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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:SNCAIP-COMMD10 (FusionGDB2 ID:84452)

Fusion Gene Summary for SNCAIP-COMMD10

check button Fusion gene summary
Fusion gene informationFusion gene name: SNCAIP-COMMD10
Fusion gene ID: 84452
HgeneTgene
Gene symbol

SNCAIP

COMMD10

Gene ID

9627

51397

Gene namesynuclein alpha interacting proteinCOMM domain containing 10
SynonymsSYPH1|Sph1PTD002
Cytomap

5q23.2

5q23.1

Type of geneprotein-codingprotein-coding
Descriptionsynphilin-1COMM domain-containing protein 10
Modification date2020031320200313
UniProtAcc.

Q9Y6G5

Ensembl transtripts involved in fusion geneENST00000261367, ENST00000261368, 
ENST00000379533, ENST00000379536, 
ENST00000379538, ENST00000414317, 
ENST00000503116, ENST00000504884, 
ENST00000542191, 		ENST00000503424, 
ENST00000274458, ENST00000515539, 
Fusion gene scores* DoF score9 X 6 X 4=21614 X 11 X 6=924
# samples 914
** MAII scorelog2(9/216*10)=-1.26303440583379
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(14/924*10)=-2.72246602447109
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: SNCAIP [Title/Abstract] AND COMMD10 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointSNCAIP(121726886)-COMMD10(115469765), # samples:1
Anticipated loss of major functional domain due to fusion event.SNCAIP-COMMD10 seems lost the major protein functional domain in Tgene partner, which is a essential gene due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneSNCAIP

GO:0008219

cell death

16595633

HgeneSNCAIP

GO:0042417

dopamine metabolic process

14506261

HgeneSNCAIP

GO:0046928

regulation of neurotransmitter secretion

14506261

HgeneSNCAIP

GO:0090083

regulation of inclusion body assembly

15603737


check buttonFusion gene breakpoints across SNCAIP (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across COMMD10 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4STADTCGA-CD-8525-01ASNCAIPchr5

121726886

+COMMD10chr5

115469765

+


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Fusion Gene ORF analysis for SNCAIP-COMMD10

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000261367ENST00000503424SNCAIPchr5

121726886

+COMMD10chr5

115469765

+
5CDS-intronENST00000261368ENST00000503424SNCAIPchr5

121726886

+COMMD10chr5

115469765

+
5CDS-intronENST00000379533ENST00000503424SNCAIPchr5

121726886

+COMMD10chr5

115469765

+
5CDS-intronENST00000379536ENST00000503424SNCAIPchr5

121726886

+COMMD10chr5

115469765

+
5CDS-intronENST00000379538ENST00000503424SNCAIPchr5

121726886

+COMMD10chr5

115469765

+
5CDS-intronENST00000414317ENST00000503424SNCAIPchr5

121726886

+COMMD10chr5

115469765

+
5CDS-intronENST00000503116ENST00000503424SNCAIPchr5

121726886

+COMMD10chr5

115469765

+
5CDS-intronENST00000504884ENST00000503424SNCAIPchr5

121726886

+COMMD10chr5

115469765

+
5UTR-3CDSENST00000542191ENST00000274458SNCAIPchr5

121726886

+COMMD10chr5

115469765

+
5UTR-3CDSENST00000542191ENST00000515539SNCAIPchr5

121726886

+COMMD10chr5

115469765

+
5UTR-intronENST00000542191ENST00000503424SNCAIPchr5

121726886

+COMMD10chr5

115469765

+
Frame-shiftENST00000379538ENST00000274458SNCAIPchr5

121726886

+COMMD10chr5

115469765

+
Frame-shiftENST00000379538ENST00000515539SNCAIPchr5

121726886

+COMMD10chr5

115469765

+
Frame-shiftENST00000414317ENST00000274458SNCAIPchr5

121726886

+COMMD10chr5

115469765

+
Frame-shiftENST00000414317ENST00000515539SNCAIPchr5

121726886

+COMMD10chr5

115469765

+
In-frameENST00000261367ENST00000274458SNCAIPchr5

121726886

+COMMD10chr5

115469765

+
In-frameENST00000261367ENST00000515539SNCAIPchr5

121726886

+COMMD10chr5

115469765

+
In-frameENST00000261368ENST00000274458SNCAIPchr5

121726886

+COMMD10chr5

115469765

+
In-frameENST00000261368ENST00000515539SNCAIPchr5

121726886

+COMMD10chr5

115469765

+
In-frameENST00000379533ENST00000274458SNCAIPchr5

121726886

+COMMD10chr5

115469765

+
In-frameENST00000379533ENST00000515539SNCAIPchr5

121726886

+COMMD10chr5

115469765

+
In-frameENST00000379536ENST00000274458SNCAIPchr5

121726886

+COMMD10chr5

115469765

+
In-frameENST00000379536ENST00000515539SNCAIPchr5

121726886

+COMMD10chr5

115469765

+
In-frameENST00000503116ENST00000274458SNCAIPchr5

121726886

+COMMD10chr5

115469765

+
In-frameENST00000503116ENST00000515539SNCAIPchr5

121726886

+COMMD10chr5

115469765

+
In-frameENST00000504884ENST00000274458SNCAIPchr5

121726886

+COMMD10chr5

115469765

+
In-frameENST00000504884ENST00000515539SNCAIPchr5

121726886

+COMMD10chr5

115469765

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000261368SNCAIPchr5121726886+ENST00000274458COMMD10chr5115469765+13273191065748105
ENST00000261368SNCAIPchr5121726886+ENST00000515539COMMD10chr5115469765+69731926252888
ENST00000379533SNCAIPchr5121726886+ENST00000274458COMMD10chr5115469765+12712631009692105
ENST00000379533SNCAIPchr5121726886+ENST00000515539COMMD10chr5115469765+64126320647288
ENST00000379536SNCAIPchr5121726886+ENST00000274458COMMD10chr5115469765+12712631009692105
ENST00000379536SNCAIPchr5121726886+ENST00000515539COMMD10chr5115469765+64126320647288
ENST00000261367SNCAIPchr5121726886+ENST00000274458COMMD10chr5115469765+2493148522311914105
ENST00000261367SNCAIPchr5121726886+ENST00000515539COMMD10chr5115469765+18631485606911101
ENST00000503116SNCAIPchr5121726886+ENST00000274458COMMD10chr5115469765+106557803486105
ENST00000503116SNCAIPchr5121726886+ENST00000515539COMMD10chr5115469765+43557026688
ENST00000504884SNCAIPchr5121726886+ENST00000274458COMMD10chr5115469765+106557803486105
ENST00000504884SNCAIPchr5121726886+ENST00000515539COMMD10chr5115469765+43557026688

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000261368ENST00000274458SNCAIPchr5121726886+COMMD10chr5115469765+0.0157512970.9842487
ENST00000261368ENST00000515539SNCAIPchr5121726886+COMMD10chr5115469765+0.0161100090.98389006
ENST00000379533ENST00000274458SNCAIPchr5121726886+COMMD10chr5115469765+0.0149573530.9850426
ENST00000379533ENST00000515539SNCAIPchr5121726886+COMMD10chr5115469765+0.0113378240.9886622
ENST00000379536ENST00000274458SNCAIPchr5121726886+COMMD10chr5115469765+0.0149573530.9850426
ENST00000379536ENST00000515539SNCAIPchr5121726886+COMMD10chr5115469765+0.0113378240.9886622
ENST00000261367ENST00000274458SNCAIPchr5121726886+COMMD10chr5115469765+0.65394890.3460511
ENST00000261367ENST00000515539SNCAIPchr5121726886+COMMD10chr5115469765+0.24848790.7515121
ENST00000503116ENST00000274458SNCAIPchr5121726886+COMMD10chr5115469765+0.0296760830.97032386
ENST00000503116ENST00000515539SNCAIPchr5121726886+COMMD10chr5115469765+0.0141887650.98581123
ENST00000504884ENST00000274458SNCAIPchr5121726886+COMMD10chr5115469765+0.0296760830.97032386
ENST00000504884ENST00000515539SNCAIPchr5121726886+COMMD10chr5115469765+0.0141887650.98581123

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Fusion Genomic Features for SNCAIP-COMMD10


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
SNCAIPchr5121726886+COMMD10chr5115469764+0.80549340.19450662
SNCAIPchr5121726886+COMMD10chr5115469764+0.80549340.19450662

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for SNCAIP-COMMD10


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr5:121726886/chr5:115469765)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
.COMMD10

Q9Y6G5

FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: May modulate activity of cullin-RING E3 ubiquitin ligase (CRL) complexes (PubMed:21778237). May down-regulate activation of NF-kappa-B (PubMed:15799966). {ECO:0000269|PubMed:15799966, ECO:0000305|PubMed:21778237}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneCOMMD10chr5:121726886chr5:115469765ENST0000027445837133_202133203.0DomainCOMM

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneSNCAIPchr5:121726886chr5:115469765ENST00000261367+314515_552191017.0Coiled coilOntology_term=ECO:0000255
HgeneSNCAIPchr5:121726886chr5:115469765ENST00000261368+211515_55219920.0Coiled coilOntology_term=ECO:0000255
HgeneSNCAIPchr5:121726886chr5:115469765ENST00000379533+213515_552191017.0Coiled coilOntology_term=ECO:0000255
HgeneSNCAIPchr5:121726886chr5:115469765ENST00000379536+210515_55219860.0Coiled coilOntology_term=ECO:0000255
HgeneSNCAIPchr5:121726886chr5:115469765ENST00000379538+210515_5523604.0Coiled coilOntology_term=ECO:0000255
HgeneSNCAIPchr5:121726886chr5:115469765ENST00000503116+112515_55219943.6666666666666Coiled coilOntology_term=ECO:0000255
HgeneSNCAIPchr5:121726886chr5:115469765ENST00000261367+314349_380191017.0RepeatNote=ANK 1
HgeneSNCAIPchr5:121726886chr5:115469765ENST00000261367+314384_413191017.0RepeatNote=ANK 2
HgeneSNCAIPchr5:121726886chr5:115469765ENST00000261367+314419_448191017.0RepeatNote=ANK 3
HgeneSNCAIPchr5:121726886chr5:115469765ENST00000261367+314456_485191017.0RepeatNote=ANK 4
HgeneSNCAIPchr5:121726886chr5:115469765ENST00000261367+314603_632191017.0RepeatNote=ANK 5
HgeneSNCAIPchr5:121726886chr5:115469765ENST00000261367+314699_729191017.0RepeatNote=ANK 6
HgeneSNCAIPchr5:121726886chr5:115469765ENST00000261368+211349_38019920.0RepeatNote=ANK 1
HgeneSNCAIPchr5:121726886chr5:115469765ENST00000261368+211384_41319920.0RepeatNote=ANK 2
HgeneSNCAIPchr5:121726886chr5:115469765ENST00000261368+211419_44819920.0RepeatNote=ANK 3
HgeneSNCAIPchr5:121726886chr5:115469765ENST00000261368+211456_48519920.0RepeatNote=ANK 4
HgeneSNCAIPchr5:121726886chr5:115469765ENST00000261368+211603_63219920.0RepeatNote=ANK 5
HgeneSNCAIPchr5:121726886chr5:115469765ENST00000261368+211699_72919920.0RepeatNote=ANK 6
HgeneSNCAIPchr5:121726886chr5:115469765ENST00000379533+213349_380191017.0RepeatNote=ANK 1
HgeneSNCAIPchr5:121726886chr5:115469765ENST00000379533+213384_413191017.0RepeatNote=ANK 2
HgeneSNCAIPchr5:121726886chr5:115469765ENST00000379533+213419_448191017.0RepeatNote=ANK 3
HgeneSNCAIPchr5:121726886chr5:115469765ENST00000379533+213456_485191017.0RepeatNote=ANK 4
HgeneSNCAIPchr5:121726886chr5:115469765ENST00000379533+213603_632191017.0RepeatNote=ANK 5
HgeneSNCAIPchr5:121726886chr5:115469765ENST00000379533+213699_729191017.0RepeatNote=ANK 6
HgeneSNCAIPchr5:121726886chr5:115469765ENST00000379536+210349_38019860.0RepeatNote=ANK 1
HgeneSNCAIPchr5:121726886chr5:115469765ENST00000379536+210384_41319860.0RepeatNote=ANK 2
HgeneSNCAIPchr5:121726886chr5:115469765ENST00000379536+210419_44819860.0RepeatNote=ANK 3
HgeneSNCAIPchr5:121726886chr5:115469765ENST00000379536+210456_48519860.0RepeatNote=ANK 4
HgeneSNCAIPchr5:121726886chr5:115469765ENST00000379536+210603_63219860.0RepeatNote=ANK 5
HgeneSNCAIPchr5:121726886chr5:115469765ENST00000379536+210699_72919860.0RepeatNote=ANK 6
HgeneSNCAIPchr5:121726886chr5:115469765ENST00000379538+210349_3803604.0RepeatNote=ANK 1
HgeneSNCAIPchr5:121726886chr5:115469765ENST00000379538+210384_4133604.0RepeatNote=ANK 2
HgeneSNCAIPchr5:121726886chr5:115469765ENST00000379538+210419_4483604.0RepeatNote=ANK 3
HgeneSNCAIPchr5:121726886chr5:115469765ENST00000379538+210456_4853604.0RepeatNote=ANK 4
HgeneSNCAIPchr5:121726886chr5:115469765ENST00000379538+210603_6323604.0RepeatNote=ANK 5
HgeneSNCAIPchr5:121726886chr5:115469765ENST00000379538+210699_7293604.0RepeatNote=ANK 6
HgeneSNCAIPchr5:121726886chr5:115469765ENST00000503116+112349_38019943.6666666666666RepeatNote=ANK 1
HgeneSNCAIPchr5:121726886chr5:115469765ENST00000503116+112384_41319943.6666666666666RepeatNote=ANK 2
HgeneSNCAIPchr5:121726886chr5:115469765ENST00000503116+112419_44819943.6666666666666RepeatNote=ANK 3
HgeneSNCAIPchr5:121726886chr5:115469765ENST00000503116+112456_48519943.6666666666666RepeatNote=ANK 4
HgeneSNCAIPchr5:121726886chr5:115469765ENST00000503116+112603_63219943.6666666666666RepeatNote=ANK 5
HgeneSNCAIPchr5:121726886chr5:115469765ENST00000503116+112699_72919943.6666666666666RepeatNote=ANK 6


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Fusion Gene Sequence for SNCAIP-COMMD10


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>84452_84452_1_SNCAIP-COMMD10_SNCAIP_chr5_121726886_ENST00000261367_COMMD10_chr5_115469765_ENST00000274458_length(transcript)=2493nt_BP=1485nt
GCTCCTGCCGCTGCGGTCCGTCGGTCGGTCAGTCAGTCCCTTCGCGCTCCTGAGCCGCCGGCGCGCCGGGCGCCCCGGAAAAGAGTGCCT
GAGAGTGCCAGAGGCTTGGTGGAAGGGCAGACGAGAGAAGAGGAGGCATTGTATTGGCCACTGGGACAACTGCAGACTCACTCTTACCTG
TAAAGAAGCAGTTAATGTTGGGGAATGTAGTCAGGATTGGAAAACCACGGGGATTTCTGCACATTATAATTGAGAATGTAAATATTCTTA
AAGTGGCACCCTGAAAGAGACAAGCATTGAAACCAGACAAAATAAATTGGATCATGAACAGAATGAGACATCTTAAAGGAGATAGCATGT
GGAGGCCTGCTGGGAAGTAGAGGCAAATTCCAGATGCCTAGGAGCCTTAGTCTAAGGTGGGGCCATCCAACCCACAGAAATAAATATGGG
CAGTGGCCCAAGACTTCCTATAATGAGCTGCACCTGTTGTAAGTCTTGTGTTCTTGCCTATAGAATAAAGAACCTCACTACCATCCTGCA
AGTGCAAATTGAAAGATTCCTGTTGTGATGCCATGAGTTATTATCCGCTGGTTATATTCTATTGGAATGGCTACACTCAACTGGATATTG
CTGTCTATATTGTTGGAGCACCTCAAACAGGGGTGCAATGGTTATTTGTTAATTTACTTAATTAAGACATGTTCATCCACATTTTATAGT
TTCATTTATTTAAAGATCCATTTGGTCCCCAGCTTCGATGCATGTTTCTCTGCTTCATCTCCCCATATTTCCATGTTCCTGCTGATGTTT
ATACCATATCCTGGCACCCAGCATCATCTGTGTGTTGTTCACCAAGGCCGTGGGAACAGAGTCTGTAAATCAATAGTTCATCACGGAGTA
CAGATTTCATGAAAAGAAATTGGATTGGAAGAAAGTCTCCTAGTGAACACGCTAGTATCCAAAGAGTCTGGATTGTATCAGAATCCATCA
CAGTAGGAGAGAATGTTGTTTTGAGTAATTTCCAAGCAGAGTACATATATTTTCCTCTGAAAATCTTTGTAAATTGAAGAAAAGTGACAT
TTTTATACCAAGCAATTTGTTTGATAACCTATTTTCAGATTTCTACAAATAATAAAATTTCTGATTTTAAATATTTTTTACAAATACAAG
TTGGTTTTCTTTTCATTGTAAGCCTTACTGTGATTTCAGAAGAATTTTTAACATTTGCTAAATGGATAATCTCATTTAAACATGGAAGTA
ACATCCTAATCCTTTCTTGGATGGACTCTGTATCTATTGTAATTAAGACTTTAAAAATGGTATATACATATGGGAAAAAAAGGAGAGGAA
ACAGGAAAATTAAATCAAGTGATGGGTTTGAGGAATTTATAAGTATTTGACCGTACTCAAAATGTGCAAGGAAGAATAATGGAAGCCCCT
GAATACCTTGATTTGGATGAAATTGACTTTAGTGATGACATATCTCTAGAGACCGTTGGATGGCAGCTTAACCTTCAGATGGCTCACTCT
GCTCAAGCAAAACTAAAATCTCCTCAAGCTGTGTTACAACTCGGAGTGAACAATGAAGATTCAAAGAGCCTGGAGAAAGTTCTTGTGGAA
TTCAGTCACAAGGAGTTGTTTGATTTCTATAACAAGCTAGAGACTATACAAGCACAGCTGGATTCCCTTACATGATGTTTTCGAAGACTG
TTTTTTTCATCACGCTCCTGCCACCTCATTATTTTGCATTGAAGATACATTGCCAGGTTGTGTTTTCTGAAGGATTCAGTGACTTGCTTT
CTGTAAATTATATGGCTTATCACTTCTTAGACAAATAACAACCAATAGAGATCATTGTTAAGAATACTGAGGTTCTAATATACTTTCTTT
AGTTCTGTGAGCCAACAGTAATTATTAAGAACACTTTCCCTTTAAAGGAAACAAAAGTGAATACCATATTGTTTTTACTGTCATAGTGTT
GCTTTCTTGCCTGTCCTGCTTAGTTTTTACTTGCTGGATGATACCATAATGTATCAAGGAGCGTCCATGGATACAAGATAAGATGTGTAC
CTTAGTAGAATACAGAGCTTTGGTAATTACATGAATAAAATTAAGAAAATAGCCATATACAATCAAATACACTATGGCATTTTTATTTGA
ATATGATGAGTATATTTTGCTTCGGAAATAATATAGGAAGGAAATGTAAAATAGTGAGTAGTATGGTATCAGTTAATTCCAGTCTGAGCT
TCTCTGTCAACTTCAGTTTCTCTCTCAGTTTAATGATTTAATAATAGTCCAGGTTTTTGTGTGTTTTTCTTTATACTGCAAATTAATAAT
GATTCACTTTATAGTTTGGGAGACAGAATCAGGTCTTGAATAAAATAATTGTAATGAGTGCTAAATGGGCACCATTATTCGAATCAGATA

>84452_84452_1_SNCAIP-COMMD10_SNCAIP_chr5_121726886_ENST00000261367_COMMD10_chr5_115469765_ENST00000274458_length(amino acids)=105AA_BP=
MIPYYSLFYISFLYYFRSKIYSSYSNKNAIVYLIVYGYFLNFIHVITKALYSTKVHILSCIHGRSLIHYGIIQQVKTKQDRQESNTMTVK

--------------------------------------------------------------
>84452_84452_2_SNCAIP-COMMD10_SNCAIP_chr5_121726886_ENST00000261367_COMMD10_chr5_115469765_ENST00000515539_length(transcript)=1863nt_BP=1485nt
GCTCCTGCCGCTGCGGTCCGTCGGTCGGTCAGTCAGTCCCTTCGCGCTCCTGAGCCGCCGGCGCGCCGGGCGCCCCGGAAAAGAGTGCCT
GAGAGTGCCAGAGGCTTGGTGGAAGGGCAGACGAGAGAAGAGGAGGCATTGTATTGGCCACTGGGACAACTGCAGACTCACTCTTACCTG
TAAAGAAGCAGTTAATGTTGGGGAATGTAGTCAGGATTGGAAAACCACGGGGATTTCTGCACATTATAATTGAGAATGTAAATATTCTTA
AAGTGGCACCCTGAAAGAGACAAGCATTGAAACCAGACAAAATAAATTGGATCATGAACAGAATGAGACATCTTAAAGGAGATAGCATGT
GGAGGCCTGCTGGGAAGTAGAGGCAAATTCCAGATGCCTAGGAGCCTTAGTCTAAGGTGGGGCCATCCAACCCACAGAAATAAATATGGG
CAGTGGCCCAAGACTTCCTATAATGAGCTGCACCTGTTGTAAGTCTTGTGTTCTTGCCTATAGAATAAAGAACCTCACTACCATCCTGCA
AGTGCAAATTGAAAGATTCCTGTTGTGATGCCATGAGTTATTATCCGCTGGTTATATTCTATTGGAATGGCTACACTCAACTGGATATTG
CTGTCTATATTGTTGGAGCACCTCAAACAGGGGTGCAATGGTTATTTGTTAATTTACTTAATTAAGACATGTTCATCCACATTTTATAGT
TTCATTTATTTAAAGATCCATTTGGTCCCCAGCTTCGATGCATGTTTCTCTGCTTCATCTCCCCATATTTCCATGTTCCTGCTGATGTTT
ATACCATATCCTGGCACCCAGCATCATCTGTGTGTTGTTCACCAAGGCCGTGGGAACAGAGTCTGTAAATCAATAGTTCATCACGGAGTA
CAGATTTCATGAAAAGAAATTGGATTGGAAGAAAGTCTCCTAGTGAACACGCTAGTATCCAAAGAGTCTGGATTGTATCAGAATCCATCA
CAGTAGGAGAGAATGTTGTTTTGAGTAATTTCCAAGCAGAGTACATATATTTTCCTCTGAAAATCTTTGTAAATTGAAGAAAAGTGACAT
TTTTATACCAAGCAATTTGTTTGATAACCTATTTTCAGATTTCTACAAATAATAAAATTTCTGATTTTAAATATTTTTTACAAATACAAG
TTGGTTTTCTTTTCATTGTAAGCCTTACTGTGATTTCAGAAGAATTTTTAACATTTGCTAAATGGATAATCTCATTTAAACATGGAAGTA
ACATCCTAATCCTTTCTTGGATGGACTCTGTATCTATTGTAATTAAGACTTTAAAAATGGTATATACATATGGGAAAAAAAGGAGAGGAA
ACAGGAAAATTAAATCAAGTGATGGGTTTGAGGAATTTATAAGTATTTGACCGTACTCAAAATGTGCAAGGAAGAATAATGGAAGCCCCT
GAATACCTTGATTTGGATGAAATTGACTTTAGTGATGACATATCTCTAGAGACCGTTGGATGGCAGCTTAACCTTCAGATGGCTCACTCT
GCTCAAGCAAAACTAAAATCTCCTCAAGCTGTGTTACAACTCGGAGTGAACAATGAAGATTCAAAGAGCCTGGAGAAAGTTCTTGTGGAA
TTCAGTCACAAGGAGTTGTTTGATTTCTATAACAAGCTAGAGACTATACAAGCACAGCTGGATTCCCTTACATGATGTTTTCGAAGACTG
TTTTTTTCATCACGCTCCTGCCACCTCATTATTTTGCATTGAAGATACATTGCCAGGTTGTGTTTTCTGAAGGATTCAGTGACTTGCTTT

>84452_84452_2_SNCAIP-COMMD10_SNCAIP_chr5_121726886_ENST00000261367_COMMD10_chr5_115469765_ENST00000515539_length(amino acids)=101AA_BP=
MATLNWILLSILLEHLKQGCNGYLLIYLIKTCSSTFYSFIYLKIHLVPSFDACFSASSPHISMFLLMFIPYPGTQHHLCVVHQGRGNRVC

--------------------------------------------------------------
>84452_84452_3_SNCAIP-COMMD10_SNCAIP_chr5_121726886_ENST00000261368_COMMD10_chr5_115469765_ENST00000274458_length(transcript)=1327nt_BP=319nt
GCGGCCGCCCAGGCTGCCCCCGCCCGCGCGCGCCCGTTGGGGGGCCCGGGGAGCGGCGCCCGCGGCCGGGCCGCATTGTGACGTAGCGGG
GCCGCGGCAGCGCCTCCACCGCCCGCCTACTTCGGCTGAGGCTGTTCTGCTCCTGCCGCTGCGGTCCGTCGGTCGGTCAGTCAGTCCCTT
CGCGCTCCTGAGCCGCCGGCGCGCCGGGCGCCCCGGGAATTTATAAGTATTTGACCGTACTCAAAATGTGCAAGGAAGAATAATGGAAGC
CCCTGAATACCTTGATTTGGATGAAATTGACTTTAGTGATGACATATCTCTAGAGACCGTTGGATGGCAGCTTAACCTTCAGATGGCTCA
CTCTGCTCAAGCAAAACTAAAATCTCCTCAAGCTGTGTTACAACTCGGAGTGAACAATGAAGATTCAAAGAGCCTGGAGAAAGTTCTTGT
GGAATTCAGTCACAAGGAGTTGTTTGATTTCTATAACAAGCTAGAGACTATACAAGCACAGCTGGATTCCCTTACATGATGTTTTCGAAG
ACTGTTTTTTTCATCACGCTCCTGCCACCTCATTATTTTGCATTGAAGATACATTGCCAGGTTGTGTTTTCTGAAGGATTCAGTGACTTG
CTTTCTGTAAATTATATGGCTTATCACTTCTTAGACAAATAACAACCAATAGAGATCATTGTTAAGAATACTGAGGTTCTAATATACTTT
CTTTAGTTCTGTGAGCCAACAGTAATTATTAAGAACACTTTCCCTTTAAAGGAAACAAAAGTGAATACCATATTGTTTTTACTGTCATAG
TGTTGCTTTCTTGCCTGTCCTGCTTAGTTTTTACTTGCTGGATGATACCATAATGTATCAAGGAGCGTCCATGGATACAAGATAAGATGT
GTACCTTAGTAGAATACAGAGCTTTGGTAATTACATGAATAAAATTAAGAAAATAGCCATATACAATCAAATACACTATGGCATTTTTAT
TTGAATATGATGAGTATATTTTGCTTCGGAAATAATATAGGAAGGAAATGTAAAATAGTGAGTAGTATGGTATCAGTTAATTCCAGTCTG
AGCTTCTCTGTCAACTTCAGTTTCTCTCTCAGTTTAATGATTTAATAATAGTCCAGGTTTTTGTGTGTTTTTCTTTATACTGCAAATTAA
TAATGATTCACTTTATAGTTTGGGAGACAGAATCAGGTCTTGAATAAAATAATTGTAATGAGTGCTAAATGGGCACCATTATTCGAATCA

>84452_84452_3_SNCAIP-COMMD10_SNCAIP_chr5_121726886_ENST00000261368_COMMD10_chr5_115469765_ENST00000274458_length(amino acids)=105AA_BP=
MIPYYSLFYISFLYYFRSKIYSSYSNKNAIVYLIVYGYFLNFIHVITKALYSTKVHILSCIHGRSLIHYGIIQQVKTKQDRQESNTMTVK

--------------------------------------------------------------
>84452_84452_4_SNCAIP-COMMD10_SNCAIP_chr5_121726886_ENST00000261368_COMMD10_chr5_115469765_ENST00000515539_length(transcript)=697nt_BP=319nt
GCGGCCGCCCAGGCTGCCCCCGCCCGCGCGCGCCCGTTGGGGGGCCCGGGGAGCGGCGCCCGCGGCCGGGCCGCATTGTGACGTAGCGGG
GCCGCGGCAGCGCCTCCACCGCCCGCCTACTTCGGCTGAGGCTGTTCTGCTCCTGCCGCTGCGGTCCGTCGGTCGGTCAGTCAGTCCCTT
CGCGCTCCTGAGCCGCCGGCGCGCCGGGCGCCCCGGGAATTTATAAGTATTTGACCGTACTCAAAATGTGCAAGGAAGAATAATGGAAGC
CCCTGAATACCTTGATTTGGATGAAATTGACTTTAGTGATGACATATCTCTAGAGACCGTTGGATGGCAGCTTAACCTTCAGATGGCTCA
CTCTGCTCAAGCAAAACTAAAATCTCCTCAAGCTGTGTTACAACTCGGAGTGAACAATGAAGATTCAAAGAGCCTGGAGAAAGTTCTTGT
GGAATTCAGTCACAAGGAGTTGTTTGATTTCTATAACAAGCTAGAGACTATACAAGCACAGCTGGATTCCCTTACATGATGTTTTCGAAG
ACTGTTTTTTTCATCACGCTCCTGCCACCTCATTATTTTGCATTGAAGATACATTGCCAGGTTGTGTTTTCTGAAGGATTCAGTGACTTG

>84452_84452_4_SNCAIP-COMMD10_SNCAIP_chr5_121726886_ENST00000261368_COMMD10_chr5_115469765_ENST00000515539_length(amino acids)=88AA_BP=19

--------------------------------------------------------------
>84452_84452_5_SNCAIP-COMMD10_SNCAIP_chr5_121726886_ENST00000379533_COMMD10_chr5_115469765_ENST00000274458_length(transcript)=1271nt_BP=263nt
CGCCCGCGGCCGGGCCGCATTGTGACGTAGCGGGGCCGCGGCAGCGCCTCCACCGCCCGCCTACTTCGGCTGAGGCTGTTCTGCTCCTGC
CGCTGCGGTCCGTCGGTCGGTCAGTCAGTCCCTTCGCGCTCCTGAGCCGCCGGCGCGCCGGGCGCCCCGGGAATTTATAAGTATTTGACC
GTACTCAAAATGTGCAAGGAAGAATAATGGAAGCCCCTGAATACCTTGATTTGGATGAAATTGACTTTAGTGATGACATATCTCTAGAGA
CCGTTGGATGGCAGCTTAACCTTCAGATGGCTCACTCTGCTCAAGCAAAACTAAAATCTCCTCAAGCTGTGTTACAACTCGGAGTGAACA
ATGAAGATTCAAAGAGCCTGGAGAAAGTTCTTGTGGAATTCAGTCACAAGGAGTTGTTTGATTTCTATAACAAGCTAGAGACTATACAAG
CACAGCTGGATTCCCTTACATGATGTTTTCGAAGACTGTTTTTTTCATCACGCTCCTGCCACCTCATTATTTTGCATTGAAGATACATTG
CCAGGTTGTGTTTTCTGAAGGATTCAGTGACTTGCTTTCTGTAAATTATATGGCTTATCACTTCTTAGACAAATAACAACCAATAGAGAT
CATTGTTAAGAATACTGAGGTTCTAATATACTTTCTTTAGTTCTGTGAGCCAACAGTAATTATTAAGAACACTTTCCCTTTAAAGGAAAC
AAAAGTGAATACCATATTGTTTTTACTGTCATAGTGTTGCTTTCTTGCCTGTCCTGCTTAGTTTTTACTTGCTGGATGATACCATAATGT
ATCAAGGAGCGTCCATGGATACAAGATAAGATGTGTACCTTAGTAGAATACAGAGCTTTGGTAATTACATGAATAAAATTAAGAAAATAG
CCATATACAATCAAATACACTATGGCATTTTTATTTGAATATGATGAGTATATTTTGCTTCGGAAATAATATAGGAAGGAAATGTAAAAT
AGTGAGTAGTATGGTATCAGTTAATTCCAGTCTGAGCTTCTCTGTCAACTTCAGTTTCTCTCTCAGTTTAATGATTTAATAATAGTCCAG
GTTTTTGTGTGTTTTTCTTTATACTGCAAATTAATAATGATTCACTTTATAGTTTGGGAGACAGAATCAGGTCTTGAATAAAATAATTGT
AATGAGTGCTAAATGGGCACCATTATTCGAATCAGATACCTTTTATATTCTCTTTCCATAAATACGTTGATTTCTGTCAATAAAATTTTT

>84452_84452_5_SNCAIP-COMMD10_SNCAIP_chr5_121726886_ENST00000379533_COMMD10_chr5_115469765_ENST00000274458_length(amino acids)=105AA_BP=
MIPYYSLFYISFLYYFRSKIYSSYSNKNAIVYLIVYGYFLNFIHVITKALYSTKVHILSCIHGRSLIHYGIIQQVKTKQDRQESNTMTVK

--------------------------------------------------------------
>84452_84452_6_SNCAIP-COMMD10_SNCAIP_chr5_121726886_ENST00000379533_COMMD10_chr5_115469765_ENST00000515539_length(transcript)=641nt_BP=263nt
CGCCCGCGGCCGGGCCGCATTGTGACGTAGCGGGGCCGCGGCAGCGCCTCCACCGCCCGCCTACTTCGGCTGAGGCTGTTCTGCTCCTGC
CGCTGCGGTCCGTCGGTCGGTCAGTCAGTCCCTTCGCGCTCCTGAGCCGCCGGCGCGCCGGGCGCCCCGGGAATTTATAAGTATTTGACC
GTACTCAAAATGTGCAAGGAAGAATAATGGAAGCCCCTGAATACCTTGATTTGGATGAAATTGACTTTAGTGATGACATATCTCTAGAGA
CCGTTGGATGGCAGCTTAACCTTCAGATGGCTCACTCTGCTCAAGCAAAACTAAAATCTCCTCAAGCTGTGTTACAACTCGGAGTGAACA
ATGAAGATTCAAAGAGCCTGGAGAAAGTTCTTGTGGAATTCAGTCACAAGGAGTTGTTTGATTTCTATAACAAGCTAGAGACTATACAAG
CACAGCTGGATTCCCTTACATGATGTTTTCGAAGACTGTTTTTTTCATCACGCTCCTGCCACCTCATTATTTTGCATTGAAGATACATTG
CCAGGTTGTGTTTTCTGAAGGATTCAGTGACTTGCTTTCTGTAAATTATATGGCTTATCACTTCTTAGACAAATAACAACCAATAGAGAT

>84452_84452_6_SNCAIP-COMMD10_SNCAIP_chr5_121726886_ENST00000379533_COMMD10_chr5_115469765_ENST00000515539_length(amino acids)=88AA_BP=19

--------------------------------------------------------------
>84452_84452_7_SNCAIP-COMMD10_SNCAIP_chr5_121726886_ENST00000379536_COMMD10_chr5_115469765_ENST00000274458_length(transcript)=1271nt_BP=263nt
CGCCCGCGGCCGGGCCGCATTGTGACGTAGCGGGGCCGCGGCAGCGCCTCCACCGCCCGCCTACTTCGGCTGAGGCTGTTCTGCTCCTGC
CGCTGCGGTCCGTCGGTCGGTCAGTCAGTCCCTTCGCGCTCCTGAGCCGCCGGCGCGCCGGGCGCCCCGGGAATTTATAAGTATTTGACC
GTACTCAAAATGTGCAAGGAAGAATAATGGAAGCCCCTGAATACCTTGATTTGGATGAAATTGACTTTAGTGATGACATATCTCTAGAGA
CCGTTGGATGGCAGCTTAACCTTCAGATGGCTCACTCTGCTCAAGCAAAACTAAAATCTCCTCAAGCTGTGTTACAACTCGGAGTGAACA
ATGAAGATTCAAAGAGCCTGGAGAAAGTTCTTGTGGAATTCAGTCACAAGGAGTTGTTTGATTTCTATAACAAGCTAGAGACTATACAAG
CACAGCTGGATTCCCTTACATGATGTTTTCGAAGACTGTTTTTTTCATCACGCTCCTGCCACCTCATTATTTTGCATTGAAGATACATTG
CCAGGTTGTGTTTTCTGAAGGATTCAGTGACTTGCTTTCTGTAAATTATATGGCTTATCACTTCTTAGACAAATAACAACCAATAGAGAT
CATTGTTAAGAATACTGAGGTTCTAATATACTTTCTTTAGTTCTGTGAGCCAACAGTAATTATTAAGAACACTTTCCCTTTAAAGGAAAC
AAAAGTGAATACCATATTGTTTTTACTGTCATAGTGTTGCTTTCTTGCCTGTCCTGCTTAGTTTTTACTTGCTGGATGATACCATAATGT
ATCAAGGAGCGTCCATGGATACAAGATAAGATGTGTACCTTAGTAGAATACAGAGCTTTGGTAATTACATGAATAAAATTAAGAAAATAG
CCATATACAATCAAATACACTATGGCATTTTTATTTGAATATGATGAGTATATTTTGCTTCGGAAATAATATAGGAAGGAAATGTAAAAT
AGTGAGTAGTATGGTATCAGTTAATTCCAGTCTGAGCTTCTCTGTCAACTTCAGTTTCTCTCTCAGTTTAATGATTTAATAATAGTCCAG
GTTTTTGTGTGTTTTTCTTTATACTGCAAATTAATAATGATTCACTTTATAGTTTGGGAGACAGAATCAGGTCTTGAATAAAATAATTGT
AATGAGTGCTAAATGGGCACCATTATTCGAATCAGATACCTTTTATATTCTCTTTCCATAAATACGTTGATTTCTGTCAATAAAATTTTT

>84452_84452_7_SNCAIP-COMMD10_SNCAIP_chr5_121726886_ENST00000379536_COMMD10_chr5_115469765_ENST00000274458_length(amino acids)=105AA_BP=
MIPYYSLFYISFLYYFRSKIYSSYSNKNAIVYLIVYGYFLNFIHVITKALYSTKVHILSCIHGRSLIHYGIIQQVKTKQDRQESNTMTVK

--------------------------------------------------------------
>84452_84452_8_SNCAIP-COMMD10_SNCAIP_chr5_121726886_ENST00000379536_COMMD10_chr5_115469765_ENST00000515539_length(transcript)=641nt_BP=263nt
CGCCCGCGGCCGGGCCGCATTGTGACGTAGCGGGGCCGCGGCAGCGCCTCCACCGCCCGCCTACTTCGGCTGAGGCTGTTCTGCTCCTGC
CGCTGCGGTCCGTCGGTCGGTCAGTCAGTCCCTTCGCGCTCCTGAGCCGCCGGCGCGCCGGGCGCCCCGGGAATTTATAAGTATTTGACC
GTACTCAAAATGTGCAAGGAAGAATAATGGAAGCCCCTGAATACCTTGATTTGGATGAAATTGACTTTAGTGATGACATATCTCTAGAGA
CCGTTGGATGGCAGCTTAACCTTCAGATGGCTCACTCTGCTCAAGCAAAACTAAAATCTCCTCAAGCTGTGTTACAACTCGGAGTGAACA
ATGAAGATTCAAAGAGCCTGGAGAAAGTTCTTGTGGAATTCAGTCACAAGGAGTTGTTTGATTTCTATAACAAGCTAGAGACTATACAAG
CACAGCTGGATTCCCTTACATGATGTTTTCGAAGACTGTTTTTTTCATCACGCTCCTGCCACCTCATTATTTTGCATTGAAGATACATTG
CCAGGTTGTGTTTTCTGAAGGATTCAGTGACTTGCTTTCTGTAAATTATATGGCTTATCACTTCTTAGACAAATAACAACCAATAGAGAT

>84452_84452_8_SNCAIP-COMMD10_SNCAIP_chr5_121726886_ENST00000379536_COMMD10_chr5_115469765_ENST00000515539_length(amino acids)=88AA_BP=19

--------------------------------------------------------------
>84452_84452_9_SNCAIP-COMMD10_SNCAIP_chr5_121726886_ENST00000503116_COMMD10_chr5_115469765_ENST00000274458_length(transcript)=1065nt_BP=57nt
ATGGAAGCCCCTGAATACCTTGATTTGGATGAAATTGACTTTAGTGATGACATATCTCTAGAGACCGTTGGATGGCAGCTTAACCTTCAG
ATGGCTCACTCTGCTCAAGCAAAACTAAAATCTCCTCAAGCTGTGTTACAACTCGGAGTGAACAATGAAGATTCAAAGAGCCTGGAGAAA
GTTCTTGTGGAATTCAGTCACAAGGAGTTGTTTGATTTCTATAACAAGCTAGAGACTATACAAGCACAGCTGGATTCCCTTACATGATGT
TTTCGAAGACTGTTTTTTTCATCACGCTCCTGCCACCTCATTATTTTGCATTGAAGATACATTGCCAGGTTGTGTTTTCTGAAGGATTCA
GTGACTTGCTTTCTGTAAATTATATGGCTTATCACTTCTTAGACAAATAACAACCAATAGAGATCATTGTTAAGAATACTGAGGTTCTAA
TATACTTTCTTTAGTTCTGTGAGCCAACAGTAATTATTAAGAACACTTTCCCTTTAAAGGAAACAAAAGTGAATACCATATTGTTTTTAC
TGTCATAGTGTTGCTTTCTTGCCTGTCCTGCTTAGTTTTTACTTGCTGGATGATACCATAATGTATCAAGGAGCGTCCATGGATACAAGA
TAAGATGTGTACCTTAGTAGAATACAGAGCTTTGGTAATTACATGAATAAAATTAAGAAAATAGCCATATACAATCAAATACACTATGGC
ATTTTTATTTGAATATGATGAGTATATTTTGCTTCGGAAATAATATAGGAAGGAAATGTAAAATAGTGAGTAGTATGGTATCAGTTAATT
CCAGTCTGAGCTTCTCTGTCAACTTCAGTTTCTCTCTCAGTTTAATGATTTAATAATAGTCCAGGTTTTTGTGTGTTTTTCTTTATACTG
CAAATTAATAATGATTCACTTTATAGTTTGGGAGACAGAATCAGGTCTTGAATAAAATAATTGTAATGAGTGCTAAATGGGCACCATTAT

>84452_84452_9_SNCAIP-COMMD10_SNCAIP_chr5_121726886_ENST00000503116_COMMD10_chr5_115469765_ENST00000274458_length(amino acids)=105AA_BP=
MIPYYSLFYISFLYYFRSKIYSSYSNKNAIVYLIVYGYFLNFIHVITKALYSTKVHILSCIHGRSLIHYGIIQQVKTKQDRQESNTMTVK

--------------------------------------------------------------
>84452_84452_10_SNCAIP-COMMD10_SNCAIP_chr5_121726886_ENST00000503116_COMMD10_chr5_115469765_ENST00000515539_length(transcript)=435nt_BP=57nt
ATGGAAGCCCCTGAATACCTTGATTTGGATGAAATTGACTTTAGTGATGACATATCTCTAGAGACCGTTGGATGGCAGCTTAACCTTCAG
ATGGCTCACTCTGCTCAAGCAAAACTAAAATCTCCTCAAGCTGTGTTACAACTCGGAGTGAACAATGAAGATTCAAAGAGCCTGGAGAAA
GTTCTTGTGGAATTCAGTCACAAGGAGTTGTTTGATTTCTATAACAAGCTAGAGACTATACAAGCACAGCTGGATTCCCTTACATGATGT
TTTCGAAGACTGTTTTTTTCATCACGCTCCTGCCACCTCATTATTTTGCATTGAAGATACATTGCCAGGTTGTGTTTTCTGAAGGATTCA

>84452_84452_10_SNCAIP-COMMD10_SNCAIP_chr5_121726886_ENST00000503116_COMMD10_chr5_115469765_ENST00000515539_length(amino acids)=88AA_BP=19

--------------------------------------------------------------
>84452_84452_11_SNCAIP-COMMD10_SNCAIP_chr5_121726886_ENST00000504884_COMMD10_chr5_115469765_ENST00000274458_length(transcript)=1065nt_BP=57nt
ATGGAAGCCCCTGAATACCTTGATTTGGATGAAATTGACTTTAGTGATGACATATCTCTAGAGACCGTTGGATGGCAGCTTAACCTTCAG
ATGGCTCACTCTGCTCAAGCAAAACTAAAATCTCCTCAAGCTGTGTTACAACTCGGAGTGAACAATGAAGATTCAAAGAGCCTGGAGAAA
GTTCTTGTGGAATTCAGTCACAAGGAGTTGTTTGATTTCTATAACAAGCTAGAGACTATACAAGCACAGCTGGATTCCCTTACATGATGT
TTTCGAAGACTGTTTTTTTCATCACGCTCCTGCCACCTCATTATTTTGCATTGAAGATACATTGCCAGGTTGTGTTTTCTGAAGGATTCA
GTGACTTGCTTTCTGTAAATTATATGGCTTATCACTTCTTAGACAAATAACAACCAATAGAGATCATTGTTAAGAATACTGAGGTTCTAA
TATACTTTCTTTAGTTCTGTGAGCCAACAGTAATTATTAAGAACACTTTCCCTTTAAAGGAAACAAAAGTGAATACCATATTGTTTTTAC
TGTCATAGTGTTGCTTTCTTGCCTGTCCTGCTTAGTTTTTACTTGCTGGATGATACCATAATGTATCAAGGAGCGTCCATGGATACAAGA
TAAGATGTGTACCTTAGTAGAATACAGAGCTTTGGTAATTACATGAATAAAATTAAGAAAATAGCCATATACAATCAAATACACTATGGC
ATTTTTATTTGAATATGATGAGTATATTTTGCTTCGGAAATAATATAGGAAGGAAATGTAAAATAGTGAGTAGTATGGTATCAGTTAATT
CCAGTCTGAGCTTCTCTGTCAACTTCAGTTTCTCTCTCAGTTTAATGATTTAATAATAGTCCAGGTTTTTGTGTGTTTTTCTTTATACTG
CAAATTAATAATGATTCACTTTATAGTTTGGGAGACAGAATCAGGTCTTGAATAAAATAATTGTAATGAGTGCTAAATGGGCACCATTAT

>84452_84452_11_SNCAIP-COMMD10_SNCAIP_chr5_121726886_ENST00000504884_COMMD10_chr5_115469765_ENST00000274458_length(amino acids)=105AA_BP=
MIPYYSLFYISFLYYFRSKIYSSYSNKNAIVYLIVYGYFLNFIHVITKALYSTKVHILSCIHGRSLIHYGIIQQVKTKQDRQESNTMTVK

--------------------------------------------------------------
>84452_84452_12_SNCAIP-COMMD10_SNCAIP_chr5_121726886_ENST00000504884_COMMD10_chr5_115469765_ENST00000515539_length(transcript)=435nt_BP=57nt
ATGGAAGCCCCTGAATACCTTGATTTGGATGAAATTGACTTTAGTGATGACATATCTCTAGAGACCGTTGGATGGCAGCTTAACCTTCAG
ATGGCTCACTCTGCTCAAGCAAAACTAAAATCTCCTCAAGCTGTGTTACAACTCGGAGTGAACAATGAAGATTCAAAGAGCCTGGAGAAA
GTTCTTGTGGAATTCAGTCACAAGGAGTTGTTTGATTTCTATAACAAGCTAGAGACTATACAAGCACAGCTGGATTCCCTTACATGATGT
TTTCGAAGACTGTTTTTTTCATCACGCTCCTGCCACCTCATTATTTTGCATTGAAGATACATTGCCAGGTTGTGTTTTCTGAAGGATTCA

>84452_84452_12_SNCAIP-COMMD10_SNCAIP_chr5_121726886_ENST00000504884_COMMD10_chr5_115469765_ENST00000515539_length(amino acids)=88AA_BP=19

--------------------------------------------------------------

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Fusion Gene PPI Analysis for SNCAIP-COMMD10


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for SNCAIP-COMMD10


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for SNCAIP-COMMD10


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource