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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:SPAG9-BRIP1 (FusionGDB2 ID:85454)

Fusion Gene Summary for SPAG9-BRIP1

check button Fusion gene summary
Fusion gene informationFusion gene name: SPAG9-BRIP1
Fusion gene ID: 85454
HgeneTgene
Gene symbol

SPAG9

BRIP1

Gene ID

9043

83990

Gene namesperm associated antigen 9BRCA1 interacting protein C-terminal helicase 1
SynonymsCT89|HLC-6|HLC4|HLC6|JIP-4|JIP4|JLP|PHET|PIG6BACH1|FANCJ|OF
Cytomap

17q21.33

17q23.2

Type of geneprotein-codingprotein-coding
DescriptionC-Jun-amino-terminal kinase-interacting protein 4JNK interacting proteinJNK/SAPK-associated proteinMax-binding proteinc-Jun NH2-terminal kinase-associated leucine zipper proteincancer/testis antigen 89human lung cancer oncogene 6 proteinlung cancerFanconi anemia group J proteinATP-dependent RNA helicase BRIP1BRCA1-associated C-terminal helicase 1BRCA1-binding helicase-like protein BACH1BRCA1/BRCA2-associated helicase 1
Modification date2020031520200315
UniProtAcc.

Q9BX63

Ensembl transtripts involved in fusion geneENST00000262013, ENST00000357122, 
ENST00000505279, ENST00000509724, 
ENST00000510283, 		ENST00000583837, 
ENST00000259008, ENST00000577598, 
Fusion gene scores* DoF score20 X 21 X 10=420012 X 15 X 7=1260
# samples 2513
** MAII scorelog2(25/4200*10)=-4.0703893278914
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(13/1260*10)=-3.27684020535882
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: SPAG9 [Title/Abstract] AND BRIP1 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointBRIP1(59934419)-SPAG9(49157065), # samples:2
SPAG9(49133773)-BRIP1(59924581), # samples:2
Anticipated loss of major functional domain due to fusion event.BRIP1-SPAG9 seems lost the major protein functional domain in Hgene partner, which is a CGC due to the frame-shifted ORF.
BRIP1-SPAG9 seems lost the major protein functional domain in Hgene partner, which is a essential gene due to the frame-shifted ORF.
BRIP1-SPAG9 seems lost the major protein functional domain in Tgene partner, which is a essential gene due to the frame-shifted ORF.
SPAG9-BRIP1 seems lost the major protein functional domain in Hgene partner, which is a essential gene due to the frame-shifted ORF.
SPAG9-BRIP1 seems lost the major protein functional domain in Tgene partner, which is a CGC due to the frame-shifted ORF.
SPAG9-BRIP1 seems lost the major protein functional domain in Tgene partner, which is a essential gene due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneSPAG9

GO:0042147

retrograde transport, endosome to Golgi

19056739

TgeneBRIP1

GO:0006357

regulation of transcription by RNA polymerase II

14504288


check buttonFusion gene breakpoints across SPAG9 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across BRIP1 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4BRCATCGA-AR-A0TQ-01ASPAG9chr17

49133773

-BRIP1chr17

59924581

-
ChimerDB4BRCATCGA-AR-A0TQ-01ASPAG9chr17

49133773

-BRIP1chr17

59926617

-
ChimerDB4BRCATCGA-AR-A0TQSPAG9chr17

49133772

-BRIP1chr17

59924581

-


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Fusion Gene ORF analysis for SPAG9-BRIP1

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000262013ENST00000583837SPAG9chr17

49133773

-BRIP1chr17

59924581

-
5CDS-intronENST00000262013ENST00000583837SPAG9chr17

49133773

-BRIP1chr17

59926617

-
5CDS-intronENST00000262013ENST00000583837SPAG9chr17

49133772

-BRIP1chr17

59924581

-
5CDS-intronENST00000357122ENST00000583837SPAG9chr17

49133773

-BRIP1chr17

59924581

-
5CDS-intronENST00000357122ENST00000583837SPAG9chr17

49133773

-BRIP1chr17

59926617

-
5CDS-intronENST00000357122ENST00000583837SPAG9chr17

49133772

-BRIP1chr17

59924581

-
5CDS-intronENST00000505279ENST00000583837SPAG9chr17

49133773

-BRIP1chr17

59924581

-
5CDS-intronENST00000505279ENST00000583837SPAG9chr17

49133773

-BRIP1chr17

59926617

-
5CDS-intronENST00000505279ENST00000583837SPAG9chr17

49133772

-BRIP1chr17

59924581

-
Frame-shiftENST00000262013ENST00000259008SPAG9chr17

49133773

-BRIP1chr17

59926617

-
Frame-shiftENST00000262013ENST00000577598SPAG9chr17

49133773

-BRIP1chr17

59926617

-
Frame-shiftENST00000357122ENST00000259008SPAG9chr17

49133773

-BRIP1chr17

59926617

-
Frame-shiftENST00000357122ENST00000577598SPAG9chr17

49133773

-BRIP1chr17

59926617

-
Frame-shiftENST00000505279ENST00000259008SPAG9chr17

49133773

-BRIP1chr17

59926617

-
Frame-shiftENST00000505279ENST00000577598SPAG9chr17

49133773

-BRIP1chr17

59926617

-
In-frameENST00000262013ENST00000259008SPAG9chr17

49133773

-BRIP1chr17

59924581

-
In-frameENST00000262013ENST00000259008SPAG9chr17

49133772

-BRIP1chr17

59924581

-
In-frameENST00000262013ENST00000577598SPAG9chr17

49133773

-BRIP1chr17

59924581

-
In-frameENST00000262013ENST00000577598SPAG9chr17

49133772

-BRIP1chr17

59924581

-
In-frameENST00000357122ENST00000259008SPAG9chr17

49133773

-BRIP1chr17

59924581

-
In-frameENST00000357122ENST00000259008SPAG9chr17

49133772

-BRIP1chr17

59924581

-
In-frameENST00000357122ENST00000577598SPAG9chr17

49133773

-BRIP1chr17

59924581

-
In-frameENST00000357122ENST00000577598SPAG9chr17

49133772

-BRIP1chr17

59924581

-
In-frameENST00000505279ENST00000259008SPAG9chr17

49133773

-BRIP1chr17

59924581

-
In-frameENST00000505279ENST00000259008SPAG9chr17

49133772

-BRIP1chr17

59924581

-
In-frameENST00000505279ENST00000577598SPAG9chr17

49133773

-BRIP1chr17

59924581

-
In-frameENST00000505279ENST00000577598SPAG9chr17

49133772

-BRIP1chr17

59924581

-
intron-3CDSENST00000509724ENST00000259008SPAG9chr17

49133773

-BRIP1chr17

59924581

-
intron-3CDSENST00000509724ENST00000259008SPAG9chr17

49133773

-BRIP1chr17

59926617

-
intron-3CDSENST00000509724ENST00000259008SPAG9chr17

49133772

-BRIP1chr17

59924581

-
intron-3CDSENST00000509724ENST00000577598SPAG9chr17

49133773

-BRIP1chr17

59924581

-
intron-3CDSENST00000509724ENST00000577598SPAG9chr17

49133773

-BRIP1chr17

59926617

-
intron-3CDSENST00000509724ENST00000577598SPAG9chr17

49133772

-BRIP1chr17

59924581

-
intron-3CDSENST00000510283ENST00000259008SPAG9chr17

49133773

-BRIP1chr17

59924581

-
intron-3CDSENST00000510283ENST00000259008SPAG9chr17

49133773

-BRIP1chr17

59926617

-
intron-3CDSENST00000510283ENST00000259008SPAG9chr17

49133772

-BRIP1chr17

59924581

-
intron-3CDSENST00000510283ENST00000577598SPAG9chr17

49133773

-BRIP1chr17

59924581

-
intron-3CDSENST00000510283ENST00000577598SPAG9chr17

49133773

-BRIP1chr17

59926617

-
intron-3CDSENST00000510283ENST00000577598SPAG9chr17

49133772

-BRIP1chr17

59924581

-
intron-intronENST00000509724ENST00000583837SPAG9chr17

49133773

-BRIP1chr17

59924581

-
intron-intronENST00000509724ENST00000583837SPAG9chr17

49133773

-BRIP1chr17

59926617

-
intron-intronENST00000509724ENST00000583837SPAG9chr17

49133772

-BRIP1chr17

59924581

-
intron-intronENST00000510283ENST00000583837SPAG9chr17

49133773

-BRIP1chr17

59924581

-
intron-intronENST00000510283ENST00000583837SPAG9chr17

49133773

-BRIP1chr17

59926617

-
intron-intronENST00000510283ENST00000583837SPAG9chr17

49133772

-BRIP1chr17

59924581

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000262013SPAG9chr1749133773-ENST00000259008BRIP1chr1759924581-597770420939461245
ENST00000262013SPAG9chr1749133773-ENST00000577598BRIP1chr1759924581-41667042093181990
ENST00000505279SPAG9chr1749133773-ENST00000259008BRIP1chr1759924581-58465737838151245
ENST00000505279SPAG9chr1749133773-ENST00000577598BRIP1chr1759924581-4035573783050990
ENST00000357122SPAG9chr1749133773-ENST00000259008BRIP1chr1759924581-597770420939461245
ENST00000357122SPAG9chr1749133773-ENST00000577598BRIP1chr1759924581-41667042093181990
ENST00000262013SPAG9chr1749133772-ENST00000259008BRIP1chr1759924581-597770420939461245
ENST00000262013SPAG9chr1749133772-ENST00000577598BRIP1chr1759924581-41667042093181990
ENST00000505279SPAG9chr1749133772-ENST00000259008BRIP1chr1759924581-58465737838151245
ENST00000505279SPAG9chr1749133772-ENST00000577598BRIP1chr1759924581-4035573783050990
ENST00000357122SPAG9chr1749133772-ENST00000259008BRIP1chr1759924581-597770420939461245
ENST00000357122SPAG9chr1749133772-ENST00000577598BRIP1chr1759924581-41667042093181990

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000262013ENST00000259008SPAG9chr1749133773-BRIP1chr1759924581-0.0001051770.99989486
ENST00000262013ENST00000577598SPAG9chr1749133773-BRIP1chr1759924581-0.000210280.9997898
ENST00000505279ENST00000259008SPAG9chr1749133773-BRIP1chr1759924581-9.10E-050.99990904
ENST00000505279ENST00000577598SPAG9chr1749133773-BRIP1chr1759924581-0.0001880470.99981195
ENST00000357122ENST00000259008SPAG9chr1749133773-BRIP1chr1759924581-0.0001051770.99989486
ENST00000357122ENST00000577598SPAG9chr1749133773-BRIP1chr1759924581-0.000210280.9997898
ENST00000262013ENST00000259008SPAG9chr1749133772-BRIP1chr1759924581-0.0001051770.99989486
ENST00000262013ENST00000577598SPAG9chr1749133772-BRIP1chr1759924581-0.000210280.9997898
ENST00000505279ENST00000259008SPAG9chr1749133772-BRIP1chr1759924581-9.10E-050.99990904
ENST00000505279ENST00000577598SPAG9chr1749133772-BRIP1chr1759924581-0.0001880470.99981195
ENST00000357122ENST00000259008SPAG9chr1749133772-BRIP1chr1759924581-0.0001051770.99989486
ENST00000357122ENST00000577598SPAG9chr1749133772-BRIP1chr1759924581-0.000210280.9997898

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Fusion Genomic Features for SPAG9-BRIP1


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for SPAG9-BRIP1


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr17:59934419/chr17:49157065)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
.BRIP1

Q9BX63

FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: DNA-dependent ATPase and 5' to 3' DNA helicase required for the maintenance of chromosomal stability. Acts late in the Fanconi anemia pathway, after FANCD2 ubiquitination. Involved in the repair of DNA double-strand breaks by homologous recombination in a manner that depends on its association with BRCA1. {ECO:0000269|PubMed:11301010, ECO:0000269|PubMed:14983014, ECO:0000269|PubMed:16116421, ECO:0000269|PubMed:16153896}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneSPAG9chr17:49133772chr17:59924581ENST00000262013-33066_1661651322.0Coiled coilOntology_term=ECO:0000255
HgeneSPAG9chr17:49133772chr17:59924581ENST00000357122-32966_1661651308.0Coiled coilOntology_term=ECO:0000255
HgeneSPAG9chr17:49133772chr17:59924581ENST00000505279-33066_1661651312.0Coiled coilOntology_term=ECO:0000255
HgeneSPAG9chr17:49133773chr17:59924581ENST00000262013-33066_1661651322.0Coiled coilOntology_term=ECO:0000255
HgeneSPAG9chr17:49133773chr17:59924581ENST00000357122-32966_1661651308.0Coiled coilOntology_term=ECO:0000255
HgeneSPAG9chr17:49133773chr17:59924581ENST00000505279-33066_1661651312.0Coiled coilOntology_term=ECO:0000255
HgeneSPAG9chr17:49133772chr17:59924581ENST00000262013-3307_951651322.0DomainRH1
HgeneSPAG9chr17:49133772chr17:59924581ENST00000357122-3297_951651308.0DomainRH1
HgeneSPAG9chr17:49133772chr17:59924581ENST00000505279-3307_951651312.0DomainRH1
HgeneSPAG9chr17:49133773chr17:59924581ENST00000262013-3307_951651322.0DomainRH1
HgeneSPAG9chr17:49133773chr17:59924581ENST00000357122-3297_951651308.0DomainRH1
HgeneSPAG9chr17:49133773chr17:59924581ENST00000505279-3307_951651312.0DomainRH1
TgeneBRIP1chr17:49133772chr17:59924581ENST00000259008420393_3961691250.0MotifNote=DEAH box
TgeneBRIP1chr17:49133773chr17:59924581ENST00000259008420393_3961691250.0MotifNote=DEAH box
TgeneBRIP1chr17:49133772chr17:59924581ENST00000259008420185_1921691250.0Nucleotide bindingATP
TgeneBRIP1chr17:49133773chr17:59924581ENST00000259008420185_1921691250.0Nucleotide bindingATP

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneSPAG9chr17:49133772chr17:59924581ENST00000262013-330408_5341651322.0Coiled coilOntology_term=ECO:0000269
HgeneSPAG9chr17:49133772chr17:59924581ENST00000262013-330724_7581651322.0Coiled coilOntology_term=ECO:0000255
HgeneSPAG9chr17:49133772chr17:59924581ENST00000357122-329408_5341651308.0Coiled coilOntology_term=ECO:0000269
HgeneSPAG9chr17:49133772chr17:59924581ENST00000357122-329724_7581651308.0Coiled coilOntology_term=ECO:0000255
HgeneSPAG9chr17:49133772chr17:59924581ENST00000505279-330408_5341651312.0Coiled coilOntology_term=ECO:0000269
HgeneSPAG9chr17:49133772chr17:59924581ENST00000505279-330724_7581651312.0Coiled coilOntology_term=ECO:0000255
HgeneSPAG9chr17:49133772chr17:59924581ENST00000510283-127408_53401178.0Coiled coilOntology_term=ECO:0000269
HgeneSPAG9chr17:49133772chr17:59924581ENST00000510283-12766_16601178.0Coiled coilOntology_term=ECO:0000255
HgeneSPAG9chr17:49133772chr17:59924581ENST00000510283-127724_75801178.0Coiled coilOntology_term=ECO:0000255
HgeneSPAG9chr17:49133773chr17:59924581ENST00000262013-330408_5341651322.0Coiled coilOntology_term=ECO:0000269
HgeneSPAG9chr17:49133773chr17:59924581ENST00000262013-330724_7581651322.0Coiled coilOntology_term=ECO:0000255
HgeneSPAG9chr17:49133773chr17:59924581ENST00000357122-329408_5341651308.0Coiled coilOntology_term=ECO:0000269
HgeneSPAG9chr17:49133773chr17:59924581ENST00000357122-329724_7581651308.0Coiled coilOntology_term=ECO:0000255
HgeneSPAG9chr17:49133773chr17:59924581ENST00000505279-330408_5341651312.0Coiled coilOntology_term=ECO:0000269
HgeneSPAG9chr17:49133773chr17:59924581ENST00000505279-330724_7581651312.0Coiled coilOntology_term=ECO:0000255
HgeneSPAG9chr17:49133773chr17:59924581ENST00000510283-127408_53401178.0Coiled coilOntology_term=ECO:0000269
HgeneSPAG9chr17:49133773chr17:59924581ENST00000510283-12766_16601178.0Coiled coilOntology_term=ECO:0000255
HgeneSPAG9chr17:49133773chr17:59924581ENST00000510283-127724_75801178.0Coiled coilOntology_term=ECO:0000255
HgeneSPAG9chr17:49133772chr17:59924581ENST00000262013-330500_5711651322.0DomainRH2
HgeneSPAG9chr17:49133772chr17:59924581ENST00000357122-329500_5711651308.0DomainRH2
HgeneSPAG9chr17:49133772chr17:59924581ENST00000505279-330500_5711651312.0DomainRH2
HgeneSPAG9chr17:49133772chr17:59924581ENST00000510283-127500_57101178.0DomainRH2
HgeneSPAG9chr17:49133772chr17:59924581ENST00000510283-1277_9501178.0DomainRH1
HgeneSPAG9chr17:49133773chr17:59924581ENST00000262013-330500_5711651322.0DomainRH2
HgeneSPAG9chr17:49133773chr17:59924581ENST00000357122-329500_5711651308.0DomainRH2
HgeneSPAG9chr17:49133773chr17:59924581ENST00000505279-330500_5711651312.0DomainRH2
HgeneSPAG9chr17:49133773chr17:59924581ENST00000510283-127500_57101178.0DomainRH2
HgeneSPAG9chr17:49133773chr17:59924581ENST00000510283-1277_9501178.0DomainRH1
TgeneBRIP1chr17:49133772chr17:59924581ENST0000025900842011_4421691250.0DomainHelicase ATP-binding
TgeneBRIP1chr17:49133773chr17:59924581ENST0000025900842011_4421691250.0DomainHelicase ATP-binding
TgeneBRIP1chr17:49133772chr17:59924581ENST00000259008420158_1751691250.0MotifNuclear localization signal
TgeneBRIP1chr17:49133773chr17:59924581ENST00000259008420158_1751691250.0MotifNuclear localization signal


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Fusion Gene Sequence for SPAG9-BRIP1


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>85454_85454_1_SPAG9-BRIP1_SPAG9_chr17_49133772_ENST00000262013_BRIP1_chr17_59924581_ENST00000259008_length(transcript)=5977nt_BP=704nt
AGTTGGTGCAGCGGCGGTTGGGGTGAGAGCGCCTACGCCACCCCTCCCCTCCTCCGGCCCCGGCCCCCACCCCGCCGGGCCCAGCCCCAG
CCCCGGCCCGGGCTCCAGCCCTAGTACCCGTCCCAGCCCGAGTCGGGTCCGTCCCGTGCGGGCAGGTGCCGCCCCTCTGCCGGCGACGCC
CCGGGCCGCCCGCCCGTCCGCTTGCCACCATGGAGCTGGAGGACGGTGTGGTGTATCAGGAGGAGCCCGGCGGCTCCGGGGCCGTGATGT
CGGAGCGGGTGTCCGGCCTGGCCGGCTCCATCTACCGCGAGTTCGAGCGGCTTATCGGGCGCTATGACGAGGAGGTGGTCAAAGAGCTGA
TGCCGCTGGTGGTGGCTGTGCTGGAGAACCTGGACTCGGTGTTCGCGCAGGACCAGGAGCACCAGGTGGAGCTGGAGCTGCTGCGGGACG
ACAACGAGCAGCTCATCACCCAGTACGAGCGGGAGAAGGCGCTGCGCAAGCACGCTGAGGAGAAATTCATTGAATTTGAAGACTCTCAAG
AACAGGAAAAAAAGGACTTACAGACCCGAGTGGAATCTTTAGAATCTCAAACAAGACAACTTGAGCTGAAAGCGAAAAACTATGCTGACC
AGATTAGCAGACTTGAAGAAAGAGAAGCAGAACTGAAGAAGGAATATAATGCATTACATCAAAGACACACTGAGATTAGAAAACGTCATT
GCTTTGGAACAGAAGTACACAATTTGGATGCAAAAGTTGATTCAGGAAAGACTGTAAAACTCAACTCTCCACTGGAAAAGATAAACTCCT
TTTCGCCACAGAAACCCCCTGGCCACTGTTCTAGGTGCTGTTGTTCTACTAAACAAGGAAACAGTCAAGAGTCATCGAATACCATTAAGA
AGGATCATACAGGGAAATCCAAGATACCCAAAATATATTTTGGGACACGCACACACAAGCAGATTGCTCAGATTACTAGAGAGCTCCGGA
GGACGGCATATTCAGGGGTTCCAATGACTATTCTTTCCAGCAGGGATCATACTTGTGTCCATCCTGAGGTAGTCGGTAACTTCAACAGAA
ATGAGAAGTGCATGGAATTGCTAGATGGGAAAAACGGAAAATCCTGCTATTTTTATCATGGAGTTCATAAAATTAGTGATCAGCACACAT
TACAGACTTTCCAAGGGATGTGCAAAGCCTGGGATATAGAAGAACTTGTCAGCCTGGGGAAGAAACTAAAGGCCTGTCCATATTACACAG
CCCGAGAACTAATACAAGATGCTGACATCATATTTTGTCCCTACAACTATCTTCTAGATGCACAAATAAGGGAAAGTATGGATTTAAATC
TGAAAGAACAGGTTGTCATTTTAGATGAAGCTCATAACATCGAGGACTGTGCTCGGGAATCAGCAAGTTACAGTGTAACAGAAGTTCAGC
TTCGGTTTGCTCGGGATGAACTAGATAGTATGGTCAACAATAATATAAGGAAGAAAGATCATGAACCCCTACGAGCTGTGTGCTGTAGCC
TCATTAATTGGTTAGAAGCAAACGCTGAATATCTTGTAGAAAGAGATTATGAATCAGCTTGTAAAATATGGAGTGGAAATGAAATGCTCT
TAACTTTACACAAAATGGGTATCACCACTGCTACTTTTCCCATTTTGCAGGGACATTTTTCTGCTGTTCTTCAAAAAGAGGAAAAAATCT
CACCAATTTATGGTAAAGAGGAGGCAAGAGAAGTACCTGTTATTAGTGCATCAACTCAAATAATGCTTAAAGGACTTTTTATGGTACTTG
ACTATCTTTTTAGGCAAAATAGCAGATTTGCAGATGATTATAAAATTGCGATTCAACAGACTTACTCCTGGACAAATCAGATTGATATTT
CAGACAAAAATGGGTTGTTGGTTCTACCAAAAAATAAGAAACGTTCACGACAGAAAACTGCAGTTCATGTGCTAAACTTTTGGTGCTTAA
ATCCAGCTGTGGCCTTTTCAGATATTAATGGCAAAGTTCAGACCATTGTTTTGACATCTGGTACATTATCACCAATGAAATCCTTTTCGT
CAGAACTTGGTGTTACATTTACTATCCAGCTGGAGGCTAATCATATCATTAAAAATTCACAGGTTTGGGTTGGTACCATTGGGTCAGGCC
CCAAGGGTCGGAATCTCTGTGCTACCTTCCAGAATACTGAAACATTTGAGTTCCAAGATGAAGTGGGAGCACTTTTGTTATCTGTGTGCC
AGACTGTGAGCCAAGGAATTTTGTGTTTCTTGCCATCTTACAAGTTATTAGAAAAATTAAAAGAACGTTGGCTCTCTACTGGTTTATGGC
ATAATCTGGAGTTGGTGAAGACAGTCATTGTAGAACCACAGGGAGGAGAAAAAACAAATTTTGATGAATTACTGCAGGTGTACTATGACG
CAATCAAATACAAAGGAGAGAAAGATGGAGCTCTCCTGGTAGCAGTTTGTCGTGGTAAAGTGAGTGAGGGTCTGGATTTCTCAGATGACA
ATGCCCGTGCTGTCATAACAATAGGAATTCCTTTTCCAAATGTGAAAGATCTACAGGTTGAACTAAAACGACAATACAATGACCACCATT
CAAAATTGAGAGGTCTTCTACCTGGCCGTCAGTGGTATGAAATTCAAGCATACAGGGCCTTAAACCAGGCCCTTGGTAGATGTATTAGAC
ACAGAAATGATTGGGGAGCTCTTATTCTAGTGGATGATCGCTTTAGGAATAACCCAAGTCGCTATATATCTGGACTTTCTAAATGGGTAC
GGCAGCAGATTCAGCACCATTCAACCTTTGAAAGTGCACTGGAATCCTTGGCTGAATTTTCCAAAAAGCATCAAAAAGTTCTTAATGTAT
CCATAAAGGACAGAACCAATATACAGGACAATGAGTCTACACTTGAAGTGACCTCTTTAAAGTACAGTACCTCACCTTATTTACTGGAAG
CAGCAAGTCATCTATCACCAGAAAATTTTGTGGAAGATGAAGCAAAGATATGTGTCCAGGAACTACAGTGTCCTAAAATTATTACCAAAA
ATTCACCTCTACCAAGTAGCATTATCTCCAGAAAGGAGAAAAATGATCCAGTATTCCTGGAAGAAGCAGGGAAAGCAGAAAAAATTGTGA
TTTCCAGATCCACAAGCCCAACTTTCAACAAACAAACAAAGAGAGTTAGCTGGTCAAGCTTTAATTCTTTGGGACAGTATTTTACTGGTA
AAATACCGAAGGCAACACCTGAGCTCGGGTCATCAGAGAATAGTGCCTCTAGTCCTCCCCGTTTCAAAACAGAGAAGATGGAAAGTAAAA
CTGTTTTGCCCTTCACTGATAAATGTGAATCCTCAAATCTGACAGTAAACACATCGTTTGGATCATGCCCTCAATCAGAAACCATTATTT
CATCATTAAAGATTGATGCCACCCTTACTAGAAAAAATCATTCTGAACATCCGCTCTGTTCTGAAGAAGCCCTGGATCCAGACATTGAAT
TGTCTCTAGTAAGTGAAGAAGATAAACAGTCCACTTCAAATAGAGATTTTGAAACAGAAGCAGAAGATGAATCTATCTATTTTACACCTG
AACTTTATGATCCTGAAGATACAGATGAAGAAAAAAATGACCTAGCTGAAACTGATAGAGGAAATAGATTGGCTAACAATTCAGATTGCA
TTTTAGCTAAAGACCTTTTTGAAATTAGAACTATAAAAGAAGTAGATTCAGCCAGAGAAGTGAAAGCTGAGGATTGCATAGATACAAAGT
TGAATGGAATTCTGCATATTGAAGAAAGTAAAATTGATGACATTGATGGTAATGTAAAAACAACTTGGATAAATGAACTGGAACTGGGAA
AAACTCATGAAATAGAAATAAAGAACTTTAAACCATCTCCTTCCAAAAATAAAGGCATGTTTCCTGGTTTTAAGTAATAATACTTAACTC
TCAAGCTAAGTAAAAATATGTCATCATGCTTATGTTAAACTCTGTTGTAAGTAATAATTTGTAAATTGAATAAGTGGCATACTTTTTAAA
AAACTATTTTATGTTCAGAAATGTAAATGTTATTATTCTTGAGTTTTTGGGTTTTTTTTTTTGAGACAGAGTCTTGGTCTGTTGCCCAGG
CTGGAATGCAGTGGTGTGCTCTGGGCTCACTGCAACCTTCACCTCCAGGTTCAAGTGATTCTCCTGCCTCAGCCTTCTGAGTAGCTGGGA
CTACAGGTGTGCACCACCATGCCCAGCTAGTTTTTGTATTTTTAGTAGAGATGGGGTTTCACCATGTTGGCCAGGCTGGTCTCGAACTCC
TGGCCTCGTGATCTGCCCTTCTCTGCCTCCCTAAGTTGCTGGGATTACAGGTGTGAGCCACAGTGCCTGGCCCATTCTTGAGTTTTGATA
AAGTAATTCATACAAAGTACTGTCCTCAAATAAGTCTTCCTTAGCTAAATGCAATTTAAAATTATTCAAAGATCCTAGGGCACTTCTAGT
TTCACGTAAATATTCATATTAGGTGGTTCTCTTCATCCATTTGTTTTCACACTGATACATAAAAATTAACAGCAGTCTAATCTAGTGACA
CCTCAGTCATATTTCGCTATAGATTTTACCTCAAATCAGTCCAAGACTTTTTCAGAGATCACCATTTGTCTTGAAAGGTTTATTTCGTTA
TTAAACTGCCTACTTATAAGTAATTAAGAGAAATTAAGAAAGTAGTATGCATTTTTAATTGAAATTGTTTTACATTCTTTGTATAATAAA
CCTAAAACCAAACATGTCATAAACAAATTGACGTAAAGATATAAAATGCCAAATGAAGTATTCCAAATTTTCTATTCTAATTATTTAGCT
TCACCATCATTGTGGAAAAAAATACTAGATCCTGCTTAGTATTATATATTTTTCCTAGTGGATCAGTGAGTAATAAGTACCAAACACTAG
ACTAGAAGGTAATTTCTACATTGTTTAGAAAGGGTGAAACAATTTATCCCCTCTGGTATTGTTCTAGCATAAGCTTTAGTTATACAATGA
TTAAGATAGAAAACTTCATATATAAATTTGATAAGCAAACCCACATTTATAGCTGCAGCTAAAATATGTTTCCTTAGGGCACAGTAATCC
TTTCTGTGAATTTTGACCTTGTTTGTGTTTTTGTGAATGAAGCTATATGTCTAATCAAAAATGATTATAAAAGAGGCTCATCTCTGACAT
CATTCCAAAAATACATTCATTGATCTCTTTTTAAGAAACATCTGTTATTCACTGGGCATTGGGACTTTTTGTGAGTAATTTGAATTGAAA
TTTTATGAGCTATCCAAGAATTCTGTATGGTCTATTATTTTCAAGTCAAAATTTCCAGTAAGGATTTACTTTACATTTCATTTGGATAAA
TGAATCATTATATAGGTATGTCTTTGCTTCCATTTTGAGACATTTAGATTTTTACAGCCTGTTTCTATAGCATTTGATGTTACAACTCTA
AGCGTAGTTCAAAGACATTTAAATTGACAAGTTACCAGTTAAAGAATTTAGAATATATTAGATCCCATCTAGTATTATATATTTTTTCTA
GTTGATCATTGAGCAGTAAATACCAAATACTCGATTAGAAGGTAATTTTTACATTGTTTTGAAAGGGTGAAACAATTTATCTCCTCTGGT
ATTATTCTTAAACCACAGATAGGGATAGTAGGGTAGTGAAACGAATAAATACCTGGTAGAAGACAAGAGACTTGGGCTCTACACCTGGCT
CTGCCACTGATTTGCTAAGTCATATTGGCAATCACCACACCCTTCAGGGAATTAGTTTCATCTGTAAAATGCAGCGGTTAGTACTATAAA
ATCATACAAATTTCTTTGTGCTTTGAGAATCTATAAAGGAATGTCTGTTGATATTCTGAGTCGATTTTCATTTGCTTTTGTTCCAGAACG

>85454_85454_1_SPAG9-BRIP1_SPAG9_chr17_49133772_ENST00000262013_BRIP1_chr17_59924581_ENST00000259008_length(amino acids)=1245AA_BP=165
MELEDGVVYQEEPGGSGAVMSERVSGLAGSIYREFERLIGRYDEEVVKELMPLVVAVLENLDSVFAQDQEHQVELELLRDDNEQLITQYE
REKALRKHAEEKFIEFEDSQEQEKKDLQTRVESLESQTRQLELKAKNYADQISRLEEREAELKKEYNALHQRHTEIRKRHCFGTEVHNLD
AKVDSGKTVKLNSPLEKINSFSPQKPPGHCSRCCCSTKQGNSQESSNTIKKDHTGKSKIPKIYFGTRTHKQIAQITRELRRTAYSGVPMT
ILSSRDHTCVHPEVVGNFNRNEKCMELLDGKNGKSCYFYHGVHKISDQHTLQTFQGMCKAWDIEELVSLGKKLKACPYYTARELIQDADI
IFCPYNYLLDAQIRESMDLNLKEQVVILDEAHNIEDCARESASYSVTEVQLRFARDELDSMVNNNIRKKDHEPLRAVCCSLINWLEANAE
YLVERDYESACKIWSGNEMLLTLHKMGITTATFPILQGHFSAVLQKEEKISPIYGKEEAREVPVISASTQIMLKGLFMVLDYLFRQNSRF
ADDYKIAIQQTYSWTNQIDISDKNGLLVLPKNKKRSRQKTAVHVLNFWCLNPAVAFSDINGKVQTIVLTSGTLSPMKSFSSELGVTFTIQ
LEANHIIKNSQVWVGTIGSGPKGRNLCATFQNTETFEFQDEVGALLLSVCQTVSQGILCFLPSYKLLEKLKERWLSTGLWHNLELVKTVI
VEPQGGEKTNFDELLQVYYDAIKYKGEKDGALLVAVCRGKVSEGLDFSDDNARAVITIGIPFPNVKDLQVELKRQYNDHHSKLRGLLPGR
QWYEIQAYRALNQALGRCIRHRNDWGALILVDDRFRNNPSRYISGLSKWVRQQIQHHSTFESALESLAEFSKKHQKVLNVSIKDRTNIQD
NESTLEVTSLKYSTSPYLLEAASHLSPENFVEDEAKICVQELQCPKIITKNSPLPSSIISRKEKNDPVFLEEAGKAEKIVISRSTSPTFN
KQTKRVSWSSFNSLGQYFTGKIPKATPELGSSENSASSPPRFKTEKMESKTVLPFTDKCESSNLTVNTSFGSCPQSETIISSLKIDATLT
RKNHSEHPLCSEEALDPDIELSLVSEEDKQSTSNRDFETEAEDESIYFTPELYDPEDTDEEKNDLAETDRGNRLANNSDCILAKDLFEIR

--------------------------------------------------------------
>85454_85454_2_SPAG9-BRIP1_SPAG9_chr17_49133772_ENST00000262013_BRIP1_chr17_59924581_ENST00000577598_length(transcript)=4166nt_BP=704nt
AGTTGGTGCAGCGGCGGTTGGGGTGAGAGCGCCTACGCCACCCCTCCCCTCCTCCGGCCCCGGCCCCCACCCCGCCGGGCCCAGCCCCAG
CCCCGGCCCGGGCTCCAGCCCTAGTACCCGTCCCAGCCCGAGTCGGGTCCGTCCCGTGCGGGCAGGTGCCGCCCCTCTGCCGGCGACGCC
CCGGGCCGCCCGCCCGTCCGCTTGCCACCATGGAGCTGGAGGACGGTGTGGTGTATCAGGAGGAGCCCGGCGGCTCCGGGGCCGTGATGT
CGGAGCGGGTGTCCGGCCTGGCCGGCTCCATCTACCGCGAGTTCGAGCGGCTTATCGGGCGCTATGACGAGGAGGTGGTCAAAGAGCTGA
TGCCGCTGGTGGTGGCTGTGCTGGAGAACCTGGACTCGGTGTTCGCGCAGGACCAGGAGCACCAGGTGGAGCTGGAGCTGCTGCGGGACG
ACAACGAGCAGCTCATCACCCAGTACGAGCGGGAGAAGGCGCTGCGCAAGCACGCTGAGGAGAAATTCATTGAATTTGAAGACTCTCAAG
AACAGGAAAAAAAGGACTTACAGACCCGAGTGGAATCTTTAGAATCTCAAACAAGACAACTTGAGCTGAAAGCGAAAAACTATGCTGACC
AGATTAGCAGACTTGAAGAAAGAGAAGCAGAACTGAAGAAGGAATATAATGCATTACATCAAAGACACACTGAGATTAGAAAACGTCATT
GCTTTGGAACAGAAGTACACAATTTGGATGCAAAAGTTGATTCAGGAAAGACTGTAAAACTCAACTCTCCACTGGAAAAGATAAACTCCT
TTTCGCCACAGAAACCCCCTGGCCACTGTTCTAGGTGCTGTTGTTCTACTAAACAAGGAAACAGTCAAGAGTCATCGAATACCATTAAGA
AGGATCATACAGGGAAATCCAAGATACCCAAAATATATTTTGGGACACGCACACACAAGCAGATTGCTCAGATTACTAGAGAGCTCCGGA
GGACGGCATATTCAGGGGTTCCAATGACTATTCTTTCCAGCAGGGATCATACTTGTGTCCATCCTGAGGTAGTCGGTAACTTCAACAGAA
ATGAGAAGTGCATGGAATTGCTAGATGGGAAAAACGGAAAATCCTGCTATTTTTATCATGGAGTTCATAAAATTAGTGATCAGCACACAT
TACAGACTTTCCAAGGGATGTGCAAAGCCTGGGATATAGAAGAACTTGTCAGCCTGGGGAAGAAACTAAAGGCCTGTCCATATTACACAG
CCCGAGAACTAATACAAGATGCTGACATCATATTTTGTCCCTACAACTATCTTCTAGATGCACAAATAAGGGAAAGTATGGATTTAAATC
TGAAAGAACAGGTTGTCATTTTAGATGAAGCTCATAACATCGAGGACTGTGCTCGGGAATCAGCAAGTTACAGTGTAACAGAAGTTCAGC
TTCGGTTTGCTCGGGATGAACTAGATAGTATGGTCAACAATAATATAAGGAAGAAAGATCATGAACCCCTACGAGCTGTGTGCTGTAGCC
TCATTAATTGGTTAGAAGCAAACGCTGAATATCTTGTAGAAAGAGATTATGAATCAGCTTGTAAAATATGGAGTGGAAATGAAATGCTCT
TAACTTTACACAAAATGGGTATCACCACTGCTACTTTTCCCATTTTGCAGGGACATTTTTCTGCTGTTCTTCAAAAAGAGGAAAAAATCT
CACCAATTTATGGTAAAGAGGAGGCAAGAGAAGTACCTGTTATTAGTGCATCAACTCAAATAATGCTTAAAGGACTTTTTATGGTACTTG
ACTATCTTTTTAGGCAAAATAGCAGATTTGCAGATGATTATAAAATTGCGATTCAACAGACTTACTCCTGGACAAATCAGATTGATATTT
CAGACAAAAATGGGTTGTTGGTTCTACCAAAAAATAAGAAACGTTCACGACAGAAAACTGCAGTTCATGTGCTAAACTTTTGGTGCTTAA
ATCCAGCTGTGGCCTTTTCAGATATTAATGGCAAAGTTCAGACCATTGTTTTGACATCTGGTACATTATCACCAATGAAATCCTTTTCGT
CAGAACTTGGTGTTACATTTACTATCCAGCTGGAGGCTAATCATATCATTAAAAATTCACAGGTTTGGGTTGGTACCATTGGGTCAGGCC
CCAAGGGTCGGAATCTCTGTGCTACCTTCCAGAATACTGAAACATTTGAGTTCCAAGATGAAGTGGGAGCACTTTTGTTATCTGTGTGCC
AGACTGTGAGCCAAGGAATTTTGTGTTTCTTGCCATCTTACAAGTTATTAGAAAAATTAAAAGAACGTTGGCTCTCTACTGGTTTATGGC
ATAATCTGGAGTTGGTGAAGACAGTCATTGTAGAACCACAGGGAGGAGAAAAAACAAATTTTGATGAATTACTGCAGGTGTACTATGACG
CAATCAAATACAAAGGAGAGAAAGATGGAGCTCTCCTGGTAGCAGTTTGTCGTGGTAAAGTGAGTGAGGGTCTGGATTTCTCAGATGACA
ATGCCCGTGCTGTCATAACAATAGGAATTCCTTTTCCAAATGTGAAAGATCTACAGGTTGAACTAAAACGACAATACAATGACCACCATT
CAAAATTGAGAGGTCTTCTACCTGGCCGTCAGTGGTATGAAATTCAAGCATACAGGGCCTTAAACCAGGCCCTTGGTAGATGTATTAGAC
ACAGAAATGATTGGGGAGCTCTTATTCTAGTGGATGATCGCTTTAGGAATAACCCAAGTCGCTATATATCTGGACTTTCTAAATGGGTAC
GGCAGCAGATTCAGCACCATTCAACCTTTGAAAGTGCACTGGAATCCTTGGCTGAATTTTCCAAAAAGCATCAAAAAGTTCTTAATGTAT
CCATAAAGGACAGAACCAATATACAGGACAATGAGTCTACACTTGAAGTGACCTCTTTAAAGTACAGTACCTCACCTTATTTACTGGAAG
CAGCAAGTCATCTATCACCAGAAAATTTTGTGGAAGATGAAGCAAAGATATGTGTCCAGGAACTACAGTGTCCTAAAATTATTACCAAAA
ATTCACCTCTACCAAGTAGCATTATCTCCAGAAAGGAGAAAAGTATGAAAAGTTCTTCCCATTTACCTTTGATAGAGAAGTCTTTCATTA
TATTTAGTGAAATGATATTTATTTGGGTATAGATTAATTCCTTAAATATGGTGGTTTGTAATATAAGGTGTTATCATAAAATAGTGAAAC
AGTATGGTGTACTGTAATGGGAACAAACTTTTGTCAGGAGACCAGAGCATATTTTCTGGTTTTCCACTAACTGGCTTTGCCACTTACTAG
CTTTGTGATCATGAGCAAGTCATTTGTCCTTTTTGAGTCGTAATAGGAAAAAAAAAATGCCTGCCTAGCTATCCCTTCAGGTTGGGTTGT
AAAGGTCAAAATTATAAATATCACAGCATTGTAAAGTACCATGTAAGTGGTAGATGTTATTCTAAAGGCTATATAAAAATTTGGCCTAAT
TTTTATGTAGATACTTCTATATGAACTACTTTTCCTATATAGATAGTTCTTATGAACTTATTTTTAGGAGGTGAGAGACATTTATTTTAA
GTGATGAAAAATAATATTTTAAAATATTTTGAAATAATCATCTGTATCAGATTGGCAAACTGTGGCCCATGGGCCAAATTTGGCCTGCTG
CCTGTTTTTGTAAATAAAGTTTAATGAAATGTAGTCATGCCCATTTATTTACATTTTAGAAACAACAGCAGAGTTGAGTATTTGTGTGTA
TTGCACTAGAACAGCATAATTGAGTAGTCGCAACAGATACATTATGCTCCACAAAGCCTAAATATTACTATCTGGCCTATGACAGAAAAG
GTTTGCCAAACTCTGGTCTATTCCATTGGATATAATTTCAGTTGTTTTAATTCATATATCCAAGGCGGGTGGATCATCCGAGGTCAGGAG
TCCGAGACCAGCCTGACCAGTGTGGTGAAACACCGTCTCTACTAAAAAAATACAAAAATTAGCTGGGTGTGGAGGCAGCTGTCTGTAATC
CCAGCTACTCAGGAGGCTGAGGCAGGAGAATTGCTTGAACTGGGAGGTGGAGGTTGCAGTGAGCCAGGATTGCGCCATTGCACTCCAGCC

>85454_85454_2_SPAG9-BRIP1_SPAG9_chr17_49133772_ENST00000262013_BRIP1_chr17_59924581_ENST00000577598_length(amino acids)=990AA_BP=165
MELEDGVVYQEEPGGSGAVMSERVSGLAGSIYREFERLIGRYDEEVVKELMPLVVAVLENLDSVFAQDQEHQVELELLRDDNEQLITQYE
REKALRKHAEEKFIEFEDSQEQEKKDLQTRVESLESQTRQLELKAKNYADQISRLEEREAELKKEYNALHQRHTEIRKRHCFGTEVHNLD
AKVDSGKTVKLNSPLEKINSFSPQKPPGHCSRCCCSTKQGNSQESSNTIKKDHTGKSKIPKIYFGTRTHKQIAQITRELRRTAYSGVPMT
ILSSRDHTCVHPEVVGNFNRNEKCMELLDGKNGKSCYFYHGVHKISDQHTLQTFQGMCKAWDIEELVSLGKKLKACPYYTARELIQDADI
IFCPYNYLLDAQIRESMDLNLKEQVVILDEAHNIEDCARESASYSVTEVQLRFARDELDSMVNNNIRKKDHEPLRAVCCSLINWLEANAE
YLVERDYESACKIWSGNEMLLTLHKMGITTATFPILQGHFSAVLQKEEKISPIYGKEEAREVPVISASTQIMLKGLFMVLDYLFRQNSRF
ADDYKIAIQQTYSWTNQIDISDKNGLLVLPKNKKRSRQKTAVHVLNFWCLNPAVAFSDINGKVQTIVLTSGTLSPMKSFSSELGVTFTIQ
LEANHIIKNSQVWVGTIGSGPKGRNLCATFQNTETFEFQDEVGALLLSVCQTVSQGILCFLPSYKLLEKLKERWLSTGLWHNLELVKTVI
VEPQGGEKTNFDELLQVYYDAIKYKGEKDGALLVAVCRGKVSEGLDFSDDNARAVITIGIPFPNVKDLQVELKRQYNDHHSKLRGLLPGR
QWYEIQAYRALNQALGRCIRHRNDWGALILVDDRFRNNPSRYISGLSKWVRQQIQHHSTFESALESLAEFSKKHQKVLNVSIKDRTNIQD
NESTLEVTSLKYSTSPYLLEAASHLSPENFVEDEAKICVQELQCPKIITKNSPLPSSIISRKEKSMKSSSHLPLIEKSFIIFSEMIFIWV

--------------------------------------------------------------
>85454_85454_3_SPAG9-BRIP1_SPAG9_chr17_49133772_ENST00000357122_BRIP1_chr17_59924581_ENST00000259008_length(transcript)=5977nt_BP=704nt
AGTTGGTGCAGCGGCGGTTGGGGTGAGAGCGCCTACGCCACCCCTCCCCTCCTCCGGCCCCGGCCCCCACCCCGCCGGGCCCAGCCCCAG
CCCCGGCCCGGGCTCCAGCCCTAGTACCCGTCCCAGCCCGAGTCGGGTCCGTCCCGTGCGGGCAGGTGCCGCCCCTCTGCCGGCGACGCC
CCGGGCCGCCCGCCCGTCCGCTTGCCACCATGGAGCTGGAGGACGGTGTGGTGTATCAGGAGGAGCCCGGCGGCTCCGGGGCCGTGATGT
CGGAGCGGGTGTCCGGCCTGGCCGGCTCCATCTACCGCGAGTTCGAGCGGCTTATCGGGCGCTATGACGAGGAGGTGGTCAAAGAGCTGA
TGCCGCTGGTGGTGGCTGTGCTGGAGAACCTGGACTCGGTGTTCGCGCAGGACCAGGAGCACCAGGTGGAGCTGGAGCTGCTGCGGGACG
ACAACGAGCAGCTCATCACCCAGTACGAGCGGGAGAAGGCGCTGCGCAAGCACGCTGAGGAGAAATTCATTGAATTTGAAGACTCTCAAG
AACAGGAAAAAAAGGACTTACAGACCCGAGTGGAATCTTTAGAATCTCAAACAAGACAACTTGAGCTGAAAGCGAAAAACTATGCTGACC
AGATTAGCAGACTTGAAGAAAGAGAAGCAGAACTGAAGAAGGAATATAATGCATTACATCAAAGACACACTGAGATTAGAAAACGTCATT
GCTTTGGAACAGAAGTACACAATTTGGATGCAAAAGTTGATTCAGGAAAGACTGTAAAACTCAACTCTCCACTGGAAAAGATAAACTCCT
TTTCGCCACAGAAACCCCCTGGCCACTGTTCTAGGTGCTGTTGTTCTACTAAACAAGGAAACAGTCAAGAGTCATCGAATACCATTAAGA
AGGATCATACAGGGAAATCCAAGATACCCAAAATATATTTTGGGACACGCACACACAAGCAGATTGCTCAGATTACTAGAGAGCTCCGGA
GGACGGCATATTCAGGGGTTCCAATGACTATTCTTTCCAGCAGGGATCATACTTGTGTCCATCCTGAGGTAGTCGGTAACTTCAACAGAA
ATGAGAAGTGCATGGAATTGCTAGATGGGAAAAACGGAAAATCCTGCTATTTTTATCATGGAGTTCATAAAATTAGTGATCAGCACACAT
TACAGACTTTCCAAGGGATGTGCAAAGCCTGGGATATAGAAGAACTTGTCAGCCTGGGGAAGAAACTAAAGGCCTGTCCATATTACACAG
CCCGAGAACTAATACAAGATGCTGACATCATATTTTGTCCCTACAACTATCTTCTAGATGCACAAATAAGGGAAAGTATGGATTTAAATC
TGAAAGAACAGGTTGTCATTTTAGATGAAGCTCATAACATCGAGGACTGTGCTCGGGAATCAGCAAGTTACAGTGTAACAGAAGTTCAGC
TTCGGTTTGCTCGGGATGAACTAGATAGTATGGTCAACAATAATATAAGGAAGAAAGATCATGAACCCCTACGAGCTGTGTGCTGTAGCC
TCATTAATTGGTTAGAAGCAAACGCTGAATATCTTGTAGAAAGAGATTATGAATCAGCTTGTAAAATATGGAGTGGAAATGAAATGCTCT
TAACTTTACACAAAATGGGTATCACCACTGCTACTTTTCCCATTTTGCAGGGACATTTTTCTGCTGTTCTTCAAAAAGAGGAAAAAATCT
CACCAATTTATGGTAAAGAGGAGGCAAGAGAAGTACCTGTTATTAGTGCATCAACTCAAATAATGCTTAAAGGACTTTTTATGGTACTTG
ACTATCTTTTTAGGCAAAATAGCAGATTTGCAGATGATTATAAAATTGCGATTCAACAGACTTACTCCTGGACAAATCAGATTGATATTT
CAGACAAAAATGGGTTGTTGGTTCTACCAAAAAATAAGAAACGTTCACGACAGAAAACTGCAGTTCATGTGCTAAACTTTTGGTGCTTAA
ATCCAGCTGTGGCCTTTTCAGATATTAATGGCAAAGTTCAGACCATTGTTTTGACATCTGGTACATTATCACCAATGAAATCCTTTTCGT
CAGAACTTGGTGTTACATTTACTATCCAGCTGGAGGCTAATCATATCATTAAAAATTCACAGGTTTGGGTTGGTACCATTGGGTCAGGCC
CCAAGGGTCGGAATCTCTGTGCTACCTTCCAGAATACTGAAACATTTGAGTTCCAAGATGAAGTGGGAGCACTTTTGTTATCTGTGTGCC
AGACTGTGAGCCAAGGAATTTTGTGTTTCTTGCCATCTTACAAGTTATTAGAAAAATTAAAAGAACGTTGGCTCTCTACTGGTTTATGGC
ATAATCTGGAGTTGGTGAAGACAGTCATTGTAGAACCACAGGGAGGAGAAAAAACAAATTTTGATGAATTACTGCAGGTGTACTATGACG
CAATCAAATACAAAGGAGAGAAAGATGGAGCTCTCCTGGTAGCAGTTTGTCGTGGTAAAGTGAGTGAGGGTCTGGATTTCTCAGATGACA
ATGCCCGTGCTGTCATAACAATAGGAATTCCTTTTCCAAATGTGAAAGATCTACAGGTTGAACTAAAACGACAATACAATGACCACCATT
CAAAATTGAGAGGTCTTCTACCTGGCCGTCAGTGGTATGAAATTCAAGCATACAGGGCCTTAAACCAGGCCCTTGGTAGATGTATTAGAC
ACAGAAATGATTGGGGAGCTCTTATTCTAGTGGATGATCGCTTTAGGAATAACCCAAGTCGCTATATATCTGGACTTTCTAAATGGGTAC
GGCAGCAGATTCAGCACCATTCAACCTTTGAAAGTGCACTGGAATCCTTGGCTGAATTTTCCAAAAAGCATCAAAAAGTTCTTAATGTAT
CCATAAAGGACAGAACCAATATACAGGACAATGAGTCTACACTTGAAGTGACCTCTTTAAAGTACAGTACCTCACCTTATTTACTGGAAG
CAGCAAGTCATCTATCACCAGAAAATTTTGTGGAAGATGAAGCAAAGATATGTGTCCAGGAACTACAGTGTCCTAAAATTATTACCAAAA
ATTCACCTCTACCAAGTAGCATTATCTCCAGAAAGGAGAAAAATGATCCAGTATTCCTGGAAGAAGCAGGGAAAGCAGAAAAAATTGTGA
TTTCCAGATCCACAAGCCCAACTTTCAACAAACAAACAAAGAGAGTTAGCTGGTCAAGCTTTAATTCTTTGGGACAGTATTTTACTGGTA
AAATACCGAAGGCAACACCTGAGCTCGGGTCATCAGAGAATAGTGCCTCTAGTCCTCCCCGTTTCAAAACAGAGAAGATGGAAAGTAAAA
CTGTTTTGCCCTTCACTGATAAATGTGAATCCTCAAATCTGACAGTAAACACATCGTTTGGATCATGCCCTCAATCAGAAACCATTATTT
CATCATTAAAGATTGATGCCACCCTTACTAGAAAAAATCATTCTGAACATCCGCTCTGTTCTGAAGAAGCCCTGGATCCAGACATTGAAT
TGTCTCTAGTAAGTGAAGAAGATAAACAGTCCACTTCAAATAGAGATTTTGAAACAGAAGCAGAAGATGAATCTATCTATTTTACACCTG
AACTTTATGATCCTGAAGATACAGATGAAGAAAAAAATGACCTAGCTGAAACTGATAGAGGAAATAGATTGGCTAACAATTCAGATTGCA
TTTTAGCTAAAGACCTTTTTGAAATTAGAACTATAAAAGAAGTAGATTCAGCCAGAGAAGTGAAAGCTGAGGATTGCATAGATACAAAGT
TGAATGGAATTCTGCATATTGAAGAAAGTAAAATTGATGACATTGATGGTAATGTAAAAACAACTTGGATAAATGAACTGGAACTGGGAA
AAACTCATGAAATAGAAATAAAGAACTTTAAACCATCTCCTTCCAAAAATAAAGGCATGTTTCCTGGTTTTAAGTAATAATACTTAACTC
TCAAGCTAAGTAAAAATATGTCATCATGCTTATGTTAAACTCTGTTGTAAGTAATAATTTGTAAATTGAATAAGTGGCATACTTTTTAAA
AAACTATTTTATGTTCAGAAATGTAAATGTTATTATTCTTGAGTTTTTGGGTTTTTTTTTTTGAGACAGAGTCTTGGTCTGTTGCCCAGG
CTGGAATGCAGTGGTGTGCTCTGGGCTCACTGCAACCTTCACCTCCAGGTTCAAGTGATTCTCCTGCCTCAGCCTTCTGAGTAGCTGGGA
CTACAGGTGTGCACCACCATGCCCAGCTAGTTTTTGTATTTTTAGTAGAGATGGGGTTTCACCATGTTGGCCAGGCTGGTCTCGAACTCC
TGGCCTCGTGATCTGCCCTTCTCTGCCTCCCTAAGTTGCTGGGATTACAGGTGTGAGCCACAGTGCCTGGCCCATTCTTGAGTTTTGATA
AAGTAATTCATACAAAGTACTGTCCTCAAATAAGTCTTCCTTAGCTAAATGCAATTTAAAATTATTCAAAGATCCTAGGGCACTTCTAGT
TTCACGTAAATATTCATATTAGGTGGTTCTCTTCATCCATTTGTTTTCACACTGATACATAAAAATTAACAGCAGTCTAATCTAGTGACA
CCTCAGTCATATTTCGCTATAGATTTTACCTCAAATCAGTCCAAGACTTTTTCAGAGATCACCATTTGTCTTGAAAGGTTTATTTCGTTA
TTAAACTGCCTACTTATAAGTAATTAAGAGAAATTAAGAAAGTAGTATGCATTTTTAATTGAAATTGTTTTACATTCTTTGTATAATAAA
CCTAAAACCAAACATGTCATAAACAAATTGACGTAAAGATATAAAATGCCAAATGAAGTATTCCAAATTTTCTATTCTAATTATTTAGCT
TCACCATCATTGTGGAAAAAAATACTAGATCCTGCTTAGTATTATATATTTTTCCTAGTGGATCAGTGAGTAATAAGTACCAAACACTAG
ACTAGAAGGTAATTTCTACATTGTTTAGAAAGGGTGAAACAATTTATCCCCTCTGGTATTGTTCTAGCATAAGCTTTAGTTATACAATGA
TTAAGATAGAAAACTTCATATATAAATTTGATAAGCAAACCCACATTTATAGCTGCAGCTAAAATATGTTTCCTTAGGGCACAGTAATCC
TTTCTGTGAATTTTGACCTTGTTTGTGTTTTTGTGAATGAAGCTATATGTCTAATCAAAAATGATTATAAAAGAGGCTCATCTCTGACAT
CATTCCAAAAATACATTCATTGATCTCTTTTTAAGAAACATCTGTTATTCACTGGGCATTGGGACTTTTTGTGAGTAATTTGAATTGAAA
TTTTATGAGCTATCCAAGAATTCTGTATGGTCTATTATTTTCAAGTCAAAATTTCCAGTAAGGATTTACTTTACATTTCATTTGGATAAA
TGAATCATTATATAGGTATGTCTTTGCTTCCATTTTGAGACATTTAGATTTTTACAGCCTGTTTCTATAGCATTTGATGTTACAACTCTA
AGCGTAGTTCAAAGACATTTAAATTGACAAGTTACCAGTTAAAGAATTTAGAATATATTAGATCCCATCTAGTATTATATATTTTTTCTA
GTTGATCATTGAGCAGTAAATACCAAATACTCGATTAGAAGGTAATTTTTACATTGTTTTGAAAGGGTGAAACAATTTATCTCCTCTGGT
ATTATTCTTAAACCACAGATAGGGATAGTAGGGTAGTGAAACGAATAAATACCTGGTAGAAGACAAGAGACTTGGGCTCTACACCTGGCT
CTGCCACTGATTTGCTAAGTCATATTGGCAATCACCACACCCTTCAGGGAATTAGTTTCATCTGTAAAATGCAGCGGTTAGTACTATAAA
ATCATACAAATTTCTTTGTGCTTTGAGAATCTATAAAGGAATGTCTGTTGATATTCTGAGTCGATTTTCATTTGCTTTTGTTCCAGAACG

>85454_85454_3_SPAG9-BRIP1_SPAG9_chr17_49133772_ENST00000357122_BRIP1_chr17_59924581_ENST00000259008_length(amino acids)=1245AA_BP=165
MELEDGVVYQEEPGGSGAVMSERVSGLAGSIYREFERLIGRYDEEVVKELMPLVVAVLENLDSVFAQDQEHQVELELLRDDNEQLITQYE
REKALRKHAEEKFIEFEDSQEQEKKDLQTRVESLESQTRQLELKAKNYADQISRLEEREAELKKEYNALHQRHTEIRKRHCFGTEVHNLD
AKVDSGKTVKLNSPLEKINSFSPQKPPGHCSRCCCSTKQGNSQESSNTIKKDHTGKSKIPKIYFGTRTHKQIAQITRELRRTAYSGVPMT
ILSSRDHTCVHPEVVGNFNRNEKCMELLDGKNGKSCYFYHGVHKISDQHTLQTFQGMCKAWDIEELVSLGKKLKACPYYTARELIQDADI
IFCPYNYLLDAQIRESMDLNLKEQVVILDEAHNIEDCARESASYSVTEVQLRFARDELDSMVNNNIRKKDHEPLRAVCCSLINWLEANAE
YLVERDYESACKIWSGNEMLLTLHKMGITTATFPILQGHFSAVLQKEEKISPIYGKEEAREVPVISASTQIMLKGLFMVLDYLFRQNSRF
ADDYKIAIQQTYSWTNQIDISDKNGLLVLPKNKKRSRQKTAVHVLNFWCLNPAVAFSDINGKVQTIVLTSGTLSPMKSFSSELGVTFTIQ
LEANHIIKNSQVWVGTIGSGPKGRNLCATFQNTETFEFQDEVGALLLSVCQTVSQGILCFLPSYKLLEKLKERWLSTGLWHNLELVKTVI
VEPQGGEKTNFDELLQVYYDAIKYKGEKDGALLVAVCRGKVSEGLDFSDDNARAVITIGIPFPNVKDLQVELKRQYNDHHSKLRGLLPGR
QWYEIQAYRALNQALGRCIRHRNDWGALILVDDRFRNNPSRYISGLSKWVRQQIQHHSTFESALESLAEFSKKHQKVLNVSIKDRTNIQD
NESTLEVTSLKYSTSPYLLEAASHLSPENFVEDEAKICVQELQCPKIITKNSPLPSSIISRKEKNDPVFLEEAGKAEKIVISRSTSPTFN
KQTKRVSWSSFNSLGQYFTGKIPKATPELGSSENSASSPPRFKTEKMESKTVLPFTDKCESSNLTVNTSFGSCPQSETIISSLKIDATLT
RKNHSEHPLCSEEALDPDIELSLVSEEDKQSTSNRDFETEAEDESIYFTPELYDPEDTDEEKNDLAETDRGNRLANNSDCILAKDLFEIR

--------------------------------------------------------------
>85454_85454_4_SPAG9-BRIP1_SPAG9_chr17_49133772_ENST00000357122_BRIP1_chr17_59924581_ENST00000577598_length(transcript)=4166nt_BP=704nt
AGTTGGTGCAGCGGCGGTTGGGGTGAGAGCGCCTACGCCACCCCTCCCCTCCTCCGGCCCCGGCCCCCACCCCGCCGGGCCCAGCCCCAG
CCCCGGCCCGGGCTCCAGCCCTAGTACCCGTCCCAGCCCGAGTCGGGTCCGTCCCGTGCGGGCAGGTGCCGCCCCTCTGCCGGCGACGCC
CCGGGCCGCCCGCCCGTCCGCTTGCCACCATGGAGCTGGAGGACGGTGTGGTGTATCAGGAGGAGCCCGGCGGCTCCGGGGCCGTGATGT
CGGAGCGGGTGTCCGGCCTGGCCGGCTCCATCTACCGCGAGTTCGAGCGGCTTATCGGGCGCTATGACGAGGAGGTGGTCAAAGAGCTGA
TGCCGCTGGTGGTGGCTGTGCTGGAGAACCTGGACTCGGTGTTCGCGCAGGACCAGGAGCACCAGGTGGAGCTGGAGCTGCTGCGGGACG
ACAACGAGCAGCTCATCACCCAGTACGAGCGGGAGAAGGCGCTGCGCAAGCACGCTGAGGAGAAATTCATTGAATTTGAAGACTCTCAAG
AACAGGAAAAAAAGGACTTACAGACCCGAGTGGAATCTTTAGAATCTCAAACAAGACAACTTGAGCTGAAAGCGAAAAACTATGCTGACC
AGATTAGCAGACTTGAAGAAAGAGAAGCAGAACTGAAGAAGGAATATAATGCATTACATCAAAGACACACTGAGATTAGAAAACGTCATT
GCTTTGGAACAGAAGTACACAATTTGGATGCAAAAGTTGATTCAGGAAAGACTGTAAAACTCAACTCTCCACTGGAAAAGATAAACTCCT
TTTCGCCACAGAAACCCCCTGGCCACTGTTCTAGGTGCTGTTGTTCTACTAAACAAGGAAACAGTCAAGAGTCATCGAATACCATTAAGA
AGGATCATACAGGGAAATCCAAGATACCCAAAATATATTTTGGGACACGCACACACAAGCAGATTGCTCAGATTACTAGAGAGCTCCGGA
GGACGGCATATTCAGGGGTTCCAATGACTATTCTTTCCAGCAGGGATCATACTTGTGTCCATCCTGAGGTAGTCGGTAACTTCAACAGAA
ATGAGAAGTGCATGGAATTGCTAGATGGGAAAAACGGAAAATCCTGCTATTTTTATCATGGAGTTCATAAAATTAGTGATCAGCACACAT
TACAGACTTTCCAAGGGATGTGCAAAGCCTGGGATATAGAAGAACTTGTCAGCCTGGGGAAGAAACTAAAGGCCTGTCCATATTACACAG
CCCGAGAACTAATACAAGATGCTGACATCATATTTTGTCCCTACAACTATCTTCTAGATGCACAAATAAGGGAAAGTATGGATTTAAATC
TGAAAGAACAGGTTGTCATTTTAGATGAAGCTCATAACATCGAGGACTGTGCTCGGGAATCAGCAAGTTACAGTGTAACAGAAGTTCAGC
TTCGGTTTGCTCGGGATGAACTAGATAGTATGGTCAACAATAATATAAGGAAGAAAGATCATGAACCCCTACGAGCTGTGTGCTGTAGCC
TCATTAATTGGTTAGAAGCAAACGCTGAATATCTTGTAGAAAGAGATTATGAATCAGCTTGTAAAATATGGAGTGGAAATGAAATGCTCT
TAACTTTACACAAAATGGGTATCACCACTGCTACTTTTCCCATTTTGCAGGGACATTTTTCTGCTGTTCTTCAAAAAGAGGAAAAAATCT
CACCAATTTATGGTAAAGAGGAGGCAAGAGAAGTACCTGTTATTAGTGCATCAACTCAAATAATGCTTAAAGGACTTTTTATGGTACTTG
ACTATCTTTTTAGGCAAAATAGCAGATTTGCAGATGATTATAAAATTGCGATTCAACAGACTTACTCCTGGACAAATCAGATTGATATTT
CAGACAAAAATGGGTTGTTGGTTCTACCAAAAAATAAGAAACGTTCACGACAGAAAACTGCAGTTCATGTGCTAAACTTTTGGTGCTTAA
ATCCAGCTGTGGCCTTTTCAGATATTAATGGCAAAGTTCAGACCATTGTTTTGACATCTGGTACATTATCACCAATGAAATCCTTTTCGT
CAGAACTTGGTGTTACATTTACTATCCAGCTGGAGGCTAATCATATCATTAAAAATTCACAGGTTTGGGTTGGTACCATTGGGTCAGGCC
CCAAGGGTCGGAATCTCTGTGCTACCTTCCAGAATACTGAAACATTTGAGTTCCAAGATGAAGTGGGAGCACTTTTGTTATCTGTGTGCC
AGACTGTGAGCCAAGGAATTTTGTGTTTCTTGCCATCTTACAAGTTATTAGAAAAATTAAAAGAACGTTGGCTCTCTACTGGTTTATGGC
ATAATCTGGAGTTGGTGAAGACAGTCATTGTAGAACCACAGGGAGGAGAAAAAACAAATTTTGATGAATTACTGCAGGTGTACTATGACG
CAATCAAATACAAAGGAGAGAAAGATGGAGCTCTCCTGGTAGCAGTTTGTCGTGGTAAAGTGAGTGAGGGTCTGGATTTCTCAGATGACA
ATGCCCGTGCTGTCATAACAATAGGAATTCCTTTTCCAAATGTGAAAGATCTACAGGTTGAACTAAAACGACAATACAATGACCACCATT
CAAAATTGAGAGGTCTTCTACCTGGCCGTCAGTGGTATGAAATTCAAGCATACAGGGCCTTAAACCAGGCCCTTGGTAGATGTATTAGAC
ACAGAAATGATTGGGGAGCTCTTATTCTAGTGGATGATCGCTTTAGGAATAACCCAAGTCGCTATATATCTGGACTTTCTAAATGGGTAC
GGCAGCAGATTCAGCACCATTCAACCTTTGAAAGTGCACTGGAATCCTTGGCTGAATTTTCCAAAAAGCATCAAAAAGTTCTTAATGTAT
CCATAAAGGACAGAACCAATATACAGGACAATGAGTCTACACTTGAAGTGACCTCTTTAAAGTACAGTACCTCACCTTATTTACTGGAAG
CAGCAAGTCATCTATCACCAGAAAATTTTGTGGAAGATGAAGCAAAGATATGTGTCCAGGAACTACAGTGTCCTAAAATTATTACCAAAA
ATTCACCTCTACCAAGTAGCATTATCTCCAGAAAGGAGAAAAGTATGAAAAGTTCTTCCCATTTACCTTTGATAGAGAAGTCTTTCATTA
TATTTAGTGAAATGATATTTATTTGGGTATAGATTAATTCCTTAAATATGGTGGTTTGTAATATAAGGTGTTATCATAAAATAGTGAAAC
AGTATGGTGTACTGTAATGGGAACAAACTTTTGTCAGGAGACCAGAGCATATTTTCTGGTTTTCCACTAACTGGCTTTGCCACTTACTAG
CTTTGTGATCATGAGCAAGTCATTTGTCCTTTTTGAGTCGTAATAGGAAAAAAAAAATGCCTGCCTAGCTATCCCTTCAGGTTGGGTTGT
AAAGGTCAAAATTATAAATATCACAGCATTGTAAAGTACCATGTAAGTGGTAGATGTTATTCTAAAGGCTATATAAAAATTTGGCCTAAT
TTTTATGTAGATACTTCTATATGAACTACTTTTCCTATATAGATAGTTCTTATGAACTTATTTTTAGGAGGTGAGAGACATTTATTTTAA
GTGATGAAAAATAATATTTTAAAATATTTTGAAATAATCATCTGTATCAGATTGGCAAACTGTGGCCCATGGGCCAAATTTGGCCTGCTG
CCTGTTTTTGTAAATAAAGTTTAATGAAATGTAGTCATGCCCATTTATTTACATTTTAGAAACAACAGCAGAGTTGAGTATTTGTGTGTA
TTGCACTAGAACAGCATAATTGAGTAGTCGCAACAGATACATTATGCTCCACAAAGCCTAAATATTACTATCTGGCCTATGACAGAAAAG
GTTTGCCAAACTCTGGTCTATTCCATTGGATATAATTTCAGTTGTTTTAATTCATATATCCAAGGCGGGTGGATCATCCGAGGTCAGGAG
TCCGAGACCAGCCTGACCAGTGTGGTGAAACACCGTCTCTACTAAAAAAATACAAAAATTAGCTGGGTGTGGAGGCAGCTGTCTGTAATC
CCAGCTACTCAGGAGGCTGAGGCAGGAGAATTGCTTGAACTGGGAGGTGGAGGTTGCAGTGAGCCAGGATTGCGCCATTGCACTCCAGCC

>85454_85454_4_SPAG9-BRIP1_SPAG9_chr17_49133772_ENST00000357122_BRIP1_chr17_59924581_ENST00000577598_length(amino acids)=990AA_BP=165
MELEDGVVYQEEPGGSGAVMSERVSGLAGSIYREFERLIGRYDEEVVKELMPLVVAVLENLDSVFAQDQEHQVELELLRDDNEQLITQYE
REKALRKHAEEKFIEFEDSQEQEKKDLQTRVESLESQTRQLELKAKNYADQISRLEEREAELKKEYNALHQRHTEIRKRHCFGTEVHNLD
AKVDSGKTVKLNSPLEKINSFSPQKPPGHCSRCCCSTKQGNSQESSNTIKKDHTGKSKIPKIYFGTRTHKQIAQITRELRRTAYSGVPMT
ILSSRDHTCVHPEVVGNFNRNEKCMELLDGKNGKSCYFYHGVHKISDQHTLQTFQGMCKAWDIEELVSLGKKLKACPYYTARELIQDADI
IFCPYNYLLDAQIRESMDLNLKEQVVILDEAHNIEDCARESASYSVTEVQLRFARDELDSMVNNNIRKKDHEPLRAVCCSLINWLEANAE
YLVERDYESACKIWSGNEMLLTLHKMGITTATFPILQGHFSAVLQKEEKISPIYGKEEAREVPVISASTQIMLKGLFMVLDYLFRQNSRF
ADDYKIAIQQTYSWTNQIDISDKNGLLVLPKNKKRSRQKTAVHVLNFWCLNPAVAFSDINGKVQTIVLTSGTLSPMKSFSSELGVTFTIQ
LEANHIIKNSQVWVGTIGSGPKGRNLCATFQNTETFEFQDEVGALLLSVCQTVSQGILCFLPSYKLLEKLKERWLSTGLWHNLELVKTVI
VEPQGGEKTNFDELLQVYYDAIKYKGEKDGALLVAVCRGKVSEGLDFSDDNARAVITIGIPFPNVKDLQVELKRQYNDHHSKLRGLLPGR
QWYEIQAYRALNQALGRCIRHRNDWGALILVDDRFRNNPSRYISGLSKWVRQQIQHHSTFESALESLAEFSKKHQKVLNVSIKDRTNIQD
NESTLEVTSLKYSTSPYLLEAASHLSPENFVEDEAKICVQELQCPKIITKNSPLPSSIISRKEKSMKSSSHLPLIEKSFIIFSEMIFIWV

--------------------------------------------------------------
>85454_85454_5_SPAG9-BRIP1_SPAG9_chr17_49133772_ENST00000505279_BRIP1_chr17_59924581_ENST00000259008_length(transcript)=5846nt_BP=573nt
GTCGGGTCCGTCCCGTGCGGGCAGGTGCCGCCCCTCTGCCGGCGACGCCCCGGGCCGCCCGCCCGTCCGCTTGCCACCATGGAGCTGGAG
GACGGTGTGGTGTATCAGGAGGAGCCCGGCGGCTCCGGGGCCGTGATGTCGGAGCGGGTGTCCGGCCTGGCCGGCTCCATCTACCGCGAG
TTCGAGCGGCTTATCGGGCGCTATGACGAGGAGGTGGTCAAAGAGCTGATGCCGCTGGTGGTGGCTGTGCTGGAGAACCTGGACTCGGTG
TTCGCGCAGGACCAGGAGCACCAGGTGGAGCTGGAGCTGCTGCGGGACGACAACGAGCAGCTCATCACCCAGTACGAGCGGGAGAAGGCG
CTGCGCAAGCACGCTGAGGAGAAATTCATTGAATTTGAAGACTCTCAAGAACAGGAAAAAAAGGACTTACAGACCCGAGTGGAATCTTTA
GAATCTCAAACAAGACAACTTGAGCTGAAAGCGAAAAACTATGCTGACCAGATTAGCAGACTTGAAGAAAGAGAAGCAGAACTGAAGAAG
GAATATAATGCATTACATCAAAGACACACTGAGATTAGAAAACGTCATTGCTTTGGAACAGAAGTACACAATTTGGATGCAAAAGTTGAT
TCAGGAAAGACTGTAAAACTCAACTCTCCACTGGAAAAGATAAACTCCTTTTCGCCACAGAAACCCCCTGGCCACTGTTCTAGGTGCTGT
TGTTCTACTAAACAAGGAAACAGTCAAGAGTCATCGAATACCATTAAGAAGGATCATACAGGGAAATCCAAGATACCCAAAATATATTTT
GGGACACGCACACACAAGCAGATTGCTCAGATTACTAGAGAGCTCCGGAGGACGGCATATTCAGGGGTTCCAATGACTATTCTTTCCAGC
AGGGATCATACTTGTGTCCATCCTGAGGTAGTCGGTAACTTCAACAGAAATGAGAAGTGCATGGAATTGCTAGATGGGAAAAACGGAAAA
TCCTGCTATTTTTATCATGGAGTTCATAAAATTAGTGATCAGCACACATTACAGACTTTCCAAGGGATGTGCAAAGCCTGGGATATAGAA
GAACTTGTCAGCCTGGGGAAGAAACTAAAGGCCTGTCCATATTACACAGCCCGAGAACTAATACAAGATGCTGACATCATATTTTGTCCC
TACAACTATCTTCTAGATGCACAAATAAGGGAAAGTATGGATTTAAATCTGAAAGAACAGGTTGTCATTTTAGATGAAGCTCATAACATC
GAGGACTGTGCTCGGGAATCAGCAAGTTACAGTGTAACAGAAGTTCAGCTTCGGTTTGCTCGGGATGAACTAGATAGTATGGTCAACAAT
AATATAAGGAAGAAAGATCATGAACCCCTACGAGCTGTGTGCTGTAGCCTCATTAATTGGTTAGAAGCAAACGCTGAATATCTTGTAGAA
AGAGATTATGAATCAGCTTGTAAAATATGGAGTGGAAATGAAATGCTCTTAACTTTACACAAAATGGGTATCACCACTGCTACTTTTCCC
ATTTTGCAGGGACATTTTTCTGCTGTTCTTCAAAAAGAGGAAAAAATCTCACCAATTTATGGTAAAGAGGAGGCAAGAGAAGTACCTGTT
ATTAGTGCATCAACTCAAATAATGCTTAAAGGACTTTTTATGGTACTTGACTATCTTTTTAGGCAAAATAGCAGATTTGCAGATGATTAT
AAAATTGCGATTCAACAGACTTACTCCTGGACAAATCAGATTGATATTTCAGACAAAAATGGGTTGTTGGTTCTACCAAAAAATAAGAAA
CGTTCACGACAGAAAACTGCAGTTCATGTGCTAAACTTTTGGTGCTTAAATCCAGCTGTGGCCTTTTCAGATATTAATGGCAAAGTTCAG
ACCATTGTTTTGACATCTGGTACATTATCACCAATGAAATCCTTTTCGTCAGAACTTGGTGTTACATTTACTATCCAGCTGGAGGCTAAT
CATATCATTAAAAATTCACAGGTTTGGGTTGGTACCATTGGGTCAGGCCCCAAGGGTCGGAATCTCTGTGCTACCTTCCAGAATACTGAA
ACATTTGAGTTCCAAGATGAAGTGGGAGCACTTTTGTTATCTGTGTGCCAGACTGTGAGCCAAGGAATTTTGTGTTTCTTGCCATCTTAC
AAGTTATTAGAAAAATTAAAAGAACGTTGGCTCTCTACTGGTTTATGGCATAATCTGGAGTTGGTGAAGACAGTCATTGTAGAACCACAG
GGAGGAGAAAAAACAAATTTTGATGAATTACTGCAGGTGTACTATGACGCAATCAAATACAAAGGAGAGAAAGATGGAGCTCTCCTGGTA
GCAGTTTGTCGTGGTAAAGTGAGTGAGGGTCTGGATTTCTCAGATGACAATGCCCGTGCTGTCATAACAATAGGAATTCCTTTTCCAAAT
GTGAAAGATCTACAGGTTGAACTAAAACGACAATACAATGACCACCATTCAAAATTGAGAGGTCTTCTACCTGGCCGTCAGTGGTATGAA
ATTCAAGCATACAGGGCCTTAAACCAGGCCCTTGGTAGATGTATTAGACACAGAAATGATTGGGGAGCTCTTATTCTAGTGGATGATCGC
TTTAGGAATAACCCAAGTCGCTATATATCTGGACTTTCTAAATGGGTACGGCAGCAGATTCAGCACCATTCAACCTTTGAAAGTGCACTG
GAATCCTTGGCTGAATTTTCCAAAAAGCATCAAAAAGTTCTTAATGTATCCATAAAGGACAGAACCAATATACAGGACAATGAGTCTACA
CTTGAAGTGACCTCTTTAAAGTACAGTACCTCACCTTATTTACTGGAAGCAGCAAGTCATCTATCACCAGAAAATTTTGTGGAAGATGAA
GCAAAGATATGTGTCCAGGAACTACAGTGTCCTAAAATTATTACCAAAAATTCACCTCTACCAAGTAGCATTATCTCCAGAAAGGAGAAA
AATGATCCAGTATTCCTGGAAGAAGCAGGGAAAGCAGAAAAAATTGTGATTTCCAGATCCACAAGCCCAACTTTCAACAAACAAACAAAG
AGAGTTAGCTGGTCAAGCTTTAATTCTTTGGGACAGTATTTTACTGGTAAAATACCGAAGGCAACACCTGAGCTCGGGTCATCAGAGAAT
AGTGCCTCTAGTCCTCCCCGTTTCAAAACAGAGAAGATGGAAAGTAAAACTGTTTTGCCCTTCACTGATAAATGTGAATCCTCAAATCTG
ACAGTAAACACATCGTTTGGATCATGCCCTCAATCAGAAACCATTATTTCATCATTAAAGATTGATGCCACCCTTACTAGAAAAAATCAT
TCTGAACATCCGCTCTGTTCTGAAGAAGCCCTGGATCCAGACATTGAATTGTCTCTAGTAAGTGAAGAAGATAAACAGTCCACTTCAAAT
AGAGATTTTGAAACAGAAGCAGAAGATGAATCTATCTATTTTACACCTGAACTTTATGATCCTGAAGATACAGATGAAGAAAAAAATGAC
CTAGCTGAAACTGATAGAGGAAATAGATTGGCTAACAATTCAGATTGCATTTTAGCTAAAGACCTTTTTGAAATTAGAACTATAAAAGAA
GTAGATTCAGCCAGAGAAGTGAAAGCTGAGGATTGCATAGATACAAAGTTGAATGGAATTCTGCATATTGAAGAAAGTAAAATTGATGAC
ATTGATGGTAATGTAAAAACAACTTGGATAAATGAACTGGAACTGGGAAAAACTCATGAAATAGAAATAAAGAACTTTAAACCATCTCCT
TCCAAAAATAAAGGCATGTTTCCTGGTTTTAAGTAATAATACTTAACTCTCAAGCTAAGTAAAAATATGTCATCATGCTTATGTTAAACT
CTGTTGTAAGTAATAATTTGTAAATTGAATAAGTGGCATACTTTTTAAAAAACTATTTTATGTTCAGAAATGTAAATGTTATTATTCTTG
AGTTTTTGGGTTTTTTTTTTTGAGACAGAGTCTTGGTCTGTTGCCCAGGCTGGAATGCAGTGGTGTGCTCTGGGCTCACTGCAACCTTCA
CCTCCAGGTTCAAGTGATTCTCCTGCCTCAGCCTTCTGAGTAGCTGGGACTACAGGTGTGCACCACCATGCCCAGCTAGTTTTTGTATTT
TTAGTAGAGATGGGGTTTCACCATGTTGGCCAGGCTGGTCTCGAACTCCTGGCCTCGTGATCTGCCCTTCTCTGCCTCCCTAAGTTGCTG
GGATTACAGGTGTGAGCCACAGTGCCTGGCCCATTCTTGAGTTTTGATAAAGTAATTCATACAAAGTACTGTCCTCAAATAAGTCTTCCT
TAGCTAAATGCAATTTAAAATTATTCAAAGATCCTAGGGCACTTCTAGTTTCACGTAAATATTCATATTAGGTGGTTCTCTTCATCCATT
TGTTTTCACACTGATACATAAAAATTAACAGCAGTCTAATCTAGTGACACCTCAGTCATATTTCGCTATAGATTTTACCTCAAATCAGTC
CAAGACTTTTTCAGAGATCACCATTTGTCTTGAAAGGTTTATTTCGTTATTAAACTGCCTACTTATAAGTAATTAAGAGAAATTAAGAAA
GTAGTATGCATTTTTAATTGAAATTGTTTTACATTCTTTGTATAATAAACCTAAAACCAAACATGTCATAAACAAATTGACGTAAAGATA
TAAAATGCCAAATGAAGTATTCCAAATTTTCTATTCTAATTATTTAGCTTCACCATCATTGTGGAAAAAAATACTAGATCCTGCTTAGTA
TTATATATTTTTCCTAGTGGATCAGTGAGTAATAAGTACCAAACACTAGACTAGAAGGTAATTTCTACATTGTTTAGAAAGGGTGAAACA
ATTTATCCCCTCTGGTATTGTTCTAGCATAAGCTTTAGTTATACAATGATTAAGATAGAAAACTTCATATATAAATTTGATAAGCAAACC
CACATTTATAGCTGCAGCTAAAATATGTTTCCTTAGGGCACAGTAATCCTTTCTGTGAATTTTGACCTTGTTTGTGTTTTTGTGAATGAA
GCTATATGTCTAATCAAAAATGATTATAAAAGAGGCTCATCTCTGACATCATTCCAAAAATACATTCATTGATCTCTTTTTAAGAAACAT
CTGTTATTCACTGGGCATTGGGACTTTTTGTGAGTAATTTGAATTGAAATTTTATGAGCTATCCAAGAATTCTGTATGGTCTATTATTTT
CAAGTCAAAATTTCCAGTAAGGATTTACTTTACATTTCATTTGGATAAATGAATCATTATATAGGTATGTCTTTGCTTCCATTTTGAGAC
ATTTAGATTTTTACAGCCTGTTTCTATAGCATTTGATGTTACAACTCTAAGCGTAGTTCAAAGACATTTAAATTGACAAGTTACCAGTTA
AAGAATTTAGAATATATTAGATCCCATCTAGTATTATATATTTTTTCTAGTTGATCATTGAGCAGTAAATACCAAATACTCGATTAGAAG
GTAATTTTTACATTGTTTTGAAAGGGTGAAACAATTTATCTCCTCTGGTATTATTCTTAAACCACAGATAGGGATAGTAGGGTAGTGAAA
CGAATAAATACCTGGTAGAAGACAAGAGACTTGGGCTCTACACCTGGCTCTGCCACTGATTTGCTAAGTCATATTGGCAATCACCACACC
CTTCAGGGAATTAGTTTCATCTGTAAAATGCAGCGGTTAGTACTATAAAATCATACAAATTTCTTTGTGCTTTGAGAATCTATAAAGGAA

>85454_85454_5_SPAG9-BRIP1_SPAG9_chr17_49133772_ENST00000505279_BRIP1_chr17_59924581_ENST00000259008_length(amino acids)=1245AA_BP=165
MELEDGVVYQEEPGGSGAVMSERVSGLAGSIYREFERLIGRYDEEVVKELMPLVVAVLENLDSVFAQDQEHQVELELLRDDNEQLITQYE
REKALRKHAEEKFIEFEDSQEQEKKDLQTRVESLESQTRQLELKAKNYADQISRLEEREAELKKEYNALHQRHTEIRKRHCFGTEVHNLD
AKVDSGKTVKLNSPLEKINSFSPQKPPGHCSRCCCSTKQGNSQESSNTIKKDHTGKSKIPKIYFGTRTHKQIAQITRELRRTAYSGVPMT
ILSSRDHTCVHPEVVGNFNRNEKCMELLDGKNGKSCYFYHGVHKISDQHTLQTFQGMCKAWDIEELVSLGKKLKACPYYTARELIQDADI
IFCPYNYLLDAQIRESMDLNLKEQVVILDEAHNIEDCARESASYSVTEVQLRFARDELDSMVNNNIRKKDHEPLRAVCCSLINWLEANAE
YLVERDYESACKIWSGNEMLLTLHKMGITTATFPILQGHFSAVLQKEEKISPIYGKEEAREVPVISASTQIMLKGLFMVLDYLFRQNSRF
ADDYKIAIQQTYSWTNQIDISDKNGLLVLPKNKKRSRQKTAVHVLNFWCLNPAVAFSDINGKVQTIVLTSGTLSPMKSFSSELGVTFTIQ
LEANHIIKNSQVWVGTIGSGPKGRNLCATFQNTETFEFQDEVGALLLSVCQTVSQGILCFLPSYKLLEKLKERWLSTGLWHNLELVKTVI
VEPQGGEKTNFDELLQVYYDAIKYKGEKDGALLVAVCRGKVSEGLDFSDDNARAVITIGIPFPNVKDLQVELKRQYNDHHSKLRGLLPGR
QWYEIQAYRALNQALGRCIRHRNDWGALILVDDRFRNNPSRYISGLSKWVRQQIQHHSTFESALESLAEFSKKHQKVLNVSIKDRTNIQD
NESTLEVTSLKYSTSPYLLEAASHLSPENFVEDEAKICVQELQCPKIITKNSPLPSSIISRKEKNDPVFLEEAGKAEKIVISRSTSPTFN
KQTKRVSWSSFNSLGQYFTGKIPKATPELGSSENSASSPPRFKTEKMESKTVLPFTDKCESSNLTVNTSFGSCPQSETIISSLKIDATLT
RKNHSEHPLCSEEALDPDIELSLVSEEDKQSTSNRDFETEAEDESIYFTPELYDPEDTDEEKNDLAETDRGNRLANNSDCILAKDLFEIR

--------------------------------------------------------------
>85454_85454_6_SPAG9-BRIP1_SPAG9_chr17_49133772_ENST00000505279_BRIP1_chr17_59924581_ENST00000577598_length(transcript)=4035nt_BP=573nt
GTCGGGTCCGTCCCGTGCGGGCAGGTGCCGCCCCTCTGCCGGCGACGCCCCGGGCCGCCCGCCCGTCCGCTTGCCACCATGGAGCTGGAG
GACGGTGTGGTGTATCAGGAGGAGCCCGGCGGCTCCGGGGCCGTGATGTCGGAGCGGGTGTCCGGCCTGGCCGGCTCCATCTACCGCGAG
TTCGAGCGGCTTATCGGGCGCTATGACGAGGAGGTGGTCAAAGAGCTGATGCCGCTGGTGGTGGCTGTGCTGGAGAACCTGGACTCGGTG
TTCGCGCAGGACCAGGAGCACCAGGTGGAGCTGGAGCTGCTGCGGGACGACAACGAGCAGCTCATCACCCAGTACGAGCGGGAGAAGGCG
CTGCGCAAGCACGCTGAGGAGAAATTCATTGAATTTGAAGACTCTCAAGAACAGGAAAAAAAGGACTTACAGACCCGAGTGGAATCTTTA
GAATCTCAAACAAGACAACTTGAGCTGAAAGCGAAAAACTATGCTGACCAGATTAGCAGACTTGAAGAAAGAGAAGCAGAACTGAAGAAG
GAATATAATGCATTACATCAAAGACACACTGAGATTAGAAAACGTCATTGCTTTGGAACAGAAGTACACAATTTGGATGCAAAAGTTGAT
TCAGGAAAGACTGTAAAACTCAACTCTCCACTGGAAAAGATAAACTCCTTTTCGCCACAGAAACCCCCTGGCCACTGTTCTAGGTGCTGT
TGTTCTACTAAACAAGGAAACAGTCAAGAGTCATCGAATACCATTAAGAAGGATCATACAGGGAAATCCAAGATACCCAAAATATATTTT
GGGACACGCACACACAAGCAGATTGCTCAGATTACTAGAGAGCTCCGGAGGACGGCATATTCAGGGGTTCCAATGACTATTCTTTCCAGC
AGGGATCATACTTGTGTCCATCCTGAGGTAGTCGGTAACTTCAACAGAAATGAGAAGTGCATGGAATTGCTAGATGGGAAAAACGGAAAA
TCCTGCTATTTTTATCATGGAGTTCATAAAATTAGTGATCAGCACACATTACAGACTTTCCAAGGGATGTGCAAAGCCTGGGATATAGAA
GAACTTGTCAGCCTGGGGAAGAAACTAAAGGCCTGTCCATATTACACAGCCCGAGAACTAATACAAGATGCTGACATCATATTTTGTCCC
TACAACTATCTTCTAGATGCACAAATAAGGGAAAGTATGGATTTAAATCTGAAAGAACAGGTTGTCATTTTAGATGAAGCTCATAACATC
GAGGACTGTGCTCGGGAATCAGCAAGTTACAGTGTAACAGAAGTTCAGCTTCGGTTTGCTCGGGATGAACTAGATAGTATGGTCAACAAT
AATATAAGGAAGAAAGATCATGAACCCCTACGAGCTGTGTGCTGTAGCCTCATTAATTGGTTAGAAGCAAACGCTGAATATCTTGTAGAA
AGAGATTATGAATCAGCTTGTAAAATATGGAGTGGAAATGAAATGCTCTTAACTTTACACAAAATGGGTATCACCACTGCTACTTTTCCC
ATTTTGCAGGGACATTTTTCTGCTGTTCTTCAAAAAGAGGAAAAAATCTCACCAATTTATGGTAAAGAGGAGGCAAGAGAAGTACCTGTT
ATTAGTGCATCAACTCAAATAATGCTTAAAGGACTTTTTATGGTACTTGACTATCTTTTTAGGCAAAATAGCAGATTTGCAGATGATTAT
AAAATTGCGATTCAACAGACTTACTCCTGGACAAATCAGATTGATATTTCAGACAAAAATGGGTTGTTGGTTCTACCAAAAAATAAGAAA
CGTTCACGACAGAAAACTGCAGTTCATGTGCTAAACTTTTGGTGCTTAAATCCAGCTGTGGCCTTTTCAGATATTAATGGCAAAGTTCAG
ACCATTGTTTTGACATCTGGTACATTATCACCAATGAAATCCTTTTCGTCAGAACTTGGTGTTACATTTACTATCCAGCTGGAGGCTAAT
CATATCATTAAAAATTCACAGGTTTGGGTTGGTACCATTGGGTCAGGCCCCAAGGGTCGGAATCTCTGTGCTACCTTCCAGAATACTGAA
ACATTTGAGTTCCAAGATGAAGTGGGAGCACTTTTGTTATCTGTGTGCCAGACTGTGAGCCAAGGAATTTTGTGTTTCTTGCCATCTTAC
AAGTTATTAGAAAAATTAAAAGAACGTTGGCTCTCTACTGGTTTATGGCATAATCTGGAGTTGGTGAAGACAGTCATTGTAGAACCACAG
GGAGGAGAAAAAACAAATTTTGATGAATTACTGCAGGTGTACTATGACGCAATCAAATACAAAGGAGAGAAAGATGGAGCTCTCCTGGTA
GCAGTTTGTCGTGGTAAAGTGAGTGAGGGTCTGGATTTCTCAGATGACAATGCCCGTGCTGTCATAACAATAGGAATTCCTTTTCCAAAT
GTGAAAGATCTACAGGTTGAACTAAAACGACAATACAATGACCACCATTCAAAATTGAGAGGTCTTCTACCTGGCCGTCAGTGGTATGAA
ATTCAAGCATACAGGGCCTTAAACCAGGCCCTTGGTAGATGTATTAGACACAGAAATGATTGGGGAGCTCTTATTCTAGTGGATGATCGC
TTTAGGAATAACCCAAGTCGCTATATATCTGGACTTTCTAAATGGGTACGGCAGCAGATTCAGCACCATTCAACCTTTGAAAGTGCACTG
GAATCCTTGGCTGAATTTTCCAAAAAGCATCAAAAAGTTCTTAATGTATCCATAAAGGACAGAACCAATATACAGGACAATGAGTCTACA
CTTGAAGTGACCTCTTTAAAGTACAGTACCTCACCTTATTTACTGGAAGCAGCAAGTCATCTATCACCAGAAAATTTTGTGGAAGATGAA
GCAAAGATATGTGTCCAGGAACTACAGTGTCCTAAAATTATTACCAAAAATTCACCTCTACCAAGTAGCATTATCTCCAGAAAGGAGAAA
AGTATGAAAAGTTCTTCCCATTTACCTTTGATAGAGAAGTCTTTCATTATATTTAGTGAAATGATATTTATTTGGGTATAGATTAATTCC
TTAAATATGGTGGTTTGTAATATAAGGTGTTATCATAAAATAGTGAAACAGTATGGTGTACTGTAATGGGAACAAACTTTTGTCAGGAGA
CCAGAGCATATTTTCTGGTTTTCCACTAACTGGCTTTGCCACTTACTAGCTTTGTGATCATGAGCAAGTCATTTGTCCTTTTTGAGTCGT
AATAGGAAAAAAAAAATGCCTGCCTAGCTATCCCTTCAGGTTGGGTTGTAAAGGTCAAAATTATAAATATCACAGCATTGTAAAGTACCA
TGTAAGTGGTAGATGTTATTCTAAAGGCTATATAAAAATTTGGCCTAATTTTTATGTAGATACTTCTATATGAACTACTTTTCCTATATA
GATAGTTCTTATGAACTTATTTTTAGGAGGTGAGAGACATTTATTTTAAGTGATGAAAAATAATATTTTAAAATATTTTGAAATAATCAT
CTGTATCAGATTGGCAAACTGTGGCCCATGGGCCAAATTTGGCCTGCTGCCTGTTTTTGTAAATAAAGTTTAATGAAATGTAGTCATGCC
CATTTATTTACATTTTAGAAACAACAGCAGAGTTGAGTATTTGTGTGTATTGCACTAGAACAGCATAATTGAGTAGTCGCAACAGATACA
TTATGCTCCACAAAGCCTAAATATTACTATCTGGCCTATGACAGAAAAGGTTTGCCAAACTCTGGTCTATTCCATTGGATATAATTTCAG
TTGTTTTAATTCATATATCCAAGGCGGGTGGATCATCCGAGGTCAGGAGTCCGAGACCAGCCTGACCAGTGTGGTGAAACACCGTCTCTA
CTAAAAAAATACAAAAATTAGCTGGGTGTGGAGGCAGCTGTCTGTAATCCCAGCTACTCAGGAGGCTGAGGCAGGAGAATTGCTTGAACT

>85454_85454_6_SPAG9-BRIP1_SPAG9_chr17_49133772_ENST00000505279_BRIP1_chr17_59924581_ENST00000577598_length(amino acids)=990AA_BP=165
MELEDGVVYQEEPGGSGAVMSERVSGLAGSIYREFERLIGRYDEEVVKELMPLVVAVLENLDSVFAQDQEHQVELELLRDDNEQLITQYE
REKALRKHAEEKFIEFEDSQEQEKKDLQTRVESLESQTRQLELKAKNYADQISRLEEREAELKKEYNALHQRHTEIRKRHCFGTEVHNLD
AKVDSGKTVKLNSPLEKINSFSPQKPPGHCSRCCCSTKQGNSQESSNTIKKDHTGKSKIPKIYFGTRTHKQIAQITRELRRTAYSGVPMT
ILSSRDHTCVHPEVVGNFNRNEKCMELLDGKNGKSCYFYHGVHKISDQHTLQTFQGMCKAWDIEELVSLGKKLKACPYYTARELIQDADI
IFCPYNYLLDAQIRESMDLNLKEQVVILDEAHNIEDCARESASYSVTEVQLRFARDELDSMVNNNIRKKDHEPLRAVCCSLINWLEANAE
YLVERDYESACKIWSGNEMLLTLHKMGITTATFPILQGHFSAVLQKEEKISPIYGKEEAREVPVISASTQIMLKGLFMVLDYLFRQNSRF
ADDYKIAIQQTYSWTNQIDISDKNGLLVLPKNKKRSRQKTAVHVLNFWCLNPAVAFSDINGKVQTIVLTSGTLSPMKSFSSELGVTFTIQ
LEANHIIKNSQVWVGTIGSGPKGRNLCATFQNTETFEFQDEVGALLLSVCQTVSQGILCFLPSYKLLEKLKERWLSTGLWHNLELVKTVI
VEPQGGEKTNFDELLQVYYDAIKYKGEKDGALLVAVCRGKVSEGLDFSDDNARAVITIGIPFPNVKDLQVELKRQYNDHHSKLRGLLPGR
QWYEIQAYRALNQALGRCIRHRNDWGALILVDDRFRNNPSRYISGLSKWVRQQIQHHSTFESALESLAEFSKKHQKVLNVSIKDRTNIQD
NESTLEVTSLKYSTSPYLLEAASHLSPENFVEDEAKICVQELQCPKIITKNSPLPSSIISRKEKSMKSSSHLPLIEKSFIIFSEMIFIWV

--------------------------------------------------------------
>85454_85454_7_SPAG9-BRIP1_SPAG9_chr17_49133773_ENST00000262013_BRIP1_chr17_59924581_ENST00000259008_length(transcript)=5977nt_BP=704nt
AGTTGGTGCAGCGGCGGTTGGGGTGAGAGCGCCTACGCCACCCCTCCCCTCCTCCGGCCCCGGCCCCCACCCCGCCGGGCCCAGCCCCAG
CCCCGGCCCGGGCTCCAGCCCTAGTACCCGTCCCAGCCCGAGTCGGGTCCGTCCCGTGCGGGCAGGTGCCGCCCCTCTGCCGGCGACGCC
CCGGGCCGCCCGCCCGTCCGCTTGCCACCATGGAGCTGGAGGACGGTGTGGTGTATCAGGAGGAGCCCGGCGGCTCCGGGGCCGTGATGT
CGGAGCGGGTGTCCGGCCTGGCCGGCTCCATCTACCGCGAGTTCGAGCGGCTTATCGGGCGCTATGACGAGGAGGTGGTCAAAGAGCTGA
TGCCGCTGGTGGTGGCTGTGCTGGAGAACCTGGACTCGGTGTTCGCGCAGGACCAGGAGCACCAGGTGGAGCTGGAGCTGCTGCGGGACG
ACAACGAGCAGCTCATCACCCAGTACGAGCGGGAGAAGGCGCTGCGCAAGCACGCTGAGGAGAAATTCATTGAATTTGAAGACTCTCAAG
AACAGGAAAAAAAGGACTTACAGACCCGAGTGGAATCTTTAGAATCTCAAACAAGACAACTTGAGCTGAAAGCGAAAAACTATGCTGACC
AGATTAGCAGACTTGAAGAAAGAGAAGCAGAACTGAAGAAGGAATATAATGCATTACATCAAAGACACACTGAGATTAGAAAACGTCATT
GCTTTGGAACAGAAGTACACAATTTGGATGCAAAAGTTGATTCAGGAAAGACTGTAAAACTCAACTCTCCACTGGAAAAGATAAACTCCT
TTTCGCCACAGAAACCCCCTGGCCACTGTTCTAGGTGCTGTTGTTCTACTAAACAAGGAAACAGTCAAGAGTCATCGAATACCATTAAGA
AGGATCATACAGGGAAATCCAAGATACCCAAAATATATTTTGGGACACGCACACACAAGCAGATTGCTCAGATTACTAGAGAGCTCCGGA
GGACGGCATATTCAGGGGTTCCAATGACTATTCTTTCCAGCAGGGATCATACTTGTGTCCATCCTGAGGTAGTCGGTAACTTCAACAGAA
ATGAGAAGTGCATGGAATTGCTAGATGGGAAAAACGGAAAATCCTGCTATTTTTATCATGGAGTTCATAAAATTAGTGATCAGCACACAT
TACAGACTTTCCAAGGGATGTGCAAAGCCTGGGATATAGAAGAACTTGTCAGCCTGGGGAAGAAACTAAAGGCCTGTCCATATTACACAG
CCCGAGAACTAATACAAGATGCTGACATCATATTTTGTCCCTACAACTATCTTCTAGATGCACAAATAAGGGAAAGTATGGATTTAAATC
TGAAAGAACAGGTTGTCATTTTAGATGAAGCTCATAACATCGAGGACTGTGCTCGGGAATCAGCAAGTTACAGTGTAACAGAAGTTCAGC
TTCGGTTTGCTCGGGATGAACTAGATAGTATGGTCAACAATAATATAAGGAAGAAAGATCATGAACCCCTACGAGCTGTGTGCTGTAGCC
TCATTAATTGGTTAGAAGCAAACGCTGAATATCTTGTAGAAAGAGATTATGAATCAGCTTGTAAAATATGGAGTGGAAATGAAATGCTCT
TAACTTTACACAAAATGGGTATCACCACTGCTACTTTTCCCATTTTGCAGGGACATTTTTCTGCTGTTCTTCAAAAAGAGGAAAAAATCT
CACCAATTTATGGTAAAGAGGAGGCAAGAGAAGTACCTGTTATTAGTGCATCAACTCAAATAATGCTTAAAGGACTTTTTATGGTACTTG
ACTATCTTTTTAGGCAAAATAGCAGATTTGCAGATGATTATAAAATTGCGATTCAACAGACTTACTCCTGGACAAATCAGATTGATATTT
CAGACAAAAATGGGTTGTTGGTTCTACCAAAAAATAAGAAACGTTCACGACAGAAAACTGCAGTTCATGTGCTAAACTTTTGGTGCTTAA
ATCCAGCTGTGGCCTTTTCAGATATTAATGGCAAAGTTCAGACCATTGTTTTGACATCTGGTACATTATCACCAATGAAATCCTTTTCGT
CAGAACTTGGTGTTACATTTACTATCCAGCTGGAGGCTAATCATATCATTAAAAATTCACAGGTTTGGGTTGGTACCATTGGGTCAGGCC
CCAAGGGTCGGAATCTCTGTGCTACCTTCCAGAATACTGAAACATTTGAGTTCCAAGATGAAGTGGGAGCACTTTTGTTATCTGTGTGCC
AGACTGTGAGCCAAGGAATTTTGTGTTTCTTGCCATCTTACAAGTTATTAGAAAAATTAAAAGAACGTTGGCTCTCTACTGGTTTATGGC
ATAATCTGGAGTTGGTGAAGACAGTCATTGTAGAACCACAGGGAGGAGAAAAAACAAATTTTGATGAATTACTGCAGGTGTACTATGACG
CAATCAAATACAAAGGAGAGAAAGATGGAGCTCTCCTGGTAGCAGTTTGTCGTGGTAAAGTGAGTGAGGGTCTGGATTTCTCAGATGACA
ATGCCCGTGCTGTCATAACAATAGGAATTCCTTTTCCAAATGTGAAAGATCTACAGGTTGAACTAAAACGACAATACAATGACCACCATT
CAAAATTGAGAGGTCTTCTACCTGGCCGTCAGTGGTATGAAATTCAAGCATACAGGGCCTTAAACCAGGCCCTTGGTAGATGTATTAGAC
ACAGAAATGATTGGGGAGCTCTTATTCTAGTGGATGATCGCTTTAGGAATAACCCAAGTCGCTATATATCTGGACTTTCTAAATGGGTAC
GGCAGCAGATTCAGCACCATTCAACCTTTGAAAGTGCACTGGAATCCTTGGCTGAATTTTCCAAAAAGCATCAAAAAGTTCTTAATGTAT
CCATAAAGGACAGAACCAATATACAGGACAATGAGTCTACACTTGAAGTGACCTCTTTAAAGTACAGTACCTCACCTTATTTACTGGAAG
CAGCAAGTCATCTATCACCAGAAAATTTTGTGGAAGATGAAGCAAAGATATGTGTCCAGGAACTACAGTGTCCTAAAATTATTACCAAAA
ATTCACCTCTACCAAGTAGCATTATCTCCAGAAAGGAGAAAAATGATCCAGTATTCCTGGAAGAAGCAGGGAAAGCAGAAAAAATTGTGA
TTTCCAGATCCACAAGCCCAACTTTCAACAAACAAACAAAGAGAGTTAGCTGGTCAAGCTTTAATTCTTTGGGACAGTATTTTACTGGTA
AAATACCGAAGGCAACACCTGAGCTCGGGTCATCAGAGAATAGTGCCTCTAGTCCTCCCCGTTTCAAAACAGAGAAGATGGAAAGTAAAA
CTGTTTTGCCCTTCACTGATAAATGTGAATCCTCAAATCTGACAGTAAACACATCGTTTGGATCATGCCCTCAATCAGAAACCATTATTT
CATCATTAAAGATTGATGCCACCCTTACTAGAAAAAATCATTCTGAACATCCGCTCTGTTCTGAAGAAGCCCTGGATCCAGACATTGAAT
TGTCTCTAGTAAGTGAAGAAGATAAACAGTCCACTTCAAATAGAGATTTTGAAACAGAAGCAGAAGATGAATCTATCTATTTTACACCTG
AACTTTATGATCCTGAAGATACAGATGAAGAAAAAAATGACCTAGCTGAAACTGATAGAGGAAATAGATTGGCTAACAATTCAGATTGCA
TTTTAGCTAAAGACCTTTTTGAAATTAGAACTATAAAAGAAGTAGATTCAGCCAGAGAAGTGAAAGCTGAGGATTGCATAGATACAAAGT
TGAATGGAATTCTGCATATTGAAGAAAGTAAAATTGATGACATTGATGGTAATGTAAAAACAACTTGGATAAATGAACTGGAACTGGGAA
AAACTCATGAAATAGAAATAAAGAACTTTAAACCATCTCCTTCCAAAAATAAAGGCATGTTTCCTGGTTTTAAGTAATAATACTTAACTC
TCAAGCTAAGTAAAAATATGTCATCATGCTTATGTTAAACTCTGTTGTAAGTAATAATTTGTAAATTGAATAAGTGGCATACTTTTTAAA
AAACTATTTTATGTTCAGAAATGTAAATGTTATTATTCTTGAGTTTTTGGGTTTTTTTTTTTGAGACAGAGTCTTGGTCTGTTGCCCAGG
CTGGAATGCAGTGGTGTGCTCTGGGCTCACTGCAACCTTCACCTCCAGGTTCAAGTGATTCTCCTGCCTCAGCCTTCTGAGTAGCTGGGA
CTACAGGTGTGCACCACCATGCCCAGCTAGTTTTTGTATTTTTAGTAGAGATGGGGTTTCACCATGTTGGCCAGGCTGGTCTCGAACTCC
TGGCCTCGTGATCTGCCCTTCTCTGCCTCCCTAAGTTGCTGGGATTACAGGTGTGAGCCACAGTGCCTGGCCCATTCTTGAGTTTTGATA
AAGTAATTCATACAAAGTACTGTCCTCAAATAAGTCTTCCTTAGCTAAATGCAATTTAAAATTATTCAAAGATCCTAGGGCACTTCTAGT
TTCACGTAAATATTCATATTAGGTGGTTCTCTTCATCCATTTGTTTTCACACTGATACATAAAAATTAACAGCAGTCTAATCTAGTGACA
CCTCAGTCATATTTCGCTATAGATTTTACCTCAAATCAGTCCAAGACTTTTTCAGAGATCACCATTTGTCTTGAAAGGTTTATTTCGTTA
TTAAACTGCCTACTTATAAGTAATTAAGAGAAATTAAGAAAGTAGTATGCATTTTTAATTGAAATTGTTTTACATTCTTTGTATAATAAA
CCTAAAACCAAACATGTCATAAACAAATTGACGTAAAGATATAAAATGCCAAATGAAGTATTCCAAATTTTCTATTCTAATTATTTAGCT
TCACCATCATTGTGGAAAAAAATACTAGATCCTGCTTAGTATTATATATTTTTCCTAGTGGATCAGTGAGTAATAAGTACCAAACACTAG
ACTAGAAGGTAATTTCTACATTGTTTAGAAAGGGTGAAACAATTTATCCCCTCTGGTATTGTTCTAGCATAAGCTTTAGTTATACAATGA
TTAAGATAGAAAACTTCATATATAAATTTGATAAGCAAACCCACATTTATAGCTGCAGCTAAAATATGTTTCCTTAGGGCACAGTAATCC
TTTCTGTGAATTTTGACCTTGTTTGTGTTTTTGTGAATGAAGCTATATGTCTAATCAAAAATGATTATAAAAGAGGCTCATCTCTGACAT
CATTCCAAAAATACATTCATTGATCTCTTTTTAAGAAACATCTGTTATTCACTGGGCATTGGGACTTTTTGTGAGTAATTTGAATTGAAA
TTTTATGAGCTATCCAAGAATTCTGTATGGTCTATTATTTTCAAGTCAAAATTTCCAGTAAGGATTTACTTTACATTTCATTTGGATAAA
TGAATCATTATATAGGTATGTCTTTGCTTCCATTTTGAGACATTTAGATTTTTACAGCCTGTTTCTATAGCATTTGATGTTACAACTCTA
AGCGTAGTTCAAAGACATTTAAATTGACAAGTTACCAGTTAAAGAATTTAGAATATATTAGATCCCATCTAGTATTATATATTTTTTCTA
GTTGATCATTGAGCAGTAAATACCAAATACTCGATTAGAAGGTAATTTTTACATTGTTTTGAAAGGGTGAAACAATTTATCTCCTCTGGT
ATTATTCTTAAACCACAGATAGGGATAGTAGGGTAGTGAAACGAATAAATACCTGGTAGAAGACAAGAGACTTGGGCTCTACACCTGGCT
CTGCCACTGATTTGCTAAGTCATATTGGCAATCACCACACCCTTCAGGGAATTAGTTTCATCTGTAAAATGCAGCGGTTAGTACTATAAA
ATCATACAAATTTCTTTGTGCTTTGAGAATCTATAAAGGAATGTCTGTTGATATTCTGAGTCGATTTTCATTTGCTTTTGTTCCAGAACG

>85454_85454_7_SPAG9-BRIP1_SPAG9_chr17_49133773_ENST00000262013_BRIP1_chr17_59924581_ENST00000259008_length(amino acids)=1245AA_BP=165
MELEDGVVYQEEPGGSGAVMSERVSGLAGSIYREFERLIGRYDEEVVKELMPLVVAVLENLDSVFAQDQEHQVELELLRDDNEQLITQYE
REKALRKHAEEKFIEFEDSQEQEKKDLQTRVESLESQTRQLELKAKNYADQISRLEEREAELKKEYNALHQRHTEIRKRHCFGTEVHNLD
AKVDSGKTVKLNSPLEKINSFSPQKPPGHCSRCCCSTKQGNSQESSNTIKKDHTGKSKIPKIYFGTRTHKQIAQITRELRRTAYSGVPMT
ILSSRDHTCVHPEVVGNFNRNEKCMELLDGKNGKSCYFYHGVHKISDQHTLQTFQGMCKAWDIEELVSLGKKLKACPYYTARELIQDADI
IFCPYNYLLDAQIRESMDLNLKEQVVILDEAHNIEDCARESASYSVTEVQLRFARDELDSMVNNNIRKKDHEPLRAVCCSLINWLEANAE
YLVERDYESACKIWSGNEMLLTLHKMGITTATFPILQGHFSAVLQKEEKISPIYGKEEAREVPVISASTQIMLKGLFMVLDYLFRQNSRF
ADDYKIAIQQTYSWTNQIDISDKNGLLVLPKNKKRSRQKTAVHVLNFWCLNPAVAFSDINGKVQTIVLTSGTLSPMKSFSSELGVTFTIQ
LEANHIIKNSQVWVGTIGSGPKGRNLCATFQNTETFEFQDEVGALLLSVCQTVSQGILCFLPSYKLLEKLKERWLSTGLWHNLELVKTVI
VEPQGGEKTNFDELLQVYYDAIKYKGEKDGALLVAVCRGKVSEGLDFSDDNARAVITIGIPFPNVKDLQVELKRQYNDHHSKLRGLLPGR
QWYEIQAYRALNQALGRCIRHRNDWGALILVDDRFRNNPSRYISGLSKWVRQQIQHHSTFESALESLAEFSKKHQKVLNVSIKDRTNIQD
NESTLEVTSLKYSTSPYLLEAASHLSPENFVEDEAKICVQELQCPKIITKNSPLPSSIISRKEKNDPVFLEEAGKAEKIVISRSTSPTFN
KQTKRVSWSSFNSLGQYFTGKIPKATPELGSSENSASSPPRFKTEKMESKTVLPFTDKCESSNLTVNTSFGSCPQSETIISSLKIDATLT
RKNHSEHPLCSEEALDPDIELSLVSEEDKQSTSNRDFETEAEDESIYFTPELYDPEDTDEEKNDLAETDRGNRLANNSDCILAKDLFEIR

--------------------------------------------------------------
>85454_85454_8_SPAG9-BRIP1_SPAG9_chr17_49133773_ENST00000262013_BRIP1_chr17_59924581_ENST00000577598_length(transcript)=4166nt_BP=704nt
AGTTGGTGCAGCGGCGGTTGGGGTGAGAGCGCCTACGCCACCCCTCCCCTCCTCCGGCCCCGGCCCCCACCCCGCCGGGCCCAGCCCCAG
CCCCGGCCCGGGCTCCAGCCCTAGTACCCGTCCCAGCCCGAGTCGGGTCCGTCCCGTGCGGGCAGGTGCCGCCCCTCTGCCGGCGACGCC
CCGGGCCGCCCGCCCGTCCGCTTGCCACCATGGAGCTGGAGGACGGTGTGGTGTATCAGGAGGAGCCCGGCGGCTCCGGGGCCGTGATGT
CGGAGCGGGTGTCCGGCCTGGCCGGCTCCATCTACCGCGAGTTCGAGCGGCTTATCGGGCGCTATGACGAGGAGGTGGTCAAAGAGCTGA
TGCCGCTGGTGGTGGCTGTGCTGGAGAACCTGGACTCGGTGTTCGCGCAGGACCAGGAGCACCAGGTGGAGCTGGAGCTGCTGCGGGACG
ACAACGAGCAGCTCATCACCCAGTACGAGCGGGAGAAGGCGCTGCGCAAGCACGCTGAGGAGAAATTCATTGAATTTGAAGACTCTCAAG
AACAGGAAAAAAAGGACTTACAGACCCGAGTGGAATCTTTAGAATCTCAAACAAGACAACTTGAGCTGAAAGCGAAAAACTATGCTGACC
AGATTAGCAGACTTGAAGAAAGAGAAGCAGAACTGAAGAAGGAATATAATGCATTACATCAAAGACACACTGAGATTAGAAAACGTCATT
GCTTTGGAACAGAAGTACACAATTTGGATGCAAAAGTTGATTCAGGAAAGACTGTAAAACTCAACTCTCCACTGGAAAAGATAAACTCCT
TTTCGCCACAGAAACCCCCTGGCCACTGTTCTAGGTGCTGTTGTTCTACTAAACAAGGAAACAGTCAAGAGTCATCGAATACCATTAAGA
AGGATCATACAGGGAAATCCAAGATACCCAAAATATATTTTGGGACACGCACACACAAGCAGATTGCTCAGATTACTAGAGAGCTCCGGA
GGACGGCATATTCAGGGGTTCCAATGACTATTCTTTCCAGCAGGGATCATACTTGTGTCCATCCTGAGGTAGTCGGTAACTTCAACAGAA
ATGAGAAGTGCATGGAATTGCTAGATGGGAAAAACGGAAAATCCTGCTATTTTTATCATGGAGTTCATAAAATTAGTGATCAGCACACAT
TACAGACTTTCCAAGGGATGTGCAAAGCCTGGGATATAGAAGAACTTGTCAGCCTGGGGAAGAAACTAAAGGCCTGTCCATATTACACAG
CCCGAGAACTAATACAAGATGCTGACATCATATTTTGTCCCTACAACTATCTTCTAGATGCACAAATAAGGGAAAGTATGGATTTAAATC
TGAAAGAACAGGTTGTCATTTTAGATGAAGCTCATAACATCGAGGACTGTGCTCGGGAATCAGCAAGTTACAGTGTAACAGAAGTTCAGC
TTCGGTTTGCTCGGGATGAACTAGATAGTATGGTCAACAATAATATAAGGAAGAAAGATCATGAACCCCTACGAGCTGTGTGCTGTAGCC
TCATTAATTGGTTAGAAGCAAACGCTGAATATCTTGTAGAAAGAGATTATGAATCAGCTTGTAAAATATGGAGTGGAAATGAAATGCTCT
TAACTTTACACAAAATGGGTATCACCACTGCTACTTTTCCCATTTTGCAGGGACATTTTTCTGCTGTTCTTCAAAAAGAGGAAAAAATCT
CACCAATTTATGGTAAAGAGGAGGCAAGAGAAGTACCTGTTATTAGTGCATCAACTCAAATAATGCTTAAAGGACTTTTTATGGTACTTG
ACTATCTTTTTAGGCAAAATAGCAGATTTGCAGATGATTATAAAATTGCGATTCAACAGACTTACTCCTGGACAAATCAGATTGATATTT
CAGACAAAAATGGGTTGTTGGTTCTACCAAAAAATAAGAAACGTTCACGACAGAAAACTGCAGTTCATGTGCTAAACTTTTGGTGCTTAA
ATCCAGCTGTGGCCTTTTCAGATATTAATGGCAAAGTTCAGACCATTGTTTTGACATCTGGTACATTATCACCAATGAAATCCTTTTCGT
CAGAACTTGGTGTTACATTTACTATCCAGCTGGAGGCTAATCATATCATTAAAAATTCACAGGTTTGGGTTGGTACCATTGGGTCAGGCC
CCAAGGGTCGGAATCTCTGTGCTACCTTCCAGAATACTGAAACATTTGAGTTCCAAGATGAAGTGGGAGCACTTTTGTTATCTGTGTGCC
AGACTGTGAGCCAAGGAATTTTGTGTTTCTTGCCATCTTACAAGTTATTAGAAAAATTAAAAGAACGTTGGCTCTCTACTGGTTTATGGC
ATAATCTGGAGTTGGTGAAGACAGTCATTGTAGAACCACAGGGAGGAGAAAAAACAAATTTTGATGAATTACTGCAGGTGTACTATGACG
CAATCAAATACAAAGGAGAGAAAGATGGAGCTCTCCTGGTAGCAGTTTGTCGTGGTAAAGTGAGTGAGGGTCTGGATTTCTCAGATGACA
ATGCCCGTGCTGTCATAACAATAGGAATTCCTTTTCCAAATGTGAAAGATCTACAGGTTGAACTAAAACGACAATACAATGACCACCATT
CAAAATTGAGAGGTCTTCTACCTGGCCGTCAGTGGTATGAAATTCAAGCATACAGGGCCTTAAACCAGGCCCTTGGTAGATGTATTAGAC
ACAGAAATGATTGGGGAGCTCTTATTCTAGTGGATGATCGCTTTAGGAATAACCCAAGTCGCTATATATCTGGACTTTCTAAATGGGTAC
GGCAGCAGATTCAGCACCATTCAACCTTTGAAAGTGCACTGGAATCCTTGGCTGAATTTTCCAAAAAGCATCAAAAAGTTCTTAATGTAT
CCATAAAGGACAGAACCAATATACAGGACAATGAGTCTACACTTGAAGTGACCTCTTTAAAGTACAGTACCTCACCTTATTTACTGGAAG
CAGCAAGTCATCTATCACCAGAAAATTTTGTGGAAGATGAAGCAAAGATATGTGTCCAGGAACTACAGTGTCCTAAAATTATTACCAAAA
ATTCACCTCTACCAAGTAGCATTATCTCCAGAAAGGAGAAAAGTATGAAAAGTTCTTCCCATTTACCTTTGATAGAGAAGTCTTTCATTA
TATTTAGTGAAATGATATTTATTTGGGTATAGATTAATTCCTTAAATATGGTGGTTTGTAATATAAGGTGTTATCATAAAATAGTGAAAC
AGTATGGTGTACTGTAATGGGAACAAACTTTTGTCAGGAGACCAGAGCATATTTTCTGGTTTTCCACTAACTGGCTTTGCCACTTACTAG
CTTTGTGATCATGAGCAAGTCATTTGTCCTTTTTGAGTCGTAATAGGAAAAAAAAAATGCCTGCCTAGCTATCCCTTCAGGTTGGGTTGT
AAAGGTCAAAATTATAAATATCACAGCATTGTAAAGTACCATGTAAGTGGTAGATGTTATTCTAAAGGCTATATAAAAATTTGGCCTAAT
TTTTATGTAGATACTTCTATATGAACTACTTTTCCTATATAGATAGTTCTTATGAACTTATTTTTAGGAGGTGAGAGACATTTATTTTAA
GTGATGAAAAATAATATTTTAAAATATTTTGAAATAATCATCTGTATCAGATTGGCAAACTGTGGCCCATGGGCCAAATTTGGCCTGCTG
CCTGTTTTTGTAAATAAAGTTTAATGAAATGTAGTCATGCCCATTTATTTACATTTTAGAAACAACAGCAGAGTTGAGTATTTGTGTGTA
TTGCACTAGAACAGCATAATTGAGTAGTCGCAACAGATACATTATGCTCCACAAAGCCTAAATATTACTATCTGGCCTATGACAGAAAAG
GTTTGCCAAACTCTGGTCTATTCCATTGGATATAATTTCAGTTGTTTTAATTCATATATCCAAGGCGGGTGGATCATCCGAGGTCAGGAG
TCCGAGACCAGCCTGACCAGTGTGGTGAAACACCGTCTCTACTAAAAAAATACAAAAATTAGCTGGGTGTGGAGGCAGCTGTCTGTAATC
CCAGCTACTCAGGAGGCTGAGGCAGGAGAATTGCTTGAACTGGGAGGTGGAGGTTGCAGTGAGCCAGGATTGCGCCATTGCACTCCAGCC

>85454_85454_8_SPAG9-BRIP1_SPAG9_chr17_49133773_ENST00000262013_BRIP1_chr17_59924581_ENST00000577598_length(amino acids)=990AA_BP=165
MELEDGVVYQEEPGGSGAVMSERVSGLAGSIYREFERLIGRYDEEVVKELMPLVVAVLENLDSVFAQDQEHQVELELLRDDNEQLITQYE
REKALRKHAEEKFIEFEDSQEQEKKDLQTRVESLESQTRQLELKAKNYADQISRLEEREAELKKEYNALHQRHTEIRKRHCFGTEVHNLD
AKVDSGKTVKLNSPLEKINSFSPQKPPGHCSRCCCSTKQGNSQESSNTIKKDHTGKSKIPKIYFGTRTHKQIAQITRELRRTAYSGVPMT
ILSSRDHTCVHPEVVGNFNRNEKCMELLDGKNGKSCYFYHGVHKISDQHTLQTFQGMCKAWDIEELVSLGKKLKACPYYTARELIQDADI
IFCPYNYLLDAQIRESMDLNLKEQVVILDEAHNIEDCARESASYSVTEVQLRFARDELDSMVNNNIRKKDHEPLRAVCCSLINWLEANAE
YLVERDYESACKIWSGNEMLLTLHKMGITTATFPILQGHFSAVLQKEEKISPIYGKEEAREVPVISASTQIMLKGLFMVLDYLFRQNSRF
ADDYKIAIQQTYSWTNQIDISDKNGLLVLPKNKKRSRQKTAVHVLNFWCLNPAVAFSDINGKVQTIVLTSGTLSPMKSFSSELGVTFTIQ
LEANHIIKNSQVWVGTIGSGPKGRNLCATFQNTETFEFQDEVGALLLSVCQTVSQGILCFLPSYKLLEKLKERWLSTGLWHNLELVKTVI
VEPQGGEKTNFDELLQVYYDAIKYKGEKDGALLVAVCRGKVSEGLDFSDDNARAVITIGIPFPNVKDLQVELKRQYNDHHSKLRGLLPGR
QWYEIQAYRALNQALGRCIRHRNDWGALILVDDRFRNNPSRYISGLSKWVRQQIQHHSTFESALESLAEFSKKHQKVLNVSIKDRTNIQD
NESTLEVTSLKYSTSPYLLEAASHLSPENFVEDEAKICVQELQCPKIITKNSPLPSSIISRKEKSMKSSSHLPLIEKSFIIFSEMIFIWV

--------------------------------------------------------------
>85454_85454_9_SPAG9-BRIP1_SPAG9_chr17_49133773_ENST00000357122_BRIP1_chr17_59924581_ENST00000259008_length(transcript)=5977nt_BP=704nt
AGTTGGTGCAGCGGCGGTTGGGGTGAGAGCGCCTACGCCACCCCTCCCCTCCTCCGGCCCCGGCCCCCACCCCGCCGGGCCCAGCCCCAG
CCCCGGCCCGGGCTCCAGCCCTAGTACCCGTCCCAGCCCGAGTCGGGTCCGTCCCGTGCGGGCAGGTGCCGCCCCTCTGCCGGCGACGCC
CCGGGCCGCCCGCCCGTCCGCTTGCCACCATGGAGCTGGAGGACGGTGTGGTGTATCAGGAGGAGCCCGGCGGCTCCGGGGCCGTGATGT
CGGAGCGGGTGTCCGGCCTGGCCGGCTCCATCTACCGCGAGTTCGAGCGGCTTATCGGGCGCTATGACGAGGAGGTGGTCAAAGAGCTGA
TGCCGCTGGTGGTGGCTGTGCTGGAGAACCTGGACTCGGTGTTCGCGCAGGACCAGGAGCACCAGGTGGAGCTGGAGCTGCTGCGGGACG
ACAACGAGCAGCTCATCACCCAGTACGAGCGGGAGAAGGCGCTGCGCAAGCACGCTGAGGAGAAATTCATTGAATTTGAAGACTCTCAAG
AACAGGAAAAAAAGGACTTACAGACCCGAGTGGAATCTTTAGAATCTCAAACAAGACAACTTGAGCTGAAAGCGAAAAACTATGCTGACC
AGATTAGCAGACTTGAAGAAAGAGAAGCAGAACTGAAGAAGGAATATAATGCATTACATCAAAGACACACTGAGATTAGAAAACGTCATT
GCTTTGGAACAGAAGTACACAATTTGGATGCAAAAGTTGATTCAGGAAAGACTGTAAAACTCAACTCTCCACTGGAAAAGATAAACTCCT
TTTCGCCACAGAAACCCCCTGGCCACTGTTCTAGGTGCTGTTGTTCTACTAAACAAGGAAACAGTCAAGAGTCATCGAATACCATTAAGA
AGGATCATACAGGGAAATCCAAGATACCCAAAATATATTTTGGGACACGCACACACAAGCAGATTGCTCAGATTACTAGAGAGCTCCGGA
GGACGGCATATTCAGGGGTTCCAATGACTATTCTTTCCAGCAGGGATCATACTTGTGTCCATCCTGAGGTAGTCGGTAACTTCAACAGAA
ATGAGAAGTGCATGGAATTGCTAGATGGGAAAAACGGAAAATCCTGCTATTTTTATCATGGAGTTCATAAAATTAGTGATCAGCACACAT
TACAGACTTTCCAAGGGATGTGCAAAGCCTGGGATATAGAAGAACTTGTCAGCCTGGGGAAGAAACTAAAGGCCTGTCCATATTACACAG
CCCGAGAACTAATACAAGATGCTGACATCATATTTTGTCCCTACAACTATCTTCTAGATGCACAAATAAGGGAAAGTATGGATTTAAATC
TGAAAGAACAGGTTGTCATTTTAGATGAAGCTCATAACATCGAGGACTGTGCTCGGGAATCAGCAAGTTACAGTGTAACAGAAGTTCAGC
TTCGGTTTGCTCGGGATGAACTAGATAGTATGGTCAACAATAATATAAGGAAGAAAGATCATGAACCCCTACGAGCTGTGTGCTGTAGCC
TCATTAATTGGTTAGAAGCAAACGCTGAATATCTTGTAGAAAGAGATTATGAATCAGCTTGTAAAATATGGAGTGGAAATGAAATGCTCT
TAACTTTACACAAAATGGGTATCACCACTGCTACTTTTCCCATTTTGCAGGGACATTTTTCTGCTGTTCTTCAAAAAGAGGAAAAAATCT
CACCAATTTATGGTAAAGAGGAGGCAAGAGAAGTACCTGTTATTAGTGCATCAACTCAAATAATGCTTAAAGGACTTTTTATGGTACTTG
ACTATCTTTTTAGGCAAAATAGCAGATTTGCAGATGATTATAAAATTGCGATTCAACAGACTTACTCCTGGACAAATCAGATTGATATTT
CAGACAAAAATGGGTTGTTGGTTCTACCAAAAAATAAGAAACGTTCACGACAGAAAACTGCAGTTCATGTGCTAAACTTTTGGTGCTTAA
ATCCAGCTGTGGCCTTTTCAGATATTAATGGCAAAGTTCAGACCATTGTTTTGACATCTGGTACATTATCACCAATGAAATCCTTTTCGT
CAGAACTTGGTGTTACATTTACTATCCAGCTGGAGGCTAATCATATCATTAAAAATTCACAGGTTTGGGTTGGTACCATTGGGTCAGGCC
CCAAGGGTCGGAATCTCTGTGCTACCTTCCAGAATACTGAAACATTTGAGTTCCAAGATGAAGTGGGAGCACTTTTGTTATCTGTGTGCC
AGACTGTGAGCCAAGGAATTTTGTGTTTCTTGCCATCTTACAAGTTATTAGAAAAATTAAAAGAACGTTGGCTCTCTACTGGTTTATGGC
ATAATCTGGAGTTGGTGAAGACAGTCATTGTAGAACCACAGGGAGGAGAAAAAACAAATTTTGATGAATTACTGCAGGTGTACTATGACG
CAATCAAATACAAAGGAGAGAAAGATGGAGCTCTCCTGGTAGCAGTTTGTCGTGGTAAAGTGAGTGAGGGTCTGGATTTCTCAGATGACA
ATGCCCGTGCTGTCATAACAATAGGAATTCCTTTTCCAAATGTGAAAGATCTACAGGTTGAACTAAAACGACAATACAATGACCACCATT
CAAAATTGAGAGGTCTTCTACCTGGCCGTCAGTGGTATGAAATTCAAGCATACAGGGCCTTAAACCAGGCCCTTGGTAGATGTATTAGAC
ACAGAAATGATTGGGGAGCTCTTATTCTAGTGGATGATCGCTTTAGGAATAACCCAAGTCGCTATATATCTGGACTTTCTAAATGGGTAC
GGCAGCAGATTCAGCACCATTCAACCTTTGAAAGTGCACTGGAATCCTTGGCTGAATTTTCCAAAAAGCATCAAAAAGTTCTTAATGTAT
CCATAAAGGACAGAACCAATATACAGGACAATGAGTCTACACTTGAAGTGACCTCTTTAAAGTACAGTACCTCACCTTATTTACTGGAAG
CAGCAAGTCATCTATCACCAGAAAATTTTGTGGAAGATGAAGCAAAGATATGTGTCCAGGAACTACAGTGTCCTAAAATTATTACCAAAA
ATTCACCTCTACCAAGTAGCATTATCTCCAGAAAGGAGAAAAATGATCCAGTATTCCTGGAAGAAGCAGGGAAAGCAGAAAAAATTGTGA
TTTCCAGATCCACAAGCCCAACTTTCAACAAACAAACAAAGAGAGTTAGCTGGTCAAGCTTTAATTCTTTGGGACAGTATTTTACTGGTA
AAATACCGAAGGCAACACCTGAGCTCGGGTCATCAGAGAATAGTGCCTCTAGTCCTCCCCGTTTCAAAACAGAGAAGATGGAAAGTAAAA
CTGTTTTGCCCTTCACTGATAAATGTGAATCCTCAAATCTGACAGTAAACACATCGTTTGGATCATGCCCTCAATCAGAAACCATTATTT
CATCATTAAAGATTGATGCCACCCTTACTAGAAAAAATCATTCTGAACATCCGCTCTGTTCTGAAGAAGCCCTGGATCCAGACATTGAAT
TGTCTCTAGTAAGTGAAGAAGATAAACAGTCCACTTCAAATAGAGATTTTGAAACAGAAGCAGAAGATGAATCTATCTATTTTACACCTG
AACTTTATGATCCTGAAGATACAGATGAAGAAAAAAATGACCTAGCTGAAACTGATAGAGGAAATAGATTGGCTAACAATTCAGATTGCA
TTTTAGCTAAAGACCTTTTTGAAATTAGAACTATAAAAGAAGTAGATTCAGCCAGAGAAGTGAAAGCTGAGGATTGCATAGATACAAAGT
TGAATGGAATTCTGCATATTGAAGAAAGTAAAATTGATGACATTGATGGTAATGTAAAAACAACTTGGATAAATGAACTGGAACTGGGAA
AAACTCATGAAATAGAAATAAAGAACTTTAAACCATCTCCTTCCAAAAATAAAGGCATGTTTCCTGGTTTTAAGTAATAATACTTAACTC
TCAAGCTAAGTAAAAATATGTCATCATGCTTATGTTAAACTCTGTTGTAAGTAATAATTTGTAAATTGAATAAGTGGCATACTTTTTAAA
AAACTATTTTATGTTCAGAAATGTAAATGTTATTATTCTTGAGTTTTTGGGTTTTTTTTTTTGAGACAGAGTCTTGGTCTGTTGCCCAGG
CTGGAATGCAGTGGTGTGCTCTGGGCTCACTGCAACCTTCACCTCCAGGTTCAAGTGATTCTCCTGCCTCAGCCTTCTGAGTAGCTGGGA
CTACAGGTGTGCACCACCATGCCCAGCTAGTTTTTGTATTTTTAGTAGAGATGGGGTTTCACCATGTTGGCCAGGCTGGTCTCGAACTCC
TGGCCTCGTGATCTGCCCTTCTCTGCCTCCCTAAGTTGCTGGGATTACAGGTGTGAGCCACAGTGCCTGGCCCATTCTTGAGTTTTGATA
AAGTAATTCATACAAAGTACTGTCCTCAAATAAGTCTTCCTTAGCTAAATGCAATTTAAAATTATTCAAAGATCCTAGGGCACTTCTAGT
TTCACGTAAATATTCATATTAGGTGGTTCTCTTCATCCATTTGTTTTCACACTGATACATAAAAATTAACAGCAGTCTAATCTAGTGACA
CCTCAGTCATATTTCGCTATAGATTTTACCTCAAATCAGTCCAAGACTTTTTCAGAGATCACCATTTGTCTTGAAAGGTTTATTTCGTTA
TTAAACTGCCTACTTATAAGTAATTAAGAGAAATTAAGAAAGTAGTATGCATTTTTAATTGAAATTGTTTTACATTCTTTGTATAATAAA
CCTAAAACCAAACATGTCATAAACAAATTGACGTAAAGATATAAAATGCCAAATGAAGTATTCCAAATTTTCTATTCTAATTATTTAGCT
TCACCATCATTGTGGAAAAAAATACTAGATCCTGCTTAGTATTATATATTTTTCCTAGTGGATCAGTGAGTAATAAGTACCAAACACTAG
ACTAGAAGGTAATTTCTACATTGTTTAGAAAGGGTGAAACAATTTATCCCCTCTGGTATTGTTCTAGCATAAGCTTTAGTTATACAATGA
TTAAGATAGAAAACTTCATATATAAATTTGATAAGCAAACCCACATTTATAGCTGCAGCTAAAATATGTTTCCTTAGGGCACAGTAATCC
TTTCTGTGAATTTTGACCTTGTTTGTGTTTTTGTGAATGAAGCTATATGTCTAATCAAAAATGATTATAAAAGAGGCTCATCTCTGACAT
CATTCCAAAAATACATTCATTGATCTCTTTTTAAGAAACATCTGTTATTCACTGGGCATTGGGACTTTTTGTGAGTAATTTGAATTGAAA
TTTTATGAGCTATCCAAGAATTCTGTATGGTCTATTATTTTCAAGTCAAAATTTCCAGTAAGGATTTACTTTACATTTCATTTGGATAAA
TGAATCATTATATAGGTATGTCTTTGCTTCCATTTTGAGACATTTAGATTTTTACAGCCTGTTTCTATAGCATTTGATGTTACAACTCTA
AGCGTAGTTCAAAGACATTTAAATTGACAAGTTACCAGTTAAAGAATTTAGAATATATTAGATCCCATCTAGTATTATATATTTTTTCTA
GTTGATCATTGAGCAGTAAATACCAAATACTCGATTAGAAGGTAATTTTTACATTGTTTTGAAAGGGTGAAACAATTTATCTCCTCTGGT
ATTATTCTTAAACCACAGATAGGGATAGTAGGGTAGTGAAACGAATAAATACCTGGTAGAAGACAAGAGACTTGGGCTCTACACCTGGCT
CTGCCACTGATTTGCTAAGTCATATTGGCAATCACCACACCCTTCAGGGAATTAGTTTCATCTGTAAAATGCAGCGGTTAGTACTATAAA
ATCATACAAATTTCTTTGTGCTTTGAGAATCTATAAAGGAATGTCTGTTGATATTCTGAGTCGATTTTCATTTGCTTTTGTTCCAGAACG

>85454_85454_9_SPAG9-BRIP1_SPAG9_chr17_49133773_ENST00000357122_BRIP1_chr17_59924581_ENST00000259008_length(amino acids)=1245AA_BP=165
MELEDGVVYQEEPGGSGAVMSERVSGLAGSIYREFERLIGRYDEEVVKELMPLVVAVLENLDSVFAQDQEHQVELELLRDDNEQLITQYE
REKALRKHAEEKFIEFEDSQEQEKKDLQTRVESLESQTRQLELKAKNYADQISRLEEREAELKKEYNALHQRHTEIRKRHCFGTEVHNLD
AKVDSGKTVKLNSPLEKINSFSPQKPPGHCSRCCCSTKQGNSQESSNTIKKDHTGKSKIPKIYFGTRTHKQIAQITRELRRTAYSGVPMT
ILSSRDHTCVHPEVVGNFNRNEKCMELLDGKNGKSCYFYHGVHKISDQHTLQTFQGMCKAWDIEELVSLGKKLKACPYYTARELIQDADI
IFCPYNYLLDAQIRESMDLNLKEQVVILDEAHNIEDCARESASYSVTEVQLRFARDELDSMVNNNIRKKDHEPLRAVCCSLINWLEANAE
YLVERDYESACKIWSGNEMLLTLHKMGITTATFPILQGHFSAVLQKEEKISPIYGKEEAREVPVISASTQIMLKGLFMVLDYLFRQNSRF
ADDYKIAIQQTYSWTNQIDISDKNGLLVLPKNKKRSRQKTAVHVLNFWCLNPAVAFSDINGKVQTIVLTSGTLSPMKSFSSELGVTFTIQ
LEANHIIKNSQVWVGTIGSGPKGRNLCATFQNTETFEFQDEVGALLLSVCQTVSQGILCFLPSYKLLEKLKERWLSTGLWHNLELVKTVI
VEPQGGEKTNFDELLQVYYDAIKYKGEKDGALLVAVCRGKVSEGLDFSDDNARAVITIGIPFPNVKDLQVELKRQYNDHHSKLRGLLPGR
QWYEIQAYRALNQALGRCIRHRNDWGALILVDDRFRNNPSRYISGLSKWVRQQIQHHSTFESALESLAEFSKKHQKVLNVSIKDRTNIQD
NESTLEVTSLKYSTSPYLLEAASHLSPENFVEDEAKICVQELQCPKIITKNSPLPSSIISRKEKNDPVFLEEAGKAEKIVISRSTSPTFN
KQTKRVSWSSFNSLGQYFTGKIPKATPELGSSENSASSPPRFKTEKMESKTVLPFTDKCESSNLTVNTSFGSCPQSETIISSLKIDATLT
RKNHSEHPLCSEEALDPDIELSLVSEEDKQSTSNRDFETEAEDESIYFTPELYDPEDTDEEKNDLAETDRGNRLANNSDCILAKDLFEIR

--------------------------------------------------------------
>85454_85454_10_SPAG9-BRIP1_SPAG9_chr17_49133773_ENST00000357122_BRIP1_chr17_59924581_ENST00000577598_length(transcript)=4166nt_BP=704nt
AGTTGGTGCAGCGGCGGTTGGGGTGAGAGCGCCTACGCCACCCCTCCCCTCCTCCGGCCCCGGCCCCCACCCCGCCGGGCCCAGCCCCAG
CCCCGGCCCGGGCTCCAGCCCTAGTACCCGTCCCAGCCCGAGTCGGGTCCGTCCCGTGCGGGCAGGTGCCGCCCCTCTGCCGGCGACGCC
CCGGGCCGCCCGCCCGTCCGCTTGCCACCATGGAGCTGGAGGACGGTGTGGTGTATCAGGAGGAGCCCGGCGGCTCCGGGGCCGTGATGT
CGGAGCGGGTGTCCGGCCTGGCCGGCTCCATCTACCGCGAGTTCGAGCGGCTTATCGGGCGCTATGACGAGGAGGTGGTCAAAGAGCTGA
TGCCGCTGGTGGTGGCTGTGCTGGAGAACCTGGACTCGGTGTTCGCGCAGGACCAGGAGCACCAGGTGGAGCTGGAGCTGCTGCGGGACG
ACAACGAGCAGCTCATCACCCAGTACGAGCGGGAGAAGGCGCTGCGCAAGCACGCTGAGGAGAAATTCATTGAATTTGAAGACTCTCAAG
AACAGGAAAAAAAGGACTTACAGACCCGAGTGGAATCTTTAGAATCTCAAACAAGACAACTTGAGCTGAAAGCGAAAAACTATGCTGACC
AGATTAGCAGACTTGAAGAAAGAGAAGCAGAACTGAAGAAGGAATATAATGCATTACATCAAAGACACACTGAGATTAGAAAACGTCATT
GCTTTGGAACAGAAGTACACAATTTGGATGCAAAAGTTGATTCAGGAAAGACTGTAAAACTCAACTCTCCACTGGAAAAGATAAACTCCT
TTTCGCCACAGAAACCCCCTGGCCACTGTTCTAGGTGCTGTTGTTCTACTAAACAAGGAAACAGTCAAGAGTCATCGAATACCATTAAGA
AGGATCATACAGGGAAATCCAAGATACCCAAAATATATTTTGGGACACGCACACACAAGCAGATTGCTCAGATTACTAGAGAGCTCCGGA
GGACGGCATATTCAGGGGTTCCAATGACTATTCTTTCCAGCAGGGATCATACTTGTGTCCATCCTGAGGTAGTCGGTAACTTCAACAGAA
ATGAGAAGTGCATGGAATTGCTAGATGGGAAAAACGGAAAATCCTGCTATTTTTATCATGGAGTTCATAAAATTAGTGATCAGCACACAT
TACAGACTTTCCAAGGGATGTGCAAAGCCTGGGATATAGAAGAACTTGTCAGCCTGGGGAAGAAACTAAAGGCCTGTCCATATTACACAG
CCCGAGAACTAATACAAGATGCTGACATCATATTTTGTCCCTACAACTATCTTCTAGATGCACAAATAAGGGAAAGTATGGATTTAAATC
TGAAAGAACAGGTTGTCATTTTAGATGAAGCTCATAACATCGAGGACTGTGCTCGGGAATCAGCAAGTTACAGTGTAACAGAAGTTCAGC
TTCGGTTTGCTCGGGATGAACTAGATAGTATGGTCAACAATAATATAAGGAAGAAAGATCATGAACCCCTACGAGCTGTGTGCTGTAGCC
TCATTAATTGGTTAGAAGCAAACGCTGAATATCTTGTAGAAAGAGATTATGAATCAGCTTGTAAAATATGGAGTGGAAATGAAATGCTCT
TAACTTTACACAAAATGGGTATCACCACTGCTACTTTTCCCATTTTGCAGGGACATTTTTCTGCTGTTCTTCAAAAAGAGGAAAAAATCT
CACCAATTTATGGTAAAGAGGAGGCAAGAGAAGTACCTGTTATTAGTGCATCAACTCAAATAATGCTTAAAGGACTTTTTATGGTACTTG
ACTATCTTTTTAGGCAAAATAGCAGATTTGCAGATGATTATAAAATTGCGATTCAACAGACTTACTCCTGGACAAATCAGATTGATATTT
CAGACAAAAATGGGTTGTTGGTTCTACCAAAAAATAAGAAACGTTCACGACAGAAAACTGCAGTTCATGTGCTAAACTTTTGGTGCTTAA
ATCCAGCTGTGGCCTTTTCAGATATTAATGGCAAAGTTCAGACCATTGTTTTGACATCTGGTACATTATCACCAATGAAATCCTTTTCGT
CAGAACTTGGTGTTACATTTACTATCCAGCTGGAGGCTAATCATATCATTAAAAATTCACAGGTTTGGGTTGGTACCATTGGGTCAGGCC
CCAAGGGTCGGAATCTCTGTGCTACCTTCCAGAATACTGAAACATTTGAGTTCCAAGATGAAGTGGGAGCACTTTTGTTATCTGTGTGCC
AGACTGTGAGCCAAGGAATTTTGTGTTTCTTGCCATCTTACAAGTTATTAGAAAAATTAAAAGAACGTTGGCTCTCTACTGGTTTATGGC
ATAATCTGGAGTTGGTGAAGACAGTCATTGTAGAACCACAGGGAGGAGAAAAAACAAATTTTGATGAATTACTGCAGGTGTACTATGACG
CAATCAAATACAAAGGAGAGAAAGATGGAGCTCTCCTGGTAGCAGTTTGTCGTGGTAAAGTGAGTGAGGGTCTGGATTTCTCAGATGACA
ATGCCCGTGCTGTCATAACAATAGGAATTCCTTTTCCAAATGTGAAAGATCTACAGGTTGAACTAAAACGACAATACAATGACCACCATT
CAAAATTGAGAGGTCTTCTACCTGGCCGTCAGTGGTATGAAATTCAAGCATACAGGGCCTTAAACCAGGCCCTTGGTAGATGTATTAGAC
ACAGAAATGATTGGGGAGCTCTTATTCTAGTGGATGATCGCTTTAGGAATAACCCAAGTCGCTATATATCTGGACTTTCTAAATGGGTAC
GGCAGCAGATTCAGCACCATTCAACCTTTGAAAGTGCACTGGAATCCTTGGCTGAATTTTCCAAAAAGCATCAAAAAGTTCTTAATGTAT
CCATAAAGGACAGAACCAATATACAGGACAATGAGTCTACACTTGAAGTGACCTCTTTAAAGTACAGTACCTCACCTTATTTACTGGAAG
CAGCAAGTCATCTATCACCAGAAAATTTTGTGGAAGATGAAGCAAAGATATGTGTCCAGGAACTACAGTGTCCTAAAATTATTACCAAAA
ATTCACCTCTACCAAGTAGCATTATCTCCAGAAAGGAGAAAAGTATGAAAAGTTCTTCCCATTTACCTTTGATAGAGAAGTCTTTCATTA
TATTTAGTGAAATGATATTTATTTGGGTATAGATTAATTCCTTAAATATGGTGGTTTGTAATATAAGGTGTTATCATAAAATAGTGAAAC
AGTATGGTGTACTGTAATGGGAACAAACTTTTGTCAGGAGACCAGAGCATATTTTCTGGTTTTCCACTAACTGGCTTTGCCACTTACTAG
CTTTGTGATCATGAGCAAGTCATTTGTCCTTTTTGAGTCGTAATAGGAAAAAAAAAATGCCTGCCTAGCTATCCCTTCAGGTTGGGTTGT
AAAGGTCAAAATTATAAATATCACAGCATTGTAAAGTACCATGTAAGTGGTAGATGTTATTCTAAAGGCTATATAAAAATTTGGCCTAAT
TTTTATGTAGATACTTCTATATGAACTACTTTTCCTATATAGATAGTTCTTATGAACTTATTTTTAGGAGGTGAGAGACATTTATTTTAA
GTGATGAAAAATAATATTTTAAAATATTTTGAAATAATCATCTGTATCAGATTGGCAAACTGTGGCCCATGGGCCAAATTTGGCCTGCTG
CCTGTTTTTGTAAATAAAGTTTAATGAAATGTAGTCATGCCCATTTATTTACATTTTAGAAACAACAGCAGAGTTGAGTATTTGTGTGTA
TTGCACTAGAACAGCATAATTGAGTAGTCGCAACAGATACATTATGCTCCACAAAGCCTAAATATTACTATCTGGCCTATGACAGAAAAG
GTTTGCCAAACTCTGGTCTATTCCATTGGATATAATTTCAGTTGTTTTAATTCATATATCCAAGGCGGGTGGATCATCCGAGGTCAGGAG
TCCGAGACCAGCCTGACCAGTGTGGTGAAACACCGTCTCTACTAAAAAAATACAAAAATTAGCTGGGTGTGGAGGCAGCTGTCTGTAATC
CCAGCTACTCAGGAGGCTGAGGCAGGAGAATTGCTTGAACTGGGAGGTGGAGGTTGCAGTGAGCCAGGATTGCGCCATTGCACTCCAGCC

>85454_85454_10_SPAG9-BRIP1_SPAG9_chr17_49133773_ENST00000357122_BRIP1_chr17_59924581_ENST00000577598_length(amino acids)=990AA_BP=165
MELEDGVVYQEEPGGSGAVMSERVSGLAGSIYREFERLIGRYDEEVVKELMPLVVAVLENLDSVFAQDQEHQVELELLRDDNEQLITQYE
REKALRKHAEEKFIEFEDSQEQEKKDLQTRVESLESQTRQLELKAKNYADQISRLEEREAELKKEYNALHQRHTEIRKRHCFGTEVHNLD
AKVDSGKTVKLNSPLEKINSFSPQKPPGHCSRCCCSTKQGNSQESSNTIKKDHTGKSKIPKIYFGTRTHKQIAQITRELRRTAYSGVPMT
ILSSRDHTCVHPEVVGNFNRNEKCMELLDGKNGKSCYFYHGVHKISDQHTLQTFQGMCKAWDIEELVSLGKKLKACPYYTARELIQDADI
IFCPYNYLLDAQIRESMDLNLKEQVVILDEAHNIEDCARESASYSVTEVQLRFARDELDSMVNNNIRKKDHEPLRAVCCSLINWLEANAE
YLVERDYESACKIWSGNEMLLTLHKMGITTATFPILQGHFSAVLQKEEKISPIYGKEEAREVPVISASTQIMLKGLFMVLDYLFRQNSRF
ADDYKIAIQQTYSWTNQIDISDKNGLLVLPKNKKRSRQKTAVHVLNFWCLNPAVAFSDINGKVQTIVLTSGTLSPMKSFSSELGVTFTIQ
LEANHIIKNSQVWVGTIGSGPKGRNLCATFQNTETFEFQDEVGALLLSVCQTVSQGILCFLPSYKLLEKLKERWLSTGLWHNLELVKTVI
VEPQGGEKTNFDELLQVYYDAIKYKGEKDGALLVAVCRGKVSEGLDFSDDNARAVITIGIPFPNVKDLQVELKRQYNDHHSKLRGLLPGR
QWYEIQAYRALNQALGRCIRHRNDWGALILVDDRFRNNPSRYISGLSKWVRQQIQHHSTFESALESLAEFSKKHQKVLNVSIKDRTNIQD
NESTLEVTSLKYSTSPYLLEAASHLSPENFVEDEAKICVQELQCPKIITKNSPLPSSIISRKEKSMKSSSHLPLIEKSFIIFSEMIFIWV

--------------------------------------------------------------
>85454_85454_11_SPAG9-BRIP1_SPAG9_chr17_49133773_ENST00000505279_BRIP1_chr17_59924581_ENST00000259008_length(transcript)=5846nt_BP=573nt
GTCGGGTCCGTCCCGTGCGGGCAGGTGCCGCCCCTCTGCCGGCGACGCCCCGGGCCGCCCGCCCGTCCGCTTGCCACCATGGAGCTGGAG
GACGGTGTGGTGTATCAGGAGGAGCCCGGCGGCTCCGGGGCCGTGATGTCGGAGCGGGTGTCCGGCCTGGCCGGCTCCATCTACCGCGAG
TTCGAGCGGCTTATCGGGCGCTATGACGAGGAGGTGGTCAAAGAGCTGATGCCGCTGGTGGTGGCTGTGCTGGAGAACCTGGACTCGGTG
TTCGCGCAGGACCAGGAGCACCAGGTGGAGCTGGAGCTGCTGCGGGACGACAACGAGCAGCTCATCACCCAGTACGAGCGGGAGAAGGCG
CTGCGCAAGCACGCTGAGGAGAAATTCATTGAATTTGAAGACTCTCAAGAACAGGAAAAAAAGGACTTACAGACCCGAGTGGAATCTTTA
GAATCTCAAACAAGACAACTTGAGCTGAAAGCGAAAAACTATGCTGACCAGATTAGCAGACTTGAAGAAAGAGAAGCAGAACTGAAGAAG
GAATATAATGCATTACATCAAAGACACACTGAGATTAGAAAACGTCATTGCTTTGGAACAGAAGTACACAATTTGGATGCAAAAGTTGAT
TCAGGAAAGACTGTAAAACTCAACTCTCCACTGGAAAAGATAAACTCCTTTTCGCCACAGAAACCCCCTGGCCACTGTTCTAGGTGCTGT
TGTTCTACTAAACAAGGAAACAGTCAAGAGTCATCGAATACCATTAAGAAGGATCATACAGGGAAATCCAAGATACCCAAAATATATTTT
GGGACACGCACACACAAGCAGATTGCTCAGATTACTAGAGAGCTCCGGAGGACGGCATATTCAGGGGTTCCAATGACTATTCTTTCCAGC
AGGGATCATACTTGTGTCCATCCTGAGGTAGTCGGTAACTTCAACAGAAATGAGAAGTGCATGGAATTGCTAGATGGGAAAAACGGAAAA
TCCTGCTATTTTTATCATGGAGTTCATAAAATTAGTGATCAGCACACATTACAGACTTTCCAAGGGATGTGCAAAGCCTGGGATATAGAA
GAACTTGTCAGCCTGGGGAAGAAACTAAAGGCCTGTCCATATTACACAGCCCGAGAACTAATACAAGATGCTGACATCATATTTTGTCCC
TACAACTATCTTCTAGATGCACAAATAAGGGAAAGTATGGATTTAAATCTGAAAGAACAGGTTGTCATTTTAGATGAAGCTCATAACATC
GAGGACTGTGCTCGGGAATCAGCAAGTTACAGTGTAACAGAAGTTCAGCTTCGGTTTGCTCGGGATGAACTAGATAGTATGGTCAACAAT
AATATAAGGAAGAAAGATCATGAACCCCTACGAGCTGTGTGCTGTAGCCTCATTAATTGGTTAGAAGCAAACGCTGAATATCTTGTAGAA
AGAGATTATGAATCAGCTTGTAAAATATGGAGTGGAAATGAAATGCTCTTAACTTTACACAAAATGGGTATCACCACTGCTACTTTTCCC
ATTTTGCAGGGACATTTTTCTGCTGTTCTTCAAAAAGAGGAAAAAATCTCACCAATTTATGGTAAAGAGGAGGCAAGAGAAGTACCTGTT
ATTAGTGCATCAACTCAAATAATGCTTAAAGGACTTTTTATGGTACTTGACTATCTTTTTAGGCAAAATAGCAGATTTGCAGATGATTAT
AAAATTGCGATTCAACAGACTTACTCCTGGACAAATCAGATTGATATTTCAGACAAAAATGGGTTGTTGGTTCTACCAAAAAATAAGAAA
CGTTCACGACAGAAAACTGCAGTTCATGTGCTAAACTTTTGGTGCTTAAATCCAGCTGTGGCCTTTTCAGATATTAATGGCAAAGTTCAG
ACCATTGTTTTGACATCTGGTACATTATCACCAATGAAATCCTTTTCGTCAGAACTTGGTGTTACATTTACTATCCAGCTGGAGGCTAAT
CATATCATTAAAAATTCACAGGTTTGGGTTGGTACCATTGGGTCAGGCCCCAAGGGTCGGAATCTCTGTGCTACCTTCCAGAATACTGAA
ACATTTGAGTTCCAAGATGAAGTGGGAGCACTTTTGTTATCTGTGTGCCAGACTGTGAGCCAAGGAATTTTGTGTTTCTTGCCATCTTAC
AAGTTATTAGAAAAATTAAAAGAACGTTGGCTCTCTACTGGTTTATGGCATAATCTGGAGTTGGTGAAGACAGTCATTGTAGAACCACAG
GGAGGAGAAAAAACAAATTTTGATGAATTACTGCAGGTGTACTATGACGCAATCAAATACAAAGGAGAGAAAGATGGAGCTCTCCTGGTA
GCAGTTTGTCGTGGTAAAGTGAGTGAGGGTCTGGATTTCTCAGATGACAATGCCCGTGCTGTCATAACAATAGGAATTCCTTTTCCAAAT
GTGAAAGATCTACAGGTTGAACTAAAACGACAATACAATGACCACCATTCAAAATTGAGAGGTCTTCTACCTGGCCGTCAGTGGTATGAA
ATTCAAGCATACAGGGCCTTAAACCAGGCCCTTGGTAGATGTATTAGACACAGAAATGATTGGGGAGCTCTTATTCTAGTGGATGATCGC
TTTAGGAATAACCCAAGTCGCTATATATCTGGACTTTCTAAATGGGTACGGCAGCAGATTCAGCACCATTCAACCTTTGAAAGTGCACTG
GAATCCTTGGCTGAATTTTCCAAAAAGCATCAAAAAGTTCTTAATGTATCCATAAAGGACAGAACCAATATACAGGACAATGAGTCTACA
CTTGAAGTGACCTCTTTAAAGTACAGTACCTCACCTTATTTACTGGAAGCAGCAAGTCATCTATCACCAGAAAATTTTGTGGAAGATGAA
GCAAAGATATGTGTCCAGGAACTACAGTGTCCTAAAATTATTACCAAAAATTCACCTCTACCAAGTAGCATTATCTCCAGAAAGGAGAAA
AATGATCCAGTATTCCTGGAAGAAGCAGGGAAAGCAGAAAAAATTGTGATTTCCAGATCCACAAGCCCAACTTTCAACAAACAAACAAAG
AGAGTTAGCTGGTCAAGCTTTAATTCTTTGGGACAGTATTTTACTGGTAAAATACCGAAGGCAACACCTGAGCTCGGGTCATCAGAGAAT
AGTGCCTCTAGTCCTCCCCGTTTCAAAACAGAGAAGATGGAAAGTAAAACTGTTTTGCCCTTCACTGATAAATGTGAATCCTCAAATCTG
ACAGTAAACACATCGTTTGGATCATGCCCTCAATCAGAAACCATTATTTCATCATTAAAGATTGATGCCACCCTTACTAGAAAAAATCAT
TCTGAACATCCGCTCTGTTCTGAAGAAGCCCTGGATCCAGACATTGAATTGTCTCTAGTAAGTGAAGAAGATAAACAGTCCACTTCAAAT
AGAGATTTTGAAACAGAAGCAGAAGATGAATCTATCTATTTTACACCTGAACTTTATGATCCTGAAGATACAGATGAAGAAAAAAATGAC
CTAGCTGAAACTGATAGAGGAAATAGATTGGCTAACAATTCAGATTGCATTTTAGCTAAAGACCTTTTTGAAATTAGAACTATAAAAGAA
GTAGATTCAGCCAGAGAAGTGAAAGCTGAGGATTGCATAGATACAAAGTTGAATGGAATTCTGCATATTGAAGAAAGTAAAATTGATGAC
ATTGATGGTAATGTAAAAACAACTTGGATAAATGAACTGGAACTGGGAAAAACTCATGAAATAGAAATAAAGAACTTTAAACCATCTCCT
TCCAAAAATAAAGGCATGTTTCCTGGTTTTAAGTAATAATACTTAACTCTCAAGCTAAGTAAAAATATGTCATCATGCTTATGTTAAACT
CTGTTGTAAGTAATAATTTGTAAATTGAATAAGTGGCATACTTTTTAAAAAACTATTTTATGTTCAGAAATGTAAATGTTATTATTCTTG
AGTTTTTGGGTTTTTTTTTTTGAGACAGAGTCTTGGTCTGTTGCCCAGGCTGGAATGCAGTGGTGTGCTCTGGGCTCACTGCAACCTTCA
CCTCCAGGTTCAAGTGATTCTCCTGCCTCAGCCTTCTGAGTAGCTGGGACTACAGGTGTGCACCACCATGCCCAGCTAGTTTTTGTATTT
TTAGTAGAGATGGGGTTTCACCATGTTGGCCAGGCTGGTCTCGAACTCCTGGCCTCGTGATCTGCCCTTCTCTGCCTCCCTAAGTTGCTG
GGATTACAGGTGTGAGCCACAGTGCCTGGCCCATTCTTGAGTTTTGATAAAGTAATTCATACAAAGTACTGTCCTCAAATAAGTCTTCCT
TAGCTAAATGCAATTTAAAATTATTCAAAGATCCTAGGGCACTTCTAGTTTCACGTAAATATTCATATTAGGTGGTTCTCTTCATCCATT
TGTTTTCACACTGATACATAAAAATTAACAGCAGTCTAATCTAGTGACACCTCAGTCATATTTCGCTATAGATTTTACCTCAAATCAGTC
CAAGACTTTTTCAGAGATCACCATTTGTCTTGAAAGGTTTATTTCGTTATTAAACTGCCTACTTATAAGTAATTAAGAGAAATTAAGAAA
GTAGTATGCATTTTTAATTGAAATTGTTTTACATTCTTTGTATAATAAACCTAAAACCAAACATGTCATAAACAAATTGACGTAAAGATA
TAAAATGCCAAATGAAGTATTCCAAATTTTCTATTCTAATTATTTAGCTTCACCATCATTGTGGAAAAAAATACTAGATCCTGCTTAGTA
TTATATATTTTTCCTAGTGGATCAGTGAGTAATAAGTACCAAACACTAGACTAGAAGGTAATTTCTACATTGTTTAGAAAGGGTGAAACA
ATTTATCCCCTCTGGTATTGTTCTAGCATAAGCTTTAGTTATACAATGATTAAGATAGAAAACTTCATATATAAATTTGATAAGCAAACC
CACATTTATAGCTGCAGCTAAAATATGTTTCCTTAGGGCACAGTAATCCTTTCTGTGAATTTTGACCTTGTTTGTGTTTTTGTGAATGAA
GCTATATGTCTAATCAAAAATGATTATAAAAGAGGCTCATCTCTGACATCATTCCAAAAATACATTCATTGATCTCTTTTTAAGAAACAT
CTGTTATTCACTGGGCATTGGGACTTTTTGTGAGTAATTTGAATTGAAATTTTATGAGCTATCCAAGAATTCTGTATGGTCTATTATTTT
CAAGTCAAAATTTCCAGTAAGGATTTACTTTACATTTCATTTGGATAAATGAATCATTATATAGGTATGTCTTTGCTTCCATTTTGAGAC
ATTTAGATTTTTACAGCCTGTTTCTATAGCATTTGATGTTACAACTCTAAGCGTAGTTCAAAGACATTTAAATTGACAAGTTACCAGTTA
AAGAATTTAGAATATATTAGATCCCATCTAGTATTATATATTTTTTCTAGTTGATCATTGAGCAGTAAATACCAAATACTCGATTAGAAG
GTAATTTTTACATTGTTTTGAAAGGGTGAAACAATTTATCTCCTCTGGTATTATTCTTAAACCACAGATAGGGATAGTAGGGTAGTGAAA
CGAATAAATACCTGGTAGAAGACAAGAGACTTGGGCTCTACACCTGGCTCTGCCACTGATTTGCTAAGTCATATTGGCAATCACCACACC
CTTCAGGGAATTAGTTTCATCTGTAAAATGCAGCGGTTAGTACTATAAAATCATACAAATTTCTTTGTGCTTTGAGAATCTATAAAGGAA

>85454_85454_11_SPAG9-BRIP1_SPAG9_chr17_49133773_ENST00000505279_BRIP1_chr17_59924581_ENST00000259008_length(amino acids)=1245AA_BP=165
MELEDGVVYQEEPGGSGAVMSERVSGLAGSIYREFERLIGRYDEEVVKELMPLVVAVLENLDSVFAQDQEHQVELELLRDDNEQLITQYE
REKALRKHAEEKFIEFEDSQEQEKKDLQTRVESLESQTRQLELKAKNYADQISRLEEREAELKKEYNALHQRHTEIRKRHCFGTEVHNLD
AKVDSGKTVKLNSPLEKINSFSPQKPPGHCSRCCCSTKQGNSQESSNTIKKDHTGKSKIPKIYFGTRTHKQIAQITRELRRTAYSGVPMT
ILSSRDHTCVHPEVVGNFNRNEKCMELLDGKNGKSCYFYHGVHKISDQHTLQTFQGMCKAWDIEELVSLGKKLKACPYYTARELIQDADI
IFCPYNYLLDAQIRESMDLNLKEQVVILDEAHNIEDCARESASYSVTEVQLRFARDELDSMVNNNIRKKDHEPLRAVCCSLINWLEANAE
YLVERDYESACKIWSGNEMLLTLHKMGITTATFPILQGHFSAVLQKEEKISPIYGKEEAREVPVISASTQIMLKGLFMVLDYLFRQNSRF
ADDYKIAIQQTYSWTNQIDISDKNGLLVLPKNKKRSRQKTAVHVLNFWCLNPAVAFSDINGKVQTIVLTSGTLSPMKSFSSELGVTFTIQ
LEANHIIKNSQVWVGTIGSGPKGRNLCATFQNTETFEFQDEVGALLLSVCQTVSQGILCFLPSYKLLEKLKERWLSTGLWHNLELVKTVI
VEPQGGEKTNFDELLQVYYDAIKYKGEKDGALLVAVCRGKVSEGLDFSDDNARAVITIGIPFPNVKDLQVELKRQYNDHHSKLRGLLPGR
QWYEIQAYRALNQALGRCIRHRNDWGALILVDDRFRNNPSRYISGLSKWVRQQIQHHSTFESALESLAEFSKKHQKVLNVSIKDRTNIQD
NESTLEVTSLKYSTSPYLLEAASHLSPENFVEDEAKICVQELQCPKIITKNSPLPSSIISRKEKNDPVFLEEAGKAEKIVISRSTSPTFN
KQTKRVSWSSFNSLGQYFTGKIPKATPELGSSENSASSPPRFKTEKMESKTVLPFTDKCESSNLTVNTSFGSCPQSETIISSLKIDATLT
RKNHSEHPLCSEEALDPDIELSLVSEEDKQSTSNRDFETEAEDESIYFTPELYDPEDTDEEKNDLAETDRGNRLANNSDCILAKDLFEIR

--------------------------------------------------------------
>85454_85454_12_SPAG9-BRIP1_SPAG9_chr17_49133773_ENST00000505279_BRIP1_chr17_59924581_ENST00000577598_length(transcript)=4035nt_BP=573nt
GTCGGGTCCGTCCCGTGCGGGCAGGTGCCGCCCCTCTGCCGGCGACGCCCCGGGCCGCCCGCCCGTCCGCTTGCCACCATGGAGCTGGAG
GACGGTGTGGTGTATCAGGAGGAGCCCGGCGGCTCCGGGGCCGTGATGTCGGAGCGGGTGTCCGGCCTGGCCGGCTCCATCTACCGCGAG
TTCGAGCGGCTTATCGGGCGCTATGACGAGGAGGTGGTCAAAGAGCTGATGCCGCTGGTGGTGGCTGTGCTGGAGAACCTGGACTCGGTG
TTCGCGCAGGACCAGGAGCACCAGGTGGAGCTGGAGCTGCTGCGGGACGACAACGAGCAGCTCATCACCCAGTACGAGCGGGAGAAGGCG
CTGCGCAAGCACGCTGAGGAGAAATTCATTGAATTTGAAGACTCTCAAGAACAGGAAAAAAAGGACTTACAGACCCGAGTGGAATCTTTA
GAATCTCAAACAAGACAACTTGAGCTGAAAGCGAAAAACTATGCTGACCAGATTAGCAGACTTGAAGAAAGAGAAGCAGAACTGAAGAAG
GAATATAATGCATTACATCAAAGACACACTGAGATTAGAAAACGTCATTGCTTTGGAACAGAAGTACACAATTTGGATGCAAAAGTTGAT
TCAGGAAAGACTGTAAAACTCAACTCTCCACTGGAAAAGATAAACTCCTTTTCGCCACAGAAACCCCCTGGCCACTGTTCTAGGTGCTGT
TGTTCTACTAAACAAGGAAACAGTCAAGAGTCATCGAATACCATTAAGAAGGATCATACAGGGAAATCCAAGATACCCAAAATATATTTT
GGGACACGCACACACAAGCAGATTGCTCAGATTACTAGAGAGCTCCGGAGGACGGCATATTCAGGGGTTCCAATGACTATTCTTTCCAGC
AGGGATCATACTTGTGTCCATCCTGAGGTAGTCGGTAACTTCAACAGAAATGAGAAGTGCATGGAATTGCTAGATGGGAAAAACGGAAAA
TCCTGCTATTTTTATCATGGAGTTCATAAAATTAGTGATCAGCACACATTACAGACTTTCCAAGGGATGTGCAAAGCCTGGGATATAGAA
GAACTTGTCAGCCTGGGGAAGAAACTAAAGGCCTGTCCATATTACACAGCCCGAGAACTAATACAAGATGCTGACATCATATTTTGTCCC
TACAACTATCTTCTAGATGCACAAATAAGGGAAAGTATGGATTTAAATCTGAAAGAACAGGTTGTCATTTTAGATGAAGCTCATAACATC
GAGGACTGTGCTCGGGAATCAGCAAGTTACAGTGTAACAGAAGTTCAGCTTCGGTTTGCTCGGGATGAACTAGATAGTATGGTCAACAAT
AATATAAGGAAGAAAGATCATGAACCCCTACGAGCTGTGTGCTGTAGCCTCATTAATTGGTTAGAAGCAAACGCTGAATATCTTGTAGAA
AGAGATTATGAATCAGCTTGTAAAATATGGAGTGGAAATGAAATGCTCTTAACTTTACACAAAATGGGTATCACCACTGCTACTTTTCCC
ATTTTGCAGGGACATTTTTCTGCTGTTCTTCAAAAAGAGGAAAAAATCTCACCAATTTATGGTAAAGAGGAGGCAAGAGAAGTACCTGTT
ATTAGTGCATCAACTCAAATAATGCTTAAAGGACTTTTTATGGTACTTGACTATCTTTTTAGGCAAAATAGCAGATTTGCAGATGATTAT
AAAATTGCGATTCAACAGACTTACTCCTGGACAAATCAGATTGATATTTCAGACAAAAATGGGTTGTTGGTTCTACCAAAAAATAAGAAA
CGTTCACGACAGAAAACTGCAGTTCATGTGCTAAACTTTTGGTGCTTAAATCCAGCTGTGGCCTTTTCAGATATTAATGGCAAAGTTCAG
ACCATTGTTTTGACATCTGGTACATTATCACCAATGAAATCCTTTTCGTCAGAACTTGGTGTTACATTTACTATCCAGCTGGAGGCTAAT
CATATCATTAAAAATTCACAGGTTTGGGTTGGTACCATTGGGTCAGGCCCCAAGGGTCGGAATCTCTGTGCTACCTTCCAGAATACTGAA
ACATTTGAGTTCCAAGATGAAGTGGGAGCACTTTTGTTATCTGTGTGCCAGACTGTGAGCCAAGGAATTTTGTGTTTCTTGCCATCTTAC
AAGTTATTAGAAAAATTAAAAGAACGTTGGCTCTCTACTGGTTTATGGCATAATCTGGAGTTGGTGAAGACAGTCATTGTAGAACCACAG
GGAGGAGAAAAAACAAATTTTGATGAATTACTGCAGGTGTACTATGACGCAATCAAATACAAAGGAGAGAAAGATGGAGCTCTCCTGGTA
GCAGTTTGTCGTGGTAAAGTGAGTGAGGGTCTGGATTTCTCAGATGACAATGCCCGTGCTGTCATAACAATAGGAATTCCTTTTCCAAAT
GTGAAAGATCTACAGGTTGAACTAAAACGACAATACAATGACCACCATTCAAAATTGAGAGGTCTTCTACCTGGCCGTCAGTGGTATGAA
ATTCAAGCATACAGGGCCTTAAACCAGGCCCTTGGTAGATGTATTAGACACAGAAATGATTGGGGAGCTCTTATTCTAGTGGATGATCGC
TTTAGGAATAACCCAAGTCGCTATATATCTGGACTTTCTAAATGGGTACGGCAGCAGATTCAGCACCATTCAACCTTTGAAAGTGCACTG
GAATCCTTGGCTGAATTTTCCAAAAAGCATCAAAAAGTTCTTAATGTATCCATAAAGGACAGAACCAATATACAGGACAATGAGTCTACA
CTTGAAGTGACCTCTTTAAAGTACAGTACCTCACCTTATTTACTGGAAGCAGCAAGTCATCTATCACCAGAAAATTTTGTGGAAGATGAA
GCAAAGATATGTGTCCAGGAACTACAGTGTCCTAAAATTATTACCAAAAATTCACCTCTACCAAGTAGCATTATCTCCAGAAAGGAGAAA
AGTATGAAAAGTTCTTCCCATTTACCTTTGATAGAGAAGTCTTTCATTATATTTAGTGAAATGATATTTATTTGGGTATAGATTAATTCC
TTAAATATGGTGGTTTGTAATATAAGGTGTTATCATAAAATAGTGAAACAGTATGGTGTACTGTAATGGGAACAAACTTTTGTCAGGAGA
CCAGAGCATATTTTCTGGTTTTCCACTAACTGGCTTTGCCACTTACTAGCTTTGTGATCATGAGCAAGTCATTTGTCCTTTTTGAGTCGT
AATAGGAAAAAAAAAATGCCTGCCTAGCTATCCCTTCAGGTTGGGTTGTAAAGGTCAAAATTATAAATATCACAGCATTGTAAAGTACCA
TGTAAGTGGTAGATGTTATTCTAAAGGCTATATAAAAATTTGGCCTAATTTTTATGTAGATACTTCTATATGAACTACTTTTCCTATATA
GATAGTTCTTATGAACTTATTTTTAGGAGGTGAGAGACATTTATTTTAAGTGATGAAAAATAATATTTTAAAATATTTTGAAATAATCAT
CTGTATCAGATTGGCAAACTGTGGCCCATGGGCCAAATTTGGCCTGCTGCCTGTTTTTGTAAATAAAGTTTAATGAAATGTAGTCATGCC
CATTTATTTACATTTTAGAAACAACAGCAGAGTTGAGTATTTGTGTGTATTGCACTAGAACAGCATAATTGAGTAGTCGCAACAGATACA
TTATGCTCCACAAAGCCTAAATATTACTATCTGGCCTATGACAGAAAAGGTTTGCCAAACTCTGGTCTATTCCATTGGATATAATTTCAG
TTGTTTTAATTCATATATCCAAGGCGGGTGGATCATCCGAGGTCAGGAGTCCGAGACCAGCCTGACCAGTGTGGTGAAACACCGTCTCTA
CTAAAAAAATACAAAAATTAGCTGGGTGTGGAGGCAGCTGTCTGTAATCCCAGCTACTCAGGAGGCTGAGGCAGGAGAATTGCTTGAACT

>85454_85454_12_SPAG9-BRIP1_SPAG9_chr17_49133773_ENST00000505279_BRIP1_chr17_59924581_ENST00000577598_length(amino acids)=990AA_BP=165
MELEDGVVYQEEPGGSGAVMSERVSGLAGSIYREFERLIGRYDEEVVKELMPLVVAVLENLDSVFAQDQEHQVELELLRDDNEQLITQYE
REKALRKHAEEKFIEFEDSQEQEKKDLQTRVESLESQTRQLELKAKNYADQISRLEEREAELKKEYNALHQRHTEIRKRHCFGTEVHNLD
AKVDSGKTVKLNSPLEKINSFSPQKPPGHCSRCCCSTKQGNSQESSNTIKKDHTGKSKIPKIYFGTRTHKQIAQITRELRRTAYSGVPMT
ILSSRDHTCVHPEVVGNFNRNEKCMELLDGKNGKSCYFYHGVHKISDQHTLQTFQGMCKAWDIEELVSLGKKLKACPYYTARELIQDADI
IFCPYNYLLDAQIRESMDLNLKEQVVILDEAHNIEDCARESASYSVTEVQLRFARDELDSMVNNNIRKKDHEPLRAVCCSLINWLEANAE
YLVERDYESACKIWSGNEMLLTLHKMGITTATFPILQGHFSAVLQKEEKISPIYGKEEAREVPVISASTQIMLKGLFMVLDYLFRQNSRF
ADDYKIAIQQTYSWTNQIDISDKNGLLVLPKNKKRSRQKTAVHVLNFWCLNPAVAFSDINGKVQTIVLTSGTLSPMKSFSSELGVTFTIQ
LEANHIIKNSQVWVGTIGSGPKGRNLCATFQNTETFEFQDEVGALLLSVCQTVSQGILCFLPSYKLLEKLKERWLSTGLWHNLELVKTVI
VEPQGGEKTNFDELLQVYYDAIKYKGEKDGALLVAVCRGKVSEGLDFSDDNARAVITIGIPFPNVKDLQVELKRQYNDHHSKLRGLLPGR
QWYEIQAYRALNQALGRCIRHRNDWGALILVDDRFRNNPSRYISGLSKWVRQQIQHHSTFESALESLAEFSKKHQKVLNVSIKDRTNIQD
NESTLEVTSLKYSTSPYLLEAASHLSPENFVEDEAKICVQELQCPKIITKNSPLPSSIISRKEKSMKSSSHLPLIEKSFIIFSEMIFIWV

--------------------------------------------------------------

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Fusion Gene PPI Analysis for SPAG9-BRIP1


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with
TgeneBRIP1chr17:49133772chr17:59924581ENST00000259008420888_1063169.01250.0BRCA1
TgeneBRIP1chr17:49133773chr17:59924581ENST00000259008420888_1063169.01250.0BRCA1


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for SPAG9-BRIP1


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for SPAG9-BRIP1


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource