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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:SORBS2-OS9 (FusionGDB2 ID:85192)

Fusion Gene Summary for SORBS2-OS9

check button Fusion gene summary
Fusion gene informationFusion gene name: SORBS2-OS9
Fusion gene ID: 85192
HgeneTgene
Gene symbol

SORBS2

OS9

Gene ID

8470

10956

Gene namesorbin and SH3 domain containing 2OS9 endoplasmic reticulum lectin
SynonymsARGBP2|PRO0618ERLEC2|OS-9
Cytomap

4q35.1

12q13.3-q14.1

Type of geneprotein-codingprotein-coding
Descriptionsorbin and SH3 domain-containing protein 2Arg binding protein 2Arg/Abl-interacting protein 2arg-binding protein 2protein OS-9amplified in osteosarcoma 9endoplasmic reticulum lectin 2erlectin 2osteosarcoma amplified 9, endoplasmic reticulum associated proteinosteosarcoma amplified 9, endoplasmic reticulum lectin
Modification date2020031320200313
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000284776, ENST00000319471, 
ENST00000355634, ENST00000393528, 
ENST00000431808, ENST00000437304, 
ENST00000448662, ENST00000449407, 
ENST00000418609, ENST00000498125, 
ENST00000257966, ENST00000389142, 
ENST00000413095, ENST00000435406, 
ENST00000551035, ENST00000315970, 
ENST00000389146, ENST00000439210, 
ENST00000552285, 
Fusion gene scores* DoF score16 X 20 X 8=256028 X 16 X 12=5376
# samples 2138
** MAII scorelog2(21/2560*10)=-3.60768257722124
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(38/5376*10)=-3.82246181444781
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: SORBS2 [Title/Abstract] AND OS9 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointSORBS2(186578578)-OS9(58109543), # samples:2
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
TgeneOS9

GO:0006621

protein retention in ER lumen

18417469

TgeneOS9

GO:0034976

response to endoplasmic reticulum stress

19084021


check buttonFusion gene breakpoints across SORBS2 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across OS9 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4GBMTCGA-06-0178-01ASORBS2chr4

186578578

-OS9chr12

58109543

+


Top

Fusion Gene ORF analysis for SORBS2-OS9

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000284776ENST00000257966SORBS2chr4

186578578

-OS9chr12

58109543

+
5CDS-intronENST00000284776ENST00000389142SORBS2chr4

186578578

-OS9chr12

58109543

+
5CDS-intronENST00000284776ENST00000413095SORBS2chr4

186578578

-OS9chr12

58109543

+
5CDS-intronENST00000284776ENST00000435406SORBS2chr4

186578578

-OS9chr12

58109543

+
5CDS-intronENST00000284776ENST00000551035SORBS2chr4

186578578

-OS9chr12

58109543

+
5CDS-intronENST00000319471ENST00000257966SORBS2chr4

186578578

-OS9chr12

58109543

+
5CDS-intronENST00000319471ENST00000389142SORBS2chr4

186578578

-OS9chr12

58109543

+
5CDS-intronENST00000319471ENST00000413095SORBS2chr4

186578578

-OS9chr12

58109543

+
5CDS-intronENST00000319471ENST00000435406SORBS2chr4

186578578

-OS9chr12

58109543

+
5CDS-intronENST00000319471ENST00000551035SORBS2chr4

186578578

-OS9chr12

58109543

+
5CDS-intronENST00000355634ENST00000257966SORBS2chr4

186578578

-OS9chr12

58109543

+
5CDS-intronENST00000355634ENST00000389142SORBS2chr4

186578578

-OS9chr12

58109543

+
5CDS-intronENST00000355634ENST00000413095SORBS2chr4

186578578

-OS9chr12

58109543

+
5CDS-intronENST00000355634ENST00000435406SORBS2chr4

186578578

-OS9chr12

58109543

+
5CDS-intronENST00000355634ENST00000551035SORBS2chr4

186578578

-OS9chr12

58109543

+
5CDS-intronENST00000393528ENST00000257966SORBS2chr4

186578578

-OS9chr12

58109543

+
5CDS-intronENST00000393528ENST00000389142SORBS2chr4

186578578

-OS9chr12

58109543

+
5CDS-intronENST00000393528ENST00000413095SORBS2chr4

186578578

-OS9chr12

58109543

+
5CDS-intronENST00000393528ENST00000435406SORBS2chr4

186578578

-OS9chr12

58109543

+
5CDS-intronENST00000393528ENST00000551035SORBS2chr4

186578578

-OS9chr12

58109543

+
5CDS-intronENST00000431808ENST00000257966SORBS2chr4

186578578

-OS9chr12

58109543

+
5CDS-intronENST00000431808ENST00000389142SORBS2chr4

186578578

-OS9chr12

58109543

+
5CDS-intronENST00000431808ENST00000413095SORBS2chr4

186578578

-OS9chr12

58109543

+
5CDS-intronENST00000431808ENST00000435406SORBS2chr4

186578578

-OS9chr12

58109543

+
5CDS-intronENST00000431808ENST00000551035SORBS2chr4

186578578

-OS9chr12

58109543

+
5CDS-intronENST00000437304ENST00000257966SORBS2chr4

186578578

-OS9chr12

58109543

+
5CDS-intronENST00000437304ENST00000389142SORBS2chr4

186578578

-OS9chr12

58109543

+
5CDS-intronENST00000437304ENST00000413095SORBS2chr4

186578578

-OS9chr12

58109543

+
5CDS-intronENST00000437304ENST00000435406SORBS2chr4

186578578

-OS9chr12

58109543

+
5CDS-intronENST00000437304ENST00000551035SORBS2chr4

186578578

-OS9chr12

58109543

+
5CDS-intronENST00000448662ENST00000257966SORBS2chr4

186578578

-OS9chr12

58109543

+
5CDS-intronENST00000448662ENST00000389142SORBS2chr4

186578578

-OS9chr12

58109543

+
5CDS-intronENST00000448662ENST00000413095SORBS2chr4

186578578

-OS9chr12

58109543

+
5CDS-intronENST00000448662ENST00000435406SORBS2chr4

186578578

-OS9chr12

58109543

+
5CDS-intronENST00000448662ENST00000551035SORBS2chr4

186578578

-OS9chr12

58109543

+
5CDS-intronENST00000449407ENST00000257966SORBS2chr4

186578578

-OS9chr12

58109543

+
5CDS-intronENST00000449407ENST00000389142SORBS2chr4

186578578

-OS9chr12

58109543

+
5CDS-intronENST00000449407ENST00000413095SORBS2chr4

186578578

-OS9chr12

58109543

+
5CDS-intronENST00000449407ENST00000435406SORBS2chr4

186578578

-OS9chr12

58109543

+
5CDS-intronENST00000449407ENST00000551035SORBS2chr4

186578578

-OS9chr12

58109543

+
Frame-shiftENST00000319471ENST00000315970SORBS2chr4

186578578

-OS9chr12

58109543

+
Frame-shiftENST00000319471ENST00000389146SORBS2chr4

186578578

-OS9chr12

58109543

+
Frame-shiftENST00000319471ENST00000439210SORBS2chr4

186578578

-OS9chr12

58109543

+
Frame-shiftENST00000319471ENST00000552285SORBS2chr4

186578578

-OS9chr12

58109543

+
Frame-shiftENST00000355634ENST00000315970SORBS2chr4

186578578

-OS9chr12

58109543

+
Frame-shiftENST00000355634ENST00000389146SORBS2chr4

186578578

-OS9chr12

58109543

+
Frame-shiftENST00000355634ENST00000439210SORBS2chr4

186578578

-OS9chr12

58109543

+
Frame-shiftENST00000355634ENST00000552285SORBS2chr4

186578578

-OS9chr12

58109543

+
Frame-shiftENST00000431808ENST00000315970SORBS2chr4

186578578

-OS9chr12

58109543

+
Frame-shiftENST00000431808ENST00000389146SORBS2chr4

186578578

-OS9chr12

58109543

+
Frame-shiftENST00000431808ENST00000439210SORBS2chr4

186578578

-OS9chr12

58109543

+
Frame-shiftENST00000431808ENST00000552285SORBS2chr4

186578578

-OS9chr12

58109543

+
Frame-shiftENST00000437304ENST00000315970SORBS2chr4

186578578

-OS9chr12

58109543

+
Frame-shiftENST00000437304ENST00000389146SORBS2chr4

186578578

-OS9chr12

58109543

+
Frame-shiftENST00000437304ENST00000439210SORBS2chr4

186578578

-OS9chr12

58109543

+
Frame-shiftENST00000437304ENST00000552285SORBS2chr4

186578578

-OS9chr12

58109543

+
Frame-shiftENST00000448662ENST00000315970SORBS2chr4

186578578

-OS9chr12

58109543

+
Frame-shiftENST00000448662ENST00000389146SORBS2chr4

186578578

-OS9chr12

58109543

+
Frame-shiftENST00000448662ENST00000439210SORBS2chr4

186578578

-OS9chr12

58109543

+
Frame-shiftENST00000448662ENST00000552285SORBS2chr4

186578578

-OS9chr12

58109543

+
Frame-shiftENST00000449407ENST00000315970SORBS2chr4

186578578

-OS9chr12

58109543

+
Frame-shiftENST00000449407ENST00000389146SORBS2chr4

186578578

-OS9chr12

58109543

+
Frame-shiftENST00000449407ENST00000439210SORBS2chr4

186578578

-OS9chr12

58109543

+
Frame-shiftENST00000449407ENST00000552285SORBS2chr4

186578578

-OS9chr12

58109543

+
In-frameENST00000284776ENST00000315970SORBS2chr4

186578578

-OS9chr12

58109543

+
In-frameENST00000284776ENST00000389146SORBS2chr4

186578578

-OS9chr12

58109543

+
In-frameENST00000284776ENST00000439210SORBS2chr4

186578578

-OS9chr12

58109543

+
In-frameENST00000284776ENST00000552285SORBS2chr4

186578578

-OS9chr12

58109543

+
In-frameENST00000393528ENST00000315970SORBS2chr4

186578578

-OS9chr12

58109543

+
In-frameENST00000393528ENST00000389146SORBS2chr4

186578578

-OS9chr12

58109543

+
In-frameENST00000393528ENST00000439210SORBS2chr4

186578578

-OS9chr12

58109543

+
In-frameENST00000393528ENST00000552285SORBS2chr4

186578578

-OS9chr12

58109543

+
intron-3CDSENST00000418609ENST00000315970SORBS2chr4

186578578

-OS9chr12

58109543

+
intron-3CDSENST00000418609ENST00000389146SORBS2chr4

186578578

-OS9chr12

58109543

+
intron-3CDSENST00000418609ENST00000439210SORBS2chr4

186578578

-OS9chr12

58109543

+
intron-3CDSENST00000418609ENST00000552285SORBS2chr4

186578578

-OS9chr12

58109543

+
intron-3CDSENST00000498125ENST00000315970SORBS2chr4

186578578

-OS9chr12

58109543

+
intron-3CDSENST00000498125ENST00000389146SORBS2chr4

186578578

-OS9chr12

58109543

+
intron-3CDSENST00000498125ENST00000439210SORBS2chr4

186578578

-OS9chr12

58109543

+
intron-3CDSENST00000498125ENST00000552285SORBS2chr4

186578578

-OS9chr12

58109543

+
intron-intronENST00000418609ENST00000257966SORBS2chr4

186578578

-OS9chr12

58109543

+
intron-intronENST00000418609ENST00000389142SORBS2chr4

186578578

-OS9chr12

58109543

+
intron-intronENST00000418609ENST00000413095SORBS2chr4

186578578

-OS9chr12

58109543

+
intron-intronENST00000418609ENST00000435406SORBS2chr4

186578578

-OS9chr12

58109543

+
intron-intronENST00000418609ENST00000551035SORBS2chr4

186578578

-OS9chr12

58109543

+
intron-intronENST00000498125ENST00000257966SORBS2chr4

186578578

-OS9chr12

58109543

+
intron-intronENST00000498125ENST00000389142SORBS2chr4

186578578

-OS9chr12

58109543

+
intron-intronENST00000498125ENST00000413095SORBS2chr4

186578578

-OS9chr12

58109543

+
intron-intronENST00000498125ENST00000435406SORBS2chr4

186578578

-OS9chr12

58109543

+
intron-intronENST00000498125ENST00000551035SORBS2chr4

186578578

-OS9chr12

58109543

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000284776SORBS2chr4186578578-ENST00000552285OS9chr1258109543+21267773032036577
ENST00000284776SORBS2chr4186578578-ENST00000315970OS9chr1258109543+28487773032201632
ENST00000284776SORBS2chr4186578578-ENST00000439210OS9chr1258109543+23027773031991562
ENST00000284776SORBS2chr4186578578-ENST00000389146OS9chr1258109543+22727773032156617
ENST00000393528SORBS2chr4186578578-ENST00000552285OS9chr1258109543+249211436752402575
ENST00000393528SORBS2chr4186578578-ENST00000315970OS9chr1258109543+321411436752567630
ENST00000393528SORBS2chr4186578578-ENST00000439210OS9chr1258109543+266811436752357560
ENST00000393528SORBS2chr4186578578-ENST00000389146OS9chr1258109543+263811436752522615

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000284776ENST00000552285SORBS2chr4186578578-OS9chr1258109543+0.0066735440.9933264
ENST00000284776ENST00000315970SORBS2chr4186578578-OS9chr1258109543+0.0070969190.99290305
ENST00000284776ENST00000439210SORBS2chr4186578578-OS9chr1258109543+0.0066943910.9933056
ENST00000284776ENST00000389146SORBS2chr4186578578-OS9chr1258109543+0.0094118860.99058807
ENST00000393528ENST00000552285SORBS2chr4186578578-OS9chr1258109543+0.0074527450.9925472
ENST00000393528ENST00000315970SORBS2chr4186578578-OS9chr1258109543+0.0074601150.99253994
ENST00000393528ENST00000439210SORBS2chr4186578578-OS9chr1258109543+0.0072266240.99277335
ENST00000393528ENST00000389146SORBS2chr4186578578-OS9chr1258109543+0.0077494290.9922505

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Fusion Genomic Features for SORBS2-OS9


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
SORBS2chr4186578577-OS9chr1258109542+6.24E-091
SORBS2chr4186578577-OS9chr1258109542+6.24E-091

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for SORBS2-OS9


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr4:186578578/chr12:58109543)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneSORBS2chr4:186578578chr12:58109543ENST00000355634-924167_1821891201.0Compositional biasNote=Pro-rich
HgeneSORBS2chr4:186578578chr12:58109543ENST00000437304-723167_182268825.0Compositional biasNote=Pro-rich
HgeneSORBS2chr4:186578578chr12:58109543ENST00000319471-72366_127175732.0DomainSoHo
HgeneSORBS2chr4:186578578chr12:58109543ENST00000355634-92466_1271891201.0DomainSoHo
HgeneSORBS2chr4:186578578chr12:58109543ENST00000393528-72366_127135667.0DomainSoHo
HgeneSORBS2chr4:186578578chr12:58109543ENST00000437304-72366_127268825.0DomainSoHo
HgeneSORBS2chr4:186578578chr12:58109543ENST00000448662-62166_127158662.0DomainSoHo
HgeneSORBS2chr4:186578578chr12:58109543ENST00000449407-82166_127175645.0DomainSoHo
TgeneOS9chr4:186578578chr12:58109543ENST00000257966414414_429193614.0Compositional biasNote=Asp/Glu-rich (acidic)
TgeneOS9chr4:186578578chr12:58109543ENST00000315970415414_429193668.0Compositional biasNote=Asp/Glu-rich (acidic)
TgeneOS9chr4:186578578chr12:58109543ENST00000389142414414_429193598.0Compositional biasNote=Asp/Glu-rich (acidic)
TgeneOS9chr4:186578578chr12:58109543ENST00000389146415414_429193653.0Compositional biasNote=Asp/Glu-rich (acidic)
TgeneOS9chr4:186578578chr12:58109543ENST00000435406313414_429141561.0Compositional biasNote=Asp/Glu-rich (acidic)
TgeneOS9chr4:186578578chr12:58109543ENST00000439210313414_429134539.0Compositional biasNote=Asp/Glu-rich (acidic)
TgeneOS9chr4:186578578chr12:58109543ENST00000551035313414_429160581.0Compositional biasNote=Asp/Glu-rich (acidic)
TgeneOS9chr4:186578578chr12:58109543ENST00000552285414414_429193613.0Compositional biasNote=Asp/Glu-rich (acidic)

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneSORBS2chr4:186578578chr12:58109543ENST00000284776-621167_182891101.0Compositional biasNote=Pro-rich
HgeneSORBS2chr4:186578578chr12:58109543ENST00000284776-621640_652891101.0Compositional biasNote=His-rich
HgeneSORBS2chr4:186578578chr12:58109543ENST00000284776-621931_934891101.0Compositional biasNote=Poly-Pro
HgeneSORBS2chr4:186578578chr12:58109543ENST00000319471-723167_182175732.0Compositional biasNote=Pro-rich
HgeneSORBS2chr4:186578578chr12:58109543ENST00000319471-723640_652175732.0Compositional biasNote=His-rich
HgeneSORBS2chr4:186578578chr12:58109543ENST00000319471-723931_934175732.0Compositional biasNote=Poly-Pro
HgeneSORBS2chr4:186578578chr12:58109543ENST00000355634-924640_6521891201.0Compositional biasNote=His-rich
HgeneSORBS2chr4:186578578chr12:58109543ENST00000355634-924931_9341891201.0Compositional biasNote=Poly-Pro
HgeneSORBS2chr4:186578578chr12:58109543ENST00000393528-723167_182135667.0Compositional biasNote=Pro-rich
HgeneSORBS2chr4:186578578chr12:58109543ENST00000393528-723640_652135667.0Compositional biasNote=His-rich
HgeneSORBS2chr4:186578578chr12:58109543ENST00000393528-723931_934135667.0Compositional biasNote=Poly-Pro
HgeneSORBS2chr4:186578578chr12:58109543ENST00000418609-115167_18201005.0Compositional biasNote=Pro-rich
HgeneSORBS2chr4:186578578chr12:58109543ENST00000418609-115640_65201005.0Compositional biasNote=His-rich
HgeneSORBS2chr4:186578578chr12:58109543ENST00000418609-115931_93401005.0Compositional biasNote=Poly-Pro
HgeneSORBS2chr4:186578578chr12:58109543ENST00000431808-722167_182891101.0Compositional biasNote=Pro-rich
HgeneSORBS2chr4:186578578chr12:58109543ENST00000431808-722640_652891101.0Compositional biasNote=His-rich
HgeneSORBS2chr4:186578578chr12:58109543ENST00000431808-722931_934891101.0Compositional biasNote=Poly-Pro
HgeneSORBS2chr4:186578578chr12:58109543ENST00000437304-723640_652268825.0Compositional biasNote=His-rich
HgeneSORBS2chr4:186578578chr12:58109543ENST00000437304-723931_934268825.0Compositional biasNote=Poly-Pro
HgeneSORBS2chr4:186578578chr12:58109543ENST00000448662-621167_182158662.0Compositional biasNote=Pro-rich
HgeneSORBS2chr4:186578578chr12:58109543ENST00000448662-621640_652158662.0Compositional biasNote=His-rich
HgeneSORBS2chr4:186578578chr12:58109543ENST00000448662-621931_934158662.0Compositional biasNote=Poly-Pro
HgeneSORBS2chr4:186578578chr12:58109543ENST00000449407-821167_182175645.0Compositional biasNote=Pro-rich
HgeneSORBS2chr4:186578578chr12:58109543ENST00000449407-821640_652175645.0Compositional biasNote=His-rich
HgeneSORBS2chr4:186578578chr12:58109543ENST00000449407-821931_934175645.0Compositional biasNote=Poly-Pro
HgeneSORBS2chr4:186578578chr12:58109543ENST00000284776-6211041_1100891101.0DomainSH3 3
HgeneSORBS2chr4:186578578chr12:58109543ENST00000284776-62166_127891101.0DomainSoHo
HgeneSORBS2chr4:186578578chr12:58109543ENST00000284776-621863_922891101.0DomainSH3 1
HgeneSORBS2chr4:186578578chr12:58109543ENST00000284776-621938_999891101.0DomainSH3 2
HgeneSORBS2chr4:186578578chr12:58109543ENST00000319471-7231041_1100175732.0DomainSH3 3
HgeneSORBS2chr4:186578578chr12:58109543ENST00000319471-723863_922175732.0DomainSH3 1
HgeneSORBS2chr4:186578578chr12:58109543ENST00000319471-723938_999175732.0DomainSH3 2
HgeneSORBS2chr4:186578578chr12:58109543ENST00000355634-9241041_11001891201.0DomainSH3 3
HgeneSORBS2chr4:186578578chr12:58109543ENST00000355634-924863_9221891201.0DomainSH3 1
HgeneSORBS2chr4:186578578chr12:58109543ENST00000355634-924938_9991891201.0DomainSH3 2
HgeneSORBS2chr4:186578578chr12:58109543ENST00000393528-7231041_1100135667.0DomainSH3 3
HgeneSORBS2chr4:186578578chr12:58109543ENST00000393528-723863_922135667.0DomainSH3 1
HgeneSORBS2chr4:186578578chr12:58109543ENST00000393528-723938_999135667.0DomainSH3 2
HgeneSORBS2chr4:186578578chr12:58109543ENST00000418609-1151041_110001005.0DomainSH3 3
HgeneSORBS2chr4:186578578chr12:58109543ENST00000418609-11566_12701005.0DomainSoHo
HgeneSORBS2chr4:186578578chr12:58109543ENST00000418609-115863_92201005.0DomainSH3 1
HgeneSORBS2chr4:186578578chr12:58109543ENST00000418609-115938_99901005.0DomainSH3 2
HgeneSORBS2chr4:186578578chr12:58109543ENST00000431808-7221041_1100891101.0DomainSH3 3
HgeneSORBS2chr4:186578578chr12:58109543ENST00000431808-72266_127891101.0DomainSoHo
HgeneSORBS2chr4:186578578chr12:58109543ENST00000431808-722863_922891101.0DomainSH3 1
HgeneSORBS2chr4:186578578chr12:58109543ENST00000431808-722938_999891101.0DomainSH3 2
HgeneSORBS2chr4:186578578chr12:58109543ENST00000437304-7231041_1100268825.0DomainSH3 3
HgeneSORBS2chr4:186578578chr12:58109543ENST00000437304-723863_922268825.0DomainSH3 1
HgeneSORBS2chr4:186578578chr12:58109543ENST00000437304-723938_999268825.0DomainSH3 2
HgeneSORBS2chr4:186578578chr12:58109543ENST00000448662-6211041_1100158662.0DomainSH3 3
HgeneSORBS2chr4:186578578chr12:58109543ENST00000448662-621863_922158662.0DomainSH3 1
HgeneSORBS2chr4:186578578chr12:58109543ENST00000448662-621938_999158662.0DomainSH3 2
HgeneSORBS2chr4:186578578chr12:58109543ENST00000449407-8211041_1100175645.0DomainSH3 3
HgeneSORBS2chr4:186578578chr12:58109543ENST00000449407-821863_922175645.0DomainSH3 1
HgeneSORBS2chr4:186578578chr12:58109543ENST00000449407-821938_999175645.0DomainSH3 2
TgeneOS9chr4:186578578chr12:58109543ENST00000257966414108_230193614.0DomainMRH
TgeneOS9chr4:186578578chr12:58109543ENST00000315970415108_230193668.0DomainMRH
TgeneOS9chr4:186578578chr12:58109543ENST00000389142414108_230193598.0DomainMRH
TgeneOS9chr4:186578578chr12:58109543ENST00000389146415108_230193653.0DomainMRH
TgeneOS9chr4:186578578chr12:58109543ENST00000435406313108_230141561.0DomainMRH
TgeneOS9chr4:186578578chr12:58109543ENST00000439210313108_230134539.0DomainMRH
TgeneOS9chr4:186578578chr12:58109543ENST00000551035313108_230160581.0DomainMRH
TgeneOS9chr4:186578578chr12:58109543ENST00000552285414108_230193613.0DomainMRH


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Fusion Gene Sequence for SORBS2-OS9


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>85192_85192_1_SORBS2-OS9_SORBS2_chr4_186578578_ENST00000284776_OS9_chr12_58109543_ENST00000315970_length(transcript)=2848nt_BP=777nt
TCCTTTTATTGTGGATGAACACCACGTACATGCCGTAAATGCTCCCTAGGCTGGCTGCGGCTACAAGGCAGACCCGGGAGCTGAGAATAG
AGGAATACCTGCCCAAGCAACTCATTCTGCACAGCAGCCGACAAGACAGCGATTTTCCTGTGCTGGAATGTGCCCATCCAAAGACACTTG
GATTGGACTTAATCTTAAACCTCTGGAGTTCAAGACCTTTTAAAAAGGGCTAAATAAACAATCTCTACATGTAAAAGGCCACTGACTCCT
ACTTCCTCTGTATAGAGCAACTGTTGAACTCAGCTGCCTGTAGGGCGTGATTCTCAGTCACCAGACTCAGCTTGGAGATCTTACAATGAT
GGCAATCAGGAGACACTGAACGGAGATGCTACATATTCCTCTCTTGCAGCAAAAGGTTTTAGAAGCGTTCGACCAAACCTACAAGATAAA
AGATCACCAACTCAGAGCCAGATAACAGTGAATGGAAACTCAGGAGGTGCCGTGAGTCCCATGAGTTACTATCAGAGGCCGTTTTCCCCC
TCGGCATATTCTCTCCCAGCCTCACTCAACTCCAGCATTGTCATGCAGCACGGCACATCCCTCGATTCCACAGACACATATCCCCAGCAT
GCGCAGTCTCTGGATGGCACCACCAGCAGCTCTATCCCCCTGTACCGATCCTCAGAGGAAGAGAAGAGAGTGACAGTCATCAAAGCCCCG
CATTACCCAGGGATCGGGCCCGTGGATGAATCCGGAATCCCCACAGCAATTAGAACGTTCCTCTGTGACGAGGGTGCAGGTATCTCTGGG
GACTACATCGATCGCGTGGACGAGCCCTTGTCCTGCTCTTATGTGCTGACCATTCGCACTCCTCGGCTCTGCCCCCACCCTCTCCTCCGG
CCCCCACCCAGTGCTGCACCGCAGGCCATCCTCTGTCACCCTTCCCTACAGCCTGAGGAGTACATGGCCTACGTTCAGAGGCAAGCCGAC
TCAAAGCAGTATGGAGATAAAATCATAGAGGAGCTGCAAGATCTAGGCCCCCAAGTGTGGAGTGAGACCAAGTCTGGGGTGGCACCCCAA
AAGATGGCAGGTGCGAGCCCGACCAAGGATGACAGTAAGGACTCAGATTTCTGGAAGATGCTTAATGAGCCAGAGGACCAGGCCCCAGGA
GGGGAGGAGGTGCCGGCTGAGGAGCAGGACCCAAGCCCTGAGGCAGCAGATTCAGCTTCTGGTGCTCCCAATGATTTTCAGAACAACGTG
CAGGTCAAAGTCATTCGAAGCCCTGCGGATTTGATTCGATTCATAGAGGAGCTGAAAGGTGGAACAAAAAAGGGGAAGCCAAATATAGGC
CAAGAGCAGCCTGTGGATGATGCTGCAGAAGTCCCTCAGAGGGAACCAGAGAAGGAAAGGGGTGATCCAGAACGGCAGAGAGAGATGGAA
GAAGAGGAGGATGAGGATGAGGATGAGGATGAAGATGAGGATGAACGGCAGTTACTGGGAGAATTTGAGAAGGAACTGGAAGGGATCCTG
CTTCCGTCAGACCGAGACCGGCTCCGTTCGGAGGTGAAGGCTGGCATGGAGCGGGAACTGGAAAACATCATCCAGGAGACAGAGAAAGAG
CTGGACCCAGATGGGCTGAAGAAGGAGTCAGAGCGGGATCGGGCAATGCTGGCTCTCACATCCACTCTCAACAAACTCATCAAAAGACTG
GAGGAAAAACAGAGTCCAGAGCTGGTGAAGAAGCACAAGAAAAAGAGGGTTGTCCCCAAAAAGCCTCCCCCATCACCCCAACCTACAGAG
GAGGATCCTGAGCACAGAGTCCGGGTCCGGGTCACCAAGCTCCGTCTCGGAGGCCCTAATCAGGATCTGACTGTCCTCGAGATGAAACGG
GAAAACCCACAGCTGAAACAAATCGAGGGGCTGGTGAAGGAGCTGCTGGAGAGGGAGGGACTCACAGCTGCAGGGAAAATTGAGATCAAA
ATTGTCCGCCCATGGGCTGAAGGGACTGAAGAGGGTGCACGTTGGCTGACTGATGAGGACACGAGAAACCTCAAGGAGATCTTCTTCAAT
ATCTTGGTGCCGGGAGCTGAAGAGGCCCAGAAGGAACGCCAGCGGCAGAAAGAGCTGGAGAGCAATTACCGCCGGGTGTGGGGCTCTCCA
GGTGGGGAGGGCACAGGGGACCTGGACGAATTTGACTTCTGAGACCAACACTACACTTGACCCTTCACGGAATCCAGACTCTTCCTGGAC
TGGCTTGCCTCCTCCCCACCTCCCCACCCTGGAACCCCTGAGGGCCAAACAGCAGAGTGGAGCTGAGCTGTGGACCTCTCGGGCAACTCT
GTGGGTGTGGGGGCCCTGGGTGAATGCTGCTGCCCCTGCTGGCAGCCACCTTGAGACCTCACCGGGCCTGTGATATTTGCTCTCCTGAAC
TCTCACTCAATCCTCTTCCTCTCCTCTGTGGCTTTTCCTGTTATTGTCCCCTAATGATAGGATATTCCCTGCTGCCTACCTGGAGATTCA
GTAGGATCTTTTGAGTGGAGGTGGGTAGAGAGAGCAAGGAGGGCAGGACACTTAGCAGGCACTGAGCAAGCAGGCCCCCACCTGCCCTTA
GTGATGTTTGGAGTCGTTTTACCCTCTTCTATTGAATTGCCTTGGGATTTCCTTCTCCCTTTCCCTGCCCACCCTGTCCCCTACAATTTG
TGCTTCTGAGTTGAGGAGCCTTCACCTCTGTTGCTGAGGAAATGGTAGAATGCTGCCTATCACCTCCAGCACAATCCCAGTGAAAAAGGT

>85192_85192_1_SORBS2-OS9_SORBS2_chr4_186578578_ENST00000284776_OS9_chr12_58109543_ENST00000315970_length(amino acids)=632AA_BP=158
MPVGRDSQSPDSAWRSYNDGNQETLNGDATYSSLAAKGFRSVRPNLQDKRSPTQSQITVNGNSGGAVSPMSYYQRPFSPSAYSLPASLNS
SIVMQHGTSLDSTDTYPQHAQSLDGTTSSSIPLYRSSEEEKRVTVIKAPHYPGIGPVDESGIPTAIRTFLCDEGAGISGDYIDRVDEPLS
CSYVLTIRTPRLCPHPLLRPPPSAAPQAILCHPSLQPEEYMAYVQRQADSKQYGDKIIEELQDLGPQVWSETKSGVAPQKMAGASPTKDD
SKDSDFWKMLNEPEDQAPGGEEVPAEEQDPSPEAADSASGAPNDFQNNVQVKVIRSPADLIRFIEELKGGTKKGKPNIGQEQPVDDAAEV
PQREPEKERGDPERQREMEEEEDEDEDEDEDEDERQLLGEFEKELEGILLPSDRDRLRSEVKAGMERELENIIQETEKELDPDGLKKESE
RDRAMLALTSTLNKLIKRLEEKQSPELVKKHKKKRVVPKKPPPSPQPTEEDPEHRVRVRVTKLRLGGPNQDLTVLEMKRENPQLKQIEGL
VKELLEREGLTAAGKIEIKIVRPWAEGTEEGARWLTDEDTRNLKEIFFNILVPGAEEAQKERQRQKELESNYRRVWGSPGGEGTGDLDEF

--------------------------------------------------------------
>85192_85192_2_SORBS2-OS9_SORBS2_chr4_186578578_ENST00000284776_OS9_chr12_58109543_ENST00000389146_length(transcript)=2272nt_BP=777nt
TCCTTTTATTGTGGATGAACACCACGTACATGCCGTAAATGCTCCCTAGGCTGGCTGCGGCTACAAGGCAGACCCGGGAGCTGAGAATAG
AGGAATACCTGCCCAAGCAACTCATTCTGCACAGCAGCCGACAAGACAGCGATTTTCCTGTGCTGGAATGTGCCCATCCAAAGACACTTG
GATTGGACTTAATCTTAAACCTCTGGAGTTCAAGACCTTTTAAAAAGGGCTAAATAAACAATCTCTACATGTAAAAGGCCACTGACTCCT
ACTTCCTCTGTATAGAGCAACTGTTGAACTCAGCTGCCTGTAGGGCGTGATTCTCAGTCACCAGACTCAGCTTGGAGATCTTACAATGAT
GGCAATCAGGAGACACTGAACGGAGATGCTACATATTCCTCTCTTGCAGCAAAAGGTTTTAGAAGCGTTCGACCAAACCTACAAGATAAA
AGATCACCAACTCAGAGCCAGATAACAGTGAATGGAAACTCAGGAGGTGCCGTGAGTCCCATGAGTTACTATCAGAGGCCGTTTTCCCCC
TCGGCATATTCTCTCCCAGCCTCACTCAACTCCAGCATTGTCATGCAGCACGGCACATCCCTCGATTCCACAGACACATATCCCCAGCAT
GCGCAGTCTCTGGATGGCACCACCAGCAGCTCTATCCCCCTGTACCGATCCTCAGAGGAAGAGAAGAGAGTGACAGTCATCAAAGCCCCG
CATTACCCAGGGATCGGGCCCGTGGATGAATCCGGAATCCCCACAGCAATTAGAACGTTCCTCTGTGACGAGGGTGCAGGTATCTCTGGG
GACTACATCGATCGCGTGGACGAGCCCTTGTCCTGCTCTTATGTGCTGACCATTCGCACTCCTCGGCTCTGCCCCCACCCTCTCCTCCGG
CCCCCACCCAGTGCTGCACCGCAGGCCATCCTCTGTCACCCTTCCCTACAGCCTGAGGAGTACATGGCCTACGTTCAGAGGCAAGCCGAC
TCAAAGCAGTATGGAGATAAAATCATAGAGGAGCTGCAAGATCTAGGCCCCCAAGTGTGGAGTGAGACCAAGTCTGGGGTGGCACCCCAA
AAGATGGCAGGTGCGAGCCCGACCAAGGATGACAGTAAGGACTCAGATTTCTGGAAGATGCTTAATGAGCCAGAGGACCAGGCCCCAGGA
GGGGAGGAGGTGCCGGCTGAGGAGCAGGACCCAAGCCCTGAGGCAGCAGATTCAGCTTCTGGTGCTCCCAATGATTTTCAGAACAACGTG
CAGGTCAAAGTCATTCGAAGCCCTGCGGATTTGATTCGATTCATAGAGGAGCTGAAAGGTGGAACAAAAAAGGGGAAGCCAAATATAGGC
CAAGAGCAGCCTGTGGATGATGCTGCAGAAGTCCCTCAGAGGGAACCAGAGAAGGAAAGGGGTGATCCAGAACGGCAGAGAGAGATGGAA
GAAGAGGAGGATGAGGATGAGGATGAGGATGAAGATGAGGATGAACGGCAGTTACTGGGAGAATTTGAGAAGGAACTGGAAGGGATCCTG
CTTCCGTCAGACCGAGACCGGCTCCGTTCGGAGACAGAGAAAGAGCTGGACCCAGATGGGCTGAAGAAGGAGTCAGAGCGGGATCGGGCA
ATGCTGGCTCTCACATCCACTCTCAACAAACTCATCAAAAGACTGGAGGAAAAACAGAGTCCAGAGCTGGTGAAGAAGCACAAGAAAAAG
AGGGTTGTCCCCAAAAAGCCTCCCCCATCACCCCAACCTACAGAGGAGGATCCTGAGCACAGAGTCCGGGTCCGGGTCACCAAGCTCCGT
CTCGGAGGCCCTAATCAGGATCTGACTGTCCTCGAGATGAAACGGGAAAACCCACAGCTGAAACAAATCGAGGGGCTGGTGAAGGAGCTG
CTGGAGAGGGAGGGACTCACAGCTGCAGGGAAAATTGAGATCAAAATTGTCCGCCCATGGGCTGAAGGGACTGAAGAGGGTGCACGTTGG
CTGACTGATGAGGACACGAGAAACCTCAAGGAGATCTTCTTCAATATCTTGGTGCCGGGAGCTGAAGAGGCCCAGAAGGAACGCCAGCGG
CAGAAAGAGCTGGAGAGCAATTACCGCCGGGTGTGGGGCTCTCCAGGTGGGGAGGGCACAGGGGACCTGGACGAATTTGACTTCTGAGAC
CAACACTACACTTGACCCTTCACGGAATCCAGACTCTTCCTGGACTGGCTTGCCTCCTCCCCACCTCCCCACCCTGGAACCCCTGAGGGC

>85192_85192_2_SORBS2-OS9_SORBS2_chr4_186578578_ENST00000284776_OS9_chr12_58109543_ENST00000389146_length(amino acids)=617AA_BP=158
MPVGRDSQSPDSAWRSYNDGNQETLNGDATYSSLAAKGFRSVRPNLQDKRSPTQSQITVNGNSGGAVSPMSYYQRPFSPSAYSLPASLNS
SIVMQHGTSLDSTDTYPQHAQSLDGTTSSSIPLYRSSEEEKRVTVIKAPHYPGIGPVDESGIPTAIRTFLCDEGAGISGDYIDRVDEPLS
CSYVLTIRTPRLCPHPLLRPPPSAAPQAILCHPSLQPEEYMAYVQRQADSKQYGDKIIEELQDLGPQVWSETKSGVAPQKMAGASPTKDD
SKDSDFWKMLNEPEDQAPGGEEVPAEEQDPSPEAADSASGAPNDFQNNVQVKVIRSPADLIRFIEELKGGTKKGKPNIGQEQPVDDAAEV
PQREPEKERGDPERQREMEEEEDEDEDEDEDEDERQLLGEFEKELEGILLPSDRDRLRSETEKELDPDGLKKESERDRAMLALTSTLNKL
IKRLEEKQSPELVKKHKKKRVVPKKPPPSPQPTEEDPEHRVRVRVTKLRLGGPNQDLTVLEMKRENPQLKQIEGLVKELLEREGLTAAGK

--------------------------------------------------------------
>85192_85192_3_SORBS2-OS9_SORBS2_chr4_186578578_ENST00000284776_OS9_chr12_58109543_ENST00000439210_length(transcript)=2302nt_BP=777nt
TCCTTTTATTGTGGATGAACACCACGTACATGCCGTAAATGCTCCCTAGGCTGGCTGCGGCTACAAGGCAGACCCGGGAGCTGAGAATAG
AGGAATACCTGCCCAAGCAACTCATTCTGCACAGCAGCCGACAAGACAGCGATTTTCCTGTGCTGGAATGTGCCCATCCAAAGACACTTG
GATTGGACTTAATCTTAAACCTCTGGAGTTCAAGACCTTTTAAAAAGGGCTAAATAAACAATCTCTACATGTAAAAGGCCACTGACTCCT
ACTTCCTCTGTATAGAGCAACTGTTGAACTCAGCTGCCTGTAGGGCGTGATTCTCAGTCACCAGACTCAGCTTGGAGATCTTACAATGAT
GGCAATCAGGAGACACTGAACGGAGATGCTACATATTCCTCTCTTGCAGCAAAAGGTTTTAGAAGCGTTCGACCAAACCTACAAGATAAA
AGATCACCAACTCAGAGCCAGATAACAGTGAATGGAAACTCAGGAGGTGCCGTGAGTCCCATGAGTTACTATCAGAGGCCGTTTTCCCCC
TCGGCATATTCTCTCCCAGCCTCACTCAACTCCAGCATTGTCATGCAGCACGGCACATCCCTCGATTCCACAGACACATATCCCCAGCAT
GCGCAGTCTCTGGATGGCACCACCAGCAGCTCTATCCCCCTGTACCGATCCTCAGAGGAAGAGAAGAGAGTGACAGTCATCAAAGCCCCG
CATTACCCAGGGATCGGGCCCGTGGATGAATCCGGAATCCCCACAGCAATTAGAACGTTCCTCTGTGACGAGGGTGCAGGTATCTCTGGG
GACTACATCGATCGCGTGGACGAGCCCTTGTCCTGCTCTTATGTGCTGACCATTCGCACTCCTCGGCTCTGCCCCCACCCTCTCCTCCGG
CCCCCACCCAGTGCTGCACCGCAGGCCATCCTCTGTCACCCTTCCCTACAGCCTGAGGAGTACATGGCCTACGTTCAGAGGCAAGCCGAC
TCAAAGCAGTATGGAGATAAAATCATAGAGGAGCTGCAAGATCTAGGCCCCCAAGTGTGGAGTGAGACCAAGTCTGGGGTGGCACCCCAA
AAGATGGCAGGTGCGAGCCCGACCAAGGATGACAGTAAGGACTCAGATTTCTGGAAGATGCTTAATGAGCCAGAGGACCAGGCCCCAGGA
GGGGAGGAGGTGCCGGCTGAGGAGCAGGACCCAAGCCCTGAGGCAGCAGATTCAGCTTCTGGTGCTCCCAATGATTTTCAGAACAACGTG
CAGGTCAAAGTCATTCGAAGCCCTGCGGATTTGATTCGATTCATAGAGGAGCTGAAAGGTGGAACAAAAAAGGGGAAGCCAAATATAGGC
CAAGAGCAGCCTGTGGATGATGCTGCAGAAGTCCCTCAGAGGGAACCAGAGAAGGAAAGGGGTGATCCAGAACGGCAGAGAGAGATGGAA
GAAGAGGAGGATGAGGATGAGGATGAGGATGAAGATGAGGATGAACGGCAGTTACTGGGAGAATTTGAGAAGGAACTGGAAGGGATCCTG
CTTCCGTCAGACCGAGACCGGCTCCGTTCGGAGACAGAGAAAGAGCTGGACCCAGATGGGCTGAAGAAGGAGTCAGAGCGGGATCGGGCA
ATGCTGGCTCTCACATCCACTCTCAACAAACTCATCAAAAGACTGGAGGAAAAACAGAGTCCAGAGCTGGTGAAGAAGCACAAGAAAAAG
AGGGTTGTCCCCAAAAAGCCTCCCCCATCACCCCAACCTACAGGGAAAATTGAGATCAAAATTGTCCGCCCATGGGCTGAAGGGACTGAA
GAGGGTGCACGTTGGCTGACTGATGAGGACACGAGAAACCTCAAGGAGATCTTCTTCAATATCTTGGTGCCGGGAGCTGAAGAGGCCCAG
AAGGAACGCCAGCGGCAGAAAGAGCTGGAGAGCAATTACCGCCGGGTGTGGGGCTCTCCAGGTGGGGAGGGCACAGGGGACCTGGACGAA
TTTGACTTCTGAGACCAACACTACACTTGACCCTTCACGGAATCCAGACTCTTCCTGGACTGGCTTGCCTCCTCCCCACCTCCCCACCCT
GGAACCCCTGAGGGCCAAACAGCAGAGTGGAGCTGAGCTGTGGACCTCTCGGGCAACTCTGTGGGTGTGGGGGCCCTGGGTGAATGCTGC
TGCCCCTGCTGGCAGCCACCTTGAGACCTCACCGGGCCTGTGATATTTGCTCTCCTGAACTCTCACTCAATCCTCTTCCTCTCCTCTGTG

>85192_85192_3_SORBS2-OS9_SORBS2_chr4_186578578_ENST00000284776_OS9_chr12_58109543_ENST00000439210_length(amino acids)=562AA_BP=158
MPVGRDSQSPDSAWRSYNDGNQETLNGDATYSSLAAKGFRSVRPNLQDKRSPTQSQITVNGNSGGAVSPMSYYQRPFSPSAYSLPASLNS
SIVMQHGTSLDSTDTYPQHAQSLDGTTSSSIPLYRSSEEEKRVTVIKAPHYPGIGPVDESGIPTAIRTFLCDEGAGISGDYIDRVDEPLS
CSYVLTIRTPRLCPHPLLRPPPSAAPQAILCHPSLQPEEYMAYVQRQADSKQYGDKIIEELQDLGPQVWSETKSGVAPQKMAGASPTKDD
SKDSDFWKMLNEPEDQAPGGEEVPAEEQDPSPEAADSASGAPNDFQNNVQVKVIRSPADLIRFIEELKGGTKKGKPNIGQEQPVDDAAEV
PQREPEKERGDPERQREMEEEEDEDEDEDEDEDERQLLGEFEKELEGILLPSDRDRLRSETEKELDPDGLKKESERDRAMLALTSTLNKL
IKRLEEKQSPELVKKHKKKRVVPKKPPPSPQPTGKIEIKIVRPWAEGTEEGARWLTDEDTRNLKEIFFNILVPGAEEAQKERQRQKELES

--------------------------------------------------------------
>85192_85192_4_SORBS2-OS9_SORBS2_chr4_186578578_ENST00000284776_OS9_chr12_58109543_ENST00000552285_length(transcript)=2126nt_BP=777nt
TCCTTTTATTGTGGATGAACACCACGTACATGCCGTAAATGCTCCCTAGGCTGGCTGCGGCTACAAGGCAGACCCGGGAGCTGAGAATAG
AGGAATACCTGCCCAAGCAACTCATTCTGCACAGCAGCCGACAAGACAGCGATTTTCCTGTGCTGGAATGTGCCCATCCAAAGACACTTG
GATTGGACTTAATCTTAAACCTCTGGAGTTCAAGACCTTTTAAAAAGGGCTAAATAAACAATCTCTACATGTAAAAGGCCACTGACTCCT
ACTTCCTCTGTATAGAGCAACTGTTGAACTCAGCTGCCTGTAGGGCGTGATTCTCAGTCACCAGACTCAGCTTGGAGATCTTACAATGAT
GGCAATCAGGAGACACTGAACGGAGATGCTACATATTCCTCTCTTGCAGCAAAAGGTTTTAGAAGCGTTCGACCAAACCTACAAGATAAA
AGATCACCAACTCAGAGCCAGATAACAGTGAATGGAAACTCAGGAGGTGCCGTGAGTCCCATGAGTTACTATCAGAGGCCGTTTTCCCCC
TCGGCATATTCTCTCCCAGCCTCACTCAACTCCAGCATTGTCATGCAGCACGGCACATCCCTCGATTCCACAGACACATATCCCCAGCAT
GCGCAGTCTCTGGATGGCACCACCAGCAGCTCTATCCCCCTGTACCGATCCTCAGAGGAAGAGAAGAGAGTGACAGTCATCAAAGCCCCG
CATTACCCAGGGATCGGGCCCGTGGATGAATCCGGAATCCCCACAGCAATTAGAACGTTCCTCTGTGACGAGGGTGCAGGTATCTCTGGG
GACTACATCGATCGCGTGGACGAGCCCTTGTCCTGCTCTTATGTGCTGACCATTCGCACTCCTCGGCTCTGCCCCCACCCTCTCCTCCGG
CCCCCACCCAGTGCTGCACCGCAGGCCATCCTCTGTCACCCTTCCCTACAGCCTGAGGAGTACATGGCCTACGTTCAGAGGCAAGCCGAC
TCAAAGCAGTATGGAGATAAAATCATAGAGGAGCTGCAAGATCTAGGCCCCCAAGTGTGGAGTGAGACCAAGTCTGGGGTGGCACCCCAA
AAGATGGCAGGTGCGAGCCCGACCAAGGATGACAGTAAGGACTCAGATTTCTGGAAGATGCTTAATGAGCCAGAGGACCAGGCCCCAGGA
GGGGAGGAGGTGCCGGCTGAGGAGCAGGACCCAAGCCCTGAGGCAGCAGATTCAGCTTCTGGTGCTCCCAATGATTTTCAGAACAACGTG
CAGGTCAAAGTCATTCGAAGCCCTGCGGATTTGATTCGATTCATAGAGGAGCTGAAAGGTGGAACAAAAAAGGGGAAGCCAAATATAGGC
CAAGAGCAGCCTGTGGATGATGCTGCAGAAGTCCCTCAGAGGGAACCAGAGAAGGAAAGGGGTGATCCAGAACGGCAGAGAGAGATGGAA
GAAGAGGAGGATGAGGATGAGGATGAGGATGAAGATGAGGATGAACGGCAGTTACTGGGAGAATTTGAGAAGGAACTGGAAGGGATCCTG
CTTCCGTCAGACCGAGACCGGCTCCGTTCGGAGGTGAAGGCTGGCATGGAGCGGGAACTGGAAAACATCATCCAGGAGACAGAGAAAGAG
CTGGACCCAGATGGGCTGAAGAAGGAGTCAGAGCGGGATCGGGCAATGCTGGCTCTCACATCCACTCTCAACAAACTCATCAAAAGACTG
GAGGAAAAACAGAGTCCAGAGCTGGTGAAGAAGCACAAGAAAAAGAGGGTTGTCCCCAAAAAGCCTCCCCCATCACCCCAACCTACAGGG
AAAATTGAGATCAAAATTGTCCGCCCATGGGCTGAAGGGACTGAAGAGGGTGCACGTTGGCTGACTGATGAGGACACGAGAAACCTCAAG
GAGATCTTCTTCAATATCTTGGTGCCGGGAGCTGAAGAGGCCCAGAAGGAACGCCAGCGGCAGAAAGAGCTGGAGAGCAATTACCGCCGG
GTGTGGGGCTCTCCAGGTGGGGAGGGCACAGGGGACCTGGACGAATTTGACTTCTGAGACCAACACTACACTTGACCCTTCACGGAATCC

>85192_85192_4_SORBS2-OS9_SORBS2_chr4_186578578_ENST00000284776_OS9_chr12_58109543_ENST00000552285_length(amino acids)=577AA_BP=158
MPVGRDSQSPDSAWRSYNDGNQETLNGDATYSSLAAKGFRSVRPNLQDKRSPTQSQITVNGNSGGAVSPMSYYQRPFSPSAYSLPASLNS
SIVMQHGTSLDSTDTYPQHAQSLDGTTSSSIPLYRSSEEEKRVTVIKAPHYPGIGPVDESGIPTAIRTFLCDEGAGISGDYIDRVDEPLS
CSYVLTIRTPRLCPHPLLRPPPSAAPQAILCHPSLQPEEYMAYVQRQADSKQYGDKIIEELQDLGPQVWSETKSGVAPQKMAGASPTKDD
SKDSDFWKMLNEPEDQAPGGEEVPAEEQDPSPEAADSASGAPNDFQNNVQVKVIRSPADLIRFIEELKGGTKKGKPNIGQEQPVDDAAEV
PQREPEKERGDPERQREMEEEEDEDEDEDEDEDERQLLGEFEKELEGILLPSDRDRLRSEVKAGMERELENIIQETEKELDPDGLKKESE
RDRAMLALTSTLNKLIKRLEEKQSPELVKKHKKKRVVPKKPPPSPQPTGKIEIKIVRPWAEGTEEGARWLTDEDTRNLKEIFFNILVPGA

--------------------------------------------------------------
>85192_85192_5_SORBS2-OS9_SORBS2_chr4_186578578_ENST00000393528_OS9_chr12_58109543_ENST00000315970_length(transcript)=3214nt_BP=1143nt
CATTTTACTTATGGAAAACAGTGTGGCATATTCTGCTGAGCTTCGCCCTGGAAGAAGCCTCTTTTATACATCTCTTCAGGGAAGAGAGAA
GCAATGGGCATGTTAGTATACAATGATCACAGCCACGCAGGCCTGCAAGCTGCCTTTTGGACAGGCTGTTGACTGCCGTTCCAATTAGCT
GATTGGAGAATGTGGAATGCAGAGTGATAATGCTGCATATCTGCTATCAGGCAGCAGCAAAGGTTTTTGTCTTGGGAAGGCAAGCTTTCC
CTGCAATATTATCTCAGCAGCTCCCTAGCTGCTTACCCTGAAAACGAGGGATCCAAACGGAGGGTGTTGCACTCTGCTAACGCTGGTCCT
GTGCGTGGCTGTGGCATATGAGCGGCAGGTCTGAAAAAGCAGGTGTGTGCTGGGACGGGCACTGGACTGGAACGCAGGCGGACGCTCTCG
GGTTTACCTGCTTCCTGTTAACAGATTGTGGGCTCCCAGGGCATATGTCTGCACGCTGAGGCCGAGGCGGAGAAGGGGCTTCCTGAGCGT
CCCAGTACACTGACAGAGACACTTGGATTGGACTTAATCTTAAACCTCTGGAGTTCAAGACCTTTTAAAAAGGGCTAAATAAACAATCTC
TACATGTAAAAGGCCACTGACTCCTACTTCCTCTGTATAGAGCAACTGTTGAACTCAGCTGCCTGTAGGAAAACTGAAGACTTTAATAAC
AAACTCTCCAAGGTGAAAATGAACACAGGGCGTGATTCTCAGTCACCAGACTCAGCAAAAGGTTTTAGAAGCGTTCGACCAAACCTACAA
GATAAAAGATCACCAACTCAGAGCCAGATAACAGTGAATGGAAACTCAGGAGGTGCCGTGAGTCCCATGAGTTACTATCAGAGGCCGTTT
TCCCCCTCGGCATATTCTCTCCCAGCCTCACTCAACTCCAGCATTGTCATGCAGCACGGCACATCCCTCGATTCCACAGACACATATCCC
CAGCATGCGCAGTCTCTGGATGGCACCACCAGCAGCTCTATCCCCCTGTACCGATCCTCAGAGGAAGAGAAGAGAGTGACAGTCATCAAA
GCCCCGCATTACCCAGGGATCGGGCCCGTGGATGAATCCGGAATCCCCACAGCAATTAGAACGTTCCTCTGTGACGAGGGTGCAGGTATC
TCTGGGGACTACATCGATCGCGTGGACGAGCCCTTGTCCTGCTCTTATGTGCTGACCATTCGCACTCCTCGGCTCTGCCCCCACCCTCTC
CTCCGGCCCCCACCCAGTGCTGCACCGCAGGCCATCCTCTGTCACCCTTCCCTACAGCCTGAGGAGTACATGGCCTACGTTCAGAGGCAA
GCCGACTCAAAGCAGTATGGAGATAAAATCATAGAGGAGCTGCAAGATCTAGGCCCCCAAGTGTGGAGTGAGACCAAGTCTGGGGTGGCA
CCCCAAAAGATGGCAGGTGCGAGCCCGACCAAGGATGACAGTAAGGACTCAGATTTCTGGAAGATGCTTAATGAGCCAGAGGACCAGGCC
CCAGGAGGGGAGGAGGTGCCGGCTGAGGAGCAGGACCCAAGCCCTGAGGCAGCAGATTCAGCTTCTGGTGCTCCCAATGATTTTCAGAAC
AACGTGCAGGTCAAAGTCATTCGAAGCCCTGCGGATTTGATTCGATTCATAGAGGAGCTGAAAGGTGGAACAAAAAAGGGGAAGCCAAAT
ATAGGCCAAGAGCAGCCTGTGGATGATGCTGCAGAAGTCCCTCAGAGGGAACCAGAGAAGGAAAGGGGTGATCCAGAACGGCAGAGAGAG
ATGGAAGAAGAGGAGGATGAGGATGAGGATGAGGATGAAGATGAGGATGAACGGCAGTTACTGGGAGAATTTGAGAAGGAACTGGAAGGG
ATCCTGCTTCCGTCAGACCGAGACCGGCTCCGTTCGGAGGTGAAGGCTGGCATGGAGCGGGAACTGGAAAACATCATCCAGGAGACAGAG
AAAGAGCTGGACCCAGATGGGCTGAAGAAGGAGTCAGAGCGGGATCGGGCAATGCTGGCTCTCACATCCACTCTCAACAAACTCATCAAA
AGACTGGAGGAAAAACAGAGTCCAGAGCTGGTGAAGAAGCACAAGAAAAAGAGGGTTGTCCCCAAAAAGCCTCCCCCATCACCCCAACCT
ACAGAGGAGGATCCTGAGCACAGAGTCCGGGTCCGGGTCACCAAGCTCCGTCTCGGAGGCCCTAATCAGGATCTGACTGTCCTCGAGATG
AAACGGGAAAACCCACAGCTGAAACAAATCGAGGGGCTGGTGAAGGAGCTGCTGGAGAGGGAGGGACTCACAGCTGCAGGGAAAATTGAG
ATCAAAATTGTCCGCCCATGGGCTGAAGGGACTGAAGAGGGTGCACGTTGGCTGACTGATGAGGACACGAGAAACCTCAAGGAGATCTTC
TTCAATATCTTGGTGCCGGGAGCTGAAGAGGCCCAGAAGGAACGCCAGCGGCAGAAAGAGCTGGAGAGCAATTACCGCCGGGTGTGGGGC
TCTCCAGGTGGGGAGGGCACAGGGGACCTGGACGAATTTGACTTCTGAGACCAACACTACACTTGACCCTTCACGGAATCCAGACTCTTC
CTGGACTGGCTTGCCTCCTCCCCACCTCCCCACCCTGGAACCCCTGAGGGCCAAACAGCAGAGTGGAGCTGAGCTGTGGACCTCTCGGGC
AACTCTGTGGGTGTGGGGGCCCTGGGTGAATGCTGCTGCCCCTGCTGGCAGCCACCTTGAGACCTCACCGGGCCTGTGATATTTGCTCTC
CTGAACTCTCACTCAATCCTCTTCCTCTCCTCTGTGGCTTTTCCTGTTATTGTCCCCTAATGATAGGATATTCCCTGCTGCCTACCTGGA
GATTCAGTAGGATCTTTTGAGTGGAGGTGGGTAGAGAGAGCAAGGAGGGCAGGACACTTAGCAGGCACTGAGCAAGCAGGCCCCCACCTG
CCCTTAGTGATGTTTGGAGTCGTTTTACCCTCTTCTATTGAATTGCCTTGGGATTTCCTTCTCCCTTTCCCTGCCCACCCTGTCCCCTAC
AATTTGTGCTTCTGAGTTGAGGAGCCTTCACCTCTGTTGCTGAGGAAATGGTAGAATGCTGCCTATCACCTCCAGCACAATCCCAGTGAA

>85192_85192_5_SORBS2-OS9_SORBS2_chr4_186578578_ENST00000393528_OS9_chr12_58109543_ENST00000315970_length(amino acids)=630AA_BP=156
MLNSAACRKTEDFNNKLSKVKMNTGRDSQSPDSAKGFRSVRPNLQDKRSPTQSQITVNGNSGGAVSPMSYYQRPFSPSAYSLPASLNSSI
VMQHGTSLDSTDTYPQHAQSLDGTTSSSIPLYRSSEEEKRVTVIKAPHYPGIGPVDESGIPTAIRTFLCDEGAGISGDYIDRVDEPLSCS
YVLTIRTPRLCPHPLLRPPPSAAPQAILCHPSLQPEEYMAYVQRQADSKQYGDKIIEELQDLGPQVWSETKSGVAPQKMAGASPTKDDSK
DSDFWKMLNEPEDQAPGGEEVPAEEQDPSPEAADSASGAPNDFQNNVQVKVIRSPADLIRFIEELKGGTKKGKPNIGQEQPVDDAAEVPQ
REPEKERGDPERQREMEEEEDEDEDEDEDEDERQLLGEFEKELEGILLPSDRDRLRSEVKAGMERELENIIQETEKELDPDGLKKESERD
RAMLALTSTLNKLIKRLEEKQSPELVKKHKKKRVVPKKPPPSPQPTEEDPEHRVRVRVTKLRLGGPNQDLTVLEMKRENPQLKQIEGLVK
ELLEREGLTAAGKIEIKIVRPWAEGTEEGARWLTDEDTRNLKEIFFNILVPGAEEAQKERQRQKELESNYRRVWGSPGGEGTGDLDEFDF

--------------------------------------------------------------
>85192_85192_6_SORBS2-OS9_SORBS2_chr4_186578578_ENST00000393528_OS9_chr12_58109543_ENST00000389146_length(transcript)=2638nt_BP=1143nt
CATTTTACTTATGGAAAACAGTGTGGCATATTCTGCTGAGCTTCGCCCTGGAAGAAGCCTCTTTTATACATCTCTTCAGGGAAGAGAGAA
GCAATGGGCATGTTAGTATACAATGATCACAGCCACGCAGGCCTGCAAGCTGCCTTTTGGACAGGCTGTTGACTGCCGTTCCAATTAGCT
GATTGGAGAATGTGGAATGCAGAGTGATAATGCTGCATATCTGCTATCAGGCAGCAGCAAAGGTTTTTGTCTTGGGAAGGCAAGCTTTCC
CTGCAATATTATCTCAGCAGCTCCCTAGCTGCTTACCCTGAAAACGAGGGATCCAAACGGAGGGTGTTGCACTCTGCTAACGCTGGTCCT
GTGCGTGGCTGTGGCATATGAGCGGCAGGTCTGAAAAAGCAGGTGTGTGCTGGGACGGGCACTGGACTGGAACGCAGGCGGACGCTCTCG
GGTTTACCTGCTTCCTGTTAACAGATTGTGGGCTCCCAGGGCATATGTCTGCACGCTGAGGCCGAGGCGGAGAAGGGGCTTCCTGAGCGT
CCCAGTACACTGACAGAGACACTTGGATTGGACTTAATCTTAAACCTCTGGAGTTCAAGACCTTTTAAAAAGGGCTAAATAAACAATCTC
TACATGTAAAAGGCCACTGACTCCTACTTCCTCTGTATAGAGCAACTGTTGAACTCAGCTGCCTGTAGGAAAACTGAAGACTTTAATAAC
AAACTCTCCAAGGTGAAAATGAACACAGGGCGTGATTCTCAGTCACCAGACTCAGCAAAAGGTTTTAGAAGCGTTCGACCAAACCTACAA
GATAAAAGATCACCAACTCAGAGCCAGATAACAGTGAATGGAAACTCAGGAGGTGCCGTGAGTCCCATGAGTTACTATCAGAGGCCGTTT
TCCCCCTCGGCATATTCTCTCCCAGCCTCACTCAACTCCAGCATTGTCATGCAGCACGGCACATCCCTCGATTCCACAGACACATATCCC
CAGCATGCGCAGTCTCTGGATGGCACCACCAGCAGCTCTATCCCCCTGTACCGATCCTCAGAGGAAGAGAAGAGAGTGACAGTCATCAAA
GCCCCGCATTACCCAGGGATCGGGCCCGTGGATGAATCCGGAATCCCCACAGCAATTAGAACGTTCCTCTGTGACGAGGGTGCAGGTATC
TCTGGGGACTACATCGATCGCGTGGACGAGCCCTTGTCCTGCTCTTATGTGCTGACCATTCGCACTCCTCGGCTCTGCCCCCACCCTCTC
CTCCGGCCCCCACCCAGTGCTGCACCGCAGGCCATCCTCTGTCACCCTTCCCTACAGCCTGAGGAGTACATGGCCTACGTTCAGAGGCAA
GCCGACTCAAAGCAGTATGGAGATAAAATCATAGAGGAGCTGCAAGATCTAGGCCCCCAAGTGTGGAGTGAGACCAAGTCTGGGGTGGCA
CCCCAAAAGATGGCAGGTGCGAGCCCGACCAAGGATGACAGTAAGGACTCAGATTTCTGGAAGATGCTTAATGAGCCAGAGGACCAGGCC
CCAGGAGGGGAGGAGGTGCCGGCTGAGGAGCAGGACCCAAGCCCTGAGGCAGCAGATTCAGCTTCTGGTGCTCCCAATGATTTTCAGAAC
AACGTGCAGGTCAAAGTCATTCGAAGCCCTGCGGATTTGATTCGATTCATAGAGGAGCTGAAAGGTGGAACAAAAAAGGGGAAGCCAAAT
ATAGGCCAAGAGCAGCCTGTGGATGATGCTGCAGAAGTCCCTCAGAGGGAACCAGAGAAGGAAAGGGGTGATCCAGAACGGCAGAGAGAG
ATGGAAGAAGAGGAGGATGAGGATGAGGATGAGGATGAAGATGAGGATGAACGGCAGTTACTGGGAGAATTTGAGAAGGAACTGGAAGGG
ATCCTGCTTCCGTCAGACCGAGACCGGCTCCGTTCGGAGACAGAGAAAGAGCTGGACCCAGATGGGCTGAAGAAGGAGTCAGAGCGGGAT
CGGGCAATGCTGGCTCTCACATCCACTCTCAACAAACTCATCAAAAGACTGGAGGAAAAACAGAGTCCAGAGCTGGTGAAGAAGCACAAG
AAAAAGAGGGTTGTCCCCAAAAAGCCTCCCCCATCACCCCAACCTACAGAGGAGGATCCTGAGCACAGAGTCCGGGTCCGGGTCACCAAG
CTCCGTCTCGGAGGCCCTAATCAGGATCTGACTGTCCTCGAGATGAAACGGGAAAACCCACAGCTGAAACAAATCGAGGGGCTGGTGAAG
GAGCTGCTGGAGAGGGAGGGACTCACAGCTGCAGGGAAAATTGAGATCAAAATTGTCCGCCCATGGGCTGAAGGGACTGAAGAGGGTGCA
CGTTGGCTGACTGATGAGGACACGAGAAACCTCAAGGAGATCTTCTTCAATATCTTGGTGCCGGGAGCTGAAGAGGCCCAGAAGGAACGC
CAGCGGCAGAAAGAGCTGGAGAGCAATTACCGCCGGGTGTGGGGCTCTCCAGGTGGGGAGGGCACAGGGGACCTGGACGAATTTGACTTC
TGAGACCAACACTACACTTGACCCTTCACGGAATCCAGACTCTTCCTGGACTGGCTTGCCTCCTCCCCACCTCCCCACCCTGGAACCCCT

>85192_85192_6_SORBS2-OS9_SORBS2_chr4_186578578_ENST00000393528_OS9_chr12_58109543_ENST00000389146_length(amino acids)=615AA_BP=156
MLNSAACRKTEDFNNKLSKVKMNTGRDSQSPDSAKGFRSVRPNLQDKRSPTQSQITVNGNSGGAVSPMSYYQRPFSPSAYSLPASLNSSI
VMQHGTSLDSTDTYPQHAQSLDGTTSSSIPLYRSSEEEKRVTVIKAPHYPGIGPVDESGIPTAIRTFLCDEGAGISGDYIDRVDEPLSCS
YVLTIRTPRLCPHPLLRPPPSAAPQAILCHPSLQPEEYMAYVQRQADSKQYGDKIIEELQDLGPQVWSETKSGVAPQKMAGASPTKDDSK
DSDFWKMLNEPEDQAPGGEEVPAEEQDPSPEAADSASGAPNDFQNNVQVKVIRSPADLIRFIEELKGGTKKGKPNIGQEQPVDDAAEVPQ
REPEKERGDPERQREMEEEEDEDEDEDEDEDERQLLGEFEKELEGILLPSDRDRLRSETEKELDPDGLKKESERDRAMLALTSTLNKLIK
RLEEKQSPELVKKHKKKRVVPKKPPPSPQPTEEDPEHRVRVRVTKLRLGGPNQDLTVLEMKRENPQLKQIEGLVKELLEREGLTAAGKIE

--------------------------------------------------------------
>85192_85192_7_SORBS2-OS9_SORBS2_chr4_186578578_ENST00000393528_OS9_chr12_58109543_ENST00000439210_length(transcript)=2668nt_BP=1143nt
CATTTTACTTATGGAAAACAGTGTGGCATATTCTGCTGAGCTTCGCCCTGGAAGAAGCCTCTTTTATACATCTCTTCAGGGAAGAGAGAA
GCAATGGGCATGTTAGTATACAATGATCACAGCCACGCAGGCCTGCAAGCTGCCTTTTGGACAGGCTGTTGACTGCCGTTCCAATTAGCT
GATTGGAGAATGTGGAATGCAGAGTGATAATGCTGCATATCTGCTATCAGGCAGCAGCAAAGGTTTTTGTCTTGGGAAGGCAAGCTTTCC
CTGCAATATTATCTCAGCAGCTCCCTAGCTGCTTACCCTGAAAACGAGGGATCCAAACGGAGGGTGTTGCACTCTGCTAACGCTGGTCCT
GTGCGTGGCTGTGGCATATGAGCGGCAGGTCTGAAAAAGCAGGTGTGTGCTGGGACGGGCACTGGACTGGAACGCAGGCGGACGCTCTCG
GGTTTACCTGCTTCCTGTTAACAGATTGTGGGCTCCCAGGGCATATGTCTGCACGCTGAGGCCGAGGCGGAGAAGGGGCTTCCTGAGCGT
CCCAGTACACTGACAGAGACACTTGGATTGGACTTAATCTTAAACCTCTGGAGTTCAAGACCTTTTAAAAAGGGCTAAATAAACAATCTC
TACATGTAAAAGGCCACTGACTCCTACTTCCTCTGTATAGAGCAACTGTTGAACTCAGCTGCCTGTAGGAAAACTGAAGACTTTAATAAC
AAACTCTCCAAGGTGAAAATGAACACAGGGCGTGATTCTCAGTCACCAGACTCAGCAAAAGGTTTTAGAAGCGTTCGACCAAACCTACAA
GATAAAAGATCACCAACTCAGAGCCAGATAACAGTGAATGGAAACTCAGGAGGTGCCGTGAGTCCCATGAGTTACTATCAGAGGCCGTTT
TCCCCCTCGGCATATTCTCTCCCAGCCTCACTCAACTCCAGCATTGTCATGCAGCACGGCACATCCCTCGATTCCACAGACACATATCCC
CAGCATGCGCAGTCTCTGGATGGCACCACCAGCAGCTCTATCCCCCTGTACCGATCCTCAGAGGAAGAGAAGAGAGTGACAGTCATCAAA
GCCCCGCATTACCCAGGGATCGGGCCCGTGGATGAATCCGGAATCCCCACAGCAATTAGAACGTTCCTCTGTGACGAGGGTGCAGGTATC
TCTGGGGACTACATCGATCGCGTGGACGAGCCCTTGTCCTGCTCTTATGTGCTGACCATTCGCACTCCTCGGCTCTGCCCCCACCCTCTC
CTCCGGCCCCCACCCAGTGCTGCACCGCAGGCCATCCTCTGTCACCCTTCCCTACAGCCTGAGGAGTACATGGCCTACGTTCAGAGGCAA
GCCGACTCAAAGCAGTATGGAGATAAAATCATAGAGGAGCTGCAAGATCTAGGCCCCCAAGTGTGGAGTGAGACCAAGTCTGGGGTGGCA
CCCCAAAAGATGGCAGGTGCGAGCCCGACCAAGGATGACAGTAAGGACTCAGATTTCTGGAAGATGCTTAATGAGCCAGAGGACCAGGCC
CCAGGAGGGGAGGAGGTGCCGGCTGAGGAGCAGGACCCAAGCCCTGAGGCAGCAGATTCAGCTTCTGGTGCTCCCAATGATTTTCAGAAC
AACGTGCAGGTCAAAGTCATTCGAAGCCCTGCGGATTTGATTCGATTCATAGAGGAGCTGAAAGGTGGAACAAAAAAGGGGAAGCCAAAT
ATAGGCCAAGAGCAGCCTGTGGATGATGCTGCAGAAGTCCCTCAGAGGGAACCAGAGAAGGAAAGGGGTGATCCAGAACGGCAGAGAGAG
ATGGAAGAAGAGGAGGATGAGGATGAGGATGAGGATGAAGATGAGGATGAACGGCAGTTACTGGGAGAATTTGAGAAGGAACTGGAAGGG
ATCCTGCTTCCGTCAGACCGAGACCGGCTCCGTTCGGAGACAGAGAAAGAGCTGGACCCAGATGGGCTGAAGAAGGAGTCAGAGCGGGAT
CGGGCAATGCTGGCTCTCACATCCACTCTCAACAAACTCATCAAAAGACTGGAGGAAAAACAGAGTCCAGAGCTGGTGAAGAAGCACAAG
AAAAAGAGGGTTGTCCCCAAAAAGCCTCCCCCATCACCCCAACCTACAGGGAAAATTGAGATCAAAATTGTCCGCCCATGGGCTGAAGGG
ACTGAAGAGGGTGCACGTTGGCTGACTGATGAGGACACGAGAAACCTCAAGGAGATCTTCTTCAATATCTTGGTGCCGGGAGCTGAAGAG
GCCCAGAAGGAACGCCAGCGGCAGAAAGAGCTGGAGAGCAATTACCGCCGGGTGTGGGGCTCTCCAGGTGGGGAGGGCACAGGGGACCTG
GACGAATTTGACTTCTGAGACCAACACTACACTTGACCCTTCACGGAATCCAGACTCTTCCTGGACTGGCTTGCCTCCTCCCCACCTCCC
CACCCTGGAACCCCTGAGGGCCAAACAGCAGAGTGGAGCTGAGCTGTGGACCTCTCGGGCAACTCTGTGGGTGTGGGGGCCCTGGGTGAA
TGCTGCTGCCCCTGCTGGCAGCCACCTTGAGACCTCACCGGGCCTGTGATATTTGCTCTCCTGAACTCTCACTCAATCCTCTTCCTCTCC

>85192_85192_7_SORBS2-OS9_SORBS2_chr4_186578578_ENST00000393528_OS9_chr12_58109543_ENST00000439210_length(amino acids)=560AA_BP=156
MLNSAACRKTEDFNNKLSKVKMNTGRDSQSPDSAKGFRSVRPNLQDKRSPTQSQITVNGNSGGAVSPMSYYQRPFSPSAYSLPASLNSSI
VMQHGTSLDSTDTYPQHAQSLDGTTSSSIPLYRSSEEEKRVTVIKAPHYPGIGPVDESGIPTAIRTFLCDEGAGISGDYIDRVDEPLSCS
YVLTIRTPRLCPHPLLRPPPSAAPQAILCHPSLQPEEYMAYVQRQADSKQYGDKIIEELQDLGPQVWSETKSGVAPQKMAGASPTKDDSK
DSDFWKMLNEPEDQAPGGEEVPAEEQDPSPEAADSASGAPNDFQNNVQVKVIRSPADLIRFIEELKGGTKKGKPNIGQEQPVDDAAEVPQ
REPEKERGDPERQREMEEEEDEDEDEDEDEDERQLLGEFEKELEGILLPSDRDRLRSETEKELDPDGLKKESERDRAMLALTSTLNKLIK
RLEEKQSPELVKKHKKKRVVPKKPPPSPQPTGKIEIKIVRPWAEGTEEGARWLTDEDTRNLKEIFFNILVPGAEEAQKERQRQKELESNY

--------------------------------------------------------------
>85192_85192_8_SORBS2-OS9_SORBS2_chr4_186578578_ENST00000393528_OS9_chr12_58109543_ENST00000552285_length(transcript)=2492nt_BP=1143nt
CATTTTACTTATGGAAAACAGTGTGGCATATTCTGCTGAGCTTCGCCCTGGAAGAAGCCTCTTTTATACATCTCTTCAGGGAAGAGAGAA
GCAATGGGCATGTTAGTATACAATGATCACAGCCACGCAGGCCTGCAAGCTGCCTTTTGGACAGGCTGTTGACTGCCGTTCCAATTAGCT
GATTGGAGAATGTGGAATGCAGAGTGATAATGCTGCATATCTGCTATCAGGCAGCAGCAAAGGTTTTTGTCTTGGGAAGGCAAGCTTTCC
CTGCAATATTATCTCAGCAGCTCCCTAGCTGCTTACCCTGAAAACGAGGGATCCAAACGGAGGGTGTTGCACTCTGCTAACGCTGGTCCT
GTGCGTGGCTGTGGCATATGAGCGGCAGGTCTGAAAAAGCAGGTGTGTGCTGGGACGGGCACTGGACTGGAACGCAGGCGGACGCTCTCG
GGTTTACCTGCTTCCTGTTAACAGATTGTGGGCTCCCAGGGCATATGTCTGCACGCTGAGGCCGAGGCGGAGAAGGGGCTTCCTGAGCGT
CCCAGTACACTGACAGAGACACTTGGATTGGACTTAATCTTAAACCTCTGGAGTTCAAGACCTTTTAAAAAGGGCTAAATAAACAATCTC
TACATGTAAAAGGCCACTGACTCCTACTTCCTCTGTATAGAGCAACTGTTGAACTCAGCTGCCTGTAGGAAAACTGAAGACTTTAATAAC
AAACTCTCCAAGGTGAAAATGAACACAGGGCGTGATTCTCAGTCACCAGACTCAGCAAAAGGTTTTAGAAGCGTTCGACCAAACCTACAA
GATAAAAGATCACCAACTCAGAGCCAGATAACAGTGAATGGAAACTCAGGAGGTGCCGTGAGTCCCATGAGTTACTATCAGAGGCCGTTT
TCCCCCTCGGCATATTCTCTCCCAGCCTCACTCAACTCCAGCATTGTCATGCAGCACGGCACATCCCTCGATTCCACAGACACATATCCC
CAGCATGCGCAGTCTCTGGATGGCACCACCAGCAGCTCTATCCCCCTGTACCGATCCTCAGAGGAAGAGAAGAGAGTGACAGTCATCAAA
GCCCCGCATTACCCAGGGATCGGGCCCGTGGATGAATCCGGAATCCCCACAGCAATTAGAACGTTCCTCTGTGACGAGGGTGCAGGTATC
TCTGGGGACTACATCGATCGCGTGGACGAGCCCTTGTCCTGCTCTTATGTGCTGACCATTCGCACTCCTCGGCTCTGCCCCCACCCTCTC
CTCCGGCCCCCACCCAGTGCTGCACCGCAGGCCATCCTCTGTCACCCTTCCCTACAGCCTGAGGAGTACATGGCCTACGTTCAGAGGCAA
GCCGACTCAAAGCAGTATGGAGATAAAATCATAGAGGAGCTGCAAGATCTAGGCCCCCAAGTGTGGAGTGAGACCAAGTCTGGGGTGGCA
CCCCAAAAGATGGCAGGTGCGAGCCCGACCAAGGATGACAGTAAGGACTCAGATTTCTGGAAGATGCTTAATGAGCCAGAGGACCAGGCC
CCAGGAGGGGAGGAGGTGCCGGCTGAGGAGCAGGACCCAAGCCCTGAGGCAGCAGATTCAGCTTCTGGTGCTCCCAATGATTTTCAGAAC
AACGTGCAGGTCAAAGTCATTCGAAGCCCTGCGGATTTGATTCGATTCATAGAGGAGCTGAAAGGTGGAACAAAAAAGGGGAAGCCAAAT
ATAGGCCAAGAGCAGCCTGTGGATGATGCTGCAGAAGTCCCTCAGAGGGAACCAGAGAAGGAAAGGGGTGATCCAGAACGGCAGAGAGAG
ATGGAAGAAGAGGAGGATGAGGATGAGGATGAGGATGAAGATGAGGATGAACGGCAGTTACTGGGAGAATTTGAGAAGGAACTGGAAGGG
ATCCTGCTTCCGTCAGACCGAGACCGGCTCCGTTCGGAGGTGAAGGCTGGCATGGAGCGGGAACTGGAAAACATCATCCAGGAGACAGAG
AAAGAGCTGGACCCAGATGGGCTGAAGAAGGAGTCAGAGCGGGATCGGGCAATGCTGGCTCTCACATCCACTCTCAACAAACTCATCAAA
AGACTGGAGGAAAAACAGAGTCCAGAGCTGGTGAAGAAGCACAAGAAAAAGAGGGTTGTCCCCAAAAAGCCTCCCCCATCACCCCAACCT
ACAGGGAAAATTGAGATCAAAATTGTCCGCCCATGGGCTGAAGGGACTGAAGAGGGTGCACGTTGGCTGACTGATGAGGACACGAGAAAC
CTCAAGGAGATCTTCTTCAATATCTTGGTGCCGGGAGCTGAAGAGGCCCAGAAGGAACGCCAGCGGCAGAAAGAGCTGGAGAGCAATTAC
CGCCGGGTGTGGGGCTCTCCAGGTGGGGAGGGCACAGGGGACCTGGACGAATTTGACTTCTGAGACCAACACTACACTTGACCCTTCACG

>85192_85192_8_SORBS2-OS9_SORBS2_chr4_186578578_ENST00000393528_OS9_chr12_58109543_ENST00000552285_length(amino acids)=575AA_BP=156
MLNSAACRKTEDFNNKLSKVKMNTGRDSQSPDSAKGFRSVRPNLQDKRSPTQSQITVNGNSGGAVSPMSYYQRPFSPSAYSLPASLNSSI
VMQHGTSLDSTDTYPQHAQSLDGTTSSSIPLYRSSEEEKRVTVIKAPHYPGIGPVDESGIPTAIRTFLCDEGAGISGDYIDRVDEPLSCS
YVLTIRTPRLCPHPLLRPPPSAAPQAILCHPSLQPEEYMAYVQRQADSKQYGDKIIEELQDLGPQVWSETKSGVAPQKMAGASPTKDDSK
DSDFWKMLNEPEDQAPGGEEVPAEEQDPSPEAADSASGAPNDFQNNVQVKVIRSPADLIRFIEELKGGTKKGKPNIGQEQPVDDAAEVPQ
REPEKERGDPERQREMEEEEDEDEDEDEDEDERQLLGEFEKELEGILLPSDRDRLRSEVKAGMERELENIIQETEKELDPDGLKKESERD
RAMLALTSTLNKLIKRLEEKQSPELVKKHKKKRVVPKKPPPSPQPTGKIEIKIVRPWAEGTEEGARWLTDEDTRNLKEIFFNILVPGAEE

--------------------------------------------------------------

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Fusion Gene PPI Analysis for SORBS2-OS9


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for SORBS2-OS9


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for SORBS2-OS9


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource