTCCGGTGTTGGGGTGTCCGAGTTGCCGCCGGAGAGGAGTGGCCTCGCCCG
CTTGAGTTTTGATTCATCATGGATAATCTGTCATCAGAAGAAATTCAACAGAGAGCTCACCAGATTACTGATGAGTCTCTGGAAAGTACG
AGGAGAATCCTGGGTTTAGCCATTGAGTCTCAGGATGCAGGAATCAAGACCATCACTATGCTGGATGAACAAAAGGGTGATAACGTGGTG
CTGGACCAGACCTACCTGTGGCAGGGTGTTCGAGTGGCGGCTGGAGCACAGATCCATCAGTCTCTGCTTTGTGACAATGCTGAGGTCAAG
GAACGAGTGACACTGAAACCACGCTCTGTCCTCACTTCCCAGGTGGTCGTGGGCCCAAATATCACGCTGCCTGAGGGCTCGGTGATCTCT
TTGCACCCTCCAGATGCAGAGGAAGATGAAGATGATGGCGAGTTCAGTGATGATTCTGGGGCTGACCAAGAAAAGGACAAAGTGAAGATG
AAAGGTTACAATCCAGCAGAAGTAGGAGCTGCTGGCAAGGGCTACCTCTGGAAAGCTGCAGGCATGAACATGGAGGAAGAGGAGGAACTG
CAGCAGAATCTGTGGGGACTCAAGATCAACATGGAAGAAGAGAGTGAAAGTGAAAGTGAGCAAAGTATGGATTCTGAGGAGCCGGACAGC
CGGGGAGGCTCCCCTCAGATGGATGACATCAAAGTGTTCCAGAATGAAGTTTTAGGAACACTACAGCGGGGCAAAGAGGAGAACATTTCT
TGTGACAATCTCGTCCTGGAAATCAACTCTCTCAAGTATGCCTATAACATAAGTCTAAAGGAGGTGATGCAGGTACTGAGCCACGTGGTC
CTGGAGTTCCCCCTGCAACAGATGGATTCCCCGCTTGACTCAAGCCGCTACTGTGCCCTGCTGCTTCCTCTGCTAAAGGCCTGGAGCCCT
GTTTTTAGGAACTACATAAAGCGCGCAGCCGACCATTTGGAAGCGTTAGCAGCCATTGAGGACTTCTTCCTAGAGCATGAAGCTCTTGGT
ATTTCCATGGCCAAGGTACTGATGGCTTTCTACCAGCTGGAGATCCTGGCTGAGGAAACAATTCTGAGCTGGTTCAGCCAAAGAGATACA
ACTGACAAGGGCCAGCAGTTGCGCAAGAATCAACAGGTGGTGTGTTAAAGGCTTGACTAAACGGGATTCAGTTTTTCTACTTTTGTAAGA
CTTCAAATACAAATGTTCTTAAGTCAGAGGTGCCTCCACCCACATGATGGACTCACCTGCAGCCATTCAGAAGGAGGACGGGCAAACCGC
ACAGTGGCACGGAAAGACAAGGATGATGGCCGCGAAGTGGGGGCAGCATCCGATCCACATTCTAAAAGTAGCATAATCACCATTACTAAA

>84404_84404_2_SNAP23-EIF2B5_SNAP23_chr15_42805645_ENST00000249647_EIF2B5_chr3_183859713_ENST00000444495_length(amino acids)=369AA_BP=49
MDNLSSEEIQQRAHQITDESLESTRRILGLAIESQDAGIKTITMLDEQKGDNVVLDQTYLWQGVRVAAGAQIHQSLLCDNAEVKERVTLK
PRSVLTSQVVVGPNITLPEGSVISLHPPDAEEDEDDGEFSDDSGADQEKDKVKMKGYNPAEVGAAGKGYLWKAAGMNMEEEEELQQNLWG
LKINMEEESESESEQSMDSEEPDSRGGSPQMDDIKVFQNEVLGTLQRGKEENISCDNLVLEINSLKYAYNISLKEVMQVLSHVVLEFPLQ
QMDSPLDSSRYCALLLPLLKAWSPVFRNYIKRAADHLEALAAIEDFFLEHEALGISMAKVLMAFYQLEILAEETILSWFSQRDTTDKGQQ

--------------------------------------------------------------
>84404_84404_3_SNAP23-EIF2B5_SNAP23_chr15_42805645_ENST00000349777_EIF2B5_chr3_183859713_ENST00000273783_length(transcript)=1616nt_BP=239nt
CGCGACTAGGGTGCAGCGCCAGGTCCGGTGTTGGGGTGTCCGAGTTGCCGCCGGAGAGGAGTGGCCTCGCCCGCTTGAGTTTTGATTCAT
CATGGATAATCTGTCATCAGAAGAAATTCAACAGAGAGCTCACCAGATTACTGATGAGTCTCTGGAAAGTACGAGGAGAATCCTGGGTTT
AGCCATTGAGTCTCAGGATGCAGGAATCAAGACCATCACTATGCTGGATGAACAAAAGGGTGATAACGTGGTGCTGGACCAGACCTACCT
GTGGCAGGGTGTTCGAGTGGCGGCTGGAGCACAGATCCATCAGTCTCTGCTTTGTGACAATGCTGAGGTCAAGGAACGAGTGACACTGAA
ACCACGCTCTGTCCTCACTTCCCAGGTGGTCGTGGGCCCAAATATCACGCTGCCTGAGGGCTCGGTGATCTCTTTGCACCCTCCAGATGC
AGAGGAAGATGAAGATGATGGCGAGTTCAGTGATGATTCTGGGGCTGACCAAGAAAAGGACAAAGTGAAGATGAAAGGTTACAATCCAGC
AGAAGTAGGAGCTGCTGGCAAGGGCTACCTCTGGAAAGCTGCAGGCATGAACATGGAGGAAGAGGAGGAACTGCAGCAGAATCTGTGGGG
ACTCAAGATCAACATGGAAGAAGAGAGTGAAAGTGAAAGTGAGCAAAGTATGGATTCTGAGGAGCCGGACAGCCGGGGAGGCTCCCCTCA
GATGGATGACATCAAAGTGTTCCAGAATGAAGTTTTAGGAACACTACAGCGGGGCAAAGAGGAGAACATTTCTTGTGACAATCTCGTCCT
GGAAATCAACTCTCTCAAGTATGCCTATAACATAAGTCTAAAGGAGGTGATGCAGGTACTGAGCCACGTGGTCCTGGAGTTCCCCCTGCA
ACAGATGGATTCCCCGCTTGACTCAAGCCGCTACTGTGCCCTGCTGCTTCCTCTGCTAAAGGCCTGGAGCCCTGTTTTTAGGAACTACAT
AAAGCGCGCAGCCGACCATTTGGAAGCGTTAGCAGCCATTGAGGACTTCTTCCTAGAGCATGAAGCTCTTGGTATTTCCATGGCCAAGGT
ACTGATGGCTTTCTACCAGCTGGAGATCCTGGCTGAGGAAACAATTCTGAGCTGGTTCAGCCAAAGAGATACAACTGACAAGGGCCAGCA
GTTGCGCAAGAATCAACAGCTGCAGAGGTTCATCCAGTGGCTAAAAGAGGCAGAAGAGGAGTCATCTGAAGATGACTGAAGTCACACTGC
CTGCTCCTTTGGGTGTGATTGAGTGCCCTCCTGGCTCCTGGGCTGGGACAAGTGAGGAACTAGCTGCAGAGGGATGAGTGACCACCATCC
AGGCTGAGACTGAAAGGAGCAGAGGCTGGAACTACAGTATTCTTTCCCCTGCTAGCAACCATGTGCCTCCCATCCTGACTGTGGAGTTGG
GATGTGGAAGTGGGGCTGGAACAAAGCTTCTGCCTAGGGAGGAGCTAAGCAGGCCCGGCAGTTGGAGGAAGGCCAGAGGAACAGCTTTGT

>84404_84404_3_SNAP23-EIF2B5_SNAP23_chr15_42805645_ENST00000349777_EIF2B5_chr3_183859713_ENST00000273783_length(amino acids)=385AA_BP=49
MDNLSSEEIQQRAHQITDESLESTRRILGLAIESQDAGIKTITMLDEQKGDNVVLDQTYLWQGVRVAAGAQIHQSLLCDNAEVKERVTLK
PRSVLTSQVVVGPNITLPEGSVISLHPPDAEEDEDDGEFSDDSGADQEKDKVKMKGYNPAEVGAAGKGYLWKAAGMNMEEEEELQQNLWG
LKINMEEESESESEQSMDSEEPDSRGGSPQMDDIKVFQNEVLGTLQRGKEENISCDNLVLEINSLKYAYNISLKEVMQVLSHVVLEFPLQ
QMDSPLDSSRYCALLLPLLKAWSPVFRNYIKRAADHLEALAAIEDFFLEHEALGISMAKVLMAFYQLEILAEETILSWFSQRDTTDKGQQ

--------------------------------------------------------------
>84404_84404_4_SNAP23-EIF2B5_SNAP23_chr15_42805645_ENST00000349777_EIF2B5_chr3_183859713_ENST00000444495_length(transcript)=1462nt_BP=239nt
CGCGACTAGGGTGCAGCGCCAGGTCCGGTGTTGGGGTGTCCGAGTTGCCGCCGGAGAGGAGTGGCCTCGCCCGCTTGAGTTTTGATTCAT
CATGGATAATCTGTCATCAGAAGAAATTCAACAGAGAGCTCACCAGATTACTGATGAGTCTCTGGAAAGTACGAGGAGAATCCTGGGTTT
AGCCATTGAGTCTCAGGATGCAGGAATCAAGACCATCACTATGCTGGATGAACAAAAGGGTGATAACGTGGTGCTGGACCAGACCTACCT
GTGGCAGGGTGTTCGAGTGGCGGCTGGAGCACAGATCCATCAGTCTCTGCTTTGTGACAATGCTGAGGTCAAGGAACGAGTGACACTGAA
ACCACGCTCTGTCCTCACTTCCCAGGTGGTCGTGGGCCCAAATATCACGCTGCCTGAGGGCTCGGTGATCTCTTTGCACCCTCCAGATGC
AGAGGAAGATGAAGATGATGGCGAGTTCAGTGATGATTCTGGGGCTGACCAAGAAAAGGACAAAGTGAAGATGAAAGGTTACAATCCAGC
AGAAGTAGGAGCTGCTGGCAAGGGCTACCTCTGGAAAGCTGCAGGCATGAACATGGAGGAAGAGGAGGAACTGCAGCAGAATCTGTGGGG
ACTCAAGATCAACATGGAAGAAGAGAGTGAAAGTGAAAGTGAGCAAAGTATGGATTCTGAGGAGCCGGACAGCCGGGGAGGCTCCCCTCA
GATGGATGACATCAAAGTGTTCCAGAATGAAGTTTTAGGAACACTACAGCGGGGCAAAGAGGAGAACATTTCTTGTGACAATCTCGTCCT
GGAAATCAACTCTCTCAAGTATGCCTATAACATAAGTCTAAAGGAGGTGATGCAGGTACTGAGCCACGTGGTCCTGGAGTTCCCCCTGCA
ACAGATGGATTCCCCGCTTGACTCAAGCCGCTACTGTGCCCTGCTGCTTCCTCTGCTAAAGGCCTGGAGCCCTGTTTTTAGGAACTACAT
AAAGCGCGCAGCCGACCATTTGGAAGCGTTAGCAGCCATTGAGGACTTCTTCCTAGAGCATGAAGCTCTTGGTATTTCCATGGCCAAGGT
ACTGATGGCTTTCTACCAGCTGGAGATCCTGGCTGAGGAAACAATTCTGAGCTGGTTCAGCCAAAGAGATACAACTGACAAGGGCCAGCA
GTTGCGCAAGAATCAACAGGTGGTGTGTTAAAGGCTTGACTAAACGGGATTCAGTTTTTCTACTTTTGTAAGACTTCAAATACAAATGTT
CTTAAGTCAGAGGTGCCTCCACCCACATGATGGACTCACCTGCAGCCATTCAGAAGGAGGACGGGCAAACCGCACAGTGGCACGGAAAGA
CAAGGATGATGGCCGCGAAGTGGGGGCAGCATCCGATCCACATTCTAAAAGTAGCATAATCACCATTACTAAACACTAAAAAAAGGAAAA

>84404_84404_4_SNAP23-EIF2B5_SNAP23_chr15_42805645_ENST00000349777_EIF2B5_chr3_183859713_ENST00000444495_length(amino acids)=369AA_BP=49
MDNLSSEEIQQRAHQITDESLESTRRILGLAIESQDAGIKTITMLDEQKGDNVVLDQTYLWQGVRVAAGAQIHQSLLCDNAEVKERVTLK
PRSVLTSQVVVGPNITLPEGSVISLHPPDAEEDEDDGEFSDDSGADQEKDKVKMKGYNPAEVGAAGKGYLWKAAGMNMEEEEELQQNLWG
LKINMEEESESESEQSMDSEEPDSRGGSPQMDDIKVFQNEVLGTLQRGKEENISCDNLVLEINSLKYAYNISLKEVMQVLSHVVLEFPLQ
QMDSPLDSSRYCALLLPLLKAWSPVFRNYIKRAADHLEALAAIEDFFLEHEALGISMAKVLMAFYQLEILAEETILSWFSQRDTTDKGQQ

--------------------------------------------------------------
>84404_84404_5_SNAP23-EIF2B5_SNAP23_chr15_42805645_ENST00000397138_EIF2B5_chr3_183859713_ENST00000273783_length(transcript)=1525nt_BP=148nt
ATGGATAATCTGTCATCAGAAGAAATTCAACAGAGAGCTCACCAGATTACTGATGAGTCTCTGGAAAGTACGAGGAGAATCCTGGGTTTA
GCCATTGAGTCTCAGGATGCAGGAATCAAGACCATCACTATGCTGGATGAACAAAAGGGTGATAACGTGGTGCTGGACCAGACCTACCTG
TGGCAGGGTGTTCGAGTGGCGGCTGGAGCACAGATCCATCAGTCTCTGCTTTGTGACAATGCTGAGGTCAAGGAACGAGTGACACTGAAA
CCACGCTCTGTCCTCACTTCCCAGGTGGTCGTGGGCCCAAATATCACGCTGCCTGAGGGCTCGGTGATCTCTTTGCACCCTCCAGATGCA
GAGGAAGATGAAGATGATGGCGAGTTCAGTGATGATTCTGGGGCTGACCAAGAAAAGGACAAAGTGAAGATGAAAGGTTACAATCCAGCA
GAAGTAGGAGCTGCTGGCAAGGGCTACCTCTGGAAAGCTGCAGGCATGAACATGGAGGAAGAGGAGGAACTGCAGCAGAATCTGTGGGGA
CTCAAGATCAACATGGAAGAAGAGAGTGAAAGTGAAAGTGAGCAAAGTATGGATTCTGAGGAGCCGGACAGCCGGGGAGGCTCCCCTCAG
ATGGATGACATCAAAGTGTTCCAGAATGAAGTTTTAGGAACACTACAGCGGGGCAAAGAGGAGAACATTTCTTGTGACAATCTCGTCCTG
GAAATCAACTCTCTCAAGTATGCCTATAACATAAGTCTAAAGGAGGTGATGCAGGTACTGAGCCACGTGGTCCTGGAGTTCCCCCTGCAA
CAGATGGATTCCCCGCTTGACTCAAGCCGCTACTGTGCCCTGCTGCTTCCTCTGCTAAAGGCCTGGAGCCCTGTTTTTAGGAACTACATA
AAGCGCGCAGCCGACCATTTGGAAGCGTTAGCAGCCATTGAGGACTTCTTCCTAGAGCATGAAGCTCTTGGTATTTCCATGGCCAAGGTA
CTGATGGCTTTCTACCAGCTGGAGATCCTGGCTGAGGAAACAATTCTGAGCTGGTTCAGCCAAAGAGATACAACTGACAAGGGCCAGCAG
TTGCGCAAGAATCAACAGCTGCAGAGGTTCATCCAGTGGCTAAAAGAGGCAGAAGAGGAGTCATCTGAAGATGACTGAAGTCACACTGCC
TGCTCCTTTGGGTGTGATTGAGTGCCCTCCTGGCTCCTGGGCTGGGACAAGTGAGGAACTAGCTGCAGAGGGATGAGTGACCACCATCCA
GGCTGAGACTGAAAGGAGCAGAGGCTGGAACTACAGTATTCTTTCCCCTGCTAGCAACCATGTGCCTCCCATCCTGACTGTGGAGTTGGG
ATGTGGAAGTGGGGCTGGAACAAAGCTTCTGCCTAGGGAGGAGCTAAGCAGGCCCGGCAGTTGGAGGAAGGCCAGAGGAACAGCTTTGTG

>84404_84404_5_SNAP23-EIF2B5_SNAP23_chr15_42805645_ENST00000397138_EIF2B5_chr3_183859713_ENST00000273783_length(amino acids)=385AA_BP=49
MDNLSSEEIQQRAHQITDESLESTRRILGLAIESQDAGIKTITMLDEQKGDNVVLDQTYLWQGVRVAAGAQIHQSLLCDNAEVKERVTLK
PRSVLTSQVVVGPNITLPEGSVISLHPPDAEEDEDDGEFSDDSGADQEKDKVKMKGYNPAEVGAAGKGYLWKAAGMNMEEEEELQQNLWG
LKINMEEESESESEQSMDSEEPDSRGGSPQMDDIKVFQNEVLGTLQRGKEENISCDNLVLEINSLKYAYNISLKEVMQVLSHVVLEFPLQ
QMDSPLDSSRYCALLLPLLKAWSPVFRNYIKRAADHLEALAAIEDFFLEHEALGISMAKVLMAFYQLEILAEETILSWFSQRDTTDKGQQ

--------------------------------------------------------------
>84404_84404_6_SNAP23-EIF2B5_SNAP23_chr15_42805645_ENST00000397138_EIF2B5_chr3_183859713_ENST00000444495_length(transcript)=1371nt_BP=148nt
ATGGATAATCTGTCATCAGAAGAAATTCAACAGAGAGCTCACCAGATTACTGATGAGTCTCTGGAAAGTACGAGGAGAATCCTGGGTTTA
GCCATTGAGTCTCAGGATGCAGGAATCAAGACCATCACTATGCTGGATGAACAAAAGGGTGATAACGTGGTGCTGGACCAGACCTACCTG
TGGCAGGGTGTTCGAGTGGCGGCTGGAGCACAGATCCATCAGTCTCTGCTTTGTGACAATGCTGAGGTCAAGGAACGAGTGACACTGAAA
CCACGCTCTGTCCTCACTTCCCAGGTGGTCGTGGGCCCAAATATCACGCTGCCTGAGGGCTCGGTGATCTCTTTGCACCCTCCAGATGCA
GAGGAAGATGAAGATGATGGCGAGTTCAGTGATGATTCTGGGGCTGACCAAGAAAAGGACAAAGTGAAGATGAAAGGTTACAATCCAGCA
GAAGTAGGAGCTGCTGGCAAGGGCTACCTCTGGAAAGCTGCAGGCATGAACATGGAGGAAGAGGAGGAACTGCAGCAGAATCTGTGGGGA
CTCAAGATCAACATGGAAGAAGAGAGTGAAAGTGAAAGTGAGCAAAGTATGGATTCTGAGGAGCCGGACAGCCGGGGAGGCTCCCCTCAG
ATGGATGACATCAAAGTGTTCCAGAATGAAGTTTTAGGAACACTACAGCGGGGCAAAGAGGAGAACATTTCTTGTGACAATCTCGTCCTG
GAAATCAACTCTCTCAAGTATGCCTATAACATAAGTCTAAAGGAGGTGATGCAGGTACTGAGCCACGTGGTCCTGGAGTTCCCCCTGCAA
CAGATGGATTCCCCGCTTGACTCAAGCCGCTACTGTGCCCTGCTGCTTCCTCTGCTAAAGGCCTGGAGCCCTGTTTTTAGGAACTACATA
AAGCGCGCAGCCGACCATTTGGAAGCGTTAGCAGCCATTGAGGACTTCTTCCTAGAGCATGAAGCTCTTGGTATTTCCATGGCCAAGGTA
CTGATGGCTTTCTACCAGCTGGAGATCCTGGCTGAGGAAACAATTCTGAGCTGGTTCAGCCAAAGAGATACAACTGACAAGGGCCAGCAG
TTGCGCAAGAATCAACAGGTGGTGTGTTAAAGGCTTGACTAAACGGGATTCAGTTTTTCTACTTTTGTAAGACTTCAAATACAAATGTTC
TTAAGTCAGAGGTGCCTCCACCCACATGATGGACTCACCTGCAGCCATTCAGAAGGAGGACGGGCAAACCGCACAGTGGCACGGAAAGAC
AAGGATGATGGCCGCGAAGTGGGGGCAGCATCCGATCCACATTCTAAAAGTAGCATAATCACCATTACTAAACACTAAAAAAAGGAAAAT

>84404_84404_6_SNAP23-EIF2B5_SNAP23_chr15_42805645_ENST00000397138_EIF2B5_chr3_183859713_ENST00000444495_length(amino acids)=369AA_BP=49
MDNLSSEEIQQRAHQITDESLESTRRILGLAIESQDAGIKTITMLDEQKGDNVVLDQTYLWQGVRVAAGAQIHQSLLCDNAEVKERVTLK
PRSVLTSQVVVGPNITLPEGSVISLHPPDAEEDEDDGEFSDDSGADQEKDKVKMKGYNPAEVGAAGKGYLWKAAGMNMEEEEELQQNLWG
LKINMEEESESESEQSMDSEEPDSRGGSPQMDDIKVFQNEVLGTLQRGKEENISCDNLVLEINSLKYAYNISLKEVMQVLSHVVLEFPLQ
QMDSPLDSSRYCALLLPLLKAWSPVFRNYIKRAADHLEALAAIEDFFLEHEALGISMAKVLMAFYQLEILAEETILSWFSQRDTTDKGQQ

--------------------------------------------------------------
>84404_84404_7_SNAP23-EIF2B5_SNAP23_chr15_42805645_ENST00000564153_EIF2B5_chr3_183859713_ENST00000273783_length(transcript)=1619nt_BP=242nt
AGGCGCGACTAGGGTGCAGCGCCAGGTCCGGTGTTGGGGTGTCCGAGTTGCCGCCGGAGAGGAGTGGCCTCGCCCGCTTGAGTTTTGATT
CATCATGGATAATCTGTCATCAGAAGAAATTCAACAGAGAGCTCACCAGATTACTGATGAGTCTCTGGAAAGTACGAGGAGAATCCTGGG
TTTAGCCATTGAGTCTCAGGATGCAGGAATCAAGACCATCACTATGCTGGATGAACAAAAGGGTGATAACGTGGTGCTGGACCAGACCTA
CCTGTGGCAGGGTGTTCGAGTGGCGGCTGGAGCACAGATCCATCAGTCTCTGCTTTGTGACAATGCTGAGGTCAAGGAACGAGTGACACT
GAAACCACGCTCTGTCCTCACTTCCCAGGTGGTCGTGGGCCCAAATATCACGCTGCCTGAGGGCTCGGTGATCTCTTTGCACCCTCCAGA
TGCAGAGGAAGATGAAGATGATGGCGAGTTCAGTGATGATTCTGGGGCTGACCAAGAAAAGGACAAAGTGAAGATGAAAGGTTACAATCC
AGCAGAAGTAGGAGCTGCTGGCAAGGGCTACCTCTGGAAAGCTGCAGGCATGAACATGGAGGAAGAGGAGGAACTGCAGCAGAATCTGTG
GGGACTCAAGATCAACATGGAAGAAGAGAGTGAAAGTGAAAGTGAGCAAAGTATGGATTCTGAGGAGCCGGACAGCCGGGGAGGCTCCCC
TCAGATGGATGACATCAAAGTGTTCCAGAATGAAGTTTTAGGAACACTACAGCGGGGCAAAGAGGAGAACATTTCTTGTGACAATCTCGT
CCTGGAAATCAACTCTCTCAAGTATGCCTATAACATAAGTCTAAAGGAGGTGATGCAGGTACTGAGCCACGTGGTCCTGGAGTTCCCCCT
GCAACAGATGGATTCCCCGCTTGACTCAAGCCGCTACTGTGCCCTGCTGCTTCCTCTGCTAAAGGCCTGGAGCCCTGTTTTTAGGAACTA
CATAAAGCGCGCAGCCGACCATTTGGAAGCGTTAGCAGCCATTGAGGACTTCTTCCTAGAGCATGAAGCTCTTGGTATTTCCATGGCCAA
GGTACTGATGGCTTTCTACCAGCTGGAGATCCTGGCTGAGGAAACAATTCTGAGCTGGTTCAGCCAAAGAGATACAACTGACAAGGGCCA
GCAGTTGCGCAAGAATCAACAGCTGCAGAGGTTCATCCAGTGGCTAAAAGAGGCAGAAGAGGAGTCATCTGAAGATGACTGAAGTCACAC
TGCCTGCTCCTTTGGGTGTGATTGAGTGCCCTCCTGGCTCCTGGGCTGGGACAAGTGAGGAACTAGCTGCAGAGGGATGAGTGACCACCA
TCCAGGCTGAGACTGAAAGGAGCAGAGGCTGGAACTACAGTATTCTTTCCCCTGCTAGCAACCATGTGCCTCCCATCCTGACTGTGGAGT
TGGGATGTGGAAGTGGGGCTGGAACAAAGCTTCTGCCTAGGGAGGAGCTAAGCAGGCCCGGCAGTTGGAGGAAGGCCAGAGGAACAGCTT

>84404_84404_7_SNAP23-EIF2B5_SNAP23_chr15_42805645_ENST00000564153_EIF2B5_chr3_183859713_ENST00000273783_length(amino acids)=385AA_BP=49
MDNLSSEEIQQRAHQITDESLESTRRILGLAIESQDAGIKTITMLDEQKGDNVVLDQTYLWQGVRVAAGAQIHQSLLCDNAEVKERVTLK
PRSVLTSQVVVGPNITLPEGSVISLHPPDAEEDEDDGEFSDDSGADQEKDKVKMKGYNPAEVGAAGKGYLWKAAGMNMEEEEELQQNLWG
LKINMEEESESESEQSMDSEEPDSRGGSPQMDDIKVFQNEVLGTLQRGKEENISCDNLVLEINSLKYAYNISLKEVMQVLSHVVLEFPLQ
QMDSPLDSSRYCALLLPLLKAWSPVFRNYIKRAADHLEALAAIEDFFLEHEALGISMAKVLMAFYQLEILAEETILSWFSQRDTTDKGQQ

--------------------------------------------------------------
>84404_84404_8_SNAP23-EIF2B5_SNAP23_chr15_42805645_ENST00000564153_EIF2B5_chr3_183859713_ENST00000444495_length(transcript)=1465nt_BP=242nt
AGGCGCGACTAGGGTGCAGCGCCAGGTCCGGTGTTGGGGTGTCCGAGTTGCCGCCGGAGAGGAGTGGCCTCGCCCGCTTGAGTTTTGATT
CATCATGGATAATCTGTCATCAGAAGAAATTCAACAGAGAGCTCACCAGATTACTGATGAGTCTCTGGAAAGTACGAGGAGAATCCTGGG
TTTAGCCATTGAGTCTCAGGATGCAGGAATCAAGACCATCACTATGCTGGATGAACAAAAGGGTGATAACGTGGTGCTGGACCAGACCTA
CCTGTGGCAGGGTGTTCGAGTGGCGGCTGGAGCACAGATCCATCAGTCTCTGCTTTGTGACAATGCTGAGGTCAAGGAACGAGTGACACT
GAAACCACGCTCTGTCCTCACTTCCCAGGTGGTCGTGGGCCCAAATATCACGCTGCCTGAGGGCTCGGTGATCTCTTTGCACCCTCCAGA
TGCAGAGGAAGATGAAGATGATGGCGAGTTCAGTGATGATTCTGGGGCTGACCAAGAAAAGGACAAAGTGAAGATGAAAGGTTACAATCC
AGCAGAAGTAGGAGCTGCTGGCAAGGGCTACCTCTGGAAAGCTGCAGGCATGAACATGGAGGAAGAGGAGGAACTGCAGCAGAATCTGTG
GGGACTCAAGATCAACATGGAAGAAGAGAGTGAAAGTGAAAGTGAGCAAAGTATGGATTCTGAGGAGCCGGACAGCCGGGGAGGCTCCCC
TCAGATGGATGACATCAAAGTGTTCCAGAATGAAGTTTTAGGAACACTACAGCGGGGCAAAGAGGAGAACATTTCTTGTGACAATCTCGT
CCTGGAAATCAACTCTCTCAAGTATGCCTATAACATAAGTCTAAAGGAGGTGATGCAGGTACTGAGCCACGTGGTCCTGGAGTTCCCCCT
GCAACAGATGGATTCCCCGCTTGACTCAAGCCGCTACTGTGCCCTGCTGCTTCCTCTGCTAAAGGCCTGGAGCCCTGTTTTTAGGAACTA
CATAAAGCGCGCAGCCGACCATTTGGAAGCGTTAGCAGCCATTGAGGACTTCTTCCTAGAGCATGAAGCTCTTGGTATTTCCATGGCCAA
GGTACTGATGGCTTTCTACCAGCTGGAGATCCTGGCTGAGGAAACAATTCTGAGCTGGTTCAGCCAAAGAGATACAACTGACAAGGGCCA
GCAGTTGCGCAAGAATCAACAGGTGGTGTGTTAAAGGCTTGACTAAACGGGATTCAGTTTTTCTACTTTTGTAAGACTTCAAATACAAAT
GTTCTTAAGTCAGAGGTGCCTCCACCCACATGATGGACTCACCTGCAGCCATTCAGAAGGAGGACGGGCAAACCGCACAGTGGCACGGAA
AGACAAGGATGATGGCCGCGAAGTGGGGGCAGCATCCGATCCACATTCTAAAAGTAGCATAATCACCATTACTAAACACTAAAAAAAGGA

>84404_84404_8_SNAP23-EIF2B5_SNAP23_chr15_42805645_ENST00000564153_EIF2B5_chr3_183859713_ENST00000444495_length(amino acids)=369AA_BP=49
MDNLSSEEIQQRAHQITDESLESTRRILGLAIESQDAGIKTITMLDEQKGDNVVLDQTYLWQGVRVAAGAQIHQSLLCDNAEVKERVTLK
PRSVLTSQVVVGPNITLPEGSVISLHPPDAEEDEDDGEFSDDSGADQEKDKVKMKGYNPAEVGAAGKGYLWKAAGMNMEEEEELQQNLWG
LKINMEEESESESEQSMDSEEPDSRGGSPQMDDIKVFQNEVLGTLQRGKEENISCDNLVLEINSLKYAYNISLKEVMQVLSHVVLEFPLQ
QMDSPLDSSRYCALLLPLLKAWSPVFRNYIKRAADHLEALAAIEDFFLEHEALGISMAKVLMAFYQLEILAEETILSWFSQRDTTDKGQQ

--------------------------------------------------------------
>84404_84404_9_SNAP23-EIF2B5_SNAP23_chr15_42805645_ENST00000567094_EIF2B5_chr3_183859713_ENST00000273783_length(transcript)=1611nt_BP=234nt
CTAGGGTGCAGCGCCAGGTCCGGTGTTGGGGTGTCCGAGTTGCCGCCGGAGAGGAGTGGCCTCGCCCGCTTGAGTTTTGATTCATCATGG
ATAATCTGTCATCAGAAGAAATTCAACAGAGAGCTCACCAGATTACTGATGAGTCTCTGGAAAGTACGAGGAGAATCCTGGGTTTAGCCA
TTGAGTCTCAGGATGCAGGAATCAAGACCATCACTATGCTGGATGAACAAAAGGGTGATAACGTGGTGCTGGACCAGACCTACCTGTGGC
AGGGTGTTCGAGTGGCGGCTGGAGCACAGATCCATCAGTCTCTGCTTTGTGACAATGCTGAGGTCAAGGAACGAGTGACACTGAAACCAC
GCTCTGTCCTCACTTCCCAGGTGGTCGTGGGCCCAAATATCACGCTGCCTGAGGGCTCGGTGATCTCTTTGCACCCTCCAGATGCAGAGG
AAGATGAAGATGATGGCGAGTTCAGTGATGATTCTGGGGCTGACCAAGAAAAGGACAAAGTGAAGATGAAAGGTTACAATCCAGCAGAAG
TAGGAGCTGCTGGCAAGGGCTACCTCTGGAAAGCTGCAGGCATGAACATGGAGGAAGAGGAGGAACTGCAGCAGAATCTGTGGGGACTCA
AGATCAACATGGAAGAAGAGAGTGAAAGTGAAAGTGAGCAAAGTATGGATTCTGAGGAGCCGGACAGCCGGGGAGGCTCCCCTCAGATGG
ATGACATCAAAGTGTTCCAGAATGAAGTTTTAGGAACACTACAGCGGGGCAAAGAGGAGAACATTTCTTGTGACAATCTCGTCCTGGAAA
TCAACTCTCTCAAGTATGCCTATAACATAAGTCTAAAGGAGGTGATGCAGGTACTGAGCCACGTGGTCCTGGAGTTCCCCCTGCAACAGA
TGGATTCCCCGCTTGACTCAAGCCGCTACTGTGCCCTGCTGCTTCCTCTGCTAAAGGCCTGGAGCCCTGTTTTTAGGAACTACATAAAGC
GCGCAGCCGACCATTTGGAAGCGTTAGCAGCCATTGAGGACTTCTTCCTAGAGCATGAAGCTCTTGGTATTTCCATGGCCAAGGTACTGA
TGGCTTTCTACCAGCTGGAGATCCTGGCTGAGGAAACAATTCTGAGCTGGTTCAGCCAAAGAGATACAACTGACAAGGGCCAGCAGTTGC
GCAAGAATCAACAGCTGCAGAGGTTCATCCAGTGGCTAAAAGAGGCAGAAGAGGAGTCATCTGAAGATGACTGAAGTCACACTGCCTGCT
CCTTTGGGTGTGATTGAGTGCCCTCCTGGCTCCTGGGCTGGGACAAGTGAGGAACTAGCTGCAGAGGGATGAGTGACCACCATCCAGGCT
GAGACTGAAAGGAGCAGAGGCTGGAACTACAGTATTCTTTCCCCTGCTAGCAACCATGTGCCTCCCATCCTGACTGTGGAGTTGGGATGT
GGAAGTGGGGCTGGAACAAAGCTTCTGCCTAGGGAGGAGCTAAGCAGGCCCGGCAGTTGGAGGAAGGCCAGAGGAACAGCTTTGTGCTCC

>84404_84404_9_SNAP23-EIF2B5_SNAP23_chr15_42805645_ENST00000567094_EIF2B5_chr3_183859713_ENST00000273783_length(amino acids)=385AA_BP=49
MDNLSSEEIQQRAHQITDESLESTRRILGLAIESQDAGIKTITMLDEQKGDNVVLDQTYLWQGVRVAAGAQIHQSLLCDNAEVKERVTLK
PRSVLTSQVVVGPNITLPEGSVISLHPPDAEEDEDDGEFSDDSGADQEKDKVKMKGYNPAEVGAAGKGYLWKAAGMNMEEEEELQQNLWG
LKINMEEESESESEQSMDSEEPDSRGGSPQMDDIKVFQNEVLGTLQRGKEENISCDNLVLEINSLKYAYNISLKEVMQVLSHVVLEFPLQ
QMDSPLDSSRYCALLLPLLKAWSPVFRNYIKRAADHLEALAAIEDFFLEHEALGISMAKVLMAFYQLEILAEETILSWFSQRDTTDKGQQ

--------------------------------------------------------------
>84404_84404_10_SNAP23-EIF2B5_SNAP23_chr15_42805645_ENST00000567094_EIF2B5_chr3_183859713_ENST00000444495_length(transcript)=1457nt_BP=234nt
CTAGGGTGCAGCGCCAGGTCCGGTGTTGGGGTGTCCGAGTTGCCGCCGGAGAGGAGTGGCCTCGCCCGCTTGAGTTTTGATTCATCATGG
ATAATCTGTCATCAGAAGAAATTCAACAGAGAGCTCACCAGATTACTGATGAGTCTCTGGAAAGTACGAGGAGAATCCTGGGTTTAGCCA
TTGAGTCTCAGGATGCAGGAATCAAGACCATCACTATGCTGGATGAACAAAAGGGTGATAACGTGGTGCTGGACCAGACCTACCTGTGGC
AGGGTGTTCGAGTGGCGGCTGGAGCACAGATCCATCAGTCTCTGCTTTGTGACAATGCTGAGGTCAAGGAACGAGTGACACTGAAACCAC
GCTCTGTCCTCACTTCCCAGGTGGTCGTGGGCCCAAATATCACGCTGCCTGAGGGCTCGGTGATCTCTTTGCACCCTCCAGATGCAGAGG
AAGATGAAGATGATGGCGAGTTCAGTGATGATTCTGGGGCTGACCAAGAAAAGGACAAAGTGAAGATGAAAGGTTACAATCCAGCAGAAG
TAGGAGCTGCTGGCAAGGGCTACCTCTGGAAAGCTGCAGGCATGAACATGGAGGAAGAGGAGGAACTGCAGCAGAATCTGTGGGGACTCA
AGATCAACATGGAAGAAGAGAGTGAAAGTGAAAGTGAGCAAAGTATGGATTCTGAGGAGCCGGACAGCCGGGGAGGCTCCCCTCAGATGG
ATGACATCAAAGTGTTCCAGAATGAAGTTTTAGGAACACTACAGCGGGGCAAAGAGGAGAACATTTCTTGTGACAATCTCGTCCTGGAAA
TCAACTCTCTCAAGTATGCCTATAACATAAGTCTAAAGGAGGTGATGCAGGTACTGAGCCACGTGGTCCTGGAGTTCCCCCTGCAACAGA
TGGATTCCCCGCTTGACTCAAGCCGCTACTGTGCCCTGCTGCTTCCTCTGCTAAAGGCCTGGAGCCCTGTTTTTAGGAACTACATAAAGC
GCGCAGCCGACCATTTGGAAGCGTTAGCAGCCATTGAGGACTTCTTCCTAGAGCATGAAGCTCTTGGTATTTCCATGGCCAAGGTACTGA
TGGCTTTCTACCAGCTGGAGATCCTGGCTGAGGAAACAATTCTGAGCTGGTTCAGCCAAAGAGATACAACTGACAAGGGCCAGCAGTTGC
GCAAGAATCAACAGGTGGTGTGTTAAAGGCTTGACTAAACGGGATTCAGTTTTTCTACTTTTGTAAGACTTCAAATACAAATGTTCTTAA
GTCAGAGGTGCCTCCACCCACATGATGGACTCACCTGCAGCCATTCAGAAGGAGGACGGGCAAACCGCACAGTGGCACGGAAAGACAAGG
ATGATGGCCGCGAAGTGGGGGCAGCATCCGATCCACATTCTAAAAGTAGCATAATCACCATTACTAAACACTAAAAAAAGGAAAATAAAG

>84404_84404_10_SNAP23-EIF2B5_SNAP23_chr15_42805645_ENST00000567094_EIF2B5_chr3_183859713_ENST00000444495_length(amino acids)=369AA_BP=49
MDNLSSEEIQQRAHQITDESLESTRRILGLAIESQDAGIKTITMLDEQKGDNVVLDQTYLWQGVRVAAGAQIHQSLLCDNAEVKERVTLK
PRSVLTSQVVVGPNITLPEGSVISLHPPDAEEDEDDGEFSDDSGADQEKDKVKMKGYNPAEVGAAGKGYLWKAAGMNMEEEEELQQNLWG
LKINMEEESESESEQSMDSEEPDSRGGSPQMDDIKVFQNEVLGTLQRGKEENISCDNLVLEINSLKYAYNISLKEVMQVLSHVVLEFPLQ
QMDSPLDSSRYCALLLPLLKAWSPVFRNYIKRAADHLEALAAIEDFFLEHEALGISMAKVLMAFYQLEILAEETILSWFSQRDTTDKGQQ

--------------------------------------------------------------

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Fusion Gene PPI Analysis for SNAP23-EIF2B5


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for SNAP23-EIF2B5


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for SNAP23-EIF2B5


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource