Home

Download

Statistics

Examples

Help

Contact

	Fusion Gene Summary
	Fusion Gene ORF analysis
	Fusion Genomic Features
	Fusion Protein Features
	Fusion Gene Sequence
	Fusion Gene PPI analysis
	Related Drugs
	Related Diseases

Fusion gene:SNX18-ANKRD55 (FusionGDB2 ID:84898)

Fusion Gene Summary for SNX18-ANKRD55

Fusion gene summary

Fusion gene information	Fusion gene name: SNX18-ANKRD55
	Fusion gene ID: 84898
		Hgene	Tgene
	Gene symbol	SNX18	ANKRD55
	Gene ID	112574	79722
	Gene name	sorting nexin 18	ankyrin repeat domain 55
	Synonyms	SH3PX2\|SH3PXD3B\|SNAG1	-
	Cytomap	5q11.2	5q11.2
	Type of gene	protein-coding	protein-coding
	Description	sorting nexin-18SH3 and PX domain-containing protein 3Bsorting nexin associated golgi protein 1sorting nexin-associated Golgi protein 1	ankyrin repeat domain-containing protein 55
	Modification date	20200313	20200313
	UniProtAcc	.	.
	Ensembl transtripts involved in fusion gene	ENST00000326277, ENST00000343017, ENST00000381410,	ENST00000513241, ENST00000434982, ENST00000505970, ENST00000341048, ENST00000504958,
Fusion gene scores	* DoF score	4 X 6 X 4=96	9 X 7 X 6=378
	# samples	5	10
	** MAII score	log2(5/96*10)=-0.941106310946431 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0	log2(10/378*10)=-1.91838623444635 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0
Context	PubMed: SNX18 [Title/Abstract] AND ANKRD55 [Title/Abstract] AND fusion [Title/Abstract]
Most frequent breakpoint	SNX18(53815403)-ANKRD55(55479461), # samples:1
Anticipated loss of major functional domain due to fusion event.

* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Partner	Gene	GO ID	GO term	PubMed ID
Hgene	SNX18	GO:0006897	endocytosis	20427313
Hgene	SNX18	GO:0043547	positive regulation of GTPase activity	20427313

Fusion gene breakpoints across SNX18 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion gene breakpoints across ANKRD55 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

Source	Disease	Sample	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
ChimerDB4	LUAD	TCGA-MP-A4T8-01A	SNX18	chr5	53815403	-	ANKRD55	chr5	55479461	-

Top

Fusion Gene ORF analysis for SNX18-ANKRD55

Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

ORF	Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
5CDS-5UTR	ENST00000326277	ENST00000513241	SNX18	chr5	53815403	-	ANKRD55	chr5	55479461	-
5CDS-5UTR	ENST00000343017	ENST00000513241	SNX18	chr5	53815403	-	ANKRD55	chr5	55479461	-
5CDS-5UTR	ENST00000381410	ENST00000513241	SNX18	chr5	53815403	-	ANKRD55	chr5	55479461	-
5CDS-intron	ENST00000326277	ENST00000434982	SNX18	chr5	53815403	-	ANKRD55	chr5	55479461	-
5CDS-intron	ENST00000326277	ENST00000505970	SNX18	chr5	53815403	-	ANKRD55	chr5	55479461	-
5CDS-intron	ENST00000343017	ENST00000434982	SNX18	chr5	53815403	-	ANKRD55	chr5	55479461	-
5CDS-intron	ENST00000343017	ENST00000505970	SNX18	chr5	53815403	-	ANKRD55	chr5	55479461	-
5CDS-intron	ENST00000381410	ENST00000434982	SNX18	chr5	53815403	-	ANKRD55	chr5	55479461	-
5CDS-intron	ENST00000381410	ENST00000505970	SNX18	chr5	53815403	-	ANKRD55	chr5	55479461	-
Frame-shift	ENST00000326277	ENST00000341048	SNX18	chr5	53815403	-	ANKRD55	chr5	55479461	-
Frame-shift	ENST00000326277	ENST00000504958	SNX18	chr5	53815403	-	ANKRD55	chr5	55479461	-
In-frame	ENST00000343017	ENST00000341048	SNX18	chr5	53815403	-	ANKRD55	chr5	55479461	-
In-frame	ENST00000343017	ENST00000504958	SNX18	chr5	53815403	-	ANKRD55	chr5	55479461	-
In-frame	ENST00000381410	ENST00000341048	SNX18	chr5	53815403	-	ANKRD55	chr5	55479461	-
In-frame	ENST00000381410	ENST00000504958	SNX18	chr5	53815403	-	ANKRD55	chr5	55479461	-

ORFfinder result based on the fusion transcript sequence of in-frame fusion genes.

Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	Seq length (transcript)	BP loci (transcript)	Predicted start (transcript)	Predicted stop (transcript)	Seq length (amino acids)
ENST00000343017	SNX18	chr5	53815403	-	ENST00000341048	ANKRD55	chr5	55479461	-	2443	153	38	1939	633
ENST00000343017	SNX18	chr5	53815403	-	ENST00000504958	ANKRD55	chr5	55479461	-	2221	153	38	1810	590
ENST00000381410	SNX18	chr5	53815403	-	ENST00000341048	ANKRD55	chr5	55479461	-	4101	1811	4	3597	1197
ENST00000381410	SNX18	chr5	53815403	-	ENST00000504958	ANKRD55	chr5	55479461	-	3879	1811	4	3468	1154

DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.

Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	No-coding score	Coding score
ENST00000343017	ENST00000341048	SNX18	chr5	53815403	-	ANKRD55	chr5	55479461	-	0.007108972	0.9928911
ENST00000343017	ENST00000504958	SNX18	chr5	53815403	-	ANKRD55	chr5	55479461	-	0.005580566	0.9944194
ENST00000381410	ENST00000341048	SNX18	chr5	53815403	-	ANKRD55	chr5	55479461	-	0.003969008	0.996031
ENST00000381410	ENST00000504958	SNX18	chr5	53815403	-	ANKRD55	chr5	55479461	-	0.003137151	0.9968629

Top

Fusion Genomic Features for SNX18-ANKRD55

FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.

Hgene

Hchr

Hbp

Hstrand

Tgene

Tchr

Tbp

Tstrand

1-p

p (fusion gene breakpoint)

Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.

Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

Top

Fusion Protein Features for SNX18-ANKRD55

Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr5:53815403/chr5:55479461)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.

Main function of each fusion partner protein. (from UniProt)

Hgene	Tgene
.	.
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.	FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at
download page

* Minus value of BPloci means that the break pointn is located before the CDS.

- In-frame and retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

Hgene

SNX18

chr5:53815403

chr5:55479461

ENST00000381410

1_61

540

625.0

Domain

SH3

Hgene

SNX18

chr5:53815403

chr5:55479461

ENST00000381410

276_386

540

625.0

Domain

Tgene

ANKRD55

chr5:53815403

chr5:55479461

ENST00000341048

126_157

615.0

Repeat

Note=ANK 4

Tgene

ANKRD55

chr5:53815403

chr5:55479461

ENST00000341048

161_190

615.0

Repeat

Note=ANK 5

Tgene

ANKRD55

chr5:53815403

chr5:55479461

ENST00000341048

194_223

615.0

Repeat

Note=ANK 6

Tgene

ANKRD55

chr5:53815403

chr5:55479461

ENST00000341048

230_260

615.0

Repeat

Note=ANK 7

Tgene

ANKRD55

chr5:53815403

chr5:55479461

ENST00000341048

264_293

615.0

Repeat

Note=ANK 8

Tgene

ANKRD55

chr5:53815403

chr5:55479461

ENST00000341048

26_55

615.0

Repeat

Note=ANK 1

Tgene

ANKRD55

chr5:53815403

chr5:55479461

ENST00000341048

297_326

615.0

Repeat

Note=ANK 9

Tgene

ANKRD55

chr5:53815403

chr5:55479461

ENST00000341048

60_89

615.0

Repeat

Note=ANK 2

Tgene

ANKRD55

chr5:53815403

chr5:55479461

ENST00000341048

93_125

615.0

Repeat

Note=ANK 3

Tgene

ANKRD55

chr5:53815403

chr5:55479461

ENST00000434982

126_157

327.0

Repeat

Note=ANK 4

Tgene

ANKRD55

chr5:53815403

chr5:55479461

ENST00000434982

161_190

327.0

Repeat

Note=ANK 5

Tgene

ANKRD55

chr5:53815403

chr5:55479461

ENST00000434982

194_223

327.0

Repeat

Note=ANK 6

Tgene

ANKRD55

chr5:53815403

chr5:55479461

ENST00000434982

230_260

327.0

Repeat

Note=ANK 7

Tgene

ANKRD55

chr5:53815403

chr5:55479461

ENST00000434982

264_293

327.0

Repeat

Note=ANK 8

Tgene

ANKRD55

chr5:53815403

chr5:55479461

ENST00000434982

26_55

327.0

Repeat

Note=ANK 1

Tgene

ANKRD55

chr5:53815403

chr5:55479461

ENST00000434982

297_326

327.0

Repeat

Note=ANK 9

Tgene

ANKRD55

chr5:53815403

chr5:55479461

ENST00000434982

60_89

327.0

Repeat

Note=ANK 2

Tgene

ANKRD55

chr5:53815403

chr5:55479461

ENST00000434982

93_125

327.0

Repeat

Note=ANK 3

- In-frame and not-retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

Hgene

SNX18

chr5:53815403

chr5:55479461

ENST00000326277

1_61

629.0

Domain

SH3

Hgene

SNX18

chr5:53815403

chr5:55479461

ENST00000326277

276_386

629.0

Domain

Hgene

SNX18

chr5:53815403

chr5:55479461

ENST00000326277

421_628

629.0

Domain

Note=BAR

Hgene

SNX18

chr5:53815403

chr5:55479461

ENST00000343017

1_61

592.0

Domain

SH3

Hgene

SNX18

chr5:53815403

chr5:55479461

ENST00000343017

276_386

592.0

Domain

Hgene

SNX18

chr5:53815403

chr5:55479461

ENST00000343017

421_628

592.0

Domain

Note=BAR

Hgene

SNX18

chr5:53815403

chr5:55479461

ENST00000381410

421_628

540

625.0

Domain

Note=BAR

Top

Fusion Gene Sequence for SNX18-ANKRD55

For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.

>84898_84898_1_SNX18-ANKRD55_SNX18_chr5_53815403_ENST00000343017_ANKRD55_chr5_55479461_ENST00000341048_length(transcript)=2443nt_BP=153nt
GTAAAGCCTGGCCCTTAGAGCAGGTGATATGGAGTGTATTGTGCAGGCTGAAAGGGGCGACTTTGACAGCAGTACCACTGTGGGTTTCAG
AATCATATTCTACAGGTGAGGAAGCGAGCAGAGACGTGGACGCCTGGGTCTTTTCCCTAGAGTGTGACTCATCTGAGGAAGTTGACCTGA
CCATGGTTTATCAAGCAGCCTCTAATGGAGATGTCAATGCTCTGACTGCAGTGATTCGGGAAGACCCTTCTATCCTAGAATGCTGTGACA
GTGAAGGATGCACGCCCTTGATGCATGCGGTTTCTGGACGTCAAGCGGACACAGTGAAGCTGCTGTTGAAGATGGGAGCCAATATTAACA
TGCAGGATGCTTATGGCCGCACAAGTTTATGCCTGGCCACCTACCTGGGCTGGCTTGAAGGCTGTGTGAGTCTACTCAGAAACGGTGCCA
AGCACAATATCCCAGATAAAAATGGCCGCCTGCCACTGCATGCTGCCACTGCTGAGCCCGATATGAGGCTCCTCACGGTCCTGTTGCAAC
AGTCGAACATCAGCGAGATTAATCACCAGGACAATGAGGGAATGACACCACTCCACTGGGCGGCTTTCCACAACCAGCCTCAACACACAC
AAATGCTGCTGAAGAAGGGGGCAGACCCCACCCTTGTGGATAAAGACTTTAAAACCGCTCTCCACTGGGCAGTCCAGAGTGGAAATAGGA
TTCTGTGCTCCATCATTCTGAGCCATCACCAGGGGCCGTCCATAATCAACTATGATGATGAGAGTGGGAAGACATGTGTACATATCGCAG
CGGCAGCGGGCTTCAGCGATATTATTCATGAGCTGGCAAGAGTCCCTGAGTGTAACCTGCAGGCTCTGGATGTGGATGACAGGACACCTC
TGCACTGGGCTGCAGCTGCAGGGAAGGCCGAATGTGTCCAGTCACTGCTGGAGTTGGGAATGGACAGCAACCTGCGGGACATCAATGAGA
GCACGCCCTTGGCCTATGCCCTGTACTGCGGTCACACGGCGTGTGTCAAACTCCTCTCCCAAGAGAGCAGAACAGAGCCTACTCGACCCC
CTCCCTCCCAGAGCAGTCGGCCCCAGAAGAAGGAGAGACGGTTCAACGTGCTCAACCAAATATTCTGCAAAAACAAGAAAGAAGAGCAGA
GAGCCCATCAGAAGGATCCCAGCAGGGACCGATACAGAGAGGAGGACACCTCAGAAGTCAATGACATCATCACCACCTTTGATAGCATCG
TGGGTACCAACTGCCAAGAACAGCCTGGTGATCAGGTGGCTATGGTTGAATTTAAGAAGAAAACCTCAGACAATTCAAAATATCTCTTAC
CAGAAAAGAAACCGCTGGCCCGTAAGGGGCTTCCACCAATCAGAACGCAGAGTCTCCCACCCATCACCCTGGGCAATAACTTCCTAACAG
CCTCCCATAGGGCCACTTCCCATGCAGGCCTGAGCTCTGCTCCTCATCATATGGCCCAGCGATCTCAGAAAAGTCGAAGTGAGCAGGATT
TATTAAATAACAGAACTGGCTGCCAGATGTTACTAGATAACCCCTGGAAGAGTGATTCTAATCAGGTATTTTCCTACAAAGTTTGGACTG
TGTCTTCTTCTGATAAGCTGCTGGACAGATTGCTCAGTGTCCGGCCTGGTCACCAAGAGGTCTCCGTGCCACCACACCTTCGCCATCTAC
ATAATCCATCATCAGGACAAAATTTTCAGCATCTTTCCCCAAACAGACACAAAATCAGGGATCTTCCTTTCACTCGGAACAACCTAGCTC
CCCTACCAGATCAAAAATTTCTATCTGGAGAACCTCTGCGGACAAACCGAGTGCTTCCTGCAATTCCAAGTCAACGAAGACACAGCACAG
CAGCAGAAGAGAGTGAACATTCTGCCAACCCCACCAGTGATGAAAATTAACTGTGGGCCACTCGCTGCAGAAATGTAGATGAATATGTAT
TTTCAACTCTCAAAGGACAAGATTACTCCAGTTTGTAAGAACGAAGACCAATTTAGTAAGCTGCATTCTATAAGCCATCAGTTTTATAAC
TCGAAATTCTTTATTCCAAATAAAGATACTCCCTAAATAAGCACTTAGAATATTTGGGTGTGCATATTAAGTCTGTGAATTTCTGTGACT
TCCACATGCCAAAATTAAAAGACAAAATATGTTATCAGTAGGAAAACTGAGCTATGTTTGGTTTGCTTTGTGGCATGTGCACTGTTTTTT
TGTTATTGTTCTTTGGTTGTTTTTTTGCTGAATGATTTTATGTTTTGGGAAAAAAAGTACGCTTTGCTGAATAAAAGCAAAAAACAAAAC
AAAAAAAAAACCACATCCCAGACAAACATGTCTTCACATTTATTGTCATTCTAACTTGAACTAATGAAACCTATTTAAAAATAAATTCCT

>84898_84898_1_SNX18-ANKRD55_SNX18_chr5_53815403_ENST00000343017_ANKRD55_chr5_55479461_ENST00000341048_length(amino acids)=633AA_BP=37
MCRLKGATLTAVPLWVSESYSTGEEASRDVDAWVFSLECDSSEEVDLTMVYQAASNGDVNALTAVIREDPSILECCDSEGCTPLMHAVSG
RQADTVKLLLKMGANINMQDAYGRTSLCLATYLGWLEGCVSLLRNGAKHNIPDKNGRLPLHAATAEPDMRLLTVLLQQSNISEINHQDNE
GMTPLHWAAFHNQPQHTQMLLKKGADPTLVDKDFKTALHWAVQSGNRILCSIILSHHQGPSIINYDDESGKTCVHIAAAAGFSDIIHELA
RVPECNLQALDVDDRTPLHWAAAAGKAECVQSLLELGMDSNLRDINESTPLAYALYCGHTACVKLLSQESRTEPTRPPPSQSSRPQKKER
RFNVLNQIFCKNKKEEQRAHQKDPSRDRYREEDTSEVNDIITTFDSIVGTNCQEQPGDQVAMVEFKKKTSDNSKYLLPEKKPLARKGLPP
IRTQSLPPITLGNNFLTASHRATSHAGLSSAPHHMAQRSQKSRSEQDLLNNRTGCQMLLDNPWKSDSNQVFSYKVWTVSSSDKLLDRLLS
VRPGHQEVSVPPHLRHLHNPSSGQNFQHLSPNRHKIRDLPFTRNNLAPLPDQKFLSGEPLRTNRVLPAIPSQRRHSTAAEESEHSANPTS

--------------------------------------------------------------
>84898_84898_2_SNX18-ANKRD55_SNX18_chr5_53815403_ENST00000343017_ANKRD55_chr5_55479461_ENST00000504958_length(transcript)=2221nt_BP=153nt
GTAAAGCCTGGCCCTTAGAGCAGGTGATATGGAGTGTATTGTGCAGGCTGAAAGGGGCGACTTTGACAGCAGTACCACTGTGGGTTTCAG
AATCATATTCTACAGGTGAGGAAGCGAGCAGAGACGTGGACGCCTGGGTCTTTTCCCTAGAGTGTGACTCATCTGAGGAAGTTGACCTGA
CCATGGTTTATCAAGCAGCCTCTAATGGAGATGTCAATGCTCTGACTGCAGTGATTCGGGAAGACCCTTCTATCCTAGAATGCTGTGACA
GTGAAGGATGCACGCCCTTGATGCATGCGGTTTCTGGACGTCAAGCGGACACAGTGAAGCTGCTGTTGAAGATGGGAGCCAATATTAACA
TGCAGGATGCTTATGGCCGCACAAGTTTATGCCTGGCCACCTACCTGGGCTGGCTTGAAGGCTGTGTGAGTCTACTCAGAAACGGTGCCA
AGCACAATATCCCAGATAAAAATGGCCGCCTGCCACTGCATGCTGCCACTGCTGAGCCCGATATGAGGCTCCTCACGGTCCTGTTGCAAC
AGTCGAACATCAGCGAGATTAATCACCAGGACAATGAGAGTGGAAATAGGATTCTGTGCTCCATCATTCTGAGCCATCACCAGGGGCCGT
CCATAATCAACTATGATGATGAGAGTGGGAAGACATGTGTACATATCGCAGCGGCAGCGGGCTTCAGCGATATTATTCATGAGCTGGCAA
GAGTCCCTGAGTGTAACCTGCAGGCTCTGGATGTGGATGACAGGACACCTCTGCACTGGGCTGCAGCTGCAGGGAAGGCCGAATGTGTCC
AGTCACTGCTGGAGTTGGGAATGGACAGCAACCTGCGGGACATCAATGAGAGCACGCCCTTGGCCTATGCCCTGTACTGCGGTCACACGG
CGTGTGTCAAACTCCTCTCCCAAGAGAGCAGAACAGAGCCTACTCGACCCCCTCCCTCCCAGAGCAGTCGGCCCCAGAAGAAGGAGAGAC
GGTTCAACGTGCTCAACCAAATATTCTGCAAAAACAAGAAAGAAGAGCAGAGAGCCCATCAGAAGGATCCCAGCAGGGACCGATACAGAG
AGGAGGACACCTCAGAAGTCAATGACATCATCACCACCTTTGATAGCATCGTGGGTACCAACTGCCAAGAACAGCCTGGTGATCAGGTGG
CTATGGTTGAATTTAAGAAGAAAACCTCAGACAATTCAAAATATCTCTTACCAGAAAAGAAACCGCTGGCCCGTAAGGGGCTTCCACCAA
TCAGAACGCAGAGTCTCCCACCCATCACCCTGGGCAATAACTTCCTAACAGCCTCCCATAGGGCCACTTCCCATGCAGGCCTGAGCTCTG
CTCCTCATCATATGGCCCAGCGATCTCAGAAAAGTCGAAGTGAGCAGGATTTATTAAATAACAGAACTGGCTGCCAGATGTTACTAGATA
ACCCCTGGAAGAGTGATTCTAATCAGGTATTTTCCTACAAAGTTTGGACTGTGTCTTCTTCTGATAAGCTGCTGGACAGATTGCTCAGTG
TCCGGCCTGGTCACCAAGAGGTCTCCGTGCCACCACACCTTCGCCATCTACATAATCCATCATCAGGACAAAATTTTCAGCATCTTTCCC
CAAACAGACACAAAATCAGGGATCTTCCTTTCACTCGGAACAACCTAGCTCCCCTACCAGATCAAAAATTTCTATCTGGAGAACCTCTGC
GGACAAACCGAGTGCTTCCTGCAATTCCAAGTCAACGAAGACACAGCACAGCAGCAGAAGAGAGTGAACATTCTGCCAACCCCACCAGTG
ATGAAAATTAACTGTGGGCCACTCGCTGCAGAAATGTAGATGAATATGTATTTTCAACTCTCAAAGGACAAGATTACTCCAGTTTGTAAG
AACGAAGACCAATTTAGTAAGCTGCATTCTATAAGCCATCAGTTTTATAACTCGAAATTCTTTATTCCAAATAAAGATACTCCCTAAATA
AGCACTTAGAATATTTGGGTGTGCATATTAAGTCTGTGAATTTCTGTGACTTCCACATGCCAAAATTAAAAGACAAAATATGTTATCAGT
AGGAAAACTGAGCTATGTTTGGTTTGCTTTGTGGCATGTGCACTGTTTTTTTGTTATTGTTCTTTGGTTGTTTTTTTGCTGAATGATTTT

>84898_84898_2_SNX18-ANKRD55_SNX18_chr5_53815403_ENST00000343017_ANKRD55_chr5_55479461_ENST00000504958_length(amino acids)=590AA_BP=37
MCRLKGATLTAVPLWVSESYSTGEEASRDVDAWVFSLECDSSEEVDLTMVYQAASNGDVNALTAVIREDPSILECCDSEGCTPLMHAVSG
RQADTVKLLLKMGANINMQDAYGRTSLCLATYLGWLEGCVSLLRNGAKHNIPDKNGRLPLHAATAEPDMRLLTVLLQQSNISEINHQDNE
SGNRILCSIILSHHQGPSIINYDDESGKTCVHIAAAAGFSDIIHELARVPECNLQALDVDDRTPLHWAAAAGKAECVQSLLELGMDSNLR
DINESTPLAYALYCGHTACVKLLSQESRTEPTRPPPSQSSRPQKKERRFNVLNQIFCKNKKEEQRAHQKDPSRDRYREEDTSEVNDIITT
FDSIVGTNCQEQPGDQVAMVEFKKKTSDNSKYLLPEKKPLARKGLPPIRTQSLPPITLGNNFLTASHRATSHAGLSSAPHHMAQRSQKSR
SEQDLLNNRTGCQMLLDNPWKSDSNQVFSYKVWTVSSSDKLLDRLLSVRPGHQEVSVPPHLRHLHNPSSGQNFQHLSPNRHKIRDLPFTR

--------------------------------------------------------------
>84898_84898_3_SNX18-ANKRD55_SNX18_chr5_53815403_ENST00000381410_ANKRD55_chr5_55479461_ENST00000341048_length(transcript)=4101nt_BP=1811nt
GGCGCTGCGAAGTGGAGGCGCTGCGAGCGGAGCCGCGCGGAGGGCGCGACCGGCTGGTCCGGGCAGCGTGGGTTTGCCGCCTTCGGGGCT
CCAGTCCGCGCGCCAGGGCTCGAGCAGTACCGCGGGCCCCTCAGGTGGGCCTCGGCTCGGGACGCCGGGAGTCGGGACCGCCAGTCGGGG
CGCCGGGACCATGGCGCTGCGCGCCCGGGCGCTGTACGACTTCAGGTCGGAGAACCCAGGAGAGATCTCGCTGCGAGAGCACGAGGTGCT
GAGCCTGTGCAGCGAGCAGGACATCGAGGGCTGGCTCGAGGGGGTCAACAGCCGCGGCGACCGCGGCCTCTTCCCGGCCTCCTATGTGCA
GGTGATCCGCGCCCCCGAGCCTGGCCCGGCGGGAGACGGCGGCCCGGGCGCCCCGGCCCGCTACGCCAATGTGCCCCCCGGGGGCTTCGA
GCCCCTGCCTGTCGCGCCCCCCGCCTCCTTCAAGCCGCCGCCTGACGCCTTCCAGGCGCTGCTGCAGCCACAGCAGGCGCCGCCTCCGAG
CACCTTCCAGCCGCCCGGCGCGGGCTTCCCGTACGGCGGGGGCGCCCTGCAGCCGTCGCCTCAGCAGCTCTACGGCGGCTACCAGGCCAG
CCAAGGCAGCGATGATGACTGGGACGACGAGTGGGACGACAGCTCCACGGTGGCGGACGAGCCGGGCGCTCTGGGCAGCGGAGCATACCC
GGACCTCGACGGCTCGTCTTCGGCGGGTGTGGGCGCAGCCGGCCGCTACCGCCTGTCCACGCGCTCCGACCTGTCCCTGGGTTCCCGCGG
CGGCTCGGTCCCCCCGCAGCACCACCCGTCGGGGCCCAAGAGCTCGGCCACCGTGAGCCGCAACCTCAATCGCTTCTCCACCTTCGTCAA
GTCCGGCGGGGAGGCCTTCGTGCTGGGGGAGGCGTCAGGCTTCGTGAAGGACGGGGACAAGCTGTGCGTGGTGCTGGGGCCCTATGGCCC
CGAGTGGCAGGAGAACCCCTACCCGTTCCAGTGCACCATCGACGACCCCACCAAGCAGACCAAGTTCAAGGGCATGAAGAGCTACATCTC
CTACAAGCTGGTGCCCACGCACACGCAGGTGCCGGTGCATCGGCGCTACAAGCACTTCGACTGGCTGTACGCGCGCCTGGCGGAGAAGTT
CCCGGTCATCTCCGTGCCCCACCTGCCCGAGAAGCAGGCCACCGGCCGCTTCGAGGAGGACTTCATCTCTAAGCGCAGGAAGGGCCTGAT
CTGGTGGATGAACCACATGGCCAGCCACCCAGTGCTGGCGCAGTGCGACGTCTTCCAGCACTTCCTGACGTGCCCCAGCAGCACCGACGA
GAAAGCCTGGAAGCAGGGCAAGAGGAAGGCCGAGAAGGACGAGATGGTGGGCGCCAACTTCTTCCTGACCCTTAGCACGCCCCCCGCCGC
TGCCCTTGACCTGCAGGAGGTGGAGAGCAAGATCGACGGCTTCAAGTGCTTCACCAAGAAGATGGACGACAGCGCGCTGCAGCTCAACCA
CACGGCCAACGAGTTCGCGCGCAAGCAGGTGACCGGCTTCAAAAAGGAGTATCAGAAGGTGGGCCAGTCCTTCCGCGGCCTCAGCCAGGC
CTTTGAGCTGGACCAGCAGGCCTTCTCGGTGGGCCTGAACCAGGCTATCGCCTTCACCGGAGATGCCTATGACGCCATTGGCGAGCTCTT
CGCGGAGCAGCCCAGGCAGGACCTGGATCCCGTCATGGACCTATTAGCGCTGTATCAGGGGCATCTGGCTAACTTCCCGGACATCATCCA
CGTTCAGAAAGGTGACTCATCTGAGGAAGTTGACCTGACCATGGTTTATCAAGCAGCCTCTAATGGAGATGTCAATGCTCTGACTGCAGT
GATTCGGGAAGACCCTTCTATCCTAGAATGCTGTGACAGTGAAGGATGCACGCCCTTGATGCATGCGGTTTCTGGACGTCAAGCGGACAC
AGTGAAGCTGCTGTTGAAGATGGGAGCCAATATTAACATGCAGGATGCTTATGGCCGCACAAGTTTATGCCTGGCCACCTACCTGGGCTG
GCTTGAAGGCTGTGTGAGTCTACTCAGAAACGGTGCCAAGCACAATATCCCAGATAAAAATGGCCGCCTGCCACTGCATGCTGCCACTGC
TGAGCCCGATATGAGGCTCCTCACGGTCCTGTTGCAACAGTCGAACATCAGCGAGATTAATCACCAGGACAATGAGGGAATGACACCACT
CCACTGGGCGGCTTTCCACAACCAGCCTCAACACACACAAATGCTGCTGAAGAAGGGGGCAGACCCCACCCTTGTGGATAAAGACTTTAA
AACCGCTCTCCACTGGGCAGTCCAGAGTGGAAATAGGATTCTGTGCTCCATCATTCTGAGCCATCACCAGGGGCCGTCCATAATCAACTA
TGATGATGAGAGTGGGAAGACATGTGTACATATCGCAGCGGCAGCGGGCTTCAGCGATATTATTCATGAGCTGGCAAGAGTCCCTGAGTG
TAACCTGCAGGCTCTGGATGTGGATGACAGGACACCTCTGCACTGGGCTGCAGCTGCAGGGAAGGCCGAATGTGTCCAGTCACTGCTGGA
GTTGGGAATGGACAGCAACCTGCGGGACATCAATGAGAGCACGCCCTTGGCCTATGCCCTGTACTGCGGTCACACGGCGTGTGTCAAACT
CCTCTCCCAAGAGAGCAGAACAGAGCCTACTCGACCCCCTCCCTCCCAGAGCAGTCGGCCCCAGAAGAAGGAGAGACGGTTCAACGTGCT
CAACCAAATATTCTGCAAAAACAAGAAAGAAGAGCAGAGAGCCCATCAGAAGGATCCCAGCAGGGACCGATACAGAGAGGAGGACACCTC
AGAAGTCAATGACATCATCACCACCTTTGATAGCATCGTGGGTACCAACTGCCAAGAACAGCCTGGTGATCAGGTGGCTATGGTTGAATT
TAAGAAGAAAACCTCAGACAATTCAAAATATCTCTTACCAGAAAAGAAACCGCTGGCCCGTAAGGGGCTTCCACCAATCAGAACGCAGAG
TCTCCCACCCATCACCCTGGGCAATAACTTCCTAACAGCCTCCCATAGGGCCACTTCCCATGCAGGCCTGAGCTCTGCTCCTCATCATAT
GGCCCAGCGATCTCAGAAAAGTCGAAGTGAGCAGGATTTATTAAATAACAGAACTGGCTGCCAGATGTTACTAGATAACCCCTGGAAGAG
TGATTCTAATCAGGTATTTTCCTACAAAGTTTGGACTGTGTCTTCTTCTGATAAGCTGCTGGACAGATTGCTCAGTGTCCGGCCTGGTCA
CCAAGAGGTCTCCGTGCCACCACACCTTCGCCATCTACATAATCCATCATCAGGACAAAATTTTCAGCATCTTTCCCCAAACAGACACAA
AATCAGGGATCTTCCTTTCACTCGGAACAACCTAGCTCCCCTACCAGATCAAAAATTTCTATCTGGAGAACCTCTGCGGACAAACCGAGT
GCTTCCTGCAATTCCAAGTCAACGAAGACACAGCACAGCAGCAGAAGAGAGTGAACATTCTGCCAACCCCACCAGTGATGAAAATTAACT
GTGGGCCACTCGCTGCAGAAATGTAGATGAATATGTATTTTCAACTCTCAAAGGACAAGATTACTCCAGTTTGTAAGAACGAAGACCAAT
TTAGTAAGCTGCATTCTATAAGCCATCAGTTTTATAACTCGAAATTCTTTATTCCAAATAAAGATACTCCCTAAATAAGCACTTAGAATA
TTTGGGTGTGCATATTAAGTCTGTGAATTTCTGTGACTTCCACATGCCAAAATTAAAAGACAAAATATGTTATCAGTAGGAAAACTGAGC
TATGTTTGGTTTGCTTTGTGGCATGTGCACTGTTTTTTTGTTATTGTTCTTTGGTTGTTTTTTTGCTGAATGATTTTATGTTTTGGGAAA
AAAAGTACGCTTTGCTGAATAAAAGCAAAAAACAAAACAAAAAAAAAACCACATCCCAGACAAACATGTCTTCACATTTATTGTCATTCT

>84898_84898_3_SNX18-ANKRD55_SNX18_chr5_53815403_ENST00000381410_ANKRD55_chr5_55479461_ENST00000341048_length(amino acids)=1197AA_BP=602
MRSGGAASGAARRARPAGPGSVGLPPSGLQSARQGSSSTAGPSGGPRLGTPGVGTASRGAGTMALRARALYDFRSENPGEISLREHEVLS
LCSEQDIEGWLEGVNSRGDRGLFPASYVQVIRAPEPGPAGDGGPGAPARYANVPPGGFEPLPVAPPASFKPPPDAFQALLQPQQAPPPST
FQPPGAGFPYGGGALQPSPQQLYGGYQASQGSDDDWDDEWDDSSTVADEPGALGSGAYPDLDGSSSAGVGAAGRYRLSTRSDLSLGSRGG
SVPPQHHPSGPKSSATVSRNLNRFSTFVKSGGEAFVLGEASGFVKDGDKLCVVLGPYGPEWQENPYPFQCTIDDPTKQTKFKGMKSYISY
KLVPTHTQVPVHRRYKHFDWLYARLAEKFPVISVPHLPEKQATGRFEEDFISKRRKGLIWWMNHMASHPVLAQCDVFQHFLTCPSSTDEK
AWKQGKRKAEKDEMVGANFFLTLSTPPAAALDLQEVESKIDGFKCFTKKMDDSALQLNHTANEFARKQVTGFKKEYQKVGQSFRGLSQAF
ELDQQAFSVGLNQAIAFTGDAYDAIGELFAEQPRQDLDPVMDLLALYQGHLANFPDIIHVQKGDSSEEVDLTMVYQAASNGDVNALTAVI
REDPSILECCDSEGCTPLMHAVSGRQADTVKLLLKMGANINMQDAYGRTSLCLATYLGWLEGCVSLLRNGAKHNIPDKNGRLPLHAATAE
PDMRLLTVLLQQSNISEINHQDNEGMTPLHWAAFHNQPQHTQMLLKKGADPTLVDKDFKTALHWAVQSGNRILCSIILSHHQGPSIINYD
DESGKTCVHIAAAAGFSDIIHELARVPECNLQALDVDDRTPLHWAAAAGKAECVQSLLELGMDSNLRDINESTPLAYALYCGHTACVKLL
SQESRTEPTRPPPSQSSRPQKKERRFNVLNQIFCKNKKEEQRAHQKDPSRDRYREEDTSEVNDIITTFDSIVGTNCQEQPGDQVAMVEFK
KKTSDNSKYLLPEKKPLARKGLPPIRTQSLPPITLGNNFLTASHRATSHAGLSSAPHHMAQRSQKSRSEQDLLNNRTGCQMLLDNPWKSD
SNQVFSYKVWTVSSSDKLLDRLLSVRPGHQEVSVPPHLRHLHNPSSGQNFQHLSPNRHKIRDLPFTRNNLAPLPDQKFLSGEPLRTNRVL

--------------------------------------------------------------
>84898_84898_4_SNX18-ANKRD55_SNX18_chr5_53815403_ENST00000381410_ANKRD55_chr5_55479461_ENST00000504958_length(transcript)=3879nt_BP=1811nt
GGCGCTGCGAAGTGGAGGCGCTGCGAGCGGAGCCGCGCGGAGGGCGCGACCGGCTGGTCCGGGCAGCGTGGGTTTGCCGCCTTCGGGGCT
CCAGTCCGCGCGCCAGGGCTCGAGCAGTACCGCGGGCCCCTCAGGTGGGCCTCGGCTCGGGACGCCGGGAGTCGGGACCGCCAGTCGGGG
CGCCGGGACCATGGCGCTGCGCGCCCGGGCGCTGTACGACTTCAGGTCGGAGAACCCAGGAGAGATCTCGCTGCGAGAGCACGAGGTGCT
GAGCCTGTGCAGCGAGCAGGACATCGAGGGCTGGCTCGAGGGGGTCAACAGCCGCGGCGACCGCGGCCTCTTCCCGGCCTCCTATGTGCA
GGTGATCCGCGCCCCCGAGCCTGGCCCGGCGGGAGACGGCGGCCCGGGCGCCCCGGCCCGCTACGCCAATGTGCCCCCCGGGGGCTTCGA
GCCCCTGCCTGTCGCGCCCCCCGCCTCCTTCAAGCCGCCGCCTGACGCCTTCCAGGCGCTGCTGCAGCCACAGCAGGCGCCGCCTCCGAG
CACCTTCCAGCCGCCCGGCGCGGGCTTCCCGTACGGCGGGGGCGCCCTGCAGCCGTCGCCTCAGCAGCTCTACGGCGGCTACCAGGCCAG
CCAAGGCAGCGATGATGACTGGGACGACGAGTGGGACGACAGCTCCACGGTGGCGGACGAGCCGGGCGCTCTGGGCAGCGGAGCATACCC
GGACCTCGACGGCTCGTCTTCGGCGGGTGTGGGCGCAGCCGGCCGCTACCGCCTGTCCACGCGCTCCGACCTGTCCCTGGGTTCCCGCGG
CGGCTCGGTCCCCCCGCAGCACCACCCGTCGGGGCCCAAGAGCTCGGCCACCGTGAGCCGCAACCTCAATCGCTTCTCCACCTTCGTCAA
GTCCGGCGGGGAGGCCTTCGTGCTGGGGGAGGCGTCAGGCTTCGTGAAGGACGGGGACAAGCTGTGCGTGGTGCTGGGGCCCTATGGCCC
CGAGTGGCAGGAGAACCCCTACCCGTTCCAGTGCACCATCGACGACCCCACCAAGCAGACCAAGTTCAAGGGCATGAAGAGCTACATCTC
CTACAAGCTGGTGCCCACGCACACGCAGGTGCCGGTGCATCGGCGCTACAAGCACTTCGACTGGCTGTACGCGCGCCTGGCGGAGAAGTT
CCCGGTCATCTCCGTGCCCCACCTGCCCGAGAAGCAGGCCACCGGCCGCTTCGAGGAGGACTTCATCTCTAAGCGCAGGAAGGGCCTGAT
CTGGTGGATGAACCACATGGCCAGCCACCCAGTGCTGGCGCAGTGCGACGTCTTCCAGCACTTCCTGACGTGCCCCAGCAGCACCGACGA
GAAAGCCTGGAAGCAGGGCAAGAGGAAGGCCGAGAAGGACGAGATGGTGGGCGCCAACTTCTTCCTGACCCTTAGCACGCCCCCCGCCGC
TGCCCTTGACCTGCAGGAGGTGGAGAGCAAGATCGACGGCTTCAAGTGCTTCACCAAGAAGATGGACGACAGCGCGCTGCAGCTCAACCA
CACGGCCAACGAGTTCGCGCGCAAGCAGGTGACCGGCTTCAAAAAGGAGTATCAGAAGGTGGGCCAGTCCTTCCGCGGCCTCAGCCAGGC
CTTTGAGCTGGACCAGCAGGCCTTCTCGGTGGGCCTGAACCAGGCTATCGCCTTCACCGGAGATGCCTATGACGCCATTGGCGAGCTCTT
CGCGGAGCAGCCCAGGCAGGACCTGGATCCCGTCATGGACCTATTAGCGCTGTATCAGGGGCATCTGGCTAACTTCCCGGACATCATCCA
CGTTCAGAAAGGTGACTCATCTGAGGAAGTTGACCTGACCATGGTTTATCAAGCAGCCTCTAATGGAGATGTCAATGCTCTGACTGCAGT
GATTCGGGAAGACCCTTCTATCCTAGAATGCTGTGACAGTGAAGGATGCACGCCCTTGATGCATGCGGTTTCTGGACGTCAAGCGGACAC
AGTGAAGCTGCTGTTGAAGATGGGAGCCAATATTAACATGCAGGATGCTTATGGCCGCACAAGTTTATGCCTGGCCACCTACCTGGGCTG
GCTTGAAGGCTGTGTGAGTCTACTCAGAAACGGTGCCAAGCACAATATCCCAGATAAAAATGGCCGCCTGCCACTGCATGCTGCCACTGC
TGAGCCCGATATGAGGCTCCTCACGGTCCTGTTGCAACAGTCGAACATCAGCGAGATTAATCACCAGGACAATGAGAGTGGAAATAGGAT
TCTGTGCTCCATCATTCTGAGCCATCACCAGGGGCCGTCCATAATCAACTATGATGATGAGAGTGGGAAGACATGTGTACATATCGCAGC
GGCAGCGGGCTTCAGCGATATTATTCATGAGCTGGCAAGAGTCCCTGAGTGTAACCTGCAGGCTCTGGATGTGGATGACAGGACACCTCT
GCACTGGGCTGCAGCTGCAGGGAAGGCCGAATGTGTCCAGTCACTGCTGGAGTTGGGAATGGACAGCAACCTGCGGGACATCAATGAGAG
CACGCCCTTGGCCTATGCCCTGTACTGCGGTCACACGGCGTGTGTCAAACTCCTCTCCCAAGAGAGCAGAACAGAGCCTACTCGACCCCC
TCCCTCCCAGAGCAGTCGGCCCCAGAAGAAGGAGAGACGGTTCAACGTGCTCAACCAAATATTCTGCAAAAACAAGAAAGAAGAGCAGAG
AGCCCATCAGAAGGATCCCAGCAGGGACCGATACAGAGAGGAGGACACCTCAGAAGTCAATGACATCATCACCACCTTTGATAGCATCGT
GGGTACCAACTGCCAAGAACAGCCTGGTGATCAGGTGGCTATGGTTGAATTTAAGAAGAAAACCTCAGACAATTCAAAATATCTCTTACC
AGAAAAGAAACCGCTGGCCCGTAAGGGGCTTCCACCAATCAGAACGCAGAGTCTCCCACCCATCACCCTGGGCAATAACTTCCTAACAGC
CTCCCATAGGGCCACTTCCCATGCAGGCCTGAGCTCTGCTCCTCATCATATGGCCCAGCGATCTCAGAAAAGTCGAAGTGAGCAGGATTT
ATTAAATAACAGAACTGGCTGCCAGATGTTACTAGATAACCCCTGGAAGAGTGATTCTAATCAGGTATTTTCCTACAAAGTTTGGACTGT
GTCTTCTTCTGATAAGCTGCTGGACAGATTGCTCAGTGTCCGGCCTGGTCACCAAGAGGTCTCCGTGCCACCACACCTTCGCCATCTACA
TAATCCATCATCAGGACAAAATTTTCAGCATCTTTCCCCAAACAGACACAAAATCAGGGATCTTCCTTTCACTCGGAACAACCTAGCTCC
CCTACCAGATCAAAAATTTCTATCTGGAGAACCTCTGCGGACAAACCGAGTGCTTCCTGCAATTCCAAGTCAACGAAGACACAGCACAGC
AGCAGAAGAGAGTGAACATTCTGCCAACCCCACCAGTGATGAAAATTAACTGTGGGCCACTCGCTGCAGAAATGTAGATGAATATGTATT
TTCAACTCTCAAAGGACAAGATTACTCCAGTTTGTAAGAACGAAGACCAATTTAGTAAGCTGCATTCTATAAGCCATCAGTTTTATAACT
CGAAATTCTTTATTCCAAATAAAGATACTCCCTAAATAAGCACTTAGAATATTTGGGTGTGCATATTAAGTCTGTGAATTTCTGTGACTT
CCACATGCCAAAATTAAAAGACAAAATATGTTATCAGTAGGAAAACTGAGCTATGTTTGGTTTGCTTTGTGGCATGTGCACTGTTTTTTT
GTTATTGTTCTTTGGTTGTTTTTTTGCTGAATGATTTTATGTTTTGGGAAAAAAAGTACGCTTTGCTGAATAAAAGCAAAAAACAAAACA

>84898_84898_4_SNX18-ANKRD55_SNX18_chr5_53815403_ENST00000381410_ANKRD55_chr5_55479461_ENST00000504958_length(amino acids)=1154AA_BP=602
MRSGGAASGAARRARPAGPGSVGLPPSGLQSARQGSSSTAGPSGGPRLGTPGVGTASRGAGTMALRARALYDFRSENPGEISLREHEVLS
LCSEQDIEGWLEGVNSRGDRGLFPASYVQVIRAPEPGPAGDGGPGAPARYANVPPGGFEPLPVAPPASFKPPPDAFQALLQPQQAPPPST
FQPPGAGFPYGGGALQPSPQQLYGGYQASQGSDDDWDDEWDDSSTVADEPGALGSGAYPDLDGSSSAGVGAAGRYRLSTRSDLSLGSRGG
SVPPQHHPSGPKSSATVSRNLNRFSTFVKSGGEAFVLGEASGFVKDGDKLCVVLGPYGPEWQENPYPFQCTIDDPTKQTKFKGMKSYISY
KLVPTHTQVPVHRRYKHFDWLYARLAEKFPVISVPHLPEKQATGRFEEDFISKRRKGLIWWMNHMASHPVLAQCDVFQHFLTCPSSTDEK
AWKQGKRKAEKDEMVGANFFLTLSTPPAAALDLQEVESKIDGFKCFTKKMDDSALQLNHTANEFARKQVTGFKKEYQKVGQSFRGLSQAF
ELDQQAFSVGLNQAIAFTGDAYDAIGELFAEQPRQDLDPVMDLLALYQGHLANFPDIIHVQKGDSSEEVDLTMVYQAASNGDVNALTAVI
REDPSILECCDSEGCTPLMHAVSGRQADTVKLLLKMGANINMQDAYGRTSLCLATYLGWLEGCVSLLRNGAKHNIPDKNGRLPLHAATAE
PDMRLLTVLLQQSNISEINHQDNESGNRILCSIILSHHQGPSIINYDDESGKTCVHIAAAAGFSDIIHELARVPECNLQALDVDDRTPLH
WAAAAGKAECVQSLLELGMDSNLRDINESTPLAYALYCGHTACVKLLSQESRTEPTRPPPSQSSRPQKKERRFNVLNQIFCKNKKEEQRA
HQKDPSRDRYREEDTSEVNDIITTFDSIVGTNCQEQPGDQVAMVEFKKKTSDNSKYLLPEKKPLARKGLPPIRTQSLPPITLGNNFLTAS
HRATSHAGLSSAPHHMAQRSQKSRSEQDLLNNRTGCQMLLDNPWKSDSNQVFSYKVWTVSSSDKLLDRLLSVRPGHQEVSVPPHLRHLHN

--------------------------------------------------------------

Top

Fusion Gene PPI Analysis for SNX18-ANKRD55

Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in
ChiPPI page.

Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)

Hgene

Hgene's interactors

Tgene

Tgene's interactors

- Retained PPIs in in-frame fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Still interaction with

- Lost PPIs in in-frame fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Interaction lost with

- Retained PPIs, but lost function due to frame-shift fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Interaction lost with

Top

Related Drugs for SNX18-ANKRD55

Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)

Partner

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

Top

Related Diseases for SNX18-ANKRD55

Diseases associated with fusion partners.
(DisGeNet 4.0)

Partner

Gene

Disease ID

Disease name

# pubmeds

Source