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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:SOCS7-FLOT2 (FusionGDB2 ID:85096)

Fusion Gene Summary for SOCS7-FLOT2

check button Fusion gene summary
Fusion gene informationFusion gene name: SOCS7-FLOT2
Fusion gene ID: 85096
HgeneTgene
Gene symbol

SOCS7

FLOT2

Gene ID

122809

2319

Gene namesuppressor of cytokine signaling 4flotillin 2
SynonymsSOCS7ECS-1|ECS1|ESA|ESA1|M17S1
Cytomap

14q22.3

17q11.2

Type of geneprotein-codingprotein-coding
Descriptionsuppressor of cytokine signaling 4SH2 domain containing SOCS box proteinSOCS-4SOCS-7suppressor of cytokine signaling 7flotillin-2Flotillin 2 (epidermal surface antigen 1)epidermal surface antigenmembrane component chromosome 17 surface marker 1membrane component, chromosome 17, surface marker 1 (35kD protein identified by monoclonal antibody ECS-1)
Modification date2020031320200320
UniProtAcc.

Q14254

Ensembl transtripts involved in fusion geneENST00000331159, ENST00000577233, 
ENST00000577789, ENST00000394906, 
ENST00000394908, ENST00000585169, 
Fusion gene scores* DoF score11 X 7 X 7=5396 X 7 X 4=168
# samples 138
** MAII scorelog2(13/539*10)=-2.05177364972405
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(8/168*10)=-1.0703893278914
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: SOCS7 [Title/Abstract] AND FLOT2 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointSOCS7(36533668)-FLOT2(27216044), # samples:3
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneSOCS7

GO:0007175

negative regulation of epidermal growth factor-activated receptor activity

15590694


check buttonFusion gene breakpoints across SOCS7 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across FLOT2 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4BRCATCGA-A1-A0SM-01ASOCS7chr17

36533668

-FLOT2chr17

27216044

-
ChimerDB4BRCATCGA-A1-A0SM-01ASOCS7chr17

36533668

+FLOT2chr17

27216044

-


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Fusion Gene ORF analysis for SOCS7-FLOT2

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000331159ENST00000577789SOCS7chr17

36533668

+FLOT2chr17

27216044

-
5CDS-intronENST00000577233ENST00000577789SOCS7chr17

36533668

+FLOT2chr17

27216044

-
In-frameENST00000331159ENST00000394906SOCS7chr17

36533668

+FLOT2chr17

27216044

-
In-frameENST00000331159ENST00000394908SOCS7chr17

36533668

+FLOT2chr17

27216044

-
In-frameENST00000331159ENST00000585169SOCS7chr17

36533668

+FLOT2chr17

27216044

-
In-frameENST00000577233ENST00000394906SOCS7chr17

36533668

+FLOT2chr17

27216044

-
In-frameENST00000577233ENST00000394908SOCS7chr17

36533668

+FLOT2chr17

27216044

-
In-frameENST00000577233ENST00000585169SOCS7chr17

36533668

+FLOT2chr17

27216044

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000331159SOCS7chr1736533668+ENST00000394906FLOT2chr1727216044-40331404142806930
ENST00000331159SOCS7chr1736533668+ENST00000394908FLOT2chr1727216044-38681404142641875
ENST00000331159SOCS7chr1736533668+ENST00000585169FLOT2chr1727216044-38621404142641875
ENST00000577233SOCS7chr1736533668+ENST00000394906FLOT2chr1727216044-4118148902891963
ENST00000577233SOCS7chr1736533668+ENST00000394908FLOT2chr1727216044-3953148902726908
ENST00000577233SOCS7chr1736533668+ENST00000585169FLOT2chr1727216044-3947148902726908

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000331159ENST00000394906SOCS7chr1736533668+FLOT2chr1727216044-0.0059525140.9940475
ENST00000331159ENST00000394908SOCS7chr1736533668+FLOT2chr1727216044-0.0089974530.9910026
ENST00000331159ENST00000585169SOCS7chr1736533668+FLOT2chr1727216044-0.0084395840.9915604
ENST00000577233ENST00000394906SOCS7chr1736533668+FLOT2chr1727216044-0.0040695660.9959305
ENST00000577233ENST00000394908SOCS7chr1736533668+FLOT2chr1727216044-0.0062282420.99377173
ENST00000577233ENST00000585169SOCS7chr1736533668+FLOT2chr1727216044-0.0058862190.99411374

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Fusion Genomic Features for SOCS7-FLOT2


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for SOCS7-FLOT2


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr17:36533668/chr17:27216044)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
.FLOT2

Q14254

FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: May act as a scaffolding protein within caveolar membranes, functionally participating in formation of caveolae or caveolae-like vesicles. May be involved in epidermal cell adhesion and epidermal structure and function.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneSOCS7chr17:36533668chr17:27216044ENST00000577233+710141_148496404.0Compositional biasNote=Poly-Gly
HgeneSOCS7chr17:36533668chr17:27216044ENST00000577233+710180_187496404.0Compositional biasNote=Poly-Gln
HgeneSOCS7chr17:36533668chr17:27216044ENST00000577233+710188_197496404.0Compositional biasNote=Poly-Pro
HgeneSOCS7chr17:36533668chr17:27216044ENST00000577233+710303_312496404.0Compositional biasNote=Poly-Pro
HgeneSOCS7chr17:36533668chr17:27216044ENST00000577233+710343_350496404.0Compositional biasNote=Poly-Pro
HgeneSOCS7chr17:36533668chr17:27216044ENST00000577233+71082_97496404.0Compositional biasNote=Poly-Pro
HgeneSOCS7chr17:36533668chr17:27216044ENST00000577233+710400_509496404.0DomainSH2
HgeneSOCS7chr17:36533668chr17:27216044ENST00000577233+710504_554496404.0DomainSOCS box

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note


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Fusion Gene Sequence for SOCS7-FLOT2


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>85096_85096_1_SOCS7-FLOT2_SOCS7_chr17_36533668_ENST00000331159_FLOT2_chr17_27216044_ENST00000394906_length(transcript)=4033nt_BP=1404nt
CCCGGCCGCCGCAGCTGATGGTGTTCCGCAACGTGGGTCGGCCGCCGGAGGAGGAGGACGTGGAGGCGGCCCCGGAGCCGGGACCCTCGG
AACTGCTGTGTCCCCGGCACCGCTGTGCCCTGGACCCCAAGGCCCTGCCGCCGGGCTTGGCGCTCGAGCGGACCTGGGGCCCGGCGGCTG
GACTAGAGGCGCAGTTGGCGGCTCTGGGGCTCGGGCAGCCGGCGGGGCCGGGGGTCAAGACAGTCGGTGGGGGTTGCTGCCCGTGTCCGT
GTCCTCCTCAGCCGCCCCCTCCGCAGCCCCAGCCGCCTGCTGCCGCCCCGCAGGCCGGGGAGGACCCCACGGAAACGAGCGACGCGCTGC
TGGTCCTGGAGGGCTTGGAATCGGAGGCCGAGAGCCTGGAGACTAACAGCTGCTCGGAAGAGGAGCTCAGCAGCCCGGGTCGCGGAGGAG
GAGGGGGCGGCCGGCTTCTGCTGCAGCCCCCAGGCCCTGAATTACCTCCGGTGCCCTTCCCGCTGCAGGACTTGGTCCCTCTGGGGCGCC
TGAGTAGAGGGGAGCAGCAGCAGCAGCAGCAGCAGCAACCTCCCCCGCCCCCGCCTCCTCCCGGGCCCCTCCGGCCACTCGCGGGTCCTT
CTCGGAAGGGCTCCTTCAAAATCCGCCTCAGTCGCCTCTTTCGCACCAAGAGCTGCAACGGTGGCTCCGGCGGTGGGGATGGGACCGGCA
AGAGGCCTTCTGGAGAGCTGGCTGCTTCAGCTGCGAGCCTGACAGACATGGGAGGCTCTGCGGGCCGGGAGCTGGACGCGGGGAGGAAAC
CCAAGTTGACAAGAACTCAAAGTGCCTTTTCTCCGGTCTCCTTCAGCCCCCTGTTCACAGGTGAAACTGTGTCGCTTGTGGATGTGGACA
TTTCTCAGCGGGGCCTGACCTCTCCACACCCTCCAACTCCCCCTCCTCCTCCGAGAAGAAGCCTCAGCCTCCTAGATGCATTTCCCCGGA
TTGCTCCCATCCGAGCAGCTGAATCCCTGCACAGCCAACCCCCACAGCACCTCCAGTGTCCCCTCTACCGGCCTGACTCGAGCAGCTTTG
CAGCCAGCCTTCGAGAGTTGGAGAAGTGTGGTTGGTATTGGGGGCCAATGAATTGGGAAGATGCAGAGATGAAGCTGAAAGGGAAACCAG
ATGGTTCTTTCCTGGTACGAGACAGTTCTGATCCTCGTTACATCCTGAGCCTCAGTTTCCGATCACAGGGTATCACCCACCACACTAGAA
TGGAGCACTACAGAGGAACCTTCAGCCTGTGGTGTCATCCCAAGTTTGAGGACCGCTGTCAATCTGTTGTAGAGTTTATTAAGAGAGCCA
TTATGCACTCCAAGAATGGAAAGTTTCTCTATTTCTTAAGATCCAGGGTTCCAGGGGGCTGTTGTGGTTCCGACTATAAACAGTACGTGT
TTGGCGGCTGGGCCTGGGCCTGGTGGTGTATCTCCGACACTCAGAGACTGTCTCTGGAGGTTATGACCATCCTGTGTCGCTGTGAGAATA
TTGAGACGTCGGAGGGGGTTCCACTATTCGTAACAGGGGTTGCACAGGTCCCTTGCCCTTGCCTATTGGACTGCAAGTGGGGAAACAGCA
AGGGATTCTGGAAGCTCTGCCAAGTCTGCCAGATTTCCCTAGAGATTATGACGTTGCAGCCCCGCTGCGAGGACGTAGAGACGGCCGAGG
GGGTAGCTTTAACTGTGACGGGTGTCGCCCAGGTGAAGATCATGACGGAGAAGGAACTCCTGGCCGTGGCTTGTGAGCAGTTTCTGGGTA
AGAATGTGCAGGACATCAAAAACGTCGTCCTGCAGACCCTGGAGGGACATCTGCGCTCCATCCTCGGGACCCTGACAGTGGAGCAGATTT
ATCAGGACCGGGACCAGTTTGCCAAGCTGGTGCGGGAGGTGGCAGCCCCTGATGTTGGCCGCATGGGCATTGAGATCCTCAGCTTCACCA
TCAAGGACGTGTATGACAAAGTGGACTATCTGAGCTCCCTGGGCAAGACGCAGACTGCCGTGGTGCAGAGAGATGCTGACATTGGCGTGG
CCGAGGCTGAACGGGACGCAGGCATCCGGGAAGCTGAGTGCAAGAAGGAGATGCTGGATGTGAAGTTCATGGCAGACACCAAGATTGCTG
ACTCTAAGCGAGCCTTCGAGCTGCAAAAGTCAGCCTTCAGTGAGGAGGTTAACATCAAGACAGCTGAGGCCCAGTTGGCCTATGAGCTGC
AGGGGGCCCGTGAACAGCAGAAGATCCGGCAGGAAGAGATTGAGATTGAGGTTGTGCAGCGCAAGAAACAGATTGCCGTGGAGGCACAGG
AGATCCTGCGTACGGACAAGGAGCTCATCGCTACAGTGCGCCGGCCTGCCGAGGCCGAGGCCCACCGCATCCAGCAGATTGCCGAGGGTG
AAAAGGTGAAGCAGGTCCTCTTGGCACAGGCAGAGGCTGAGAAGATCCGCAAAATCGGGGAGGCGGAAGCGGCAGTCATCGAGGCGATGG
GCAAGGCAGAGGCTGAGCGGATGAAGCTCAAGGCAGAAGCCTACCAGAAATACGGGGATGCAGCCAAGATGGCCTTGGTGCTAGAGGCCC
TGCCCCAGATTGCTGCCAAAATCGCTGCCCCACTTACCAAGGTCGATGAGATTGTGGTCCTCAGTGGAGACAACAGTAAGGTCACATCAG
AAGTGAACCGACTGCTGGCCGAGCTGCCTGCCTCTGTGCATGCCCTCACAGGCGTGGACCTGTCTAAGATACCCCTGATCAAGAAGGCCA
CTGGTGTGCAGGTGTGAGGCTCCTGCAGGCCCACTCTCTTCAGCAGCCACCCGGCCCTCCCTCCAGCACCCGTTTTAATCCCACAGAACA
ACGGGAACGTTACTGACTCTGGTGCCTTATCTCGAAGGGACCAGAAGTGCTGCGTGTTCAGGCCATCTCTGGCTGTCTTCCTGTCTCTCC
TGTCTGTCCACCTCCTCCTCTTCCTCTCCTTTACCCCACTTTCACTGCCACTTTCATCAGGTTTGTGTCTCATCTCCCTGCGTGTCTTTT
CCTTTGTCTGTCTTTTTCTTTCCCCCATGCACATCATGTAGATTAAGCTGAAGATGTTTATTACAATCACTCTCTGTGGGGGGTGGCCCT
GCTGCTCCTCAGAATCCTGGTGCCTTGAAGTTCTCTGTGCATCTGTCCATCCTCCCTATGGCCCTGGCCAGAGCTCAGCATGGGCAGGGG
TTCTGGGTAGGACGGTCACTGTCCTCTCTCCTGGACTGGTCTTCCCAGCCCTAAACCCTGCCCCAGGAAGCCCACAGCCTCACCTGCTGC
TGCCCCTCTAGGTCTGGGCAGCCATGACCTGCAGGGCCCAGAGACACTGTCCTTCCCCTCATCCACCCAAGGCCCCAGCCAGCGCTCATA
CCCTGTCCTTTCTCCCTGACCCCAAGGGCACAGAGGCAAGGCCTCCTGTCTACAGCAGCTTCCTCAGTTTCCTACTGCCTTAGGAGGCCC
CTGCTTGTGCTCAGGGAAGGCCTCTTCATGGGCATGTTCCTGCTGGGGCGGTGCGGTTTGGTCCCAACTCTGCTAAGTTTTCTGAGATGA
GGGTCTAGCCCTGTTGGGGACAGAAAAGTGTGTAGACCTTCTTCCTGCTAGGGCTGCACTGTCCTGGGTGTTGGGCCCTTCTGGTGGACA
AGGCTGTGCCAACCCTGTACAGAATCGAGTGCTGTAGCCTGGCCAGACCCCAGAGCCCTTGTGCCATCTTTCTTCCTGGCCAGAGTGATG
GGGTTCCAGCCATGGGGAAGCAACCCAATCCTCTGTCTCCTTGCTCCAATGGAGGCAGAAGAGCCCAGGACCCAAGCGTCTTGGCAGGGG
TGCTGTGAATGTCCAGTGGTCCCAGCTCCCCACCCTGGCCCTGCCCCAGCCTGTGTAGCTCTTCCTGCATGTGGATGCTGCATGTCTGGT

>85096_85096_1_SOCS7-FLOT2_SOCS7_chr17_36533668_ENST00000331159_FLOT2_chr17_27216044_ENST00000394906_length(amino acids)=930AA_BP=462
MMVFRNVGRPPEEEDVEAAPEPGPSELLCPRHRCALDPKALPPGLALERTWGPAAGLEAQLAALGLGQPAGPGVKTVGGGCCPCPCPPQP
PPPQPQPPAAAPQAGEDPTETSDALLVLEGLESEAESLETNSCSEEELSSPGRGGGGGGRLLLQPPGPELPPVPFPLQDLVPLGRLSRGE
QQQQQQQQPPPPPPPPGPLRPLAGPSRKGSFKIRLSRLFRTKSCNGGSGGGDGTGKRPSGELAASAASLTDMGGSAGRELDAGRKPKLTR
TQSAFSPVSFSPLFTGETVSLVDVDISQRGLTSPHPPTPPPPPRRSLSLLDAFPRIAPIRAAESLHSQPPQHLQCPLYRPDSSSFAASLR
ELEKCGWYWGPMNWEDAEMKLKGKPDGSFLVRDSSDPRYILSLSFRSQGITHHTRMEHYRGTFSLWCHPKFEDRCQSVVEFIKRAIMHSK
NGKFLYFLRSRVPGGCCGSDYKQYVFGGWAWAWWCISDTQRLSLEVMTILCRCENIETSEGVPLFVTGVAQVPCPCLLDCKWGNSKGFWK
LCQVCQISLEIMTLQPRCEDVETAEGVALTVTGVAQVKIMTEKELLAVACEQFLGKNVQDIKNVVLQTLEGHLRSILGTLTVEQIYQDRD
QFAKLVREVAAPDVGRMGIEILSFTIKDVYDKVDYLSSLGKTQTAVVQRDADIGVAEAERDAGIREAECKKEMLDVKFMADTKIADSKRA
FELQKSAFSEEVNIKTAEAQLAYELQGAREQQKIRQEEIEIEVVQRKKQIAVEAQEILRTDKELIATVRRPAEAEAHRIQQIAEGEKVKQ
VLLAQAEAEKIRKIGEAEAAVIEAMGKAEAERMKLKAEAYQKYGDAAKMALVLEALPQIAAKIAAPLTKVDEIVVLSGDNSKVTSEVNRL

--------------------------------------------------------------
>85096_85096_2_SOCS7-FLOT2_SOCS7_chr17_36533668_ENST00000331159_FLOT2_chr17_27216044_ENST00000394908_length(transcript)=3868nt_BP=1404nt
CCCGGCCGCCGCAGCTGATGGTGTTCCGCAACGTGGGTCGGCCGCCGGAGGAGGAGGACGTGGAGGCGGCCCCGGAGCCGGGACCCTCGG
AACTGCTGTGTCCCCGGCACCGCTGTGCCCTGGACCCCAAGGCCCTGCCGCCGGGCTTGGCGCTCGAGCGGACCTGGGGCCCGGCGGCTG
GACTAGAGGCGCAGTTGGCGGCTCTGGGGCTCGGGCAGCCGGCGGGGCCGGGGGTCAAGACAGTCGGTGGGGGTTGCTGCCCGTGTCCGT
GTCCTCCTCAGCCGCCCCCTCCGCAGCCCCAGCCGCCTGCTGCCGCCCCGCAGGCCGGGGAGGACCCCACGGAAACGAGCGACGCGCTGC
TGGTCCTGGAGGGCTTGGAATCGGAGGCCGAGAGCCTGGAGACTAACAGCTGCTCGGAAGAGGAGCTCAGCAGCCCGGGTCGCGGAGGAG
GAGGGGGCGGCCGGCTTCTGCTGCAGCCCCCAGGCCCTGAATTACCTCCGGTGCCCTTCCCGCTGCAGGACTTGGTCCCTCTGGGGCGCC
TGAGTAGAGGGGAGCAGCAGCAGCAGCAGCAGCAGCAACCTCCCCCGCCCCCGCCTCCTCCCGGGCCCCTCCGGCCACTCGCGGGTCCTT
CTCGGAAGGGCTCCTTCAAAATCCGCCTCAGTCGCCTCTTTCGCACCAAGAGCTGCAACGGTGGCTCCGGCGGTGGGGATGGGACCGGCA
AGAGGCCTTCTGGAGAGCTGGCTGCTTCAGCTGCGAGCCTGACAGACATGGGAGGCTCTGCGGGCCGGGAGCTGGACGCGGGGAGGAAAC
CCAAGTTGACAAGAACTCAAAGTGCCTTTTCTCCGGTCTCCTTCAGCCCCCTGTTCACAGGTGAAACTGTGTCGCTTGTGGATGTGGACA
TTTCTCAGCGGGGCCTGACCTCTCCACACCCTCCAACTCCCCCTCCTCCTCCGAGAAGAAGCCTCAGCCTCCTAGATGCATTTCCCCGGA
TTGCTCCCATCCGAGCAGCTGAATCCCTGCACAGCCAACCCCCACAGCACCTCCAGTGTCCCCTCTACCGGCCTGACTCGAGCAGCTTTG
CAGCCAGCCTTCGAGAGTTGGAGAAGTGTGGTTGGTATTGGGGGCCAATGAATTGGGAAGATGCAGAGATGAAGCTGAAAGGGAAACCAG
ATGGTTCTTTCCTGGTACGAGACAGTTCTGATCCTCGTTACATCCTGAGCCTCAGTTTCCGATCACAGGGTATCACCCACCACACTAGAA
TGGAGCACTACAGAGGAACCTTCAGCCTGTGGTGTCATCCCAAGTTTGAGGACCGCTGTCAATCTGTTGTAGAGTTTATTAAGAGAGCCA
TTATGCACTCCAAGAATGGAAAGTTTCTCTATTTCTTAAGATCCAGGGTTCCAGGGGGCTGTTGTGGTTCCGACTATAAACAGTACGTGT
TTGGCGGCTGGGCCTGGGCCTGGTGGTGTATCTCCGACACTCAGAGGATTTCCCTAGAGATTATGACGTTGCAGCCCCGCTGCGAGGACG
TAGAGACGGCCGAGGGGGTAGCTTTAACTGTGACGGGTGTCGCCCAGGTGAAGATCATGACGGAGAAGGAACTCCTGGCCGTGGCTTGTG
AGCAGTTTCTGGGTAAGAATGTGCAGGACATCAAAAACGTCGTCCTGCAGACCCTGGAGGGACATCTGCGCTCCATCCTCGGGACCCTGA
CAGTGGAGCAGATTTATCAGGACCGGGACCAGTTTGCCAAGCTGGTGCGGGAGGTGGCAGCCCCTGATGTTGGCCGCATGGGCATTGAGA
TCCTCAGCTTCACCATCAAGGACGTGTATGACAAAGTGGACTATCTGAGCTCCCTGGGCAAGACGCAGACTGCCGTGGTGCAGAGAGATG
CTGACATTGGCGTGGCCGAGGCTGAACGGGACGCAGGCATCCGGGAAGCTGAGTGCAAGAAGGAGATGCTGGATGTGAAGTTCATGGCAG
ACACCAAGATTGCTGACTCTAAGCGAGCCTTCGAGCTGCAAAAGTCAGCCTTCAGTGAGGAGGTTAACATCAAGACAGCTGAGGCCCAGT
TGGCCTATGAGCTGCAGGGGGCCCGTGAACAGCAGAAGATCCGGCAGGAAGAGATTGAGATTGAGGTTGTGCAGCGCAAGAAACAGATTG
CCGTGGAGGCACAGGAGATCCTGCGTACGGACAAGGAGCTCATCGCTACAGTGCGCCGGCCTGCCGAGGCCGAGGCCCACCGCATCCAGC
AGATTGCCGAGGGTGAAAAGGTGAAGCAGGTCCTCTTGGCACAGGCAGAGGCTGAGAAGATCCGCAAAATCGGGGAGGCGGAAGCGGCAG
TCATCGAGGCGATGGGCAAGGCAGAGGCTGAGCGGATGAAGCTCAAGGCAGAAGCCTACCAGAAATACGGGGATGCAGCCAAGATGGCCT
TGGTGCTAGAGGCCCTGCCCCAGATTGCTGCCAAAATCGCTGCCCCACTTACCAAGGTCGATGAGATTGTGGTCCTCAGTGGAGACAACA
GTAAGGTCACATCAGAAGTGAACCGACTGCTGGCCGAGCTGCCTGCCTCTGTGCATGCCCTCACAGGCGTGGACCTGTCTAAGATACCCC
TGATCAAGAAGGCCACTGGTGTGCAGGTGTGAGGCTCCTGCAGGCCCACTCTCTTCAGCAGCCACCCGGCCCTCCCTCCAGCACCCGTTT
TAATCCCACAGAACAACGGGAACGTTACTGACTCTGGTGCCTTATCTCGAAGGGACCAGAAGTGCTGCGTGTTCAGGCCATCTCTGGCTG
TCTTCCTGTCTCTCCTGTCTGTCCACCTCCTCCTCTTCCTCTCCTTTACCCCACTTTCACTGCCACTTTCATCAGGTTTGTGTCTCATCT
CCCTGCGTGTCTTTTCCTTTGTCTGTCTTTTTCTTTCCCCCATGCACATCATGTAGATTAAGCTGAAGATGTTTATTACAATCACTCTCT
GTGGGGGGTGGCCCTGCTGCTCCTCAGAATCCTGGTGCCTTGAAGTTCTCTGTGCATCTGTCCATCCTCCCTATGGCCCTGGCCAGAGCT
CAGCATGGGCAGGGGTTCTGGGTAGGACGGTCACTGTCCTCTCTCCTGGACTGGTCTTCCCAGCCCTAAACCCTGCCCCAGGAAGCCCAC
AGCCTCACCTGCTGCTGCCCCTCTAGGTCTGGGCAGCCATGACCTGCAGGGCCCAGAGACACTGTCCTTCCCCTCATCCACCCAAGGCCC
CAGCCAGCGCTCATACCCTGTCCTTTCTCCCTGACCCCAAGGGCACAGAGGCAAGGCCTCCTGTCTACAGCAGCTTCCTCAGTTTCCTAC
TGCCTTAGGAGGCCCCTGCTTGTGCTCAGGGAAGGCCTCTTCATGGGCATGTTCCTGCTGGGGCGGTGCGGTTTGGTCCCAACTCTGCTA
AGTTTTCTGAGATGAGGGTCTAGCCCTGTTGGGGACAGAAAAGTGTGTAGACCTTCTTCCTGCTAGGGCTGCACTGTCCTGGGTGTTGGG
CCCTTCTGGTGGACAAGGCTGTGCCAACCCTGTACAGAATCGAGTGCTGTAGCCTGGCCAGACCCCAGAGCCCTTGTGCCATCTTTCTTC
CTGGCCAGAGTGATGGGGTTCCAGCCATGGGGAAGCAACCCAATCCTCTGTCTCCTTGCTCCAATGGAGGCAGAAGAGCCCAGGACCCAA
GCGTCTTGGCAGGGGTGCTGTGAATGTCCAGTGGTCCCAGCTCCCCACCCTGGCCCTGCCCCAGCCTGTGTAGCTCTTCCTGCATGTGGA

>85096_85096_2_SOCS7-FLOT2_SOCS7_chr17_36533668_ENST00000331159_FLOT2_chr17_27216044_ENST00000394908_length(amino acids)=875AA_BP=462
MMVFRNVGRPPEEEDVEAAPEPGPSELLCPRHRCALDPKALPPGLALERTWGPAAGLEAQLAALGLGQPAGPGVKTVGGGCCPCPCPPQP
PPPQPQPPAAAPQAGEDPTETSDALLVLEGLESEAESLETNSCSEEELSSPGRGGGGGGRLLLQPPGPELPPVPFPLQDLVPLGRLSRGE
QQQQQQQQPPPPPPPPGPLRPLAGPSRKGSFKIRLSRLFRTKSCNGGSGGGDGTGKRPSGELAASAASLTDMGGSAGRELDAGRKPKLTR
TQSAFSPVSFSPLFTGETVSLVDVDISQRGLTSPHPPTPPPPPRRSLSLLDAFPRIAPIRAAESLHSQPPQHLQCPLYRPDSSSFAASLR
ELEKCGWYWGPMNWEDAEMKLKGKPDGSFLVRDSSDPRYILSLSFRSQGITHHTRMEHYRGTFSLWCHPKFEDRCQSVVEFIKRAIMHSK
NGKFLYFLRSRVPGGCCGSDYKQYVFGGWAWAWWCISDTQRISLEIMTLQPRCEDVETAEGVALTVTGVAQVKIMTEKELLAVACEQFLG
KNVQDIKNVVLQTLEGHLRSILGTLTVEQIYQDRDQFAKLVREVAAPDVGRMGIEILSFTIKDVYDKVDYLSSLGKTQTAVVQRDADIGV
AEAERDAGIREAECKKEMLDVKFMADTKIADSKRAFELQKSAFSEEVNIKTAEAQLAYELQGAREQQKIRQEEIEIEVVQRKKQIAVEAQ
EILRTDKELIATVRRPAEAEAHRIQQIAEGEKVKQVLLAQAEAEKIRKIGEAEAAVIEAMGKAEAERMKLKAEAYQKYGDAAKMALVLEA

--------------------------------------------------------------
>85096_85096_3_SOCS7-FLOT2_SOCS7_chr17_36533668_ENST00000331159_FLOT2_chr17_27216044_ENST00000585169_length(transcript)=3862nt_BP=1404nt
CCCGGCCGCCGCAGCTGATGGTGTTCCGCAACGTGGGTCGGCCGCCGGAGGAGGAGGACGTGGAGGCGGCCCCGGAGCCGGGACCCTCGG
AACTGCTGTGTCCCCGGCACCGCTGTGCCCTGGACCCCAAGGCCCTGCCGCCGGGCTTGGCGCTCGAGCGGACCTGGGGCCCGGCGGCTG
GACTAGAGGCGCAGTTGGCGGCTCTGGGGCTCGGGCAGCCGGCGGGGCCGGGGGTCAAGACAGTCGGTGGGGGTTGCTGCCCGTGTCCGT
GTCCTCCTCAGCCGCCCCCTCCGCAGCCCCAGCCGCCTGCTGCCGCCCCGCAGGCCGGGGAGGACCCCACGGAAACGAGCGACGCGCTGC
TGGTCCTGGAGGGCTTGGAATCGGAGGCCGAGAGCCTGGAGACTAACAGCTGCTCGGAAGAGGAGCTCAGCAGCCCGGGTCGCGGAGGAG
GAGGGGGCGGCCGGCTTCTGCTGCAGCCCCCAGGCCCTGAATTACCTCCGGTGCCCTTCCCGCTGCAGGACTTGGTCCCTCTGGGGCGCC
TGAGTAGAGGGGAGCAGCAGCAGCAGCAGCAGCAGCAACCTCCCCCGCCCCCGCCTCCTCCCGGGCCCCTCCGGCCACTCGCGGGTCCTT
CTCGGAAGGGCTCCTTCAAAATCCGCCTCAGTCGCCTCTTTCGCACCAAGAGCTGCAACGGTGGCTCCGGCGGTGGGGATGGGACCGGCA
AGAGGCCTTCTGGAGAGCTGGCTGCTTCAGCTGCGAGCCTGACAGACATGGGAGGCTCTGCGGGCCGGGAGCTGGACGCGGGGAGGAAAC
CCAAGTTGACAAGAACTCAAAGTGCCTTTTCTCCGGTCTCCTTCAGCCCCCTGTTCACAGGTGAAACTGTGTCGCTTGTGGATGTGGACA
TTTCTCAGCGGGGCCTGACCTCTCCACACCCTCCAACTCCCCCTCCTCCTCCGAGAAGAAGCCTCAGCCTCCTAGATGCATTTCCCCGGA
TTGCTCCCATCCGAGCAGCTGAATCCCTGCACAGCCAACCCCCACAGCACCTCCAGTGTCCCCTCTACCGGCCTGACTCGAGCAGCTTTG
CAGCCAGCCTTCGAGAGTTGGAGAAGTGTGGTTGGTATTGGGGGCCAATGAATTGGGAAGATGCAGAGATGAAGCTGAAAGGGAAACCAG
ATGGTTCTTTCCTGGTACGAGACAGTTCTGATCCTCGTTACATCCTGAGCCTCAGTTTCCGATCACAGGGTATCACCCACCACACTAGAA
TGGAGCACTACAGAGGAACCTTCAGCCTGTGGTGTCATCCCAAGTTTGAGGACCGCTGTCAATCTGTTGTAGAGTTTATTAAGAGAGCCA
TTATGCACTCCAAGAATGGAAAGTTTCTCTATTTCTTAAGATCCAGGGTTCCAGGGGGCTGTTGTGGTTCCGACTATAAACAGTACGTGT
TTGGCGGCTGGGCCTGGGCCTGGTGGTGTATCTCCGACACTCAGAGACTGTCTCTGGAGGTTATGACCATCCTGTGTCGCTGTGAGAATA
TTGAGACGTCGGAGGGGGTTCCACTATTCGTAACAGGGGTTGCACAGGTGAAGATCATGACGGAGAAGGAACTCCTGGCCGTGGCTTGTG
AGCAGTTTCTGGGTAAGAATGTGCAGGACATCAAAAACGTCGTCCTGCAGACCCTGGAGGGACATCTGCGCTCCATCCTCGGGACCCTGA
CAGTGGAGCAGATTTATCAGGACCGGGACCAGTTTGCCAAGCTGGTGCGGGAGGTGGCAGCCCCTGATGTTGGCCGCATGGGCATTGAGA
TCCTCAGCTTCACCATCAAGGACGTGTATGACAAAGTGGACTATCTGAGCTCCCTGGGCAAGACGCAGACTGCCGTGGTGCAGAGAGATG
CTGACATTGGCGTGGCCGAGGCTGAACGGGACGCAGGCATCCGGGAAGCTGAGTGCAAGAAGGAGATGCTGGATGTGAAGTTCATGGCAG
ACACCAAGATTGCTGACTCTAAGCGAGCCTTCGAGCTGCAAAAGTCAGCCTTCAGTGAGGAGGTTAACATCAAGACAGCTGAGGCCCAGT
TGGCCTATGAGCTGCAGGGGGCCCGTGAACAGCAGAAGATCCGGCAGGAAGAGATTGAGATTGAGGTTGTGCAGCGCAAGAAACAGATTG
CCGTGGAGGCACAGGAGATCCTGCGTACGGACAAGGAGCTCATCGCTACAGTGCGCCGGCCTGCCGAGGCCGAGGCCCACCGCATCCAGC
AGATTGCCGAGGGTGAAAAGGTGAAGCAGGTCCTCTTGGCACAGGCAGAGGCTGAGAAGATCCGCAAAATCGGGGAGGCGGAAGCGGCAG
TCATCGAGGCGATGGGCAAGGCAGAGGCTGAGCGGATGAAGCTCAAGGCAGAAGCCTACCAGAAATACGGGGATGCAGCCAAGATGGCCT
TGGTGCTAGAGGCCCTGCCCCAGATTGCTGCCAAAATCGCTGCCCCACTTACCAAGGTCGATGAGATTGTGGTCCTCAGTGGAGACAACA
GTAAGGTCACATCAGAAGTGAACCGACTGCTGGCCGAGCTGCCTGCCTCTGTGCATGCCCTCACAGGCGTGGACCTGTCTAAGATACCCC
TGATCAAGAAGGCCACTGGTGTGCAGGTGTGAGGCTCCTGCAGGCCCACTCTCTTCAGCAGCCACCCGGCCCTCCCTCCAGCACCCGTTT
TAATCCCACAGAACAACGGGAACGTTACTGACTCTGGTGCCTTATCTCGAAGGGACCAGAAGTGCTGCGTGTTCAGGCCATCTCTGGCTG
TCTTCCTGTCTCTCCTGTCTGTCCACCTCCTCCTCTTCCTCTCCTTTACCCCACTTTCACTGCCACTTTCATCAGGTTTGTGTCTCATCT
CCCTGCGTGTCTTTTCCTTTGTCTGTCTTTTTCTTTCCCCCATGCACATCATGTAGATTAAGCTGAAGATGTTTATTACAATCACTCTCT
GTGGGGGGTGGCCCTGCTGCTCCTCAGAATCCTGGTGCCTTGAAGTTCTCTGTGCATCTGTCCATCCTCCCTATGGCCCTGGCCAGAGCT
CAGCATGGGCAGGGGTTCTGGGTAGGACGGTCACTGTCCTCTCTCCTGGACTGGTCTTCCCAGCCCTAAACCCTGCCCCAGGAAGCCCAC
AGCCTCACCTGCTGCTGCCCCTCTAGGTCTGGGCAGCCATGACCTGCAGGGCCCAGAGACACTGTCCTTCCCCTCATCCACCCAAGGCCC
CAGCCAGCGCTCATACCCTGTCCTTTCTCCCTGACCCCAAGGGCACAGAGGCAAGGCCTCCTGTCTACAGCAGCTTCCTCAGTTTCCTAC
TGCCTTAGGAGGCCCCTGCTTGTGCTCAGGGAAGGCCTCTTCATGGGCATGTTCCTGCTGGGGCGGTGCGGTTTGGTCCCAACTCTGCTA
AGTTTTCTGAGATGAGGGTCTAGCCCTGTTGGGGACAGAAAAGTGTGTAGACCTTCTTCCTGCTAGGGCTGCACTGTCCTGGGTGTTGGG
CCCTTCTGGTGGACAAGGCTGTGCCAACCCTGTACAGAATCGAGTGCTGTAGCCTGGCCAGACCCCAGAGCCCTTGTGCCATCTTTCTTC
CTGGCCAGAGTGATGGGGTTCCAGCCATGGGGAAGCAACCCAATCCTCTGTCTCCTTGCTCCAATGGAGGCAGAAGAGCCCAGGACCCAA
GCGTCTTGGCAGGGGTGCTGTGAATGTCCAGTGGTCCCAGCTCCCCACCCTGGCCCTGCCCCAGCCTGTGTAGCTCTTCCTGCATGTGGA

>85096_85096_3_SOCS7-FLOT2_SOCS7_chr17_36533668_ENST00000331159_FLOT2_chr17_27216044_ENST00000585169_length(amino acids)=875AA_BP=462
MMVFRNVGRPPEEEDVEAAPEPGPSELLCPRHRCALDPKALPPGLALERTWGPAAGLEAQLAALGLGQPAGPGVKTVGGGCCPCPCPPQP
PPPQPQPPAAAPQAGEDPTETSDALLVLEGLESEAESLETNSCSEEELSSPGRGGGGGGRLLLQPPGPELPPVPFPLQDLVPLGRLSRGE
QQQQQQQQPPPPPPPPGPLRPLAGPSRKGSFKIRLSRLFRTKSCNGGSGGGDGTGKRPSGELAASAASLTDMGGSAGRELDAGRKPKLTR
TQSAFSPVSFSPLFTGETVSLVDVDISQRGLTSPHPPTPPPPPRRSLSLLDAFPRIAPIRAAESLHSQPPQHLQCPLYRPDSSSFAASLR
ELEKCGWYWGPMNWEDAEMKLKGKPDGSFLVRDSSDPRYILSLSFRSQGITHHTRMEHYRGTFSLWCHPKFEDRCQSVVEFIKRAIMHSK
NGKFLYFLRSRVPGGCCGSDYKQYVFGGWAWAWWCISDTQRLSLEVMTILCRCENIETSEGVPLFVTGVAQVKIMTEKELLAVACEQFLG
KNVQDIKNVVLQTLEGHLRSILGTLTVEQIYQDRDQFAKLVREVAAPDVGRMGIEILSFTIKDVYDKVDYLSSLGKTQTAVVQRDADIGV
AEAERDAGIREAECKKEMLDVKFMADTKIADSKRAFELQKSAFSEEVNIKTAEAQLAYELQGAREQQKIRQEEIEIEVVQRKKQIAVEAQ
EILRTDKELIATVRRPAEAEAHRIQQIAEGEKVKQVLLAQAEAEKIRKIGEAEAAVIEAMGKAEAERMKLKAEAYQKYGDAAKMALVLEA

--------------------------------------------------------------
>85096_85096_4_SOCS7-FLOT2_SOCS7_chr17_36533668_ENST00000577233_FLOT2_chr17_27216044_ENST00000394906_length(transcript)=4118nt_BP=1489nt
ATGGTGTTCCGCAACGTGGGTCGGCCGCCGGAGGAGGAGGACGTGGAGGCGGCCCCGGAGCCGGGACCCTCGGAACTGCTGTGTCCCCGG
CACCGCTGTGCCCTGGACCCCAAGGCCCTGCCGCCGGGCTTGGCGCTCGAGCGGACCTGGGGCCCGGCGGCTGGACTAGAGGCGCAGTTG
GCGGCTCTGGGGCTCGGGCAGCCGGCGGGGCCGGGGGTCAAGACAGTCGGTGGGGGTTGCTGCCCGTGTCCGTGTCCTCCTCAGCCGCCC
CCTCCGCAGCCCCAGCCGCCTGCTGCCGCCCCGCAGGCCGGGGAGGACCCCACGGAAACGAGCGACGCGCTGCTGGTCCTGGAGGGCTTG
GAATCGGAGGCCGAGAGCCTGGAGACTAACAGCTGCTCGGAAGAGGAGCTCAGCAGCCCGGGTCGCGGAGGAGGAGGGGGCGGCCGGCTT
CTGCTGCAGCCCCCAGGCCCTGAATTACCTCCGGTGCCCTTCCCGCTGCAGGACTTGGTCCCTCTGGGGCGCCTGAGTAGAGGGGAGCAG
CAGCAGCAGCAGCAGCAGCAACCTCCCCCGCCCCCGCCTCCTCCCGGGCCCCTCCGGCCACTCGCGGGTCCTTCTCGGAAGGGCTCCTTC
AAAATCCGCCTCAGTCGCCTCTTTCGCACCAAGAGCTGCAACGGTGGCTCCGGCGGTGGGGATGGGACCGGCAAGAGGCCTTCTGGAGAG
CTGGCTGCTTCAGCTGCGAGCCTGACAGACATGGGAGGCTCTGCGGGCCGGGAGCTGGACGCGGGGAGGAAACCCAAGTTGACAAGAACT
CAAAGTGCCTTTTCTCCGGTCTCCTTCAGCCCCCTGTTCACAGGTGAAACTGTGTCGCTTGTGGATGTGGACATTTCTCAGCGGGGCCTG
ACCTCTCCACACCCTCCAACTCCCCCTCCTCCTCCGAGAAGAAGCCTCAGCCTCCTAGATGATATCAGTGGGACGCTGCCTACATCTGTC
CTTGTGGCTCCGATGGGGTCTTCCTTGCAGTCTTTCCCCCTACCTCCGCCTCCTCCACCCCATGCCCCAGATGCATTTCCCCGGATTGCT
CCCATCCGAGCAGCTGAATCCCTGCACAGCCAACCCCCACAGCACCTCCAGTGTCCCCTCTACCGGCCTGACTCGAGCAGCTTTGCAGCC
AGCCTTCGAGAGTTGGAGAAGTGTGGTTGGTATTGGGGGCCAATGAATTGGGAAGATGCAGAGATGAAGCTGAAAGGGAAACCAGATGGT
TCTTTCCTGGTACGAGACAGTTCTGATCCTCGTTACATCCTGAGCCTCAGTTTCCGATCACAGGGTATCACCCACCACACTAGAATGGAG
CACTACAGAGGAACCTTCAGCCTGTGGTGTCATCCCAAGTTTGAGGACCGCTGTCAATCTGTTGTAGAGTTTATTAAGAGAGCCATTATG
CACTCCAAGAATGGAAAGTTTCTCTATTTCTTAAGATCCAGGGTTCCAGGGGGCTGTTGTGGTTCCGACTATAAACAGTACGTGTTTGGC
GGCTGGGCCTGGGCCTGGTGGTGTATCTCCGACACTCAGAGACTGTCTCTGGAGGTTATGACCATCCTGTGTCGCTGTGAGAATATTGAG
ACGTCGGAGGGGGTTCCACTATTCGTAACAGGGGTTGCACAGGTCCCTTGCCCTTGCCTATTGGACTGCAAGTGGGGAAACAGCAAGGGA
TTCTGGAAGCTCTGCCAAGTCTGCCAGATTTCCCTAGAGATTATGACGTTGCAGCCCCGCTGCGAGGACGTAGAGACGGCCGAGGGGGTA
GCTTTAACTGTGACGGGTGTCGCCCAGGTGAAGATCATGACGGAGAAGGAACTCCTGGCCGTGGCTTGTGAGCAGTTTCTGGGTAAGAAT
GTGCAGGACATCAAAAACGTCGTCCTGCAGACCCTGGAGGGACATCTGCGCTCCATCCTCGGGACCCTGACAGTGGAGCAGATTTATCAG
GACCGGGACCAGTTTGCCAAGCTGGTGCGGGAGGTGGCAGCCCCTGATGTTGGCCGCATGGGCATTGAGATCCTCAGCTTCACCATCAAG
GACGTGTATGACAAAGTGGACTATCTGAGCTCCCTGGGCAAGACGCAGACTGCCGTGGTGCAGAGAGATGCTGACATTGGCGTGGCCGAG
GCTGAACGGGACGCAGGCATCCGGGAAGCTGAGTGCAAGAAGGAGATGCTGGATGTGAAGTTCATGGCAGACACCAAGATTGCTGACTCT
AAGCGAGCCTTCGAGCTGCAAAAGTCAGCCTTCAGTGAGGAGGTTAACATCAAGACAGCTGAGGCCCAGTTGGCCTATGAGCTGCAGGGG
GCCCGTGAACAGCAGAAGATCCGGCAGGAAGAGATTGAGATTGAGGTTGTGCAGCGCAAGAAACAGATTGCCGTGGAGGCACAGGAGATC
CTGCGTACGGACAAGGAGCTCATCGCTACAGTGCGCCGGCCTGCCGAGGCCGAGGCCCACCGCATCCAGCAGATTGCCGAGGGTGAAAAG
GTGAAGCAGGTCCTCTTGGCACAGGCAGAGGCTGAGAAGATCCGCAAAATCGGGGAGGCGGAAGCGGCAGTCATCGAGGCGATGGGCAAG
GCAGAGGCTGAGCGGATGAAGCTCAAGGCAGAAGCCTACCAGAAATACGGGGATGCAGCCAAGATGGCCTTGGTGCTAGAGGCCCTGCCC
CAGATTGCTGCCAAAATCGCTGCCCCACTTACCAAGGTCGATGAGATTGTGGTCCTCAGTGGAGACAACAGTAAGGTCACATCAGAAGTG
AACCGACTGCTGGCCGAGCTGCCTGCCTCTGTGCATGCCCTCACAGGCGTGGACCTGTCTAAGATACCCCTGATCAAGAAGGCCACTGGT
GTGCAGGTGTGAGGCTCCTGCAGGCCCACTCTCTTCAGCAGCCACCCGGCCCTCCCTCCAGCACCCGTTTTAATCCCACAGAACAACGGG
AACGTTACTGACTCTGGTGCCTTATCTCGAAGGGACCAGAAGTGCTGCGTGTTCAGGCCATCTCTGGCTGTCTTCCTGTCTCTCCTGTCT
GTCCACCTCCTCCTCTTCCTCTCCTTTACCCCACTTTCACTGCCACTTTCATCAGGTTTGTGTCTCATCTCCCTGCGTGTCTTTTCCTTT
GTCTGTCTTTTTCTTTCCCCCATGCACATCATGTAGATTAAGCTGAAGATGTTTATTACAATCACTCTCTGTGGGGGGTGGCCCTGCTGC
TCCTCAGAATCCTGGTGCCTTGAAGTTCTCTGTGCATCTGTCCATCCTCCCTATGGCCCTGGCCAGAGCTCAGCATGGGCAGGGGTTCTG
GGTAGGACGGTCACTGTCCTCTCTCCTGGACTGGTCTTCCCAGCCCTAAACCCTGCCCCAGGAAGCCCACAGCCTCACCTGCTGCTGCCC
CTCTAGGTCTGGGCAGCCATGACCTGCAGGGCCCAGAGACACTGTCCTTCCCCTCATCCACCCAAGGCCCCAGCCAGCGCTCATACCCTG
TCCTTTCTCCCTGACCCCAAGGGCACAGAGGCAAGGCCTCCTGTCTACAGCAGCTTCCTCAGTTTCCTACTGCCTTAGGAGGCCCCTGCT
TGTGCTCAGGGAAGGCCTCTTCATGGGCATGTTCCTGCTGGGGCGGTGCGGTTTGGTCCCAACTCTGCTAAGTTTTCTGAGATGAGGGTC
TAGCCCTGTTGGGGACAGAAAAGTGTGTAGACCTTCTTCCTGCTAGGGCTGCACTGTCCTGGGTGTTGGGCCCTTCTGGTGGACAAGGCT
GTGCCAACCCTGTACAGAATCGAGTGCTGTAGCCTGGCCAGACCCCAGAGCCCTTGTGCCATCTTTCTTCCTGGCCAGAGTGATGGGGTT
CCAGCCATGGGGAAGCAACCCAATCCTCTGTCTCCTTGCTCCAATGGAGGCAGAAGAGCCCAGGACCCAAGCGTCTTGGCAGGGGTGCTG
TGAATGTCCAGTGGTCCCAGCTCCCCACCCTGGCCCTGCCCCAGCCTGTGTAGCTCTTCCTGCATGTGGATGCTGCATGTCTGGTCTGGG

>85096_85096_4_SOCS7-FLOT2_SOCS7_chr17_36533668_ENST00000577233_FLOT2_chr17_27216044_ENST00000394906_length(amino acids)=963AA_BP=495
MVFRNVGRPPEEEDVEAAPEPGPSELLCPRHRCALDPKALPPGLALERTWGPAAGLEAQLAALGLGQPAGPGVKTVGGGCCPCPCPPQPP
PPQPQPPAAAPQAGEDPTETSDALLVLEGLESEAESLETNSCSEEELSSPGRGGGGGGRLLLQPPGPELPPVPFPLQDLVPLGRLSRGEQ
QQQQQQQPPPPPPPPGPLRPLAGPSRKGSFKIRLSRLFRTKSCNGGSGGGDGTGKRPSGELAASAASLTDMGGSAGRELDAGRKPKLTRT
QSAFSPVSFSPLFTGETVSLVDVDISQRGLTSPHPPTPPPPPRRSLSLLDDISGTLPTSVLVAPMGSSLQSFPLPPPPPPHAPDAFPRIA
PIRAAESLHSQPPQHLQCPLYRPDSSSFAASLRELEKCGWYWGPMNWEDAEMKLKGKPDGSFLVRDSSDPRYILSLSFRSQGITHHTRME
HYRGTFSLWCHPKFEDRCQSVVEFIKRAIMHSKNGKFLYFLRSRVPGGCCGSDYKQYVFGGWAWAWWCISDTQRLSLEVMTILCRCENIE
TSEGVPLFVTGVAQVPCPCLLDCKWGNSKGFWKLCQVCQISLEIMTLQPRCEDVETAEGVALTVTGVAQVKIMTEKELLAVACEQFLGKN
VQDIKNVVLQTLEGHLRSILGTLTVEQIYQDRDQFAKLVREVAAPDVGRMGIEILSFTIKDVYDKVDYLSSLGKTQTAVVQRDADIGVAE
AERDAGIREAECKKEMLDVKFMADTKIADSKRAFELQKSAFSEEVNIKTAEAQLAYELQGAREQQKIRQEEIEIEVVQRKKQIAVEAQEI
LRTDKELIATVRRPAEAEAHRIQQIAEGEKVKQVLLAQAEAEKIRKIGEAEAAVIEAMGKAEAERMKLKAEAYQKYGDAAKMALVLEALP

--------------------------------------------------------------
>85096_85096_5_SOCS7-FLOT2_SOCS7_chr17_36533668_ENST00000577233_FLOT2_chr17_27216044_ENST00000394908_length(transcript)=3953nt_BP=1489nt
ATGGTGTTCCGCAACGTGGGTCGGCCGCCGGAGGAGGAGGACGTGGAGGCGGCCCCGGAGCCGGGACCCTCGGAACTGCTGTGTCCCCGG
CACCGCTGTGCCCTGGACCCCAAGGCCCTGCCGCCGGGCTTGGCGCTCGAGCGGACCTGGGGCCCGGCGGCTGGACTAGAGGCGCAGTTG
GCGGCTCTGGGGCTCGGGCAGCCGGCGGGGCCGGGGGTCAAGACAGTCGGTGGGGGTTGCTGCCCGTGTCCGTGTCCTCCTCAGCCGCCC
CCTCCGCAGCCCCAGCCGCCTGCTGCCGCCCCGCAGGCCGGGGAGGACCCCACGGAAACGAGCGACGCGCTGCTGGTCCTGGAGGGCTTG
GAATCGGAGGCCGAGAGCCTGGAGACTAACAGCTGCTCGGAAGAGGAGCTCAGCAGCCCGGGTCGCGGAGGAGGAGGGGGCGGCCGGCTT
CTGCTGCAGCCCCCAGGCCCTGAATTACCTCCGGTGCCCTTCCCGCTGCAGGACTTGGTCCCTCTGGGGCGCCTGAGTAGAGGGGAGCAG
CAGCAGCAGCAGCAGCAGCAACCTCCCCCGCCCCCGCCTCCTCCCGGGCCCCTCCGGCCACTCGCGGGTCCTTCTCGGAAGGGCTCCTTC
AAAATCCGCCTCAGTCGCCTCTTTCGCACCAAGAGCTGCAACGGTGGCTCCGGCGGTGGGGATGGGACCGGCAAGAGGCCTTCTGGAGAG
CTGGCTGCTTCAGCTGCGAGCCTGACAGACATGGGAGGCTCTGCGGGCCGGGAGCTGGACGCGGGGAGGAAACCCAAGTTGACAAGAACT
CAAAGTGCCTTTTCTCCGGTCTCCTTCAGCCCCCTGTTCACAGGTGAAACTGTGTCGCTTGTGGATGTGGACATTTCTCAGCGGGGCCTG
ACCTCTCCACACCCTCCAACTCCCCCTCCTCCTCCGAGAAGAAGCCTCAGCCTCCTAGATGATATCAGTGGGACGCTGCCTACATCTGTC
CTTGTGGCTCCGATGGGGTCTTCCTTGCAGTCTTTCCCCCTACCTCCGCCTCCTCCACCCCATGCCCCAGATGCATTTCCCCGGATTGCT
CCCATCCGAGCAGCTGAATCCCTGCACAGCCAACCCCCACAGCACCTCCAGTGTCCCCTCTACCGGCCTGACTCGAGCAGCTTTGCAGCC
AGCCTTCGAGAGTTGGAGAAGTGTGGTTGGTATTGGGGGCCAATGAATTGGGAAGATGCAGAGATGAAGCTGAAAGGGAAACCAGATGGT
TCTTTCCTGGTACGAGACAGTTCTGATCCTCGTTACATCCTGAGCCTCAGTTTCCGATCACAGGGTATCACCCACCACACTAGAATGGAG
CACTACAGAGGAACCTTCAGCCTGTGGTGTCATCCCAAGTTTGAGGACCGCTGTCAATCTGTTGTAGAGTTTATTAAGAGAGCCATTATG
CACTCCAAGAATGGAAAGTTTCTCTATTTCTTAAGATCCAGGGTTCCAGGGGGCTGTTGTGGTTCCGACTATAAACAGTACGTGTTTGGC
GGCTGGGCCTGGGCCTGGTGGTGTATCTCCGACACTCAGAGGATTTCCCTAGAGATTATGACGTTGCAGCCCCGCTGCGAGGACGTAGAG
ACGGCCGAGGGGGTAGCTTTAACTGTGACGGGTGTCGCCCAGGTGAAGATCATGACGGAGAAGGAACTCCTGGCCGTGGCTTGTGAGCAG
TTTCTGGGTAAGAATGTGCAGGACATCAAAAACGTCGTCCTGCAGACCCTGGAGGGACATCTGCGCTCCATCCTCGGGACCCTGACAGTG
GAGCAGATTTATCAGGACCGGGACCAGTTTGCCAAGCTGGTGCGGGAGGTGGCAGCCCCTGATGTTGGCCGCATGGGCATTGAGATCCTC
AGCTTCACCATCAAGGACGTGTATGACAAAGTGGACTATCTGAGCTCCCTGGGCAAGACGCAGACTGCCGTGGTGCAGAGAGATGCTGAC
ATTGGCGTGGCCGAGGCTGAACGGGACGCAGGCATCCGGGAAGCTGAGTGCAAGAAGGAGATGCTGGATGTGAAGTTCATGGCAGACACC
AAGATTGCTGACTCTAAGCGAGCCTTCGAGCTGCAAAAGTCAGCCTTCAGTGAGGAGGTTAACATCAAGACAGCTGAGGCCCAGTTGGCC
TATGAGCTGCAGGGGGCCCGTGAACAGCAGAAGATCCGGCAGGAAGAGATTGAGATTGAGGTTGTGCAGCGCAAGAAACAGATTGCCGTG
GAGGCACAGGAGATCCTGCGTACGGACAAGGAGCTCATCGCTACAGTGCGCCGGCCTGCCGAGGCCGAGGCCCACCGCATCCAGCAGATT
GCCGAGGGTGAAAAGGTGAAGCAGGTCCTCTTGGCACAGGCAGAGGCTGAGAAGATCCGCAAAATCGGGGAGGCGGAAGCGGCAGTCATC
GAGGCGATGGGCAAGGCAGAGGCTGAGCGGATGAAGCTCAAGGCAGAAGCCTACCAGAAATACGGGGATGCAGCCAAGATGGCCTTGGTG
CTAGAGGCCCTGCCCCAGATTGCTGCCAAAATCGCTGCCCCACTTACCAAGGTCGATGAGATTGTGGTCCTCAGTGGAGACAACAGTAAG
GTCACATCAGAAGTGAACCGACTGCTGGCCGAGCTGCCTGCCTCTGTGCATGCCCTCACAGGCGTGGACCTGTCTAAGATACCCCTGATC
AAGAAGGCCACTGGTGTGCAGGTGTGAGGCTCCTGCAGGCCCACTCTCTTCAGCAGCCACCCGGCCCTCCCTCCAGCACCCGTTTTAATC
CCACAGAACAACGGGAACGTTACTGACTCTGGTGCCTTATCTCGAAGGGACCAGAAGTGCTGCGTGTTCAGGCCATCTCTGGCTGTCTTC
CTGTCTCTCCTGTCTGTCCACCTCCTCCTCTTCCTCTCCTTTACCCCACTTTCACTGCCACTTTCATCAGGTTTGTGTCTCATCTCCCTG
CGTGTCTTTTCCTTTGTCTGTCTTTTTCTTTCCCCCATGCACATCATGTAGATTAAGCTGAAGATGTTTATTACAATCACTCTCTGTGGG
GGGTGGCCCTGCTGCTCCTCAGAATCCTGGTGCCTTGAAGTTCTCTGTGCATCTGTCCATCCTCCCTATGGCCCTGGCCAGAGCTCAGCA
TGGGCAGGGGTTCTGGGTAGGACGGTCACTGTCCTCTCTCCTGGACTGGTCTTCCCAGCCCTAAACCCTGCCCCAGGAAGCCCACAGCCT
CACCTGCTGCTGCCCCTCTAGGTCTGGGCAGCCATGACCTGCAGGGCCCAGAGACACTGTCCTTCCCCTCATCCACCCAAGGCCCCAGCC
AGCGCTCATACCCTGTCCTTTCTCCCTGACCCCAAGGGCACAGAGGCAAGGCCTCCTGTCTACAGCAGCTTCCTCAGTTTCCTACTGCCT
TAGGAGGCCCCTGCTTGTGCTCAGGGAAGGCCTCTTCATGGGCATGTTCCTGCTGGGGCGGTGCGGTTTGGTCCCAACTCTGCTAAGTTT
TCTGAGATGAGGGTCTAGCCCTGTTGGGGACAGAAAAGTGTGTAGACCTTCTTCCTGCTAGGGCTGCACTGTCCTGGGTGTTGGGCCCTT
CTGGTGGACAAGGCTGTGCCAACCCTGTACAGAATCGAGTGCTGTAGCCTGGCCAGACCCCAGAGCCCTTGTGCCATCTTTCTTCCTGGC
CAGAGTGATGGGGTTCCAGCCATGGGGAAGCAACCCAATCCTCTGTCTCCTTGCTCCAATGGAGGCAGAAGAGCCCAGGACCCAAGCGTC
TTGGCAGGGGTGCTGTGAATGTCCAGTGGTCCCAGCTCCCCACCCTGGCCCTGCCCCAGCCTGTGTAGCTCTTCCTGCATGTGGATGCTG

>85096_85096_5_SOCS7-FLOT2_SOCS7_chr17_36533668_ENST00000577233_FLOT2_chr17_27216044_ENST00000394908_length(amino acids)=908AA_BP=495
MVFRNVGRPPEEEDVEAAPEPGPSELLCPRHRCALDPKALPPGLALERTWGPAAGLEAQLAALGLGQPAGPGVKTVGGGCCPCPCPPQPP
PPQPQPPAAAPQAGEDPTETSDALLVLEGLESEAESLETNSCSEEELSSPGRGGGGGGRLLLQPPGPELPPVPFPLQDLVPLGRLSRGEQ
QQQQQQQPPPPPPPPGPLRPLAGPSRKGSFKIRLSRLFRTKSCNGGSGGGDGTGKRPSGELAASAASLTDMGGSAGRELDAGRKPKLTRT
QSAFSPVSFSPLFTGETVSLVDVDISQRGLTSPHPPTPPPPPRRSLSLLDDISGTLPTSVLVAPMGSSLQSFPLPPPPPPHAPDAFPRIA
PIRAAESLHSQPPQHLQCPLYRPDSSSFAASLRELEKCGWYWGPMNWEDAEMKLKGKPDGSFLVRDSSDPRYILSLSFRSQGITHHTRME
HYRGTFSLWCHPKFEDRCQSVVEFIKRAIMHSKNGKFLYFLRSRVPGGCCGSDYKQYVFGGWAWAWWCISDTQRISLEIMTLQPRCEDVE
TAEGVALTVTGVAQVKIMTEKELLAVACEQFLGKNVQDIKNVVLQTLEGHLRSILGTLTVEQIYQDRDQFAKLVREVAAPDVGRMGIEIL
SFTIKDVYDKVDYLSSLGKTQTAVVQRDADIGVAEAERDAGIREAECKKEMLDVKFMADTKIADSKRAFELQKSAFSEEVNIKTAEAQLA
YELQGAREQQKIRQEEIEIEVVQRKKQIAVEAQEILRTDKELIATVRRPAEAEAHRIQQIAEGEKVKQVLLAQAEAEKIRKIGEAEAAVI
EAMGKAEAERMKLKAEAYQKYGDAAKMALVLEALPQIAAKIAAPLTKVDEIVVLSGDNSKVTSEVNRLLAELPASVHALTGVDLSKIPLI

--------------------------------------------------------------
>85096_85096_6_SOCS7-FLOT2_SOCS7_chr17_36533668_ENST00000577233_FLOT2_chr17_27216044_ENST00000585169_length(transcript)=3947nt_BP=1489nt
ATGGTGTTCCGCAACGTGGGTCGGCCGCCGGAGGAGGAGGACGTGGAGGCGGCCCCGGAGCCGGGACCCTCGGAACTGCTGTGTCCCCGG
CACCGCTGTGCCCTGGACCCCAAGGCCCTGCCGCCGGGCTTGGCGCTCGAGCGGACCTGGGGCCCGGCGGCTGGACTAGAGGCGCAGTTG
GCGGCTCTGGGGCTCGGGCAGCCGGCGGGGCCGGGGGTCAAGACAGTCGGTGGGGGTTGCTGCCCGTGTCCGTGTCCTCCTCAGCCGCCC
CCTCCGCAGCCCCAGCCGCCTGCTGCCGCCCCGCAGGCCGGGGAGGACCCCACGGAAACGAGCGACGCGCTGCTGGTCCTGGAGGGCTTG
GAATCGGAGGCCGAGAGCCTGGAGACTAACAGCTGCTCGGAAGAGGAGCTCAGCAGCCCGGGTCGCGGAGGAGGAGGGGGCGGCCGGCTT
CTGCTGCAGCCCCCAGGCCCTGAATTACCTCCGGTGCCCTTCCCGCTGCAGGACTTGGTCCCTCTGGGGCGCCTGAGTAGAGGGGAGCAG
CAGCAGCAGCAGCAGCAGCAACCTCCCCCGCCCCCGCCTCCTCCCGGGCCCCTCCGGCCACTCGCGGGTCCTTCTCGGAAGGGCTCCTTC
AAAATCCGCCTCAGTCGCCTCTTTCGCACCAAGAGCTGCAACGGTGGCTCCGGCGGTGGGGATGGGACCGGCAAGAGGCCTTCTGGAGAG
CTGGCTGCTTCAGCTGCGAGCCTGACAGACATGGGAGGCTCTGCGGGCCGGGAGCTGGACGCGGGGAGGAAACCCAAGTTGACAAGAACT
CAAAGTGCCTTTTCTCCGGTCTCCTTCAGCCCCCTGTTCACAGGTGAAACTGTGTCGCTTGTGGATGTGGACATTTCTCAGCGGGGCCTG
ACCTCTCCACACCCTCCAACTCCCCCTCCTCCTCCGAGAAGAAGCCTCAGCCTCCTAGATGATATCAGTGGGACGCTGCCTACATCTGTC
CTTGTGGCTCCGATGGGGTCTTCCTTGCAGTCTTTCCCCCTACCTCCGCCTCCTCCACCCCATGCCCCAGATGCATTTCCCCGGATTGCT
CCCATCCGAGCAGCTGAATCCCTGCACAGCCAACCCCCACAGCACCTCCAGTGTCCCCTCTACCGGCCTGACTCGAGCAGCTTTGCAGCC
AGCCTTCGAGAGTTGGAGAAGTGTGGTTGGTATTGGGGGCCAATGAATTGGGAAGATGCAGAGATGAAGCTGAAAGGGAAACCAGATGGT
TCTTTCCTGGTACGAGACAGTTCTGATCCTCGTTACATCCTGAGCCTCAGTTTCCGATCACAGGGTATCACCCACCACACTAGAATGGAG
CACTACAGAGGAACCTTCAGCCTGTGGTGTCATCCCAAGTTTGAGGACCGCTGTCAATCTGTTGTAGAGTTTATTAAGAGAGCCATTATG
CACTCCAAGAATGGAAAGTTTCTCTATTTCTTAAGATCCAGGGTTCCAGGGGGCTGTTGTGGTTCCGACTATAAACAGTACGTGTTTGGC
GGCTGGGCCTGGGCCTGGTGGTGTATCTCCGACACTCAGAGACTGTCTCTGGAGGTTATGACCATCCTGTGTCGCTGTGAGAATATTGAG
ACGTCGGAGGGGGTTCCACTATTCGTAACAGGGGTTGCACAGGTGAAGATCATGACGGAGAAGGAACTCCTGGCCGTGGCTTGTGAGCAG
TTTCTGGGTAAGAATGTGCAGGACATCAAAAACGTCGTCCTGCAGACCCTGGAGGGACATCTGCGCTCCATCCTCGGGACCCTGACAGTG
GAGCAGATTTATCAGGACCGGGACCAGTTTGCCAAGCTGGTGCGGGAGGTGGCAGCCCCTGATGTTGGCCGCATGGGCATTGAGATCCTC
AGCTTCACCATCAAGGACGTGTATGACAAAGTGGACTATCTGAGCTCCCTGGGCAAGACGCAGACTGCCGTGGTGCAGAGAGATGCTGAC
ATTGGCGTGGCCGAGGCTGAACGGGACGCAGGCATCCGGGAAGCTGAGTGCAAGAAGGAGATGCTGGATGTGAAGTTCATGGCAGACACC
AAGATTGCTGACTCTAAGCGAGCCTTCGAGCTGCAAAAGTCAGCCTTCAGTGAGGAGGTTAACATCAAGACAGCTGAGGCCCAGTTGGCC
TATGAGCTGCAGGGGGCCCGTGAACAGCAGAAGATCCGGCAGGAAGAGATTGAGATTGAGGTTGTGCAGCGCAAGAAACAGATTGCCGTG
GAGGCACAGGAGATCCTGCGTACGGACAAGGAGCTCATCGCTACAGTGCGCCGGCCTGCCGAGGCCGAGGCCCACCGCATCCAGCAGATT
GCCGAGGGTGAAAAGGTGAAGCAGGTCCTCTTGGCACAGGCAGAGGCTGAGAAGATCCGCAAAATCGGGGAGGCGGAAGCGGCAGTCATC
GAGGCGATGGGCAAGGCAGAGGCTGAGCGGATGAAGCTCAAGGCAGAAGCCTACCAGAAATACGGGGATGCAGCCAAGATGGCCTTGGTG
CTAGAGGCCCTGCCCCAGATTGCTGCCAAAATCGCTGCCCCACTTACCAAGGTCGATGAGATTGTGGTCCTCAGTGGAGACAACAGTAAG
GTCACATCAGAAGTGAACCGACTGCTGGCCGAGCTGCCTGCCTCTGTGCATGCCCTCACAGGCGTGGACCTGTCTAAGATACCCCTGATC
AAGAAGGCCACTGGTGTGCAGGTGTGAGGCTCCTGCAGGCCCACTCTCTTCAGCAGCCACCCGGCCCTCCCTCCAGCACCCGTTTTAATC
CCACAGAACAACGGGAACGTTACTGACTCTGGTGCCTTATCTCGAAGGGACCAGAAGTGCTGCGTGTTCAGGCCATCTCTGGCTGTCTTC
CTGTCTCTCCTGTCTGTCCACCTCCTCCTCTTCCTCTCCTTTACCCCACTTTCACTGCCACTTTCATCAGGTTTGTGTCTCATCTCCCTG
CGTGTCTTTTCCTTTGTCTGTCTTTTTCTTTCCCCCATGCACATCATGTAGATTAAGCTGAAGATGTTTATTACAATCACTCTCTGTGGG
GGGTGGCCCTGCTGCTCCTCAGAATCCTGGTGCCTTGAAGTTCTCTGTGCATCTGTCCATCCTCCCTATGGCCCTGGCCAGAGCTCAGCA
TGGGCAGGGGTTCTGGGTAGGACGGTCACTGTCCTCTCTCCTGGACTGGTCTTCCCAGCCCTAAACCCTGCCCCAGGAAGCCCACAGCCT
CACCTGCTGCTGCCCCTCTAGGTCTGGGCAGCCATGACCTGCAGGGCCCAGAGACACTGTCCTTCCCCTCATCCACCCAAGGCCCCAGCC
AGCGCTCATACCCTGTCCTTTCTCCCTGACCCCAAGGGCACAGAGGCAAGGCCTCCTGTCTACAGCAGCTTCCTCAGTTTCCTACTGCCT
TAGGAGGCCCCTGCTTGTGCTCAGGGAAGGCCTCTTCATGGGCATGTTCCTGCTGGGGCGGTGCGGTTTGGTCCCAACTCTGCTAAGTTT
TCTGAGATGAGGGTCTAGCCCTGTTGGGGACAGAAAAGTGTGTAGACCTTCTTCCTGCTAGGGCTGCACTGTCCTGGGTGTTGGGCCCTT
CTGGTGGACAAGGCTGTGCCAACCCTGTACAGAATCGAGTGCTGTAGCCTGGCCAGACCCCAGAGCCCTTGTGCCATCTTTCTTCCTGGC
CAGAGTGATGGGGTTCCAGCCATGGGGAAGCAACCCAATCCTCTGTCTCCTTGCTCCAATGGAGGCAGAAGAGCCCAGGACCCAAGCGTC
TTGGCAGGGGTGCTGTGAATGTCCAGTGGTCCCAGCTCCCCACCCTGGCCCTGCCCCAGCCTGTGTAGCTCTTCCTGCATGTGGATGCTG

>85096_85096_6_SOCS7-FLOT2_SOCS7_chr17_36533668_ENST00000577233_FLOT2_chr17_27216044_ENST00000585169_length(amino acids)=908AA_BP=495
MVFRNVGRPPEEEDVEAAPEPGPSELLCPRHRCALDPKALPPGLALERTWGPAAGLEAQLAALGLGQPAGPGVKTVGGGCCPCPCPPQPP
PPQPQPPAAAPQAGEDPTETSDALLVLEGLESEAESLETNSCSEEELSSPGRGGGGGGRLLLQPPGPELPPVPFPLQDLVPLGRLSRGEQ
QQQQQQQPPPPPPPPGPLRPLAGPSRKGSFKIRLSRLFRTKSCNGGSGGGDGTGKRPSGELAASAASLTDMGGSAGRELDAGRKPKLTRT
QSAFSPVSFSPLFTGETVSLVDVDISQRGLTSPHPPTPPPPPRRSLSLLDDISGTLPTSVLVAPMGSSLQSFPLPPPPPPHAPDAFPRIA
PIRAAESLHSQPPQHLQCPLYRPDSSSFAASLRELEKCGWYWGPMNWEDAEMKLKGKPDGSFLVRDSSDPRYILSLSFRSQGITHHTRME
HYRGTFSLWCHPKFEDRCQSVVEFIKRAIMHSKNGKFLYFLRSRVPGGCCGSDYKQYVFGGWAWAWWCISDTQRLSLEVMTILCRCENIE
TSEGVPLFVTGVAQVKIMTEKELLAVACEQFLGKNVQDIKNVVLQTLEGHLRSILGTLTVEQIYQDRDQFAKLVREVAAPDVGRMGIEIL
SFTIKDVYDKVDYLSSLGKTQTAVVQRDADIGVAEAERDAGIREAECKKEMLDVKFMADTKIADSKRAFELQKSAFSEEVNIKTAEAQLA
YELQGAREQQKIRQEEIEIEVVQRKKQIAVEAQEILRTDKELIATVRRPAEAEAHRIQQIAEGEKVKQVLLAQAEAEKIRKIGEAEAAVI
EAMGKAEAERMKLKAEAYQKYGDAAKMALVLEALPQIAAKIAAPLTKVDEIVVLSGDNSKVTSEVNRLLAELPASVHALTGVDLSKIPLI

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Fusion Gene PPI Analysis for SOCS7-FLOT2


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for SOCS7-FLOT2


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for SOCS7-FLOT2


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource