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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:SOGA3-NPC1L1 (FusionGDB2 ID:85146)

Fusion Gene Summary for SOGA3-NPC1L1

check button Fusion gene summary
Fusion gene informationFusion gene name: SOGA3-NPC1L1
Fusion gene ID: 85146
HgeneTgene
Gene symbol

SOGA3

NPC1L1

Gene ID

387104

29881

Gene nameSOGA family member 3NPC1 like intracellular cholesterol transporter 1
SynonymsC6orf174|dJ403A15.3LDLCQ7|NPC11L1|SLC65A2
Cytomap

6q22.33

7p13

Type of geneprotein-codingprotein-coding
Descriptionprotein SOGA3NPC1-like intracellular cholesterol transporter 1NPC1 (Niemann-Pick disease, type C1, gene)-like 1NPC1 like 1niemann-Pick C1-like protein 1
Modification date2020031320200322
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000368268, ENST00000481848, 
ENST00000525778, ENST00000556132, 
ENST00000474293, ENST00000465909, 
ENST00000381160, ENST00000423141, 
ENST00000546276, ENST00000289547, 
Fusion gene scores* DoF score3 X 2 X 3=183 X 2 X 2=12
# samples 32
** MAII scorelog2(3/18*10)=0.736965594166206
effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs).
DoF>8 and MAII>0		log2(2/12*10)=0.736965594166206
effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs).
DoF>8 and MAII>0
Context

PubMed: SOGA3 [Title/Abstract] AND NPC1L1 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointSOGA3(127796438)-NPC1L1(44561841), # samples:1
Anticipated loss of major functional domain due to fusion event.SOGA3-NPC1L1 seems lost the major protein functional domain in Tgene partner, which is a IUPHAR drug target due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
TgeneNPC1L1

GO:0071501

cellular response to sterol depletion

19325169


check buttonFusion gene breakpoints across SOGA3 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across NPC1L1 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4SKCMTCGA-EE-A181-06ASOGA3chr6

127796438

-NPC1L1chr7

44561841

-


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Fusion Gene ORF analysis for SOGA3-NPC1L1

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000368268ENST00000381160SOGA3chr6

127796438

-NPC1L1chr7

44561841

-
5CDS-intronENST00000368268ENST00000423141SOGA3chr6

127796438

-NPC1L1chr7

44561841

-
5CDS-intronENST00000368268ENST00000546276SOGA3chr6

127796438

-NPC1L1chr7

44561841

-
5CDS-intronENST00000481848ENST00000381160SOGA3chr6

127796438

-NPC1L1chr7

44561841

-
5CDS-intronENST00000481848ENST00000423141SOGA3chr6

127796438

-NPC1L1chr7

44561841

-
5CDS-intronENST00000481848ENST00000546276SOGA3chr6

127796438

-NPC1L1chr7

44561841

-
5CDS-intronENST00000525778ENST00000381160SOGA3chr6

127796438

-NPC1L1chr7

44561841

-
5CDS-intronENST00000525778ENST00000423141SOGA3chr6

127796438

-NPC1L1chr7

44561841

-
5CDS-intronENST00000525778ENST00000546276SOGA3chr6

127796438

-NPC1L1chr7

44561841

-
5CDS-intronENST00000556132ENST00000381160SOGA3chr6

127796438

-NPC1L1chr7

44561841

-
5CDS-intronENST00000556132ENST00000423141SOGA3chr6

127796438

-NPC1L1chr7

44561841

-
5CDS-intronENST00000556132ENST00000546276SOGA3chr6

127796438

-NPC1L1chr7

44561841

-
5UTR-3CDSENST00000474293ENST00000289547SOGA3chr6

127796438

-NPC1L1chr7

44561841

-
5UTR-intronENST00000474293ENST00000381160SOGA3chr6

127796438

-NPC1L1chr7

44561841

-
5UTR-intronENST00000474293ENST00000423141SOGA3chr6

127796438

-NPC1L1chr7

44561841

-
5UTR-intronENST00000474293ENST00000546276SOGA3chr6

127796438

-NPC1L1chr7

44561841

-
Frame-shiftENST00000525778ENST00000289547SOGA3chr6

127796438

-NPC1L1chr7

44561841

-
In-frameENST00000368268ENST00000289547SOGA3chr6

127796438

-NPC1L1chr7

44561841

-
In-frameENST00000481848ENST00000289547SOGA3chr6

127796438

-NPC1L1chr7

44561841

-
In-frameENST00000556132ENST00000289547SOGA3chr6

127796438

-NPC1L1chr7

44561841

-
intron-3CDSENST00000465909ENST00000289547SOGA3chr6

127796438

-NPC1L1chr7

44561841

-
intron-intronENST00000465909ENST00000381160SOGA3chr6

127796438

-NPC1L1chr7

44561841

-
intron-intronENST00000465909ENST00000423141SOGA3chr6

127796438

-NPC1L1chr7

44561841

-
intron-intronENST00000465909ENST00000546276SOGA3chr6

127796438

-NPC1L1chr7

44561841

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000481848SOGA3chr6127796438-ENST00000289547NPC1L1chr744561841-5599324451146861391
ENST00000556132SOGA3chr6127796438-ENST00000289547NPC1L1chr744561841-5953359886550401391
ENST00000368268SOGA3chr6127796438-ENST00000289547NPC1L1chr744561841-50882733041751391

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000481848ENST00000289547SOGA3chr6127796438-NPC1L1chr744561841-0.0128554130.98714465
ENST00000556132ENST00000289547SOGA3chr6127796438-NPC1L1chr744561841-0.0145471350.98545283
ENST00000368268ENST00000289547SOGA3chr6127796438-NPC1L1chr744561841-0.0109882490.98901176

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Fusion Genomic Features for SOGA3-NPC1L1


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for SOGA3-NPC1L1


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr6:127796438/chr7:44561841)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneSOGA3chr6:127796438chr7:44561841ENST00000368268-58342_726911698.0Coiled coilOntology_term=ECO:0000255
HgeneSOGA3chr6:127796438chr7:44561841ENST00000368268-58811_835911698.0Coiled coilOntology_term=ECO:0000255
HgeneSOGA3chr6:127796438chr7:44561841ENST00000525778-67342_726911948.0Coiled coilOntology_term=ECO:0000255
HgeneSOGA3chr6:127796438chr7:44561841ENST00000525778-67811_835911948.0Coiled coilOntology_term=ECO:0000255
HgeneSOGA3chr6:127796438chr7:44561841ENST00000556132-612342_7269112488.6666666666665Coiled coilOntology_term=ECO:0000255
HgeneSOGA3chr6:127796438chr7:44561841ENST00000556132-612811_8359112488.6666666666665Coiled coilOntology_term=ECO:0000255
HgeneSOGA3chr6:127796438chr7:44561841ENST00000368268-58269_276911698.0Compositional biasNote=Poly-Ala
HgeneSOGA3chr6:127796438chr7:44561841ENST00000368268-5872_81911698.0Compositional biasNote=Poly-Gln
HgeneSOGA3chr6:127796438chr7:44561841ENST00000368268-5882_247911698.0Compositional biasNote=Gly-rich
HgeneSOGA3chr6:127796438chr7:44561841ENST00000525778-67269_276911948.0Compositional biasNote=Poly-Ala
HgeneSOGA3chr6:127796438chr7:44561841ENST00000525778-6772_81911948.0Compositional biasNote=Poly-Gln
HgeneSOGA3chr6:127796438chr7:44561841ENST00000525778-6782_247911948.0Compositional biasNote=Gly-rich
HgeneSOGA3chr6:127796438chr7:44561841ENST00000556132-612269_2769112488.6666666666665Compositional biasNote=Poly-Ala
HgeneSOGA3chr6:127796438chr7:44561841ENST00000556132-61272_819112488.6666666666665Compositional biasNote=Poly-Gln
HgeneSOGA3chr6:127796438chr7:44561841ENST00000556132-61282_2479112488.6666666666665Compositional biasNote=Gly-rich
HgeneSOGA3chr6:127796438chr7:44561841ENST00000368268-58915_935911698.0TransmembraneHelical
TgeneNPC1L1chr6:127796438chr7:44561841ENST0000042314107500_5030725.0Compositional biasNote=Poly-Leu
TgeneNPC1L1chr6:127796438chr7:44561841ENST0000042314107632_7970725.0DomainSSD
TgeneNPC1L1chr6:127796438chr7:44561841ENST000002895479201161_11688791360.0Topological domainCytoplasmic
TgeneNPC1L1chr6:127796438chr7:44561841ENST000002895479201190_11918791360.0Topological domainExtracellular
TgeneNPC1L1chr6:127796438chr7:44561841ENST000002895479201213_12368791360.0Topological domainCytoplasmic
TgeneNPC1L1chr6:127796438chr7:44561841ENST000002895479201258_12688791360.0Topological domainExtracellular
TgeneNPC1L1chr6:127796438chr7:44561841ENST000002895479201290_13598791360.0Topological domainCytoplasmic
TgeneNPC1L1chr6:127796438chr7:44561841ENST000003811609191161_11688791333.0Topological domainCytoplasmic
TgeneNPC1L1chr6:127796438chr7:44561841ENST000003811609191190_11918791333.0Topological domainExtracellular
TgeneNPC1L1chr6:127796438chr7:44561841ENST000003811609191213_12368791333.0Topological domainCytoplasmic
TgeneNPC1L1chr6:127796438chr7:44561841ENST000003811609191258_12688791333.0Topological domainExtracellular
TgeneNPC1L1chr6:127796438chr7:44561841ENST000003811609191290_13598791333.0Topological domainCytoplasmic
TgeneNPC1L1chr6:127796438chr7:44561841ENST00000423141071161_11680725.0Topological domainCytoplasmic
TgeneNPC1L1chr6:127796438chr7:44561841ENST00000423141071190_11910725.0Topological domainExtracellular
TgeneNPC1L1chr6:127796438chr7:44561841ENST00000423141071213_12360725.0Topological domainCytoplasmic
TgeneNPC1L1chr6:127796438chr7:44561841ENST00000423141071258_12680725.0Topological domainExtracellular
TgeneNPC1L1chr6:127796438chr7:44561841ENST00000423141071290_13590725.0Topological domainCytoplasmic
TgeneNPC1L1chr6:127796438chr7:44561841ENST000004231410722_2840725.0Topological domainExtracellular
TgeneNPC1L1chr6:127796438chr7:44561841ENST0000042314107306_3510725.0Topological domainCytoplasmic
TgeneNPC1L1chr6:127796438chr7:44561841ENST0000042314107373_6320725.0Topological domainExtracellular
TgeneNPC1L1chr6:127796438chr7:44561841ENST0000042314107654_6660725.0Topological domainCytoplasmic
TgeneNPC1L1chr6:127796438chr7:44561841ENST0000042314107688_6960725.0Topological domainExtracellular
TgeneNPC1L1chr6:127796438chr7:44561841ENST0000042314107718_7420725.0Topological domainCytoplasmic
TgeneNPC1L1chr6:127796438chr7:44561841ENST0000042314107764_7760725.0Topological domainExtracellular
TgeneNPC1L1chr6:127796438chr7:44561841ENST0000042314107798_8460725.0Topological domainCytoplasmic
TgeneNPC1L1chr6:127796438chr7:44561841ENST0000042314107868_11390725.0Topological domainExtracellular
TgeneNPC1L1chr6:127796438chr7:44561841ENST000002895479201140_11608791360.0TransmembraneHelical%3B Name%3D9
TgeneNPC1L1chr6:127796438chr7:44561841ENST000002895479201169_11898791360.0TransmembraneHelical%3B Name%3D10
TgeneNPC1L1chr6:127796438chr7:44561841ENST000002895479201192_12128791360.0TransmembraneHelical%3B Name%3D11
TgeneNPC1L1chr6:127796438chr7:44561841ENST000002895479201237_12578791360.0TransmembraneHelical%3B Name%3D12
TgeneNPC1L1chr6:127796438chr7:44561841ENST000002895479201269_12898791360.0TransmembraneHelical%3B Name%3D13
TgeneNPC1L1chr6:127796438chr7:44561841ENST000003811609191140_11608791333.0TransmembraneHelical%3B Name%3D9
TgeneNPC1L1chr6:127796438chr7:44561841ENST000003811609191169_11898791333.0TransmembraneHelical%3B Name%3D10
TgeneNPC1L1chr6:127796438chr7:44561841ENST000003811609191192_12128791333.0TransmembraneHelical%3B Name%3D11
TgeneNPC1L1chr6:127796438chr7:44561841ENST000003811609191237_12578791333.0TransmembraneHelical%3B Name%3D12
TgeneNPC1L1chr6:127796438chr7:44561841ENST000003811609191269_12898791333.0TransmembraneHelical%3B Name%3D13
TgeneNPC1L1chr6:127796438chr7:44561841ENST00000423141071140_11600725.0TransmembraneHelical%3B Name%3D9
TgeneNPC1L1chr6:127796438chr7:44561841ENST00000423141071169_11890725.0TransmembraneHelical%3B Name%3D10
TgeneNPC1L1chr6:127796438chr7:44561841ENST00000423141071192_12120725.0TransmembraneHelical%3B Name%3D11
TgeneNPC1L1chr6:127796438chr7:44561841ENST00000423141071237_12570725.0TransmembraneHelical%3B Name%3D12
TgeneNPC1L1chr6:127796438chr7:44561841ENST00000423141071269_12890725.0TransmembraneHelical%3B Name%3D13
TgeneNPC1L1chr6:127796438chr7:44561841ENST0000042314107285_3050725.0TransmembraneHelical%3B Name%3D1
TgeneNPC1L1chr6:127796438chr7:44561841ENST0000042314107352_3720725.0TransmembraneHelical%3B Name%3D2
TgeneNPC1L1chr6:127796438chr7:44561841ENST0000042314107633_6530725.0TransmembraneHelical%3B Name%3D3
TgeneNPC1L1chr6:127796438chr7:44561841ENST0000042314107667_6870725.0TransmembraneHelical%3B Name%3D4
TgeneNPC1L1chr6:127796438chr7:44561841ENST0000042314107697_7170725.0TransmembraneHelical%3B Name%3D5
TgeneNPC1L1chr6:127796438chr7:44561841ENST0000042314107743_7630725.0TransmembraneHelical%3B Name%3D6
TgeneNPC1L1chr6:127796438chr7:44561841ENST0000042314107777_7970725.0TransmembraneHelical%3B Name%3D7
TgeneNPC1L1chr6:127796438chr7:44561841ENST0000042314107847_8670725.0TransmembraneHelical%3B Name%3D8

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneSOGA3chr6:127796438chr7:44561841ENST00000525778-67915_935911948.0TransmembraneHelical
HgeneSOGA3chr6:127796438chr7:44561841ENST00000556132-612915_9359112488.6666666666665TransmembraneHelical
TgeneNPC1L1chr6:127796438chr7:44561841ENST00000289547920500_5038791360.0Compositional biasNote=Poly-Leu
TgeneNPC1L1chr6:127796438chr7:44561841ENST00000381160919500_5038791333.0Compositional biasNote=Poly-Leu
TgeneNPC1L1chr6:127796438chr7:44561841ENST00000289547920632_7978791360.0DomainSSD
TgeneNPC1L1chr6:127796438chr7:44561841ENST00000381160919632_7978791333.0DomainSSD
TgeneNPC1L1chr6:127796438chr7:44561841ENST0000028954792022_2848791360.0Topological domainExtracellular
TgeneNPC1L1chr6:127796438chr7:44561841ENST00000289547920306_3518791360.0Topological domainCytoplasmic
TgeneNPC1L1chr6:127796438chr7:44561841ENST00000289547920373_6328791360.0Topological domainExtracellular
TgeneNPC1L1chr6:127796438chr7:44561841ENST00000289547920654_6668791360.0Topological domainCytoplasmic
TgeneNPC1L1chr6:127796438chr7:44561841ENST00000289547920688_6968791360.0Topological domainExtracellular
TgeneNPC1L1chr6:127796438chr7:44561841ENST00000289547920718_7428791360.0Topological domainCytoplasmic
TgeneNPC1L1chr6:127796438chr7:44561841ENST00000289547920764_7768791360.0Topological domainExtracellular
TgeneNPC1L1chr6:127796438chr7:44561841ENST00000289547920798_8468791360.0Topological domainCytoplasmic
TgeneNPC1L1chr6:127796438chr7:44561841ENST00000289547920868_11398791360.0Topological domainExtracellular
TgeneNPC1L1chr6:127796438chr7:44561841ENST0000038116091922_2848791333.0Topological domainExtracellular
TgeneNPC1L1chr6:127796438chr7:44561841ENST00000381160919306_3518791333.0Topological domainCytoplasmic
TgeneNPC1L1chr6:127796438chr7:44561841ENST00000381160919373_6328791333.0Topological domainExtracellular
TgeneNPC1L1chr6:127796438chr7:44561841ENST00000381160919654_6668791333.0Topological domainCytoplasmic
TgeneNPC1L1chr6:127796438chr7:44561841ENST00000381160919688_6968791333.0Topological domainExtracellular
TgeneNPC1L1chr6:127796438chr7:44561841ENST00000381160919718_7428791333.0Topological domainCytoplasmic
TgeneNPC1L1chr6:127796438chr7:44561841ENST00000381160919764_7768791333.0Topological domainExtracellular
TgeneNPC1L1chr6:127796438chr7:44561841ENST00000381160919798_8468791333.0Topological domainCytoplasmic
TgeneNPC1L1chr6:127796438chr7:44561841ENST00000381160919868_11398791333.0Topological domainExtracellular
TgeneNPC1L1chr6:127796438chr7:44561841ENST00000289547920285_3058791360.0TransmembraneHelical%3B Name%3D1
TgeneNPC1L1chr6:127796438chr7:44561841ENST00000289547920352_3728791360.0TransmembraneHelical%3B Name%3D2
TgeneNPC1L1chr6:127796438chr7:44561841ENST00000289547920633_6538791360.0TransmembraneHelical%3B Name%3D3
TgeneNPC1L1chr6:127796438chr7:44561841ENST00000289547920667_6878791360.0TransmembraneHelical%3B Name%3D4
TgeneNPC1L1chr6:127796438chr7:44561841ENST00000289547920697_7178791360.0TransmembraneHelical%3B Name%3D5
TgeneNPC1L1chr6:127796438chr7:44561841ENST00000289547920743_7638791360.0TransmembraneHelical%3B Name%3D6
TgeneNPC1L1chr6:127796438chr7:44561841ENST00000289547920777_7978791360.0TransmembraneHelical%3B Name%3D7
TgeneNPC1L1chr6:127796438chr7:44561841ENST00000289547920847_8678791360.0TransmembraneHelical%3B Name%3D8
TgeneNPC1L1chr6:127796438chr7:44561841ENST00000381160919285_3058791333.0TransmembraneHelical%3B Name%3D1
TgeneNPC1L1chr6:127796438chr7:44561841ENST00000381160919352_3728791333.0TransmembraneHelical%3B Name%3D2
TgeneNPC1L1chr6:127796438chr7:44561841ENST00000381160919633_6538791333.0TransmembraneHelical%3B Name%3D3
TgeneNPC1L1chr6:127796438chr7:44561841ENST00000381160919667_6878791333.0TransmembraneHelical%3B Name%3D4
TgeneNPC1L1chr6:127796438chr7:44561841ENST00000381160919697_7178791333.0TransmembraneHelical%3B Name%3D5
TgeneNPC1L1chr6:127796438chr7:44561841ENST00000381160919743_7638791333.0TransmembraneHelical%3B Name%3D6
TgeneNPC1L1chr6:127796438chr7:44561841ENST00000381160919777_7978791333.0TransmembraneHelical%3B Name%3D7
TgeneNPC1L1chr6:127796438chr7:44561841ENST00000381160919847_8678791333.0TransmembraneHelical%3B Name%3D8


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Fusion Gene Sequence for SOGA3-NPC1L1


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>85146_85146_1_SOGA3-NPC1L1_SOGA3_chr6_127796438_ENST00000368268_NPC1L1_chr7_44561841_ENST00000289547_length(transcript)=5088nt_BP=2733nt
ATGAGTCAGCCACCAATCGGGGGCGCTGCCCCTGCCACAGCAGCAGCTTCTCCCGCCGCTGCAGCCACTGAGGCTCGTCTGCACCCGGAG
GGCAGCAGCAGAAAGCAGCAGCGAGCTCAGTCACCCGCTAGACCGAGGGACAGTTCGCTGCGACAGACAATCGCGGCCACCCGGTCCCCA
GTGGGGGCCGGCACTAAACTCAATTCTGTTCGGCAGCAGCAGCTGCAGCAGCAGCAACAGCAGGGTAACAAGACCGGGAGCCGCACGGGG
CCGCCCGCCAGCATCCGAGGAGGCGGAGGTGGGGCCGAGAAGGCGACGCCCCTGGCGCCCAAAGGGGCCGCTCCGGGAGCTGTCCAGCCT
GTGGCTGGTGCTGAAGCGGCCCCCGCCGCGACCCTGGCCGCTTTGGGCGGCAGGAGGCCCGGACCGCCCGAGGAGCCGCCTCGGGAGCTA
GAGTCCGTGCCCTCGAAACTCGGGGAACCCCCTCCGCTCGGAGAAGGGGGAGGAGGGGGCGGGGAAGGAGGAGGAGCCGGCGGCGGCTCC
GGGGAAAGGGAGGGGGGCGCTCCGCAGCCGCCGCCGCCCAGGGGCTGGCGAGGGAAAGGCGTACGCGCTCAGCAGAGGGGCGGCAGCGGC
GGGGAGGGGGCCTCCCCTTCTCCATCCTCCTCTTCTGCGGGCAAAACCCCAGGAACCGGCAGCAGAAACTCCGGAAGCGGCGTTGCGGGG
GGCGGCAGCGGTGGTGGAGGGAGCTACTGGAAAGAAGGATGTCTGCAGTCTGAGCTCATCCAGTTCCATCTCAAGAAGGAGCGGGCGGCA
GCGGCGGCGGCCGCGGCTCAGATGCACGCTAAGAACGGCGGCGGCAGCAGTAGCCGCAGCTCCCCGGTGTCTGGCCCCCCTGCCGTTTGC
GAGACCCTGGCCGTCGCCTCCGCCTCCCCAATGGCGGCGGCGGCGGAGGGCCCCCAGCAGAGCGCAGAGGGCAGCGCGAGCGGCGGGGGC
ATGCAGGCGGCAGCGCCCCCTTCGTCGCAGCCGCACCCGCAGCAGCTCCAAGAGCAGGAAGAAATGCAAGAGGAGATGGAGAAGCTGCGA
GAGGAAAACGAGACTCTCAAGAACGAGATCGATGAGCTGAGAACCGAGATGGACGAGATGAGGGACACTTTCTTCGAGGAGGATGCCTGT
CAACTGCAGGAAATGCGCCACGAGTTGGAGAGAGCCAACAAAAACTGCCGGATCCTGCAGTACCGCCTCCGCAAAGCCGAGCGCAAAAGG
CTCCGCTACGCCCAGACCGGGGAAATCGACGGGGAGCTGTTGCGCAGCCTGGAGCAGGACCTCAAGGTTGCAAAGGATGTATCTGTGAGA
CTTCACCATGAATTAGAAAATGTGGAAGAAAAGAGAACAACAACAGAAGATGAAAATGAGAAACTGAGGCAACAGCTCATAGAAGTTGAA
ATTGCAAAGCAAGCTTTACAGAATGAACTGGAAAAAATGAAAGAGTTATCCTTAAAAAGAAGAGGAAGCAAAGATTTGCCAAAATCTGAA
AAAAAGGCTCAACAGACTCCCACAGAGGAGGACAATGAAGATCTGAAGTGCCAGCTGCAGTTTGTTAAGGAAGAAGCCGCTTTGATGAGA
AAGAAAATGGCCAAGATTGATAAAGAAAAGGACAGATTTGAACACGAGCTCCAGAAGTACAGATCCTTTTATGGGGATCTGGACAGTCCT
TTGCCCAAAGGAGAAGCCGGAGGCCCTCCCAGCACTAGGGAGGCCGAGCTCAAGCTACGGCTAAGGCTGGTGGAGGAAGAAGCCAACATC
CTGGGCAGGAAAATCGTCGAACTGGAGGTGGAGAACAGAGGCCTGAAGGCGGAACTGGACGACCTTAGGGGCGATGACTTCAACGGCTCG
GCCAACCCGCTCATGAGGGAGCAGAGCGAATCCCTGTCGGAGCTGCGGCAGCACCTGCAGCTGGTGGAAGACGAGACGGAGCTGCTGCGG
AGGAACGTGGCCGACCTGGAGGAGCAGAACAAGCGCATCACGGCGGAGCTCAACAAGTACAAGTACAAGTCCGGCGGCCACGACAGCGCG
CGGCACCACGACAACGCCAAGACCGAGGCCCTGCAGGAGGAGCTGAAGGCGGCGCGCCTGCAGATCAACGAGCTCAGCGGCAAGGTCATG
CAGCTGCAGTACGAGAACCGCGTGCTTATGTCCAACATGCAGCGCTACGACCTGGCCTCGCACCTGGGCATCCGCGGCAGCCCCCGCGAC
AGCGACGCCGAGAGCGACGCGGGCAAGAAGGAGAGCGACGACGACTCGCGGCCTCCGCACCGCAAGCGCGAAGGGCCCATCGGCGGCGAG
AGCGACTCGGAGGAGGTGCGCAACATCCGCTGCCTCACGCCCACTCGCTCCTTCTACCCGGCGCCCGGGCCCTGGCCCAAGAGCTTCTCC
GATCGGCAGCAGATGAAGGACATCCGCTCGGAGGCCGAGCGCCTGGGCAAGACCATCGACCGGCTCATCGCCGACACGAGCACCATCATC
ACCGAGGCGCGCATCTACGTGGCCAACGGGGACCTGTTCGGACTCATGGACGAGGAGGACGACGGCAGCCGCATCCGGGAGCACGAGCTG
CTCTACCGCATCAACGCTCAGATGAAGGCCTTCCGCAAGGAGCTGCAGACCTTCATCGACCGCCTCGAGGTGCCCAAGTCTGCGGACGAC
CGCGGCGCCGAGGAGCCCATTTCCGTGAGTCAGGACTCGTACCTGCTTGACTATTTCCTCTTTCTGAACCGCTACTTCGAGGTGGGGGCC
CCGGTGTACTTTGTTACCACCTTGGGCTACAACTTCTCCAGCGAGGCTGGGATGAATGCCATCTGCTCCAGTGCAGGCTGCAACAACTTC
TCCTTCACCCAGAAGATCCAGTATGCCACAGAGTTCCCTGAGCAGTCTTACCTGGCCATCCCTGCCTCCTCCTGGGTGGATGACTTCATT
GACTGGCTGACCCCGTCCTCCTGCTGCCGCCTTTATATATCTGGCCCCAATAAGGACAAGTTCTGCCCCTCGACCGTCAACTCTCTGAAC
TGCCTAAAGAACTGCATGAGCATCACGATGGGCTCTGTGAGGCCCTCGGTGGAGCAGTTCCATAAGTATCTTCCCTGGTTCCTGAACGAC
CGGCCCAACATCAAATGTCCCAAAGGCGGCCTGGCAGCATACAGCACCTCTGTGAACTTGACTTCAGATGGCCAGGTTTTAGACACAGTT
GCCATTCTGTCACCCAGGCTGGAGTACAGTGGCACAATCTCGGCTCACTGCAACCTCTACCTCCTGGATTCAACCTCCAGGTTCATGGCC
TATCACAAGCCCCTGAAAAACTCACAGGATTACACAGAAGCTCTGCGGGCAGCTCGAGAGCTGGCAGCCAACATCACTGCTGACCTGCGG
AAAGTGCCTGGAACAGACCCGGCTTTTGAGGTCTTCCCCTACACGATCACCAATGTGTTTTATGAGCAGTACCTGACCATCCTCCCTGAG
GGGCTCTTCATGCTCAGCCTCTGCCTTGTGCCCACCTTCGCTGTCTCCTGCCTCCTGCTGGGCCTGGACCTGCGCTCCGGCCTCCTCAAC
CTGCTCTCCATTGTCATGATCCTCGTGGACACTGTCGGCTTCATGGCCCTGTGGGGCATCAGTTACAATGCTGTGTCCCTCATCAACCTG
GTCTCGGCGGTGGGCATGTCTGTGGAGTTTGTGTCCCACATTACCCGCTCCTTTGCCATCAGCACCAAGCCCACCTGGCTGGAGAGGGCC
AAAGAGGCCACCATCTCTATGGGAAGTGCGGTGTTTGCAGGTGTGGCCATGACCAACCTGCCTGGCATCCTTGTCCTGGGCCTCGCCAAG
GCCCAGCTCATTCAGATCTTCTTCTTCCGCCTCAACCTCCTGATCACTCTGCTGGGCCTGCTGCATGGCTTGGTCTTCCTGCCCGTCATC
CTCAGCTACGTGGGGCCTGACGTTAACCCGGCTCTGGCACTGGAGCAGAAGCGGGCTGAGGAGGCGGTGGCAGCAGTCATGGTGGCCTCT
TGCCCAAATCACCCCTCCCGAGTCTCCACAGCTGACAACATCTATGTCAACCACAGCTTTGAAGGTTCTATCAAAGGTGCTGGTGCCATC
AGCAACTTCTTGCCCAACAATGGGCGGCAGTTCTGATACAGCCAGAGGCCCTGTCTAGGCTCTATGGCCCTGAACCAAAGGGTTATGGGG
ATCTTCCTTGTGACTGCCCCTTGACACACGCCCTCCTCAAATCCTAGGGGAGGCCATTCCCATGAGACTGCCTGTCACTGGAGGATGGCC
TGCTCTTGAGGTATCCAGGCAGCACCACTGATGGCTCCTCTGCTCCCATAGTGGGTCCCCAGTTTCCAAGTCACCTAGGCCTTGGGCAGT
GCCTCCTCCTGGGCCTGGGTCTGGAAGTTGGCAGGAACAGACACACTCCATGTTTGTCCCACACTCACTCACTTTCCTAGGAGCCCACTT
CTCATCCAACTTTTCCCTTCTCAGTTCCTCTCTCGAAAGTCTTAATTCTGTGTCAGTAAGTCTTTAACACGTAGCAGTGTCCCTGAGAAC
ACAGACAATGACCACTACCCTGGGTGTGATATCACAGGAGGCCAGAGAGAGGCAAAGGCTCAGGCCAAGAGCCAACGCTGTGGGAGGCCG
GTCGGCAGCCACTCCCTCCAGGGCGCACCTGCAGGTCTGCCATCCACGGCCTTTTCTGGCAAGAGAAGGGCCCAGGAAGGATGCTCTCAT
AAGGCCCAGGAAGGATGCTCTCATAAGCACCTTGGTCATGGATTAGCCCCTCCTGGAAAATGGTGTTGGGTTTGGTCTCCAGCTCCAATA
CTTATTAAGGCTGTTGCTGCCAGTCAAGGCCACCCAGGAGTCTGAAGGCTGGGAGCTCTTGGGGCTGGGCTGGTCCTCCCATCTTCACCT
CGGGCCTGGATCCCAGGCCTCAAACCAGCCCAACCCGAGCTTTTGGACAGCTCTCCAGAAGCATGAACTGCAGTGGAGATGAAGATCCTG

>85146_85146_1_SOGA3-NPC1L1_SOGA3_chr6_127796438_ENST00000368268_NPC1L1_chr7_44561841_ENST00000289547_length(amino acids)=1391AA_BP=909
MSQPPIGGAAPATAAASPAAAATEARLHPEGSSRKQQRAQSPARPRDSSLRQTIAATRSPVGAGTKLNSVRQQQLQQQQQQGNKTGSRTG
PPASIRGGGGGAEKATPLAPKGAAPGAVQPVAGAEAAPAATLAALGGRRPGPPEEPPRELESVPSKLGEPPPLGEGGGGGGEGGGAGGGS
GEREGGAPQPPPPRGWRGKGVRAQQRGGSGGEGASPSPSSSSAGKTPGTGSRNSGSGVAGGGSGGGGSYWKEGCLQSELIQFHLKKERAA
AAAAAAQMHAKNGGGSSSRSSPVSGPPAVCETLAVASASPMAAAAEGPQQSAEGSASGGGMQAAAPPSSQPHPQQLQEQEEMQEEMEKLR
EENETLKNEIDELRTEMDEMRDTFFEEDACQLQEMRHELERANKNCRILQYRLRKAERKRLRYAQTGEIDGELLRSLEQDLKVAKDVSVR
LHHELENVEEKRTTTEDENEKLRQQLIEVEIAKQALQNELEKMKELSLKRRGSKDLPKSEKKAQQTPTEEDNEDLKCQLQFVKEEAALMR
KKMAKIDKEKDRFEHELQKYRSFYGDLDSPLPKGEAGGPPSTREAELKLRLRLVEEEANILGRKIVELEVENRGLKAELDDLRGDDFNGS
ANPLMREQSESLSELRQHLQLVEDETELLRRNVADLEEQNKRITAELNKYKYKSGGHDSARHHDNAKTEALQEELKAARLQINELSGKVM
QLQYENRVLMSNMQRYDLASHLGIRGSPRDSDAESDAGKKESDDDSRPPHRKREGPIGGESDSEEVRNIRCLTPTRSFYPAPGPWPKSFS
DRQQMKDIRSEAERLGKTIDRLIADTSTIITEARIYVANGDLFGLMDEEDDGSRIREHELLYRINAQMKAFRKELQTFIDRLEVPKSADD
RGAEEPISVSQDSYLLDYFLFLNRYFEVGAPVYFVTTLGYNFSSEAGMNAICSSAGCNNFSFTQKIQYATEFPEQSYLAIPASSWVDDFI
DWLTPSSCCRLYISGPNKDKFCPSTVNSLNCLKNCMSITMGSVRPSVEQFHKYLPWFLNDRPNIKCPKGGLAAYSTSVNLTSDGQVLDTV
AILSPRLEYSGTISAHCNLYLLDSTSRFMAYHKPLKNSQDYTEALRAARELAANITADLRKVPGTDPAFEVFPYTITNVFYEQYLTILPE
GLFMLSLCLVPTFAVSCLLLGLDLRSGLLNLLSIVMILVDTVGFMALWGISYNAVSLINLVSAVGMSVEFVSHITRSFAISTKPTWLERA
KEATISMGSAVFAGVAMTNLPGILVLGLAKAQLIQIFFFRLNLLITLLGLLHGLVFLPVILSYVGPDVNPALALEQKRAEEAVAAVMVAS

--------------------------------------------------------------
>85146_85146_2_SOGA3-NPC1L1_SOGA3_chr6_127796438_ENST00000481848_NPC1L1_chr7_44561841_ENST00000289547_length(transcript)=5599nt_BP=3244nt
CTCTTTGGTTACTTCTACCCTATCGTCCCTTGCAATCCCGCCTTCTCTCCTGCCCAGTTCGGTGAGGTCAGCTCATGAACATCTCTGCAC
TTCCTGGGGAGCGTCTGGCCCAGCTTGGTACCTCGCGTGTTAGCCTGCTGAGAGCTGCAGCTCCAGCCCAGCCGCGGACCGCCGGGAAGT
CACCCGCTCTGGGGGCAGCTGAATCTTGACGTTACCGCCATTGTTTGGAGAAATCGAGTGGGTGTGGAACTGCGGCGAGCGAGCCCAAAG
TCATGCTCAGCCGGAAAGTCGCATACAATAATATGAAGTTGAACTTTCCTCGGCGCAGAAAGGCACAATAATAAACCCTGAGATCCCCGG
AATATCAGAAGGAAAGTGCTGTTGATTTGTTCAGCTACTTGGAAACCTCGCCTCTGCTGAGAACTTAGGAAGGAAGGTTGGCGGCGGTGA
AGAGGGAAGAGGATGATCTAGTAATGGGCTCTTCCAAATCGCATCTGGTAGGTTCATAGCCATGAGTCAGCCACCAATCGGGGGCGCTGC
CCCTGCCACAGCAGCAGCTTCTCCCGCCGCTGCAGCCACTGAGGCTCGTCTGCACCCGGAGGGCAGCAGCAGAAAGCAGCAGCGAGCTCA
GTCACCCGCTAGACCGAGGGACAGTTCGCTGCGACAGACAATCGCGGCCACCCGGTCCCCAGTGGGGGCCGGCACTAAACTCAATTCTGT
TCGGCAGCAGCAGCTGCAGCAGCAGCAACAGCAGGGTAACAAGACCGGGAGCCGCACGGGGCCGCCCGCCAGCATCCGAGGAGGCGGAGG
TGGGGCCGAGAAGGCGACGCCCCTGGCGCCCAAAGGGGCCGCTCCGGGAGCTGTCCAGCCTGTGGCTGGTGCTGAAGCGGCCCCCGCCGC
GACCCTGGCCGCTTTGGGCGGCAGGAGGCCCGGACCGCCCGAGGAGCCGCCTCGGGAGCTAGAGTCCGTGCCCTCGAAACTCGGGGAACC
CCCTCCGCTCGGAGAAGGGGGAGGAGGGGGCGGGGAAGGAGGAGGAGCCGGCGGCGGCTCCGGGGAAAGGGAGGGGGGCGCTCCGCAGCC
GCCGCCGCCCAGGGGCTGGCGAGGGAAAGGCGTACGCGCTCAGCAGAGGGGCGGCAGCGGCGGGGAGGGGGCCTCCCCTTCTCCATCCTC
CTCTTCTGCGGGCAAAACCCCAGGAACCGGCAGCAGAAACTCCGGAAGCGGCGTTGCGGGGGGCGGCAGCGGTGGTGGAGGGAGCTACTG
GAAAGAAGGATGTCTGCAGTCTGAGCTCATCCAGTTCCATCTCAAGAAGGAGCGGGCGGCAGCGGCGGCGGCCGCGGCTCAGATGCACGC
TAAGAACGGCGGCGGCAGCAGTAGCCGCAGCTCCCCGGTGTCTGGCCCCCCTGCCGTTTGCGAGACCCTGGCCGTCGCCTCCGCCTCCCC
AATGGCGGCGGCGGCGGAGGGCCCCCAGCAGAGCGCAGAGGGCAGCGCGAGCGGCGGGGGCATGCAGGCGGCAGCGCCCCCTTCGTCGCA
GCCGCACCCGCAGCAGCTCCAAGAGCAGGAAGAAATGCAAGAGGAGATGGAGAAGCTGCGAGAGGAAAACGAGACTCTCAAGAACGAGAT
CGATGAGCTGAGAACCGAGATGGACGAGATGAGGGACACTTTCTTCGAGGAGGATGCCTGTCAACTGCAGGAAATGCGCCACGAGTTGGA
GAGAGCCAACAAAAACTGCCGGATCCTGCAGTACCGCCTCCGCAAAGCCGAGCGCAAAAGGCTCCGCTACGCCCAGACCGGGGAAATCGA
CGGGGAGCTGTTGCGCAGCCTGGAGCAGGACCTCAAGGTTGCAAAGGATGTATCTGTGAGACTTCACCATGAATTAGAAAATGTGGAAGA
AAAGAGAACAACAACAGAAGATGAAAATGAGAAACTGAGGCAACAGCTCATAGAAGTTGAAATTGCAAAGCAAGCTTTACAGAATGAACT
GGAAAAAATGAAAGAGTTATCCTTAAAAAGAAGAGGAAGCAAAGATTTGCCAAAATCTGAAAAAAAGGCTCAACAGACTCCCACAGAGGA
GGACAATGAAGATCTGAAGTGCCAGCTGCAGTTTGTTAAGGAAGAAGCCGCTTTGATGAGAAAGAAAATGGCCAAGATTGATAAAGAAAA
GGACAGATTTGAACACGAGCTCCAGAAGTACAGATCCTTTTATGGGGATCTGGACAGTCCTTTGCCCAAAGGAGAAGCCGGAGGCCCTCC
CAGCACTAGGGAGGCCGAGCTCAAGCTACGGCTAAGGCTGGTGGAGGAAGAAGCCAACATCCTGGGCAGGAAAATCGTCGAACTGGAGGT
GGAGAACAGAGGCCTGAAGGCGGAACTGGACGACCTTAGGGGCGATGACTTCAACGGCTCGGCCAACCCGCTCATGAGGGAGCAGAGCGA
ATCCCTGTCGGAGCTGCGGCAGCACCTGCAGCTGGTGGAAGACGAGACGGAGCTGCTGCGGAGGAACGTGGCCGACCTGGAGGAGCAGAA
CAAGCGCATCACGGCGGAGCTCAACAAGTACAAGTACAAGTCCGGCGGCCACGACAGCGCGCGGCACCACGACAACGCCAAGACCGAGGC
CCTGCAGGAGGAGCTGAAGGCGGCGCGCCTGCAGATCAACGAGCTCAGCGGCAAGGTCATGCAGCTGCAGTACGAGAACCGCGTGCTTAT
GTCCAACATGCAGCGCTACGACCTGGCCTCGCACCTGGGCATCCGCGGCAGCCCCCGCGACAGCGACGCCGAGAGCGACGCGGGCAAGAA
GGAGAGCGACGACGACTCGCGGCCTCCGCACCGCAAGCGCGAAGGGCCCATCGGCGGCGAGAGCGACTCGGAGGAGGTGCGCAACATCCG
CTGCCTCACGCCCACTCGCTCCTTCTACCCGGCGCCCGGGCCCTGGCCCAAGAGCTTCTCCGATCGGCAGCAGATGAAGGACATCCGCTC
GGAGGCCGAGCGCCTGGGCAAGACCATCGACCGGCTCATCGCCGACACGAGCACCATCATCACCGAGGCGCGCATCTACGTGGCCAACGG
GGACCTGTTCGGACTCATGGACGAGGAGGACGACGGCAGCCGCATCCGGGAGCACGAGCTGCTCTACCGCATCAACGCTCAGATGAAGGC
CTTCCGCAAGGAGCTGCAGACCTTCATCGACCGCCTCGAGGTGCCCAAGTCTGCGGACGACCGCGGCGCCGAGGAGCCCATTTCCGTGAG
TCAGGACTCGTACCTGCTTGACTATTTCCTCTTTCTGAACCGCTACTTCGAGGTGGGGGCCCCGGTGTACTTTGTTACCACCTTGGGCTA
CAACTTCTCCAGCGAGGCTGGGATGAATGCCATCTGCTCCAGTGCAGGCTGCAACAACTTCTCCTTCACCCAGAAGATCCAGTATGCCAC
AGAGTTCCCTGAGCAGTCTTACCTGGCCATCCCTGCCTCCTCCTGGGTGGATGACTTCATTGACTGGCTGACCCCGTCCTCCTGCTGCCG
CCTTTATATATCTGGCCCCAATAAGGACAAGTTCTGCCCCTCGACCGTCAACTCTCTGAACTGCCTAAAGAACTGCATGAGCATCACGAT
GGGCTCTGTGAGGCCCTCGGTGGAGCAGTTCCATAAGTATCTTCCCTGGTTCCTGAACGACCGGCCCAACATCAAATGTCCCAAAGGCGG
CCTGGCAGCATACAGCACCTCTGTGAACTTGACTTCAGATGGCCAGGTTTTAGACACAGTTGCCATTCTGTCACCCAGGCTGGAGTACAG
TGGCACAATCTCGGCTCACTGCAACCTCTACCTCCTGGATTCAACCTCCAGGTTCATGGCCTATCACAAGCCCCTGAAAAACTCACAGGA
TTACACAGAAGCTCTGCGGGCAGCTCGAGAGCTGGCAGCCAACATCACTGCTGACCTGCGGAAAGTGCCTGGAACAGACCCGGCTTTTGA
GGTCTTCCCCTACACGATCACCAATGTGTTTTATGAGCAGTACCTGACCATCCTCCCTGAGGGGCTCTTCATGCTCAGCCTCTGCCTTGT
GCCCACCTTCGCTGTCTCCTGCCTCCTGCTGGGCCTGGACCTGCGCTCCGGCCTCCTCAACCTGCTCTCCATTGTCATGATCCTCGTGGA
CACTGTCGGCTTCATGGCCCTGTGGGGCATCAGTTACAATGCTGTGTCCCTCATCAACCTGGTCTCGGCGGTGGGCATGTCTGTGGAGTT
TGTGTCCCACATTACCCGCTCCTTTGCCATCAGCACCAAGCCCACCTGGCTGGAGAGGGCCAAAGAGGCCACCATCTCTATGGGAAGTGC
GGTGTTTGCAGGTGTGGCCATGACCAACCTGCCTGGCATCCTTGTCCTGGGCCTCGCCAAGGCCCAGCTCATTCAGATCTTCTTCTTCCG
CCTCAACCTCCTGATCACTCTGCTGGGCCTGCTGCATGGCTTGGTCTTCCTGCCCGTCATCCTCAGCTACGTGGGGCCTGACGTTAACCC
GGCTCTGGCACTGGAGCAGAAGCGGGCTGAGGAGGCGGTGGCAGCAGTCATGGTGGCCTCTTGCCCAAATCACCCCTCCCGAGTCTCCAC
AGCTGACAACATCTATGTCAACCACAGCTTTGAAGGTTCTATCAAAGGTGCTGGTGCCATCAGCAACTTCTTGCCCAACAATGGGCGGCA
GTTCTGATACAGCCAGAGGCCCTGTCTAGGCTCTATGGCCCTGAACCAAAGGGTTATGGGGATCTTCCTTGTGACTGCCCCTTGACACAC
GCCCTCCTCAAATCCTAGGGGAGGCCATTCCCATGAGACTGCCTGTCACTGGAGGATGGCCTGCTCTTGAGGTATCCAGGCAGCACCACT
GATGGCTCCTCTGCTCCCATAGTGGGTCCCCAGTTTCCAAGTCACCTAGGCCTTGGGCAGTGCCTCCTCCTGGGCCTGGGTCTGGAAGTT
GGCAGGAACAGACACACTCCATGTTTGTCCCACACTCACTCACTTTCCTAGGAGCCCACTTCTCATCCAACTTTTCCCTTCTCAGTTCCT
CTCTCGAAAGTCTTAATTCTGTGTCAGTAAGTCTTTAACACGTAGCAGTGTCCCTGAGAACACAGACAATGACCACTACCCTGGGTGTGA
TATCACAGGAGGCCAGAGAGAGGCAAAGGCTCAGGCCAAGAGCCAACGCTGTGGGAGGCCGGTCGGCAGCCACTCCCTCCAGGGCGCACC
TGCAGGTCTGCCATCCACGGCCTTTTCTGGCAAGAGAAGGGCCCAGGAAGGATGCTCTCATAAGGCCCAGGAAGGATGCTCTCATAAGCA
CCTTGGTCATGGATTAGCCCCTCCTGGAAAATGGTGTTGGGTTTGGTCTCCAGCTCCAATACTTATTAAGGCTGTTGCTGCCAGTCAAGG
CCACCCAGGAGTCTGAAGGCTGGGAGCTCTTGGGGCTGGGCTGGTCCTCCCATCTTCACCTCGGGCCTGGATCCCAGGCCTCAAACCAGC
CCAACCCGAGCTTTTGGACAGCTCTCCAGAAGCATGAACTGCAGTGGAGATGAAGATCCTGGCTCTGTGCTGTGCACATAGGTGTTTAAT

>85146_85146_2_SOGA3-NPC1L1_SOGA3_chr6_127796438_ENST00000481848_NPC1L1_chr7_44561841_ENST00000289547_length(amino acids)=1391AA_BP=909
MSQPPIGGAAPATAAASPAAAATEARLHPEGSSRKQQRAQSPARPRDSSLRQTIAATRSPVGAGTKLNSVRQQQLQQQQQQGNKTGSRTG
PPASIRGGGGGAEKATPLAPKGAAPGAVQPVAGAEAAPAATLAALGGRRPGPPEEPPRELESVPSKLGEPPPLGEGGGGGGEGGGAGGGS
GEREGGAPQPPPPRGWRGKGVRAQQRGGSGGEGASPSPSSSSAGKTPGTGSRNSGSGVAGGGSGGGGSYWKEGCLQSELIQFHLKKERAA
AAAAAAQMHAKNGGGSSSRSSPVSGPPAVCETLAVASASPMAAAAEGPQQSAEGSASGGGMQAAAPPSSQPHPQQLQEQEEMQEEMEKLR
EENETLKNEIDELRTEMDEMRDTFFEEDACQLQEMRHELERANKNCRILQYRLRKAERKRLRYAQTGEIDGELLRSLEQDLKVAKDVSVR
LHHELENVEEKRTTTEDENEKLRQQLIEVEIAKQALQNELEKMKELSLKRRGSKDLPKSEKKAQQTPTEEDNEDLKCQLQFVKEEAALMR
KKMAKIDKEKDRFEHELQKYRSFYGDLDSPLPKGEAGGPPSTREAELKLRLRLVEEEANILGRKIVELEVENRGLKAELDDLRGDDFNGS
ANPLMREQSESLSELRQHLQLVEDETELLRRNVADLEEQNKRITAELNKYKYKSGGHDSARHHDNAKTEALQEELKAARLQINELSGKVM
QLQYENRVLMSNMQRYDLASHLGIRGSPRDSDAESDAGKKESDDDSRPPHRKREGPIGGESDSEEVRNIRCLTPTRSFYPAPGPWPKSFS
DRQQMKDIRSEAERLGKTIDRLIADTSTIITEARIYVANGDLFGLMDEEDDGSRIREHELLYRINAQMKAFRKELQTFIDRLEVPKSADD
RGAEEPISVSQDSYLLDYFLFLNRYFEVGAPVYFVTTLGYNFSSEAGMNAICSSAGCNNFSFTQKIQYATEFPEQSYLAIPASSWVDDFI
DWLTPSSCCRLYISGPNKDKFCPSTVNSLNCLKNCMSITMGSVRPSVEQFHKYLPWFLNDRPNIKCPKGGLAAYSTSVNLTSDGQVLDTV
AILSPRLEYSGTISAHCNLYLLDSTSRFMAYHKPLKNSQDYTEALRAARELAANITADLRKVPGTDPAFEVFPYTITNVFYEQYLTILPE
GLFMLSLCLVPTFAVSCLLLGLDLRSGLLNLLSIVMILVDTVGFMALWGISYNAVSLINLVSAVGMSVEFVSHITRSFAISTKPTWLERA
KEATISMGSAVFAGVAMTNLPGILVLGLAKAQLIQIFFFRLNLLITLLGLLHGLVFLPVILSYVGPDVNPALALEQKRAEEAVAAVMVAS

--------------------------------------------------------------
>85146_85146_3_SOGA3-NPC1L1_SOGA3_chr6_127796438_ENST00000556132_NPC1L1_chr7_44561841_ENST00000289547_length(transcript)=5953nt_BP=3598nt
AGTGAACAAAGAGAACTCCCAGCAGCCGCCAGCCAGCTGCATCAGGAGATGTTAGTCACGCCCGGAAGGCTGTTCTAGTCCGCCTCCTTG
GAAAAGAAGCTCAAGTAAATAATTGATGGAGAATGACCGAACCCAGGACAAAGCTTTGCAGGAAACCAGTGCATCCGTGTTCGAGCGGTT
TTGGGATCCTCTGCCAAGTACGGGATAAGAGAATAGAGCAAGGAGTTTGAGCGCTGCTGCCAATCTTCCATCTCGGGCGTGGCTCTGGCC
TTTTTGTCTCTTTATCCCGCCACTCCCCACCCCCGTCCCCCGTCCCCCTCCCCGCCTTCTTCTCTTTCCTCTTGAAAGTAACCTCTCTTT
GGTTACTTCTACCCTATCGTCCCTTGCAATCCCGCCTTCTCTCCTGCCCAGTTCGGTGAGGTCAGCTCATGAACATCTCTGCACTTCCTG
GGGAGCGTCTGGCCCAGCTTGGTACCTCGCGTGTTAGCCTGCTGAGAGCTGCAGCTCCAGCCCAGCCGCGGACCGCCGGGAAGTCACCCG
CTCTGGGGGCAGCTGAATCTTGACGTTACCGCCATTGTTTGGAGAAATCGAGTGGGTGTGGAACTGCGGCGAGCGAGCCCAAAGTCATGC
TCAGCCGGAAAGTCGCATACAATAATATGAAGTTGAACTTTCCTCGGCGCAGAAAGGCACAATAATAAACCCTGAGATCCCCGGAATATC
AGAAGGAAAGTGCTGTTGATTTGTTCAGCTACTTGGAAACCTCGCCTCTGCTGAGAACTTAGGAAGGAAGGTTGGCGGCGGTGAAGAGGG
AAGAGGATGATCTAGTAATGGGCTCTTCCAAATCGCATCTGGTAGGTTCATAGCCATGAGTCAGCCACCAATCGGGGGCGCTGCCCCTGC
CACAGCAGCAGCTTCTCCCGCCGCTGCAGCCACTGAGGCTCGTCTGCACCCGGAGGGCAGCAGCAGAAAGCAGCAGCGAGCTCAGTCACC
CGCTAGACCGAGGGACAGTTCGCTGCGACAGACAATCGCGGCCACCCGGTCCCCAGTGGGGGCCGGCACTAAACTCAATTCTGTTCGGCA
GCAGCAGCTGCAGCAGCAGCAACAGCAGGGTAACAAGACCGGGAGCCGCACGGGGCCGCCCGCCAGCATCCGAGGAGGCGGAGGTGGGGC
CGAGAAGGCGACGCCCCTGGCGCCCAAAGGGGCCGCTCCGGGAGCTGTCCAGCCTGTGGCTGGTGCTGAAGCGGCCCCCGCCGCGACCCT
GGCCGCTTTGGGCGGCAGGAGGCCCGGACCGCCCGAGGAGCCGCCTCGGGAGCTAGAGTCCGTGCCCTCGAAACTCGGGGAACCCCCTCC
GCTCGGAGAAGGGGGAGGAGGGGGCGGGGAAGGAGGAGGAGCCGGCGGCGGCTCCGGGGAAAGGGAGGGGGGCGCTCCGCAGCCGCCGCC
GCCCAGGGGCTGGCGAGGGAAAGGCGTACGCGCTCAGCAGAGGGGCGGCAGCGGCGGGGAGGGGGCCTCCCCTTCTCCATCCTCCTCTTC
TGCGGGCAAAACCCCAGGAACCGGCAGCAGAAACTCCGGAAGCGGCGTTGCGGGGGGCGGCAGCGGTGGTGGAGGGAGCTACTGGAAAGA
AGGATGTCTGCAGTCTGAGCTCATCCAGTTCCATCTCAAGAAGGAGCGGGCGGCAGCGGCGGCGGCCGCGGCTCAGATGCACGCTAAGAA
CGGCGGCGGCAGCAGTAGCCGCAGCTCCCCGGTGTCTGGCCCCCCTGCCGTTTGCGAGACCCTGGCCGTCGCCTCCGCCTCCCCAATGGC
GGCGGCGGCGGAGGGCCCCCAGCAGAGCGCAGAGGGCAGCGCGAGCGGCGGGGGCATGCAGGCGGCAGCGCCCCCTTCGTCGCAGCCGCA
CCCGCAGCAGCTCCAAGAGCAGGAAGAAATGCAAGAGGAGATGGAGAAGCTGCGAGAGGAAAACGAGACTCTCAAGAACGAGATCGATGA
GCTGAGAACCGAGATGGACGAGATGAGGGACACTTTCTTCGAGGAGGATGCCTGTCAACTGCAGGAAATGCGCCACGAGTTGGAGAGAGC
CAACAAAAACTGCCGGATCCTGCAGTACCGCCTCCGCAAAGCCGAGCGCAAAAGGCTCCGCTACGCCCAGACCGGGGAAATCGACGGGGA
GCTGTTGCGCAGCCTGGAGCAGGACCTCAAGGTTGCAAAGGATGTATCTGTGAGACTTCACCATGAATTAGAAAATGTGGAAGAAAAGAG
AACAACAACAGAAGATGAAAATGAGAAACTGAGGCAACAGCTCATAGAAGTTGAAATTGCAAAGCAAGCTTTACAGAATGAACTGGAAAA
AATGAAAGAGTTATCCTTAAAAAGAAGAGGAAGCAAAGATTTGCCAAAATCTGAAAAAAAGGCTCAACAGACTCCCACAGAGGAGGACAA
TGAAGATCTGAAGTGCCAGCTGCAGTTTGTTAAGGAAGAAGCCGCTTTGATGAGAAAGAAAATGGCCAAGATTGATAAAGAAAAGGACAG
ATTTGAACACGAGCTCCAGAAGTACAGATCCTTTTATGGGGATCTGGACAGTCCTTTGCCCAAAGGAGAAGCCGGAGGCCCTCCCAGCAC
TAGGGAGGCCGAGCTCAAGCTACGGCTAAGGCTGGTGGAGGAAGAAGCCAACATCCTGGGCAGGAAAATCGTCGAACTGGAGGTGGAGAA
CAGAGGCCTGAAGGCGGAACTGGACGACCTTAGGGGCGATGACTTCAACGGCTCGGCCAACCCGCTCATGAGGGAGCAGAGCGAATCCCT
GTCGGAGCTGCGGCAGCACCTGCAGCTGGTGGAAGACGAGACGGAGCTGCTGCGGAGGAACGTGGCCGACCTGGAGGAGCAGAACAAGCG
CATCACGGCGGAGCTCAACAAGTACAAGTACAAGTCCGGCGGCCACGACAGCGCGCGGCACCACGACAACGCCAAGACCGAGGCCCTGCA
GGAGGAGCTGAAGGCGGCGCGCCTGCAGATCAACGAGCTCAGCGGCAAGGTCATGCAGCTGCAGTACGAGAACCGCGTGCTTATGTCCAA
CATGCAGCGCTACGACCTGGCCTCGCACCTGGGCATCCGCGGCAGCCCCCGCGACAGCGACGCCGAGAGCGACGCGGGCAAGAAGGAGAG
CGACGACGACTCGCGGCCTCCGCACCGCAAGCGCGAAGGGCCCATCGGCGGCGAGAGCGACTCGGAGGAGGTGCGCAACATCCGCTGCCT
CACGCCCACTCGCTCCTTCTACCCGGCGCCCGGGCCCTGGCCCAAGAGCTTCTCCGATCGGCAGCAGATGAAGGACATCCGCTCGGAGGC
CGAGCGCCTGGGCAAGACCATCGACCGGCTCATCGCCGACACGAGCACCATCATCACCGAGGCGCGCATCTACGTGGCCAACGGGGACCT
GTTCGGACTCATGGACGAGGAGGACGACGGCAGCCGCATCCGGGAGCACGAGCTGCTCTACCGCATCAACGCTCAGATGAAGGCCTTCCG
CAAGGAGCTGCAGACCTTCATCGACCGCCTCGAGGTGCCCAAGTCTGCGGACGACCGCGGCGCCGAGGAGCCCATTTCCGTGAGTCAGGA
CTCGTACCTGCTTGACTATTTCCTCTTTCTGAACCGCTACTTCGAGGTGGGGGCCCCGGTGTACTTTGTTACCACCTTGGGCTACAACTT
CTCCAGCGAGGCTGGGATGAATGCCATCTGCTCCAGTGCAGGCTGCAACAACTTCTCCTTCACCCAGAAGATCCAGTATGCCACAGAGTT
CCCTGAGCAGTCTTACCTGGCCATCCCTGCCTCCTCCTGGGTGGATGACTTCATTGACTGGCTGACCCCGTCCTCCTGCTGCCGCCTTTA
TATATCTGGCCCCAATAAGGACAAGTTCTGCCCCTCGACCGTCAACTCTCTGAACTGCCTAAAGAACTGCATGAGCATCACGATGGGCTC
TGTGAGGCCCTCGGTGGAGCAGTTCCATAAGTATCTTCCCTGGTTCCTGAACGACCGGCCCAACATCAAATGTCCCAAAGGCGGCCTGGC
AGCATACAGCACCTCTGTGAACTTGACTTCAGATGGCCAGGTTTTAGACACAGTTGCCATTCTGTCACCCAGGCTGGAGTACAGTGGCAC
AATCTCGGCTCACTGCAACCTCTACCTCCTGGATTCAACCTCCAGGTTCATGGCCTATCACAAGCCCCTGAAAAACTCACAGGATTACAC
AGAAGCTCTGCGGGCAGCTCGAGAGCTGGCAGCCAACATCACTGCTGACCTGCGGAAAGTGCCTGGAACAGACCCGGCTTTTGAGGTCTT
CCCCTACACGATCACCAATGTGTTTTATGAGCAGTACCTGACCATCCTCCCTGAGGGGCTCTTCATGCTCAGCCTCTGCCTTGTGCCCAC
CTTCGCTGTCTCCTGCCTCCTGCTGGGCCTGGACCTGCGCTCCGGCCTCCTCAACCTGCTCTCCATTGTCATGATCCTCGTGGACACTGT
CGGCTTCATGGCCCTGTGGGGCATCAGTTACAATGCTGTGTCCCTCATCAACCTGGTCTCGGCGGTGGGCATGTCTGTGGAGTTTGTGTC
CCACATTACCCGCTCCTTTGCCATCAGCACCAAGCCCACCTGGCTGGAGAGGGCCAAAGAGGCCACCATCTCTATGGGAAGTGCGGTGTT
TGCAGGTGTGGCCATGACCAACCTGCCTGGCATCCTTGTCCTGGGCCTCGCCAAGGCCCAGCTCATTCAGATCTTCTTCTTCCGCCTCAA
CCTCCTGATCACTCTGCTGGGCCTGCTGCATGGCTTGGTCTTCCTGCCCGTCATCCTCAGCTACGTGGGGCCTGACGTTAACCCGGCTCT
GGCACTGGAGCAGAAGCGGGCTGAGGAGGCGGTGGCAGCAGTCATGGTGGCCTCTTGCCCAAATCACCCCTCCCGAGTCTCCACAGCTGA
CAACATCTATGTCAACCACAGCTTTGAAGGTTCTATCAAAGGTGCTGGTGCCATCAGCAACTTCTTGCCCAACAATGGGCGGCAGTTCTG
ATACAGCCAGAGGCCCTGTCTAGGCTCTATGGCCCTGAACCAAAGGGTTATGGGGATCTTCCTTGTGACTGCCCCTTGACACACGCCCTC
CTCAAATCCTAGGGGAGGCCATTCCCATGAGACTGCCTGTCACTGGAGGATGGCCTGCTCTTGAGGTATCCAGGCAGCACCACTGATGGC
TCCTCTGCTCCCATAGTGGGTCCCCAGTTTCCAAGTCACCTAGGCCTTGGGCAGTGCCTCCTCCTGGGCCTGGGTCTGGAAGTTGGCAGG
AACAGACACACTCCATGTTTGTCCCACACTCACTCACTTTCCTAGGAGCCCACTTCTCATCCAACTTTTCCCTTCTCAGTTCCTCTCTCG
AAAGTCTTAATTCTGTGTCAGTAAGTCTTTAACACGTAGCAGTGTCCCTGAGAACACAGACAATGACCACTACCCTGGGTGTGATATCAC
AGGAGGCCAGAGAGAGGCAAAGGCTCAGGCCAAGAGCCAACGCTGTGGGAGGCCGGTCGGCAGCCACTCCCTCCAGGGCGCACCTGCAGG
TCTGCCATCCACGGCCTTTTCTGGCAAGAGAAGGGCCCAGGAAGGATGCTCTCATAAGGCCCAGGAAGGATGCTCTCATAAGCACCTTGG
TCATGGATTAGCCCCTCCTGGAAAATGGTGTTGGGTTTGGTCTCCAGCTCCAATACTTATTAAGGCTGTTGCTGCCAGTCAAGGCCACCC
AGGAGTCTGAAGGCTGGGAGCTCTTGGGGCTGGGCTGGTCCTCCCATCTTCACCTCGGGCCTGGATCCCAGGCCTCAAACCAGCCCAACC
CGAGCTTTTGGACAGCTCTCCAGAAGCATGAACTGCAGTGGAGATGAAGATCCTGGCTCTGTGCTGTGCACATAGGTGTTTAATAAACAT

>85146_85146_3_SOGA3-NPC1L1_SOGA3_chr6_127796438_ENST00000556132_NPC1L1_chr7_44561841_ENST00000289547_length(amino acids)=1391AA_BP=909
MSQPPIGGAAPATAAASPAAAATEARLHPEGSSRKQQRAQSPARPRDSSLRQTIAATRSPVGAGTKLNSVRQQQLQQQQQQGNKTGSRTG
PPASIRGGGGGAEKATPLAPKGAAPGAVQPVAGAEAAPAATLAALGGRRPGPPEEPPRELESVPSKLGEPPPLGEGGGGGGEGGGAGGGS
GEREGGAPQPPPPRGWRGKGVRAQQRGGSGGEGASPSPSSSSAGKTPGTGSRNSGSGVAGGGSGGGGSYWKEGCLQSELIQFHLKKERAA
AAAAAAQMHAKNGGGSSSRSSPVSGPPAVCETLAVASASPMAAAAEGPQQSAEGSASGGGMQAAAPPSSQPHPQQLQEQEEMQEEMEKLR
EENETLKNEIDELRTEMDEMRDTFFEEDACQLQEMRHELERANKNCRILQYRLRKAERKRLRYAQTGEIDGELLRSLEQDLKVAKDVSVR
LHHELENVEEKRTTTEDENEKLRQQLIEVEIAKQALQNELEKMKELSLKRRGSKDLPKSEKKAQQTPTEEDNEDLKCQLQFVKEEAALMR
KKMAKIDKEKDRFEHELQKYRSFYGDLDSPLPKGEAGGPPSTREAELKLRLRLVEEEANILGRKIVELEVENRGLKAELDDLRGDDFNGS
ANPLMREQSESLSELRQHLQLVEDETELLRRNVADLEEQNKRITAELNKYKYKSGGHDSARHHDNAKTEALQEELKAARLQINELSGKVM
QLQYENRVLMSNMQRYDLASHLGIRGSPRDSDAESDAGKKESDDDSRPPHRKREGPIGGESDSEEVRNIRCLTPTRSFYPAPGPWPKSFS
DRQQMKDIRSEAERLGKTIDRLIADTSTIITEARIYVANGDLFGLMDEEDDGSRIREHELLYRINAQMKAFRKELQTFIDRLEVPKSADD
RGAEEPISVSQDSYLLDYFLFLNRYFEVGAPVYFVTTLGYNFSSEAGMNAICSSAGCNNFSFTQKIQYATEFPEQSYLAIPASSWVDDFI
DWLTPSSCCRLYISGPNKDKFCPSTVNSLNCLKNCMSITMGSVRPSVEQFHKYLPWFLNDRPNIKCPKGGLAAYSTSVNLTSDGQVLDTV
AILSPRLEYSGTISAHCNLYLLDSTSRFMAYHKPLKNSQDYTEALRAARELAANITADLRKVPGTDPAFEVFPYTITNVFYEQYLTILPE
GLFMLSLCLVPTFAVSCLLLGLDLRSGLLNLLSIVMILVDTVGFMALWGISYNAVSLINLVSAVGMSVEFVSHITRSFAISTKPTWLERA
KEATISMGSAVFAGVAMTNLPGILVLGLAKAQLIQIFFFRLNLLITLLGLLHGLVFLPVILSYVGPDVNPALALEQKRAEEAVAAVMVAS

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Fusion Gene PPI Analysis for SOGA3-NPC1L1


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for SOGA3-NPC1L1


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for SOGA3-NPC1L1


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource