Home

Download

Statistics

Examples

Help

Contact

	Fusion Gene Summary
	Fusion Gene ORF analysis
	Fusion Genomic Features
	Fusion Protein Features
	Fusion Gene Sequence
	Fusion Gene PPI analysis
	Related Drugs
	Related Diseases

Fusion gene:SPAG9-KPNA3 (FusionGDB2 ID:85458)

Fusion Gene Summary for SPAG9-KPNA3

Fusion gene summary

Fusion gene information	Fusion gene name: SPAG9-KPNA3
	Fusion gene ID: 85458
		Hgene	Tgene
	Gene symbol	SPAG9	KPNA3
	Gene ID	9043	3839
	Gene name	sperm associated antigen 9	karyopherin subunit alpha 3
	Synonyms	CT89\|HLC-6\|HLC4\|HLC6\|JIP-4\|JIP4\|JLP\|PHET\|PIG6	IPOA4\|SRP1\|SRP1gamma\|SRP4\|hSRP1
	Cytomap	17q21.33	13q14.2
	Type of gene	protein-coding	protein-coding
	Description	C-Jun-amino-terminal kinase-interacting protein 4JNK interacting proteinJNK/SAPK-associated proteinMax-binding proteinc-Jun NH2-terminal kinase-associated leucine zipper proteincancer/testis antigen 89human lung cancer oncogene 6 proteinlung cancer	importin subunit alpha-4SRP1-gammaimportin alpha 4importin alpha Q2importin alpha-3importin subunit alpha-3karyopherin alpha 3 (importin alpha 4)qip2
	Modification date	20200315	20200313
	UniProtAcc	.	O00505
	Ensembl transtripts involved in fusion gene	ENST00000262013, ENST00000357122, ENST00000505279, ENST00000509724, ENST00000510283,	ENST00000261667,
Fusion gene scores	* DoF score	20 X 21 X 10=4200	11 X 9 X 5=495
	# samples	25	11
	** MAII score	log2(25/4200*10)=-4.0703893278914 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0	log2(11/495*10)=-2.16992500144231 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0
Context	PubMed: SPAG9 [Title/Abstract] AND KPNA3 [Title/Abstract] AND fusion [Title/Abstract]
Most frequent breakpoint	SPAG9(49197715)-KPNA3(50321129), # samples:1
Anticipated loss of major functional domain due to fusion event.

* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Partner	Gene	GO ID	GO term	PubMed ID
Hgene	SPAG9	GO:0042147	retrograde transport, endosome to Golgi	19056739

Fusion gene breakpoints across SPAG9 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion gene breakpoints across KPNA3 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

Source	Disease	Sample	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
ChimerDB4	STAD	TCGA-BR-A4PE-01A	SPAG9	chr17	49197715	-	KPNA3	chr13	50321129	-

Top

Fusion Gene ORF analysis for SPAG9-KPNA3

Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

ORF	Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
In-frame	ENST00000262013	ENST00000261667	SPAG9	chr17	49197715	-	KPNA3	chr13	50321129	-
In-frame	ENST00000357122	ENST00000261667	SPAG9	chr17	49197715	-	KPNA3	chr13	50321129	-
In-frame	ENST00000505279	ENST00000261667	SPAG9	chr17	49197715	-	KPNA3	chr13	50321129	-
intron-3CDS	ENST00000509724	ENST00000261667	SPAG9	chr17	49197715	-	KPNA3	chr13	50321129	-
intron-3CDS	ENST00000510283	ENST00000261667	SPAG9	chr17	49197715	-	KPNA3	chr13	50321129	-

ORFfinder result based on the fusion transcript sequence of in-frame fusion genes.

Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	Seq length (transcript)	BP loci (transcript)	Predicted start (transcript)	Predicted stop (transcript)	Seq length (amino acids)
ENST00000262013	SPAG9	chr17	49197715	-	ENST00000261667	KPNA3	chr13	50321129	-	4498	512	209	2008	599
ENST00000505279	SPAG9	chr17	49197715	-	ENST00000261667	KPNA3	chr13	50321129	-	4367	381	78	1877	599
ENST00000357122	SPAG9	chr17	49197715	-	ENST00000261667	KPNA3	chr13	50321129	-	4498	512	209	2008	599

DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.

Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	No-coding score	Coding score
ENST00000262013	ENST00000261667	SPAG9	chr17	49197715	-	KPNA3	chr13	50321129	-	0.000335959	0.99966407
ENST00000505279	ENST00000261667	SPAG9	chr17	49197715	-	KPNA3	chr13	50321129	-	0.000324383	0.99967563
ENST00000357122	ENST00000261667	SPAG9	chr17	49197715	-	KPNA3	chr13	50321129	-	0.000335959	0.99966407

Top

Fusion Genomic Features for SPAG9-KPNA3

FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.

Hgene

Hchr

Hbp

Hstrand

Tgene

Tchr

Tbp

Tstrand

1-p

p (fusion gene breakpoint)

Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.

Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

Top

Fusion Protein Features for SPAG9-KPNA3

Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr17:49197715/chr13:50321129)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.

Main function of each fusion partner protein. (from UniProt)

Hgene	Tgene
.	KPNA3 O00505
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.	FUNCTION: Functions in nuclear protein import as an adapter protein for nuclear receptor KPNB1. Binds specifically and directly to substrates containing either a simple or bipartite NLS motif. Docking of the importin/substrate complex to the nuclear pore complex (NPC) is mediated by KPNB1 through binding to nucleoporin FxFG repeats and the complex is subsequently translocated through the pore by an energy requiring, Ran-dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to importin-beta and the three components separate and importin-alpha and -beta are re-exported from the nucleus to the cytoplasm where GTP hydrolysis releases Ran from importin. The directionality of nuclear import is thought to be conferred by an asymmetric distribution of the GTP- and GDP-bound forms of Ran between the cytoplasm and nucleus. In vitro, mediates the nuclear import of human cytomegalovirus UL84 by recognizing a non-classical NLS. Recognizes NLSs of influenza A virus nucleoprotein probably through ARM repeats 7-9.

Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at
download page

* Minus value of BPloci means that the break pointn is located before the CDS.

- In-frame and retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

Hgene

SPAG9

chr17:49197715

chr13:50321129

ENST00000262013

7_95

101

1322.0

Domain

RH1

Hgene

SPAG9

chr17:49197715

chr13:50321129

ENST00000357122

7_95

101

1308.0

Domain

RH1

Hgene

SPAG9

chr17:49197715

chr13:50321129

ENST00000505279

7_95

101

1312.0

Domain

RH1

Tgene

KPNA3

chr17:49197715

chr13:50321129

ENST00000261667

43_52

522.0

Motif

Nuclear localization signal

Tgene

KPNA3

chr17:49197715

chr13:50321129

ENST00000261667

137_229

522.0

Region

NLS binding site (major)

Tgene

KPNA3

chr17:49197715

chr13:50321129

ENST00000261667

306_394

522.0

Region

NLS binding site (minor)

Tgene

KPNA3

chr17:49197715

chr13:50321129

ENST00000261667

107_149

522.0

Repeat

Note=ARM 2

Tgene

KPNA3

chr17:49197715

chr13:50321129

ENST00000261667

150_194

522.0

Repeat

Note=ARM 3

Tgene

KPNA3

chr17:49197715

chr13:50321129

ENST00000261667

195_233

522.0

Repeat

Note=ARM 4

Tgene

KPNA3

chr17:49197715

chr13:50321129

ENST00000261667

234_278

522.0

Repeat

Note=ARM 5

Tgene

KPNA3

chr17:49197715

chr13:50321129

ENST00000261667

279_318

522.0

Repeat

Note=ARM 6

Tgene

KPNA3

chr17:49197715

chr13:50321129

ENST00000261667

319_360

522.0

Repeat

Note=ARM 7

Tgene

KPNA3

chr17:49197715

chr13:50321129

ENST00000261667

361_400

522.0

Repeat

Note=ARM 8

Tgene

KPNA3

chr17:49197715

chr13:50321129

ENST00000261667

401_443

522.0

Repeat

Note=ARM 9

Tgene

KPNA3

chr17:49197715

chr13:50321129

ENST00000261667

447_485

522.0

Repeat

Note=ARM 10%3B atypical

Tgene

KPNA3

chr17:49197715

chr13:50321129

ENST00000261667

66_106

522.0

Repeat

Note=ARM 1%3B truncated

- In-frame and not-retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

Hgene

SPAG9

chr17:49197715

chr13:50321129

ENST00000262013

408_534

101

1322.0

Coiled coil

Ontology_term=ECO:0000269

Hgene

SPAG9

chr17:49197715

chr13:50321129

ENST00000262013

66_166

101

1322.0

Coiled coil

Ontology_term=ECO:0000255

Hgene

SPAG9

chr17:49197715

chr13:50321129

ENST00000262013

724_758

101

1322.0

Coiled coil

Ontology_term=ECO:0000255

Hgene

SPAG9

chr17:49197715

chr13:50321129

ENST00000357122

408_534

101

1308.0

Coiled coil

Ontology_term=ECO:0000269

Hgene

SPAG9

chr17:49197715

chr13:50321129

ENST00000357122

66_166

101

1308.0

Coiled coil

Ontology_term=ECO:0000255

Hgene

SPAG9

chr17:49197715

chr13:50321129

ENST00000357122

724_758

101

1308.0

Coiled coil

Ontology_term=ECO:0000255

Hgene

SPAG9

chr17:49197715

chr13:50321129

ENST00000505279

408_534

101

1312.0

Coiled coil

Ontology_term=ECO:0000269

Hgene

SPAG9

chr17:49197715

chr13:50321129

ENST00000505279

66_166

101

1312.0

Coiled coil

Ontology_term=ECO:0000255

Hgene

SPAG9

chr17:49197715

chr13:50321129

ENST00000505279

724_758

101

1312.0

Coiled coil

Ontology_term=ECO:0000255

Hgene

SPAG9

chr17:49197715

chr13:50321129

ENST00000510283

408_534

1178.0

Coiled coil

Ontology_term=ECO:0000269

Hgene

SPAG9

chr17:49197715

chr13:50321129

ENST00000510283

66_166

1178.0

Coiled coil

Ontology_term=ECO:0000255

Hgene

SPAG9

chr17:49197715

chr13:50321129

ENST00000510283

724_758

1178.0

Coiled coil

Ontology_term=ECO:0000255

Hgene

SPAG9

chr17:49197715

chr13:50321129

ENST00000262013

500_571

101

1322.0

Domain

RH2

Hgene

SPAG9

chr17:49197715

chr13:50321129

ENST00000357122

500_571

101

1308.0

Domain

RH2

Hgene

SPAG9

chr17:49197715

chr13:50321129

ENST00000505279

500_571

101

1312.0

Domain

RH2

Hgene

SPAG9

chr17:49197715

chr13:50321129

ENST00000510283

500_571

1178.0

Domain

RH2

Hgene

SPAG9

chr17:49197715

chr13:50321129

ENST00000510283

7_95

1178.0

Domain

RH1

Tgene

KPNA3

chr17:49197715

chr13:50321129

ENST00000261667

2_58

522.0

Domain

IBB

Top

Fusion Gene Sequence for SPAG9-KPNA3

For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.

>85458_85458_1_SPAG9-KPNA3_SPAG9_chr17_49197715_ENST00000262013_KPNA3_chr13_50321129_ENST00000261667_length(transcript)=4498nt_BP=512nt
AGTTGGTGCAGCGGCGGTTGGGGTGAGAGCGCCTACGCCACCCCTCCCCTCCTCCGGCCCCGGCCCCCACCCCGCCGGGCCCAGCCCCAG
CCCCGGCCCGGGCTCCAGCCCTAGTACCCGTCCCAGCCCGAGTCGGGTCCGTCCCGTGCGGGCAGGTGCCGCCCCTCTGCCGGCGACGCC
CCGGGCCGCCCGCCCGTCCGCTTGCCACCATGGAGCTGGAGGACGGTGTGGTGTATCAGGAGGAGCCCGGCGGCTCCGGGGCCGTGATGT
CGGAGCGGGTGTCCGGCCTGGCCGGCTCCATCTACCGCGAGTTCGAGCGGCTTATCGGGCGCTATGACGAGGAGGTGGTCAAAGAGCTGA
TGCCGCTGGTGGTGGCTGTGCTGGAGAACCTGGACTCGGTGTTCGCGCAGGACCAGGAGCACCAGGTGGAGCTGGAGCTGCTGCGGGACG
ACAACGAGCAGCTCATCACCCAGTACGAGCGGGAGAAGGCGCTGCGCAAGCACGCTGAGGAGACAATGCGAAGACATAGAAATGAAGTGA
CAGTGGAACTGCGGAAGAACAAAAGAGATGAACACTTATTGAAAAAGAGAAATGTTCCCCAAGAAGAAAGTCTAGAAGATTCAGATGTTG
ATGCTGATTTTAAAGCACAAAATGTAACCCTAGAAGCTATATTGCAGAATGCCACAAGTGATAACCCAGTGGTCCAATTGAGTGCTGTCC
AGGCAGCAAGAAAACTGTTATCCAGTGACAGAAATCCACCGATTGATGACTTAATAAAATCTGGGATTTTACCAATTCTAGTCAAATGTC
TAGAAAGGGATGATAATCCTTCATTACAGTTTGAAGCTGCTTGGGCATTAACTAACATAGCATCAGGAACTTCTGCACAGACTCAAGCTG
TTGTGCAGTCTAATGCAGTACCTCTTTTTCTGAGACTTCTTCGTTCACCACATCAGAATGTTTGTGAACAAGCAGTATGGGCTTTGGGAA
ACATTATAGGTGATGGTCCTCAATGTAGAGATTATGTCATATCACTGGGAGTTGTCAAACCTCTTCTGTCCTTCATCAGTCCCTCCATCC
CCATCACCTTCCTTCGGAACGTCACATGGGTCATTGTCAATCTCTGCAGGAATAAGGATCCCCCGCCGCCTATGGAGACAGTTCAGGAGA
TTTTGCCAGCTTTATGTGTCCTCATATACCATACAGATATAAACATTCTTGTAGACACTGTTTGGGCTCTGTCATACTTGACAGATGGAG
GTAATGAACAGATACAGATGGTTATTGATTCAGGAGTTGTGCCCTTTCTTGTGCCCCTTCTGAGCCATCAGGAAGTCAAAGTTCAAACAG
CAGCCCTCAGAGCAGTTGGCAACATAGTGACTGGCACCGACGAGCAGACCCAGGTTGTTCTCAATTGTGATGTCCTGTCACACTTCCCAA
ATCTCTTATCACACCCAAAAGAGAAGATAAATAAGGAAGCAGTGTGGTTCCTTTCCAACATAACAGCAGGCAACCAGCAACAAGTTCAAG
CTGTAATAGATGCTGGATTAATTCCTATGATAATTCATCAGCTTGCTAAGGGGGACTTTGGAACACAAAAAGAAGCTGCTTGGGCAATCA
GCAACTTAACAATAAGTGGCAGAAAAGATCAGGTTGAGTACCTTGTACAGCAGAATGTAATACCACCGTTCTGTAATTTACTGTCAGTGA
AAGATTCTCAAGTGGTTCAGGTGGTTCTAGATGGTCTAAAAAACATTCTGATAATGGCCGGTGATGAAGCAAGCACAATAGCTGAAATAA
TAGAGGAATGTGGAGGTTTGGAGAAAATTGAAGTTTTACAGCAACATGAAAATGAAGACATATATAAATTAGCATTTGAAATCATAGATC
AGTATTTCTCTGGTGATGATATTGATGAAGATCCCTGCCTCATTCCTGAAGCAACACAAGGAGGTACCTACAATTTTGATCCAACAGCCA
ACCTTCAAACAAAAGAATTTAATTTTTAAATTCAGTTGAGTGCAGCATCTTTCCCACATTCAATATGAAGCACCACCAGATGGCTACCAA
ATGATAAGAACAACAGCAACAAAAGGCTCCAAAACACACATGCCTCTTTGTTTTGATGCTTCTAAAGCAAGCCATGTCTCAGTCACTTTG
CAGTTGCCAAAAGTCACTATCACATGGACTGTAAATGCATATGCATGATTTCCTAAACTGTTTTAGAACTCTCCTTAACAATCTCAACTA
CCCTATTTTTCCCTGTTCCCTGGTGCCACAGGCTGACAACTGCAGTCTCCAGTTTAGAATAAATATTCCATAGTGGTGACATGTCAGCTG
CCCACTGATACTCCTTTGGAAAATGGTGCGCTGTGGATCAAGACACTTTGGTATGATGCATATACAAGTTGGAAGACTAAAGAGGTGCAG
TGTGATCTGAGCCTCCATCATTGTCCTCCACAAACATATTTTCATATTCTTTATGTGGAAGAATAGATTTTAAAGTACAAGCCAAATGAT
TTTCATTGGTGGAACTGACACAAAAAAAGTAACTTAAAAACAAGAAACTTGGTTATTGAATAAACAGATAAGTTTAAAAAAAAAAAAAAA
CTACTTCATCTACCAGTAATTGATGTGTTTATTATCTGCCTCAGAAGCCAGGGTTGGAGGAAGAACTTTAGATATGGATATTAATGCTTT
TGCCATTATACCTAATTTTTGAGAACAGCAAGCCCTATTTGACCACTCTCTTCAGCCTGTGTGTTCCTGCTGTTTTGAAGTAATCAAATG
CTGTGCATGGTATTTTACCTGAGCTGCAACCTGTTATGGACTTGAACTTCTGTTTAAGTTGAAAGCAAGAGTCCCTGAGTATAAAGGAAA
AACAGCAAAACAAAAAGCAAACAAAAAAAAACTGCAAAAGTCTAAAATACCCATTGGTGATGTTTTTTAAAAAAATCTTGCTTTCAGCTT
TCAGGAGTTAATATTCTTTGTTTTAATTTGATAATTGGATATGGTTGATTTATATTGGGTTTAAACTGTGGAGCTTTCATGTTTACTGTA
ATTTAGTCTTAAAATATTTTTTACTTAGTAACCAGTGCTTTTGATAATGTGGTTGGCAACAAACCAGCAACTATTTAGAAGTGTCATAAG
AGTTCATTCTTTGAGTATTGGGAAAGTTAATTCAGATCCTACTCAAAAAGCATCTTCACATATTAAAAGATTCAGACAGGGATCTGTGTA
GAGGAGTAATTTGCAGTTATTTAACATAAACCTGATTTGCAGTGATCTCTAAGTAATTCTGCAAAATCCGGTATTACTATGTCAAGTTAT
TGCTTTTGGTAAATTGTCTGACCCAGTTATTAATGAAAGAATATGGATTTAAAAATTTTTAAACTAAATAATTTGTGCTGTCACAGAAAT
GGTATTGTTGCTCTTGTTTACTGGGTATAATTTCCCAATGCATTGATGTGAAGGGATAGAAAATCTAAACTAATTTAGTTATCCATTGGG
GGGTGTATTTACTGTGATGAAGATGAGACAGATGCCATCAGAGCTTTGTGAATCAGCTGGGGTGTTTTCACTGATAAACAACACATAGCA
GGTGTGCATTCATTACAAATATATGTATCTGCCAAGGTGGAGCCACTTTAAAGAGTGAGTTTTGTCTTGTATCTAAAGTGGATACAAGCG
TATGTTTAAACTGCAAGATTTTTACTTGCTAGAGAATCTGTTTTAATATAGTGGTTTGGCCTCTGATTATTTATAGGTTTTATAAATTTT
AGAATCAATTTCTCTTTAAGGTGGCTCAGATTTTTCAACTCTTGTGCACATAAAATTGAGTTGAAGTTCATTGTGCCTTTTTTTCTTTAT
CCAAATTTTGAGTTAAAGCTTCATATGGTAACTGCATCCTGTTCGGACACTATAGTCTAAATTTTTGAAACTGTGTGGTGTTCGCTAAAA
GTAGGAATAACAACGTAAAAGCTAATTAAGGTCACAAACTTCGGTGAAACCCTTAAAAGTCCAAATCTTCTTGATATTGTGAACCGTACC
CCTTCCAGTTTAGTTTCTTCTGGACTTTCCTTACTTAACTGACAGTTACCTTTTAAAATTTGCACACATTATGATTAAAATTGGGCCTCT
ACTGTGATGATTCCTATTTCCTCTCATGTTTTAAAGTGCAAACTAACATTTAAGTGAACATTAGCATCAAGTAGTGCAGACACTTGTATG
CATTTCCTTGATTCAATTTGTGACCTTACCAGTTTTGAATTGGAATTGCACCATTTCGTAGATAAAGGAAACTAAGTATATTGCTGCACT
TTTAAGTTTTCAAAACAGTGTTTAAAAATTGCATTGTTATTTTTTTTTAAACTCAGTTTAAAAAGACTAAAACGTTCTTTCAAAAGAGGC

>85458_85458_1_SPAG9-KPNA3_SPAG9_chr17_49197715_ENST00000262013_KPNA3_chr13_50321129_ENST00000261667_length(amino acids)=599AA_BP=101
MELEDGVVYQEEPGGSGAVMSERVSGLAGSIYREFERLIGRYDEEVVKELMPLVVAVLENLDSVFAQDQEHQVELELLRDDNEQLITQYE
REKALRKHAEETMRRHRNEVTVELRKNKRDEHLLKKRNVPQEESLEDSDVDADFKAQNVTLEAILQNATSDNPVVQLSAVQAARKLLSSD
RNPPIDDLIKSGILPILVKCLERDDNPSLQFEAAWALTNIASGTSAQTQAVVQSNAVPLFLRLLRSPHQNVCEQAVWALGNIIGDGPQCR
DYVISLGVVKPLLSFISPSIPITFLRNVTWVIVNLCRNKDPPPPMETVQEILPALCVLIYHTDINILVDTVWALSYLTDGGNEQIQMVID
SGVVPFLVPLLSHQEVKVQTAALRAVGNIVTGTDEQTQVVLNCDVLSHFPNLLSHPKEKINKEAVWFLSNITAGNQQQVQAVIDAGLIPM
IIHQLAKGDFGTQKEAAWAISNLTISGRKDQVEYLVQQNVIPPFCNLLSVKDSQVVQVVLDGLKNILIMAGDEASTIAEIIEECGGLEKI

--------------------------------------------------------------
>85458_85458_2_SPAG9-KPNA3_SPAG9_chr17_49197715_ENST00000357122_KPNA3_chr13_50321129_ENST00000261667_length(transcript)=4498nt_BP=512nt
AGTTGGTGCAGCGGCGGTTGGGGTGAGAGCGCCTACGCCACCCCTCCCCTCCTCCGGCCCCGGCCCCCACCCCGCCGGGCCCAGCCCCAG
CCCCGGCCCGGGCTCCAGCCCTAGTACCCGTCCCAGCCCGAGTCGGGTCCGTCCCGTGCGGGCAGGTGCCGCCCCTCTGCCGGCGACGCC
CCGGGCCGCCCGCCCGTCCGCTTGCCACCATGGAGCTGGAGGACGGTGTGGTGTATCAGGAGGAGCCCGGCGGCTCCGGGGCCGTGATGT
CGGAGCGGGTGTCCGGCCTGGCCGGCTCCATCTACCGCGAGTTCGAGCGGCTTATCGGGCGCTATGACGAGGAGGTGGTCAAAGAGCTGA
TGCCGCTGGTGGTGGCTGTGCTGGAGAACCTGGACTCGGTGTTCGCGCAGGACCAGGAGCACCAGGTGGAGCTGGAGCTGCTGCGGGACG
ACAACGAGCAGCTCATCACCCAGTACGAGCGGGAGAAGGCGCTGCGCAAGCACGCTGAGGAGACAATGCGAAGACATAGAAATGAAGTGA
CAGTGGAACTGCGGAAGAACAAAAGAGATGAACACTTATTGAAAAAGAGAAATGTTCCCCAAGAAGAAAGTCTAGAAGATTCAGATGTTG
ATGCTGATTTTAAAGCACAAAATGTAACCCTAGAAGCTATATTGCAGAATGCCACAAGTGATAACCCAGTGGTCCAATTGAGTGCTGTCC
AGGCAGCAAGAAAACTGTTATCCAGTGACAGAAATCCACCGATTGATGACTTAATAAAATCTGGGATTTTACCAATTCTAGTCAAATGTC
TAGAAAGGGATGATAATCCTTCATTACAGTTTGAAGCTGCTTGGGCATTAACTAACATAGCATCAGGAACTTCTGCACAGACTCAAGCTG
TTGTGCAGTCTAATGCAGTACCTCTTTTTCTGAGACTTCTTCGTTCACCACATCAGAATGTTTGTGAACAAGCAGTATGGGCTTTGGGAA
ACATTATAGGTGATGGTCCTCAATGTAGAGATTATGTCATATCACTGGGAGTTGTCAAACCTCTTCTGTCCTTCATCAGTCCCTCCATCC
CCATCACCTTCCTTCGGAACGTCACATGGGTCATTGTCAATCTCTGCAGGAATAAGGATCCCCCGCCGCCTATGGAGACAGTTCAGGAGA
TTTTGCCAGCTTTATGTGTCCTCATATACCATACAGATATAAACATTCTTGTAGACACTGTTTGGGCTCTGTCATACTTGACAGATGGAG
GTAATGAACAGATACAGATGGTTATTGATTCAGGAGTTGTGCCCTTTCTTGTGCCCCTTCTGAGCCATCAGGAAGTCAAAGTTCAAACAG
CAGCCCTCAGAGCAGTTGGCAACATAGTGACTGGCACCGACGAGCAGACCCAGGTTGTTCTCAATTGTGATGTCCTGTCACACTTCCCAA
ATCTCTTATCACACCCAAAAGAGAAGATAAATAAGGAAGCAGTGTGGTTCCTTTCCAACATAACAGCAGGCAACCAGCAACAAGTTCAAG
CTGTAATAGATGCTGGATTAATTCCTATGATAATTCATCAGCTTGCTAAGGGGGACTTTGGAACACAAAAAGAAGCTGCTTGGGCAATCA
GCAACTTAACAATAAGTGGCAGAAAAGATCAGGTTGAGTACCTTGTACAGCAGAATGTAATACCACCGTTCTGTAATTTACTGTCAGTGA
AAGATTCTCAAGTGGTTCAGGTGGTTCTAGATGGTCTAAAAAACATTCTGATAATGGCCGGTGATGAAGCAAGCACAATAGCTGAAATAA
TAGAGGAATGTGGAGGTTTGGAGAAAATTGAAGTTTTACAGCAACATGAAAATGAAGACATATATAAATTAGCATTTGAAATCATAGATC
AGTATTTCTCTGGTGATGATATTGATGAAGATCCCTGCCTCATTCCTGAAGCAACACAAGGAGGTACCTACAATTTTGATCCAACAGCCA
ACCTTCAAACAAAAGAATTTAATTTTTAAATTCAGTTGAGTGCAGCATCTTTCCCACATTCAATATGAAGCACCACCAGATGGCTACCAA
ATGATAAGAACAACAGCAACAAAAGGCTCCAAAACACACATGCCTCTTTGTTTTGATGCTTCTAAAGCAAGCCATGTCTCAGTCACTTTG
CAGTTGCCAAAAGTCACTATCACATGGACTGTAAATGCATATGCATGATTTCCTAAACTGTTTTAGAACTCTCCTTAACAATCTCAACTA
CCCTATTTTTCCCTGTTCCCTGGTGCCACAGGCTGACAACTGCAGTCTCCAGTTTAGAATAAATATTCCATAGTGGTGACATGTCAGCTG
CCCACTGATACTCCTTTGGAAAATGGTGCGCTGTGGATCAAGACACTTTGGTATGATGCATATACAAGTTGGAAGACTAAAGAGGTGCAG
TGTGATCTGAGCCTCCATCATTGTCCTCCACAAACATATTTTCATATTCTTTATGTGGAAGAATAGATTTTAAAGTACAAGCCAAATGAT
TTTCATTGGTGGAACTGACACAAAAAAAGTAACTTAAAAACAAGAAACTTGGTTATTGAATAAACAGATAAGTTTAAAAAAAAAAAAAAA
CTACTTCATCTACCAGTAATTGATGTGTTTATTATCTGCCTCAGAAGCCAGGGTTGGAGGAAGAACTTTAGATATGGATATTAATGCTTT
TGCCATTATACCTAATTTTTGAGAACAGCAAGCCCTATTTGACCACTCTCTTCAGCCTGTGTGTTCCTGCTGTTTTGAAGTAATCAAATG
CTGTGCATGGTATTTTACCTGAGCTGCAACCTGTTATGGACTTGAACTTCTGTTTAAGTTGAAAGCAAGAGTCCCTGAGTATAAAGGAAA
AACAGCAAAACAAAAAGCAAACAAAAAAAAACTGCAAAAGTCTAAAATACCCATTGGTGATGTTTTTTAAAAAAATCTTGCTTTCAGCTT
TCAGGAGTTAATATTCTTTGTTTTAATTTGATAATTGGATATGGTTGATTTATATTGGGTTTAAACTGTGGAGCTTTCATGTTTACTGTA
ATTTAGTCTTAAAATATTTTTTACTTAGTAACCAGTGCTTTTGATAATGTGGTTGGCAACAAACCAGCAACTATTTAGAAGTGTCATAAG
AGTTCATTCTTTGAGTATTGGGAAAGTTAATTCAGATCCTACTCAAAAAGCATCTTCACATATTAAAAGATTCAGACAGGGATCTGTGTA
GAGGAGTAATTTGCAGTTATTTAACATAAACCTGATTTGCAGTGATCTCTAAGTAATTCTGCAAAATCCGGTATTACTATGTCAAGTTAT
TGCTTTTGGTAAATTGTCTGACCCAGTTATTAATGAAAGAATATGGATTTAAAAATTTTTAAACTAAATAATTTGTGCTGTCACAGAAAT
GGTATTGTTGCTCTTGTTTACTGGGTATAATTTCCCAATGCATTGATGTGAAGGGATAGAAAATCTAAACTAATTTAGTTATCCATTGGG
GGGTGTATTTACTGTGATGAAGATGAGACAGATGCCATCAGAGCTTTGTGAATCAGCTGGGGTGTTTTCACTGATAAACAACACATAGCA
GGTGTGCATTCATTACAAATATATGTATCTGCCAAGGTGGAGCCACTTTAAAGAGTGAGTTTTGTCTTGTATCTAAAGTGGATACAAGCG
TATGTTTAAACTGCAAGATTTTTACTTGCTAGAGAATCTGTTTTAATATAGTGGTTTGGCCTCTGATTATTTATAGGTTTTATAAATTTT
AGAATCAATTTCTCTTTAAGGTGGCTCAGATTTTTCAACTCTTGTGCACATAAAATTGAGTTGAAGTTCATTGTGCCTTTTTTTCTTTAT
CCAAATTTTGAGTTAAAGCTTCATATGGTAACTGCATCCTGTTCGGACACTATAGTCTAAATTTTTGAAACTGTGTGGTGTTCGCTAAAA
GTAGGAATAACAACGTAAAAGCTAATTAAGGTCACAAACTTCGGTGAAACCCTTAAAAGTCCAAATCTTCTTGATATTGTGAACCGTACC
CCTTCCAGTTTAGTTTCTTCTGGACTTTCCTTACTTAACTGACAGTTACCTTTTAAAATTTGCACACATTATGATTAAAATTGGGCCTCT
ACTGTGATGATTCCTATTTCCTCTCATGTTTTAAAGTGCAAACTAACATTTAAGTGAACATTAGCATCAAGTAGTGCAGACACTTGTATG
CATTTCCTTGATTCAATTTGTGACCTTACCAGTTTTGAATTGGAATTGCACCATTTCGTAGATAAAGGAAACTAAGTATATTGCTGCACT
TTTAAGTTTTCAAAACAGTGTTTAAAAATTGCATTGTTATTTTTTTTTAAACTCAGTTTAAAAAGACTAAAACGTTCTTTCAAAAGAGGC

>85458_85458_2_SPAG9-KPNA3_SPAG9_chr17_49197715_ENST00000357122_KPNA3_chr13_50321129_ENST00000261667_length(amino acids)=599AA_BP=101
MELEDGVVYQEEPGGSGAVMSERVSGLAGSIYREFERLIGRYDEEVVKELMPLVVAVLENLDSVFAQDQEHQVELELLRDDNEQLITQYE
REKALRKHAEETMRRHRNEVTVELRKNKRDEHLLKKRNVPQEESLEDSDVDADFKAQNVTLEAILQNATSDNPVVQLSAVQAARKLLSSD
RNPPIDDLIKSGILPILVKCLERDDNPSLQFEAAWALTNIASGTSAQTQAVVQSNAVPLFLRLLRSPHQNVCEQAVWALGNIIGDGPQCR
DYVISLGVVKPLLSFISPSIPITFLRNVTWVIVNLCRNKDPPPPMETVQEILPALCVLIYHTDINILVDTVWALSYLTDGGNEQIQMVID
SGVVPFLVPLLSHQEVKVQTAALRAVGNIVTGTDEQTQVVLNCDVLSHFPNLLSHPKEKINKEAVWFLSNITAGNQQQVQAVIDAGLIPM
IIHQLAKGDFGTQKEAAWAISNLTISGRKDQVEYLVQQNVIPPFCNLLSVKDSQVVQVVLDGLKNILIMAGDEASTIAEIIEECGGLEKI

--------------------------------------------------------------
>85458_85458_3_SPAG9-KPNA3_SPAG9_chr17_49197715_ENST00000505279_KPNA3_chr13_50321129_ENST00000261667_length(transcript)=4367nt_BP=381nt
GTCGGGTCCGTCCCGTGCGGGCAGGTGCCGCCCCTCTGCCGGCGACGCCCCGGGCCGCCCGCCCGTCCGCTTGCCACCATGGAGCTGGAG
GACGGTGTGGTGTATCAGGAGGAGCCCGGCGGCTCCGGGGCCGTGATGTCGGAGCGGGTGTCCGGCCTGGCCGGCTCCATCTACCGCGAG
TTCGAGCGGCTTATCGGGCGCTATGACGAGGAGGTGGTCAAAGAGCTGATGCCGCTGGTGGTGGCTGTGCTGGAGAACCTGGACTCGGTG
TTCGCGCAGGACCAGGAGCACCAGGTGGAGCTGGAGCTGCTGCGGGACGACAACGAGCAGCTCATCACCCAGTACGAGCGGGAGAAGGCG
CTGCGCAAGCACGCTGAGGAGACAATGCGAAGACATAGAAATGAAGTGACAGTGGAACTGCGGAAGAACAAAAGAGATGAACACTTATTG
AAAAAGAGAAATGTTCCCCAAGAAGAAAGTCTAGAAGATTCAGATGTTGATGCTGATTTTAAAGCACAAAATGTAACCCTAGAAGCTATA
TTGCAGAATGCCACAAGTGATAACCCAGTGGTCCAATTGAGTGCTGTCCAGGCAGCAAGAAAACTGTTATCCAGTGACAGAAATCCACCG
ATTGATGACTTAATAAAATCTGGGATTTTACCAATTCTAGTCAAATGTCTAGAAAGGGATGATAATCCTTCATTACAGTTTGAAGCTGCT
TGGGCATTAACTAACATAGCATCAGGAACTTCTGCACAGACTCAAGCTGTTGTGCAGTCTAATGCAGTACCTCTTTTTCTGAGACTTCTT
CGTTCACCACATCAGAATGTTTGTGAACAAGCAGTATGGGCTTTGGGAAACATTATAGGTGATGGTCCTCAATGTAGAGATTATGTCATA
TCACTGGGAGTTGTCAAACCTCTTCTGTCCTTCATCAGTCCCTCCATCCCCATCACCTTCCTTCGGAACGTCACATGGGTCATTGTCAAT
CTCTGCAGGAATAAGGATCCCCCGCCGCCTATGGAGACAGTTCAGGAGATTTTGCCAGCTTTATGTGTCCTCATATACCATACAGATATA
AACATTCTTGTAGACACTGTTTGGGCTCTGTCATACTTGACAGATGGAGGTAATGAACAGATACAGATGGTTATTGATTCAGGAGTTGTG
CCCTTTCTTGTGCCCCTTCTGAGCCATCAGGAAGTCAAAGTTCAAACAGCAGCCCTCAGAGCAGTTGGCAACATAGTGACTGGCACCGAC
GAGCAGACCCAGGTTGTTCTCAATTGTGATGTCCTGTCACACTTCCCAAATCTCTTATCACACCCAAAAGAGAAGATAAATAAGGAAGCA
GTGTGGTTCCTTTCCAACATAACAGCAGGCAACCAGCAACAAGTTCAAGCTGTAATAGATGCTGGATTAATTCCTATGATAATTCATCAG
CTTGCTAAGGGGGACTTTGGAACACAAAAAGAAGCTGCTTGGGCAATCAGCAACTTAACAATAAGTGGCAGAAAAGATCAGGTTGAGTAC
CTTGTACAGCAGAATGTAATACCACCGTTCTGTAATTTACTGTCAGTGAAAGATTCTCAAGTGGTTCAGGTGGTTCTAGATGGTCTAAAA
AACATTCTGATAATGGCCGGTGATGAAGCAAGCACAATAGCTGAAATAATAGAGGAATGTGGAGGTTTGGAGAAAATTGAAGTTTTACAG
CAACATGAAAATGAAGACATATATAAATTAGCATTTGAAATCATAGATCAGTATTTCTCTGGTGATGATATTGATGAAGATCCCTGCCTC
ATTCCTGAAGCAACACAAGGAGGTACCTACAATTTTGATCCAACAGCCAACCTTCAAACAAAAGAATTTAATTTTTAAATTCAGTTGAGT
GCAGCATCTTTCCCACATTCAATATGAAGCACCACCAGATGGCTACCAAATGATAAGAACAACAGCAACAAAAGGCTCCAAAACACACAT
GCCTCTTTGTTTTGATGCTTCTAAAGCAAGCCATGTCTCAGTCACTTTGCAGTTGCCAAAAGTCACTATCACATGGACTGTAAATGCATA
TGCATGATTTCCTAAACTGTTTTAGAACTCTCCTTAACAATCTCAACTACCCTATTTTTCCCTGTTCCCTGGTGCCACAGGCTGACAACT
GCAGTCTCCAGTTTAGAATAAATATTCCATAGTGGTGACATGTCAGCTGCCCACTGATACTCCTTTGGAAAATGGTGCGCTGTGGATCAA
GACACTTTGGTATGATGCATATACAAGTTGGAAGACTAAAGAGGTGCAGTGTGATCTGAGCCTCCATCATTGTCCTCCACAAACATATTT
TCATATTCTTTATGTGGAAGAATAGATTTTAAAGTACAAGCCAAATGATTTTCATTGGTGGAACTGACACAAAAAAAGTAACTTAAAAAC
AAGAAACTTGGTTATTGAATAAACAGATAAGTTTAAAAAAAAAAAAAAACTACTTCATCTACCAGTAATTGATGTGTTTATTATCTGCCT
CAGAAGCCAGGGTTGGAGGAAGAACTTTAGATATGGATATTAATGCTTTTGCCATTATACCTAATTTTTGAGAACAGCAAGCCCTATTTG
ACCACTCTCTTCAGCCTGTGTGTTCCTGCTGTTTTGAAGTAATCAAATGCTGTGCATGGTATTTTACCTGAGCTGCAACCTGTTATGGAC
TTGAACTTCTGTTTAAGTTGAAAGCAAGAGTCCCTGAGTATAAAGGAAAAACAGCAAAACAAAAAGCAAACAAAAAAAAACTGCAAAAGT
CTAAAATACCCATTGGTGATGTTTTTTAAAAAAATCTTGCTTTCAGCTTTCAGGAGTTAATATTCTTTGTTTTAATTTGATAATTGGATA
TGGTTGATTTATATTGGGTTTAAACTGTGGAGCTTTCATGTTTACTGTAATTTAGTCTTAAAATATTTTTTACTTAGTAACCAGTGCTTT
TGATAATGTGGTTGGCAACAAACCAGCAACTATTTAGAAGTGTCATAAGAGTTCATTCTTTGAGTATTGGGAAAGTTAATTCAGATCCTA
CTCAAAAAGCATCTTCACATATTAAAAGATTCAGACAGGGATCTGTGTAGAGGAGTAATTTGCAGTTATTTAACATAAACCTGATTTGCA
GTGATCTCTAAGTAATTCTGCAAAATCCGGTATTACTATGTCAAGTTATTGCTTTTGGTAAATTGTCTGACCCAGTTATTAATGAAAGAA
TATGGATTTAAAAATTTTTAAACTAAATAATTTGTGCTGTCACAGAAATGGTATTGTTGCTCTTGTTTACTGGGTATAATTTCCCAATGC
ATTGATGTGAAGGGATAGAAAATCTAAACTAATTTAGTTATCCATTGGGGGGTGTATTTACTGTGATGAAGATGAGACAGATGCCATCAG
AGCTTTGTGAATCAGCTGGGGTGTTTTCACTGATAAACAACACATAGCAGGTGTGCATTCATTACAAATATATGTATCTGCCAAGGTGGA
GCCACTTTAAAGAGTGAGTTTTGTCTTGTATCTAAAGTGGATACAAGCGTATGTTTAAACTGCAAGATTTTTACTTGCTAGAGAATCTGT
TTTAATATAGTGGTTTGGCCTCTGATTATTTATAGGTTTTATAAATTTTAGAATCAATTTCTCTTTAAGGTGGCTCAGATTTTTCAACTC
TTGTGCACATAAAATTGAGTTGAAGTTCATTGTGCCTTTTTTTCTTTATCCAAATTTTGAGTTAAAGCTTCATATGGTAACTGCATCCTG
TTCGGACACTATAGTCTAAATTTTTGAAACTGTGTGGTGTTCGCTAAAAGTAGGAATAACAACGTAAAAGCTAATTAAGGTCACAAACTT
CGGTGAAACCCTTAAAAGTCCAAATCTTCTTGATATTGTGAACCGTACCCCTTCCAGTTTAGTTTCTTCTGGACTTTCCTTACTTAACTG
ACAGTTACCTTTTAAAATTTGCACACATTATGATTAAAATTGGGCCTCTACTGTGATGATTCCTATTTCCTCTCATGTTTTAAAGTGCAA
ACTAACATTTAAGTGAACATTAGCATCAAGTAGTGCAGACACTTGTATGCATTTCCTTGATTCAATTTGTGACCTTACCAGTTTTGAATT
GGAATTGCACCATTTCGTAGATAAAGGAAACTAAGTATATTGCTGCACTTTTAAGTTTTCAAAACAGTGTTTAAAAATTGCATTGTTATT
TTTTTTTAAACTCAGTTTAAAAAGACTAAAACGTTCTTTCAAAAGAGGCATCTAAATGTGTTCCTAATTTTGTATATGGGCTTAGGTTTT

>85458_85458_3_SPAG9-KPNA3_SPAG9_chr17_49197715_ENST00000505279_KPNA3_chr13_50321129_ENST00000261667_length(amino acids)=599AA_BP=101
MELEDGVVYQEEPGGSGAVMSERVSGLAGSIYREFERLIGRYDEEVVKELMPLVVAVLENLDSVFAQDQEHQVELELLRDDNEQLITQYE
REKALRKHAEETMRRHRNEVTVELRKNKRDEHLLKKRNVPQEESLEDSDVDADFKAQNVTLEAILQNATSDNPVVQLSAVQAARKLLSSD
RNPPIDDLIKSGILPILVKCLERDDNPSLQFEAAWALTNIASGTSAQTQAVVQSNAVPLFLRLLRSPHQNVCEQAVWALGNIIGDGPQCR
DYVISLGVVKPLLSFISPSIPITFLRNVTWVIVNLCRNKDPPPPMETVQEILPALCVLIYHTDINILVDTVWALSYLTDGGNEQIQMVID
SGVVPFLVPLLSHQEVKVQTAALRAVGNIVTGTDEQTQVVLNCDVLSHFPNLLSHPKEKINKEAVWFLSNITAGNQQQVQAVIDAGLIPM
IIHQLAKGDFGTQKEAAWAISNLTISGRKDQVEYLVQQNVIPPFCNLLSVKDSQVVQVVLDGLKNILIMAGDEASTIAEIIEECGGLEKI

--------------------------------------------------------------

Top

Fusion Gene PPI Analysis for SPAG9-KPNA3

Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in
ChiPPI page.

Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)

Hgene

Hgene's interactors

Tgene

Tgene's interactors

- Retained PPIs in in-frame fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Still interaction with

- Lost PPIs in in-frame fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Interaction lost with

- Retained PPIs, but lost function due to frame-shift fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Interaction lost with

Top

Related Drugs for SPAG9-KPNA3

Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)

Partner

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

Top

Related Diseases for SPAG9-KPNA3

Diseases associated with fusion partners.
(DisGeNet 4.0)

Partner

Gene

Disease ID

Disease name

# pubmeds

Source