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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:SNX29-CIITA (FusionGDB2 ID:84946)

Fusion Gene Summary for SNX29-CIITA

check button Fusion gene summary
Fusion gene informationFusion gene name: SNX29-CIITA
Fusion gene ID: 84946
HgeneTgene
Gene symbol

SNX29

CIITA

Gene ID

92017

4261

Gene namesorting nexin 29class II major histocompatibility complex transactivator
SynonymsA-388D4.1|RUNDC2AC2TA|CIITAIV|MHC2TA|NLRA
Cytomap

16p13.13-p13.12

16p13.13

Type of geneprotein-codingprotein-coding
Descriptionsorting nexin-29RUN domain containing 2ARUN domain-containing protein 2AMHC class II transactivatorMHC class II transactivator type IMHC class II transactivator type IIINLR family, acid domain containingnucleotide-binding oligomerization domain, leucine rich repeat and acid domain containing
Modification date2020031320200320
UniProtAcc.

P33076

Ensembl transtripts involved in fusion geneENST00000306030, ENST00000323433, 
ENST00000566228, ENST00000568359, 
ENST00000537380, ENST00000324288, 
ENST00000381835, 
Fusion gene scores* DoF score21 X 18 X 11=41587 X 7 X 6=294
# samples 257
** MAII scorelog2(25/4158*10)=-4.05588975819628
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(7/294*10)=-2.0703893278914
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: SNX29 [Title/Abstract] AND CIITA [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointSNX29(12172772)-CIITA(10989139), # samples:3
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
TgeneCIITA

GO:0034341

response to interferon-gamma

19041327

TgeneCIITA

GO:0045345

positive regulation of MHC class I biosynthetic process

20639463

TgeneCIITA

GO:0045892

negative regulation of transcription, DNA-templated

19041327

TgeneCIITA

GO:0045893

positive regulation of transcription, DNA-templated

19041327

TgeneCIITA

GO:0045944

positive regulation of transcription by RNA polymerase II

20639463

TgeneCIITA

GO:0046677

response to antibiotic

107465


check buttonFusion gene breakpoints across SNX29 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across CIITA (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4CESCTCGA-C5-A1MJ-01ASNX29chr16

12172772

-CIITAchr16

10989139

+
ChimerDB4CESCTCGA-C5-A1MJ-01ASNX29chr16

12172772

+CIITAchr16

10989139

+


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Fusion Gene ORF analysis for SNX29-CIITA

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-3UTRENST00000306030ENST00000537380SNX29chr16

12172772

+CIITAchr16

10989139

+
5CDS-3UTRENST00000323433ENST00000537380SNX29chr16

12172772

+CIITAchr16

10989139

+
5CDS-3UTRENST00000566228ENST00000537380SNX29chr16

12172772

+CIITAchr16

10989139

+
In-frameENST00000306030ENST00000324288SNX29chr16

12172772

+CIITAchr16

10989139

+
In-frameENST00000306030ENST00000381835SNX29chr16

12172772

+CIITAchr16

10989139

+
In-frameENST00000323433ENST00000324288SNX29chr16

12172772

+CIITAchr16

10989139

+
In-frameENST00000323433ENST00000381835SNX29chr16

12172772

+CIITAchr16

10989139

+
In-frameENST00000566228ENST00000324288SNX29chr16

12172772

+CIITAchr16

10989139

+
In-frameENST00000566228ENST00000381835SNX29chr16

12172772

+CIITAchr16

10989139

+
intron-3CDSENST00000568359ENST00000324288SNX29chr16

12172772

+CIITAchr16

10989139

+
intron-3CDSENST00000568359ENST00000381835SNX29chr16

12172772

+CIITAchr16

10989139

+
intron-3UTRENST00000568359ENST00000537380SNX29chr16

12172772

+CIITAchr16

10989139

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000566228SNX29chr1612172772+ENST00000324288CIITAchr1610989139+1072414716948111580
ENST00000566228SNX29chr1612172772+ENST00000381835CIITAchr1610989139+36421471693059996
ENST00000323433SNX29chr1612172772+ENST00000324288CIITAchr1610989139+95563032936431204
ENST00000323433SNX29chr1612172772+ENST00000381835CIITAchr1610989139+2474303291891620
ENST00000306030SNX29chr1612172772+ENST00000324288CIITAchr1610989139+95563032936431204
ENST00000306030SNX29chr1612172772+ENST00000381835CIITAchr1610989139+2474303291891620

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000566228ENST00000324288SNX29chr1612172772+CIITAchr1610989139+0.0013994850.99860054
ENST00000566228ENST00000381835SNX29chr1612172772+CIITAchr1610989139+0.0050381860.99496186
ENST00000323433ENST00000324288SNX29chr1612172772+CIITAchr1610989139+0.0012237960.99877614
ENST00000323433ENST00000381835SNX29chr1612172772+CIITAchr1610989139+0.018424510.9815755
ENST00000306030ENST00000324288SNX29chr1612172772+CIITAchr1610989139+0.0012237960.99877614
ENST00000306030ENST00000381835SNX29chr1612172772+CIITAchr1610989139+0.018424510.9815755

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Fusion Genomic Features for SNX29-CIITA


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
SNX29chr1612172772+CIITAchr1610989138+1.14E-050.9999887
SNX29chr1612172772+CIITAchr1610989138+1.14E-050.9999887

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for SNX29-CIITA


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr16:12172772/chr16:10989139)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
.CIITA

P33076

FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Essential for transcriptional activity of the HLA class II promoter; activation is via the proximal promoter. No DNA binding of in vitro translated CIITA was detected. May act in a coactivator-like fashion through protein-protein interactions by contacting factors binding to the proximal MHC class II promoter, to elements of the transcription machinery, or both. Alternatively it may activate HLA class II transcription by modifying proteins that bind to the MHC class II promoter. Also mediates enhanced MHC class I transcription; the promoter element requirements for CIITA-mediated transcription are distinct from those of constitutive MHC class I transcription, and CIITA can functionally replace TAF1 at these genes. Activates CD74 transcription (PubMed:32855215). Exhibits intrinsic GTP-stimulated acetyltransferase activity. Exhibits serine/threonine protein kinase activity: can phosphorylate the TFIID component TAF7, the RAP74 subunit of the general transcription factor TFIIF, histone H2B at 'Ser-37' and other histones (in vitro). Has antiviral activity against Ebola virus and coronaviruses, including SARS-CoV-2. Induces resistance by up-regulation of the p41 isoform of CD74, which blocks cathepsin-mediated cleavage of viral glycoproteins, thereby preventing viral fusion (PubMed:32855215). {ECO:0000269|PubMed:11172716, ECO:0000269|PubMed:16600381, ECO:0000269|PubMed:17493635, ECO:0000269|PubMed:24036077, ECO:0000269|PubMed:32855215}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneSNX29chr16:12172772chr16:10989139ENST00000566228+112136_180467814.0DomainRUN
TgeneCIITAchr16:12172772chr16:10989139ENST0000032428802052_137173032.6666666666665Compositional biasNote=Asp/Glu-rich (acidic)
TgeneCIITAchr16:12172772chr16:10989139ENST00000324288020414_724173032.6666666666665DomainNACHT
TgeneCIITAchr16:12172772chr16:10989139ENST00000324288020420_427173032.6666666666665Nucleotide bindingNote=GTP
TgeneCIITAchr16:12172772chr16:10989139ENST0000032428802094_132173032.6666666666665RegionNote=Required for acetyltransferase activity
TgeneCIITAchr16:12172772chr16:10989139ENST000003242880201016_1037173032.6666666666665RepeatNote=LRR 2
TgeneCIITAchr16:12172772chr16:10989139ENST000003242880201045_1066173032.6666666666665RepeatNote=LRR 3
TgeneCIITAchr16:12172772chr16:10989139ENST000003242880201073_1093173032.6666666666665RepeatNote=LRR 4
TgeneCIITAchr16:12172772chr16:10989139ENST00000324288020985_1008173032.6666666666665RepeatNote=LRR 1

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneSNX29chr16:12172772chr16:10989139ENST00000566228+1121466_545467814.0Coiled coilOntology_term=ECO:0000255
HgeneSNX29chr16:12172772chr16:10989139ENST00000566228+1121656_779467814.0DomainPX


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Fusion Gene Sequence for SNX29-CIITA


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>84946_84946_1_SNX29-CIITA_SNX29_chr16_12172772_ENST00000306030_CIITA_chr16_10989139_ENST00000324288_length(transcript)=9556nt_BP=303nt
GGGGCCACTCGGAGTCGCCCGAGAAGCCACTGGAAGGGAACACCTGCCTCTCCCAGATGCACAGCTGGGCTCCGCTGAAGGTGCTGCACA
ATGACTCCGACATCCTCTTCCCTGTCAGTGGCGTGGGCTCCTACAGCCCAGCAGATGCCCCCCTCGGAAGCCTGGAGAACGGGACAGGAC
CAGAGGACCACGTTCTCCCAGATCCTGGACTTCGGTACAGTGTGGAAGCCAGCTCTCCAGGCCACGGAAGTCCTCTGAGCAGCCTGTTAC
CTTCTGCCTCAGTGCCAGAGTCCATGACAATTAGCAGCTCACAGTGTGCCACCATGGAGTTGGGGCCCCTAGAAGGTGGCTACCTGGAGC
TTCTTAACAGCGATGCTGACCCCCTGTGCCTCTACCACTTCTATGACCAGATGGACCTGGCTGGAGAAGAAGAGATTGAGCTCTACTCAG
AACCCGACACAGACACCATCAACTGCGACCAGTTCAGCAGGCTGTTGTGTGACATGGAAGGTGATGAAGAGACCAGGGAGGCTTATGCCA
ATATCGCGGAACTGGACCAGTATGTCTTCCAGGACTCCCAGCTGGAGGGCCTGAGCAAGGACATTTTCAAGCACATAGGACCAGATGAAG
TGATCGGTGAGAGTATGGAGATGCCAGCAGAAGTTGGGCAGAAAAGTCAGAAAAGACCCTTCCCAGAGGAGCTTCCGGCAGACCTGAAGC
ACTGGAAGCCAGCTGAGCCCCCCACTGTGGTGACTGGCAGTCTCCTAGTGAGACCAGTGAGCGACTGCTCCACCCTGCCCTGCCTGCCAC
TGCCTGCGCTGTTCAACCAGGAGCCAGCCTCCGGCCAGATGCGCCTGGAGAAAACCGACCAGATTCCCATGCCTTTCTCCAGTTCCTCGT
TGAGCTGCCTGAATCTCCCTGAGGGACCCATCCAGTTTGTCCCCACCATCTCCACTCTGCCCCATGGGCTCTGGCAAATCTCTGAGGCTG
GAACAGGGGTCTCCAGTATATTCATCTACCATGGTGAGGTGCCCCAGGCCAGCCAAGTACCCCCTCCCAGTGGATTCACTGTCCACGGCC
TCCCAACATCTCCAGACCGGCCAGGCTCCACCAGCCCCTTCGCTCCATCAGCCACTGACCTGCCCAGCATGCCTGAACCTGCCCTGACCT
CCCGAGCAAACATGACAGAGCACAAGACGTCCCCCACCCAATGCCCGGCAGCTGGAGAGGTCTCCAACAAGCTTCCAAAATGGCCTGAGC
CGGTGGAGCAGTTCTACCGCTCACTGCAGGACACGTATGGTGCCGAGCCCGCAGGCCCGGATGGCATCCTAGTGGAGGTGGATCTGGTGC
AGGCCAGGCTGGAGAGGAGCAGCAGCAAGAGCCTGGAGCGGGAACTGGCCACCCCGGACTGGGCAGAACGGCAGCTGGCCCAAGGAGGCC
TGGCTGAGGTGCTGTTGGCTGCCAAGGAGCACCGGCGGCCGCGTGAGACACGAGTGATTGCTGTGCTGGGCAAAGCTGGTCAGGGCAAGA
GCTATTGGGCTGGGGCAGTGAGCCGGGCCTGGGCTTGTGGCCGGCTTCCCCAGTACGACTTTGTCTTCTCTGTCCCCTGCCATTGCTTGA
ACCGTCCGGGGGATGCCTATGGCCTGCAGGATCTGCTCTTCTCCCTGGGCCCACAGCCACTCGTGGCGGCCGATGAGGTTTTCAGCCACA
TCTTGAAGAGACCTGACCGCGTTCTGCTCATCCTAGACGGCTTCGAGGAGCTGGAAGCGCAAGATGGCTTCCTGCACAGCACGTGCGGAC
CGGCACCGGCGGAGCCCTGCTCCCTCCGGGGGCTGCTGGCCGGCCTTTTCCAGAAGAAGCTGCTCCGAGGTTGCACCCTCCTCCTCACAG
CCCGGCCCCGGGGCCGCCTGGTCCAGAGCCTGAGCAAGGCCGACGCCCTATTTGAGCTGTCCGGCTTCTCCATGGAGCAGGCCCAGGCAT
ACGTGATGCGCTACTTTGAGAGCTCAGGGATGACAGAGCACCAAGACAGAGCCCTGACGCTCCTCCGGGACCGGCCACTTCTTCTCAGTC
ACAGCCACAGCCCTACTTTGTGCCGGGCAGTGTGCCAGCTCTCAGAGGCCCTGCTGGAGCTTGGGGAGGACGCCAAGCTGCCCTCCACGC
TCACGGGACTCTATGTCGGCCTGCTGGGCCGTGCAGCCCTCGACAGCCCCCCCGGGGCCCTGGCAGAGCTGGCCAAGCTGGCCTGGGAGC
TGGGCCGCAGACATCAAAGTACCCTACAGGAGGACCAGTTCCCATCCGCAGACGTGAGGACCTGGGCGATGGCCAAAGGCTTAGTCCAAC
ACCCACCGCGGGCCGCAGAGTCCGAGCTGGCCTTCCCCAGCTTCCTCCTGCAATGCTTCCTGGGGGCCCTGTGGCTGGCTCTGAGTGGCG
AAATCAAGGACAAGGAGCTCCCGCAGTACCTAGCATTGACCCCAAGGAAGAAGAGGCCCTATGACAACTGGCTGGAGGGCGTGCCACGCT
TTCTGGCTGGGCTGATCTTCCAGCCTCCCGCCCGCTGCCTGGGAGCCCTACTCGGGCCATCGGCGGCTGCCTCGGTGGACAGGAAGCAGA
AGGTGCTTGCGAGGTACCTGAAGCGGCTGCAGCCGGGGACACTGCGGGCGCGGCAGCTGCTGGAGCTGCTGCACTGCGCCCACGAGGCCG
AGGAGGCTGGAATTTGGCAGCACGTGGTACAGGAGCTCCCCGGCCGCCTCTCTTTTCTGGGCACCCGCCTCACGCCTCCTGATGCACATG
TACTGGGCAAGGCCTTGGAGGCGGCGGGCCAAGACTTCTCCCTGGACCTCCGCAGCACTGGCATTTGCCCCTCTGGATTGGGGAGCCTCG
TGGGACTCAGCTGTGTCACCCGTTTCAGGGCTGCCTTGAGCGACACGGTGGCGCTGTGGGAGTCCCTGCAGCAGCATGGGGAGACCAAGC
TACTTCAGGCAGCAGAGGAGAAGTTCACCATCGAGCCTTTCAAAGCCAAGTCCCTGAAGGATGTGGAAGACCTGGGAAAGCTTGTGCAGA
CTCAGAGGACGAGAAGTTCCTCGGAAGACACAGCTGGGGAGCTCCCTGCTGTTCGGGACCTAAAGAAACTGGAGTTTGCGCTGGGCCCTG
TCTCAGGCCCCCAGGCTTTCCCCAAACTGGTGCGGATCCTCACGGCCTTTTCCTCCCTGCAGCATCTGGACCTGGATGCGCTGAGTGAGA
ACAAGATCGGGGACGAGGGTGTCTCGCAGCTCTCAGCCACCTTCCCCCAGCTGAAGTCCTTGGAAACCCTCAATCTGTCCCAGAACAACA
TCACTGACCTGGGTGCCTACAAACTCGCCGAGGCCCTGCCTTCGCTCGCTGCATCCCTGCTCAGGCTAAGCTTGTACAATAACTGCATCT
GCGACGTGGGAGCCGAGAGCTTGGCTCGTGTGCTTCCGGACATGGTGTCCCTCCGGGTGATGGACGTCCAGTACAACAAGTTCACGGCTG
CCGGGGCCCAGCAGCTCGCTGCCAGCCTTCGGAGGTGTCCTCATGTGGAGACGCTGGCGATGTGGACGCCCACCATCCCATTCAGTGTCC
AGGAACACCTGCAACAACAGGATTCACGGATCAGCCTGAGATGATCCCAGCTGTGCTCTGGACAGGCATGTTCTCTGAGGACACTAACCA
CGCTGGACCTTGAACTGGGTACTTGTGGACACAGCTCTTCTCCAGGCTGTATCCCATGAGCCTCAGCATCCTGGCACCCGGCCCCTGCTG
GTTCAGGGTTGGCCCCTGCCCGGCTGCGGAATGAACCACATCTTGCTCTGCTGACAGACACAGGCCCGGCTCCAGGCTCCTTTAGCGCCC
AGTTGGGTGGATGCCTGGTGGCAGCTGCGGTCCACCCAGGAGCCCCGAGGCCTTCTCTGAAGGACATTGCGGACAGCCACGGCCAGGCCA
GAGGGAGTGACAGAGGCAGCCCCATTCTGCCTGCCCAGGCCCCTGCCACCCTGGGGAGAAAGTACTTCTTTTTTTTTATTTTTAGACAGA
GTCTCACTGTTGCCCAGGCTGGCGTGCAGTGGTGCGATCTGGGTTCACTGCAACCTCCGCCTCTTGGGTTCAAGCGATTCTTCTGCTTCA
GCCTCCCGAGTAGCTGGGACTACAGGCACCCACCATCATGTCTGGCTAATTTTTCATTTTTAGTAGAGACAGGGTTTTGCCATGTTGGCC
AGGCTGGTCTCAAACTCTTGACCTCAGGTGATCCACCCACCTCAGCCTCCCAAAGTGCTGGGATTACAAGCGTGAGCCACTGCACCGGGC
CACAGAGAAAGTACTTCTCCACCCTGCTCTCCGACCAGACACCTTGACAGGGCACACCGGGCACTCAGAAGACACTGATGGGCAACCCCC
AGCCTGCTAATTCCCCAGATTGCAACAGGCTGGGCTTCAGTGGCAGCTGCTTTTGTCTATGGGACTCAATGCACTGACATTGTTGGCCAA
AGCCAAAGCTAGGCCTGGCCAGATGCACCAGCCCTTAGCAGGGAAACAGCTAATGGGACACTAATGGGGCGGTGAGAGGGGAACAGACTG
GAAGCACAGCTTCATTTCCTGTGTCTTTTTTCACTACATTATAAATGTCTCTTTAATGTCACAGGCAGGTCCAGGGTTTGAGTTCATACC
CTGTTACCATTTTGGGGTACCCACTGCTCTGGTTATCTAATATGTAACAAGCCACCCCAAATCATAGTGGCTTAAAACAACACTCACATT
TATTCTGCTCACATATCTGTCATTTGAGCAGGGCTCAGCGGGGACAGCTCCTTCTGTCCTACTCTGTGTCAGGTGGGGCAGCTTGAGGGT
TGGGCTGGTGTCACCTGAAGACTCATTCTTCTGTACGTCTGACAGGCAATGCTGGCTGTTGGCTGGGGGCCTCAGTGCCACTACGGAATA
GTTGGCTAGGACCCCTCCATGTGGGCTAGTTGGGCTTCCTCATAGTATGGTGGCTGGGTTGGAGGGTGTCCCAAAAAGAAAGGAGGGGAT
AGAGAGAGACCACTTTTCATAACCTAGCCTTAGAAGTCACACAGTATTACTTCTGCTACATATATATGTTTTAAGAGGCAGGGTCTCACT
CTGTCGCCCAGTCTGGAATGCAGTGGTATGATCACGGCTCACTGCAGCCTCAACCTCCTGGGCTAAGTGATCCTCCCACCTCAGCCTCCC
GAATAGCTGGGACTACAGGTGTGAGTCACCAAGCCCAGTTAATCTTTAGTTTTATTTTTGTAGAGCCAGGGTCTCACTATGTTGCCCAGG
CAGGTCTTGAACTCCTGGCCTCAAGTGATTCTCCTGCCTCAGCCTCCCAAAGTGCTGGGATTACAGGTGTGAACCACCACACCCAGCCCA
CTTCTGCCATATTCTGTTGGCCAGTGTGACAAGGATTGCTACTGTCCTACCCACCCTCCTTTCACCACATGTGCACATGCACGTGTGTGC
ACGTACACACACATACACACACACGCGTGCACACACCAGAGCCCACCTTGGCTCAAGTCCTCTTTTCTGAGAGGACTTTTCTTTGTGGCT
TCCTAAAATTCAGTGGAAAATTAATTGTTTGGGGATGAGAAAGGTTGAAGCACCAAAAGCTTACCAAGGGGAATGTTTGCCTCTGCCTCT
GACACACAGCTCTGTCCTGGGAGTGAGCTGGTTTTTAGCGGAGACGGAGTCCCACCTTGGCTGCAGGGAGTCCGAAAGGGACTTGGAAGC
TCCGCTTTCTACCCAGCGAGCTGCCGGCACGACTGTTGCTTTTCACTCGGGCATAGTCTGCTCAGAAGCCCCAATTCAAGACATCTTAGC
TTACTCCTGGTGGCAGTGGGAGCTGCCTGTTCAGCTCCAGCTCACCAGCCCCAGTGCCCACAGGATCAGTCTGATTCCCAAGCTCTGCTC
CTCTCCCCAGCAAGTGAGAGCTGGGTGTCAAGAGGGTCTGAGGAATCCAGACCCGGCTGCGTGGTTGATGATCTTTGCAGACAGGCAAGC
ACCTCCTGCCTCGAACTGGCTGCAAAGGGTATCAGGTGCTGCCATCCAGGTTCAGCTTGTAAATAGCTCAGGTGTCACCCTGCAAGGGAT
CCCTGCACTTGCAGACTCTACAGAGGCCATGGGCCTCCTGTGTGTGCGCCTACAGGAGTGAGCACTAAGGTGTGCTCTGATCATCCACTG
TGCCATGTGCCAGGTTTTTGGTCTGACCCACTGCTTTTGGTCTGTGTGATGATGAAATGAGGTCAGAGCCTGCAGTTATTAACACTAACG
ATTTGTTAATGATAGCTACTGTTTATTATTTTATTTAATTTTTTTGAGACAGAGTTTTCACTCTTATTGCCCACGCTGGAGTGCAGTGGC
ATGATCTCGGCTCACTGCAACCTCTGCCTCCTGGGTTCAAGCAATTCTCCCACCTCAGCCTCCCAAGTAGCTGGGATTACAGGCATGCAC
CACCACGCCTGGCTAATTTTTGTATTTTTAGTAGAGATGGAGTTTCACCATGTTGGCCAGGCTGGTAATCTGCCTGCCTTGGCCTCCCAA
AGTGCTGGGATTACAGGGGTGAGCCACCGCACCCGGCCACTACTGTTTATTTAATGAGCAGATACATGCAAAGCCCTTATCACAGTGCAA
GGGAAATTCAAAGCGCTCAGAAAGTATTAGCTCAATAAGTGATGACTGTGTGCCAGACACTGTGCTAAACTCCTACTCAAGAGGGATAAG
AGTCTAGGGGCAAGTGGCAGAGACTCTAGAACGAGATTGCCTGGGCTCAACGCCCACCTCACCACTTACTTATGCAAGCTAGTTCTCTGT
GCCTCAGTCTCCTCATTTGTAAAATGGGCATAACCACAGCACCTTCTTTATAGGATTATGTGAAGGTGTGGTGAGCTAATACGTTAAGAA
TTGGAGCTCAATAACATGTTGGCTGTCATTATTACATATATCTGTGTTTCATTCTTGCCTCTGGCTGGAATGTTCTTCCCAGCTCTCCAT
ATGGCTGATTTCTCATCCTTCGGGACTTGCCCCATTCTCCAACCCCATCACTAGTTTTATCTTTTTCACTTATTTATGCAGTCTGCTCTT
GTCCTAGGACATGAGCTCCAGGAGGGCGGGAAACATCTCGCTTTGTACACTGCTGTGCCCTCTGTACCCAGCAAGGCGCCTGTGTATAAT
AGGTGCTCAATAACATAAAATGAACAAATAATCCTCACCTAACGGTTTCATTCATTCTGCAAATACATACTGACAGCACAGTCATGAATA
AGATGTTCCTGCCCTGGTGAGTCTTATATTTTAGCAAATTAAAAAAACTCTTTGGACAGGGCTGCCAGGTGAGGTTGGCCAGTCTGTACA
CTGCACAAAGGCACCTGGGACAAGGGGGAACATGGGGGCTGCAAACCAGTCTGGGTTCTGCTTGCCAAACTGGGAGTCCTGGTGTGGAGC
CTTTTAACCCAGAGGGGCATCTTTTCGTAGTTAACGCACAGTCATCGTAAGATGTGGATAAATTACTGTCTCCGTGTCACAGATCTAAGT
GATACTTATAGTCACACTCCTATAAAGGAATGGACTTCTGACTTCTTTGGAGGACCTCTCTGCAGGGACAGGCACAGTGTGCCGGAAGTG
CCCCTGAACCCCATTTGTCAGGTGGTAAAGCGCTGCTCGGAGGAATCAGGGCATGATAGTGCAATTCCATGTCCAGTGGATTGTAAGTCC
ACGCACCTTCCAAATGGTCACTCTTCCTCGCAGGCCTCTCTCTGCATACAAATGTCTCCCTCCTGACGCTCACCTTTTTCCCTGGGGCTC
TCAAATGTCTTCTTTTCAGATTTCGTAGCTTTTCTTTCTTTAGCATCACTTGAGGGCAAGTGGTGCTCCAACTGTCTCCCCCCAGAGTTC
TGCCGCCTGTACTCTCCCACACCTCAGTCTCCTCGCCTGTAGAAAGGGGTCAATCGTTTGAACCCTGCTTCACTTGGTGTGTATGTGAAG
GTGCTTTGAAATCAAGTGCTCTGCAAACTGGAGAGAATTACTGCTTGTATTCCGTGAAACTACAAGCTCCCAATTCCACTCATTTAATCC
CTCTCTTGCTCTGTTGCCCAGGCTGGAATGCAGTGGCATGATCTCAACTCACTGCAACCTCTGCCTCCCTGGTTTCAAGCAATTCTCCTG
CCTCAGCCTCCCGAGTAGCTGGGACTATAAGTGTGCGCCACTATGCCTGGCTAATTTTTTTGTATTTTTAGTAGAGATGGGGTTTCACCG
TGGTGGCCAGGCTGGTCTCGAACTCCTAACCTCAAGTGATCTGCCCGCCTCGGCCTTCCAAAGTGCTGGGATTACAGGCATGAGCCACCA
TGCCAAGCCCTTCCCCCCTATCTTTAATGAAGGTCTACCATGTGCCTGACACAGGGGATACCCACCCCCACTTCTATGGGATTCAGGCCT
GGTTTCCAGCTTGGCCTTCAGGCTTTTCCCACCACACCCCAAATGCTGTCCCTGGCTTGTGGAGTGGGGCAGGGGGCCAGCCTGGGACTT
TCACGCCAGCCCGACTGGGGCAGACTCTCTCAACCCCACTGGATCTTCTGCTGTTTGTCAGCCACAAGGTTCTGCCTAGAACTCCTTTCC
CGAATCTCAAAGTTAAAAAAAAAGGCAGGGCCCCAGGGGTTGGAGTTGCATACATTTTTTTTTAATCCAAAGAAGTAAGCCTCCTAAGTA
TTGCTTAGACAGGTTTATCAGAATTAAGTAGGCACAACACTCATACTTTCAGAAAAGCATTTCCAGCCAGGGGAGTAACGTGGCACTCAC
CAGCATGATGTCTGTTTTGCCAACTTGCTGAAGAACGAGTAACCTGAAATGAAGGAGCGAGAATCCCACCCTCAGCCCCCCAACAGCTTC
CTCAGCTTCTTTTTCTTCTGAGTCACCCCTGAAACAGTCGCTGCATCTAAGACCAGCCTCGGGCTAAACCCAGCTGGCCTGAAGGCTCAA
CTCACATCAAACGGAGCTGGGAGTCGCTTTTGCGTGTGTCCGCAGTTTGAAGTGTCCTCTCCGAAGGTGAAGTGGGGGAAGCAGGTGCGC
TCCGGGATGAAGTGCAGGGAGGCAAACTCTGGCTGGGTTCCTGTAAACATCCATCGCAGCTGCAAATAATCAGAAGCCAAGGCCAGGCCA
TCGATTTGACACTGCAGGCAGATGAGGTCTTGGGATGCCTCTTGCGTTCCCCCTTCTGTGGGAGCAGGTGCCTTCCCAACCTCAGCACTC
AGTCCCAATCTCTCTTCCACTCTCCTGGGTTCAAACAGGAACCTCTCTGTTGGCACGAAGCTTTTGAGGGGAGCAGGTCTAACAAGAAGG
AAAAAGGGGGGTTATTAGCACGGAAGCCCCACCCTGCCACCAGGTTGGCTGGGGACAGGGACCAATCCACCAGGCTCGGGAGGCTTGGGG
TGGGGCAGGGAAGTCTTCCTCCATCCCTCAAATTTAGGGAACCACTGGGAGCCCCAGACTCAGGCTGAAAATGTCTTTCTGCAAATATAA

>84946_84946_1_SNX29-CIITA_SNX29_chr16_12172772_ENST00000306030_CIITA_chr16_10989139_ENST00000324288_length(amino acids)=1204AA_BP=92
MEGNTCLSQMHSWAPLKVLHNDSDILFPVSGVGSYSPADAPLGSLENGTGPEDHVLPDPGLRYSVEASSPGHGSPLSSLLPSASVPESMT
ISSSQCATMELGPLEGGYLELLNSDADPLCLYHFYDQMDLAGEEEIELYSEPDTDTINCDQFSRLLCDMEGDEETREAYANIAELDQYVF
QDSQLEGLSKDIFKHIGPDEVIGESMEMPAEVGQKSQKRPFPEELPADLKHWKPAEPPTVVTGSLLVRPVSDCSTLPCLPLPALFNQEPA
SGQMRLEKTDQIPMPFSSSSLSCLNLPEGPIQFVPTISTLPHGLWQISEAGTGVSSIFIYHGEVPQASQVPPPSGFTVHGLPTSPDRPGS
TSPFAPSATDLPSMPEPALTSRANMTEHKTSPTQCPAAGEVSNKLPKWPEPVEQFYRSLQDTYGAEPAGPDGILVEVDLVQARLERSSSK
SLERELATPDWAERQLAQGGLAEVLLAAKEHRRPRETRVIAVLGKAGQGKSYWAGAVSRAWACGRLPQYDFVFSVPCHCLNRPGDAYGLQ
DLLFSLGPQPLVAADEVFSHILKRPDRVLLILDGFEELEAQDGFLHSTCGPAPAEPCSLRGLLAGLFQKKLLRGCTLLLTARPRGRLVQS
LSKADALFELSGFSMEQAQAYVMRYFESSGMTEHQDRALTLLRDRPLLLSHSHSPTLCRAVCQLSEALLELGEDAKLPSTLTGLYVGLLG
RAALDSPPGALAELAKLAWELGRRHQSTLQEDQFPSADVRTWAMAKGLVQHPPRAAESELAFPSFLLQCFLGALWLALSGEIKDKELPQY
LALTPRKKRPYDNWLEGVPRFLAGLIFQPPARCLGALLGPSAAASVDRKQKVLARYLKRLQPGTLRARQLLELLHCAHEAEEAGIWQHVV
QELPGRLSFLGTRLTPPDAHVLGKALEAAGQDFSLDLRSTGICPSGLGSLVGLSCVTRFRAALSDTVALWESLQQHGETKLLQAAEEKFT
IEPFKAKSLKDVEDLGKLVQTQRTRSSSEDTAGELPAVRDLKKLEFALGPVSGPQAFPKLVRILTAFSSLQHLDLDALSENKIGDEGVSQ
LSATFPQLKSLETLNLSQNNITDLGAYKLAEALPSLAASLLRLSLYNNCICDVGAESLARVLPDMVSLRVMDVQYNKFTAAGAQQLAASL

--------------------------------------------------------------
>84946_84946_2_SNX29-CIITA_SNX29_chr16_12172772_ENST00000306030_CIITA_chr16_10989139_ENST00000381835_length(transcript)=2474nt_BP=303nt
GGGGCCACTCGGAGTCGCCCGAGAAGCCACTGGAAGGGAACACCTGCCTCTCCCAGATGCACAGCTGGGCTCCGCTGAAGGTGCTGCACA
ATGACTCCGACATCCTCTTCCCTGTCAGTGGCGTGGGCTCCTACAGCCCAGCAGATGCCCCCCTCGGAAGCCTGGAGAACGGGACAGGAC
CAGAGGACCACGTTCTCCCAGATCCTGGACTTCGGTACAGTGTGGAAGCCAGCTCTCCAGGCCACGGAAGTCCTCTGAGCAGCCTGTTAC
CTTCTGCCTCAGTGCCAGAGTCCATGACAATTAGCAGCTCACAGTGTGCCACCATGGAGTTGGGGCCCCTAGAAGGTGGCTACCTGGAGC
TTCTTAACAGCGATGCTGACCCCCTGTGCCTCTACCACTTCTATGACCAGATGGACCTGGCTGGAGAAGAAGAGATTGAGCTCTACTCAG
AACCCGACACAGACACCATCAACTGCGACCAGTTCAGCAGGCTGTTGTGTGACATGGAAGGTGATGAAGAGACCAGGGAGGCTTATGCCA
ATATCGCGGAACTGGACCAGTATGTCTTCCAGGACTCCCAGCTGGAGGGCCTGAGCAAGGACATTTTCAAGCACATAGGACCAGATGAAG
TGATCGGTGAGAGTATGGAGATGCCAGCAGAAGTTGGGCAGAAAAGTCAGAAAAGACCCTTCCCAGAGGAGCTTCCGGCAGACCTGAAGC
ACTGGAAGCCAGTGCCTTTCTCCAGTTCCTCGTTGAGCTGCCTGAATCTCCCTGAGGGACCCATCCAGTTTGTCCCCACCATCTCCACTC
TGCCCCATGGGCTCTGGCAAATCTCTGAGGCTGGAACAGGGGTCTCCAGTATATTCATCTACCATGGTGAGGTGCCCCAGGCCAGCCAAG
TACCCCCTCCCAGTGGATTCACTGTCCACGGCCTCCCAACATCTCCAGACCGGCCAGGCTCCACCAGCCCCTTCGCTCCATCAGCCACTG
ACCTGCCCAGCATGCCTGAACCTGCCCTGACCTCCCGAGCAAACATGACAGAGCACAAGACGTCCCCCACCCAATGCCCGGCAGCTGGAG
AGGTCTCCAACAAGCTTCCAAAATGGCCTGGTCTAGCCTGGTCACCGTGCCTGGGTCTGAGGCCCTCCCTCCACAGGGCTGCCTTGAGCG
ACACGGTGGCGCTGTGGGAGTCCCTGCAGCAGCATGGGGAGACCAAGCTACTTCAGGCAGCAGAGGAGAAGTTCACCATCGAGCCTTTCA
AAGCCAAGTCCCTGAAGGATGTGGAAGACCTGGGAAAGCTTGTGCAGACTCAGAGGACGAGAAGTTCCTCGGAAGACACAGCTGGGGAGC
TCCCTGCTGTTCGGGACCTAAAGAAACTGGAGTTTGCGCTGGGCCCTGTCTCAGGCCCCCAGGCTTTCCCCAAACTGGTGCGGATCCTCA
CGGCCTTTTCCTCCCTGCAGCATCTGGACCTGGATGCGCTGAGTGAGAACAAGATCGGGGACGAGGGTGTCTCGCAGCTCTCAGCCACCT
TCCCCCAGCTGAAGTCCTTGGAAACCCTCAATCTGTCCCAGAACAACATCACTGACCTGGGTGCCTACAAACTCGCCGAGGCCCTGCCTT
CGCTCGCTGCATCCCTGCTCAGGCTAAGCTTGTACAATAACTGCATCTGCGACGTGGGAGCCGAGAGCTTGGCTCGTGTGCTTCCGGACA
TGGTGTCCCTCCGGGTGATGGACGTCCAGTACAACAAGTTCACGGCTGCCGGGGCCCAGCAGCTCGCTGCCAGCCTTCGGAGGTGTCCTC
ATGTGGAGACGCTGGCGATGTGGACGCCCACCATCCCATTCAGTGTCCAGGAACACCTGCAACAACAGGATTCACGGATCAGCCTGAGAT
GATCCCAGCTGTGCTCTGGACAGGCATGTTCTCTGAGGACACTAACCACGCTGGACCTTGAACTGGGTACTTGTGGACACAGCTCTTCTC
CAGGCTGTATCCCATGAGCCTCAGCATCCTGGCACCCGGCCCCTGCTGGTTCAGGGTTGGCCCCTGCCCGGCTGCGGAATGAACCACATC
TTGCTCTGCTGACAGACACAGGCCCGGCTCCAGGCTCCTTTAGCGCCCAGTTGGGTGGATGCCTGGTGGCAGCTGCGGTCCACCCAGGAG
CCCCGAGGCCTTCTCTGAAGGACATTGCGGACAGCCACGGCCAGGCCAGAGGGAGTGACAGAGGCAGCCCCATTCTGCCTGCCCAGGCCC
CTGCCACCCTGGGGAGAAAGTACTTCTTTTTTTTTATTTTTAGACAGAGTCTCACTGTTGCCCAGGCTGGCGTGCAGTGGTGCGATCTGG
GTTCACTGCAACCTCCGCCTCTTGGGTTCAAGCGATTCTTCTGCTTCAGCCTCCCGAGTAGCTGGGACTACAGGCACCCACCATCATGTC

>84946_84946_2_SNX29-CIITA_SNX29_chr16_12172772_ENST00000306030_CIITA_chr16_10989139_ENST00000381835_length(amino acids)=620AA_BP=92
MEGNTCLSQMHSWAPLKVLHNDSDILFPVSGVGSYSPADAPLGSLENGTGPEDHVLPDPGLRYSVEASSPGHGSPLSSLLPSASVPESMT
ISSSQCATMELGPLEGGYLELLNSDADPLCLYHFYDQMDLAGEEEIELYSEPDTDTINCDQFSRLLCDMEGDEETREAYANIAELDQYVF
QDSQLEGLSKDIFKHIGPDEVIGESMEMPAEVGQKSQKRPFPEELPADLKHWKPVPFSSSSLSCLNLPEGPIQFVPTISTLPHGLWQISE
AGTGVSSIFIYHGEVPQASQVPPPSGFTVHGLPTSPDRPGSTSPFAPSATDLPSMPEPALTSRANMTEHKTSPTQCPAAGEVSNKLPKWP
GLAWSPCLGLRPSLHRAALSDTVALWESLQQHGETKLLQAAEEKFTIEPFKAKSLKDVEDLGKLVQTQRTRSSSEDTAGELPAVRDLKKL
EFALGPVSGPQAFPKLVRILTAFSSLQHLDLDALSENKIGDEGVSQLSATFPQLKSLETLNLSQNNITDLGAYKLAEALPSLAASLLRLS

--------------------------------------------------------------
>84946_84946_3_SNX29-CIITA_SNX29_chr16_12172772_ENST00000323433_CIITA_chr16_10989139_ENST00000324288_length(transcript)=9556nt_BP=303nt
GGGGCCACTCGGAGTCGCCCGAGAAGCCACTGGAAGGGAACACCTGCCTCTCCCAGATGCACAGCTGGGCTCCGCTGAAGGTGCTGCACA
ATGACTCCGACATCCTCTTCCCTGTCAGTGGCGTGGGCTCCTACAGCCCAGCAGATGCCCCCCTCGGAAGCCTGGAGAACGGGACAGGAC
CAGAGGACCACGTTCTCCCAGATCCTGGACTTCGGTACAGTGTGGAAGCCAGCTCTCCAGGCCACGGAAGTCCTCTGAGCAGCCTGTTAC
CTTCTGCCTCAGTGCCAGAGTCCATGACAATTAGCAGCTCACAGTGTGCCACCATGGAGTTGGGGCCCCTAGAAGGTGGCTACCTGGAGC
TTCTTAACAGCGATGCTGACCCCCTGTGCCTCTACCACTTCTATGACCAGATGGACCTGGCTGGAGAAGAAGAGATTGAGCTCTACTCAG
AACCCGACACAGACACCATCAACTGCGACCAGTTCAGCAGGCTGTTGTGTGACATGGAAGGTGATGAAGAGACCAGGGAGGCTTATGCCA
ATATCGCGGAACTGGACCAGTATGTCTTCCAGGACTCCCAGCTGGAGGGCCTGAGCAAGGACATTTTCAAGCACATAGGACCAGATGAAG
TGATCGGTGAGAGTATGGAGATGCCAGCAGAAGTTGGGCAGAAAAGTCAGAAAAGACCCTTCCCAGAGGAGCTTCCGGCAGACCTGAAGC
ACTGGAAGCCAGCTGAGCCCCCCACTGTGGTGACTGGCAGTCTCCTAGTGAGACCAGTGAGCGACTGCTCCACCCTGCCCTGCCTGCCAC
TGCCTGCGCTGTTCAACCAGGAGCCAGCCTCCGGCCAGATGCGCCTGGAGAAAACCGACCAGATTCCCATGCCTTTCTCCAGTTCCTCGT
TGAGCTGCCTGAATCTCCCTGAGGGACCCATCCAGTTTGTCCCCACCATCTCCACTCTGCCCCATGGGCTCTGGCAAATCTCTGAGGCTG
GAACAGGGGTCTCCAGTATATTCATCTACCATGGTGAGGTGCCCCAGGCCAGCCAAGTACCCCCTCCCAGTGGATTCACTGTCCACGGCC
TCCCAACATCTCCAGACCGGCCAGGCTCCACCAGCCCCTTCGCTCCATCAGCCACTGACCTGCCCAGCATGCCTGAACCTGCCCTGACCT
CCCGAGCAAACATGACAGAGCACAAGACGTCCCCCACCCAATGCCCGGCAGCTGGAGAGGTCTCCAACAAGCTTCCAAAATGGCCTGAGC
CGGTGGAGCAGTTCTACCGCTCACTGCAGGACACGTATGGTGCCGAGCCCGCAGGCCCGGATGGCATCCTAGTGGAGGTGGATCTGGTGC
AGGCCAGGCTGGAGAGGAGCAGCAGCAAGAGCCTGGAGCGGGAACTGGCCACCCCGGACTGGGCAGAACGGCAGCTGGCCCAAGGAGGCC
TGGCTGAGGTGCTGTTGGCTGCCAAGGAGCACCGGCGGCCGCGTGAGACACGAGTGATTGCTGTGCTGGGCAAAGCTGGTCAGGGCAAGA
GCTATTGGGCTGGGGCAGTGAGCCGGGCCTGGGCTTGTGGCCGGCTTCCCCAGTACGACTTTGTCTTCTCTGTCCCCTGCCATTGCTTGA
ACCGTCCGGGGGATGCCTATGGCCTGCAGGATCTGCTCTTCTCCCTGGGCCCACAGCCACTCGTGGCGGCCGATGAGGTTTTCAGCCACA
TCTTGAAGAGACCTGACCGCGTTCTGCTCATCCTAGACGGCTTCGAGGAGCTGGAAGCGCAAGATGGCTTCCTGCACAGCACGTGCGGAC
CGGCACCGGCGGAGCCCTGCTCCCTCCGGGGGCTGCTGGCCGGCCTTTTCCAGAAGAAGCTGCTCCGAGGTTGCACCCTCCTCCTCACAG
CCCGGCCCCGGGGCCGCCTGGTCCAGAGCCTGAGCAAGGCCGACGCCCTATTTGAGCTGTCCGGCTTCTCCATGGAGCAGGCCCAGGCAT
ACGTGATGCGCTACTTTGAGAGCTCAGGGATGACAGAGCACCAAGACAGAGCCCTGACGCTCCTCCGGGACCGGCCACTTCTTCTCAGTC
ACAGCCACAGCCCTACTTTGTGCCGGGCAGTGTGCCAGCTCTCAGAGGCCCTGCTGGAGCTTGGGGAGGACGCCAAGCTGCCCTCCACGC
TCACGGGACTCTATGTCGGCCTGCTGGGCCGTGCAGCCCTCGACAGCCCCCCCGGGGCCCTGGCAGAGCTGGCCAAGCTGGCCTGGGAGC
TGGGCCGCAGACATCAAAGTACCCTACAGGAGGACCAGTTCCCATCCGCAGACGTGAGGACCTGGGCGATGGCCAAAGGCTTAGTCCAAC
ACCCACCGCGGGCCGCAGAGTCCGAGCTGGCCTTCCCCAGCTTCCTCCTGCAATGCTTCCTGGGGGCCCTGTGGCTGGCTCTGAGTGGCG
AAATCAAGGACAAGGAGCTCCCGCAGTACCTAGCATTGACCCCAAGGAAGAAGAGGCCCTATGACAACTGGCTGGAGGGCGTGCCACGCT
TTCTGGCTGGGCTGATCTTCCAGCCTCCCGCCCGCTGCCTGGGAGCCCTACTCGGGCCATCGGCGGCTGCCTCGGTGGACAGGAAGCAGA
AGGTGCTTGCGAGGTACCTGAAGCGGCTGCAGCCGGGGACACTGCGGGCGCGGCAGCTGCTGGAGCTGCTGCACTGCGCCCACGAGGCCG
AGGAGGCTGGAATTTGGCAGCACGTGGTACAGGAGCTCCCCGGCCGCCTCTCTTTTCTGGGCACCCGCCTCACGCCTCCTGATGCACATG
TACTGGGCAAGGCCTTGGAGGCGGCGGGCCAAGACTTCTCCCTGGACCTCCGCAGCACTGGCATTTGCCCCTCTGGATTGGGGAGCCTCG
TGGGACTCAGCTGTGTCACCCGTTTCAGGGCTGCCTTGAGCGACACGGTGGCGCTGTGGGAGTCCCTGCAGCAGCATGGGGAGACCAAGC
TACTTCAGGCAGCAGAGGAGAAGTTCACCATCGAGCCTTTCAAAGCCAAGTCCCTGAAGGATGTGGAAGACCTGGGAAAGCTTGTGCAGA
CTCAGAGGACGAGAAGTTCCTCGGAAGACACAGCTGGGGAGCTCCCTGCTGTTCGGGACCTAAAGAAACTGGAGTTTGCGCTGGGCCCTG
TCTCAGGCCCCCAGGCTTTCCCCAAACTGGTGCGGATCCTCACGGCCTTTTCCTCCCTGCAGCATCTGGACCTGGATGCGCTGAGTGAGA
ACAAGATCGGGGACGAGGGTGTCTCGCAGCTCTCAGCCACCTTCCCCCAGCTGAAGTCCTTGGAAACCCTCAATCTGTCCCAGAACAACA
TCACTGACCTGGGTGCCTACAAACTCGCCGAGGCCCTGCCTTCGCTCGCTGCATCCCTGCTCAGGCTAAGCTTGTACAATAACTGCATCT
GCGACGTGGGAGCCGAGAGCTTGGCTCGTGTGCTTCCGGACATGGTGTCCCTCCGGGTGATGGACGTCCAGTACAACAAGTTCACGGCTG
CCGGGGCCCAGCAGCTCGCTGCCAGCCTTCGGAGGTGTCCTCATGTGGAGACGCTGGCGATGTGGACGCCCACCATCCCATTCAGTGTCC
AGGAACACCTGCAACAACAGGATTCACGGATCAGCCTGAGATGATCCCAGCTGTGCTCTGGACAGGCATGTTCTCTGAGGACACTAACCA
CGCTGGACCTTGAACTGGGTACTTGTGGACACAGCTCTTCTCCAGGCTGTATCCCATGAGCCTCAGCATCCTGGCACCCGGCCCCTGCTG
GTTCAGGGTTGGCCCCTGCCCGGCTGCGGAATGAACCACATCTTGCTCTGCTGACAGACACAGGCCCGGCTCCAGGCTCCTTTAGCGCCC
AGTTGGGTGGATGCCTGGTGGCAGCTGCGGTCCACCCAGGAGCCCCGAGGCCTTCTCTGAAGGACATTGCGGACAGCCACGGCCAGGCCA
GAGGGAGTGACAGAGGCAGCCCCATTCTGCCTGCCCAGGCCCCTGCCACCCTGGGGAGAAAGTACTTCTTTTTTTTTATTTTTAGACAGA
GTCTCACTGTTGCCCAGGCTGGCGTGCAGTGGTGCGATCTGGGTTCACTGCAACCTCCGCCTCTTGGGTTCAAGCGATTCTTCTGCTTCA
GCCTCCCGAGTAGCTGGGACTACAGGCACCCACCATCATGTCTGGCTAATTTTTCATTTTTAGTAGAGACAGGGTTTTGCCATGTTGGCC
AGGCTGGTCTCAAACTCTTGACCTCAGGTGATCCACCCACCTCAGCCTCCCAAAGTGCTGGGATTACAAGCGTGAGCCACTGCACCGGGC
CACAGAGAAAGTACTTCTCCACCCTGCTCTCCGACCAGACACCTTGACAGGGCACACCGGGCACTCAGAAGACACTGATGGGCAACCCCC
AGCCTGCTAATTCCCCAGATTGCAACAGGCTGGGCTTCAGTGGCAGCTGCTTTTGTCTATGGGACTCAATGCACTGACATTGTTGGCCAA
AGCCAAAGCTAGGCCTGGCCAGATGCACCAGCCCTTAGCAGGGAAACAGCTAATGGGACACTAATGGGGCGGTGAGAGGGGAACAGACTG
GAAGCACAGCTTCATTTCCTGTGTCTTTTTTCACTACATTATAAATGTCTCTTTAATGTCACAGGCAGGTCCAGGGTTTGAGTTCATACC
CTGTTACCATTTTGGGGTACCCACTGCTCTGGTTATCTAATATGTAACAAGCCACCCCAAATCATAGTGGCTTAAAACAACACTCACATT
TATTCTGCTCACATATCTGTCATTTGAGCAGGGCTCAGCGGGGACAGCTCCTTCTGTCCTACTCTGTGTCAGGTGGGGCAGCTTGAGGGT
TGGGCTGGTGTCACCTGAAGACTCATTCTTCTGTACGTCTGACAGGCAATGCTGGCTGTTGGCTGGGGGCCTCAGTGCCACTACGGAATA
GTTGGCTAGGACCCCTCCATGTGGGCTAGTTGGGCTTCCTCATAGTATGGTGGCTGGGTTGGAGGGTGTCCCAAAAAGAAAGGAGGGGAT
AGAGAGAGACCACTTTTCATAACCTAGCCTTAGAAGTCACACAGTATTACTTCTGCTACATATATATGTTTTAAGAGGCAGGGTCTCACT
CTGTCGCCCAGTCTGGAATGCAGTGGTATGATCACGGCTCACTGCAGCCTCAACCTCCTGGGCTAAGTGATCCTCCCACCTCAGCCTCCC
GAATAGCTGGGACTACAGGTGTGAGTCACCAAGCCCAGTTAATCTTTAGTTTTATTTTTGTAGAGCCAGGGTCTCACTATGTTGCCCAGG
CAGGTCTTGAACTCCTGGCCTCAAGTGATTCTCCTGCCTCAGCCTCCCAAAGTGCTGGGATTACAGGTGTGAACCACCACACCCAGCCCA
CTTCTGCCATATTCTGTTGGCCAGTGTGACAAGGATTGCTACTGTCCTACCCACCCTCCTTTCACCACATGTGCACATGCACGTGTGTGC
ACGTACACACACATACACACACACGCGTGCACACACCAGAGCCCACCTTGGCTCAAGTCCTCTTTTCTGAGAGGACTTTTCTTTGTGGCT
TCCTAAAATTCAGTGGAAAATTAATTGTTTGGGGATGAGAAAGGTTGAAGCACCAAAAGCTTACCAAGGGGAATGTTTGCCTCTGCCTCT
GACACACAGCTCTGTCCTGGGAGTGAGCTGGTTTTTAGCGGAGACGGAGTCCCACCTTGGCTGCAGGGAGTCCGAAAGGGACTTGGAAGC
TCCGCTTTCTACCCAGCGAGCTGCCGGCACGACTGTTGCTTTTCACTCGGGCATAGTCTGCTCAGAAGCCCCAATTCAAGACATCTTAGC
TTACTCCTGGTGGCAGTGGGAGCTGCCTGTTCAGCTCCAGCTCACCAGCCCCAGTGCCCACAGGATCAGTCTGATTCCCAAGCTCTGCTC
CTCTCCCCAGCAAGTGAGAGCTGGGTGTCAAGAGGGTCTGAGGAATCCAGACCCGGCTGCGTGGTTGATGATCTTTGCAGACAGGCAAGC
ACCTCCTGCCTCGAACTGGCTGCAAAGGGTATCAGGTGCTGCCATCCAGGTTCAGCTTGTAAATAGCTCAGGTGTCACCCTGCAAGGGAT
CCCTGCACTTGCAGACTCTACAGAGGCCATGGGCCTCCTGTGTGTGCGCCTACAGGAGTGAGCACTAAGGTGTGCTCTGATCATCCACTG
TGCCATGTGCCAGGTTTTTGGTCTGACCCACTGCTTTTGGTCTGTGTGATGATGAAATGAGGTCAGAGCCTGCAGTTATTAACACTAACG
ATTTGTTAATGATAGCTACTGTTTATTATTTTATTTAATTTTTTTGAGACAGAGTTTTCACTCTTATTGCCCACGCTGGAGTGCAGTGGC
ATGATCTCGGCTCACTGCAACCTCTGCCTCCTGGGTTCAAGCAATTCTCCCACCTCAGCCTCCCAAGTAGCTGGGATTACAGGCATGCAC
CACCACGCCTGGCTAATTTTTGTATTTTTAGTAGAGATGGAGTTTCACCATGTTGGCCAGGCTGGTAATCTGCCTGCCTTGGCCTCCCAA
AGTGCTGGGATTACAGGGGTGAGCCACCGCACCCGGCCACTACTGTTTATTTAATGAGCAGATACATGCAAAGCCCTTATCACAGTGCAA
GGGAAATTCAAAGCGCTCAGAAAGTATTAGCTCAATAAGTGATGACTGTGTGCCAGACACTGTGCTAAACTCCTACTCAAGAGGGATAAG
AGTCTAGGGGCAAGTGGCAGAGACTCTAGAACGAGATTGCCTGGGCTCAACGCCCACCTCACCACTTACTTATGCAAGCTAGTTCTCTGT
GCCTCAGTCTCCTCATTTGTAAAATGGGCATAACCACAGCACCTTCTTTATAGGATTATGTGAAGGTGTGGTGAGCTAATACGTTAAGAA
TTGGAGCTCAATAACATGTTGGCTGTCATTATTACATATATCTGTGTTTCATTCTTGCCTCTGGCTGGAATGTTCTTCCCAGCTCTCCAT
ATGGCTGATTTCTCATCCTTCGGGACTTGCCCCATTCTCCAACCCCATCACTAGTTTTATCTTTTTCACTTATTTATGCAGTCTGCTCTT
GTCCTAGGACATGAGCTCCAGGAGGGCGGGAAACATCTCGCTTTGTACACTGCTGTGCCCTCTGTACCCAGCAAGGCGCCTGTGTATAAT
AGGTGCTCAATAACATAAAATGAACAAATAATCCTCACCTAACGGTTTCATTCATTCTGCAAATACATACTGACAGCACAGTCATGAATA
AGATGTTCCTGCCCTGGTGAGTCTTATATTTTAGCAAATTAAAAAAACTCTTTGGACAGGGCTGCCAGGTGAGGTTGGCCAGTCTGTACA
CTGCACAAAGGCACCTGGGACAAGGGGGAACATGGGGGCTGCAAACCAGTCTGGGTTCTGCTTGCCAAACTGGGAGTCCTGGTGTGGAGC
CTTTTAACCCAGAGGGGCATCTTTTCGTAGTTAACGCACAGTCATCGTAAGATGTGGATAAATTACTGTCTCCGTGTCACAGATCTAAGT
GATACTTATAGTCACACTCCTATAAAGGAATGGACTTCTGACTTCTTTGGAGGACCTCTCTGCAGGGACAGGCACAGTGTGCCGGAAGTG
CCCCTGAACCCCATTTGTCAGGTGGTAAAGCGCTGCTCGGAGGAATCAGGGCATGATAGTGCAATTCCATGTCCAGTGGATTGTAAGTCC
ACGCACCTTCCAAATGGTCACTCTTCCTCGCAGGCCTCTCTCTGCATACAAATGTCTCCCTCCTGACGCTCACCTTTTTCCCTGGGGCTC
TCAAATGTCTTCTTTTCAGATTTCGTAGCTTTTCTTTCTTTAGCATCACTTGAGGGCAAGTGGTGCTCCAACTGTCTCCCCCCAGAGTTC
TGCCGCCTGTACTCTCCCACACCTCAGTCTCCTCGCCTGTAGAAAGGGGTCAATCGTTTGAACCCTGCTTCACTTGGTGTGTATGTGAAG
GTGCTTTGAAATCAAGTGCTCTGCAAACTGGAGAGAATTACTGCTTGTATTCCGTGAAACTACAAGCTCCCAATTCCACTCATTTAATCC
CTCTCTTGCTCTGTTGCCCAGGCTGGAATGCAGTGGCATGATCTCAACTCACTGCAACCTCTGCCTCCCTGGTTTCAAGCAATTCTCCTG
CCTCAGCCTCCCGAGTAGCTGGGACTATAAGTGTGCGCCACTATGCCTGGCTAATTTTTTTGTATTTTTAGTAGAGATGGGGTTTCACCG
TGGTGGCCAGGCTGGTCTCGAACTCCTAACCTCAAGTGATCTGCCCGCCTCGGCCTTCCAAAGTGCTGGGATTACAGGCATGAGCCACCA
TGCCAAGCCCTTCCCCCCTATCTTTAATGAAGGTCTACCATGTGCCTGACACAGGGGATACCCACCCCCACTTCTATGGGATTCAGGCCT
GGTTTCCAGCTTGGCCTTCAGGCTTTTCCCACCACACCCCAAATGCTGTCCCTGGCTTGTGGAGTGGGGCAGGGGGCCAGCCTGGGACTT
TCACGCCAGCCCGACTGGGGCAGACTCTCTCAACCCCACTGGATCTTCTGCTGTTTGTCAGCCACAAGGTTCTGCCTAGAACTCCTTTCC
CGAATCTCAAAGTTAAAAAAAAAGGCAGGGCCCCAGGGGTTGGAGTTGCATACATTTTTTTTTAATCCAAAGAAGTAAGCCTCCTAAGTA
TTGCTTAGACAGGTTTATCAGAATTAAGTAGGCACAACACTCATACTTTCAGAAAAGCATTTCCAGCCAGGGGAGTAACGTGGCACTCAC
CAGCATGATGTCTGTTTTGCCAACTTGCTGAAGAACGAGTAACCTGAAATGAAGGAGCGAGAATCCCACCCTCAGCCCCCCAACAGCTTC
CTCAGCTTCTTTTTCTTCTGAGTCACCCCTGAAACAGTCGCTGCATCTAAGACCAGCCTCGGGCTAAACCCAGCTGGCCTGAAGGCTCAA
CTCACATCAAACGGAGCTGGGAGTCGCTTTTGCGTGTGTCCGCAGTTTGAAGTGTCCTCTCCGAAGGTGAAGTGGGGGAAGCAGGTGCGC
TCCGGGATGAAGTGCAGGGAGGCAAACTCTGGCTGGGTTCCTGTAAACATCCATCGCAGCTGCAAATAATCAGAAGCCAAGGCCAGGCCA
TCGATTTGACACTGCAGGCAGATGAGGTCTTGGGATGCCTCTTGCGTTCCCCCTTCTGTGGGAGCAGGTGCCTTCCCAACCTCAGCACTC
AGTCCCAATCTCTCTTCCACTCTCCTGGGTTCAAACAGGAACCTCTCTGTTGGCACGAAGCTTTTGAGGGGAGCAGGTCTAACAAGAAGG
AAAAAGGGGGGTTATTAGCACGGAAGCCCCACCCTGCCACCAGGTTGGCTGGGGACAGGGACCAATCCACCAGGCTCGGGAGGCTTGGGG
TGGGGCAGGGAAGTCTTCCTCCATCCCTCAAATTTAGGGAACCACTGGGAGCCCCAGACTCAGGCTGAAAATGTCTTTCTGCAAATATAA

>84946_84946_3_SNX29-CIITA_SNX29_chr16_12172772_ENST00000323433_CIITA_chr16_10989139_ENST00000324288_length(amino acids)=1204AA_BP=92
MEGNTCLSQMHSWAPLKVLHNDSDILFPVSGVGSYSPADAPLGSLENGTGPEDHVLPDPGLRYSVEASSPGHGSPLSSLLPSASVPESMT
ISSSQCATMELGPLEGGYLELLNSDADPLCLYHFYDQMDLAGEEEIELYSEPDTDTINCDQFSRLLCDMEGDEETREAYANIAELDQYVF
QDSQLEGLSKDIFKHIGPDEVIGESMEMPAEVGQKSQKRPFPEELPADLKHWKPAEPPTVVTGSLLVRPVSDCSTLPCLPLPALFNQEPA
SGQMRLEKTDQIPMPFSSSSLSCLNLPEGPIQFVPTISTLPHGLWQISEAGTGVSSIFIYHGEVPQASQVPPPSGFTVHGLPTSPDRPGS
TSPFAPSATDLPSMPEPALTSRANMTEHKTSPTQCPAAGEVSNKLPKWPEPVEQFYRSLQDTYGAEPAGPDGILVEVDLVQARLERSSSK
SLERELATPDWAERQLAQGGLAEVLLAAKEHRRPRETRVIAVLGKAGQGKSYWAGAVSRAWACGRLPQYDFVFSVPCHCLNRPGDAYGLQ
DLLFSLGPQPLVAADEVFSHILKRPDRVLLILDGFEELEAQDGFLHSTCGPAPAEPCSLRGLLAGLFQKKLLRGCTLLLTARPRGRLVQS
LSKADALFELSGFSMEQAQAYVMRYFESSGMTEHQDRALTLLRDRPLLLSHSHSPTLCRAVCQLSEALLELGEDAKLPSTLTGLYVGLLG
RAALDSPPGALAELAKLAWELGRRHQSTLQEDQFPSADVRTWAMAKGLVQHPPRAAESELAFPSFLLQCFLGALWLALSGEIKDKELPQY
LALTPRKKRPYDNWLEGVPRFLAGLIFQPPARCLGALLGPSAAASVDRKQKVLARYLKRLQPGTLRARQLLELLHCAHEAEEAGIWQHVV
QELPGRLSFLGTRLTPPDAHVLGKALEAAGQDFSLDLRSTGICPSGLGSLVGLSCVTRFRAALSDTVALWESLQQHGETKLLQAAEEKFT
IEPFKAKSLKDVEDLGKLVQTQRTRSSSEDTAGELPAVRDLKKLEFALGPVSGPQAFPKLVRILTAFSSLQHLDLDALSENKIGDEGVSQ
LSATFPQLKSLETLNLSQNNITDLGAYKLAEALPSLAASLLRLSLYNNCICDVGAESLARVLPDMVSLRVMDVQYNKFTAAGAQQLAASL

--------------------------------------------------------------
>84946_84946_4_SNX29-CIITA_SNX29_chr16_12172772_ENST00000323433_CIITA_chr16_10989139_ENST00000381835_length(transcript)=2474nt_BP=303nt
GGGGCCACTCGGAGTCGCCCGAGAAGCCACTGGAAGGGAACACCTGCCTCTCCCAGATGCACAGCTGGGCTCCGCTGAAGGTGCTGCACA
ATGACTCCGACATCCTCTTCCCTGTCAGTGGCGTGGGCTCCTACAGCCCAGCAGATGCCCCCCTCGGAAGCCTGGAGAACGGGACAGGAC
CAGAGGACCACGTTCTCCCAGATCCTGGACTTCGGTACAGTGTGGAAGCCAGCTCTCCAGGCCACGGAAGTCCTCTGAGCAGCCTGTTAC
CTTCTGCCTCAGTGCCAGAGTCCATGACAATTAGCAGCTCACAGTGTGCCACCATGGAGTTGGGGCCCCTAGAAGGTGGCTACCTGGAGC
TTCTTAACAGCGATGCTGACCCCCTGTGCCTCTACCACTTCTATGACCAGATGGACCTGGCTGGAGAAGAAGAGATTGAGCTCTACTCAG
AACCCGACACAGACACCATCAACTGCGACCAGTTCAGCAGGCTGTTGTGTGACATGGAAGGTGATGAAGAGACCAGGGAGGCTTATGCCA
ATATCGCGGAACTGGACCAGTATGTCTTCCAGGACTCCCAGCTGGAGGGCCTGAGCAAGGACATTTTCAAGCACATAGGACCAGATGAAG
TGATCGGTGAGAGTATGGAGATGCCAGCAGAAGTTGGGCAGAAAAGTCAGAAAAGACCCTTCCCAGAGGAGCTTCCGGCAGACCTGAAGC
ACTGGAAGCCAGTGCCTTTCTCCAGTTCCTCGTTGAGCTGCCTGAATCTCCCTGAGGGACCCATCCAGTTTGTCCCCACCATCTCCACTC
TGCCCCATGGGCTCTGGCAAATCTCTGAGGCTGGAACAGGGGTCTCCAGTATATTCATCTACCATGGTGAGGTGCCCCAGGCCAGCCAAG
TACCCCCTCCCAGTGGATTCACTGTCCACGGCCTCCCAACATCTCCAGACCGGCCAGGCTCCACCAGCCCCTTCGCTCCATCAGCCACTG
ACCTGCCCAGCATGCCTGAACCTGCCCTGACCTCCCGAGCAAACATGACAGAGCACAAGACGTCCCCCACCCAATGCCCGGCAGCTGGAG
AGGTCTCCAACAAGCTTCCAAAATGGCCTGGTCTAGCCTGGTCACCGTGCCTGGGTCTGAGGCCCTCCCTCCACAGGGCTGCCTTGAGCG
ACACGGTGGCGCTGTGGGAGTCCCTGCAGCAGCATGGGGAGACCAAGCTACTTCAGGCAGCAGAGGAGAAGTTCACCATCGAGCCTTTCA
AAGCCAAGTCCCTGAAGGATGTGGAAGACCTGGGAAAGCTTGTGCAGACTCAGAGGACGAGAAGTTCCTCGGAAGACACAGCTGGGGAGC
TCCCTGCTGTTCGGGACCTAAAGAAACTGGAGTTTGCGCTGGGCCCTGTCTCAGGCCCCCAGGCTTTCCCCAAACTGGTGCGGATCCTCA
CGGCCTTTTCCTCCCTGCAGCATCTGGACCTGGATGCGCTGAGTGAGAACAAGATCGGGGACGAGGGTGTCTCGCAGCTCTCAGCCACCT
TCCCCCAGCTGAAGTCCTTGGAAACCCTCAATCTGTCCCAGAACAACATCACTGACCTGGGTGCCTACAAACTCGCCGAGGCCCTGCCTT
CGCTCGCTGCATCCCTGCTCAGGCTAAGCTTGTACAATAACTGCATCTGCGACGTGGGAGCCGAGAGCTTGGCTCGTGTGCTTCCGGACA
TGGTGTCCCTCCGGGTGATGGACGTCCAGTACAACAAGTTCACGGCTGCCGGGGCCCAGCAGCTCGCTGCCAGCCTTCGGAGGTGTCCTC
ATGTGGAGACGCTGGCGATGTGGACGCCCACCATCCCATTCAGTGTCCAGGAACACCTGCAACAACAGGATTCACGGATCAGCCTGAGAT
GATCCCAGCTGTGCTCTGGACAGGCATGTTCTCTGAGGACACTAACCACGCTGGACCTTGAACTGGGTACTTGTGGACACAGCTCTTCTC
CAGGCTGTATCCCATGAGCCTCAGCATCCTGGCACCCGGCCCCTGCTGGTTCAGGGTTGGCCCCTGCCCGGCTGCGGAATGAACCACATC
TTGCTCTGCTGACAGACACAGGCCCGGCTCCAGGCTCCTTTAGCGCCCAGTTGGGTGGATGCCTGGTGGCAGCTGCGGTCCACCCAGGAG
CCCCGAGGCCTTCTCTGAAGGACATTGCGGACAGCCACGGCCAGGCCAGAGGGAGTGACAGAGGCAGCCCCATTCTGCCTGCCCAGGCCC
CTGCCACCCTGGGGAGAAAGTACTTCTTTTTTTTTATTTTTAGACAGAGTCTCACTGTTGCCCAGGCTGGCGTGCAGTGGTGCGATCTGG
GTTCACTGCAACCTCCGCCTCTTGGGTTCAAGCGATTCTTCTGCTTCAGCCTCCCGAGTAGCTGGGACTACAGGCACCCACCATCATGTC

>84946_84946_4_SNX29-CIITA_SNX29_chr16_12172772_ENST00000323433_CIITA_chr16_10989139_ENST00000381835_length(amino acids)=620AA_BP=92
MEGNTCLSQMHSWAPLKVLHNDSDILFPVSGVGSYSPADAPLGSLENGTGPEDHVLPDPGLRYSVEASSPGHGSPLSSLLPSASVPESMT
ISSSQCATMELGPLEGGYLELLNSDADPLCLYHFYDQMDLAGEEEIELYSEPDTDTINCDQFSRLLCDMEGDEETREAYANIAELDQYVF
QDSQLEGLSKDIFKHIGPDEVIGESMEMPAEVGQKSQKRPFPEELPADLKHWKPVPFSSSSLSCLNLPEGPIQFVPTISTLPHGLWQISE
AGTGVSSIFIYHGEVPQASQVPPPSGFTVHGLPTSPDRPGSTSPFAPSATDLPSMPEPALTSRANMTEHKTSPTQCPAAGEVSNKLPKWP
GLAWSPCLGLRPSLHRAALSDTVALWESLQQHGETKLLQAAEEKFTIEPFKAKSLKDVEDLGKLVQTQRTRSSSEDTAGELPAVRDLKKL
EFALGPVSGPQAFPKLVRILTAFSSLQHLDLDALSENKIGDEGVSQLSATFPQLKSLETLNLSQNNITDLGAYKLAEALPSLAASLLRLS

--------------------------------------------------------------
>84946_84946_5_SNX29-CIITA_SNX29_chr16_12172772_ENST00000566228_CIITA_chr16_10989139_ENST00000324288_length(transcript)=10724nt_BP=1471nt
GGAGCTCGGCAGCCGCAGAAGCGGCAGCGGCGGCGGCGCGGCGCAGGCACCGGCCCGGGGAGAGGCACCATGAGCGGATCACAGAACAAT
GACAAAAGACAATTTCTGCTGGAGCGACTGCTGGATGCAGTGAAACAGTGCCAGATCCGCTTTGGAGGGAGAAAGGAGATTGCCTCGGAT
TCCGACAGCAGGGTCACCTGTCTGTGTGCCCAGTTTGAAGCCGTCCTGCAGCATGGCTTGAAGAGGAGTCGAGGATTGGCACTCACAGCG
GCAGCGATCAAGCAGGCAGCGGGCTTTGCCAGCAAAACCGAAACAGAGCCCGTGTTCTGGTACTACGTGAAGGAGGTCCTCAACAAGCAC
GAGCTGCAGCGCTTCTACTCCCTGCGCCACATCGCCTCAGACGTGGGCCGGGGTCGCGCCTGGCTGCGCTGTGCCCTCAACGAACACTCC
CTGGAGCGCTACCTGCACATGCTCCTGGCCGACCGCTGCAGGCTGAGCACTTTTTATGAAGACTGGTCTTTTGTGATGGATGAAGAAAGG
TCCAGTATGCTTCCTACCATGGCAGCAGGTCTGAACTCCATACTCTTTGCGATTAACATCGACAACAAGGATTTGAACGGGCAGAGTAAG
TTTGCTCCCACCGTTTCAGACCTCTTAAAGGAGTCAACGCAGAACGTGACCTCCTTGCTGAAGGAGTCCACGCAAGGAGTGAGCAGCCTG
TTCAGGGAGATCACAGCCTCCTCTGCCGTCTCCATCCTCATCAAACCTGAACAGGAGACCGACCCCTTGCCTGTCGTGTCCAGGAATGTC
AGTGCTGATGCCAAATGCAAAAAGGAGCGGAAGAAGAAAAAGAAAGTGACCAACATAATCTCATTTGATGATGAGGAAGATGAGCAGAAC
TCTGGGGACGTGTTTAAAAAGACACCTGGGGCAGGGGAGAGCTCAGAGGACAACTCCGACCGCTCCTCTGTCAATATCATGTCCGCCTTT
GAAAGCCCCTTCGGGCCTAACTCCAATGGAAGTCAGAGCAGCAACTCATGGAAAATTGATTCCCTGTCTTTGAACGGGGAGTTTGGGTAC
CAGAAGCTTGATGTGAAAAGCATCGATGATGAAGATGTGGATGAAAACGAAGATGACGTGTATGGAAACTCATCAGGAAGGAAGCACAGG
GGCCACTCGGAGTCGCCCGAGAAGCCACTGGAAGGGAACACCTGCCTCTCCCAGATGCACAGCTGGGCTCCGCTGAAGGTGCTGCACAAT
GACTCCGACATCCTCTTCCCTGTCAGTGGCGTGGGCTCCTACAGCCCAGCAGATGCCCCCCTCGGAAGCCTGGAGAACGGGACAGGACCA
GAGGACCACGTTCTCCCAGATCCTGGACTTCGGTACAGTGTGGAAGCCAGCTCTCCAGGCCACGGAAGTCCTCTGAGCAGCCTGTTACCT
TCTGCCTCAGTGCCAGAGTCCATGACAATTAGCAGCTCACAGTGTGCCACCATGGAGTTGGGGCCCCTAGAAGGTGGCTACCTGGAGCTT
CTTAACAGCGATGCTGACCCCCTGTGCCTCTACCACTTCTATGACCAGATGGACCTGGCTGGAGAAGAAGAGATTGAGCTCTACTCAGAA
CCCGACACAGACACCATCAACTGCGACCAGTTCAGCAGGCTGTTGTGTGACATGGAAGGTGATGAAGAGACCAGGGAGGCTTATGCCAAT
ATCGCGGAACTGGACCAGTATGTCTTCCAGGACTCCCAGCTGGAGGGCCTGAGCAAGGACATTTTCAAGCACATAGGACCAGATGAAGTG
ATCGGTGAGAGTATGGAGATGCCAGCAGAAGTTGGGCAGAAAAGTCAGAAAAGACCCTTCCCAGAGGAGCTTCCGGCAGACCTGAAGCAC
TGGAAGCCAGCTGAGCCCCCCACTGTGGTGACTGGCAGTCTCCTAGTGAGACCAGTGAGCGACTGCTCCACCCTGCCCTGCCTGCCACTG
CCTGCGCTGTTCAACCAGGAGCCAGCCTCCGGCCAGATGCGCCTGGAGAAAACCGACCAGATTCCCATGCCTTTCTCCAGTTCCTCGTTG
AGCTGCCTGAATCTCCCTGAGGGACCCATCCAGTTTGTCCCCACCATCTCCACTCTGCCCCATGGGCTCTGGCAAATCTCTGAGGCTGGA
ACAGGGGTCTCCAGTATATTCATCTACCATGGTGAGGTGCCCCAGGCCAGCCAAGTACCCCCTCCCAGTGGATTCACTGTCCACGGCCTC
CCAACATCTCCAGACCGGCCAGGCTCCACCAGCCCCTTCGCTCCATCAGCCACTGACCTGCCCAGCATGCCTGAACCTGCCCTGACCTCC
CGAGCAAACATGACAGAGCACAAGACGTCCCCCACCCAATGCCCGGCAGCTGGAGAGGTCTCCAACAAGCTTCCAAAATGGCCTGAGCCG
GTGGAGCAGTTCTACCGCTCACTGCAGGACACGTATGGTGCCGAGCCCGCAGGCCCGGATGGCATCCTAGTGGAGGTGGATCTGGTGCAG
GCCAGGCTGGAGAGGAGCAGCAGCAAGAGCCTGGAGCGGGAACTGGCCACCCCGGACTGGGCAGAACGGCAGCTGGCCCAAGGAGGCCTG
GCTGAGGTGCTGTTGGCTGCCAAGGAGCACCGGCGGCCGCGTGAGACACGAGTGATTGCTGTGCTGGGCAAAGCTGGTCAGGGCAAGAGC
TATTGGGCTGGGGCAGTGAGCCGGGCCTGGGCTTGTGGCCGGCTTCCCCAGTACGACTTTGTCTTCTCTGTCCCCTGCCATTGCTTGAAC
CGTCCGGGGGATGCCTATGGCCTGCAGGATCTGCTCTTCTCCCTGGGCCCACAGCCACTCGTGGCGGCCGATGAGGTTTTCAGCCACATC
TTGAAGAGACCTGACCGCGTTCTGCTCATCCTAGACGGCTTCGAGGAGCTGGAAGCGCAAGATGGCTTCCTGCACAGCACGTGCGGACCG
GCACCGGCGGAGCCCTGCTCCCTCCGGGGGCTGCTGGCCGGCCTTTTCCAGAAGAAGCTGCTCCGAGGTTGCACCCTCCTCCTCACAGCC
CGGCCCCGGGGCCGCCTGGTCCAGAGCCTGAGCAAGGCCGACGCCCTATTTGAGCTGTCCGGCTTCTCCATGGAGCAGGCCCAGGCATAC
GTGATGCGCTACTTTGAGAGCTCAGGGATGACAGAGCACCAAGACAGAGCCCTGACGCTCCTCCGGGACCGGCCACTTCTTCTCAGTCAC
AGCCACAGCCCTACTTTGTGCCGGGCAGTGTGCCAGCTCTCAGAGGCCCTGCTGGAGCTTGGGGAGGACGCCAAGCTGCCCTCCACGCTC
ACGGGACTCTATGTCGGCCTGCTGGGCCGTGCAGCCCTCGACAGCCCCCCCGGGGCCCTGGCAGAGCTGGCCAAGCTGGCCTGGGAGCTG
GGCCGCAGACATCAAAGTACCCTACAGGAGGACCAGTTCCCATCCGCAGACGTGAGGACCTGGGCGATGGCCAAAGGCTTAGTCCAACAC
CCACCGCGGGCCGCAGAGTCCGAGCTGGCCTTCCCCAGCTTCCTCCTGCAATGCTTCCTGGGGGCCCTGTGGCTGGCTCTGAGTGGCGAA
ATCAAGGACAAGGAGCTCCCGCAGTACCTAGCATTGACCCCAAGGAAGAAGAGGCCCTATGACAACTGGCTGGAGGGCGTGCCACGCTTT
CTGGCTGGGCTGATCTTCCAGCCTCCCGCCCGCTGCCTGGGAGCCCTACTCGGGCCATCGGCGGCTGCCTCGGTGGACAGGAAGCAGAAG
GTGCTTGCGAGGTACCTGAAGCGGCTGCAGCCGGGGACACTGCGGGCGCGGCAGCTGCTGGAGCTGCTGCACTGCGCCCACGAGGCCGAG
GAGGCTGGAATTTGGCAGCACGTGGTACAGGAGCTCCCCGGCCGCCTCTCTTTTCTGGGCACCCGCCTCACGCCTCCTGATGCACATGTA
CTGGGCAAGGCCTTGGAGGCGGCGGGCCAAGACTTCTCCCTGGACCTCCGCAGCACTGGCATTTGCCCCTCTGGATTGGGGAGCCTCGTG
GGACTCAGCTGTGTCACCCGTTTCAGGGCTGCCTTGAGCGACACGGTGGCGCTGTGGGAGTCCCTGCAGCAGCATGGGGAGACCAAGCTA
CTTCAGGCAGCAGAGGAGAAGTTCACCATCGAGCCTTTCAAAGCCAAGTCCCTGAAGGATGTGGAAGACCTGGGAAAGCTTGTGCAGACT
CAGAGGACGAGAAGTTCCTCGGAAGACACAGCTGGGGAGCTCCCTGCTGTTCGGGACCTAAAGAAACTGGAGTTTGCGCTGGGCCCTGTC
TCAGGCCCCCAGGCTTTCCCCAAACTGGTGCGGATCCTCACGGCCTTTTCCTCCCTGCAGCATCTGGACCTGGATGCGCTGAGTGAGAAC
AAGATCGGGGACGAGGGTGTCTCGCAGCTCTCAGCCACCTTCCCCCAGCTGAAGTCCTTGGAAACCCTCAATCTGTCCCAGAACAACATC
ACTGACCTGGGTGCCTACAAACTCGCCGAGGCCCTGCCTTCGCTCGCTGCATCCCTGCTCAGGCTAAGCTTGTACAATAACTGCATCTGC
GACGTGGGAGCCGAGAGCTTGGCTCGTGTGCTTCCGGACATGGTGTCCCTCCGGGTGATGGACGTCCAGTACAACAAGTTCACGGCTGCC
GGGGCCCAGCAGCTCGCTGCCAGCCTTCGGAGGTGTCCTCATGTGGAGACGCTGGCGATGTGGACGCCCACCATCCCATTCAGTGTCCAG
GAACACCTGCAACAACAGGATTCACGGATCAGCCTGAGATGATCCCAGCTGTGCTCTGGACAGGCATGTTCTCTGAGGACACTAACCACG
CTGGACCTTGAACTGGGTACTTGTGGACACAGCTCTTCTCCAGGCTGTATCCCATGAGCCTCAGCATCCTGGCACCCGGCCCCTGCTGGT
TCAGGGTTGGCCCCTGCCCGGCTGCGGAATGAACCACATCTTGCTCTGCTGACAGACACAGGCCCGGCTCCAGGCTCCTTTAGCGCCCAG
TTGGGTGGATGCCTGGTGGCAGCTGCGGTCCACCCAGGAGCCCCGAGGCCTTCTCTGAAGGACATTGCGGACAGCCACGGCCAGGCCAGA
GGGAGTGACAGAGGCAGCCCCATTCTGCCTGCCCAGGCCCCTGCCACCCTGGGGAGAAAGTACTTCTTTTTTTTTATTTTTAGACAGAGT
CTCACTGTTGCCCAGGCTGGCGTGCAGTGGTGCGATCTGGGTTCACTGCAACCTCCGCCTCTTGGGTTCAAGCGATTCTTCTGCTTCAGC
CTCCCGAGTAGCTGGGACTACAGGCACCCACCATCATGTCTGGCTAATTTTTCATTTTTAGTAGAGACAGGGTTTTGCCATGTTGGCCAG
GCTGGTCTCAAACTCTTGACCTCAGGTGATCCACCCACCTCAGCCTCCCAAAGTGCTGGGATTACAAGCGTGAGCCACTGCACCGGGCCA
CAGAGAAAGTACTTCTCCACCCTGCTCTCCGACCAGACACCTTGACAGGGCACACCGGGCACTCAGAAGACACTGATGGGCAACCCCCAG
CCTGCTAATTCCCCAGATTGCAACAGGCTGGGCTTCAGTGGCAGCTGCTTTTGTCTATGGGACTCAATGCACTGACATTGTTGGCCAAAG
CCAAAGCTAGGCCTGGCCAGATGCACCAGCCCTTAGCAGGGAAACAGCTAATGGGACACTAATGGGGCGGTGAGAGGGGAACAGACTGGA
AGCACAGCTTCATTTCCTGTGTCTTTTTTCACTACATTATAAATGTCTCTTTAATGTCACAGGCAGGTCCAGGGTTTGAGTTCATACCCT
GTTACCATTTTGGGGTACCCACTGCTCTGGTTATCTAATATGTAACAAGCCACCCCAAATCATAGTGGCTTAAAACAACACTCACATTTA
TTCTGCTCACATATCTGTCATTTGAGCAGGGCTCAGCGGGGACAGCTCCTTCTGTCCTACTCTGTGTCAGGTGGGGCAGCTTGAGGGTTG
GGCTGGTGTCACCTGAAGACTCATTCTTCTGTACGTCTGACAGGCAATGCTGGCTGTTGGCTGGGGGCCTCAGTGCCACTACGGAATAGT
TGGCTAGGACCCCTCCATGTGGGCTAGTTGGGCTTCCTCATAGTATGGTGGCTGGGTTGGAGGGTGTCCCAAAAAGAAAGGAGGGGATAG
AGAGAGACCACTTTTCATAACCTAGCCTTAGAAGTCACACAGTATTACTTCTGCTACATATATATGTTTTAAGAGGCAGGGTCTCACTCT
GTCGCCCAGTCTGGAATGCAGTGGTATGATCACGGCTCACTGCAGCCTCAACCTCCTGGGCTAAGTGATCCTCCCACCTCAGCCTCCCGA
ATAGCTGGGACTACAGGTGTGAGTCACCAAGCCCAGTTAATCTTTAGTTTTATTTTTGTAGAGCCAGGGTCTCACTATGTTGCCCAGGCA
GGTCTTGAACTCCTGGCCTCAAGTGATTCTCCTGCCTCAGCCTCCCAAAGTGCTGGGATTACAGGTGTGAACCACCACACCCAGCCCACT
TCTGCCATATTCTGTTGGCCAGTGTGACAAGGATTGCTACTGTCCTACCCACCCTCCTTTCACCACATGTGCACATGCACGTGTGTGCAC
GTACACACACATACACACACACGCGTGCACACACCAGAGCCCACCTTGGCTCAAGTCCTCTTTTCTGAGAGGACTTTTCTTTGTGGCTTC
CTAAAATTCAGTGGAAAATTAATTGTTTGGGGATGAGAAAGGTTGAAGCACCAAAAGCTTACCAAGGGGAATGTTTGCCTCTGCCTCTGA
CACACAGCTCTGTCCTGGGAGTGAGCTGGTTTTTAGCGGAGACGGAGTCCCACCTTGGCTGCAGGGAGTCCGAAAGGGACTTGGAAGCTC
CGCTTTCTACCCAGCGAGCTGCCGGCACGACTGTTGCTTTTCACTCGGGCATAGTCTGCTCAGAAGCCCCAATTCAAGACATCTTAGCTT
ACTCCTGGTGGCAGTGGGAGCTGCCTGTTCAGCTCCAGCTCACCAGCCCCAGTGCCCACAGGATCAGTCTGATTCCCAAGCTCTGCTCCT
CTCCCCAGCAAGTGAGAGCTGGGTGTCAAGAGGGTCTGAGGAATCCAGACCCGGCTGCGTGGTTGATGATCTTTGCAGACAGGCAAGCAC
CTCCTGCCTCGAACTGGCTGCAAAGGGTATCAGGTGCTGCCATCCAGGTTCAGCTTGTAAATAGCTCAGGTGTCACCCTGCAAGGGATCC
CTGCACTTGCAGACTCTACAGAGGCCATGGGCCTCCTGTGTGTGCGCCTACAGGAGTGAGCACTAAGGTGTGCTCTGATCATCCACTGTG
CCATGTGCCAGGTTTTTGGTCTGACCCACTGCTTTTGGTCTGTGTGATGATGAAATGAGGTCAGAGCCTGCAGTTATTAACACTAACGAT
TTGTTAATGATAGCTACTGTTTATTATTTTATTTAATTTTTTTGAGACAGAGTTTTCACTCTTATTGCCCACGCTGGAGTGCAGTGGCAT
GATCTCGGCTCACTGCAACCTCTGCCTCCTGGGTTCAAGCAATTCTCCCACCTCAGCCTCCCAAGTAGCTGGGATTACAGGCATGCACCA
CCACGCCTGGCTAATTTTTGTATTTTTAGTAGAGATGGAGTTTCACCATGTTGGCCAGGCTGGTAATCTGCCTGCCTTGGCCTCCCAAAG
TGCTGGGATTACAGGGGTGAGCCACCGCACCCGGCCACTACTGTTTATTTAATGAGCAGATACATGCAAAGCCCTTATCACAGTGCAAGG
GAAATTCAAAGCGCTCAGAAAGTATTAGCTCAATAAGTGATGACTGTGTGCCAGACACTGTGCTAAACTCCTACTCAAGAGGGATAAGAG
TCTAGGGGCAAGTGGCAGAGACTCTAGAACGAGATTGCCTGGGCTCAACGCCCACCTCACCACTTACTTATGCAAGCTAGTTCTCTGTGC
CTCAGTCTCCTCATTTGTAAAATGGGCATAACCACAGCACCTTCTTTATAGGATTATGTGAAGGTGTGGTGAGCTAATACGTTAAGAATT
GGAGCTCAATAACATGTTGGCTGTCATTATTACATATATCTGTGTTTCATTCTTGCCTCTGGCTGGAATGTTCTTCCCAGCTCTCCATAT
GGCTGATTTCTCATCCTTCGGGACTTGCCCCATTCTCCAACCCCATCACTAGTTTTATCTTTTTCACTTATTTATGCAGTCTGCTCTTGT
CCTAGGACATGAGCTCCAGGAGGGCGGGAAACATCTCGCTTTGTACACTGCTGTGCCCTCTGTACCCAGCAAGGCGCCTGTGTATAATAG
GTGCTCAATAACATAAAATGAACAAATAATCCTCACCTAACGGTTTCATTCATTCTGCAAATACATACTGACAGCACAGTCATGAATAAG
ATGTTCCTGCCCTGGTGAGTCTTATATTTTAGCAAATTAAAAAAACTCTTTGGACAGGGCTGCCAGGTGAGGTTGGCCAGTCTGTACACT
GCACAAAGGCACCTGGGACAAGGGGGAACATGGGGGCTGCAAACCAGTCTGGGTTCTGCTTGCCAAACTGGGAGTCCTGGTGTGGAGCCT
TTTAACCCAGAGGGGCATCTTTTCGTAGTTAACGCACAGTCATCGTAAGATGTGGATAAATTACTGTCTCCGTGTCACAGATCTAAGTGA
TACTTATAGTCACACTCCTATAAAGGAATGGACTTCTGACTTCTTTGGAGGACCTCTCTGCAGGGACAGGCACAGTGTGCCGGAAGTGCC
CCTGAACCCCATTTGTCAGGTGGTAAAGCGCTGCTCGGAGGAATCAGGGCATGATAGTGCAATTCCATGTCCAGTGGATTGTAAGTCCAC
GCACCTTCCAAATGGTCACTCTTCCTCGCAGGCCTCTCTCTGCATACAAATGTCTCCCTCCTGACGCTCACCTTTTTCCCTGGGGCTCTC
AAATGTCTTCTTTTCAGATTTCGTAGCTTTTCTTTCTTTAGCATCACTTGAGGGCAAGTGGTGCTCCAACTGTCTCCCCCCAGAGTTCTG
CCGCCTGTACTCTCCCACACCTCAGTCTCCTCGCCTGTAGAAAGGGGTCAATCGTTTGAACCCTGCTTCACTTGGTGTGTATGTGAAGGT
GCTTTGAAATCAAGTGCTCTGCAAACTGGAGAGAATTACTGCTTGTATTCCGTGAAACTACAAGCTCCCAATTCCACTCATTTAATCCCT
CTCTTGCTCTGTTGCCCAGGCTGGAATGCAGTGGCATGATCTCAACTCACTGCAACCTCTGCCTCCCTGGTTTCAAGCAATTCTCCTGCC
TCAGCCTCCCGAGTAGCTGGGACTATAAGTGTGCGCCACTATGCCTGGCTAATTTTTTTGTATTTTTAGTAGAGATGGGGTTTCACCGTG
GTGGCCAGGCTGGTCTCGAACTCCTAACCTCAAGTGATCTGCCCGCCTCGGCCTTCCAAAGTGCTGGGATTACAGGCATGAGCCACCATG
CCAAGCCCTTCCCCCCTATCTTTAATGAAGGTCTACCATGTGCCTGACACAGGGGATACCCACCCCCACTTCTATGGGATTCAGGCCTGG
TTTCCAGCTTGGCCTTCAGGCTTTTCCCACCACACCCCAAATGCTGTCCCTGGCTTGTGGAGTGGGGCAGGGGGCCAGCCTGGGACTTTC
ACGCCAGCCCGACTGGGGCAGACTCTCTCAACCCCACTGGATCTTCTGCTGTTTGTCAGCCACAAGGTTCTGCCTAGAACTCCTTTCCCG
AATCTCAAAGTTAAAAAAAAAGGCAGGGCCCCAGGGGTTGGAGTTGCATACATTTTTTTTTAATCCAAAGAAGTAAGCCTCCTAAGTATT
GCTTAGACAGGTTTATCAGAATTAAGTAGGCACAACACTCATACTTTCAGAAAAGCATTTCCAGCCAGGGGAGTAACGTGGCACTCACCA
GCATGATGTCTGTTTTGCCAACTTGCTGAAGAACGAGTAACCTGAAATGAAGGAGCGAGAATCCCACCCTCAGCCCCCCAACAGCTTCCT
CAGCTTCTTTTTCTTCTGAGTCACCCCTGAAACAGTCGCTGCATCTAAGACCAGCCTCGGGCTAAACCCAGCTGGCCTGAAGGCTCAACT
CACATCAAACGGAGCTGGGAGTCGCTTTTGCGTGTGTCCGCAGTTTGAAGTGTCCTCTCCGAAGGTGAAGTGGGGGAAGCAGGTGCGCTC
CGGGATGAAGTGCAGGGAGGCAAACTCTGGCTGGGTTCCTGTAAACATCCATCGCAGCTGCAAATAATCAGAAGCCAAGGCCAGGCCATC
GATTTGACACTGCAGGCAGATGAGGTCTTGGGATGCCTCTTGCGTTCCCCCTTCTGTGGGAGCAGGTGCCTTCCCAACCTCAGCACTCAG
TCCCAATCTCTCTTCCACTCTCCTGGGTTCAAACAGGAACCTCTCTGTTGGCACGAAGCTTTTGAGGGGAGCAGGTCTAACAAGAAGGAA
AAAGGGGGGTTATTAGCACGGAAGCCCCACCCTGCCACCAGGTTGGCTGGGGACAGGGACCAATCCACCAGGCTCGGGAGGCTTGGGGTG
GGGCAGGGAAGTCTTCCTCCATCCCTCAAATTTAGGGAACCACTGGGAGCCCCAGACTCAGGCTGAAAATGTCTTTCTGCAAATATAAAA

>84946_84946_5_SNX29-CIITA_SNX29_chr16_12172772_ENST00000566228_CIITA_chr16_10989139_ENST00000324288_length(amino acids)=1580AA_BP=468
MSGSQNNDKRQFLLERLLDAVKQCQIRFGGRKEIASDSDSRVTCLCAQFEAVLQHGLKRSRGLALTAAAIKQAAGFASKTETEPVFWYYV
KEVLNKHELQRFYSLRHIASDVGRGRAWLRCALNEHSLERYLHMLLADRCRLSTFYEDWSFVMDEERSSMLPTMAAGLNSILFAINIDNK
DLNGQSKFAPTVSDLLKESTQNVTSLLKESTQGVSSLFREITASSAVSILIKPEQETDPLPVVSRNVSADAKCKKERKKKKKVTNIISFD
DEEDEQNSGDVFKKTPGAGESSEDNSDRSSVNIMSAFESPFGPNSNGSQSSNSWKIDSLSLNGEFGYQKLDVKSIDDEDVDENEDDVYGN
SSGRKHRGHSESPEKPLEGNTCLSQMHSWAPLKVLHNDSDILFPVSGVGSYSPADAPLGSLENGTGPEDHVLPDPGLRYSVEASSPGHGS
PLSSLLPSASVPESMTISSSQCATMELGPLEGGYLELLNSDADPLCLYHFYDQMDLAGEEEIELYSEPDTDTINCDQFSRLLCDMEGDEE
TREAYANIAELDQYVFQDSQLEGLSKDIFKHIGPDEVIGESMEMPAEVGQKSQKRPFPEELPADLKHWKPAEPPTVVTGSLLVRPVSDCS
TLPCLPLPALFNQEPASGQMRLEKTDQIPMPFSSSSLSCLNLPEGPIQFVPTISTLPHGLWQISEAGTGVSSIFIYHGEVPQASQVPPPS
GFTVHGLPTSPDRPGSTSPFAPSATDLPSMPEPALTSRANMTEHKTSPTQCPAAGEVSNKLPKWPEPVEQFYRSLQDTYGAEPAGPDGIL
VEVDLVQARLERSSSKSLERELATPDWAERQLAQGGLAEVLLAAKEHRRPRETRVIAVLGKAGQGKSYWAGAVSRAWACGRLPQYDFVFS
VPCHCLNRPGDAYGLQDLLFSLGPQPLVAADEVFSHILKRPDRVLLILDGFEELEAQDGFLHSTCGPAPAEPCSLRGLLAGLFQKKLLRG
CTLLLTARPRGRLVQSLSKADALFELSGFSMEQAQAYVMRYFESSGMTEHQDRALTLLRDRPLLLSHSHSPTLCRAVCQLSEALLELGED
AKLPSTLTGLYVGLLGRAALDSPPGALAELAKLAWELGRRHQSTLQEDQFPSADVRTWAMAKGLVQHPPRAAESELAFPSFLLQCFLGAL
WLALSGEIKDKELPQYLALTPRKKRPYDNWLEGVPRFLAGLIFQPPARCLGALLGPSAAASVDRKQKVLARYLKRLQPGTLRARQLLELL
HCAHEAEEAGIWQHVVQELPGRLSFLGTRLTPPDAHVLGKALEAAGQDFSLDLRSTGICPSGLGSLVGLSCVTRFRAALSDTVALWESLQ
QHGETKLLQAAEEKFTIEPFKAKSLKDVEDLGKLVQTQRTRSSSEDTAGELPAVRDLKKLEFALGPVSGPQAFPKLVRILTAFSSLQHLD
LDALSENKIGDEGVSQLSATFPQLKSLETLNLSQNNITDLGAYKLAEALPSLAASLLRLSLYNNCICDVGAESLARVLPDMVSLRVMDVQ

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>84946_84946_6_SNX29-CIITA_SNX29_chr16_12172772_ENST00000566228_CIITA_chr16_10989139_ENST00000381835_length(transcript)=3642nt_BP=1471nt
GGAGCTCGGCAGCCGCAGAAGCGGCAGCGGCGGCGGCGCGGCGCAGGCACCGGCCCGGGGAGAGGCACCATGAGCGGATCACAGAACAAT
GACAAAAGACAATTTCTGCTGGAGCGACTGCTGGATGCAGTGAAACAGTGCCAGATCCGCTTTGGAGGGAGAAAGGAGATTGCCTCGGAT
TCCGACAGCAGGGTCACCTGTCTGTGTGCCCAGTTTGAAGCCGTCCTGCAGCATGGCTTGAAGAGGAGTCGAGGATTGGCACTCACAGCG
GCAGCGATCAAGCAGGCAGCGGGCTTTGCCAGCAAAACCGAAACAGAGCCCGTGTTCTGGTACTACGTGAAGGAGGTCCTCAACAAGCAC
GAGCTGCAGCGCTTCTACTCCCTGCGCCACATCGCCTCAGACGTGGGCCGGGGTCGCGCCTGGCTGCGCTGTGCCCTCAACGAACACTCC
CTGGAGCGCTACCTGCACATGCTCCTGGCCGACCGCTGCAGGCTGAGCACTTTTTATGAAGACTGGTCTTTTGTGATGGATGAAGAAAGG
TCCAGTATGCTTCCTACCATGGCAGCAGGTCTGAACTCCATACTCTTTGCGATTAACATCGACAACAAGGATTTGAACGGGCAGAGTAAG
TTTGCTCCCACCGTTTCAGACCTCTTAAAGGAGTCAACGCAGAACGTGACCTCCTTGCTGAAGGAGTCCACGCAAGGAGTGAGCAGCCTG
TTCAGGGAGATCACAGCCTCCTCTGCCGTCTCCATCCTCATCAAACCTGAACAGGAGACCGACCCCTTGCCTGTCGTGTCCAGGAATGTC
AGTGCTGATGCCAAATGCAAAAAGGAGCGGAAGAAGAAAAAGAAAGTGACCAACATAATCTCATTTGATGATGAGGAAGATGAGCAGAAC
TCTGGGGACGTGTTTAAAAAGACACCTGGGGCAGGGGAGAGCTCAGAGGACAACTCCGACCGCTCCTCTGTCAATATCATGTCCGCCTTT
GAAAGCCCCTTCGGGCCTAACTCCAATGGAAGTCAGAGCAGCAACTCATGGAAAATTGATTCCCTGTCTTTGAACGGGGAGTTTGGGTAC
CAGAAGCTTGATGTGAAAAGCATCGATGATGAAGATGTGGATGAAAACGAAGATGACGTGTATGGAAACTCATCAGGAAGGAAGCACAGG
GGCCACTCGGAGTCGCCCGAGAAGCCACTGGAAGGGAACACCTGCCTCTCCCAGATGCACAGCTGGGCTCCGCTGAAGGTGCTGCACAAT
GACTCCGACATCCTCTTCCCTGTCAGTGGCGTGGGCTCCTACAGCCCAGCAGATGCCCCCCTCGGAAGCCTGGAGAACGGGACAGGACCA
GAGGACCACGTTCTCCCAGATCCTGGACTTCGGTACAGTGTGGAAGCCAGCTCTCCAGGCCACGGAAGTCCTCTGAGCAGCCTGTTACCT
TCTGCCTCAGTGCCAGAGTCCATGACAATTAGCAGCTCACAGTGTGCCACCATGGAGTTGGGGCCCCTAGAAGGTGGCTACCTGGAGCTT
CTTAACAGCGATGCTGACCCCCTGTGCCTCTACCACTTCTATGACCAGATGGACCTGGCTGGAGAAGAAGAGATTGAGCTCTACTCAGAA
CCCGACACAGACACCATCAACTGCGACCAGTTCAGCAGGCTGTTGTGTGACATGGAAGGTGATGAAGAGACCAGGGAGGCTTATGCCAAT
ATCGCGGAACTGGACCAGTATGTCTTCCAGGACTCCCAGCTGGAGGGCCTGAGCAAGGACATTTTCAAGCACATAGGACCAGATGAAGTG
ATCGGTGAGAGTATGGAGATGCCAGCAGAAGTTGGGCAGAAAAGTCAGAAAAGACCCTTCCCAGAGGAGCTTCCGGCAGACCTGAAGCAC
TGGAAGCCAGTGCCTTTCTCCAGTTCCTCGTTGAGCTGCCTGAATCTCCCTGAGGGACCCATCCAGTTTGTCCCCACCATCTCCACTCTG
CCCCATGGGCTCTGGCAAATCTCTGAGGCTGGAACAGGGGTCTCCAGTATATTCATCTACCATGGTGAGGTGCCCCAGGCCAGCCAAGTA
CCCCCTCCCAGTGGATTCACTGTCCACGGCCTCCCAACATCTCCAGACCGGCCAGGCTCCACCAGCCCCTTCGCTCCATCAGCCACTGAC
CTGCCCAGCATGCCTGAACCTGCCCTGACCTCCCGAGCAAACATGACAGAGCACAAGACGTCCCCCACCCAATGCCCGGCAGCTGGAGAG
GTCTCCAACAAGCTTCCAAAATGGCCTGGTCTAGCCTGGTCACCGTGCCTGGGTCTGAGGCCCTCCCTCCACAGGGCTGCCTTGAGCGAC
ACGGTGGCGCTGTGGGAGTCCCTGCAGCAGCATGGGGAGACCAAGCTACTTCAGGCAGCAGAGGAGAAGTTCACCATCGAGCCTTTCAAA
GCCAAGTCCCTGAAGGATGTGGAAGACCTGGGAAAGCTTGTGCAGACTCAGAGGACGAGAAGTTCCTCGGAAGACACAGCTGGGGAGCTC
CCTGCTGTTCGGGACCTAAAGAAACTGGAGTTTGCGCTGGGCCCTGTCTCAGGCCCCCAGGCTTTCCCCAAACTGGTGCGGATCCTCACG
GCCTTTTCCTCCCTGCAGCATCTGGACCTGGATGCGCTGAGTGAGAACAAGATCGGGGACGAGGGTGTCTCGCAGCTCTCAGCCACCTTC
CCCCAGCTGAAGTCCTTGGAAACCCTCAATCTGTCCCAGAACAACATCACTGACCTGGGTGCCTACAAACTCGCCGAGGCCCTGCCTTCG
CTCGCTGCATCCCTGCTCAGGCTAAGCTTGTACAATAACTGCATCTGCGACGTGGGAGCCGAGAGCTTGGCTCGTGTGCTTCCGGACATG
GTGTCCCTCCGGGTGATGGACGTCCAGTACAACAAGTTCACGGCTGCCGGGGCCCAGCAGCTCGCTGCCAGCCTTCGGAGGTGTCCTCAT
GTGGAGACGCTGGCGATGTGGACGCCCACCATCCCATTCAGTGTCCAGGAACACCTGCAACAACAGGATTCACGGATCAGCCTGAGATGA
TCCCAGCTGTGCTCTGGACAGGCATGTTCTCTGAGGACACTAACCACGCTGGACCTTGAACTGGGTACTTGTGGACACAGCTCTTCTCCA
GGCTGTATCCCATGAGCCTCAGCATCCTGGCACCCGGCCCCTGCTGGTTCAGGGTTGGCCCCTGCCCGGCTGCGGAATGAACCACATCTT
GCTCTGCTGACAGACACAGGCCCGGCTCCAGGCTCCTTTAGCGCCCAGTTGGGTGGATGCCTGGTGGCAGCTGCGGTCCACCCAGGAGCC
CCGAGGCCTTCTCTGAAGGACATTGCGGACAGCCACGGCCAGGCCAGAGGGAGTGACAGAGGCAGCCCCATTCTGCCTGCCCAGGCCCCT
GCCACCCTGGGGAGAAAGTACTTCTTTTTTTTTATTTTTAGACAGAGTCTCACTGTTGCCCAGGCTGGCGTGCAGTGGTGCGATCTGGGT
TCACTGCAACCTCCGCCTCTTGGGTTCAAGCGATTCTTCTGCTTCAGCCTCCCGAGTAGCTGGGACTACAGGCACCCACCATCATGTCTG

>84946_84946_6_SNX29-CIITA_SNX29_chr16_12172772_ENST00000566228_CIITA_chr16_10989139_ENST00000381835_length(amino acids)=996AA_BP=468
MSGSQNNDKRQFLLERLLDAVKQCQIRFGGRKEIASDSDSRVTCLCAQFEAVLQHGLKRSRGLALTAAAIKQAAGFASKTETEPVFWYYV
KEVLNKHELQRFYSLRHIASDVGRGRAWLRCALNEHSLERYLHMLLADRCRLSTFYEDWSFVMDEERSSMLPTMAAGLNSILFAINIDNK
DLNGQSKFAPTVSDLLKESTQNVTSLLKESTQGVSSLFREITASSAVSILIKPEQETDPLPVVSRNVSADAKCKKERKKKKKVTNIISFD
DEEDEQNSGDVFKKTPGAGESSEDNSDRSSVNIMSAFESPFGPNSNGSQSSNSWKIDSLSLNGEFGYQKLDVKSIDDEDVDENEDDVYGN
SSGRKHRGHSESPEKPLEGNTCLSQMHSWAPLKVLHNDSDILFPVSGVGSYSPADAPLGSLENGTGPEDHVLPDPGLRYSVEASSPGHGS
PLSSLLPSASVPESMTISSSQCATMELGPLEGGYLELLNSDADPLCLYHFYDQMDLAGEEEIELYSEPDTDTINCDQFSRLLCDMEGDEE
TREAYANIAELDQYVFQDSQLEGLSKDIFKHIGPDEVIGESMEMPAEVGQKSQKRPFPEELPADLKHWKPVPFSSSSLSCLNLPEGPIQF
VPTISTLPHGLWQISEAGTGVSSIFIYHGEVPQASQVPPPSGFTVHGLPTSPDRPGSTSPFAPSATDLPSMPEPALTSRANMTEHKTSPT
QCPAAGEVSNKLPKWPGLAWSPCLGLRPSLHRAALSDTVALWESLQQHGETKLLQAAEEKFTIEPFKAKSLKDVEDLGKLVQTQRTRSSS
EDTAGELPAVRDLKKLEFALGPVSGPQAFPKLVRILTAFSSLQHLDLDALSENKIGDEGVSQLSATFPQLKSLETLNLSQNNITDLGAYK
LAEALPSLAASLLRLSLYNNCICDVGAESLARVLPDMVSLRVMDVQYNKFTAAGAQQLAASLRRCPHVETLAMWTPTIPFSVQEHLQQQD

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Fusion Gene PPI Analysis for SNX29-CIITA


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for SNX29-CIITA


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for SNX29-CIITA


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource