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 | Fusion Gene Summary |
| Fusion Gene ORF analysis |
| Fusion Genomic Features |
| Fusion Protein Features |
| Fusion Gene Sequence |
| Fusion Gene PPI analysis |
| Related Drugs |
| Related Diseases |
Fusion gene:SOX5-IFLTD1 (FusionGDB2 ID:85328) |
Fusion Gene Summary for SOX5-IFLTD1 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: SOX5-IFLTD1 | Fusion gene ID: 85328 | Hgene | Tgene | Gene symbol | SOX5 | IFLTD1 | Gene ID | 6660 | 160492 |
| Gene name | SRY-box transcription factor 5 | lamin tail domain containing 1 | |
| Synonyms | L-SOX5|L-SOX5B|L-SOX5F|LAMSHF | IFLTD1|LMNARS1|PAS1C1 | |
| Cytomap | 12p12.1 | 12p12.1 | |
| Type of gene | protein-coding | protein-coding | |
| Description | transcription factor SOX-5SRY (sex determining region Y)-box 5SRY-box 5 | lamin tail domain-containing protein 1intermediate filament tail domain containing 1intermediate filament tail domain-containing protein 1 | |
| Modification date | 20200313 | 20200313 | |
| UniProtAcc | . | . | |
| Ensembl transtripts involved in fusion gene | ENST00000309359, ENST00000381381, ENST00000451604, ENST00000537393, ENST00000541536, ENST00000545921, ENST00000546136, ENST00000396007, ENST00000441133, ENST00000536850, ENST00000541847, | ENST00000458174, ENST00000539744, ENST00000413632, ENST00000445693, ENST00000282881, | |
| Fusion gene scores | * DoF score | 19 X 15 X 10=2850 | 8 X 5 X 5=200 |
| # samples | 19 | 8 | |
| ** MAII score | log2(19/2850*10)=-3.90689059560852 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(8/200*10)=-1.32192809488736 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: SOX5 [Title/Abstract] AND IFLTD1 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Most frequent breakpoint | SOX5(23793746)-IFLTD1(25702480), # samples:1 | ||
| Anticipated loss of major functional domain due to fusion event. | SOX5-IFLTD1 seems lost the major protein functional domain in Hgene partner, which is a transcription factor due to the frame-shifted ORF. | ||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Hgene | SOX5 | GO:0032332 | positive regulation of chondrocyte differentiation | 21401405 |
| Hgene | SOX5 | GO:0061036 | positive regulation of cartilage development | 21401405 |
| Hgene | SOX5 | GO:0071560 | cellular response to transforming growth factor beta stimulus | 21401405 |
| Hgene | SOX5 | GO:2000741 | positive regulation of mesenchymal stem cell differentiation | 21401405 |
| Fusion gene breakpoints across SOX5 (5'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
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| Fusion gene breakpoints across IFLTD1 (3'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
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| Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Source | Disease | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| ChimerDB4 | UCEC | TCGA-A5-A1OH-01A | SOX5 | chr12 | 23793746 | - | IFLTD1 | chr12 | 25702480 | - |
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Fusion Gene ORF analysis for SOX5-IFLTD1 |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| 5CDS-5UTR | ENST00000309359 | ENST00000458174 | SOX5 | chr12 | 23793746 | - | IFLTD1 | chr12 | 25702480 | - |
| 5CDS-5UTR | ENST00000309359 | ENST00000539744 | SOX5 | chr12 | 23793746 | - | IFLTD1 | chr12 | 25702480 | - |
| 5CDS-5UTR | ENST00000381381 | ENST00000458174 | SOX5 | chr12 | 23793746 | - | IFLTD1 | chr12 | 25702480 | - |
| 5CDS-5UTR | ENST00000381381 | ENST00000539744 | SOX5 | chr12 | 23793746 | - | IFLTD1 | chr12 | 25702480 | - |
| 5CDS-5UTR | ENST00000451604 | ENST00000458174 | SOX5 | chr12 | 23793746 | - | IFLTD1 | chr12 | 25702480 | - |
| 5CDS-5UTR | ENST00000451604 | ENST00000539744 | SOX5 | chr12 | 23793746 | - | IFLTD1 | chr12 | 25702480 | - |
| 5CDS-5UTR | ENST00000537393 | ENST00000458174 | SOX5 | chr12 | 23793746 | - | IFLTD1 | chr12 | 25702480 | - |
| 5CDS-5UTR | ENST00000537393 | ENST00000539744 | SOX5 | chr12 | 23793746 | - | IFLTD1 | chr12 | 25702480 | - |
| 5CDS-5UTR | ENST00000541536 | ENST00000458174 | SOX5 | chr12 | 23793746 | - | IFLTD1 | chr12 | 25702480 | - |
| 5CDS-5UTR | ENST00000541536 | ENST00000539744 | SOX5 | chr12 | 23793746 | - | IFLTD1 | chr12 | 25702480 | - |
| 5CDS-5UTR | ENST00000545921 | ENST00000458174 | SOX5 | chr12 | 23793746 | - | IFLTD1 | chr12 | 25702480 | - |
| 5CDS-5UTR | ENST00000545921 | ENST00000539744 | SOX5 | chr12 | 23793746 | - | IFLTD1 | chr12 | 25702480 | - |
| 5CDS-5UTR | ENST00000546136 | ENST00000458174 | SOX5 | chr12 | 23793746 | - | IFLTD1 | chr12 | 25702480 | - |
| 5CDS-5UTR | ENST00000546136 | ENST00000539744 | SOX5 | chr12 | 23793746 | - | IFLTD1 | chr12 | 25702480 | - |
| 5CDS-intron | ENST00000309359 | ENST00000413632 | SOX5 | chr12 | 23793746 | - | IFLTD1 | chr12 | 25702480 | - |
| 5CDS-intron | ENST00000309359 | ENST00000445693 | SOX5 | chr12 | 23793746 | - | IFLTD1 | chr12 | 25702480 | - |
| 5CDS-intron | ENST00000381381 | ENST00000413632 | SOX5 | chr12 | 23793746 | - | IFLTD1 | chr12 | 25702480 | - |
| 5CDS-intron | ENST00000381381 | ENST00000445693 | SOX5 | chr12 | 23793746 | - | IFLTD1 | chr12 | 25702480 | - |
| 5CDS-intron | ENST00000451604 | ENST00000413632 | SOX5 | chr12 | 23793746 | - | IFLTD1 | chr12 | 25702480 | - |
| 5CDS-intron | ENST00000451604 | ENST00000445693 | SOX5 | chr12 | 23793746 | - | IFLTD1 | chr12 | 25702480 | - |
| 5CDS-intron | ENST00000537393 | ENST00000413632 | SOX5 | chr12 | 23793746 | - | IFLTD1 | chr12 | 25702480 | - |
| 5CDS-intron | ENST00000537393 | ENST00000445693 | SOX5 | chr12 | 23793746 | - | IFLTD1 | chr12 | 25702480 | - |
| 5CDS-intron | ENST00000541536 | ENST00000413632 | SOX5 | chr12 | 23793746 | - | IFLTD1 | chr12 | 25702480 | - |
| 5CDS-intron | ENST00000541536 | ENST00000445693 | SOX5 | chr12 | 23793746 | - | IFLTD1 | chr12 | 25702480 | - |
| 5CDS-intron | ENST00000545921 | ENST00000413632 | SOX5 | chr12 | 23793746 | - | IFLTD1 | chr12 | 25702480 | - |
| 5CDS-intron | ENST00000545921 | ENST00000445693 | SOX5 | chr12 | 23793746 | - | IFLTD1 | chr12 | 25702480 | - |
| 5CDS-intron | ENST00000546136 | ENST00000413632 | SOX5 | chr12 | 23793746 | - | IFLTD1 | chr12 | 25702480 | - |
| 5CDS-intron | ENST00000546136 | ENST00000445693 | SOX5 | chr12 | 23793746 | - | IFLTD1 | chr12 | 25702480 | - |
| Frame-shift | ENST00000309359 | ENST00000282881 | SOX5 | chr12 | 23793746 | - | IFLTD1 | chr12 | 25702480 | - |
| Frame-shift | ENST00000381381 | ENST00000282881 | SOX5 | chr12 | 23793746 | - | IFLTD1 | chr12 | 25702480 | - |
| In-frame | ENST00000451604 | ENST00000282881 | SOX5 | chr12 | 23793746 | - | IFLTD1 | chr12 | 25702480 | - |
| In-frame | ENST00000537393 | ENST00000282881 | SOX5 | chr12 | 23793746 | - | IFLTD1 | chr12 | 25702480 | - |
| In-frame | ENST00000541536 | ENST00000282881 | SOX5 | chr12 | 23793746 | - | IFLTD1 | chr12 | 25702480 | - |
| In-frame | ENST00000545921 | ENST00000282881 | SOX5 | chr12 | 23793746 | - | IFLTD1 | chr12 | 25702480 | - |
| In-frame | ENST00000546136 | ENST00000282881 | SOX5 | chr12 | 23793746 | - | IFLTD1 | chr12 | 25702480 | - |
| intron-3CDS | ENST00000396007 | ENST00000282881 | SOX5 | chr12 | 23793746 | - | IFLTD1 | chr12 | 25702480 | - |
| intron-3CDS | ENST00000441133 | ENST00000282881 | SOX5 | chr12 | 23793746 | - | IFLTD1 | chr12 | 25702480 | - |
| intron-3CDS | ENST00000536850 | ENST00000282881 | SOX5 | chr12 | 23793746 | - | IFLTD1 | chr12 | 25702480 | - |
| intron-3CDS | ENST00000541847 | ENST00000282881 | SOX5 | chr12 | 23793746 | - | IFLTD1 | chr12 | 25702480 | - |
| intron-5UTR | ENST00000396007 | ENST00000458174 | SOX5 | chr12 | 23793746 | - | IFLTD1 | chr12 | 25702480 | - |
| intron-5UTR | ENST00000396007 | ENST00000539744 | SOX5 | chr12 | 23793746 | - | IFLTD1 | chr12 | 25702480 | - |
| intron-5UTR | ENST00000441133 | ENST00000458174 | SOX5 | chr12 | 23793746 | - | IFLTD1 | chr12 | 25702480 | - |
| intron-5UTR | ENST00000441133 | ENST00000539744 | SOX5 | chr12 | 23793746 | - | IFLTD1 | chr12 | 25702480 | - |
| intron-5UTR | ENST00000536850 | ENST00000458174 | SOX5 | chr12 | 23793746 | - | IFLTD1 | chr12 | 25702480 | - |
| intron-5UTR | ENST00000536850 | ENST00000539744 | SOX5 | chr12 | 23793746 | - | IFLTD1 | chr12 | 25702480 | - |
| intron-5UTR | ENST00000541847 | ENST00000458174 | SOX5 | chr12 | 23793746 | - | IFLTD1 | chr12 | 25702480 | - |
| intron-5UTR | ENST00000541847 | ENST00000539744 | SOX5 | chr12 | 23793746 | - | IFLTD1 | chr12 | 25702480 | - |
| intron-intron | ENST00000396007 | ENST00000413632 | SOX5 | chr12 | 23793746 | - | IFLTD1 | chr12 | 25702480 | - |
| intron-intron | ENST00000396007 | ENST00000445693 | SOX5 | chr12 | 23793746 | - | IFLTD1 | chr12 | 25702480 | - |
| intron-intron | ENST00000441133 | ENST00000413632 | SOX5 | chr12 | 23793746 | - | IFLTD1 | chr12 | 25702480 | - |
| intron-intron | ENST00000441133 | ENST00000445693 | SOX5 | chr12 | 23793746 | - | IFLTD1 | chr12 | 25702480 | - |
| intron-intron | ENST00000536850 | ENST00000413632 | SOX5 | chr12 | 23793746 | - | IFLTD1 | chr12 | 25702480 | - |
| intron-intron | ENST00000536850 | ENST00000445693 | SOX5 | chr12 | 23793746 | - | IFLTD1 | chr12 | 25702480 | - |
| intron-intron | ENST00000541847 | ENST00000413632 | SOX5 | chr12 | 23793746 | - | IFLTD1 | chr12 | 25702480 | - |
| intron-intron | ENST00000541847 | ENST00000445693 | SOX5 | chr12 | 23793746 | - | IFLTD1 | chr12 | 25702480 | - |
| ORFfinder result based on the fusion transcript sequence of in-frame fusion genes. |
| Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | Seq length (transcript) | BP loci (transcript) | Predicted start (transcript) | Predicted stop (transcript) | Seq length (amino acids) |
| ENST00000546136 | SOX5 | chr12 | 23793746 | - | ENST00000282881 | IFLTD1 | chr12 | 25702480 | - | 2523 | 981 | 3 | 1109 | 368 |
| ENST00000451604 | SOX5 | chr12 | 23793746 | - | ENST00000282881 | IFLTD1 | chr12 | 25702480 | - | 2661 | 1119 | 48 | 1247 | 399 |
| ENST00000537393 | SOX5 | chr12 | 23793746 | - | ENST00000282881 | IFLTD1 | chr12 | 25702480 | - | 2500 | 958 | 1007 | 2098 | 363 |
| ENST00000541536 | SOX5 | chr12 | 23793746 | - | ENST00000282881 | IFLTD1 | chr12 | 25702480 | - | 2524 | 982 | 4 | 1110 | 368 |
| ENST00000545921 | SOX5 | chr12 | 23793746 | - | ENST00000282881 | IFLTD1 | chr12 | 25702480 | - | 2685 | 1143 | 156 | 1271 | 371 |
| DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated. |
| Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | No-coding score | Coding score |
| ENST00000546136 | ENST00000282881 | SOX5 | chr12 | 23793746 | - | IFLTD1 | chr12 | 25702480 | - | 0.006991493 | 0.9930085 |
| ENST00000451604 | ENST00000282881 | SOX5 | chr12 | 23793746 | - | IFLTD1 | chr12 | 25702480 | - | 0.011254941 | 0.98874503 |
| ENST00000537393 | ENST00000282881 | SOX5 | chr12 | 23793746 | - | IFLTD1 | chr12 | 25702480 | - | 0.01158198 | 0.98841804 |
| ENST00000541536 | ENST00000282881 | SOX5 | chr12 | 23793746 | - | IFLTD1 | chr12 | 25702480 | - | 0.007011622 | 0.9929884 |
| ENST00000545921 | ENST00000282881 | SOX5 | chr12 | 23793746 | - | IFLTD1 | chr12 | 25702480 | - | 0.011116247 | 0.98888373 |
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Fusion Genomic Features for SOX5-IFLTD1 |
| FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints. |
| Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | 1-p | p (fusion gene breakpoint) |
| Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page. |
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| Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page. |
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Fusion Protein Features for SOX5-IFLTD1 |
| Four levels of functional features of fusion genes Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr12:23793746/chr12:25702480) - FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels. - How to search 1. Put your fusion gene symbol. 2. Press the tab key until there will be shown the breakpoint information filled. 4. Go down and press 'Search' tab twice. 4. Go down to have the hyperlink of the search result. 5. Click the hyperlink. 6. See the FGviewer result for your fusion gene. |
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| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| . | . |
| FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}. | FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | SOX5 | chr12:23793746 | chr12:25702480 | ENST00000309359 | - | 8 | 15 | 193_274 | 326 | 751.0 | Coiled coil | Ontology_term=ECO:0000255 |
| Hgene | SOX5 | chr12:23793746 | chr12:25702480 | ENST00000381381 | - | 8 | 13 | 193_274 | 326 | 643.0 | Coiled coil | Ontology_term=ECO:0000255 |
| Hgene | SOX5 | chr12:23793746 | chr12:25702480 | ENST00000451604 | - | 8 | 15 | 193_274 | 339 | 764.0 | Coiled coil | Ontology_term=ECO:0000255 |
| Hgene | SOX5 | chr12:23793746 | chr12:25702480 | ENST00000541536 | - | 7 | 12 | 193_274 | 326 | 643.0 | Coiled coil | Ontology_term=ECO:0000255 |
| Hgene | SOX5 | chr12:23793746 | chr12:25702480 | ENST00000545921 | - | 8 | 15 | 193_274 | 329 | 754.0 | Coiled coil | Ontology_term=ECO:0000255 |
| Hgene | SOX5 | chr12:23793746 | chr12:25702480 | ENST00000546136 | - | 7 | 14 | 193_274 | 326 | 751.0 | Coiled coil | Ontology_term=ECO:0000255 |
| Tgene | IFLTD1 | chr12:23793746 | chr12:25702480 | ENST00000282881 | 0 | 9 | 136_254 | 8 | 404.0 | Domain | LTD | |
| Tgene | IFLTD1 | chr12:23793746 | chr12:25702480 | ENST00000413632 | 1 | 9 | 136_254 | 29 | 328.6666666666667 | Domain | LTD | |
| Tgene | IFLTD1 | chr12:23793746 | chr12:25702480 | ENST00000445693 | 0 | 8 | 136_254 | 0 | 360.3333333333333 | Domain | LTD | |
| Tgene | IFLTD1 | chr12:23793746 | chr12:25702480 | ENST00000458174 | 1 | 10 | 136_254 | 29 | 379.6666666666667 | Domain | LTD | |
| Tgene | IFLTD1 | chr12:23793746 | chr12:25702480 | ENST00000539744 | 0 | 10 | 136_254 | 0 | 327.0 | Domain | LTD |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | SOX5 | chr12:23793746 | chr12:25702480 | ENST00000309359 | - | 8 | 15 | 448_515 | 326 | 751.0 | Coiled coil | Ontology_term=ECO:0000255 |
| Hgene | SOX5 | chr12:23793746 | chr12:25702480 | ENST00000381381 | - | 8 | 13 | 448_515 | 326 | 643.0 | Coiled coil | Ontology_term=ECO:0000255 |
| Hgene | SOX5 | chr12:23793746 | chr12:25702480 | ENST00000396007 | - | 1 | 7 | 193_274 | 0 | 378.0 | Coiled coil | Ontology_term=ECO:0000255 |
| Hgene | SOX5 | chr12:23793746 | chr12:25702480 | ENST00000396007 | - | 1 | 7 | 448_515 | 0 | 378.0 | Coiled coil | Ontology_term=ECO:0000255 |
| Hgene | SOX5 | chr12:23793746 | chr12:25702480 | ENST00000451604 | - | 8 | 15 | 448_515 | 339 | 764.0 | Coiled coil | Ontology_term=ECO:0000255 |
| Hgene | SOX5 | chr12:23793746 | chr12:25702480 | ENST00000541536 | - | 7 | 12 | 448_515 | 326 | 643.0 | Coiled coil | Ontology_term=ECO:0000255 |
| Hgene | SOX5 | chr12:23793746 | chr12:25702480 | ENST00000545921 | - | 8 | 15 | 448_515 | 329 | 754.0 | Coiled coil | Ontology_term=ECO:0000255 |
| Hgene | SOX5 | chr12:23793746 | chr12:25702480 | ENST00000546136 | - | 7 | 14 | 448_515 | 326 | 751.0 | Coiled coil | Ontology_term=ECO:0000255 |
| Hgene | SOX5 | chr12:23793746 | chr12:25702480 | ENST00000309359 | - | 8 | 15 | 556_624 | 326 | 751.0 | DNA binding | HMG box |
| Hgene | SOX5 | chr12:23793746 | chr12:25702480 | ENST00000381381 | - | 8 | 13 | 556_624 | 326 | 643.0 | DNA binding | HMG box |
| Hgene | SOX5 | chr12:23793746 | chr12:25702480 | ENST00000396007 | - | 1 | 7 | 556_624 | 0 | 378.0 | DNA binding | HMG box |
| Hgene | SOX5 | chr12:23793746 | chr12:25702480 | ENST00000451604 | - | 8 | 15 | 556_624 | 339 | 764.0 | DNA binding | HMG box |
| Hgene | SOX5 | chr12:23793746 | chr12:25702480 | ENST00000541536 | - | 7 | 12 | 556_624 | 326 | 643.0 | DNA binding | HMG box |
| Hgene | SOX5 | chr12:23793746 | chr12:25702480 | ENST00000545921 | - | 8 | 15 | 556_624 | 329 | 754.0 | DNA binding | HMG box |
| Hgene | SOX5 | chr12:23793746 | chr12:25702480 | ENST00000546136 | - | 7 | 14 | 556_624 | 326 | 751.0 | DNA binding | HMG box |
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Fusion Gene Sequence for SOX5-IFLTD1 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones. |
| >85328_85328_1_SOX5-IFLTD1_SOX5_chr12_23793746_ENST00000451604_IFLTD1_chr12_25702480_ENST00000282881_length(transcript)=2661nt_BP=1119nt GAGAAAATCAATTGGTTTAGAAGGTTTGGACTCACTTGACAGGTTCAGTTGGAGACGATCATAGGTGGCTGCTGTGACAAAGGGAAATTG TGCTTTTCCAGCATGCTTACTGACCCTGATTTACCTCAGGAGTTTGAAAGGATGTCTTCCAAGCGACCAGCCTCTCCGTATGGGGAAGCA GATGGAGAGGTAGCCATGGTGACAAGCAGACAGAAAGTGGAAGAAGAGGAGAGTGACGGGCTCCCAGCCTTTCACCTTCCCTTGCATGTG AGTTTTCCCAACAAGCCTCACTCTGAGGAATTTCAGCCAGTTTCTCTGCTGACGCAAGAGACTTGTGGCCATAGGACTCCCACTTCTCAG CACAATACAATGGAAGTTGATGGCAATAAAGTTATGTCTTCATTTGCCCCACACAACTCATCTACCTCACCTCAGAAGGCAGAAGAAGGT GGGCGACAGAGTGGCGAGTCCTTGTCTAGTACAGCCCTGGGAACTCCTGAACGGCGCAAGGGCAGTTTAGCTGATGTTGTTGACACCTTG AAGCAGAGGAAAATGGAAGAGCTCATCAAAAACGAGCCGGAAGAAACCCCCAGTATTGAAAAACTACTCTCAAAGGACTGGAAAGACAAG CTTCTTGCAATGGGATCGGGGAACTTTGGCGAAATAAAAGGGACTCCCGAGAGCTTAGCTGAGAAAGAAAGGCAACTCATGGGTATGATC AACCAGCTGACCAGCCTCCGAGAGCAGCTGTTGGCTGCCCACGATGAGCAGAAGAAACTAGCTGCCTCTCAGATTGAGAAACAGCGTCAG CAAATGGAGCTGGCCAAGCAGCAACAAGAACAAATTGCAAGACAGCAGCAGCAGCTTCTACAGCAACAACACAAAATCAATTTGCTCCAG CAACAGATCCAGGTTCAAGGTCAGCTGCCGCCATTAATGATTCCCGTATTCCCTCCTGATCAACGGACACTGGCTGCAGCTGCCCAGCAA GGATTCCTCCTCCCTCCAGGCTTCAGCTATAAGGCTGGATGTAGTGACCCTTACCCTGTTCAGCTGATCCCAACTACCATGGCAGCTGCT GCCGCAGCAACACCAGGCTTAGGCCCACTCCAACTGCAGAAGAGAAGACAAACTTGGAGTATATTCTTTAGTACATTTTTCCCCAAAGAT GTTGGGTTCAGTTGCCACAACACTGCCATTGTCATCTTCAAATTCCAGTGGAATGCCTCTTGGTTACTATCTGTCTAGTCCTCAGATTAG TAGAGTAACTATATCAACAACTGGACAATTGACTTCTAAAGCTACTGTAGGTAGCTGTTCCAGAGTGGAAAACAGCTTGGATGCCAGCCC CTTCTCAGTTCCGAAGAAACAGGATGAATCACCCATGATTGGGGATGGAGAAGATTATTTCCTTTCTTTGTTTGGTGATTCAAAGAAACT TACAGCACACTCAAACTACACTCAGAAAACTTTAAAATACTTTTCTATGATTCTTGAAGAAGTTGGCCAATTTACCTCCAGTTCTCTTGG AGATGTTGAAATAGCTGAAGTGAATGTCAAGGGTTTGTTCGTGAAGCTCATTAACTCTTCCCTTGACAAAGAAATGGCAATTGGAGATCA TATTCTCCAGCAAAATGTGAATGGACAAACCATTTCTTTGTACCGATTCCTTCCAAACATCGTAATGCAGGCAAATTCCACAGTAACAGT GTGGGCAGCAGCATCTGAAGCAAAGCATCAACCTCCATCAGATTTTCTTTGGAAGGAACAAGACAAGTTTAGAGCAAGTCCTGATTGTAT AACAATCCTGTGCAAACCGAACGGTCAAGCCATTGCGTGGTACACCCCTATCCACTGGAAGCAAGCGTGGGAAAAATTAGATGCTGACGT TGAATTTAACAGATGTTCAGTAGTATCTCCAACATTCCGAAAGCGTGTGTTTCAGTGGACAGCATCTACAGCTACAATAACTAAAGAAAA ACAAGATCAACCTAAGAAAGATATCTCAAATTATCAGGTGGAACAAGCTCAAGTTCTTCTTAAGAGAGAGAAGGAAATCCCACCAACCGT TTTCCCTAATCGCAGCCCTTGGTGCCAGAATCCCTATGTCTCTGCACATCCTTACTGTCCTCTGATTGAACCACACAATACATCCACCGC TGGAGGCAGATTGGATAGACAGCCCAGGACTCGGTCAACCAGACCTAATCGAGCCTCAGGGTCTAAGAAAAAGAAGACATCTGAGTCACA AAAGCAATAAGCAGTCAACTCAACCTTTAAAGTAATCTAGTCCACCCTCAACCAGCTACTAGAAAAGCAAAAGAGAACTCAAATCCCTGA GGCCTGCTCTGCAACCTCCCTGCTATTCCATGAGAGGGTGAAGACATCACATTTCTATATGGAAAAAGGATCCAAAATTTGTATTGCTGT AGAATTGGTGAATTATAGATGCTTGATGAAATCACAAGTCCTACCACTCCTGCCTTCCAAATCCCTGCAGAAAACAAGCAGATGGTTAGT ATTATTCAATGGATAAAATTGCTATTTGCCTTAGATTTCTCTTTTTGTAAACAAAGTTATTTTGGGTACAGAACTCACAAAAGAAGAGCA >85328_85328_1_SOX5-IFLTD1_SOX5_chr12_23793746_ENST00000451604_IFLTD1_chr12_25702480_ENST00000282881_length(amino acids)=399AA_BP=351 METIIGGCCDKGKLCFSSMLTDPDLPQEFERMSSKRPASPYGEADGEVAMVTSRQKVEEEESDGLPAFHLPLHVSFPNKPHSEEFQPVSL LTQETCGHRTPTSQHNTMEVDGNKVMSSFAPHNSSTSPQKAEEGGRQSGESLSSTALGTPERRKGSLADVVDTLKQRKMEELIKNEPEET PSIEKLLSKDWKDKLLAMGSGNFGEIKGTPESLAEKERQLMGMINQLTSLREQLLAAHDEQKKLAASQIEKQRQQMELAKQQQEQIARQQ QQLLQQQHKINLLQQQIQVQGQLPPLMIPVFPPDQRTLAAAAQQGFLLPPGFSYKAGCSDPYPVQLIPTTMAAAAAATPGLGPLQLQKRR -------------------------------------------------------------- >85328_85328_2_SOX5-IFLTD1_SOX5_chr12_23793746_ENST00000537393_IFLTD1_chr12_25702480_ENST00000282881_length(transcript)=2500nt_BP=958nt GATCATAGGTGGCTGCTGTGACAAAGGGAAATTGTGCTTTTCCAGCATGCTTACTGACCCTGATTTACCTCAGGAGTTTGAAAGGATGTC TTCCAAGCGACCAGCCTCTCCGTATGGGGAAGCAGATGGAGAGGTAGCCATGGTGACAAGCAGACAGAAAGTGGAAGAAGAGGAGAGTGA CGGGCTCCCAGCCTTTCACCTTCCCTTGCATGAAGTTGATGGCAATAAAGTTATGTCTTCATTTGCCCCACACAACTCATCTACCTCACC TCAGAAGGCAGAAGAAGGTGGGCGACAGAGTGGCGAGTCCTTGTCTAGTACAGCCCTGGGAACTCCTGAACGGCGCAAGGGCAGTTTAGC TGATGTTGTTGACACCTTGAAGCAGAGGAAAATGGAAGAGCTCATCAAAAACGAGCCGGAAGAAACCCCCAGTATTGAAAAACTACTCTC AAAGGACTGGAAAGACAAGCTTCTTGCAATGGGATCGGGGAACTTTGGCGAAATAAAAGGGACTCCCGAGAGCTTAGCTGAGAAAGAAAG GCAACTCATGGGTATGATCAACCAGCTGACCAGCCTCCGAGAGCAGCTGTTGGCTGCCCACGATGAGCAGAAGAAACTAGCTGCCTCTCA GATTGAGAAACAGCGTCAGCAAATGGAGCTGGCCAAGCAGCAACAAGAACAAATTGCAAGACAGCAGCAGCAGCTTCTACAGCAACAACA CAAAATCAATTTGCTCCAGCAACAGATCCAGGTTCAAGGTCAGCTGCCGCCATTAATGATTCCCGTATTCCCTCCTGATCAACGGACACT GGCTGCAGCTGCCCAGCAAGGATTCCTCCTCCCTCCAGGCTTCAGCTATAAGGCTGGATGTAGTGACCCTTACCCTGTTCAGCTGATCCC AACTACCATGGCAGCTGCTGCCGCAGCAACACCAGGCTTAGGCCCACTCCAACTGCAGAAGAGAAGACAAACTTGGAGTATATTCTTTAG TACATTTTTCCCCAAAGATGTTGGGTTCAGTTGCCACAACACTGCCATTGTCATCTTCAAATTCCAGTGGAATGCCTCTTGGTTACTATC TGTCTAGTCCTCAGATTAGTAGAGTAACTATATCAACAACTGGACAATTGACTTCTAAAGCTACTGTAGGTAGCTGTTCCAGAGTGGAAA ACAGCTTGGATGCCAGCCCCTTCTCAGTTCCGAAGAAACAGGATGAATCACCCATGATTGGGGATGGAGAAGATTATTTCCTTTCTTTGT TTGGTGATTCAAAGAAACTTACAGCACACTCAAACTACACTCAGAAAACTTTAAAATACTTTTCTATGATTCTTGAAGAAGTTGGCCAAT TTACCTCCAGTTCTCTTGGAGATGTTGAAATAGCTGAAGTGAATGTCAAGGGTTTGTTCGTGAAGCTCATTAACTCTTCCCTTGACAAAG AAATGGCAATTGGAGATCATATTCTCCAGCAAAATGTGAATGGACAAACCATTTCTTTGTACCGATTCCTTCCAAACATCGTAATGCAGG CAAATTCCACAGTAACAGTGTGGGCAGCAGCATCTGAAGCAAAGCATCAACCTCCATCAGATTTTCTTTGGAAGGAACAAGACAAGTTTA GAGCAAGTCCTGATTGTATAACAATCCTGTGCAAACCGAACGGTCAAGCCATTGCGTGGTACACCCCTATCCACTGGAAGCAAGCGTGGG AAAAATTAGATGCTGACGTTGAATTTAACAGATGTTCAGTAGTATCTCCAACATTCCGAAAGCGTGTGTTTCAGTGGACAGCATCTACAG CTACAATAACTAAAGAAAAACAAGATCAACCTAAGAAAGATATCTCAAATTATCAGGTGGAACAAGCTCAAGTTCTTCTTAAGAGAGAGA AGGAAATCCCACCAACCGTTTTCCCTAATCGCAGCCCTTGGTGCCAGAATCCCTATGTCTCTGCACATCCTTACTGTCCTCTGATTGAAC CACACAATACATCCACCGCTGGAGGCAGATTGGATAGACAGCCCAGGACTCGGTCAACCAGACCTAATCGAGCCTCAGGGTCTAAGAAAA AGAAGACATCTGAGTCACAAAAGCAATAAGCAGTCAACTCAACCTTTAAAGTAATCTAGTCCACCCTCAACCAGCTACTAGAAAAGCAAA AGAGAACTCAAATCCCTGAGGCCTGCTCTGCAACCTCCCTGCTATTCCATGAGAGGGTGAAGACATCACATTTCTATATGGAAAAAGGAT CCAAAATTTGTATTGCTGTAGAATTGGTGAATTATAGATGCTTGATGAAATCACAAGTCCTACCACTCCTGCCTTCCAAATCCCTGCAGA AAACAAGCAGATGGTTAGTATTATTCAATGGATAAAATTGCTATTTGCCTTAGATTTCTCTTTTTGTAAACAAAGTTATTTTGGGTACAG >85328_85328_2_SOX5-IFLTD1_SOX5_chr12_23793746_ENST00000537393_IFLTD1_chr12_25702480_ENST00000282881_length(amino acids)=363AA_BP= MLGSVATTLPLSSSNSSGMPLGYYLSSPQISRVTISTTGQLTSKATVGSCSRVENSLDASPFSVPKKQDESPMIGDGEDYFLSLFGDSKK LTAHSNYTQKTLKYFSMILEEVGQFTSSSLGDVEIAEVNVKGLFVKLINSSLDKEMAIGDHILQQNVNGQTISLYRFLPNIVMQANSTVT VWAAASEAKHQPPSDFLWKEQDKFRASPDCITILCKPNGQAIAWYTPIHWKQAWEKLDADVEFNRCSVVSPTFRKRVFQWTASTATITKE KQDQPKKDISNYQVEQAQVLLKREKEIPPTVFPNRSPWCQNPYVSAHPYCPLIEPHNTSTAGGRLDRQPRTRSTRPNRASGSKKKKTSES -------------------------------------------------------------- >85328_85328_3_SOX5-IFLTD1_SOX5_chr12_23793746_ENST00000541536_IFLTD1_chr12_25702480_ENST00000282881_length(transcript)=2524nt_BP=982nt CAGGATGTCTTCCAAGCGACCAGCCTCTCCGTATGGGGAAGCAGATGGAGAGGTAGCCATGGTGACAAGCAGACAGAAAGTGGAAGAAGA GGAGAGTGACGGGCTCCCAGCCTTTCACCTTCCCTTGCATGTGAGTTTTCCCAACAAGCCTCACTCTGAGGAATTTCAGCCAGTTTCTCT GCTGACGCAAGAGACTTGTGGCCATAGGACTCCCACTTCTCAGCACAATACAATGGAAGTTGATGGCAATAAAGTTATGTCTTCATTTGC CCCACACAACTCATCTACCTCACCTCAGAAGGCAGAAGAAGGTGGGCGACAGAGTGGCGAGTCCTTGTCTAGTACAGCCCTGGGAACTCC TGAACGGCGCAAGGGCAGTTTAGCTGATGTTGTTGACACCTTGAAGCAGAGGAAAATGGAAGAGCTCATCAAAAACGAGCCGGAAGAAAC CCCCAGTATTGAAAAACTACTCTCAAAGGACTGGAAAGACAAGCTTCTTGCAATGGGATCGGGGAACTTTGGCGAAATAAAAGGGACTCC CGAGAGCTTAGCTGAGAAAGAAAGGCAACTCATGGGTATGATCAACCAGCTGACCAGCCTCCGAGAGCAGCTGTTGGCTGCCCACGATGA GCAGAAGAAACTAGCTGCCTCTCAGATTGAGAAACAGCGTCAGCAAATGGAGCTGGCCAAGCAGCAACAAGAACAAATTGCAAGACAGCA GCAGCAGCTTCTACAGCAACAACACAAAATCAATTTGCTCCAGCAACAGATCCAGGTTCAAGGTCAGCTGCCGCCATTAATGATTCCCGT ATTCCCTCCTGATCAACGGACACTGGCTGCAGCTGCCCAGCAAGGATTCCTCCTCCCTCCAGGCTTCAGCTATAAGGCTGGATGTAGTGA CCCTTACCCTGTTCAGCTGATCCCAACTACCATGGCAGCTGCTGCCGCAGCAACACCAGGCTTAGGCCCACTCCAACTGCAGAAGAGAAG ACAAACTTGGAGTATATTCTTTAGTACATTTTTCCCCAAAGATGTTGGGTTCAGTTGCCACAACACTGCCATTGTCATCTTCAAATTCCA GTGGAATGCCTCTTGGTTACTATCTGTCTAGTCCTCAGATTAGTAGAGTAACTATATCAACAACTGGACAATTGACTTCTAAAGCTACTG TAGGTAGCTGTTCCAGAGTGGAAAACAGCTTGGATGCCAGCCCCTTCTCAGTTCCGAAGAAACAGGATGAATCACCCATGATTGGGGATG GAGAAGATTATTTCCTTTCTTTGTTTGGTGATTCAAAGAAACTTACAGCACACTCAAACTACACTCAGAAAACTTTAAAATACTTTTCTA TGATTCTTGAAGAAGTTGGCCAATTTACCTCCAGTTCTCTTGGAGATGTTGAAATAGCTGAAGTGAATGTCAAGGGTTTGTTCGTGAAGC TCATTAACTCTTCCCTTGACAAAGAAATGGCAATTGGAGATCATATTCTCCAGCAAAATGTGAATGGACAAACCATTTCTTTGTACCGAT TCCTTCCAAACATCGTAATGCAGGCAAATTCCACAGTAACAGTGTGGGCAGCAGCATCTGAAGCAAAGCATCAACCTCCATCAGATTTTC TTTGGAAGGAACAAGACAAGTTTAGAGCAAGTCCTGATTGTATAACAATCCTGTGCAAACCGAACGGTCAAGCCATTGCGTGGTACACCC CTATCCACTGGAAGCAAGCGTGGGAAAAATTAGATGCTGACGTTGAATTTAACAGATGTTCAGTAGTATCTCCAACATTCCGAAAGCGTG TGTTTCAGTGGACAGCATCTACAGCTACAATAACTAAAGAAAAACAAGATCAACCTAAGAAAGATATCTCAAATTATCAGGTGGAACAAG CTCAAGTTCTTCTTAAGAGAGAGAAGGAAATCCCACCAACCGTTTTCCCTAATCGCAGCCCTTGGTGCCAGAATCCCTATGTCTCTGCAC ATCCTTACTGTCCTCTGATTGAACCACACAATACATCCACCGCTGGAGGCAGATTGGATAGACAGCCCAGGACTCGGTCAACCAGACCTA ATCGAGCCTCAGGGTCTAAGAAAAAGAAGACATCTGAGTCACAAAAGCAATAAGCAGTCAACTCAACCTTTAAAGTAATCTAGTCCACCC TCAACCAGCTACTAGAAAAGCAAAAGAGAACTCAAATCCCTGAGGCCTGCTCTGCAACCTCCCTGCTATTCCATGAGAGGGTGAAGACAT CACATTTCTATATGGAAAAAGGATCCAAAATTTGTATTGCTGTAGAATTGGTGAATTATAGATGCTTGATGAAATCACAAGTCCTACCAC TCCTGCCTTCCAAATCCCTGCAGAAAACAAGCAGATGGTTAGTATTATTCAATGGATAAAATTGCTATTTGCCTTAGATTTCTCTTTTTG TAAACAAAGTTATTTTGGGTACAGAACTCACAAAAGAAGAGCACGTGCAATTGTTTAACCATTTTACATTGACTGATAAATCTCTTTTTT >85328_85328_3_SOX5-IFLTD1_SOX5_chr12_23793746_ENST00000541536_IFLTD1_chr12_25702480_ENST00000282881_length(amino acids)=368AA_BP=320 MSSKRPASPYGEADGEVAMVTSRQKVEEEESDGLPAFHLPLHVSFPNKPHSEEFQPVSLLTQETCGHRTPTSQHNTMEVDGNKVMSSFAP HNSSTSPQKAEEGGRQSGESLSSTALGTPERRKGSLADVVDTLKQRKMEELIKNEPEETPSIEKLLSKDWKDKLLAMGSGNFGEIKGTPE SLAEKERQLMGMINQLTSLREQLLAAHDEQKKLAASQIEKQRQQMELAKQQQEQIARQQQQLLQQQHKINLLQQQIQVQGQLPPLMIPVF PPDQRTLAAAAQQGFLLPPGFSYKAGCSDPYPVQLIPTTMAAAAAATPGLGPLQLQKRRQTWSIFFSTFFPKDVGFSCHNTAIVIFKFQW -------------------------------------------------------------- >85328_85328_4_SOX5-IFLTD1_SOX5_chr12_23793746_ENST00000545921_IFLTD1_chr12_25702480_ENST00000282881_length(transcript)=2685nt_BP=1143nt AGTAGGAGTGGAGAGCGTGCGTGAGTGAGTGTGTGTGTGTGTGTGTGTGTGTGTGCATGCGTGTGTGAAGAATGCACACTATCTCCTGTT GGTAAGTGTGTGCTTACTCCCTGACCAGATGCTGCGGTGCACGGGGCAGCCACCATCTCTGCATGCATGTCTGTGATGTCTTCCAAGCGA CCAGCCTCTCCGTATGGGGAAGCAGATGGAGAGGTAGCCATGGTGACAAGCAGACAGAAAGTGGAAGAAGAGGAGAGTGACGGGCTCCCA GCCTTTCACCTTCCCTTGCATGTGAGTTTTCCCAACAAGCCTCACTCTGAGGAATTTCAGCCAGTTTCTCTGCTGACGCAAGAGACTTGT GGCCATAGGACTCCCACTTCTCAGCACAATACAATGGAAGTTGATGGCAATAAAGTTATGTCTTCATTTGCCCCACACAACTCATCTACC TCACCTCAGAAGGCAGAAGAAGGTGGGCGACAGAGTGGCGAGTCCTTGTCTAGTACAGCCCTGGGAACTCCTGAACGGCGCAAGGGCAGT TTAGCTGATGTTGTTGACACCTTGAAGCAGAGGAAAATGGAAGAGCTCATCAAAAACGAGCCGGAAGAAACCCCCAGTATTGAAAAACTA CTCTCAAAGGACTGGAAAGACAAGCTTCTTGCAATGGGATCGGGGAACTTTGGCGAAATAAAAGGGACTCCCGAGAGCTTAGCTGAGAAA GAAAGGCAACTCATGGGTATGATCAACCAGCTGACCAGCCTCCGAGAGCAGCTGTTGGCTGCCCACGATGAGCAGAAGAAACTAGCTGCC TCTCAGATTGAGAAACAGCGTCAGCAAATGGAGCTGGCCAAGCAGCAACAAGAACAAATTGCAAGACAGCAGCAGCAGCTTCTACAGCAA CAACACAAAATCAATTTGCTCCAGCAACAGATCCAGGTTCAAGGTCAGCTGCCGCCATTAATGATTCCCGTATTCCCTCCTGATCAACGG ACACTGGCTGCAGCTGCCCAGCAAGGATTCCTCCTCCCTCCAGGCTTCAGCTATAAGGCTGGATGTAGTGACCCTTACCCTGTTCAGCTG ATCCCAACTACCATGGCAGCTGCTGCCGCAGCAACACCAGGCTTAGGCCCACTCCAACTGCAGAAGAGAAGACAAACTTGGAGTATATTC TTTAGTACATTTTTCCCCAAAGATGTTGGGTTCAGTTGCCACAACACTGCCATTGTCATCTTCAAATTCCAGTGGAATGCCTCTTGGTTA CTATCTGTCTAGTCCTCAGATTAGTAGAGTAACTATATCAACAACTGGACAATTGACTTCTAAAGCTACTGTAGGTAGCTGTTCCAGAGT GGAAAACAGCTTGGATGCCAGCCCCTTCTCAGTTCCGAAGAAACAGGATGAATCACCCATGATTGGGGATGGAGAAGATTATTTCCTTTC TTTGTTTGGTGATTCAAAGAAACTTACAGCACACTCAAACTACACTCAGAAAACTTTAAAATACTTTTCTATGATTCTTGAAGAAGTTGG CCAATTTACCTCCAGTTCTCTTGGAGATGTTGAAATAGCTGAAGTGAATGTCAAGGGTTTGTTCGTGAAGCTCATTAACTCTTCCCTTGA CAAAGAAATGGCAATTGGAGATCATATTCTCCAGCAAAATGTGAATGGACAAACCATTTCTTTGTACCGATTCCTTCCAAACATCGTAAT GCAGGCAAATTCCACAGTAACAGTGTGGGCAGCAGCATCTGAAGCAAAGCATCAACCTCCATCAGATTTTCTTTGGAAGGAACAAGACAA GTTTAGAGCAAGTCCTGATTGTATAACAATCCTGTGCAAACCGAACGGTCAAGCCATTGCGTGGTACACCCCTATCCACTGGAAGCAAGC GTGGGAAAAATTAGATGCTGACGTTGAATTTAACAGATGTTCAGTAGTATCTCCAACATTCCGAAAGCGTGTGTTTCAGTGGACAGCATC TACAGCTACAATAACTAAAGAAAAACAAGATCAACCTAAGAAAGATATCTCAAATTATCAGGTGGAACAAGCTCAAGTTCTTCTTAAGAG AGAGAAGGAAATCCCACCAACCGTTTTCCCTAATCGCAGCCCTTGGTGCCAGAATCCCTATGTCTCTGCACATCCTTACTGTCCTCTGAT TGAACCACACAATACATCCACCGCTGGAGGCAGATTGGATAGACAGCCCAGGACTCGGTCAACCAGACCTAATCGAGCCTCAGGGTCTAA GAAAAAGAAGACATCTGAGTCACAAAAGCAATAAGCAGTCAACTCAACCTTTAAAGTAATCTAGTCCACCCTCAACCAGCTACTAGAAAA GCAAAAGAGAACTCAAATCCCTGAGGCCTGCTCTGCAACCTCCCTGCTATTCCATGAGAGGGTGAAGACATCACATTTCTATATGGAAAA AGGATCCAAAATTTGTATTGCTGTAGAATTGGTGAATTATAGATGCTTGATGAAATCACAAGTCCTACCACTCCTGCCTTCCAAATCCCT GCAGAAAACAAGCAGATGGTTAGTATTATTCAATGGATAAAATTGCTATTTGCCTTAGATTTCTCTTTTTGTAAACAAAGTTATTTTGGG >85328_85328_4_SOX5-IFLTD1_SOX5_chr12_23793746_ENST00000545921_IFLTD1_chr12_25702480_ENST00000282881_length(amino acids)=371AA_BP=323 MSVMSSKRPASPYGEADGEVAMVTSRQKVEEEESDGLPAFHLPLHVSFPNKPHSEEFQPVSLLTQETCGHRTPTSQHNTMEVDGNKVMSS FAPHNSSTSPQKAEEGGRQSGESLSSTALGTPERRKGSLADVVDTLKQRKMEELIKNEPEETPSIEKLLSKDWKDKLLAMGSGNFGEIKG TPESLAEKERQLMGMINQLTSLREQLLAAHDEQKKLAASQIEKQRQQMELAKQQQEQIARQQQQLLQQQHKINLLQQQIQVQGQLPPLMI PVFPPDQRTLAAAAQQGFLLPPGFSYKAGCSDPYPVQLIPTTMAAAAAATPGLGPLQLQKRRQTWSIFFSTFFPKDVGFSCHNTAIVIFK -------------------------------------------------------------- >85328_85328_5_SOX5-IFLTD1_SOX5_chr12_23793746_ENST00000546136_IFLTD1_chr12_25702480_ENST00000282881_length(transcript)=2523nt_BP=981nt AGGATGTCTTCCAAGCGACCAGCCTCTCCGTATGGGGAAGCAGATGGAGAGGTAGCCATGGTGACAAGCAGACAGAAAGTGGAAGAAGAG GAGAGTGACGGGCTCCCAGCCTTTCACCTTCCCTTGCATGTGAGTTTTCCCAACAAGCCTCACTCTGAGGAATTTCAGCCAGTTTCTCTG CTGACGCAAGAGACTTGTGGCCATAGGACTCCCACTTCTCAGCACAATACAATGGAAGTTGATGGCAATAAAGTTATGTCTTCATTTGCC CCACACAACTCATCTACCTCACCTCAGAAGGCAGAAGAAGGTGGGCGACAGAGTGGCGAGTCCTTGTCTAGTACAGCCCTGGGAACTCCT GAACGGCGCAAGGGCAGTTTAGCTGATGTTGTTGACACCTTGAAGCAGAGGAAAATGGAAGAGCTCATCAAAAACGAGCCGGAAGAAACC CCCAGTATTGAAAAACTACTCTCAAAGGACTGGAAAGACAAGCTTCTTGCAATGGGATCGGGGAACTTTGGCGAAATAAAAGGGACTCCC GAGAGCTTAGCTGAGAAAGAAAGGCAACTCATGGGTATGATCAACCAGCTGACCAGCCTCCGAGAGCAGCTGTTGGCTGCCCACGATGAG CAGAAGAAACTAGCTGCCTCTCAGATTGAGAAACAGCGTCAGCAAATGGAGCTGGCCAAGCAGCAACAAGAACAAATTGCAAGACAGCAG CAGCAGCTTCTACAGCAACAACACAAAATCAATTTGCTCCAGCAACAGATCCAGGTTCAAGGTCAGCTGCCGCCATTAATGATTCCCGTA TTCCCTCCTGATCAACGGACACTGGCTGCAGCTGCCCAGCAAGGATTCCTCCTCCCTCCAGGCTTCAGCTATAAGGCTGGATGTAGTGAC CCTTACCCTGTTCAGCTGATCCCAACTACCATGGCAGCTGCTGCCGCAGCAACACCAGGCTTAGGCCCACTCCAACTGCAGAAGAGAAGA CAAACTTGGAGTATATTCTTTAGTACATTTTTCCCCAAAGATGTTGGGTTCAGTTGCCACAACACTGCCATTGTCATCTTCAAATTCCAG TGGAATGCCTCTTGGTTACTATCTGTCTAGTCCTCAGATTAGTAGAGTAACTATATCAACAACTGGACAATTGACTTCTAAAGCTACTGT AGGTAGCTGTTCCAGAGTGGAAAACAGCTTGGATGCCAGCCCCTTCTCAGTTCCGAAGAAACAGGATGAATCACCCATGATTGGGGATGG AGAAGATTATTTCCTTTCTTTGTTTGGTGATTCAAAGAAACTTACAGCACACTCAAACTACACTCAGAAAACTTTAAAATACTTTTCTAT GATTCTTGAAGAAGTTGGCCAATTTACCTCCAGTTCTCTTGGAGATGTTGAAATAGCTGAAGTGAATGTCAAGGGTTTGTTCGTGAAGCT CATTAACTCTTCCCTTGACAAAGAAATGGCAATTGGAGATCATATTCTCCAGCAAAATGTGAATGGACAAACCATTTCTTTGTACCGATT CCTTCCAAACATCGTAATGCAGGCAAATTCCACAGTAACAGTGTGGGCAGCAGCATCTGAAGCAAAGCATCAACCTCCATCAGATTTTCT TTGGAAGGAACAAGACAAGTTTAGAGCAAGTCCTGATTGTATAACAATCCTGTGCAAACCGAACGGTCAAGCCATTGCGTGGTACACCCC TATCCACTGGAAGCAAGCGTGGGAAAAATTAGATGCTGACGTTGAATTTAACAGATGTTCAGTAGTATCTCCAACATTCCGAAAGCGTGT GTTTCAGTGGACAGCATCTACAGCTACAATAACTAAAGAAAAACAAGATCAACCTAAGAAAGATATCTCAAATTATCAGGTGGAACAAGC TCAAGTTCTTCTTAAGAGAGAGAAGGAAATCCCACCAACCGTTTTCCCTAATCGCAGCCCTTGGTGCCAGAATCCCTATGTCTCTGCACA TCCTTACTGTCCTCTGATTGAACCACACAATACATCCACCGCTGGAGGCAGATTGGATAGACAGCCCAGGACTCGGTCAACCAGACCTAA TCGAGCCTCAGGGTCTAAGAAAAAGAAGACATCTGAGTCACAAAAGCAATAAGCAGTCAACTCAACCTTTAAAGTAATCTAGTCCACCCT CAACCAGCTACTAGAAAAGCAAAAGAGAACTCAAATCCCTGAGGCCTGCTCTGCAACCTCCCTGCTATTCCATGAGAGGGTGAAGACATC ACATTTCTATATGGAAAAAGGATCCAAAATTTGTATTGCTGTAGAATTGGTGAATTATAGATGCTTGATGAAATCACAAGTCCTACCACT CCTGCCTTCCAAATCCCTGCAGAAAACAAGCAGATGGTTAGTATTATTCAATGGATAAAATTGCTATTTGCCTTAGATTTCTCTTTTTGT AAACAAAGTTATTTTGGGTACAGAACTCACAAAAGAAGAGCACGTGCAATTGTTTAACCATTTTACATTGACTGATAAATCTCTTTTTTC >85328_85328_5_SOX5-IFLTD1_SOX5_chr12_23793746_ENST00000546136_IFLTD1_chr12_25702480_ENST00000282881_length(amino acids)=368AA_BP=320 MSSKRPASPYGEADGEVAMVTSRQKVEEEESDGLPAFHLPLHVSFPNKPHSEEFQPVSLLTQETCGHRTPTSQHNTMEVDGNKVMSSFAP HNSSTSPQKAEEGGRQSGESLSSTALGTPERRKGSLADVVDTLKQRKMEELIKNEPEETPSIEKLLSKDWKDKLLAMGSGNFGEIKGTPE SLAEKERQLMGMINQLTSLREQLLAAHDEQKKLAASQIEKQRQQMELAKQQQEQIARQQQQLLQQQHKINLLQQQIQVQGQLPPLMIPVF PPDQRTLAAAAQQGFLLPPGFSYKAGCSDPYPVQLIPTTMAAAAAATPGLGPLQLQKRRQTWSIFFSTFFPKDVGFSCHNTAIVIFKFQW -------------------------------------------------------------- |
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Fusion Gene PPI Analysis for SOX5-IFLTD1 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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Related Drugs for SOX5-IFLTD1 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.8 2021-05-08) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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Related Diseases for SOX5-IFLTD1 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
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