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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:SPAG16-CUL3 (FusionGDB2 ID:85419)

Fusion Gene Summary for SPAG16-CUL3

check button Fusion gene summary
Fusion gene informationFusion gene name: SPAG16-CUL3
Fusion gene ID: 85419
HgeneTgene
Gene symbol

SPAG16

CUL3

Gene ID

79582

8452

Gene namesperm associated antigen 16cullin 3
SynonymsPF20|WDR29CUL-3|PHA2E
Cytomap

2q34

2q36.2

Type of geneprotein-codingprotein-coding
Descriptionsperm-associated antigen 16 proteinWD repeat domain 29pf20 protein homologsperm-associated WD repeat proteincullin-3
Modification date2020031320200327
UniProtAcc.

Q13618

Ensembl transtripts involved in fusion geneENST00000414961, ENST00000272898, 
ENST00000331683, ENST00000374309, 
ENST00000413312, ENST00000432529, 
ENST00000447990, 		ENST00000264414, 
ENST00000344951, ENST00000409096, 
ENST00000409777, ENST00000432260, 
Fusion gene scores* DoF score6 X 5 X 4=1208 X 8 X 5=320
# samples 69
** MAII scorelog2(6/120*10)=-1
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(9/320*10)=-1.83007499855769
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: SPAG16 [Title/Abstract] AND CUL3 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointCUL3(225360549)-SPAG16(214174783), # samples:3
SPAG16(214162081)-CUL3(225346795), # samples:3
Anticipated loss of major functional domain due to fusion event.CUL3-SPAG16 seems lost the major protein functional domain in Hgene partner, which is a CGC due to the frame-shifted ORF.
CUL3-SPAG16 seems lost the major protein functional domain in Hgene partner, which is a epigenetic factor due to the frame-shifted ORF.
SPAG16-CUL3 seems lost the major protein functional domain in Tgene partner, which is a CGC due to the frame-shifted ORF.
SPAG16-CUL3 seems lost the major protein functional domain in Tgene partner, which is a epigenetic factor due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
TgeneCUL3

GO:0000209

protein polyubiquitination

19261606

TgeneCUL3

GO:0006511

ubiquitin-dependent protein catabolic process

25401743|27561354

TgeneCUL3

GO:0006513

protein monoubiquitination

22358839

TgeneCUL3

GO:0006888

ER to Golgi vesicle-mediated transport

22358839

TgeneCUL3

GO:0016567

protein ubiquitination

17543862|19782033|19995937|20389280|23213400

TgeneCUL3

GO:0031145

anaphase-promoting complex-dependent catabolic process

10500095

TgeneCUL3

GO:0043161

proteasome-mediated ubiquitin-dependent protein catabolic process

19261606|19782033|20389280

TgeneCUL3

GO:0071630

nuclear protein quality control by the ubiquitin-proteasome system

27561354


check buttonFusion gene breakpoints across SPAG16 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across CUL3 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4LUSCTCGA-O2-A52V-01ASPAG16chr2

214162081

-CUL3chr2

225346795

-
ChimerDB4LUSCTCGA-O2-A52V-01ASPAG16chr2

214162081

+CUL3chr2

225346795

-
ChimerDB4LUSCTCGA-O2-A52VSPAG16chr2

214162081

+CUL3chr2

225346795

-


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Fusion Gene ORF analysis for SPAG16-CUL3

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
3UTR-3CDSENST00000414961ENST00000264414SPAG16chr2

214162081

+CUL3chr2

225346795

-
3UTR-3CDSENST00000414961ENST00000344951SPAG16chr2

214162081

+CUL3chr2

225346795

-
3UTR-3CDSENST00000414961ENST00000409096SPAG16chr2

214162081

+CUL3chr2

225346795

-
3UTR-3CDSENST00000414961ENST00000409777SPAG16chr2

214162081

+CUL3chr2

225346795

-
3UTR-intronENST00000414961ENST00000432260SPAG16chr2

214162081

+CUL3chr2

225346795

-
5CDS-intronENST00000272898ENST00000432260SPAG16chr2

214162081

+CUL3chr2

225346795

-
5CDS-intronENST00000331683ENST00000432260SPAG16chr2

214162081

+CUL3chr2

225346795

-
5CDS-intronENST00000374309ENST00000432260SPAG16chr2

214162081

+CUL3chr2

225346795

-
5CDS-intronENST00000413312ENST00000432260SPAG16chr2

214162081

+CUL3chr2

225346795

-
5CDS-intronENST00000432529ENST00000432260SPAG16chr2

214162081

+CUL3chr2

225346795

-
5CDS-intronENST00000447990ENST00000432260SPAG16chr2

214162081

+CUL3chr2

225346795

-
Frame-shiftENST00000374309ENST00000264414SPAG16chr2

214162081

+CUL3chr2

225346795

-
Frame-shiftENST00000374309ENST00000344951SPAG16chr2

214162081

+CUL3chr2

225346795

-
Frame-shiftENST00000374309ENST00000409096SPAG16chr2

214162081

+CUL3chr2

225346795

-
Frame-shiftENST00000374309ENST00000409777SPAG16chr2

214162081

+CUL3chr2

225346795

-
In-frameENST00000272898ENST00000264414SPAG16chr2

214162081

+CUL3chr2

225346795

-
In-frameENST00000272898ENST00000344951SPAG16chr2

214162081

+CUL3chr2

225346795

-
In-frameENST00000272898ENST00000409096SPAG16chr2

214162081

+CUL3chr2

225346795

-
In-frameENST00000272898ENST00000409777SPAG16chr2

214162081

+CUL3chr2

225346795

-
In-frameENST00000331683ENST00000264414SPAG16chr2

214162081

+CUL3chr2

225346795

-
In-frameENST00000331683ENST00000344951SPAG16chr2

214162081

+CUL3chr2

225346795

-
In-frameENST00000331683ENST00000409096SPAG16chr2

214162081

+CUL3chr2

225346795

-
In-frameENST00000331683ENST00000409777SPAG16chr2

214162081

+CUL3chr2

225346795

-
In-frameENST00000413312ENST00000264414SPAG16chr2

214162081

+CUL3chr2

225346795

-
In-frameENST00000413312ENST00000344951SPAG16chr2

214162081

+CUL3chr2

225346795

-
In-frameENST00000413312ENST00000409096SPAG16chr2

214162081

+CUL3chr2

225346795

-
In-frameENST00000413312ENST00000409777SPAG16chr2

214162081

+CUL3chr2

225346795

-
In-frameENST00000432529ENST00000264414SPAG16chr2

214162081

+CUL3chr2

225346795

-
In-frameENST00000432529ENST00000344951SPAG16chr2

214162081

+CUL3chr2

225346795

-
In-frameENST00000432529ENST00000409096SPAG16chr2

214162081

+CUL3chr2

225346795

-
In-frameENST00000432529ENST00000409777SPAG16chr2

214162081

+CUL3chr2

225346795

-
In-frameENST00000447990ENST00000264414SPAG16chr2

214162081

+CUL3chr2

225346795

-
In-frameENST00000447990ENST00000344951SPAG16chr2

214162081

+CUL3chr2

225346795

-
In-frameENST00000447990ENST00000409096SPAG16chr2

214162081

+CUL3chr2

225346795

-
In-frameENST00000447990ENST00000409777SPAG16chr2

214162081

+CUL3chr2

225346795

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000331683SPAG16chr2214162081+ENST00000264414CUL3chr2225346795-493437456838260
ENST00000331683SPAG16chr2214162081+ENST00000344951CUL3chr2225346795-493237456838260
ENST00000331683SPAG16chr2214162081+ENST00000409096CUL3chr2225346795-116237456838260
ENST00000331683SPAG16chr2214162081+ENST00000409777CUL3chr2225346795-114537456838260
ENST00000432529SPAG16chr2214162081+ENST00000264414CUL3chr2225346795-493137153835260
ENST00000432529SPAG16chr2214162081+ENST00000344951CUL3chr2225346795-492937153835260
ENST00000432529SPAG16chr2214162081+ENST00000409096CUL3chr2225346795-115937153835260
ENST00000432529SPAG16chr2214162081+ENST00000409777CUL3chr2225346795-114237153835260
ENST00000413312SPAG16chr2214162081+ENST00000264414CUL3chr2225346795-4992432180896238
ENST00000413312SPAG16chr2214162081+ENST00000344951CUL3chr2225346795-4990432180896238
ENST00000413312SPAG16chr2214162081+ENST00000409096CUL3chr2225346795-1220432180896238
ENST00000413312SPAG16chr2214162081+ENST00000409777CUL3chr2225346795-1203432180896238
ENST00000272898SPAG16chr2214162081+ENST00000264414CUL3chr2225346795-48432834747247
ENST00000272898SPAG16chr2214162081+ENST00000344951CUL3chr2225346795-48412834747247
ENST00000272898SPAG16chr2214162081+ENST00000409096CUL3chr2225346795-10712834747247
ENST00000272898SPAG16chr2214162081+ENST00000409777CUL3chr2225346795-10542834747247
ENST00000447990SPAG16chr2214162081+ENST00000264414CUL3chr2225346795-48422823746247
ENST00000447990SPAG16chr2214162081+ENST00000344951CUL3chr2225346795-48402823746247
ENST00000447990SPAG16chr2214162081+ENST00000409096CUL3chr2225346795-10702823746247
ENST00000447990SPAG16chr2214162081+ENST00000409777CUL3chr2225346795-10532823746247

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000331683ENST00000264414SPAG16chr2214162081+CUL3chr2225346795-0.0001872030.9998128
ENST00000331683ENST00000344951SPAG16chr2214162081+CUL3chr2225346795-0.0001861970.99981385
ENST00000331683ENST00000409096SPAG16chr2214162081+CUL3chr2225346795-0.0009728940.99902713
ENST00000331683ENST00000409777SPAG16chr2214162081+CUL3chr2225346795-0.0009044450.99909556
ENST00000432529ENST00000264414SPAG16chr2214162081+CUL3chr2225346795-0.0001877190.9998123
ENST00000432529ENST00000344951SPAG16chr2214162081+CUL3chr2225346795-0.0001866740.9998134
ENST00000432529ENST00000409096SPAG16chr2214162081+CUL3chr2225346795-0.0009241290.9990759
ENST00000432529ENST00000409777SPAG16chr2214162081+CUL3chr2225346795-0.000865070.99913496
ENST00000413312ENST00000264414SPAG16chr2214162081+CUL3chr2225346795-0.0003376670.9996623
ENST00000413312ENST00000344951SPAG16chr2214162081+CUL3chr2225346795-0.0003359550.99966407
ENST00000413312ENST00000409096SPAG16chr2214162081+CUL3chr2225346795-0.0014953130.99850476
ENST00000413312ENST00000409777SPAG16chr2214162081+CUL3chr2225346795-0.0014312620.99856865
ENST00000272898ENST00000264414SPAG16chr2214162081+CUL3chr2225346795-0.0001877660.9998123
ENST00000272898ENST00000344951SPAG16chr2214162081+CUL3chr2225346795-0.000186630.9998134
ENST00000272898ENST00000409096SPAG16chr2214162081+CUL3chr2225346795-0.0010463760.9989536
ENST00000272898ENST00000409777SPAG16chr2214162081+CUL3chr2225346795-0.0009817630.9990182
ENST00000447990ENST00000264414SPAG16chr2214162081+CUL3chr2225346795-0.0001865720.9998135
ENST00000447990ENST00000344951SPAG16chr2214162081+CUL3chr2225346795-0.0001854420.99981457
ENST00000447990ENST00000409096SPAG16chr2214162081+CUL3chr2225346795-0.001070110.9989299
ENST00000447990ENST00000409777SPAG16chr2214162081+CUL3chr2225346795-0.0010015170.99899846

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Fusion Genomic Features for SPAG16-CUL3


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for SPAG16-CUL3


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr2:225360549/chr2:214174783)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
.CUL3

Q13618

FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Core component of multiple cullin-RING-based BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complexes which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. BCR complexes and ARIH1 collaborate in tandem to mediate ubiquitination of target proteins (PubMed:27565346). As a scaffold protein may contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme. The E3 ubiquitin-protein ligase activity of the complex is dependent on the neddylation of the cullin subunit and is inhibited by the association of the deneddylated cullin subunit with TIP120A/CAND1. The functional specificity of the BCR complex depends on the BTB domain-containing protein as the substrate recognition component. BCR(KLHL42) is involved in ubiquitination of KATNA1. BCR(SPOP) is involved in ubiquitination of BMI1/PCGF4, BRMS1, MACROH2A1 and DAXX, GLI2 and GLI3. Can also form a cullin-RING-based BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex containing homodimeric SPOPL or the heterodimer formed by SPOP and SPOPL; these complexes have lower ubiquitin ligase activity. BCR(KLHL9-KLHL13) controls the dynamic behavior of AURKB on mitotic chromosomes and thereby coordinates faithful mitotic progression and completion of cytokinesis. BCR(KLHL12) is involved in ER-Golgi transport by regulating the size of COPII coats, thereby playing a key role in collagen export, which is required for embryonic stem (ES) cells division: BCR(KLHL12) acts by mediating monoubiquitination of SEC31 (SEC31A or SEC31B) (PubMed:22358839, PubMed:27716508). BCR(KLHL3) acts as a regulator of ion transport in the distal nephron; by mediating ubiquitination of WNK4 (PubMed:23387299, PubMed:23453970, PubMed:23576762). The BCR(KLHL20) E3 ubiquitin ligase complex is involved in interferon response and anterograde Golgi to endosome transport: it mediates both ubiquitination leading to degradation and 'Lys-33'-linked ubiquitination (PubMed:20389280, PubMed:21840486, PubMed:21670212, PubMed:24768539). The BCR(KLHL21) E3 ubiquitin ligase complex regulates localization of the chromosomal passenger complex (CPC) from chromosomes to the spindle midzone in anaphase and mediates the ubiquitination of AURKB (PubMed:19995937). The BCR(KLHL22) ubiquitin ligase complex mediates monoubiquitination of PLK1, leading to PLK1 dissociation from phosphoreceptor proteins and subsequent removal from kinetochores, allowing silencing of the spindle assembly checkpoint (SAC) and chromosome segregation (PubMed:23455478). The BCR(KLHL22) ubiquitin ligase complex is also responsible for the amino acid-stimulated 'Lys-48' polyubiquitination and proteasomal degradation of DEPDC5. Through the degradation of DEPDC5, releases the GATOR1 complex-mediated inhibition of the TORC1 pathway (PubMed:29769719). The BCR(KLHL25) ubiquitin ligase complex is involved in translational homeostasis by mediating ubiquitination and subsequent degradation of hypophosphorylated EIF4EBP1 (4E-BP1) (PubMed:22578813). The BCR(KBTBD8) complex acts by mediating monoubiquitination of NOLC1 and TCOF1, leading to remodel the translational program of differentiating cells in favor of neural crest specification (PubMed:26399832). Involved in ubiquitination of cyclin E and of cyclin D1 (in vitro) thus involved in regulation of G1/S transition. Involved in the ubiquitination of KEAP1, ENC1 and KLHL41 (PubMed:15983046). In concert with ATF2 and RBX1, promotes degradation of KAT5 thereby attenuating its ability to acetylate and activate ATM. The BCR(KCTD17) E3 ubiquitin ligase complex mediates ubiquitination and degradation of TCHP, a down-regulator of cilium assembly, thereby inducing ciliogenesis (PubMed:25270598). The BCR(KLHL24) E3 ubiquitin ligase complex mediates ubiquitination of KRT14, controls KRT14 levels during keratinocytes differentiation, and is essential for skin integrity (PubMed:27798626). The BCR(KLHL18) E3 ubiquitin ligase complex mediates the ubiquitination of AURKA leading to its activation at the centrosome which is required for initiating mitotic entry (PubMed:23213400). The BCR(KEAP1) E3 ubiquitin ligase complex acts as a key sensor of oxidative and electrophilic stress by mediating ubiquitination and degradation of NFE2L2/NRF2, a transcription factor regulating expression of many cytoprotective genes (PubMed:15601839, PubMed:16006525). {ECO:0000269|PubMed:10500095, ECO:0000269|PubMed:11311237, ECO:0000269|PubMed:15601839, ECO:0000269|PubMed:15897469, ECO:0000269|PubMed:15983046, ECO:0000269|PubMed:16006525, ECO:0000269|PubMed:16524876, ECO:0000269|PubMed:17543862, ECO:0000269|PubMed:18397884, ECO:0000269|PubMed:19261606, ECO:0000269|PubMed:19995937, ECO:0000269|PubMed:20389280, ECO:0000269|PubMed:21670212, ECO:0000269|PubMed:21840486, ECO:0000269|PubMed:22085717, ECO:0000269|PubMed:22358839, ECO:0000269|PubMed:22578813, ECO:0000269|PubMed:22632832, ECO:0000269|PubMed:23213400, ECO:0000269|PubMed:23387299, ECO:0000269|PubMed:23453970, ECO:0000269|PubMed:23455478, ECO:0000269|PubMed:23576762, ECO:0000269|PubMed:24768539, ECO:0000269|PubMed:25270598, ECO:0000269|PubMed:26399832, ECO:0000269|PubMed:27565346, ECO:0000269|PubMed:27716508, ECO:0000269|PubMed:27798626, ECO:0000269|PubMed:29769719}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneSPAG16chr2:214162081chr2:225346795ENST00000272898+310152_26793348.0Coiled coilOntology_term=ECO:0000255
HgeneSPAG16chr2:214162081chr2:225346795ENST00000331683+316152_26793632.0Coiled coilOntology_term=ECO:0000255
HgeneSPAG16chr2:214162081chr2:225346795ENST00000413312+27152_26762252.0Coiled coilOntology_term=ECO:0000255
HgeneSPAG16chr2:214162081chr2:225346795ENST00000432529+35152_26793184.0Coiled coilOntology_term=ECO:0000255
HgeneSPAG16chr2:214162081chr2:225346795ENST00000272898+310350_38993348.0RepeatNote=WD 1
HgeneSPAG16chr2:214162081chr2:225346795ENST00000272898+310392_43193348.0RepeatNote=WD 2
HgeneSPAG16chr2:214162081chr2:225346795ENST00000272898+310434_47393348.0RepeatNote=WD 3
HgeneSPAG16chr2:214162081chr2:225346795ENST00000272898+310476_51593348.0RepeatNote=WD 4
HgeneSPAG16chr2:214162081chr2:225346795ENST00000272898+310518_55793348.0RepeatNote=WD 5
HgeneSPAG16chr2:214162081chr2:225346795ENST00000272898+310560_60093348.0RepeatNote=WD 6
HgeneSPAG16chr2:214162081chr2:225346795ENST00000272898+310601_63093348.0RepeatNote=WD 7
HgeneSPAG16chr2:214162081chr2:225346795ENST00000331683+316350_38993632.0RepeatNote=WD 1
HgeneSPAG16chr2:214162081chr2:225346795ENST00000331683+316392_43193632.0RepeatNote=WD 2
HgeneSPAG16chr2:214162081chr2:225346795ENST00000331683+316434_47393632.0RepeatNote=WD 3
HgeneSPAG16chr2:214162081chr2:225346795ENST00000331683+316476_51593632.0RepeatNote=WD 4
HgeneSPAG16chr2:214162081chr2:225346795ENST00000331683+316518_55793632.0RepeatNote=WD 5
HgeneSPAG16chr2:214162081chr2:225346795ENST00000331683+316560_60093632.0RepeatNote=WD 6
HgeneSPAG16chr2:214162081chr2:225346795ENST00000331683+316601_63093632.0RepeatNote=WD 7
HgeneSPAG16chr2:214162081chr2:225346795ENST00000413312+27350_38962252.0RepeatNote=WD 1
HgeneSPAG16chr2:214162081chr2:225346795ENST00000413312+27392_43162252.0RepeatNote=WD 2
HgeneSPAG16chr2:214162081chr2:225346795ENST00000413312+27434_47362252.0RepeatNote=WD 3
HgeneSPAG16chr2:214162081chr2:225346795ENST00000413312+27476_51562252.0RepeatNote=WD 4
HgeneSPAG16chr2:214162081chr2:225346795ENST00000413312+27518_55762252.0RepeatNote=WD 5
HgeneSPAG16chr2:214162081chr2:225346795ENST00000413312+27560_60062252.0RepeatNote=WD 6
HgeneSPAG16chr2:214162081chr2:225346795ENST00000413312+27601_63062252.0RepeatNote=WD 7
HgeneSPAG16chr2:214162081chr2:225346795ENST00000432529+35350_38993184.0RepeatNote=WD 1
HgeneSPAG16chr2:214162081chr2:225346795ENST00000432529+35392_43193184.0RepeatNote=WD 2
HgeneSPAG16chr2:214162081chr2:225346795ENST00000432529+35434_47393184.0RepeatNote=WD 3
HgeneSPAG16chr2:214162081chr2:225346795ENST00000432529+35476_51593184.0RepeatNote=WD 4
HgeneSPAG16chr2:214162081chr2:225346795ENST00000432529+35518_55793184.0RepeatNote=WD 5
HgeneSPAG16chr2:214162081chr2:225346795ENST00000432529+35560_60093184.0RepeatNote=WD 6
HgeneSPAG16chr2:214162081chr2:225346795ENST00000432529+35601_63093184.0RepeatNote=WD 7


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Fusion Gene Sequence for SPAG16-CUL3


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>85419_85419_1_SPAG16-CUL3_SPAG16_chr2_214162081_ENST00000272898_CUL3_chr2_225346795_ENST00000264414_length(transcript)=4843nt_BP=283nt
AGAGATGGCTGCTCAGCGAGGGATGCCCAGCTCCGCCGTGAGGGTCCTGGAAGAGGCGTTGGGCATGGGTTTGACGGCAGCCGGGGACGC
GAGGGACACGGCGGACGCGGTGGCGGCTGAGGGCGCCTACTACCTGGAACAGGTCACCATAACTGAAGCATCTGAAGATGACTATGAATA
TGAAGAGATACCAGATGACAATTTTAGCATCCCAGAAGGTGAAGAAGATCTGGCAAAAGCAATTCAGATGGCCCAAGAACAGGCTACAGA
TACTGAAATTTTGGAAATTCAGCAAGAGACAGATATCCCTGAAAGAGAGCTTGTTAGAGCCCTACAGTCCCTCGCCTGTGGTAAACCAAC
ACAGCGGGTTCTTACAAAAGAACCCAAATCAAAGGAAATAGAAAATGGTCATATATTTACAGTTAATGATCAATTCACATCCAAACTACA
CAGAGTCAAGATTCAAACAGTTGCTGCCAAACAAGGTGAATCCGACCCAGAGAGGAAAGAAACAAGGCAGAAAGTAGACGACGACAGAAA
ACATGAGATAGAAGCTGCTATAGTGCGGATAATGAAATCTAGAAAGAAGATGCAGCACAATGTTCTAGTAGCGGAGGTAACTCAGCAGTT
GAAGGCGCGATTCTTACCAAGTCCAGTTGTTATTAAGAAACGTATTGAAGGACTTATTGAGAGAGAATATTTGGCACGAACACCTGAGGA
TCGCAAAGTATACACATATGTAGCATAAAATGCGTTCAGAAATTTGATTTATTCTTGGACTGTACTCTTCGCATGGACTGGGAAGTTCTT
TTAAATCATTAAATATTAAGACGACCATCTCTTCTATTAAATTACAGTACATGTTCTAGACCATTGAGATCAAGCCTTTACTCCCTTTGA
GAGTTTCCAACATCAGTTGATTGAGCTTCAGGCTTTACAACGTTTATCCCTGTAGAGATCATCTTTACAGTTCCTCGGGAAAATGTGAAT
GTGCTGCGTTTTGTTTTCTTTACTGTATGAAAACAGGAAAATAAAAGAGAAATTTAGAAAATACAGCTCATTACAATAAAATTGTTGGAT
TTCATTTCCCCAGGTCTTCAGTGTTGATGTAAATGTGTTTTGTAGTGTTGCTTAGCACTTTGCGCATTGTGTAAGTTGGGTAACAAAAAT
GGCAAAAGAAATGCAGATTTCCCAGTTATCTTGCTCTGAAGACATTTCTTTAGCTAGTCTTATTTAATTTTAAAGGTTTGATAAATATAC
AAAGACCCAAGCATACAATTTGAGCATGCTGTATTCTACCACTTGCACTTACTCATCTTCTAGCCTTATGACCAGGAACCTTTGTTTTGG
GCTCAAGTACACATCCTGATTTGGTTTCTCCCTGTTGTAATTTGAGATTTCCCAAATTAAGTCTTATAATGATTAGGTTTTGTTCTGAGT
TATTTCTAGAGAAAGAAAGTATTTTAGTATGTGTAAATTGTACAATAATTTTTTTGCTGTTGTACTCACTGCTAATAGTGGATTGTATAG
GGTGGTGTTTTTATTTCATTTATTGTAGACAAAAATAATGAATTTAGTATACACATACCCACTAATTCAAGTATGTCAGAGCACAAAGTT
GGCAGCTGGTTATATTTAATTCAGCCCCTCTGAAAAGCACATACAGTCTATACTTTGTTTATAAATACCCTAGGTCCTCCCTGCCCCTAA
ATATATATTTTGGTGAAGCTGTGGTGCACTATTAATTTTCTGTTTCAAAATGCAATCTAAAGATGCAATAAATATGATGACCTTGATAGT
TTTAATGAAATCTTCAATTCTTGCAGCTGTGTTTTGGAAAGTGATTAAGCAATATTTCTCAAACCTGATGATTCTTGGATATTTAGCTAT
TGTCCTCCAAAGAGTCATCGTTTCACGTTTTCAAACATGTGCTTTGTGCTGAAGATTCTTGTCAGATATCCTGTGCTTCCAGAGTATTTT
TATCTTCAATTTTATTTAATTTTGTTTCATTTTGTTTTCATAAGACAATGTTTCAGATATGTAATGGGGCAAACCACTATAGATTTCTGT
TGGATAGAAAAATGAAATGTTACTAATAAGTTTAAATTGACCCTTCGTTGACTATCAGTACTGTTGATACATTTATTAGAATGTATGTCT
CAGAAGATGGTTTCTGTTTAAATTTATGGTCAAGTTACAACAACTGAATTCTAATATGGATTAAAAACTCCACATAAATATTTTTCCCCA
TGCGTCTTGGGTTATAATTTTCCTTTTAGACTTGCAAATATGCTTTTATTGCAATTTTGTCTCCATCTGTACTGTAGAATTACAAGCCTT
GTGCTCTTTATCTCTACATTTTCCACTTCTACATGATGCAATTAAGATGCCAATGAAAAGTATTGTGAACATTATTCTCAGGACACTTTT
ACCATACTTGAGTAGTACTAAGTCAGGTGTAACATGGAAAGCTAAGGGTTTCACCTTCTGATTTTGACATAATTGGAAATTTTCTATAAT
GGTAAGATGTTTATAGGAAAGTAATGGTAGTTCATGTTTGAGAATTTTTTTATTGCTTTCATTTCCCAGTTAAATGATATTTAACACCTG
GGAAAACAGGACAGCTCAGATTGTCGAGTTAGTAAACATGAGCGATGTAAAAACTTTATTTGAAATCTCCTAAGTGAGACATTAAACATT
TTAGTGCTAGTTTAAGCCATTAAAAGTAAAGTTTAAGTTTACGTCATTGTCTCAAGTGTGGCTGTAAAAATCAGATCTAGAGTTTAGAGA
CATACTTGTTAACTTTGGAGCACAGGTTTGATATTTATGCTTCTAAATACATTAAAACATTTCTGAATTGCAGTTGAATGGTTGGAGATT
GCTGGCGATGTGATGCTGCACTGAAAAAACTGGTCACACAAAATGTTTATATGTTTGACTGCATAAGTATTATTTTAGGTCATAAAGGTT
ATAACAAAATACATTTAACATTGCTTTCTTTTTAGCAAGAGGTCACAGATGCTATTTTTTCTCAGTTTTTAATGCTTTAATTTGAAAGAA
AAATGCATCCTAACCATTCCATCCTGTTGGTGCAGAGAAATTTTGGTGATTTATTAGAAGACTTTTAAGGAGGGTGGATACATAGTTTTT
CAACTGCAAAAATCATGTCATCTCTTCAGTAACTGTTAAAGTGTAATTCTCTGCCTTCATTATCAAGTCCAGGACAGTGTTTATTTTGAA
TCGTTAACATTATTTAAAGACTGAAAATTCATTGCAATTAGGGAACGCACAGCCTCACAAAAAGTGGTTGTGATTGCAAGGATTCTTTAT
GTCAGTGAACTTAAAAAGGGAATGGGGGAAGAGATGCATGCCTTTCTAAAGGTATGCTAGAGTCACCTGTGTAGCATTGTAATTATGTAC
TATCAAACCCCCAAGATGCTGATGATAGGCCTTCTCTGTAAGAATCCTTCTCATAGTGAAGCACTGTTGATGTTTTGTTCACCGGATATG
TTGGGTAGCAGAAAAGGCCTAGAACCAGTTTTAAGATTATGCCTACATCTCTAGAAGACTAGTACACTGGCATCATCTTAGGTTTCTAAA
TATTATTTAATTCCTTAATTTGGAAAGCAGTTTTAATGTTTACAGTTTAAGATACTCATTTTCAGTAACTAGTGTTAAAGATTTTTATCT
TTGCCTGTCTACTGTAACTTAAGACTTTCATAGAATAATTTTTTATAGAGTATATGGTATATTGTGTCAATCTTGGAAGGAAAGCTGTTG
CATATCAATTGTAGGTCATGTATTTTACTATATGTTGCATAGTATTTTGCATTCTGTAAATACGAATGTTAAAACATTTCAGGTCAGCAA
AATTAGAAGTCATTTCTAGTCCTCAAAGCAGAAATAATTAGAAATGTTAACATTTAAGTGCTTATCATATGCCAGATACTATTCTGAATA
TTTTATGTATATTCATTCATTTAGTTGTCATATTGGCTTTATGTGACATAACTGTCATTATACCAGTGTTGTCCAAGGTTGCTAGCAGGA
AATGGCAGAGCCAGGAGTTGGACCTAGGTTTAATCCTATCCATATTCCATGTTACAAATTGACATGATTTTCCATATTAAAAAATTTTCA
TTTATTTTGTACCTCATTCACATGAATAGTAATGTGACAAACTAAAGTTAATACATGAAGCATTGCAATATGGAATTTTGCACATTTTTG
TTAGCTTTACATTATTTGCTGATACCAACTTTTGGTAGGAAGGAAAACAGGGAAGGTGATTGCTGCTATTCTGGAATGTGTCCATTGAAA
AGAAAATAGGCGCTTTGTCTCCTACAATCTTAGAGAAAGTTTTACATACTTAAGTGGGTACCACAGATAGGCATGTACCTTAAATTCAAA
TCTACAGTTTTACAAAATGTTTTCCTTTGTGTGCCTTTCCTATGTCAAATTAGCCAGAAGGAAGAAGAGACGTTAAGAATGGCAGATAAA
TTTAACAGGTAATGATACAGAGATTGGCCATTACGCCAGCTCTCAGGAGAAAAACAACTAGGATGTCTTGAAACCCGTGCATTTAATTTT
AGAAATGGCAAATTTGTAAGCGTGTCATTTAAGTAATTTGATGCTCAGTTTTAGGGTCTAAGTTGACCTCGAGTGAGCCATGCAAAAATA
GCTTTAAAATTATACATGAGCAGCTCAAAGTAAACGTGTATTTTTTAGTAACAATGAAATTGTCAAATTTCAAGATTTTAATAACAGGAC

>85419_85419_1_SPAG16-CUL3_SPAG16_chr2_214162081_ENST00000272898_CUL3_chr2_225346795_ENST00000264414_length(amino acids)=247AA_BP=93
MAAQRGMPSSAVRVLEEALGMGLTAAGDARDTADAVAAEGAYYLEQVTITEASEDDYEYEEIPDDNFSIPEGEEDLAKAIQMAQEQATDT
EILEIQQETDIPERELVRALQSLACGKPTQRVLTKEPKSKEIENGHIFTVNDQFTSKLHRVKIQTVAAKQGESDPERKETRQKVDDDRKH

--------------------------------------------------------------
>85419_85419_2_SPAG16-CUL3_SPAG16_chr2_214162081_ENST00000272898_CUL3_chr2_225346795_ENST00000344951_length(transcript)=4841nt_BP=283nt
AGAGATGGCTGCTCAGCGAGGGATGCCCAGCTCCGCCGTGAGGGTCCTGGAAGAGGCGTTGGGCATGGGTTTGACGGCAGCCGGGGACGC
GAGGGACACGGCGGACGCGGTGGCGGCTGAGGGCGCCTACTACCTGGAACAGGTCACCATAACTGAAGCATCTGAAGATGACTATGAATA
TGAAGAGATACCAGATGACAATTTTAGCATCCCAGAAGGTGAAGAAGATCTGGCAAAAGCAATTCAGATGGCCCAAGAACAGGCTACAGA
TACTGAAATTTTGGAAATTCAGCAAGAGACAGATATCCCTGAAAGAGAGCTTGTTAGAGCCCTACAGTCCCTCGCCTGTGGTAAACCAAC
ACAGCGGGTTCTTACAAAAGAACCCAAATCAAAGGAAATAGAAAATGGTCATATATTTACAGTTAATGATCAATTCACATCCAAACTACA
CAGAGTCAAGATTCAAACAGTTGCTGCCAAACAAGGTGAATCCGACCCAGAGAGGAAAGAAACAAGGCAGAAAGTAGACGACGACAGAAA
ACATGAGATAGAAGCTGCTATAGTGCGGATAATGAAATCTAGAAAGAAGATGCAGCACAATGTTCTAGTAGCGGAGGTAACTCAGCAGTT
GAAGGCGCGATTCTTACCAAGTCCAGTTGTTATTAAGAAACGTATTGAAGGACTTATTGAGAGAGAATATTTGGCACGAACACCTGAGGA
TCGCAAAGTATACACATATGTAGCATAAAATGCGTTCAGAAATTTGATTTATTCTTGGACTGTACTCTTCGCATGGACTGGGAAGTTCTT
TTAAATCATTAAATATTAAGACGACCATCTCTTCTATTAAATTACAGTACATGTTCTAGACCATTGAGATCAAGCCTTTACTCCCTTTGA
GAGTTTCCAACATCAGTTGATTGAGCTTCAGGCTTTACAACGTTTATCCCTGTAGAGATCATCTTTACAGTTCCTCGGGAAAATGTGAAT
GTGCTGCGTTTTGTTTTCTTTACTGTATGAAAACAGGAAAATAAAAGAGAAATTTAGAAAATACAGCTCATTACAATAAAATTGTTGGAT
TTCATTTCCCCAGGTCTTCAGTGTTGATGTAAATGTGTTTTGTAGTGTTGCTTAGCACTTTGCGCATTGTGTAAGTTGGGTAACAAAAAT
GGCAAAAGAAATGCAGATTTCCCAGTTATCTTGCTCTGAAGACATTTCTTTAGCTAGTCTTATTTAATTTTAAAGGTTTGATAAATATAC
AAAGACCCAAGCATACAATTTGAGCATGCTGTATTCTACCACTTGCACTTACTCATCTTCTAGCCTTATGACCAGGAACCTTTGTTTTGG
GCTCAAGTACACATCCTGATTTGGTTTCTCCCTGTTGTAATTTGAGATTTCCCAAATTAAGTCTTATAATGATTAGGTTTTGTTCTGAGT
TATTTCTAGAGAAAGAAAGTATTTTAGTATGTGTAAATTGTACAATAATTTTTTTGCTGTTGTACTCACTGCTAATAGTGGATTGTATAG
GGTGGTGTTTTTATTTCATTTATTGTAGACAAAAATAATGAATTTAGTATACACATACCCACTAATTCAAGTATGTCAGAGCACAAAGTT
GGCAGCTGGTTATATTTAATTCAGCCCCTCTGAAAAGCACATACAGTCTATACTTTGTTTATAAATACCCTAGGTCCTCCCTGCCCCTAA
ATATATATTTTGGTGAAGCTGTGGTGCACTATTAATTTTCTGTTTCAAAATGCAATCTAAAGATGCAATAAATATGATGACCTTGATAGT
TTTAATGAAATCTTCAATTCTTGCAGCTGTGTTTTGGAAAGTGATTAAGCAATATTTCTCAAACCTGATGATTCTTGGATATTTAGCTAT
TGTCCTCCAAAGAGTCATCGTTTCACGTTTTCAAACATGTGCTTTGTGCTGAAGATTCTTGTCAGATATCCTGTGCTTCCAGAGTATTTT
TATCTTCAATTTTATTTAATTTTGTTTCATTTTGTTTTCATAAGACAATGTTTCAGATATGTAATGGGGCAAACCACTATAGATTTCTGT
TGGATAGAAAAATGAAATGTTACTAATAAGTTTAAATTGACCCTTCGTTGACTATCAGTACTGTTGATACATTTATTAGAATGTATGTCT
CAGAAGATGGTTTCTGTTTAAATTTATGGTCAAGTTACAACAACTGAATTCTAATATGGATTAAAAACTCCACATAAATATTTTTCCCCA
TGCGTCTTGGGTTATAATTTTCCTTTTAGACTTGCAAATATGCTTTTATTGCAATTTTGTCTCCATCTGTACTGTAGAATTACAAGCCTT
GTGCTCTTTATCTCTACATTTTCCACTTCTACATGATGCAATTAAGATGCCAATGAAAAGTATTGTGAACATTATTCTCAGGACACTTTT
ACCATACTTGAGTAGTACTAAGTCAGGTGTAACATGGAAAGCTAAGGGTTTCACCTTCTGATTTTGACATAATTGGAAATTTTCTATAAT
GGTAAGATGTTTATAGGAAAGTAATGGTAGTTCATGTTTGAGAATTTTTTTATTGCTTTCATTTCCCAGTTAAATGATATTTAACACCTG
GGAAAACAGGACAGCTCAGATTGTCGAGTTAGTAAACATGAGCGATGTAAAAACTTTATTTGAAATCTCCTAAGTGAGACATTAAACATT
TTAGTGCTAGTTTAAGCCATTAAAAGTAAAGTTTAAGTTTACGTCATTGTCTCAAGTGTGGCTGTAAAAATCAGATCTAGAGTTTAGAGA
CATACTTGTTAACTTTGGAGCACAGGTTTGATATTTATGCTTCTAAATACATTAAAACATTTCTGAATTGCAGTTGAATGGTTGGAGATT
GCTGGCGATGTGATGCTGCACTGAAAAAACTGGTCACACAAAATGTTTATATGTTTGACTGCATAAGTATTATTTTAGGTCATAAAGGTT
ATAACAAAATACATTTAACATTGCTTTCTTTTTAGCAAGAGGTCACAGATGCTATTTTTTCTCAGTTTTTAATGCTTTAATTTGAAAGAA
AAATGCATCCTAACCATTCCATCCTGTTGGTGCAGAGAAATTTTGGTGATTTATTAGAAGACTTTTAAGGAGGGTGGATACATAGTTTTT
CAACTGCAAAAATCATGTCATCTCTTCAGTAACTGTTAAAGTGTAATTCTCTGCCTTCATTATCAAGTCCAGGACAGTGTTTATTTTGAA
TCGTTAACATTATTTAAAGACTGAAAATTCATTGCAATTAGGGAACGCACAGCCTCACAAAAAGTGGTTGTGATTGCAAGGATTCTTTAT
GTCAGTGAACTTAAAAAGGGAATGGGGGAAGAGATGCATGCCTTTCTAAAGGTATGCTAGAGTCACCTGTGTAGCATTGTAATTATGTAC
TATCAAACCCCCAAGATGCTGATGATAGGCCTTCTCTGTAAGAATCCTTCTCATAGTGAAGCACTGTTGATGTTTTGTTCACCGGATATG
TTGGGTAGCAGAAAAGGCCTAGAACCAGTTTTAAGATTATGCCTACATCTCTAGAAGACTAGTACACTGGCATCATCTTAGGTTTCTAAA
TATTATTTAATTCCTTAATTTGGAAAGCAGTTTTAATGTTTACAGTTTAAGATACTCATTTTCAGTAACTAGTGTTAAAGATTTTTATCT
TTGCCTGTCTACTGTAACTTAAGACTTTCATAGAATAATTTTTTATAGAGTATATGGTATATTGTGTCAATCTTGGAAGGAAAGCTGTTG
CATATCAATTGTAGGTCATGTATTTTACTATATGTTGCATAGTATTTTGCATTCTGTAAATACGAATGTTAAAACATTTCAGGTCAGCAA
AATTAGAAGTCATTTCTAGTCCTCAAAGCAGAAATAATTAGAAATGTTAACATTTAAGTGCTTATCATATGCCAGATACTATTCTGAATA
TTTTATGTATATTCATTCATTTAGTTGTCATATTGGCTTTATGTGACATAACTGTCATTATACCAGTGTTGTCCAAGGTTGCTAGCAGGA
AATGGCAGAGCCAGGAGTTGGACCTAGGTTTAATCCTATCCATATTCCATGTTACAAATTGACATGATTTTCCATATTAAAAAATTTTCA
TTTATTTTGTACCTCATTCACATGAATAGTAATGTGACAAACTAAAGTTAATACATGAAGCATTGCAATATGGAATTTTGCACATTTTTG
TTAGCTTTACATTATTTGCTGATACCAACTTTTGGTAGGAAGGAAAACAGGGAAGGTGATTGCTGCTATTCTGGAATGTGTCCATTGAAA
AGAAAATAGGCGCTTTGTCTCCTACAATCTTAGAGAAAGTTTTACATACTTAAGTGGGTACCACAGATAGGCATGTACCTTAAATTCAAA
TCTACAGTTTTACAAAATGTTTTCCTTTGTGTGCCTTTCCTATGTCAAATTAGCCAGAAGGAAGAAGAGACGTTAAGAATGGCAGATAAA
TTTAACAGGTAATGATACAGAGATTGGCCATTACGCCAGCTCTCAGGAGAAAAACAACTAGGATGTCTTGAAACCCGTGCATTTAATTTT
AGAAATGGCAAATTTGTAAGCGTGTCATTTAAGTAATTTGATGCTCAGTTTTAGGGTCTAAGTTGACCTCGAGTGAGCCATGCAAAAATA
GCTTTAAAATTATACATGAGCAGCTCAAAGTAAACGTGTATTTTTTAGTAACAATGAAATTGTCAAATTTCAAGATTTTAATAACAGGAC

>85419_85419_2_SPAG16-CUL3_SPAG16_chr2_214162081_ENST00000272898_CUL3_chr2_225346795_ENST00000344951_length(amino acids)=247AA_BP=93
MAAQRGMPSSAVRVLEEALGMGLTAAGDARDTADAVAAEGAYYLEQVTITEASEDDYEYEEIPDDNFSIPEGEEDLAKAIQMAQEQATDT
EILEIQQETDIPERELVRALQSLACGKPTQRVLTKEPKSKEIENGHIFTVNDQFTSKLHRVKIQTVAAKQGESDPERKETRQKVDDDRKH

--------------------------------------------------------------
>85419_85419_3_SPAG16-CUL3_SPAG16_chr2_214162081_ENST00000272898_CUL3_chr2_225346795_ENST00000409096_length(transcript)=1071nt_BP=283nt
AGAGATGGCTGCTCAGCGAGGGATGCCCAGCTCCGCCGTGAGGGTCCTGGAAGAGGCGTTGGGCATGGGTTTGACGGCAGCCGGGGACGC
GAGGGACACGGCGGACGCGGTGGCGGCTGAGGGCGCCTACTACCTGGAACAGGTCACCATAACTGAAGCATCTGAAGATGACTATGAATA
TGAAGAGATACCAGATGACAATTTTAGCATCCCAGAAGGTGAAGAAGATCTGGCAAAAGCAATTCAGATGGCCCAAGAACAGGCTACAGA
TACTGAAATTTTGGAAATTCAGCAAGAGACAGATATCCCTGAAAGAGAGCTTGTTAGAGCCCTACAGTCCCTCGCCTGTGGTAAACCAAC
ACAGCGGGTTCTTACAAAAGAACCCAAATCAAAGGAAATAGAAAATGGTCATATATTTACAGTTAATGATCAATTCACATCCAAACTACA
CAGAGTCAAGATTCAAACAGTTGCTGCCAAACAAGGTGAATCCGACCCAGAGAGGAAAGAAACAAGGCAGAAAGTAGACGACGACAGAAA
ACATGAGATAGAAGCTGCTATAGTGCGGATAATGAAATCTAGAAAGAAGATGCAGCACAATGTTCTAGTAGCGGAGGTAACTCAGCAGTT
GAAGGCGCGATTCTTACCAAGTCCAGTTGTTATTAAGAAACGTATTGAAGGACTTATTGAGAGAGAATATTTGGCACGAACACCTGAGGA
TCGCAAAGTATACACATATGTAGCATAAAATGCGTTCAGAAATTTGATTTATTCTTGGACTGTACTCTTCGCATGGACTGGGAAGTTCTT
TTAAATCATTAAATATTAAGACGACCATCTCTTCTATTAAATTACAGTACATGTTCTAGACCATTGAGATCAAGCCTTTACTCCCTTTGA
GAGTTTCCAACATCAGTTGATTGAGCTTCAGGCTTTACAACGTTTATCCCTGTAGAGATCATCTTTACAGTTCCTCGGGAAAATGTGAAT

>85419_85419_3_SPAG16-CUL3_SPAG16_chr2_214162081_ENST00000272898_CUL3_chr2_225346795_ENST00000409096_length(amino acids)=247AA_BP=93
MAAQRGMPSSAVRVLEEALGMGLTAAGDARDTADAVAAEGAYYLEQVTITEASEDDYEYEEIPDDNFSIPEGEEDLAKAIQMAQEQATDT
EILEIQQETDIPERELVRALQSLACGKPTQRVLTKEPKSKEIENGHIFTVNDQFTSKLHRVKIQTVAAKQGESDPERKETRQKVDDDRKH

--------------------------------------------------------------
>85419_85419_4_SPAG16-CUL3_SPAG16_chr2_214162081_ENST00000272898_CUL3_chr2_225346795_ENST00000409777_length(transcript)=1054nt_BP=283nt
AGAGATGGCTGCTCAGCGAGGGATGCCCAGCTCCGCCGTGAGGGTCCTGGAAGAGGCGTTGGGCATGGGTTTGACGGCAGCCGGGGACGC
GAGGGACACGGCGGACGCGGTGGCGGCTGAGGGCGCCTACTACCTGGAACAGGTCACCATAACTGAAGCATCTGAAGATGACTATGAATA
TGAAGAGATACCAGATGACAATTTTAGCATCCCAGAAGGTGAAGAAGATCTGGCAAAAGCAATTCAGATGGCCCAAGAACAGGCTACAGA
TACTGAAATTTTGGAAATTCAGCAAGAGACAGATATCCCTGAAAGAGAGCTTGTTAGAGCCCTACAGTCCCTCGCCTGTGGTAAACCAAC
ACAGCGGGTTCTTACAAAAGAACCCAAATCAAAGGAAATAGAAAATGGTCATATATTTACAGTTAATGATCAATTCACATCCAAACTACA
CAGAGTCAAGATTCAAACAGTTGCTGCCAAACAAGGTGAATCCGACCCAGAGAGGAAAGAAACAAGGCAGAAAGTAGACGACGACAGAAA
ACATGAGATAGAAGCTGCTATAGTGCGGATAATGAAATCTAGAAAGAAGATGCAGCACAATGTTCTAGTAGCGGAGGTAACTCAGCAGTT
GAAGGCGCGATTCTTACCAAGTCCAGTTGTTATTAAGAAACGTATTGAAGGACTTATTGAGAGAGAATATTTGGCACGAACACCTGAGGA
TCGCAAAGTATACACATATGTAGCATAAAATGCGTTCAGAAATTTGATTTATTCTTGGACTGTACTCTTCGCATGGACTGGGAAGTTCTT
TTAAATCATTAAATATTAAGACGACCATCTCTTCTATTAAATTACAGTACATGTTCTAGACCATTGAGATCAAGCCTTTACTCCCTTTGA
GAGTTTCCAACATCAGTTGATTGAGCTTCAGGCTTTACAACGTTTATCCCTGTAGAGATCATCTTTACAGTTCCTCGGGAAAATGTGAAT

>85419_85419_4_SPAG16-CUL3_SPAG16_chr2_214162081_ENST00000272898_CUL3_chr2_225346795_ENST00000409777_length(amino acids)=247AA_BP=93
MAAQRGMPSSAVRVLEEALGMGLTAAGDARDTADAVAAEGAYYLEQVTITEASEDDYEYEEIPDDNFSIPEGEEDLAKAIQMAQEQATDT
EILEIQQETDIPERELVRALQSLACGKPTQRVLTKEPKSKEIENGHIFTVNDQFTSKLHRVKIQTVAAKQGESDPERKETRQKVDDDRKH

--------------------------------------------------------------
>85419_85419_5_SPAG16-CUL3_SPAG16_chr2_214162081_ENST00000331683_CUL3_chr2_225346795_ENST00000264414_length(transcript)=4934nt_BP=374nt
CGCGAGAGCTCCCGGGGGCCGTTGGGTAGCGTCTTCGCTGTTGCCCTTAGGGACGGCTGTGGGCCTGCTGGGGGTGGGGGCCCGAAGCGC
CAGAGATGGCTGCTCAGCGAGGGATGCCCAGCTCCGCCGTGAGGGTCCTGGAAGAGGCGTTGGGCATGGGTTTGACGGCAGCCGGGGACG
CGAGGGACACGGCGGACGCGGTGGCGGCTGAGGGCGCCTACTACCTGGAACAGGTCACCATAACTGAAGCATCTGAAGATGACTATGAAT
ATGAAGAGATACCAGATGACAATTTTAGCATCCCAGAAGGTGAAGAAGATCTGGCAAAAGCAATTCAGATGGCCCAAGAACAGGCTACAG
ATACTGAAATTTTGGAAATTCAGCAAGAGACAGATATCCCTGAAAGAGAGCTTGTTAGAGCCCTACAGTCCCTCGCCTGTGGTAAACCAA
CACAGCGGGTTCTTACAAAAGAACCCAAATCAAAGGAAATAGAAAATGGTCATATATTTACAGTTAATGATCAATTCACATCCAAACTAC
ACAGAGTCAAGATTCAAACAGTTGCTGCCAAACAAGGTGAATCCGACCCAGAGAGGAAAGAAACAAGGCAGAAAGTAGACGACGACAGAA
AACATGAGATAGAAGCTGCTATAGTGCGGATAATGAAATCTAGAAAGAAGATGCAGCACAATGTTCTAGTAGCGGAGGTAACTCAGCAGT
TGAAGGCGCGATTCTTACCAAGTCCAGTTGTTATTAAGAAACGTATTGAAGGACTTATTGAGAGAGAATATTTGGCACGAACACCTGAGG
ATCGCAAAGTATACACATATGTAGCATAAAATGCGTTCAGAAATTTGATTTATTCTTGGACTGTACTCTTCGCATGGACTGGGAAGTTCT
TTTAAATCATTAAATATTAAGACGACCATCTCTTCTATTAAATTACAGTACATGTTCTAGACCATTGAGATCAAGCCTTTACTCCCTTTG
AGAGTTTCCAACATCAGTTGATTGAGCTTCAGGCTTTACAACGTTTATCCCTGTAGAGATCATCTTTACAGTTCCTCGGGAAAATGTGAA
TGTGCTGCGTTTTGTTTTCTTTACTGTATGAAAACAGGAAAATAAAAGAGAAATTTAGAAAATACAGCTCATTACAATAAAATTGTTGGA
TTTCATTTCCCCAGGTCTTCAGTGTTGATGTAAATGTGTTTTGTAGTGTTGCTTAGCACTTTGCGCATTGTGTAAGTTGGGTAACAAAAA
TGGCAAAAGAAATGCAGATTTCCCAGTTATCTTGCTCTGAAGACATTTCTTTAGCTAGTCTTATTTAATTTTAAAGGTTTGATAAATATA
CAAAGACCCAAGCATACAATTTGAGCATGCTGTATTCTACCACTTGCACTTACTCATCTTCTAGCCTTATGACCAGGAACCTTTGTTTTG
GGCTCAAGTACACATCCTGATTTGGTTTCTCCCTGTTGTAATTTGAGATTTCCCAAATTAAGTCTTATAATGATTAGGTTTTGTTCTGAG
TTATTTCTAGAGAAAGAAAGTATTTTAGTATGTGTAAATTGTACAATAATTTTTTTGCTGTTGTACTCACTGCTAATAGTGGATTGTATA
GGGTGGTGTTTTTATTTCATTTATTGTAGACAAAAATAATGAATTTAGTATACACATACCCACTAATTCAAGTATGTCAGAGCACAAAGT
TGGCAGCTGGTTATATTTAATTCAGCCCCTCTGAAAAGCACATACAGTCTATACTTTGTTTATAAATACCCTAGGTCCTCCCTGCCCCTA
AATATATATTTTGGTGAAGCTGTGGTGCACTATTAATTTTCTGTTTCAAAATGCAATCTAAAGATGCAATAAATATGATGACCTTGATAG
TTTTAATGAAATCTTCAATTCTTGCAGCTGTGTTTTGGAAAGTGATTAAGCAATATTTCTCAAACCTGATGATTCTTGGATATTTAGCTA
TTGTCCTCCAAAGAGTCATCGTTTCACGTTTTCAAACATGTGCTTTGTGCTGAAGATTCTTGTCAGATATCCTGTGCTTCCAGAGTATTT
TTATCTTCAATTTTATTTAATTTTGTTTCATTTTGTTTTCATAAGACAATGTTTCAGATATGTAATGGGGCAAACCACTATAGATTTCTG
TTGGATAGAAAAATGAAATGTTACTAATAAGTTTAAATTGACCCTTCGTTGACTATCAGTACTGTTGATACATTTATTAGAATGTATGTC
TCAGAAGATGGTTTCTGTTTAAATTTATGGTCAAGTTACAACAACTGAATTCTAATATGGATTAAAAACTCCACATAAATATTTTTCCCC
ATGCGTCTTGGGTTATAATTTTCCTTTTAGACTTGCAAATATGCTTTTATTGCAATTTTGTCTCCATCTGTACTGTAGAATTACAAGCCT
TGTGCTCTTTATCTCTACATTTTCCACTTCTACATGATGCAATTAAGATGCCAATGAAAAGTATTGTGAACATTATTCTCAGGACACTTT
TACCATACTTGAGTAGTACTAAGTCAGGTGTAACATGGAAAGCTAAGGGTTTCACCTTCTGATTTTGACATAATTGGAAATTTTCTATAA
TGGTAAGATGTTTATAGGAAAGTAATGGTAGTTCATGTTTGAGAATTTTTTTATTGCTTTCATTTCCCAGTTAAATGATATTTAACACCT
GGGAAAACAGGACAGCTCAGATTGTCGAGTTAGTAAACATGAGCGATGTAAAAACTTTATTTGAAATCTCCTAAGTGAGACATTAAACAT
TTTAGTGCTAGTTTAAGCCATTAAAAGTAAAGTTTAAGTTTACGTCATTGTCTCAAGTGTGGCTGTAAAAATCAGATCTAGAGTTTAGAG
ACATACTTGTTAACTTTGGAGCACAGGTTTGATATTTATGCTTCTAAATACATTAAAACATTTCTGAATTGCAGTTGAATGGTTGGAGAT
TGCTGGCGATGTGATGCTGCACTGAAAAAACTGGTCACACAAAATGTTTATATGTTTGACTGCATAAGTATTATTTTAGGTCATAAAGGT
TATAACAAAATACATTTAACATTGCTTTCTTTTTAGCAAGAGGTCACAGATGCTATTTTTTCTCAGTTTTTAATGCTTTAATTTGAAAGA
AAAATGCATCCTAACCATTCCATCCTGTTGGTGCAGAGAAATTTTGGTGATTTATTAGAAGACTTTTAAGGAGGGTGGATACATAGTTTT
TCAACTGCAAAAATCATGTCATCTCTTCAGTAACTGTTAAAGTGTAATTCTCTGCCTTCATTATCAAGTCCAGGACAGTGTTTATTTTGA
ATCGTTAACATTATTTAAAGACTGAAAATTCATTGCAATTAGGGAACGCACAGCCTCACAAAAAGTGGTTGTGATTGCAAGGATTCTTTA
TGTCAGTGAACTTAAAAAGGGAATGGGGGAAGAGATGCATGCCTTTCTAAAGGTATGCTAGAGTCACCTGTGTAGCATTGTAATTATGTA
CTATCAAACCCCCAAGATGCTGATGATAGGCCTTCTCTGTAAGAATCCTTCTCATAGTGAAGCACTGTTGATGTTTTGTTCACCGGATAT
GTTGGGTAGCAGAAAAGGCCTAGAACCAGTTTTAAGATTATGCCTACATCTCTAGAAGACTAGTACACTGGCATCATCTTAGGTTTCTAA
ATATTATTTAATTCCTTAATTTGGAAAGCAGTTTTAATGTTTACAGTTTAAGATACTCATTTTCAGTAACTAGTGTTAAAGATTTTTATC
TTTGCCTGTCTACTGTAACTTAAGACTTTCATAGAATAATTTTTTATAGAGTATATGGTATATTGTGTCAATCTTGGAAGGAAAGCTGTT
GCATATCAATTGTAGGTCATGTATTTTACTATATGTTGCATAGTATTTTGCATTCTGTAAATACGAATGTTAAAACATTTCAGGTCAGCA
AAATTAGAAGTCATTTCTAGTCCTCAAAGCAGAAATAATTAGAAATGTTAACATTTAAGTGCTTATCATATGCCAGATACTATTCTGAAT
ATTTTATGTATATTCATTCATTTAGTTGTCATATTGGCTTTATGTGACATAACTGTCATTATACCAGTGTTGTCCAAGGTTGCTAGCAGG
AAATGGCAGAGCCAGGAGTTGGACCTAGGTTTAATCCTATCCATATTCCATGTTACAAATTGACATGATTTTCCATATTAAAAAATTTTC
ATTTATTTTGTACCTCATTCACATGAATAGTAATGTGACAAACTAAAGTTAATACATGAAGCATTGCAATATGGAATTTTGCACATTTTT
GTTAGCTTTACATTATTTGCTGATACCAACTTTTGGTAGGAAGGAAAACAGGGAAGGTGATTGCTGCTATTCTGGAATGTGTCCATTGAA
AAGAAAATAGGCGCTTTGTCTCCTACAATCTTAGAGAAAGTTTTACATACTTAAGTGGGTACCACAGATAGGCATGTACCTTAAATTCAA
ATCTACAGTTTTACAAAATGTTTTCCTTTGTGTGCCTTTCCTATGTCAAATTAGCCAGAAGGAAGAAGAGACGTTAAGAATGGCAGATAA
ATTTAACAGGTAATGATACAGAGATTGGCCATTACGCCAGCTCTCAGGAGAAAAACAACTAGGATGTCTTGAAACCCGTGCATTTAATTT
TAGAAATGGCAAATTTGTAAGCGTGTCATTTAAGTAATTTGATGCTCAGTTTTAGGGTCTAAGTTGACCTCGAGTGAGCCATGCAAAAAT
AGCTTTAAAATTATACATGAGCAGCTCAAAGTAAACGTGTATTTTTTAGTAACAATGAAATTGTCAAATTTCAAGATTTTAATAACAGGA

>85419_85419_5_SPAG16-CUL3_SPAG16_chr2_214162081_ENST00000331683_CUL3_chr2_225346795_ENST00000264414_length(amino acids)=260AA_BP=106
MWACWGWGPEAPEMAAQRGMPSSAVRVLEEALGMGLTAAGDARDTADAVAAEGAYYLEQVTITEASEDDYEYEEIPDDNFSIPEGEEDLA
KAIQMAQEQATDTEILEIQQETDIPERELVRALQSLACGKPTQRVLTKEPKSKEIENGHIFTVNDQFTSKLHRVKIQTVAAKQGESDPER

--------------------------------------------------------------
>85419_85419_6_SPAG16-CUL3_SPAG16_chr2_214162081_ENST00000331683_CUL3_chr2_225346795_ENST00000344951_length(transcript)=4932nt_BP=374nt
CGCGAGAGCTCCCGGGGGCCGTTGGGTAGCGTCTTCGCTGTTGCCCTTAGGGACGGCTGTGGGCCTGCTGGGGGTGGGGGCCCGAAGCGC
CAGAGATGGCTGCTCAGCGAGGGATGCCCAGCTCCGCCGTGAGGGTCCTGGAAGAGGCGTTGGGCATGGGTTTGACGGCAGCCGGGGACG
CGAGGGACACGGCGGACGCGGTGGCGGCTGAGGGCGCCTACTACCTGGAACAGGTCACCATAACTGAAGCATCTGAAGATGACTATGAAT
ATGAAGAGATACCAGATGACAATTTTAGCATCCCAGAAGGTGAAGAAGATCTGGCAAAAGCAATTCAGATGGCCCAAGAACAGGCTACAG
ATACTGAAATTTTGGAAATTCAGCAAGAGACAGATATCCCTGAAAGAGAGCTTGTTAGAGCCCTACAGTCCCTCGCCTGTGGTAAACCAA
CACAGCGGGTTCTTACAAAAGAACCCAAATCAAAGGAAATAGAAAATGGTCATATATTTACAGTTAATGATCAATTCACATCCAAACTAC
ACAGAGTCAAGATTCAAACAGTTGCTGCCAAACAAGGTGAATCCGACCCAGAGAGGAAAGAAACAAGGCAGAAAGTAGACGACGACAGAA
AACATGAGATAGAAGCTGCTATAGTGCGGATAATGAAATCTAGAAAGAAGATGCAGCACAATGTTCTAGTAGCGGAGGTAACTCAGCAGT
TGAAGGCGCGATTCTTACCAAGTCCAGTTGTTATTAAGAAACGTATTGAAGGACTTATTGAGAGAGAATATTTGGCACGAACACCTGAGG
ATCGCAAAGTATACACATATGTAGCATAAAATGCGTTCAGAAATTTGATTTATTCTTGGACTGTACTCTTCGCATGGACTGGGAAGTTCT
TTTAAATCATTAAATATTAAGACGACCATCTCTTCTATTAAATTACAGTACATGTTCTAGACCATTGAGATCAAGCCTTTACTCCCTTTG
AGAGTTTCCAACATCAGTTGATTGAGCTTCAGGCTTTACAACGTTTATCCCTGTAGAGATCATCTTTACAGTTCCTCGGGAAAATGTGAA
TGTGCTGCGTTTTGTTTTCTTTACTGTATGAAAACAGGAAAATAAAAGAGAAATTTAGAAAATACAGCTCATTACAATAAAATTGTTGGA
TTTCATTTCCCCAGGTCTTCAGTGTTGATGTAAATGTGTTTTGTAGTGTTGCTTAGCACTTTGCGCATTGTGTAAGTTGGGTAACAAAAA
TGGCAAAAGAAATGCAGATTTCCCAGTTATCTTGCTCTGAAGACATTTCTTTAGCTAGTCTTATTTAATTTTAAAGGTTTGATAAATATA
CAAAGACCCAAGCATACAATTTGAGCATGCTGTATTCTACCACTTGCACTTACTCATCTTCTAGCCTTATGACCAGGAACCTTTGTTTTG
GGCTCAAGTACACATCCTGATTTGGTTTCTCCCTGTTGTAATTTGAGATTTCCCAAATTAAGTCTTATAATGATTAGGTTTTGTTCTGAG
TTATTTCTAGAGAAAGAAAGTATTTTAGTATGTGTAAATTGTACAATAATTTTTTTGCTGTTGTACTCACTGCTAATAGTGGATTGTATA
GGGTGGTGTTTTTATTTCATTTATTGTAGACAAAAATAATGAATTTAGTATACACATACCCACTAATTCAAGTATGTCAGAGCACAAAGT
TGGCAGCTGGTTATATTTAATTCAGCCCCTCTGAAAAGCACATACAGTCTATACTTTGTTTATAAATACCCTAGGTCCTCCCTGCCCCTA
AATATATATTTTGGTGAAGCTGTGGTGCACTATTAATTTTCTGTTTCAAAATGCAATCTAAAGATGCAATAAATATGATGACCTTGATAG
TTTTAATGAAATCTTCAATTCTTGCAGCTGTGTTTTGGAAAGTGATTAAGCAATATTTCTCAAACCTGATGATTCTTGGATATTTAGCTA
TTGTCCTCCAAAGAGTCATCGTTTCACGTTTTCAAACATGTGCTTTGTGCTGAAGATTCTTGTCAGATATCCTGTGCTTCCAGAGTATTT
TTATCTTCAATTTTATTTAATTTTGTTTCATTTTGTTTTCATAAGACAATGTTTCAGATATGTAATGGGGCAAACCACTATAGATTTCTG
TTGGATAGAAAAATGAAATGTTACTAATAAGTTTAAATTGACCCTTCGTTGACTATCAGTACTGTTGATACATTTATTAGAATGTATGTC
TCAGAAGATGGTTTCTGTTTAAATTTATGGTCAAGTTACAACAACTGAATTCTAATATGGATTAAAAACTCCACATAAATATTTTTCCCC
ATGCGTCTTGGGTTATAATTTTCCTTTTAGACTTGCAAATATGCTTTTATTGCAATTTTGTCTCCATCTGTACTGTAGAATTACAAGCCT
TGTGCTCTTTATCTCTACATTTTCCACTTCTACATGATGCAATTAAGATGCCAATGAAAAGTATTGTGAACATTATTCTCAGGACACTTT
TACCATACTTGAGTAGTACTAAGTCAGGTGTAACATGGAAAGCTAAGGGTTTCACCTTCTGATTTTGACATAATTGGAAATTTTCTATAA
TGGTAAGATGTTTATAGGAAAGTAATGGTAGTTCATGTTTGAGAATTTTTTTATTGCTTTCATTTCCCAGTTAAATGATATTTAACACCT
GGGAAAACAGGACAGCTCAGATTGTCGAGTTAGTAAACATGAGCGATGTAAAAACTTTATTTGAAATCTCCTAAGTGAGACATTAAACAT
TTTAGTGCTAGTTTAAGCCATTAAAAGTAAAGTTTAAGTTTACGTCATTGTCTCAAGTGTGGCTGTAAAAATCAGATCTAGAGTTTAGAG
ACATACTTGTTAACTTTGGAGCACAGGTTTGATATTTATGCTTCTAAATACATTAAAACATTTCTGAATTGCAGTTGAATGGTTGGAGAT
TGCTGGCGATGTGATGCTGCACTGAAAAAACTGGTCACACAAAATGTTTATATGTTTGACTGCATAAGTATTATTTTAGGTCATAAAGGT
TATAACAAAATACATTTAACATTGCTTTCTTTTTAGCAAGAGGTCACAGATGCTATTTTTTCTCAGTTTTTAATGCTTTAATTTGAAAGA
AAAATGCATCCTAACCATTCCATCCTGTTGGTGCAGAGAAATTTTGGTGATTTATTAGAAGACTTTTAAGGAGGGTGGATACATAGTTTT
TCAACTGCAAAAATCATGTCATCTCTTCAGTAACTGTTAAAGTGTAATTCTCTGCCTTCATTATCAAGTCCAGGACAGTGTTTATTTTGA
ATCGTTAACATTATTTAAAGACTGAAAATTCATTGCAATTAGGGAACGCACAGCCTCACAAAAAGTGGTTGTGATTGCAAGGATTCTTTA
TGTCAGTGAACTTAAAAAGGGAATGGGGGAAGAGATGCATGCCTTTCTAAAGGTATGCTAGAGTCACCTGTGTAGCATTGTAATTATGTA
CTATCAAACCCCCAAGATGCTGATGATAGGCCTTCTCTGTAAGAATCCTTCTCATAGTGAAGCACTGTTGATGTTTTGTTCACCGGATAT
GTTGGGTAGCAGAAAAGGCCTAGAACCAGTTTTAAGATTATGCCTACATCTCTAGAAGACTAGTACACTGGCATCATCTTAGGTTTCTAA
ATATTATTTAATTCCTTAATTTGGAAAGCAGTTTTAATGTTTACAGTTTAAGATACTCATTTTCAGTAACTAGTGTTAAAGATTTTTATC
TTTGCCTGTCTACTGTAACTTAAGACTTTCATAGAATAATTTTTTATAGAGTATATGGTATATTGTGTCAATCTTGGAAGGAAAGCTGTT
GCATATCAATTGTAGGTCATGTATTTTACTATATGTTGCATAGTATTTTGCATTCTGTAAATACGAATGTTAAAACATTTCAGGTCAGCA
AAATTAGAAGTCATTTCTAGTCCTCAAAGCAGAAATAATTAGAAATGTTAACATTTAAGTGCTTATCATATGCCAGATACTATTCTGAAT
ATTTTATGTATATTCATTCATTTAGTTGTCATATTGGCTTTATGTGACATAACTGTCATTATACCAGTGTTGTCCAAGGTTGCTAGCAGG
AAATGGCAGAGCCAGGAGTTGGACCTAGGTTTAATCCTATCCATATTCCATGTTACAAATTGACATGATTTTCCATATTAAAAAATTTTC
ATTTATTTTGTACCTCATTCACATGAATAGTAATGTGACAAACTAAAGTTAATACATGAAGCATTGCAATATGGAATTTTGCACATTTTT
GTTAGCTTTACATTATTTGCTGATACCAACTTTTGGTAGGAAGGAAAACAGGGAAGGTGATTGCTGCTATTCTGGAATGTGTCCATTGAA
AAGAAAATAGGCGCTTTGTCTCCTACAATCTTAGAGAAAGTTTTACATACTTAAGTGGGTACCACAGATAGGCATGTACCTTAAATTCAA
ATCTACAGTTTTACAAAATGTTTTCCTTTGTGTGCCTTTCCTATGTCAAATTAGCCAGAAGGAAGAAGAGACGTTAAGAATGGCAGATAA
ATTTAACAGGTAATGATACAGAGATTGGCCATTACGCCAGCTCTCAGGAGAAAAACAACTAGGATGTCTTGAAACCCGTGCATTTAATTT
TAGAAATGGCAAATTTGTAAGCGTGTCATTTAAGTAATTTGATGCTCAGTTTTAGGGTCTAAGTTGACCTCGAGTGAGCCATGCAAAAAT
AGCTTTAAAATTATACATGAGCAGCTCAAAGTAAACGTGTATTTTTTAGTAACAATGAAATTGTCAAATTTCAAGATTTTAATAACAGGA

>85419_85419_6_SPAG16-CUL3_SPAG16_chr2_214162081_ENST00000331683_CUL3_chr2_225346795_ENST00000344951_length(amino acids)=260AA_BP=106
MWACWGWGPEAPEMAAQRGMPSSAVRVLEEALGMGLTAAGDARDTADAVAAEGAYYLEQVTITEASEDDYEYEEIPDDNFSIPEGEEDLA
KAIQMAQEQATDTEILEIQQETDIPERELVRALQSLACGKPTQRVLTKEPKSKEIENGHIFTVNDQFTSKLHRVKIQTVAAKQGESDPER

--------------------------------------------------------------
>85419_85419_7_SPAG16-CUL3_SPAG16_chr2_214162081_ENST00000331683_CUL3_chr2_225346795_ENST00000409096_length(transcript)=1162nt_BP=374nt
CGCGAGAGCTCCCGGGGGCCGTTGGGTAGCGTCTTCGCTGTTGCCCTTAGGGACGGCTGTGGGCCTGCTGGGGGTGGGGGCCCGAAGCGC
CAGAGATGGCTGCTCAGCGAGGGATGCCCAGCTCCGCCGTGAGGGTCCTGGAAGAGGCGTTGGGCATGGGTTTGACGGCAGCCGGGGACG
CGAGGGACACGGCGGACGCGGTGGCGGCTGAGGGCGCCTACTACCTGGAACAGGTCACCATAACTGAAGCATCTGAAGATGACTATGAAT
ATGAAGAGATACCAGATGACAATTTTAGCATCCCAGAAGGTGAAGAAGATCTGGCAAAAGCAATTCAGATGGCCCAAGAACAGGCTACAG
ATACTGAAATTTTGGAAATTCAGCAAGAGACAGATATCCCTGAAAGAGAGCTTGTTAGAGCCCTACAGTCCCTCGCCTGTGGTAAACCAA
CACAGCGGGTTCTTACAAAAGAACCCAAATCAAAGGAAATAGAAAATGGTCATATATTTACAGTTAATGATCAATTCACATCCAAACTAC
ACAGAGTCAAGATTCAAACAGTTGCTGCCAAACAAGGTGAATCCGACCCAGAGAGGAAAGAAACAAGGCAGAAAGTAGACGACGACAGAA
AACATGAGATAGAAGCTGCTATAGTGCGGATAATGAAATCTAGAAAGAAGATGCAGCACAATGTTCTAGTAGCGGAGGTAACTCAGCAGT
TGAAGGCGCGATTCTTACCAAGTCCAGTTGTTATTAAGAAACGTATTGAAGGACTTATTGAGAGAGAATATTTGGCACGAACACCTGAGG
ATCGCAAAGTATACACATATGTAGCATAAAATGCGTTCAGAAATTTGATTTATTCTTGGACTGTACTCTTCGCATGGACTGGGAAGTTCT
TTTAAATCATTAAATATTAAGACGACCATCTCTTCTATTAAATTACAGTACATGTTCTAGACCATTGAGATCAAGCCTTTACTCCCTTTG
AGAGTTTCCAACATCAGTTGATTGAGCTTCAGGCTTTACAACGTTTATCCCTGTAGAGATCATCTTTACAGTTCCTCGGGAAAATGTGAA

>85419_85419_7_SPAG16-CUL3_SPAG16_chr2_214162081_ENST00000331683_CUL3_chr2_225346795_ENST00000409096_length(amino acids)=260AA_BP=106
MWACWGWGPEAPEMAAQRGMPSSAVRVLEEALGMGLTAAGDARDTADAVAAEGAYYLEQVTITEASEDDYEYEEIPDDNFSIPEGEEDLA
KAIQMAQEQATDTEILEIQQETDIPERELVRALQSLACGKPTQRVLTKEPKSKEIENGHIFTVNDQFTSKLHRVKIQTVAAKQGESDPER

--------------------------------------------------------------
>85419_85419_8_SPAG16-CUL3_SPAG16_chr2_214162081_ENST00000331683_CUL3_chr2_225346795_ENST00000409777_length(transcript)=1145nt_BP=374nt
CGCGAGAGCTCCCGGGGGCCGTTGGGTAGCGTCTTCGCTGTTGCCCTTAGGGACGGCTGTGGGCCTGCTGGGGGTGGGGGCCCGAAGCGC
CAGAGATGGCTGCTCAGCGAGGGATGCCCAGCTCCGCCGTGAGGGTCCTGGAAGAGGCGTTGGGCATGGGTTTGACGGCAGCCGGGGACG
CGAGGGACACGGCGGACGCGGTGGCGGCTGAGGGCGCCTACTACCTGGAACAGGTCACCATAACTGAAGCATCTGAAGATGACTATGAAT
ATGAAGAGATACCAGATGACAATTTTAGCATCCCAGAAGGTGAAGAAGATCTGGCAAAAGCAATTCAGATGGCCCAAGAACAGGCTACAG
ATACTGAAATTTTGGAAATTCAGCAAGAGACAGATATCCCTGAAAGAGAGCTTGTTAGAGCCCTACAGTCCCTCGCCTGTGGTAAACCAA
CACAGCGGGTTCTTACAAAAGAACCCAAATCAAAGGAAATAGAAAATGGTCATATATTTACAGTTAATGATCAATTCACATCCAAACTAC
ACAGAGTCAAGATTCAAACAGTTGCTGCCAAACAAGGTGAATCCGACCCAGAGAGGAAAGAAACAAGGCAGAAAGTAGACGACGACAGAA
AACATGAGATAGAAGCTGCTATAGTGCGGATAATGAAATCTAGAAAGAAGATGCAGCACAATGTTCTAGTAGCGGAGGTAACTCAGCAGT
TGAAGGCGCGATTCTTACCAAGTCCAGTTGTTATTAAGAAACGTATTGAAGGACTTATTGAGAGAGAATATTTGGCACGAACACCTGAGG
ATCGCAAAGTATACACATATGTAGCATAAAATGCGTTCAGAAATTTGATTTATTCTTGGACTGTACTCTTCGCATGGACTGGGAAGTTCT
TTTAAATCATTAAATATTAAGACGACCATCTCTTCTATTAAATTACAGTACATGTTCTAGACCATTGAGATCAAGCCTTTACTCCCTTTG
AGAGTTTCCAACATCAGTTGATTGAGCTTCAGGCTTTACAACGTTTATCCCTGTAGAGATCATCTTTACAGTTCCTCGGGAAAATGTGAA

>85419_85419_8_SPAG16-CUL3_SPAG16_chr2_214162081_ENST00000331683_CUL3_chr2_225346795_ENST00000409777_length(amino acids)=260AA_BP=106
MWACWGWGPEAPEMAAQRGMPSSAVRVLEEALGMGLTAAGDARDTADAVAAEGAYYLEQVTITEASEDDYEYEEIPDDNFSIPEGEEDLA
KAIQMAQEQATDTEILEIQQETDIPERELVRALQSLACGKPTQRVLTKEPKSKEIENGHIFTVNDQFTSKLHRVKIQTVAAKQGESDPER

--------------------------------------------------------------
>85419_85419_9_SPAG16-CUL3_SPAG16_chr2_214162081_ENST00000413312_CUL3_chr2_225346795_ENST00000264414_length(transcript)=4992nt_BP=432nt
AGCGTCTTCGCTGTTGCCCTTAGGGACGGCTGTGGGCCTGCTGGGGGTGGGGGCCCGAAGCGCCAGAGATGGCTGCTCAGCGAGGGATGC
CCAGCTCCGCCGTGAGGGTCCTGGAAGAGGCGTTGGGCATGGGTTTGACGGCAGCCGGGGACGCGAGGGACACGGCGGACGCGGTGGCGG
CTGAGGGCGCCTACTACCTGGAACGTATCCTTCCCGTGGAGGCGCGGCCCGCTGCGCTGGCGGGTAATGGGTGTTGGGACGAAGGCGAGG
GCCTCCCACTGGCGGCGCCTTTTGAGCCTTGGGGCCACTCCGGAGGAGCCTCTGTTGGACTTCAAGATACCAGATGACAATTTTAGCATC
CCAGAAGGTGAAGAAGATCTGGCAAAAGCAATTCAGATGGCCCAAGAACAGGCTACAGATACTGAAATTTTGGAAATTCAGCAAGAGACA
GATATCCCTGAAAGAGAGCTTGTTAGAGCCCTACAGTCCCTCGCCTGTGGTAAACCAACACAGCGGGTTCTTACAAAAGAACCCAAATCA
AAGGAAATAGAAAATGGTCATATATTTACAGTTAATGATCAATTCACATCCAAACTACACAGAGTCAAGATTCAAACAGTTGCTGCCAAA
CAAGGTGAATCCGACCCAGAGAGGAAAGAAACAAGGCAGAAAGTAGACGACGACAGAAAACATGAGATAGAAGCTGCTATAGTGCGGATA
ATGAAATCTAGAAAGAAGATGCAGCACAATGTTCTAGTAGCGGAGGTAACTCAGCAGTTGAAGGCGCGATTCTTACCAAGTCCAGTTGTT
ATTAAGAAACGTATTGAAGGACTTATTGAGAGAGAATATTTGGCACGAACACCTGAGGATCGCAAAGTATACACATATGTAGCATAAAAT
GCGTTCAGAAATTTGATTTATTCTTGGACTGTACTCTTCGCATGGACTGGGAAGTTCTTTTAAATCATTAAATATTAAGACGACCATCTC
TTCTATTAAATTACAGTACATGTTCTAGACCATTGAGATCAAGCCTTTACTCCCTTTGAGAGTTTCCAACATCAGTTGATTGAGCTTCAG
GCTTTACAACGTTTATCCCTGTAGAGATCATCTTTACAGTTCCTCGGGAAAATGTGAATGTGCTGCGTTTTGTTTTCTTTACTGTATGAA
AACAGGAAAATAAAAGAGAAATTTAGAAAATACAGCTCATTACAATAAAATTGTTGGATTTCATTTCCCCAGGTCTTCAGTGTTGATGTA
AATGTGTTTTGTAGTGTTGCTTAGCACTTTGCGCATTGTGTAAGTTGGGTAACAAAAATGGCAAAAGAAATGCAGATTTCCCAGTTATCT
TGCTCTGAAGACATTTCTTTAGCTAGTCTTATTTAATTTTAAAGGTTTGATAAATATACAAAGACCCAAGCATACAATTTGAGCATGCTG
TATTCTACCACTTGCACTTACTCATCTTCTAGCCTTATGACCAGGAACCTTTGTTTTGGGCTCAAGTACACATCCTGATTTGGTTTCTCC
CTGTTGTAATTTGAGATTTCCCAAATTAAGTCTTATAATGATTAGGTTTTGTTCTGAGTTATTTCTAGAGAAAGAAAGTATTTTAGTATG
TGTAAATTGTACAATAATTTTTTTGCTGTTGTACTCACTGCTAATAGTGGATTGTATAGGGTGGTGTTTTTATTTCATTTATTGTAGACA
AAAATAATGAATTTAGTATACACATACCCACTAATTCAAGTATGTCAGAGCACAAAGTTGGCAGCTGGTTATATTTAATTCAGCCCCTCT
GAAAAGCACATACAGTCTATACTTTGTTTATAAATACCCTAGGTCCTCCCTGCCCCTAAATATATATTTTGGTGAAGCTGTGGTGCACTA
TTAATTTTCTGTTTCAAAATGCAATCTAAAGATGCAATAAATATGATGACCTTGATAGTTTTAATGAAATCTTCAATTCTTGCAGCTGTG
TTTTGGAAAGTGATTAAGCAATATTTCTCAAACCTGATGATTCTTGGATATTTAGCTATTGTCCTCCAAAGAGTCATCGTTTCACGTTTT
CAAACATGTGCTTTGTGCTGAAGATTCTTGTCAGATATCCTGTGCTTCCAGAGTATTTTTATCTTCAATTTTATTTAATTTTGTTTCATT
TTGTTTTCATAAGACAATGTTTCAGATATGTAATGGGGCAAACCACTATAGATTTCTGTTGGATAGAAAAATGAAATGTTACTAATAAGT
TTAAATTGACCCTTCGTTGACTATCAGTACTGTTGATACATTTATTAGAATGTATGTCTCAGAAGATGGTTTCTGTTTAAATTTATGGTC
AAGTTACAACAACTGAATTCTAATATGGATTAAAAACTCCACATAAATATTTTTCCCCATGCGTCTTGGGTTATAATTTTCCTTTTAGAC
TTGCAAATATGCTTTTATTGCAATTTTGTCTCCATCTGTACTGTAGAATTACAAGCCTTGTGCTCTTTATCTCTACATTTTCCACTTCTA
CATGATGCAATTAAGATGCCAATGAAAAGTATTGTGAACATTATTCTCAGGACACTTTTACCATACTTGAGTAGTACTAAGTCAGGTGTA
ACATGGAAAGCTAAGGGTTTCACCTTCTGATTTTGACATAATTGGAAATTTTCTATAATGGTAAGATGTTTATAGGAAAGTAATGGTAGT
TCATGTTTGAGAATTTTTTTATTGCTTTCATTTCCCAGTTAAATGATATTTAACACCTGGGAAAACAGGACAGCTCAGATTGTCGAGTTA
GTAAACATGAGCGATGTAAAAACTTTATTTGAAATCTCCTAAGTGAGACATTAAACATTTTAGTGCTAGTTTAAGCCATTAAAAGTAAAG
TTTAAGTTTACGTCATTGTCTCAAGTGTGGCTGTAAAAATCAGATCTAGAGTTTAGAGACATACTTGTTAACTTTGGAGCACAGGTTTGA
TATTTATGCTTCTAAATACATTAAAACATTTCTGAATTGCAGTTGAATGGTTGGAGATTGCTGGCGATGTGATGCTGCACTGAAAAAACT
GGTCACACAAAATGTTTATATGTTTGACTGCATAAGTATTATTTTAGGTCATAAAGGTTATAACAAAATACATTTAACATTGCTTTCTTT
TTAGCAAGAGGTCACAGATGCTATTTTTTCTCAGTTTTTAATGCTTTAATTTGAAAGAAAAATGCATCCTAACCATTCCATCCTGTTGGT
GCAGAGAAATTTTGGTGATTTATTAGAAGACTTTTAAGGAGGGTGGATACATAGTTTTTCAACTGCAAAAATCATGTCATCTCTTCAGTA
ACTGTTAAAGTGTAATTCTCTGCCTTCATTATCAAGTCCAGGACAGTGTTTATTTTGAATCGTTAACATTATTTAAAGACTGAAAATTCA
TTGCAATTAGGGAACGCACAGCCTCACAAAAAGTGGTTGTGATTGCAAGGATTCTTTATGTCAGTGAACTTAAAAAGGGAATGGGGGAAG
AGATGCATGCCTTTCTAAAGGTATGCTAGAGTCACCTGTGTAGCATTGTAATTATGTACTATCAAACCCCCAAGATGCTGATGATAGGCC
TTCTCTGTAAGAATCCTTCTCATAGTGAAGCACTGTTGATGTTTTGTTCACCGGATATGTTGGGTAGCAGAAAAGGCCTAGAACCAGTTT
TAAGATTATGCCTACATCTCTAGAAGACTAGTACACTGGCATCATCTTAGGTTTCTAAATATTATTTAATTCCTTAATTTGGAAAGCAGT
TTTAATGTTTACAGTTTAAGATACTCATTTTCAGTAACTAGTGTTAAAGATTTTTATCTTTGCCTGTCTACTGTAACTTAAGACTTTCAT
AGAATAATTTTTTATAGAGTATATGGTATATTGTGTCAATCTTGGAAGGAAAGCTGTTGCATATCAATTGTAGGTCATGTATTTTACTAT
ATGTTGCATAGTATTTTGCATTCTGTAAATACGAATGTTAAAACATTTCAGGTCAGCAAAATTAGAAGTCATTTCTAGTCCTCAAAGCAG
AAATAATTAGAAATGTTAACATTTAAGTGCTTATCATATGCCAGATACTATTCTGAATATTTTATGTATATTCATTCATTTAGTTGTCAT
ATTGGCTTTATGTGACATAACTGTCATTATACCAGTGTTGTCCAAGGTTGCTAGCAGGAAATGGCAGAGCCAGGAGTTGGACCTAGGTTT
AATCCTATCCATATTCCATGTTACAAATTGACATGATTTTCCATATTAAAAAATTTTCATTTATTTTGTACCTCATTCACATGAATAGTA
ATGTGACAAACTAAAGTTAATACATGAAGCATTGCAATATGGAATTTTGCACATTTTTGTTAGCTTTACATTATTTGCTGATACCAACTT
TTGGTAGGAAGGAAAACAGGGAAGGTGATTGCTGCTATTCTGGAATGTGTCCATTGAAAAGAAAATAGGCGCTTTGTCTCCTACAATCTT
AGAGAAAGTTTTACATACTTAAGTGGGTACCACAGATAGGCATGTACCTTAAATTCAAATCTACAGTTTTACAAAATGTTTTCCTTTGTG
TGCCTTTCCTATGTCAAATTAGCCAGAAGGAAGAAGAGACGTTAAGAATGGCAGATAAATTTAACAGGTAATGATACAGAGATTGGCCAT
TACGCCAGCTCTCAGGAGAAAAACAACTAGGATGTCTTGAAACCCGTGCATTTAATTTTAGAAATGGCAAATTTGTAAGCGTGTCATTTA
AGTAATTTGATGCTCAGTTTTAGGGTCTAAGTTGACCTCGAGTGAGCCATGCAAAAATAGCTTTAAAATTATACATGAGCAGCTCAAAGT
AAACGTGTATTTTTTAGTAACAATGAAATTGTCAAATTTCAAGATTTTAATAACAGGACAGTTCAACTAATAAACTTTATTGCATACAAG

>85419_85419_9_SPAG16-CUL3_SPAG16_chr2_214162081_ENST00000413312_CUL3_chr2_225346795_ENST00000264414_length(amino acids)=238AA_BP=84
MRAPTTWNVSFPWRRGPLRWRVMGVGTKARASHWRRLLSLGATPEEPLLDFKIPDDNFSIPEGEEDLAKAIQMAQEQATDTEILEIQQET
DIPERELVRALQSLACGKPTQRVLTKEPKSKEIENGHIFTVNDQFTSKLHRVKIQTVAAKQGESDPERKETRQKVDDDRKHEIEAAIVRI

--------------------------------------------------------------
>85419_85419_10_SPAG16-CUL3_SPAG16_chr2_214162081_ENST00000413312_CUL3_chr2_225346795_ENST00000344951_length(transcript)=4990nt_BP=432nt
AGCGTCTTCGCTGTTGCCCTTAGGGACGGCTGTGGGCCTGCTGGGGGTGGGGGCCCGAAGCGCCAGAGATGGCTGCTCAGCGAGGGATGC
CCAGCTCCGCCGTGAGGGTCCTGGAAGAGGCGTTGGGCATGGGTTTGACGGCAGCCGGGGACGCGAGGGACACGGCGGACGCGGTGGCGG
CTGAGGGCGCCTACTACCTGGAACGTATCCTTCCCGTGGAGGCGCGGCCCGCTGCGCTGGCGGGTAATGGGTGTTGGGACGAAGGCGAGG
GCCTCCCACTGGCGGCGCCTTTTGAGCCTTGGGGCCACTCCGGAGGAGCCTCTGTTGGACTTCAAGATACCAGATGACAATTTTAGCATC
CCAGAAGGTGAAGAAGATCTGGCAAAAGCAATTCAGATGGCCCAAGAACAGGCTACAGATACTGAAATTTTGGAAATTCAGCAAGAGACA
GATATCCCTGAAAGAGAGCTTGTTAGAGCCCTACAGTCCCTCGCCTGTGGTAAACCAACACAGCGGGTTCTTACAAAAGAACCCAAATCA
AAGGAAATAGAAAATGGTCATATATTTACAGTTAATGATCAATTCACATCCAAACTACACAGAGTCAAGATTCAAACAGTTGCTGCCAAA
CAAGGTGAATCCGACCCAGAGAGGAAAGAAACAAGGCAGAAAGTAGACGACGACAGAAAACATGAGATAGAAGCTGCTATAGTGCGGATA
ATGAAATCTAGAAAGAAGATGCAGCACAATGTTCTAGTAGCGGAGGTAACTCAGCAGTTGAAGGCGCGATTCTTACCAAGTCCAGTTGTT
ATTAAGAAACGTATTGAAGGACTTATTGAGAGAGAATATTTGGCACGAACACCTGAGGATCGCAAAGTATACACATATGTAGCATAAAAT
GCGTTCAGAAATTTGATTTATTCTTGGACTGTACTCTTCGCATGGACTGGGAAGTTCTTTTAAATCATTAAATATTAAGACGACCATCTC
TTCTATTAAATTACAGTACATGTTCTAGACCATTGAGATCAAGCCTTTACTCCCTTTGAGAGTTTCCAACATCAGTTGATTGAGCTTCAG
GCTTTACAACGTTTATCCCTGTAGAGATCATCTTTACAGTTCCTCGGGAAAATGTGAATGTGCTGCGTTTTGTTTTCTTTACTGTATGAA
AACAGGAAAATAAAAGAGAAATTTAGAAAATACAGCTCATTACAATAAAATTGTTGGATTTCATTTCCCCAGGTCTTCAGTGTTGATGTA
AATGTGTTTTGTAGTGTTGCTTAGCACTTTGCGCATTGTGTAAGTTGGGTAACAAAAATGGCAAAAGAAATGCAGATTTCCCAGTTATCT
TGCTCTGAAGACATTTCTTTAGCTAGTCTTATTTAATTTTAAAGGTTTGATAAATATACAAAGACCCAAGCATACAATTTGAGCATGCTG
TATTCTACCACTTGCACTTACTCATCTTCTAGCCTTATGACCAGGAACCTTTGTTTTGGGCTCAAGTACACATCCTGATTTGGTTTCTCC
CTGTTGTAATTTGAGATTTCCCAAATTAAGTCTTATAATGATTAGGTTTTGTTCTGAGTTATTTCTAGAGAAAGAAAGTATTTTAGTATG
TGTAAATTGTACAATAATTTTTTTGCTGTTGTACTCACTGCTAATAGTGGATTGTATAGGGTGGTGTTTTTATTTCATTTATTGTAGACA
AAAATAATGAATTTAGTATACACATACCCACTAATTCAAGTATGTCAGAGCACAAAGTTGGCAGCTGGTTATATTTAATTCAGCCCCTCT
GAAAAGCACATACAGTCTATACTTTGTTTATAAATACCCTAGGTCCTCCCTGCCCCTAAATATATATTTTGGTGAAGCTGTGGTGCACTA
TTAATTTTCTGTTTCAAAATGCAATCTAAAGATGCAATAAATATGATGACCTTGATAGTTTTAATGAAATCTTCAATTCTTGCAGCTGTG
TTTTGGAAAGTGATTAAGCAATATTTCTCAAACCTGATGATTCTTGGATATTTAGCTATTGTCCTCCAAAGAGTCATCGTTTCACGTTTT
CAAACATGTGCTTTGTGCTGAAGATTCTTGTCAGATATCCTGTGCTTCCAGAGTATTTTTATCTTCAATTTTATTTAATTTTGTTTCATT
TTGTTTTCATAAGACAATGTTTCAGATATGTAATGGGGCAAACCACTATAGATTTCTGTTGGATAGAAAAATGAAATGTTACTAATAAGT
TTAAATTGACCCTTCGTTGACTATCAGTACTGTTGATACATTTATTAGAATGTATGTCTCAGAAGATGGTTTCTGTTTAAATTTATGGTC
AAGTTACAACAACTGAATTCTAATATGGATTAAAAACTCCACATAAATATTTTTCCCCATGCGTCTTGGGTTATAATTTTCCTTTTAGAC
TTGCAAATATGCTTTTATTGCAATTTTGTCTCCATCTGTACTGTAGAATTACAAGCCTTGTGCTCTTTATCTCTACATTTTCCACTTCTA
CATGATGCAATTAAGATGCCAATGAAAAGTATTGTGAACATTATTCTCAGGACACTTTTACCATACTTGAGTAGTACTAAGTCAGGTGTA
ACATGGAAAGCTAAGGGTTTCACCTTCTGATTTTGACATAATTGGAAATTTTCTATAATGGTAAGATGTTTATAGGAAAGTAATGGTAGT
TCATGTTTGAGAATTTTTTTATTGCTTTCATTTCCCAGTTAAATGATATTTAACACCTGGGAAAACAGGACAGCTCAGATTGTCGAGTTA
GTAAACATGAGCGATGTAAAAACTTTATTTGAAATCTCCTAAGTGAGACATTAAACATTTTAGTGCTAGTTTAAGCCATTAAAAGTAAAG
TTTAAGTTTACGTCATTGTCTCAAGTGTGGCTGTAAAAATCAGATCTAGAGTTTAGAGACATACTTGTTAACTTTGGAGCACAGGTTTGA
TATTTATGCTTCTAAATACATTAAAACATTTCTGAATTGCAGTTGAATGGTTGGAGATTGCTGGCGATGTGATGCTGCACTGAAAAAACT
GGTCACACAAAATGTTTATATGTTTGACTGCATAAGTATTATTTTAGGTCATAAAGGTTATAACAAAATACATTTAACATTGCTTTCTTT
TTAGCAAGAGGTCACAGATGCTATTTTTTCTCAGTTTTTAATGCTTTAATTTGAAAGAAAAATGCATCCTAACCATTCCATCCTGTTGGT
GCAGAGAAATTTTGGTGATTTATTAGAAGACTTTTAAGGAGGGTGGATACATAGTTTTTCAACTGCAAAAATCATGTCATCTCTTCAGTA
ACTGTTAAAGTGTAATTCTCTGCCTTCATTATCAAGTCCAGGACAGTGTTTATTTTGAATCGTTAACATTATTTAAAGACTGAAAATTCA
TTGCAATTAGGGAACGCACAGCCTCACAAAAAGTGGTTGTGATTGCAAGGATTCTTTATGTCAGTGAACTTAAAAAGGGAATGGGGGAAG
AGATGCATGCCTTTCTAAAGGTATGCTAGAGTCACCTGTGTAGCATTGTAATTATGTACTATCAAACCCCCAAGATGCTGATGATAGGCC
TTCTCTGTAAGAATCCTTCTCATAGTGAAGCACTGTTGATGTTTTGTTCACCGGATATGTTGGGTAGCAGAAAAGGCCTAGAACCAGTTT
TAAGATTATGCCTACATCTCTAGAAGACTAGTACACTGGCATCATCTTAGGTTTCTAAATATTATTTAATTCCTTAATTTGGAAAGCAGT
TTTAATGTTTACAGTTTAAGATACTCATTTTCAGTAACTAGTGTTAAAGATTTTTATCTTTGCCTGTCTACTGTAACTTAAGACTTTCAT
AGAATAATTTTTTATAGAGTATATGGTATATTGTGTCAATCTTGGAAGGAAAGCTGTTGCATATCAATTGTAGGTCATGTATTTTACTAT
ATGTTGCATAGTATTTTGCATTCTGTAAATACGAATGTTAAAACATTTCAGGTCAGCAAAATTAGAAGTCATTTCTAGTCCTCAAAGCAG
AAATAATTAGAAATGTTAACATTTAAGTGCTTATCATATGCCAGATACTATTCTGAATATTTTATGTATATTCATTCATTTAGTTGTCAT
ATTGGCTTTATGTGACATAACTGTCATTATACCAGTGTTGTCCAAGGTTGCTAGCAGGAAATGGCAGAGCCAGGAGTTGGACCTAGGTTT
AATCCTATCCATATTCCATGTTACAAATTGACATGATTTTCCATATTAAAAAATTTTCATTTATTTTGTACCTCATTCACATGAATAGTA
ATGTGACAAACTAAAGTTAATACATGAAGCATTGCAATATGGAATTTTGCACATTTTTGTTAGCTTTACATTATTTGCTGATACCAACTT
TTGGTAGGAAGGAAAACAGGGAAGGTGATTGCTGCTATTCTGGAATGTGTCCATTGAAAAGAAAATAGGCGCTTTGTCTCCTACAATCTT
AGAGAAAGTTTTACATACTTAAGTGGGTACCACAGATAGGCATGTACCTTAAATTCAAATCTACAGTTTTACAAAATGTTTTCCTTTGTG
TGCCTTTCCTATGTCAAATTAGCCAGAAGGAAGAAGAGACGTTAAGAATGGCAGATAAATTTAACAGGTAATGATACAGAGATTGGCCAT
TACGCCAGCTCTCAGGAGAAAAACAACTAGGATGTCTTGAAACCCGTGCATTTAATTTTAGAAATGGCAAATTTGTAAGCGTGTCATTTA
AGTAATTTGATGCTCAGTTTTAGGGTCTAAGTTGACCTCGAGTGAGCCATGCAAAAATAGCTTTAAAATTATACATGAGCAGCTCAAAGT
AAACGTGTATTTTTTAGTAACAATGAAATTGTCAAATTTCAAGATTTTAATAACAGGACAGTTCAACTAATAAACTTTATTGCATACAAG

>85419_85419_10_SPAG16-CUL3_SPAG16_chr2_214162081_ENST00000413312_CUL3_chr2_225346795_ENST00000344951_length(amino acids)=238AA_BP=84
MRAPTTWNVSFPWRRGPLRWRVMGVGTKARASHWRRLLSLGATPEEPLLDFKIPDDNFSIPEGEEDLAKAIQMAQEQATDTEILEIQQET
DIPERELVRALQSLACGKPTQRVLTKEPKSKEIENGHIFTVNDQFTSKLHRVKIQTVAAKQGESDPERKETRQKVDDDRKHEIEAAIVRI

--------------------------------------------------------------
>85419_85419_11_SPAG16-CUL3_SPAG16_chr2_214162081_ENST00000413312_CUL3_chr2_225346795_ENST00000409096_length(transcript)=1220nt_BP=432nt
AGCGTCTTCGCTGTTGCCCTTAGGGACGGCTGTGGGCCTGCTGGGGGTGGGGGCCCGAAGCGCCAGAGATGGCTGCTCAGCGAGGGATGC
CCAGCTCCGCCGTGAGGGTCCTGGAAGAGGCGTTGGGCATGGGTTTGACGGCAGCCGGGGACGCGAGGGACACGGCGGACGCGGTGGCGG
CTGAGGGCGCCTACTACCTGGAACGTATCCTTCCCGTGGAGGCGCGGCCCGCTGCGCTGGCGGGTAATGGGTGTTGGGACGAAGGCGAGG
GCCTCCCACTGGCGGCGCCTTTTGAGCCTTGGGGCCACTCCGGAGGAGCCTCTGTTGGACTTCAAGATACCAGATGACAATTTTAGCATC
CCAGAAGGTGAAGAAGATCTGGCAAAAGCAATTCAGATGGCCCAAGAACAGGCTACAGATACTGAAATTTTGGAAATTCAGCAAGAGACA
GATATCCCTGAAAGAGAGCTTGTTAGAGCCCTACAGTCCCTCGCCTGTGGTAAACCAACACAGCGGGTTCTTACAAAAGAACCCAAATCA
AAGGAAATAGAAAATGGTCATATATTTACAGTTAATGATCAATTCACATCCAAACTACACAGAGTCAAGATTCAAACAGTTGCTGCCAAA
CAAGGTGAATCCGACCCAGAGAGGAAAGAAACAAGGCAGAAAGTAGACGACGACAGAAAACATGAGATAGAAGCTGCTATAGTGCGGATA
ATGAAATCTAGAAAGAAGATGCAGCACAATGTTCTAGTAGCGGAGGTAACTCAGCAGTTGAAGGCGCGATTCTTACCAAGTCCAGTTGTT
ATTAAGAAACGTATTGAAGGACTTATTGAGAGAGAATATTTGGCACGAACACCTGAGGATCGCAAAGTATACACATATGTAGCATAAAAT
GCGTTCAGAAATTTGATTTATTCTTGGACTGTACTCTTCGCATGGACTGGGAAGTTCTTTTAAATCATTAAATATTAAGACGACCATCTC
TTCTATTAAATTACAGTACATGTTCTAGACCATTGAGATCAAGCCTTTACTCCCTTTGAGAGTTTCCAACATCAGTTGATTGAGCTTCAG
GCTTTACAACGTTTATCCCTGTAGAGATCATCTTTACAGTTCCTCGGGAAAATGTGAATGTGCTGCGTTTTGTTTTCTTTACTGTATGAA

>85419_85419_11_SPAG16-CUL3_SPAG16_chr2_214162081_ENST00000413312_CUL3_chr2_225346795_ENST00000409096_length(amino acids)=238AA_BP=84
MRAPTTWNVSFPWRRGPLRWRVMGVGTKARASHWRRLLSLGATPEEPLLDFKIPDDNFSIPEGEEDLAKAIQMAQEQATDTEILEIQQET
DIPERELVRALQSLACGKPTQRVLTKEPKSKEIENGHIFTVNDQFTSKLHRVKIQTVAAKQGESDPERKETRQKVDDDRKHEIEAAIVRI

--------------------------------------------------------------
>85419_85419_12_SPAG16-CUL3_SPAG16_chr2_214162081_ENST00000413312_CUL3_chr2_225346795_ENST00000409777_length(transcript)=1203nt_BP=432nt
AGCGTCTTCGCTGTTGCCCTTAGGGACGGCTGTGGGCCTGCTGGGGGTGGGGGCCCGAAGCGCCAGAGATGGCTGCTCAGCGAGGGATGC
CCAGCTCCGCCGTGAGGGTCCTGGAAGAGGCGTTGGGCATGGGTTTGACGGCAGCCGGGGACGCGAGGGACACGGCGGACGCGGTGGCGG
CTGAGGGCGCCTACTACCTGGAACGTATCCTTCCCGTGGAGGCGCGGCCCGCTGCGCTGGCGGGTAATGGGTGTTGGGACGAAGGCGAGG
GCCTCCCACTGGCGGCGCCTTTTGAGCCTTGGGGCCACTCCGGAGGAGCCTCTGTTGGACTTCAAGATACCAGATGACAATTTTAGCATC
CCAGAAGGTGAAGAAGATCTGGCAAAAGCAATTCAGATGGCCCAAGAACAGGCTACAGATACTGAAATTTTGGAAATTCAGCAAGAGACA
GATATCCCTGAAAGAGAGCTTGTTAGAGCCCTACAGTCCCTCGCCTGTGGTAAACCAACACAGCGGGTTCTTACAAAAGAACCCAAATCA
AAGGAAATAGAAAATGGTCATATATTTACAGTTAATGATCAATTCACATCCAAACTACACAGAGTCAAGATTCAAACAGTTGCTGCCAAA
CAAGGTGAATCCGACCCAGAGAGGAAAGAAACAAGGCAGAAAGTAGACGACGACAGAAAACATGAGATAGAAGCTGCTATAGTGCGGATA
ATGAAATCTAGAAAGAAGATGCAGCACAATGTTCTAGTAGCGGAGGTAACTCAGCAGTTGAAGGCGCGATTCTTACCAAGTCCAGTTGTT
ATTAAGAAACGTATTGAAGGACTTATTGAGAGAGAATATTTGGCACGAACACCTGAGGATCGCAAAGTATACACATATGTAGCATAAAAT
GCGTTCAGAAATTTGATTTATTCTTGGACTGTACTCTTCGCATGGACTGGGAAGTTCTTTTAAATCATTAAATATTAAGACGACCATCTC
TTCTATTAAATTACAGTACATGTTCTAGACCATTGAGATCAAGCCTTTACTCCCTTTGAGAGTTTCCAACATCAGTTGATTGAGCTTCAG
GCTTTACAACGTTTATCCCTGTAGAGATCATCTTTACAGTTCCTCGGGAAAATGTGAATGTGCTGCGTTTTGTTTTCTTTACTGTATGAA

>85419_85419_12_SPAG16-CUL3_SPAG16_chr2_214162081_ENST00000413312_CUL3_chr2_225346795_ENST00000409777_length(amino acids)=238AA_BP=84
MRAPTTWNVSFPWRRGPLRWRVMGVGTKARASHWRRLLSLGATPEEPLLDFKIPDDNFSIPEGEEDLAKAIQMAQEQATDTEILEIQQET
DIPERELVRALQSLACGKPTQRVLTKEPKSKEIENGHIFTVNDQFTSKLHRVKIQTVAAKQGESDPERKETRQKVDDDRKHEIEAAIVRI

--------------------------------------------------------------
>85419_85419_13_SPAG16-CUL3_SPAG16_chr2_214162081_ENST00000432529_CUL3_chr2_225346795_ENST00000264414_length(transcript)=4931nt_BP=371nt
GAGAGCTCCCGGGGGCCGTTGGGTAGCGTCTTCGCTGTTGCCCTTAGGGACGGCTGTGGGCCTGCTGGGGGTGGGGGCCCGAAGCGCCAG
AGATGGCTGCTCAGCGAGGGATGCCCAGCTCCGCCGTGAGGGTCCTGGAAGAGGCGTTGGGCATGGGTTTGACGGCAGCCGGGGACGCGA
GGGACACGGCGGACGCGGTGGCGGCTGAGGGCGCCTACTACCTGGAACAGGTCACCATAACTGAAGCATCTGAAGATGACTATGAATATG
AAGAGATACCAGATGACAATTTTAGCATCCCAGAAGGTGAAGAAGATCTGGCAAAAGCAATTCAGATGGCCCAAGAACAGGCTACAGATA
CTGAAATTTTGGAAATTCAGCAAGAGACAGATATCCCTGAAAGAGAGCTTGTTAGAGCCCTACAGTCCCTCGCCTGTGGTAAACCAACAC
AGCGGGTTCTTACAAAAGAACCCAAATCAAAGGAAATAGAAAATGGTCATATATTTACAGTTAATGATCAATTCACATCCAAACTACACA
GAGTCAAGATTCAAACAGTTGCTGCCAAACAAGGTGAATCCGACCCAGAGAGGAAAGAAACAAGGCAGAAAGTAGACGACGACAGAAAAC
ATGAGATAGAAGCTGCTATAGTGCGGATAATGAAATCTAGAAAGAAGATGCAGCACAATGTTCTAGTAGCGGAGGTAACTCAGCAGTTGA
AGGCGCGATTCTTACCAAGTCCAGTTGTTATTAAGAAACGTATTGAAGGACTTATTGAGAGAGAATATTTGGCACGAACACCTGAGGATC
GCAAAGTATACACATATGTAGCATAAAATGCGTTCAGAAATTTGATTTATTCTTGGACTGTACTCTTCGCATGGACTGGGAAGTTCTTTT
AAATCATTAAATATTAAGACGACCATCTCTTCTATTAAATTACAGTACATGTTCTAGACCATTGAGATCAAGCCTTTACTCCCTTTGAGA
GTTTCCAACATCAGTTGATTGAGCTTCAGGCTTTACAACGTTTATCCCTGTAGAGATCATCTTTACAGTTCCTCGGGAAAATGTGAATGT
GCTGCGTTTTGTTTTCTTTACTGTATGAAAACAGGAAAATAAAAGAGAAATTTAGAAAATACAGCTCATTACAATAAAATTGTTGGATTT
CATTTCCCCAGGTCTTCAGTGTTGATGTAAATGTGTTTTGTAGTGTTGCTTAGCACTTTGCGCATTGTGTAAGTTGGGTAACAAAAATGG
CAAAAGAAATGCAGATTTCCCAGTTATCTTGCTCTGAAGACATTTCTTTAGCTAGTCTTATTTAATTTTAAAGGTTTGATAAATATACAA
AGACCCAAGCATACAATTTGAGCATGCTGTATTCTACCACTTGCACTTACTCATCTTCTAGCCTTATGACCAGGAACCTTTGTTTTGGGC
TCAAGTACACATCCTGATTTGGTTTCTCCCTGTTGTAATTTGAGATTTCCCAAATTAAGTCTTATAATGATTAGGTTTTGTTCTGAGTTA
TTTCTAGAGAAAGAAAGTATTTTAGTATGTGTAAATTGTACAATAATTTTTTTGCTGTTGTACTCACTGCTAATAGTGGATTGTATAGGG
TGGTGTTTTTATTTCATTTATTGTAGACAAAAATAATGAATTTAGTATACACATACCCACTAATTCAAGTATGTCAGAGCACAAAGTTGG
CAGCTGGTTATATTTAATTCAGCCCCTCTGAAAAGCACATACAGTCTATACTTTGTTTATAAATACCCTAGGTCCTCCCTGCCCCTAAAT
ATATATTTTGGTGAAGCTGTGGTGCACTATTAATTTTCTGTTTCAAAATGCAATCTAAAGATGCAATAAATATGATGACCTTGATAGTTT
TAATGAAATCTTCAATTCTTGCAGCTGTGTTTTGGAAAGTGATTAAGCAATATTTCTCAAACCTGATGATTCTTGGATATTTAGCTATTG
TCCTCCAAAGAGTCATCGTTTCACGTTTTCAAACATGTGCTTTGTGCTGAAGATTCTTGTCAGATATCCTGTGCTTCCAGAGTATTTTTA
TCTTCAATTTTATTTAATTTTGTTTCATTTTGTTTTCATAAGACAATGTTTCAGATATGTAATGGGGCAAACCACTATAGATTTCTGTTG
GATAGAAAAATGAAATGTTACTAATAAGTTTAAATTGACCCTTCGTTGACTATCAGTACTGTTGATACATTTATTAGAATGTATGTCTCA
GAAGATGGTTTCTGTTTAAATTTATGGTCAAGTTACAACAACTGAATTCTAATATGGATTAAAAACTCCACATAAATATTTTTCCCCATG
CGTCTTGGGTTATAATTTTCCTTTTAGACTTGCAAATATGCTTTTATTGCAATTTTGTCTCCATCTGTACTGTAGAATTACAAGCCTTGT
GCTCTTTATCTCTACATTTTCCACTTCTACATGATGCAATTAAGATGCCAATGAAAAGTATTGTGAACATTATTCTCAGGACACTTTTAC
CATACTTGAGTAGTACTAAGTCAGGTGTAACATGGAAAGCTAAGGGTTTCACCTTCTGATTTTGACATAATTGGAAATTTTCTATAATGG
TAAGATGTTTATAGGAAAGTAATGGTAGTTCATGTTTGAGAATTTTTTTATTGCTTTCATTTCCCAGTTAAATGATATTTAACACCTGGG
AAAACAGGACAGCTCAGATTGTCGAGTTAGTAAACATGAGCGATGTAAAAACTTTATTTGAAATCTCCTAAGTGAGACATTAAACATTTT
AGTGCTAGTTTAAGCCATTAAAAGTAAAGTTTAAGTTTACGTCATTGTCTCAAGTGTGGCTGTAAAAATCAGATCTAGAGTTTAGAGACA
TACTTGTTAACTTTGGAGCACAGGTTTGATATTTATGCTTCTAAATACATTAAAACATTTCTGAATTGCAGTTGAATGGTTGGAGATTGC
TGGCGATGTGATGCTGCACTGAAAAAACTGGTCACACAAAATGTTTATATGTTTGACTGCATAAGTATTATTTTAGGTCATAAAGGTTAT
AACAAAATACATTTAACATTGCTTTCTTTTTAGCAAGAGGTCACAGATGCTATTTTTTCTCAGTTTTTAATGCTTTAATTTGAAAGAAAA
ATGCATCCTAACCATTCCATCCTGTTGGTGCAGAGAAATTTTGGTGATTTATTAGAAGACTTTTAAGGAGGGTGGATACATAGTTTTTCA
ACTGCAAAAATCATGTCATCTCTTCAGTAACTGTTAAAGTGTAATTCTCTGCCTTCATTATCAAGTCCAGGACAGTGTTTATTTTGAATC
GTTAACATTATTTAAAGACTGAAAATTCATTGCAATTAGGGAACGCACAGCCTCACAAAAAGTGGTTGTGATTGCAAGGATTCTTTATGT
CAGTGAACTTAAAAAGGGAATGGGGGAAGAGATGCATGCCTTTCTAAAGGTATGCTAGAGTCACCTGTGTAGCATTGTAATTATGTACTA
TCAAACCCCCAAGATGCTGATGATAGGCCTTCTCTGTAAGAATCCTTCTCATAGTGAAGCACTGTTGATGTTTTGTTCACCGGATATGTT
GGGTAGCAGAAAAGGCCTAGAACCAGTTTTAAGATTATGCCTACATCTCTAGAAGACTAGTACACTGGCATCATCTTAGGTTTCTAAATA
TTATTTAATTCCTTAATTTGGAAAGCAGTTTTAATGTTTACAGTTTAAGATACTCATTTTCAGTAACTAGTGTTAAAGATTTTTATCTTT
GCCTGTCTACTGTAACTTAAGACTTTCATAGAATAATTTTTTATAGAGTATATGGTATATTGTGTCAATCTTGGAAGGAAAGCTGTTGCA
TATCAATTGTAGGTCATGTATTTTACTATATGTTGCATAGTATTTTGCATTCTGTAAATACGAATGTTAAAACATTTCAGGTCAGCAAAA
TTAGAAGTCATTTCTAGTCCTCAAAGCAGAAATAATTAGAAATGTTAACATTTAAGTGCTTATCATATGCCAGATACTATTCTGAATATT
TTATGTATATTCATTCATTTAGTTGTCATATTGGCTTTATGTGACATAACTGTCATTATACCAGTGTTGTCCAAGGTTGCTAGCAGGAAA
TGGCAGAGCCAGGAGTTGGACCTAGGTTTAATCCTATCCATATTCCATGTTACAAATTGACATGATTTTCCATATTAAAAAATTTTCATT
TATTTTGTACCTCATTCACATGAATAGTAATGTGACAAACTAAAGTTAATACATGAAGCATTGCAATATGGAATTTTGCACATTTTTGTT
AGCTTTACATTATTTGCTGATACCAACTTTTGGTAGGAAGGAAAACAGGGAAGGTGATTGCTGCTATTCTGGAATGTGTCCATTGAAAAG
AAAATAGGCGCTTTGTCTCCTACAATCTTAGAGAAAGTTTTACATACTTAAGTGGGTACCACAGATAGGCATGTACCTTAAATTCAAATC
TACAGTTTTACAAAATGTTTTCCTTTGTGTGCCTTTCCTATGTCAAATTAGCCAGAAGGAAGAAGAGACGTTAAGAATGGCAGATAAATT
TAACAGGTAATGATACAGAGATTGGCCATTACGCCAGCTCTCAGGAGAAAAACAACTAGGATGTCTTGAAACCCGTGCATTTAATTTTAG
AAATGGCAAATTTGTAAGCGTGTCATTTAAGTAATTTGATGCTCAGTTTTAGGGTCTAAGTTGACCTCGAGTGAGCCATGCAAAAATAGC
TTTAAAATTATACATGAGCAGCTCAAAGTAAACGTGTATTTTTTAGTAACAATGAAATTGTCAAATTTCAAGATTTTAATAACAGGACAG

>85419_85419_13_SPAG16-CUL3_SPAG16_chr2_214162081_ENST00000432529_CUL3_chr2_225346795_ENST00000264414_length(amino acids)=260AA_BP=106
MWACWGWGPEAPEMAAQRGMPSSAVRVLEEALGMGLTAAGDARDTADAVAAEGAYYLEQVTITEASEDDYEYEEIPDDNFSIPEGEEDLA
KAIQMAQEQATDTEILEIQQETDIPERELVRALQSLACGKPTQRVLTKEPKSKEIENGHIFTVNDQFTSKLHRVKIQTVAAKQGESDPER

--------------------------------------------------------------
>85419_85419_14_SPAG16-CUL3_SPAG16_chr2_214162081_ENST00000432529_CUL3_chr2_225346795_ENST00000344951_length(transcript)=4929nt_BP=371nt
GAGAGCTCCCGGGGGCCGTTGGGTAGCGTCTTCGCTGTTGCCCTTAGGGACGGCTGTGGGCCTGCTGGGGGTGGGGGCCCGAAGCGCCAG
AGATGGCTGCTCAGCGAGGGATGCCCAGCTCCGCCGTGAGGGTCCTGGAAGAGGCGTTGGGCATGGGTTTGACGGCAGCCGGGGACGCGA
GGGACACGGCGGACGCGGTGGCGGCTGAGGGCGCCTACTACCTGGAACAGGTCACCATAACTGAAGCATCTGAAGATGACTATGAATATG
AAGAGATACCAGATGACAATTTTAGCATCCCAGAAGGTGAAGAAGATCTGGCAAAAGCAATTCAGATGGCCCAAGAACAGGCTACAGATA
CTGAAATTTTGGAAATTCAGCAAGAGACAGATATCCCTGAAAGAGAGCTTGTTAGAGCCCTACAGTCCCTCGCCTGTGGTAAACCAACAC
AGCGGGTTCTTACAAAAGAACCCAAATCAAAGGAAATAGAAAATGGTCATATATTTACAGTTAATGATCAATTCACATCCAAACTACACA
GAGTCAAGATTCAAACAGTTGCTGCCAAACAAGGTGAATCCGACCCAGAGAGGAAAGAAACAAGGCAGAAAGTAGACGACGACAGAAAAC
ATGAGATAGAAGCTGCTATAGTGCGGATAATGAAATCTAGAAAGAAGATGCAGCACAATGTTCTAGTAGCGGAGGTAACTCAGCAGTTGA
AGGCGCGATTCTTACCAAGTCCAGTTGTTATTAAGAAACGTATTGAAGGACTTATTGAGAGAGAATATTTGGCACGAACACCTGAGGATC
GCAAAGTATACACATATGTAGCATAAAATGCGTTCAGAAATTTGATTTATTCTTGGACTGTACTCTTCGCATGGACTGGGAAGTTCTTTT
AAATCATTAAATATTAAGACGACCATCTCTTCTATTAAATTACAGTACATGTTCTAGACCATTGAGATCAAGCCTTTACTCCCTTTGAGA
GTTTCCAACATCAGTTGATTGAGCTTCAGGCTTTACAACGTTTATCCCTGTAGAGATCATCTTTACAGTTCCTCGGGAAAATGTGAATGT
GCTGCGTTTTGTTTTCTTTACTGTATGAAAACAGGAAAATAAAAGAGAAATTTAGAAAATACAGCTCATTACAATAAAATTGTTGGATTT
CATTTCCCCAGGTCTTCAGTGTTGATGTAAATGTGTTTTGTAGTGTTGCTTAGCACTTTGCGCATTGTGTAAGTTGGGTAACAAAAATGG
CAAAAGAAATGCAGATTTCCCAGTTATCTTGCTCTGAAGACATTTCTTTAGCTAGTCTTATTTAATTTTAAAGGTTTGATAAATATACAA
AGACCCAAGCATACAATTTGAGCATGCTGTATTCTACCACTTGCACTTACTCATCTTCTAGCCTTATGACCAGGAACCTTTGTTTTGGGC
TCAAGTACACATCCTGATTTGGTTTCTCCCTGTTGTAATTTGAGATTTCCCAAATTAAGTCTTATAATGATTAGGTTTTGTTCTGAGTTA
TTTCTAGAGAAAGAAAGTATTTTAGTATGTGTAAATTGTACAATAATTTTTTTGCTGTTGTACTCACTGCTAATAGTGGATTGTATAGGG
TGGTGTTTTTATTTCATTTATTGTAGACAAAAATAATGAATTTAGTATACACATACCCACTAATTCAAGTATGTCAGAGCACAAAGTTGG
CAGCTGGTTATATTTAATTCAGCCCCTCTGAAAAGCACATACAGTCTATACTTTGTTTATAAATACCCTAGGTCCTCCCTGCCCCTAAAT
ATATATTTTGGTGAAGCTGTGGTGCACTATTAATTTTCTGTTTCAAAATGCAATCTAAAGATGCAATAAATATGATGACCTTGATAGTTT
TAATGAAATCTTCAATTCTTGCAGCTGTGTTTTGGAAAGTGATTAAGCAATATTTCTCAAACCTGATGATTCTTGGATATTTAGCTATTG
TCCTCCAAAGAGTCATCGTTTCACGTTTTCAAACATGTGCTTTGTGCTGAAGATTCTTGTCAGATATCCTGTGCTTCCAGAGTATTTTTA
TCTTCAATTTTATTTAATTTTGTTTCATTTTGTTTTCATAAGACAATGTTTCAGATATGTAATGGGGCAAACCACTATAGATTTCTGTTG
GATAGAAAAATGAAATGTTACTAATAAGTTTAAATTGACCCTTCGTTGACTATCAGTACTGTTGATACATTTATTAGAATGTATGTCTCA
GAAGATGGTTTCTGTTTAAATTTATGGTCAAGTTACAACAACTGAATTCTAATATGGATTAAAAACTCCACATAAATATTTTTCCCCATG
CGTCTTGGGTTATAATTTTCCTTTTAGACTTGCAAATATGCTTTTATTGCAATTTTGTCTCCATCTGTACTGTAGAATTACAAGCCTTGT
GCTCTTTATCTCTACATTTTCCACTTCTACATGATGCAATTAAGATGCCAATGAAAAGTATTGTGAACATTATTCTCAGGACACTTTTAC
CATACTTGAGTAGTACTAAGTCAGGTGTAACATGGAAAGCTAAGGGTTTCACCTTCTGATTTTGACATAATTGGAAATTTTCTATAATGG
TAAGATGTTTATAGGAAAGTAATGGTAGTTCATGTTTGAGAATTTTTTTATTGCTTTCATTTCCCAGTTAAATGATATTTAACACCTGGG
AAAACAGGACAGCTCAGATTGTCGAGTTAGTAAACATGAGCGATGTAAAAACTTTATTTGAAATCTCCTAAGTGAGACATTAAACATTTT
AGTGCTAGTTTAAGCCATTAAAAGTAAAGTTTAAGTTTACGTCATTGTCTCAAGTGTGGCTGTAAAAATCAGATCTAGAGTTTAGAGACA
TACTTGTTAACTTTGGAGCACAGGTTTGATATTTATGCTTCTAAATACATTAAAACATTTCTGAATTGCAGTTGAATGGTTGGAGATTGC
TGGCGATGTGATGCTGCACTGAAAAAACTGGTCACACAAAATGTTTATATGTTTGACTGCATAAGTATTATTTTAGGTCATAAAGGTTAT
AACAAAATACATTTAACATTGCTTTCTTTTTAGCAAGAGGTCACAGATGCTATTTTTTCTCAGTTTTTAATGCTTTAATTTGAAAGAAAA
ATGCATCCTAACCATTCCATCCTGTTGGTGCAGAGAAATTTTGGTGATTTATTAGAAGACTTTTAAGGAGGGTGGATACATAGTTTTTCA
ACTGCAAAAATCATGTCATCTCTTCAGTAACTGTTAAAGTGTAATTCTCTGCCTTCATTATCAAGTCCAGGACAGTGTTTATTTTGAATC
GTTAACATTATTTAAAGACTGAAAATTCATTGCAATTAGGGAACGCACAGCCTCACAAAAAGTGGTTGTGATTGCAAGGATTCTTTATGT
CAGTGAACTTAAAAAGGGAATGGGGGAAGAGATGCATGCCTTTCTAAAGGTATGCTAGAGTCACCTGTGTAGCATTGTAATTATGTACTA
TCAAACCCCCAAGATGCTGATGATAGGCCTTCTCTGTAAGAATCCTTCTCATAGTGAAGCACTGTTGATGTTTTGTTCACCGGATATGTT
GGGTAGCAGAAAAGGCCTAGAACCAGTTTTAAGATTATGCCTACATCTCTAGAAGACTAGTACACTGGCATCATCTTAGGTTTCTAAATA
TTATTTAATTCCTTAATTTGGAAAGCAGTTTTAATGTTTACAGTTTAAGATACTCATTTTCAGTAACTAGTGTTAAAGATTTTTATCTTT
GCCTGTCTACTGTAACTTAAGACTTTCATAGAATAATTTTTTATAGAGTATATGGTATATTGTGTCAATCTTGGAAGGAAAGCTGTTGCA
TATCAATTGTAGGTCATGTATTTTACTATATGTTGCATAGTATTTTGCATTCTGTAAATACGAATGTTAAAACATTTCAGGTCAGCAAAA
TTAGAAGTCATTTCTAGTCCTCAAAGCAGAAATAATTAGAAATGTTAACATTTAAGTGCTTATCATATGCCAGATACTATTCTGAATATT
TTATGTATATTCATTCATTTAGTTGTCATATTGGCTTTATGTGACATAACTGTCATTATACCAGTGTTGTCCAAGGTTGCTAGCAGGAAA
TGGCAGAGCCAGGAGTTGGACCTAGGTTTAATCCTATCCATATTCCATGTTACAAATTGACATGATTTTCCATATTAAAAAATTTTCATT
TATTTTGTACCTCATTCACATGAATAGTAATGTGACAAACTAAAGTTAATACATGAAGCATTGCAATATGGAATTTTGCACATTTTTGTT
AGCTTTACATTATTTGCTGATACCAACTTTTGGTAGGAAGGAAAACAGGGAAGGTGATTGCTGCTATTCTGGAATGTGTCCATTGAAAAG
AAAATAGGCGCTTTGTCTCCTACAATCTTAGAGAAAGTTTTACATACTTAAGTGGGTACCACAGATAGGCATGTACCTTAAATTCAAATC
TACAGTTTTACAAAATGTTTTCCTTTGTGTGCCTTTCCTATGTCAAATTAGCCAGAAGGAAGAAGAGACGTTAAGAATGGCAGATAAATT
TAACAGGTAATGATACAGAGATTGGCCATTACGCCAGCTCTCAGGAGAAAAACAACTAGGATGTCTTGAAACCCGTGCATTTAATTTTAG
AAATGGCAAATTTGTAAGCGTGTCATTTAAGTAATTTGATGCTCAGTTTTAGGGTCTAAGTTGACCTCGAGTGAGCCATGCAAAAATAGC
TTTAAAATTATACATGAGCAGCTCAAAGTAAACGTGTATTTTTTAGTAACAATGAAATTGTCAAATTTCAAGATTTTAATAACAGGACAG

>85419_85419_14_SPAG16-CUL3_SPAG16_chr2_214162081_ENST00000432529_CUL3_chr2_225346795_ENST00000344951_length(amino acids)=260AA_BP=106
MWACWGWGPEAPEMAAQRGMPSSAVRVLEEALGMGLTAAGDARDTADAVAAEGAYYLEQVTITEASEDDYEYEEIPDDNFSIPEGEEDLA
KAIQMAQEQATDTEILEIQQETDIPERELVRALQSLACGKPTQRVLTKEPKSKEIENGHIFTVNDQFTSKLHRVKIQTVAAKQGESDPER

--------------------------------------------------------------
>85419_85419_15_SPAG16-CUL3_SPAG16_chr2_214162081_ENST00000432529_CUL3_chr2_225346795_ENST00000409096_length(transcript)=1159nt_BP=371nt
GAGAGCTCCCGGGGGCCGTTGGGTAGCGTCTTCGCTGTTGCCCTTAGGGACGGCTGTGGGCCTGCTGGGGGTGGGGGCCCGAAGCGCCAG
AGATGGCTGCTCAGCGAGGGATGCCCAGCTCCGCCGTGAGGGTCCTGGAAGAGGCGTTGGGCATGGGTTTGACGGCAGCCGGGGACGCGA
GGGACACGGCGGACGCGGTGGCGGCTGAGGGCGCCTACTACCTGGAACAGGTCACCATAACTGAAGCATCTGAAGATGACTATGAATATG
AAGAGATACCAGATGACAATTTTAGCATCCCAGAAGGTGAAGAAGATCTGGCAAAAGCAATTCAGATGGCCCAAGAACAGGCTACAGATA
CTGAAATTTTGGAAATTCAGCAAGAGACAGATATCCCTGAAAGAGAGCTTGTTAGAGCCCTACAGTCCCTCGCCTGTGGTAAACCAACAC
AGCGGGTTCTTACAAAAGAACCCAAATCAAAGGAAATAGAAAATGGTCATATATTTACAGTTAATGATCAATTCACATCCAAACTACACA
GAGTCAAGATTCAAACAGTTGCTGCCAAACAAGGTGAATCCGACCCAGAGAGGAAAGAAACAAGGCAGAAAGTAGACGACGACAGAAAAC
ATGAGATAGAAGCTGCTATAGTGCGGATAATGAAATCTAGAAAGAAGATGCAGCACAATGTTCTAGTAGCGGAGGTAACTCAGCAGTTGA
AGGCGCGATTCTTACCAAGTCCAGTTGTTATTAAGAAACGTATTGAAGGACTTATTGAGAGAGAATATTTGGCACGAACACCTGAGGATC
GCAAAGTATACACATATGTAGCATAAAATGCGTTCAGAAATTTGATTTATTCTTGGACTGTACTCTTCGCATGGACTGGGAAGTTCTTTT
AAATCATTAAATATTAAGACGACCATCTCTTCTATTAAATTACAGTACATGTTCTAGACCATTGAGATCAAGCCTTTACTCCCTTTGAGA
GTTTCCAACATCAGTTGATTGAGCTTCAGGCTTTACAACGTTTATCCCTGTAGAGATCATCTTTACAGTTCCTCGGGAAAATGTGAATGT

>85419_85419_15_SPAG16-CUL3_SPAG16_chr2_214162081_ENST00000432529_CUL3_chr2_225346795_ENST00000409096_length(amino acids)=260AA_BP=106
MWACWGWGPEAPEMAAQRGMPSSAVRVLEEALGMGLTAAGDARDTADAVAAEGAYYLEQVTITEASEDDYEYEEIPDDNFSIPEGEEDLA
KAIQMAQEQATDTEILEIQQETDIPERELVRALQSLACGKPTQRVLTKEPKSKEIENGHIFTVNDQFTSKLHRVKIQTVAAKQGESDPER

--------------------------------------------------------------
>85419_85419_16_SPAG16-CUL3_SPAG16_chr2_214162081_ENST00000432529_CUL3_chr2_225346795_ENST00000409777_length(transcript)=1142nt_BP=371nt
GAGAGCTCCCGGGGGCCGTTGGGTAGCGTCTTCGCTGTTGCCCTTAGGGACGGCTGTGGGCCTGCTGGGGGTGGGGGCCCGAAGCGCCAG
AGATGGCTGCTCAGCGAGGGATGCCCAGCTCCGCCGTGAGGGTCCTGGAAGAGGCGTTGGGCATGGGTTTGACGGCAGCCGGGGACGCGA
GGGACACGGCGGACGCGGTGGCGGCTGAGGGCGCCTACTACCTGGAACAGGTCACCATAACTGAAGCATCTGAAGATGACTATGAATATG
AAGAGATACCAGATGACAATTTTAGCATCCCAGAAGGTGAAGAAGATCTGGCAAAAGCAATTCAGATGGCCCAAGAACAGGCTACAGATA
CTGAAATTTTGGAAATTCAGCAAGAGACAGATATCCCTGAAAGAGAGCTTGTTAGAGCCCTACAGTCCCTCGCCTGTGGTAAACCAACAC
AGCGGGTTCTTACAAAAGAACCCAAATCAAAGGAAATAGAAAATGGTCATATATTTACAGTTAATGATCAATTCACATCCAAACTACACA
GAGTCAAGATTCAAACAGTTGCTGCCAAACAAGGTGAATCCGACCCAGAGAGGAAAGAAACAAGGCAGAAAGTAGACGACGACAGAAAAC
ATGAGATAGAAGCTGCTATAGTGCGGATAATGAAATCTAGAAAGAAGATGCAGCACAATGTTCTAGTAGCGGAGGTAACTCAGCAGTTGA
AGGCGCGATTCTTACCAAGTCCAGTTGTTATTAAGAAACGTATTGAAGGACTTATTGAGAGAGAATATTTGGCACGAACACCTGAGGATC
GCAAAGTATACACATATGTAGCATAAAATGCGTTCAGAAATTTGATTTATTCTTGGACTGTACTCTTCGCATGGACTGGGAAGTTCTTTT
AAATCATTAAATATTAAGACGACCATCTCTTCTATTAAATTACAGTACATGTTCTAGACCATTGAGATCAAGCCTTTACTCCCTTTGAGA
GTTTCCAACATCAGTTGATTGAGCTTCAGGCTTTACAACGTTTATCCCTGTAGAGATCATCTTTACAGTTCCTCGGGAAAATGTGAATGT

>85419_85419_16_SPAG16-CUL3_SPAG16_chr2_214162081_ENST00000432529_CUL3_chr2_225346795_ENST00000409777_length(amino acids)=260AA_BP=106
MWACWGWGPEAPEMAAQRGMPSSAVRVLEEALGMGLTAAGDARDTADAVAAEGAYYLEQVTITEASEDDYEYEEIPDDNFSIPEGEEDLA
KAIQMAQEQATDTEILEIQQETDIPERELVRALQSLACGKPTQRVLTKEPKSKEIENGHIFTVNDQFTSKLHRVKIQTVAAKQGESDPER

--------------------------------------------------------------
>85419_85419_17_SPAG16-CUL3_SPAG16_chr2_214162081_ENST00000447990_CUL3_chr2_225346795_ENST00000264414_length(transcript)=4842nt_BP=282nt
GAGATGGCTGCTCAGCGAGGGATGCCCAGCTCCGCCGTGAGGGTCCTGGAAGAGGCGTTGGGCATGGGTTTGACGGCAGCCGGGGACGCG
AGGGACACGGCGGACGCGGTGGCGGCTGAGGGCGCCTACTACCTGGAACAGGTCACCATAACTGAAGCATCTGAAGATGACTATGAATAT
GAAGAGATACCAGATGACAATTTTAGCATCCCAGAAGGTGAAGAAGATCTGGCAAAAGCAATTCAGATGGCCCAAGAACAGGCTACAGAT
ACTGAAATTTTGGAAATTCAGCAAGAGACAGATATCCCTGAAAGAGAGCTTGTTAGAGCCCTACAGTCCCTCGCCTGTGGTAAACCAACA
CAGCGGGTTCTTACAAAAGAACCCAAATCAAAGGAAATAGAAAATGGTCATATATTTACAGTTAATGATCAATTCACATCCAAACTACAC
AGAGTCAAGATTCAAACAGTTGCTGCCAAACAAGGTGAATCCGACCCAGAGAGGAAAGAAACAAGGCAGAAAGTAGACGACGACAGAAAA
CATGAGATAGAAGCTGCTATAGTGCGGATAATGAAATCTAGAAAGAAGATGCAGCACAATGTTCTAGTAGCGGAGGTAACTCAGCAGTTG
AAGGCGCGATTCTTACCAAGTCCAGTTGTTATTAAGAAACGTATTGAAGGACTTATTGAGAGAGAATATTTGGCACGAACACCTGAGGAT
CGCAAAGTATACACATATGTAGCATAAAATGCGTTCAGAAATTTGATTTATTCTTGGACTGTACTCTTCGCATGGACTGGGAAGTTCTTT
TAAATCATTAAATATTAAGACGACCATCTCTTCTATTAAATTACAGTACATGTTCTAGACCATTGAGATCAAGCCTTTACTCCCTTTGAG
AGTTTCCAACATCAGTTGATTGAGCTTCAGGCTTTACAACGTTTATCCCTGTAGAGATCATCTTTACAGTTCCTCGGGAAAATGTGAATG
TGCTGCGTTTTGTTTTCTTTACTGTATGAAAACAGGAAAATAAAAGAGAAATTTAGAAAATACAGCTCATTACAATAAAATTGTTGGATT
TCATTTCCCCAGGTCTTCAGTGTTGATGTAAATGTGTTTTGTAGTGTTGCTTAGCACTTTGCGCATTGTGTAAGTTGGGTAACAAAAATG
GCAAAAGAAATGCAGATTTCCCAGTTATCTTGCTCTGAAGACATTTCTTTAGCTAGTCTTATTTAATTTTAAAGGTTTGATAAATATACA
AAGACCCAAGCATACAATTTGAGCATGCTGTATTCTACCACTTGCACTTACTCATCTTCTAGCCTTATGACCAGGAACCTTTGTTTTGGG
CTCAAGTACACATCCTGATTTGGTTTCTCCCTGTTGTAATTTGAGATTTCCCAAATTAAGTCTTATAATGATTAGGTTTTGTTCTGAGTT
ATTTCTAGAGAAAGAAAGTATTTTAGTATGTGTAAATTGTACAATAATTTTTTTGCTGTTGTACTCACTGCTAATAGTGGATTGTATAGG
GTGGTGTTTTTATTTCATTTATTGTAGACAAAAATAATGAATTTAGTATACACATACCCACTAATTCAAGTATGTCAGAGCACAAAGTTG
GCAGCTGGTTATATTTAATTCAGCCCCTCTGAAAAGCACATACAGTCTATACTTTGTTTATAAATACCCTAGGTCCTCCCTGCCCCTAAA
TATATATTTTGGTGAAGCTGTGGTGCACTATTAATTTTCTGTTTCAAAATGCAATCTAAAGATGCAATAAATATGATGACCTTGATAGTT
TTAATGAAATCTTCAATTCTTGCAGCTGTGTTTTGGAAAGTGATTAAGCAATATTTCTCAAACCTGATGATTCTTGGATATTTAGCTATT
GTCCTCCAAAGAGTCATCGTTTCACGTTTTCAAACATGTGCTTTGTGCTGAAGATTCTTGTCAGATATCCTGTGCTTCCAGAGTATTTTT
ATCTTCAATTTTATTTAATTTTGTTTCATTTTGTTTTCATAAGACAATGTTTCAGATATGTAATGGGGCAAACCACTATAGATTTCTGTT
GGATAGAAAAATGAAATGTTACTAATAAGTTTAAATTGACCCTTCGTTGACTATCAGTACTGTTGATACATTTATTAGAATGTATGTCTC
AGAAGATGGTTTCTGTTTAAATTTATGGTCAAGTTACAACAACTGAATTCTAATATGGATTAAAAACTCCACATAAATATTTTTCCCCAT
GCGTCTTGGGTTATAATTTTCCTTTTAGACTTGCAAATATGCTTTTATTGCAATTTTGTCTCCATCTGTACTGTAGAATTACAAGCCTTG
TGCTCTTTATCTCTACATTTTCCACTTCTACATGATGCAATTAAGATGCCAATGAAAAGTATTGTGAACATTATTCTCAGGACACTTTTA
CCATACTTGAGTAGTACTAAGTCAGGTGTAACATGGAAAGCTAAGGGTTTCACCTTCTGATTTTGACATAATTGGAAATTTTCTATAATG
GTAAGATGTTTATAGGAAAGTAATGGTAGTTCATGTTTGAGAATTTTTTTATTGCTTTCATTTCCCAGTTAAATGATATTTAACACCTGG
GAAAACAGGACAGCTCAGATTGTCGAGTTAGTAAACATGAGCGATGTAAAAACTTTATTTGAAATCTCCTAAGTGAGACATTAAACATTT
TAGTGCTAGTTTAAGCCATTAAAAGTAAAGTTTAAGTTTACGTCATTGTCTCAAGTGTGGCTGTAAAAATCAGATCTAGAGTTTAGAGAC
ATACTTGTTAACTTTGGAGCACAGGTTTGATATTTATGCTTCTAAATACATTAAAACATTTCTGAATTGCAGTTGAATGGTTGGAGATTG
CTGGCGATGTGATGCTGCACTGAAAAAACTGGTCACACAAAATGTTTATATGTTTGACTGCATAAGTATTATTTTAGGTCATAAAGGTTA
TAACAAAATACATTTAACATTGCTTTCTTTTTAGCAAGAGGTCACAGATGCTATTTTTTCTCAGTTTTTAATGCTTTAATTTGAAAGAAA
AATGCATCCTAACCATTCCATCCTGTTGGTGCAGAGAAATTTTGGTGATTTATTAGAAGACTTTTAAGGAGGGTGGATACATAGTTTTTC
AACTGCAAAAATCATGTCATCTCTTCAGTAACTGTTAAAGTGTAATTCTCTGCCTTCATTATCAAGTCCAGGACAGTGTTTATTTTGAAT
CGTTAACATTATTTAAAGACTGAAAATTCATTGCAATTAGGGAACGCACAGCCTCACAAAAAGTGGTTGTGATTGCAAGGATTCTTTATG
TCAGTGAACTTAAAAAGGGAATGGGGGAAGAGATGCATGCCTTTCTAAAGGTATGCTAGAGTCACCTGTGTAGCATTGTAATTATGTACT
ATCAAACCCCCAAGATGCTGATGATAGGCCTTCTCTGTAAGAATCCTTCTCATAGTGAAGCACTGTTGATGTTTTGTTCACCGGATATGT
TGGGTAGCAGAAAAGGCCTAGAACCAGTTTTAAGATTATGCCTACATCTCTAGAAGACTAGTACACTGGCATCATCTTAGGTTTCTAAAT
ATTATTTAATTCCTTAATTTGGAAAGCAGTTTTAATGTTTACAGTTTAAGATACTCATTTTCAGTAACTAGTGTTAAAGATTTTTATCTT
TGCCTGTCTACTGTAACTTAAGACTTTCATAGAATAATTTTTTATAGAGTATATGGTATATTGTGTCAATCTTGGAAGGAAAGCTGTTGC
ATATCAATTGTAGGTCATGTATTTTACTATATGTTGCATAGTATTTTGCATTCTGTAAATACGAATGTTAAAACATTTCAGGTCAGCAAA
ATTAGAAGTCATTTCTAGTCCTCAAAGCAGAAATAATTAGAAATGTTAACATTTAAGTGCTTATCATATGCCAGATACTATTCTGAATAT
TTTATGTATATTCATTCATTTAGTTGTCATATTGGCTTTATGTGACATAACTGTCATTATACCAGTGTTGTCCAAGGTTGCTAGCAGGAA
ATGGCAGAGCCAGGAGTTGGACCTAGGTTTAATCCTATCCATATTCCATGTTACAAATTGACATGATTTTCCATATTAAAAAATTTTCAT
TTATTTTGTACCTCATTCACATGAATAGTAATGTGACAAACTAAAGTTAATACATGAAGCATTGCAATATGGAATTTTGCACATTTTTGT
TAGCTTTACATTATTTGCTGATACCAACTTTTGGTAGGAAGGAAAACAGGGAAGGTGATTGCTGCTATTCTGGAATGTGTCCATTGAAAA
GAAAATAGGCGCTTTGTCTCCTACAATCTTAGAGAAAGTTTTACATACTTAAGTGGGTACCACAGATAGGCATGTACCTTAAATTCAAAT
CTACAGTTTTACAAAATGTTTTCCTTTGTGTGCCTTTCCTATGTCAAATTAGCCAGAAGGAAGAAGAGACGTTAAGAATGGCAGATAAAT
TTAACAGGTAATGATACAGAGATTGGCCATTACGCCAGCTCTCAGGAGAAAAACAACTAGGATGTCTTGAAACCCGTGCATTTAATTTTA
GAAATGGCAAATTTGTAAGCGTGTCATTTAAGTAATTTGATGCTCAGTTTTAGGGTCTAAGTTGACCTCGAGTGAGCCATGCAAAAATAG
CTTTAAAATTATACATGAGCAGCTCAAAGTAAACGTGTATTTTTTAGTAACAATGAAATTGTCAAATTTCAAGATTTTAATAACAGGACA

>85419_85419_17_SPAG16-CUL3_SPAG16_chr2_214162081_ENST00000447990_CUL3_chr2_225346795_ENST00000264414_length(amino acids)=247AA_BP=93
MAAQRGMPSSAVRVLEEALGMGLTAAGDARDTADAVAAEGAYYLEQVTITEASEDDYEYEEIPDDNFSIPEGEEDLAKAIQMAQEQATDT
EILEIQQETDIPERELVRALQSLACGKPTQRVLTKEPKSKEIENGHIFTVNDQFTSKLHRVKIQTVAAKQGESDPERKETRQKVDDDRKH

--------------------------------------------------------------
>85419_85419_18_SPAG16-CUL3_SPAG16_chr2_214162081_ENST00000447990_CUL3_chr2_225346795_ENST00000344951_length(transcript)=4840nt_BP=282nt
GAGATGGCTGCTCAGCGAGGGATGCCCAGCTCCGCCGTGAGGGTCCTGGAAGAGGCGTTGGGCATGGGTTTGACGGCAGCCGGGGACGCG
AGGGACACGGCGGACGCGGTGGCGGCTGAGGGCGCCTACTACCTGGAACAGGTCACCATAACTGAAGCATCTGAAGATGACTATGAATAT
GAAGAGATACCAGATGACAATTTTAGCATCCCAGAAGGTGAAGAAGATCTGGCAAAAGCAATTCAGATGGCCCAAGAACAGGCTACAGAT
ACTGAAATTTTGGAAATTCAGCAAGAGACAGATATCCCTGAAAGAGAGCTTGTTAGAGCCCTACAGTCCCTCGCCTGTGGTAAACCAACA
CAGCGGGTTCTTACAAAAGAACCCAAATCAAAGGAAATAGAAAATGGTCATATATTTACAGTTAATGATCAATTCACATCCAAACTACAC
AGAGTCAAGATTCAAACAGTTGCTGCCAAACAAGGTGAATCCGACCCAGAGAGGAAAGAAACAAGGCAGAAAGTAGACGACGACAGAAAA
CATGAGATAGAAGCTGCTATAGTGCGGATAATGAAATCTAGAAAGAAGATGCAGCACAATGTTCTAGTAGCGGAGGTAACTCAGCAGTTG
AAGGCGCGATTCTTACCAAGTCCAGTTGTTATTAAGAAACGTATTGAAGGACTTATTGAGAGAGAATATTTGGCACGAACACCTGAGGAT
CGCAAAGTATACACATATGTAGCATAAAATGCGTTCAGAAATTTGATTTATTCTTGGACTGTACTCTTCGCATGGACTGGGAAGTTCTTT
TAAATCATTAAATATTAAGACGACCATCTCTTCTATTAAATTACAGTACATGTTCTAGACCATTGAGATCAAGCCTTTACTCCCTTTGAG
AGTTTCCAACATCAGTTGATTGAGCTTCAGGCTTTACAACGTTTATCCCTGTAGAGATCATCTTTACAGTTCCTCGGGAAAATGTGAATG
TGCTGCGTTTTGTTTTCTTTACTGTATGAAAACAGGAAAATAAAAGAGAAATTTAGAAAATACAGCTCATTACAATAAAATTGTTGGATT
TCATTTCCCCAGGTCTTCAGTGTTGATGTAAATGTGTTTTGTAGTGTTGCTTAGCACTTTGCGCATTGTGTAAGTTGGGTAACAAAAATG
GCAAAAGAAATGCAGATTTCCCAGTTATCTTGCTCTGAAGACATTTCTTTAGCTAGTCTTATTTAATTTTAAAGGTTTGATAAATATACA
AAGACCCAAGCATACAATTTGAGCATGCTGTATTCTACCACTTGCACTTACTCATCTTCTAGCCTTATGACCAGGAACCTTTGTTTTGGG
CTCAAGTACACATCCTGATTTGGTTTCTCCCTGTTGTAATTTGAGATTTCCCAAATTAAGTCTTATAATGATTAGGTTTTGTTCTGAGTT
ATTTCTAGAGAAAGAAAGTATTTTAGTATGTGTAAATTGTACAATAATTTTTTTGCTGTTGTACTCACTGCTAATAGTGGATTGTATAGG
GTGGTGTTTTTATTTCATTTATTGTAGACAAAAATAATGAATTTAGTATACACATACCCACTAATTCAAGTATGTCAGAGCACAAAGTTG
GCAGCTGGTTATATTTAATTCAGCCCCTCTGAAAAGCACATACAGTCTATACTTTGTTTATAAATACCCTAGGTCCTCCCTGCCCCTAAA
TATATATTTTGGTGAAGCTGTGGTGCACTATTAATTTTCTGTTTCAAAATGCAATCTAAAGATGCAATAAATATGATGACCTTGATAGTT
TTAATGAAATCTTCAATTCTTGCAGCTGTGTTTTGGAAAGTGATTAAGCAATATTTCTCAAACCTGATGATTCTTGGATATTTAGCTATT
GTCCTCCAAAGAGTCATCGTTTCACGTTTTCAAACATGTGCTTTGTGCTGAAGATTCTTGTCAGATATCCTGTGCTTCCAGAGTATTTTT
ATCTTCAATTTTATTTAATTTTGTTTCATTTTGTTTTCATAAGACAATGTTTCAGATATGTAATGGGGCAAACCACTATAGATTTCTGTT
GGATAGAAAAATGAAATGTTACTAATAAGTTTAAATTGACCCTTCGTTGACTATCAGTACTGTTGATACATTTATTAGAATGTATGTCTC
AGAAGATGGTTTCTGTTTAAATTTATGGTCAAGTTACAACAACTGAATTCTAATATGGATTAAAAACTCCACATAAATATTTTTCCCCAT
GCGTCTTGGGTTATAATTTTCCTTTTAGACTTGCAAATATGCTTTTATTGCAATTTTGTCTCCATCTGTACTGTAGAATTACAAGCCTTG
TGCTCTTTATCTCTACATTTTCCACTTCTACATGATGCAATTAAGATGCCAATGAAAAGTATTGTGAACATTATTCTCAGGACACTTTTA
CCATACTTGAGTAGTACTAAGTCAGGTGTAACATGGAAAGCTAAGGGTTTCACCTTCTGATTTTGACATAATTGGAAATTTTCTATAATG
GTAAGATGTTTATAGGAAAGTAATGGTAGTTCATGTTTGAGAATTTTTTTATTGCTTTCATTTCCCAGTTAAATGATATTTAACACCTGG
GAAAACAGGACAGCTCAGATTGTCGAGTTAGTAAACATGAGCGATGTAAAAACTTTATTTGAAATCTCCTAAGTGAGACATTAAACATTT
TAGTGCTAGTTTAAGCCATTAAAAGTAAAGTTTAAGTTTACGTCATTGTCTCAAGTGTGGCTGTAAAAATCAGATCTAGAGTTTAGAGAC
ATACTTGTTAACTTTGGAGCACAGGTTTGATATTTATGCTTCTAAATACATTAAAACATTTCTGAATTGCAGTTGAATGGTTGGAGATTG
CTGGCGATGTGATGCTGCACTGAAAAAACTGGTCACACAAAATGTTTATATGTTTGACTGCATAAGTATTATTTTAGGTCATAAAGGTTA
TAACAAAATACATTTAACATTGCTTTCTTTTTAGCAAGAGGTCACAGATGCTATTTTTTCTCAGTTTTTAATGCTTTAATTTGAAAGAAA
AATGCATCCTAACCATTCCATCCTGTTGGTGCAGAGAAATTTTGGTGATTTATTAGAAGACTTTTAAGGAGGGTGGATACATAGTTTTTC
AACTGCAAAAATCATGTCATCTCTTCAGTAACTGTTAAAGTGTAATTCTCTGCCTTCATTATCAAGTCCAGGACAGTGTTTATTTTGAAT
CGTTAACATTATTTAAAGACTGAAAATTCATTGCAATTAGGGAACGCACAGCCTCACAAAAAGTGGTTGTGATTGCAAGGATTCTTTATG
TCAGTGAACTTAAAAAGGGAATGGGGGAAGAGATGCATGCCTTTCTAAAGGTATGCTAGAGTCACCTGTGTAGCATTGTAATTATGTACT
ATCAAACCCCCAAGATGCTGATGATAGGCCTTCTCTGTAAGAATCCTTCTCATAGTGAAGCACTGTTGATGTTTTGTTCACCGGATATGT
TGGGTAGCAGAAAAGGCCTAGAACCAGTTTTAAGATTATGCCTACATCTCTAGAAGACTAGTACACTGGCATCATCTTAGGTTTCTAAAT
ATTATTTAATTCCTTAATTTGGAAAGCAGTTTTAATGTTTACAGTTTAAGATACTCATTTTCAGTAACTAGTGTTAAAGATTTTTATCTT
TGCCTGTCTACTGTAACTTAAGACTTTCATAGAATAATTTTTTATAGAGTATATGGTATATTGTGTCAATCTTGGAAGGAAAGCTGTTGC
ATATCAATTGTAGGTCATGTATTTTACTATATGTTGCATAGTATTTTGCATTCTGTAAATACGAATGTTAAAACATTTCAGGTCAGCAAA
ATTAGAAGTCATTTCTAGTCCTCAAAGCAGAAATAATTAGAAATGTTAACATTTAAGTGCTTATCATATGCCAGATACTATTCTGAATAT
TTTATGTATATTCATTCATTTAGTTGTCATATTGGCTTTATGTGACATAACTGTCATTATACCAGTGTTGTCCAAGGTTGCTAGCAGGAA
ATGGCAGAGCCAGGAGTTGGACCTAGGTTTAATCCTATCCATATTCCATGTTACAAATTGACATGATTTTCCATATTAAAAAATTTTCAT
TTATTTTGTACCTCATTCACATGAATAGTAATGTGACAAACTAAAGTTAATACATGAAGCATTGCAATATGGAATTTTGCACATTTTTGT
TAGCTTTACATTATTTGCTGATACCAACTTTTGGTAGGAAGGAAAACAGGGAAGGTGATTGCTGCTATTCTGGAATGTGTCCATTGAAAA
GAAAATAGGCGCTTTGTCTCCTACAATCTTAGAGAAAGTTTTACATACTTAAGTGGGTACCACAGATAGGCATGTACCTTAAATTCAAAT
CTACAGTTTTACAAAATGTTTTCCTTTGTGTGCCTTTCCTATGTCAAATTAGCCAGAAGGAAGAAGAGACGTTAAGAATGGCAGATAAAT
TTAACAGGTAATGATACAGAGATTGGCCATTACGCCAGCTCTCAGGAGAAAAACAACTAGGATGTCTTGAAACCCGTGCATTTAATTTTA
GAAATGGCAAATTTGTAAGCGTGTCATTTAAGTAATTTGATGCTCAGTTTTAGGGTCTAAGTTGACCTCGAGTGAGCCATGCAAAAATAG
CTTTAAAATTATACATGAGCAGCTCAAAGTAAACGTGTATTTTTTAGTAACAATGAAATTGTCAAATTTCAAGATTTTAATAACAGGACA

>85419_85419_18_SPAG16-CUL3_SPAG16_chr2_214162081_ENST00000447990_CUL3_chr2_225346795_ENST00000344951_length(amino acids)=247AA_BP=93
MAAQRGMPSSAVRVLEEALGMGLTAAGDARDTADAVAAEGAYYLEQVTITEASEDDYEYEEIPDDNFSIPEGEEDLAKAIQMAQEQATDT
EILEIQQETDIPERELVRALQSLACGKPTQRVLTKEPKSKEIENGHIFTVNDQFTSKLHRVKIQTVAAKQGESDPERKETRQKVDDDRKH

--------------------------------------------------------------
>85419_85419_19_SPAG16-CUL3_SPAG16_chr2_214162081_ENST00000447990_CUL3_chr2_225346795_ENST00000409096_length(transcript)=1070nt_BP=282nt
GAGATGGCTGCTCAGCGAGGGATGCCCAGCTCCGCCGTGAGGGTCCTGGAAGAGGCGTTGGGCATGGGTTTGACGGCAGCCGGGGACGCG
AGGGACACGGCGGACGCGGTGGCGGCTGAGGGCGCCTACTACCTGGAACAGGTCACCATAACTGAAGCATCTGAAGATGACTATGAATAT
GAAGAGATACCAGATGACAATTTTAGCATCCCAGAAGGTGAAGAAGATCTGGCAAAAGCAATTCAGATGGCCCAAGAACAGGCTACAGAT
ACTGAAATTTTGGAAATTCAGCAAGAGACAGATATCCCTGAAAGAGAGCTTGTTAGAGCCCTACAGTCCCTCGCCTGTGGTAAACCAACA
CAGCGGGTTCTTACAAAAGAACCCAAATCAAAGGAAATAGAAAATGGTCATATATTTACAGTTAATGATCAATTCACATCCAAACTACAC
AGAGTCAAGATTCAAACAGTTGCTGCCAAACAAGGTGAATCCGACCCAGAGAGGAAAGAAACAAGGCAGAAAGTAGACGACGACAGAAAA
CATGAGATAGAAGCTGCTATAGTGCGGATAATGAAATCTAGAAAGAAGATGCAGCACAATGTTCTAGTAGCGGAGGTAACTCAGCAGTTG
AAGGCGCGATTCTTACCAAGTCCAGTTGTTATTAAGAAACGTATTGAAGGACTTATTGAGAGAGAATATTTGGCACGAACACCTGAGGAT
CGCAAAGTATACACATATGTAGCATAAAATGCGTTCAGAAATTTGATTTATTCTTGGACTGTACTCTTCGCATGGACTGGGAAGTTCTTT
TAAATCATTAAATATTAAGACGACCATCTCTTCTATTAAATTACAGTACATGTTCTAGACCATTGAGATCAAGCCTTTACTCCCTTTGAG
AGTTTCCAACATCAGTTGATTGAGCTTCAGGCTTTACAACGTTTATCCCTGTAGAGATCATCTTTACAGTTCCTCGGGAAAATGTGAATG

>85419_85419_19_SPAG16-CUL3_SPAG16_chr2_214162081_ENST00000447990_CUL3_chr2_225346795_ENST00000409096_length(amino acids)=247AA_BP=93
MAAQRGMPSSAVRVLEEALGMGLTAAGDARDTADAVAAEGAYYLEQVTITEASEDDYEYEEIPDDNFSIPEGEEDLAKAIQMAQEQATDT
EILEIQQETDIPERELVRALQSLACGKPTQRVLTKEPKSKEIENGHIFTVNDQFTSKLHRVKIQTVAAKQGESDPERKETRQKVDDDRKH

--------------------------------------------------------------
>85419_85419_20_SPAG16-CUL3_SPAG16_chr2_214162081_ENST00000447990_CUL3_chr2_225346795_ENST00000409777_length(transcript)=1053nt_BP=282nt
GAGATGGCTGCTCAGCGAGGGATGCCCAGCTCCGCCGTGAGGGTCCTGGAAGAGGCGTTGGGCATGGGTTTGACGGCAGCCGGGGACGCG
AGGGACACGGCGGACGCGGTGGCGGCTGAGGGCGCCTACTACCTGGAACAGGTCACCATAACTGAAGCATCTGAAGATGACTATGAATAT
GAAGAGATACCAGATGACAATTTTAGCATCCCAGAAGGTGAAGAAGATCTGGCAAAAGCAATTCAGATGGCCCAAGAACAGGCTACAGAT
ACTGAAATTTTGGAAATTCAGCAAGAGACAGATATCCCTGAAAGAGAGCTTGTTAGAGCCCTACAGTCCCTCGCCTGTGGTAAACCAACA
CAGCGGGTTCTTACAAAAGAACCCAAATCAAAGGAAATAGAAAATGGTCATATATTTACAGTTAATGATCAATTCACATCCAAACTACAC
AGAGTCAAGATTCAAACAGTTGCTGCCAAACAAGGTGAATCCGACCCAGAGAGGAAAGAAACAAGGCAGAAAGTAGACGACGACAGAAAA
CATGAGATAGAAGCTGCTATAGTGCGGATAATGAAATCTAGAAAGAAGATGCAGCACAATGTTCTAGTAGCGGAGGTAACTCAGCAGTTG
AAGGCGCGATTCTTACCAAGTCCAGTTGTTATTAAGAAACGTATTGAAGGACTTATTGAGAGAGAATATTTGGCACGAACACCTGAGGAT
CGCAAAGTATACACATATGTAGCATAAAATGCGTTCAGAAATTTGATTTATTCTTGGACTGTACTCTTCGCATGGACTGGGAAGTTCTTT
TAAATCATTAAATATTAAGACGACCATCTCTTCTATTAAATTACAGTACATGTTCTAGACCATTGAGATCAAGCCTTTACTCCCTTTGAG
AGTTTCCAACATCAGTTGATTGAGCTTCAGGCTTTACAACGTTTATCCCTGTAGAGATCATCTTTACAGTTCCTCGGGAAAATGTGAATG

>85419_85419_20_SPAG16-CUL3_SPAG16_chr2_214162081_ENST00000447990_CUL3_chr2_225346795_ENST00000409777_length(amino acids)=247AA_BP=93
MAAQRGMPSSAVRVLEEALGMGLTAAGDARDTADAVAAEGAYYLEQVTITEASEDDYEYEEIPDDNFSIPEGEEDLAKAIQMAQEQATDT
EILEIQQETDIPERELVRALQSLACGKPTQRVLTKEPKSKEIENGHIFTVNDQFTSKLHRVKIQTVAAKQGESDPERKETRQKVDDDRKH

--------------------------------------------------------------

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Fusion Gene PPI Analysis for SPAG16-CUL3


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with
TgeneCUL3chr2:214162081chr2:225346795ENST0000026441412162_41614.0769.0KLHL18
TgeneCUL3chr2:214162081chr2:225346795ENST0000034495111152_41548.0703.0KLHL18
TgeneCUL3chr2:214162081chr2:225346795ENST0000040909612162_41590.0745.0KLHL18
TgeneCUL3chr2:214162081chr2:225346795ENST0000040977712162_41590.0745.0KLHL18


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for SPAG16-CUL3


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for SPAG16-CUL3


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource