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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:SPAG9-SKAP1 (FusionGDB2 ID:85465)

Fusion Gene Summary for SPAG9-SKAP1

check button Fusion gene summary
Fusion gene informationFusion gene name: SPAG9-SKAP1
Fusion gene ID: 85465
HgeneTgene
Gene symbol

SPAG9

SKAP1

Gene ID

9043

8631

Gene namesperm associated antigen 9src kinase associated phosphoprotein 1
SynonymsCT89|HLC-6|HLC4|HLC6|JIP-4|JIP4|JLP|PHET|PIG6HEL-S-81p|SCAP1|SKAP55
Cytomap

17q21.33

17q21.32

Type of geneprotein-codingprotein-coding
DescriptionC-Jun-amino-terminal kinase-interacting protein 4JNK interacting proteinJNK/SAPK-associated proteinMax-binding proteinc-Jun NH2-terminal kinase-associated leucine zipper proteincancer/testis antigen 89human lung cancer oncogene 6 proteinlung cancersrc kinase-associated phosphoprotein 1SKAP-55epididymis secretory sperm binding protein Li 81ppp55src family-associated phosphoprotein 1src kinase-associated phosphoprotein of 55 kDa
Modification date2020031520200313
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000262013, ENST00000357122, 
ENST00000505279, ENST00000509724, 
ENST00000510283, 		ENST00000336915, 
ENST00000584924, 
Fusion gene scores* DoF score20 X 21 X 10=420024 X 12 X 10=2880
# samples 2529
** MAII scorelog2(25/4200*10)=-4.0703893278914
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(29/2880*10)=-3.31194400631474
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: SPAG9 [Title/Abstract] AND SKAP1 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointSPAG9(49156945)-SKAP1(46266862), # samples:3
Anticipated loss of major functional domain due to fusion event.SPAG9-SKAP1 seems lost the major protein functional domain in Hgene partner, which is a essential gene due to the frame-shifted ORF.
SPAG9-SKAP1 seems lost the major protein functional domain in Tgene partner, which is a essential gene due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneSPAG9

GO:0042147

retrograde transport, endosome to Golgi

19056739

TgeneSKAP1

GO:0002821

positive regulation of adaptive immune response

12652296

TgeneSKAP1

GO:0033625

positive regulation of integrin activation

12652296

TgeneSKAP1

GO:0034116

positive regulation of heterotypic cell-cell adhesion

12652296

TgeneSKAP1

GO:0045944

positive regulation of transcription by RNA polymerase II

11909961

TgeneSKAP1

GO:1903039

positive regulation of leukocyte cell-cell adhesion

12652296


check buttonFusion gene breakpoints across SPAG9 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across SKAP1 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4BRCATCGA-EW-A1OV-01ASPAG9chr17

49156945

-SKAP1chr17

46266862

-
ChimerDB4BRCATCGA-EW-A1OVSPAG9chr17

49156944

-SKAP1chr17

46266862

-
ChimerDB4BRCATCGA-EW-A2FS-01ASPAG9chr17

49124736

-SKAP1chr17

46214699

-


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Fusion Gene ORF analysis for SPAG9-SKAP1

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
Frame-shiftENST00000262013ENST00000336915SPAG9chr17

49124736

-SKAP1chr17

46214699

-
Frame-shiftENST00000357122ENST00000336915SPAG9chr17

49124736

-SKAP1chr17

46214699

-
Frame-shiftENST00000505279ENST00000336915SPAG9chr17

49124736

-SKAP1chr17

46214699

-
In-frameENST00000262013ENST00000336915SPAG9chr17

49156945

-SKAP1chr17

46266862

-
In-frameENST00000262013ENST00000336915SPAG9chr17

49156944

-SKAP1chr17

46266862

-
In-frameENST00000262013ENST00000584924SPAG9chr17

49156945

-SKAP1chr17

46266862

-
In-frameENST00000262013ENST00000584924SPAG9chr17

49156944

-SKAP1chr17

46266862

-
In-frameENST00000262013ENST00000584924SPAG9chr17

49124736

-SKAP1chr17

46214699

-
In-frameENST00000357122ENST00000336915SPAG9chr17

49156945

-SKAP1chr17

46266862

-
In-frameENST00000357122ENST00000336915SPAG9chr17

49156944

-SKAP1chr17

46266862

-
In-frameENST00000357122ENST00000584924SPAG9chr17

49156945

-SKAP1chr17

46266862

-
In-frameENST00000357122ENST00000584924SPAG9chr17

49156944

-SKAP1chr17

46266862

-
In-frameENST00000357122ENST00000584924SPAG9chr17

49124736

-SKAP1chr17

46214699

-
In-frameENST00000505279ENST00000336915SPAG9chr17

49156945

-SKAP1chr17

46266862

-
In-frameENST00000505279ENST00000336915SPAG9chr17

49156944

-SKAP1chr17

46266862

-
In-frameENST00000505279ENST00000584924SPAG9chr17

49156945

-SKAP1chr17

46266862

-
In-frameENST00000505279ENST00000584924SPAG9chr17

49156944

-SKAP1chr17

46266862

-
In-frameENST00000505279ENST00000584924SPAG9chr17

49124736

-SKAP1chr17

46214699

-
intron-3CDSENST00000509724ENST00000336915SPAG9chr17

49156945

-SKAP1chr17

46266862

-
intron-3CDSENST00000509724ENST00000336915SPAG9chr17

49156944

-SKAP1chr17

46266862

-
intron-3CDSENST00000509724ENST00000336915SPAG9chr17

49124736

-SKAP1chr17

46214699

-
intron-3CDSENST00000509724ENST00000584924SPAG9chr17

49156945

-SKAP1chr17

46266862

-
intron-3CDSENST00000509724ENST00000584924SPAG9chr17

49156944

-SKAP1chr17

46266862

-
intron-3CDSENST00000509724ENST00000584924SPAG9chr17

49124736

-SKAP1chr17

46214699

-
intron-3CDSENST00000510283ENST00000336915SPAG9chr17

49156945

-SKAP1chr17

46266862

-
intron-3CDSENST00000510283ENST00000336915SPAG9chr17

49156944

-SKAP1chr17

46266862

-
intron-3CDSENST00000510283ENST00000336915SPAG9chr17

49124736

-SKAP1chr17

46214699

-
intron-3CDSENST00000510283ENST00000584924SPAG9chr17

49156945

-SKAP1chr17

46266862

-
intron-3CDSENST00000510283ENST00000584924SPAG9chr17

49156944

-SKAP1chr17

46266862

-
intron-3CDSENST00000510283ENST00000584924SPAG9chr17

49124736

-SKAP1chr17

46214699

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000262013SPAG9chr1749156945-ENST00000336915SKAP1chr1746266862-18176332091432407
ENST00000262013SPAG9chr1749156945-ENST00000584924SKAP1chr1746266862-17316332091432407
ENST00000505279SPAG9chr1749156945-ENST00000336915SKAP1chr1746266862-1686502781301407
ENST00000505279SPAG9chr1749156945-ENST00000584924SKAP1chr1746266862-1600502781301407
ENST00000357122SPAG9chr1749156945-ENST00000336915SKAP1chr1746266862-18176332091432407
ENST00000357122SPAG9chr1749156945-ENST00000584924SKAP1chr1746266862-17316332091432407
ENST00000262013SPAG9chr1749124736-ENST00000584924SKAP1chr1746214699-1199799209835208
ENST00000505279SPAG9chr1749124736-ENST00000584924SKAP1chr1746214699-106866878704208
ENST00000357122SPAG9chr1749124736-ENST00000584924SKAP1chr1746214699-1199799209835208
ENST00000262013SPAG9chr1749156944-ENST00000336915SKAP1chr1746266862-18176332091432407
ENST00000262013SPAG9chr1749156944-ENST00000584924SKAP1chr1746266862-17316332091432407
ENST00000505279SPAG9chr1749156944-ENST00000336915SKAP1chr1746266862-1686502781301407
ENST00000505279SPAG9chr1749156944-ENST00000584924SKAP1chr1746266862-1600502781301407
ENST00000357122SPAG9chr1749156944-ENST00000336915SKAP1chr1746266862-18176332091432407
ENST00000357122SPAG9chr1749156944-ENST00000584924SKAP1chr1746266862-17316332091432407

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000262013ENST00000336915SPAG9chr1749156945-SKAP1chr1746266862-0.0033733040.99662673
ENST00000262013ENST00000584924SPAG9chr1749156945-SKAP1chr1746266862-0.0039802830.9960198
ENST00000505279ENST00000336915SPAG9chr1749156945-SKAP1chr1746266862-0.0031460740.996854
ENST00000505279ENST00000584924SPAG9chr1749156945-SKAP1chr1746266862-0.0037378970.99626213
ENST00000357122ENST00000336915SPAG9chr1749156945-SKAP1chr1746266862-0.0033733040.99662673
ENST00000357122ENST00000584924SPAG9chr1749156945-SKAP1chr1746266862-0.0039802830.9960198
ENST00000262013ENST00000584924SPAG9chr1749124736-SKAP1chr1746214699-0.0029618650.9970381
ENST00000505279ENST00000584924SPAG9chr1749124736-SKAP1chr1746214699-0.0024493980.99755067
ENST00000357122ENST00000584924SPAG9chr1749124736-SKAP1chr1746214699-0.0029618650.9970381
ENST00000262013ENST00000336915SPAG9chr1749156944-SKAP1chr1746266862-0.0033733040.99662673
ENST00000262013ENST00000584924SPAG9chr1749156944-SKAP1chr1746266862-0.0039802830.9960198
ENST00000505279ENST00000336915SPAG9chr1749156944-SKAP1chr1746266862-0.0031460740.996854
ENST00000505279ENST00000584924SPAG9chr1749156944-SKAP1chr1746266862-0.0037378970.99626213
ENST00000357122ENST00000336915SPAG9chr1749156944-SKAP1chr1746266862-0.0033733040.99662673
ENST00000357122ENST00000584924SPAG9chr1749156944-SKAP1chr1746266862-0.0039802830.9960198

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Fusion Genomic Features for SPAG9-SKAP1


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for SPAG9-SKAP1


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr17:49156945/chr17:46266862)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneSPAG9chr17:49124736chr17:46214699ENST00000262013-43066_1661961322.0Coiled coilOntology_term=ECO:0000255
HgeneSPAG9chr17:49124736chr17:46214699ENST00000357122-42966_1661961308.0Coiled coilOntology_term=ECO:0000255
HgeneSPAG9chr17:49124736chr17:46214699ENST00000505279-43066_1661961312.0Coiled coilOntology_term=ECO:0000255
HgeneSPAG9chr17:49124736chr17:46214699ENST00000262013-4307_951961322.0DomainRH1
HgeneSPAG9chr17:49124736chr17:46214699ENST00000357122-4297_951961308.0DomainRH1
HgeneSPAG9chr17:49124736chr17:46214699ENST00000505279-4307_951961312.0DomainRH1
HgeneSPAG9chr17:49156944chr17:46266862ENST00000262013-2307_951411322.0DomainRH1
HgeneSPAG9chr17:49156944chr17:46266862ENST00000357122-2297_951411308.0DomainRH1
HgeneSPAG9chr17:49156944chr17:46266862ENST00000505279-2307_951411312.0DomainRH1
HgeneSPAG9chr17:49156945chr17:46266862ENST00000262013-2307_951411322.0DomainRH1
HgeneSPAG9chr17:49156945chr17:46266862ENST00000357122-2297_951411308.0DomainRH1
HgeneSPAG9chr17:49156945chr17:46266862ENST00000505279-2307_951411312.0DomainRH1
TgeneSKAP1chr17:49156944chr17:46266862ENST00000336915313220_23093448.0Compositional biasNote=Poly-Glu
TgeneSKAP1chr17:49156944chr17:46266862ENST00000584924312220_23093360.0Compositional biasNote=Poly-Glu
TgeneSKAP1chr17:49156945chr17:46266862ENST00000336915313220_23093448.0Compositional biasNote=Poly-Glu
TgeneSKAP1chr17:49156945chr17:46266862ENST00000584924312220_23093360.0Compositional biasNote=Poly-Glu
TgeneSKAP1chr17:49156944chr17:46266862ENST00000336915313107_21093448.0DomainPH
TgeneSKAP1chr17:49156944chr17:46266862ENST00000336915313294_35593448.0DomainSH3
TgeneSKAP1chr17:49156944chr17:46266862ENST00000584924312107_21093360.0DomainPH
TgeneSKAP1chr17:49156944chr17:46266862ENST00000584924312294_35593360.0DomainSH3
TgeneSKAP1chr17:49156945chr17:46266862ENST00000336915313107_21093448.0DomainPH
TgeneSKAP1chr17:49156945chr17:46266862ENST00000336915313294_35593448.0DomainSH3
TgeneSKAP1chr17:49156945chr17:46266862ENST00000584924312107_21093360.0DomainPH
TgeneSKAP1chr17:49156945chr17:46266862ENST00000584924312294_35593360.0DomainSH3

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneSPAG9chr17:49124736chr17:46214699ENST00000262013-430408_5341961322.0Coiled coilOntology_term=ECO:0000269
HgeneSPAG9chr17:49124736chr17:46214699ENST00000262013-430724_7581961322.0Coiled coilOntology_term=ECO:0000255
HgeneSPAG9chr17:49124736chr17:46214699ENST00000357122-429408_5341961308.0Coiled coilOntology_term=ECO:0000269
HgeneSPAG9chr17:49124736chr17:46214699ENST00000357122-429724_7581961308.0Coiled coilOntology_term=ECO:0000255
HgeneSPAG9chr17:49124736chr17:46214699ENST00000505279-430408_5341961312.0Coiled coilOntology_term=ECO:0000269
HgeneSPAG9chr17:49124736chr17:46214699ENST00000505279-430724_7581961312.0Coiled coilOntology_term=ECO:0000255
HgeneSPAG9chr17:49124736chr17:46214699ENST00000510283-127408_53401178.0Coiled coilOntology_term=ECO:0000269
HgeneSPAG9chr17:49124736chr17:46214699ENST00000510283-12766_16601178.0Coiled coilOntology_term=ECO:0000255
HgeneSPAG9chr17:49124736chr17:46214699ENST00000510283-127724_75801178.0Coiled coilOntology_term=ECO:0000255
HgeneSPAG9chr17:49156944chr17:46266862ENST00000262013-230408_5341411322.0Coiled coilOntology_term=ECO:0000269
HgeneSPAG9chr17:49156944chr17:46266862ENST00000262013-23066_1661411322.0Coiled coilOntology_term=ECO:0000255
HgeneSPAG9chr17:49156944chr17:46266862ENST00000262013-230724_7581411322.0Coiled coilOntology_term=ECO:0000255
HgeneSPAG9chr17:49156944chr17:46266862ENST00000357122-229408_5341411308.0Coiled coilOntology_term=ECO:0000269
HgeneSPAG9chr17:49156944chr17:46266862ENST00000357122-22966_1661411308.0Coiled coilOntology_term=ECO:0000255
HgeneSPAG9chr17:49156944chr17:46266862ENST00000357122-229724_7581411308.0Coiled coilOntology_term=ECO:0000255
HgeneSPAG9chr17:49156944chr17:46266862ENST00000505279-230408_5341411312.0Coiled coilOntology_term=ECO:0000269
HgeneSPAG9chr17:49156944chr17:46266862ENST00000505279-23066_1661411312.0Coiled coilOntology_term=ECO:0000255
HgeneSPAG9chr17:49156944chr17:46266862ENST00000505279-230724_7581411312.0Coiled coilOntology_term=ECO:0000255
HgeneSPAG9chr17:49156944chr17:46266862ENST00000510283-127408_53401178.0Coiled coilOntology_term=ECO:0000269
HgeneSPAG9chr17:49156944chr17:46266862ENST00000510283-12766_16601178.0Coiled coilOntology_term=ECO:0000255
HgeneSPAG9chr17:49156944chr17:46266862ENST00000510283-127724_75801178.0Coiled coilOntology_term=ECO:0000255
HgeneSPAG9chr17:49156945chr17:46266862ENST00000262013-230408_5341411322.0Coiled coilOntology_term=ECO:0000269
HgeneSPAG9chr17:49156945chr17:46266862ENST00000262013-23066_1661411322.0Coiled coilOntology_term=ECO:0000255
HgeneSPAG9chr17:49156945chr17:46266862ENST00000262013-230724_7581411322.0Coiled coilOntology_term=ECO:0000255
HgeneSPAG9chr17:49156945chr17:46266862ENST00000357122-229408_5341411308.0Coiled coilOntology_term=ECO:0000269
HgeneSPAG9chr17:49156945chr17:46266862ENST00000357122-22966_1661411308.0Coiled coilOntology_term=ECO:0000255
HgeneSPAG9chr17:49156945chr17:46266862ENST00000357122-229724_7581411308.0Coiled coilOntology_term=ECO:0000255
HgeneSPAG9chr17:49156945chr17:46266862ENST00000505279-230408_5341411312.0Coiled coilOntology_term=ECO:0000269
HgeneSPAG9chr17:49156945chr17:46266862ENST00000505279-23066_1661411312.0Coiled coilOntology_term=ECO:0000255
HgeneSPAG9chr17:49156945chr17:46266862ENST00000505279-230724_7581411312.0Coiled coilOntology_term=ECO:0000255
HgeneSPAG9chr17:49156945chr17:46266862ENST00000510283-127408_53401178.0Coiled coilOntology_term=ECO:0000269
HgeneSPAG9chr17:49156945chr17:46266862ENST00000510283-12766_16601178.0Coiled coilOntology_term=ECO:0000255
HgeneSPAG9chr17:49156945chr17:46266862ENST00000510283-127724_75801178.0Coiled coilOntology_term=ECO:0000255
HgeneSPAG9chr17:49124736chr17:46214699ENST00000262013-430500_5711961322.0DomainRH2
HgeneSPAG9chr17:49124736chr17:46214699ENST00000357122-429500_5711961308.0DomainRH2
HgeneSPAG9chr17:49124736chr17:46214699ENST00000505279-430500_5711961312.0DomainRH2
HgeneSPAG9chr17:49124736chr17:46214699ENST00000510283-127500_57101178.0DomainRH2
HgeneSPAG9chr17:49124736chr17:46214699ENST00000510283-1277_9501178.0DomainRH1
HgeneSPAG9chr17:49156944chr17:46266862ENST00000262013-230500_5711411322.0DomainRH2
HgeneSPAG9chr17:49156944chr17:46266862ENST00000357122-229500_5711411308.0DomainRH2
HgeneSPAG9chr17:49156944chr17:46266862ENST00000505279-230500_5711411312.0DomainRH2
HgeneSPAG9chr17:49156944chr17:46266862ENST00000510283-127500_57101178.0DomainRH2
HgeneSPAG9chr17:49156944chr17:46266862ENST00000510283-1277_9501178.0DomainRH1
HgeneSPAG9chr17:49156945chr17:46266862ENST00000262013-230500_5711411322.0DomainRH2
HgeneSPAG9chr17:49156945chr17:46266862ENST00000357122-229500_5711411308.0DomainRH2
HgeneSPAG9chr17:49156945chr17:46266862ENST00000505279-230500_5711411312.0DomainRH2
HgeneSPAG9chr17:49156945chr17:46266862ENST00000510283-127500_57101178.0DomainRH2
HgeneSPAG9chr17:49156945chr17:46266862ENST00000510283-1277_9501178.0DomainRH1
TgeneSKAP1chr17:49124736chr17:46214699ENST000003369151013220_230326448.0Compositional biasNote=Poly-Glu
TgeneSKAP1chr17:49124736chr17:46214699ENST000005849241012220_230326360.0Compositional biasNote=Poly-Glu
TgeneSKAP1chr17:49124736chr17:46214699ENST000003369151013107_210326448.0DomainPH
TgeneSKAP1chr17:49124736chr17:46214699ENST000003369151013294_355326448.0DomainSH3
TgeneSKAP1chr17:49124736chr17:46214699ENST000005849241012107_210326360.0DomainPH
TgeneSKAP1chr17:49124736chr17:46214699ENST000005849241012294_355326360.0DomainSH3


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Fusion Gene Sequence for SPAG9-SKAP1


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>85465_85465_1_SPAG9-SKAP1_SPAG9_chr17_49124736_ENST00000262013_SKAP1_chr17_46214699_ENST00000584924_length(transcript)=1199nt_BP=799nt
AGTTGGTGCAGCGGCGGTTGGGGTGAGAGCGCCTACGCCACCCCTCCCCTCCTCCGGCCCCGGCCCCCACCCCGCCGGGCCCAGCCCCAG
CCCCGGCCCGGGCTCCAGCCCTAGTACCCGTCCCAGCCCGAGTCGGGTCCGTCCCGTGCGGGCAGGTGCCGCCCCTCTGCCGGCGACGCC
CCGGGCCGCCCGCCCGTCCGCTTGCCACCATGGAGCTGGAGGACGGTGTGGTGTATCAGGAGGAGCCCGGCGGCTCCGGGGCCGTGATGT
CGGAGCGGGTGTCCGGCCTGGCCGGCTCCATCTACCGCGAGTTCGAGCGGCTTATCGGGCGCTATGACGAGGAGGTGGTCAAAGAGCTGA
TGCCGCTGGTGGTGGCTGTGCTGGAGAACCTGGACTCGGTGTTCGCGCAGGACCAGGAGCACCAGGTGGAGCTGGAGCTGCTGCGGGACG
ACAACGAGCAGCTCATCACCCAGTACGAGCGGGAGAAGGCGCTGCGCAAGCACGCTGAGGAGAAATTCATTGAATTTGAAGACTCTCAAG
AACAGGAAAAAAAGGACTTACAGACCCGAGTGGAATCTTTAGAATCTCAAACAAGACAACTTGAGCTGAAAGCGAAAAACTATGCTGACC
AGATTAGCAGACTTGAAGAAAGAGAAGCAGAACTGAAGAAGGAATATAATGCATTACATCAAAGACACACTGAGATGATCCATAATTATA
TGGAACATTTAGAAAGAACAAAACTTCATCAGCTCTCAGGGAGTGATCAACTAGAATCCACAGCTCATAGTAGAATTAGGAGTATAACAT
GTATGGCTGGTGGGTGGGAGAACTGAACAGCCTCGTTGGGATTGTTCCAAAGGAGTATCTCACCACTGCCTTTGAAGTGGAAGAAAGATG
AAACCCAGGTATCAGAACCATGGCCAATGAACTGCCTAATAGTTGAGTGGAACTTGTGGGCCACTACTTTGTTTCTCTGAAAGATGAGAG
TTGCCAGTGAAGTAGCTTTTCTTCATTTCTCATACTAATGCTAGTGATTCACCACTGATGGAAAGAAAATGCCTCTGGAATTGTTTTTTT
CTTAAATTTGGGGACAGTGTCACTTAGGATAAGGTTCAACTAATAGCAACATAAAATCTAAACTAAAAATGACTTAATTAACACAGAAAG

>85465_85465_1_SPAG9-SKAP1_SPAG9_chr17_49124736_ENST00000262013_SKAP1_chr17_46214699_ENST00000584924_length(amino acids)=208AA_BP=
MELEDGVVYQEEPGGSGAVMSERVSGLAGSIYREFERLIGRYDEEVVKELMPLVVAVLENLDSVFAQDQEHQVELELLRDDNEQLITQYE
REKALRKHAEEKFIEFEDSQEQEKKDLQTRVESLESQTRQLELKAKNYADQISRLEEREAELKKEYNALHQRHTEMIHNYMEHLERTKLH

--------------------------------------------------------------
>85465_85465_2_SPAG9-SKAP1_SPAG9_chr17_49124736_ENST00000357122_SKAP1_chr17_46214699_ENST00000584924_length(transcript)=1199nt_BP=799nt
AGTTGGTGCAGCGGCGGTTGGGGTGAGAGCGCCTACGCCACCCCTCCCCTCCTCCGGCCCCGGCCCCCACCCCGCCGGGCCCAGCCCCAG
CCCCGGCCCGGGCTCCAGCCCTAGTACCCGTCCCAGCCCGAGTCGGGTCCGTCCCGTGCGGGCAGGTGCCGCCCCTCTGCCGGCGACGCC
CCGGGCCGCCCGCCCGTCCGCTTGCCACCATGGAGCTGGAGGACGGTGTGGTGTATCAGGAGGAGCCCGGCGGCTCCGGGGCCGTGATGT
CGGAGCGGGTGTCCGGCCTGGCCGGCTCCATCTACCGCGAGTTCGAGCGGCTTATCGGGCGCTATGACGAGGAGGTGGTCAAAGAGCTGA
TGCCGCTGGTGGTGGCTGTGCTGGAGAACCTGGACTCGGTGTTCGCGCAGGACCAGGAGCACCAGGTGGAGCTGGAGCTGCTGCGGGACG
ACAACGAGCAGCTCATCACCCAGTACGAGCGGGAGAAGGCGCTGCGCAAGCACGCTGAGGAGAAATTCATTGAATTTGAAGACTCTCAAG
AACAGGAAAAAAAGGACTTACAGACCCGAGTGGAATCTTTAGAATCTCAAACAAGACAACTTGAGCTGAAAGCGAAAAACTATGCTGACC
AGATTAGCAGACTTGAAGAAAGAGAAGCAGAACTGAAGAAGGAATATAATGCATTACATCAAAGACACACTGAGATGATCCATAATTATA
TGGAACATTTAGAAAGAACAAAACTTCATCAGCTCTCAGGGAGTGATCAACTAGAATCCACAGCTCATAGTAGAATTAGGAGTATAACAT
GTATGGCTGGTGGGTGGGAGAACTGAACAGCCTCGTTGGGATTGTTCCAAAGGAGTATCTCACCACTGCCTTTGAAGTGGAAGAAAGATG
AAACCCAGGTATCAGAACCATGGCCAATGAACTGCCTAATAGTTGAGTGGAACTTGTGGGCCACTACTTTGTTTCTCTGAAAGATGAGAG
TTGCCAGTGAAGTAGCTTTTCTTCATTTCTCATACTAATGCTAGTGATTCACCACTGATGGAAAGAAAATGCCTCTGGAATTGTTTTTTT
CTTAAATTTGGGGACAGTGTCACTTAGGATAAGGTTCAACTAATAGCAACATAAAATCTAAACTAAAAATGACTTAATTAACACAGAAAG

>85465_85465_2_SPAG9-SKAP1_SPAG9_chr17_49124736_ENST00000357122_SKAP1_chr17_46214699_ENST00000584924_length(amino acids)=208AA_BP=
MELEDGVVYQEEPGGSGAVMSERVSGLAGSIYREFERLIGRYDEEVVKELMPLVVAVLENLDSVFAQDQEHQVELELLRDDNEQLITQYE
REKALRKHAEEKFIEFEDSQEQEKKDLQTRVESLESQTRQLELKAKNYADQISRLEEREAELKKEYNALHQRHTEMIHNYMEHLERTKLH

--------------------------------------------------------------
>85465_85465_3_SPAG9-SKAP1_SPAG9_chr17_49124736_ENST00000505279_SKAP1_chr17_46214699_ENST00000584924_length(transcript)=1068nt_BP=668nt
GTCGGGTCCGTCCCGTGCGGGCAGGTGCCGCCCCTCTGCCGGCGACGCCCCGGGCCGCCCGCCCGTCCGCTTGCCACCATGGAGCTGGAG
GACGGTGTGGTGTATCAGGAGGAGCCCGGCGGCTCCGGGGCCGTGATGTCGGAGCGGGTGTCCGGCCTGGCCGGCTCCATCTACCGCGAG
TTCGAGCGGCTTATCGGGCGCTATGACGAGGAGGTGGTCAAAGAGCTGATGCCGCTGGTGGTGGCTGTGCTGGAGAACCTGGACTCGGTG
TTCGCGCAGGACCAGGAGCACCAGGTGGAGCTGGAGCTGCTGCGGGACGACAACGAGCAGCTCATCACCCAGTACGAGCGGGAGAAGGCG
CTGCGCAAGCACGCTGAGGAGAAATTCATTGAATTTGAAGACTCTCAAGAACAGGAAAAAAAGGACTTACAGACCCGAGTGGAATCTTTA
GAATCTCAAACAAGACAACTTGAGCTGAAAGCGAAAAACTATGCTGACCAGATTAGCAGACTTGAAGAAAGAGAAGCAGAACTGAAGAAG
GAATATAATGCATTACATCAAAGACACACTGAGATGATCCATAATTATATGGAACATTTAGAAAGAACAAAACTTCATCAGCTCTCAGGG
AGTGATCAACTAGAATCCACAGCTCATAGTAGAATTAGGAGTATAACATGTATGGCTGGTGGGTGGGAGAACTGAACAGCCTCGTTGGGA
TTGTTCCAAAGGAGTATCTCACCACTGCCTTTGAAGTGGAAGAAAGATGAAACCCAGGTATCAGAACCATGGCCAATGAACTGCCTAATA
GTTGAGTGGAACTTGTGGGCCACTACTTTGTTTCTCTGAAAGATGAGAGTTGCCAGTGAAGTAGCTTTTCTTCATTTCTCATACTAATGC
TAGTGATTCACCACTGATGGAAAGAAAATGCCTCTGGAATTGTTTTTTTCTTAAATTTGGGGACAGTGTCACTTAGGATAAGGTTCAACT

>85465_85465_3_SPAG9-SKAP1_SPAG9_chr17_49124736_ENST00000505279_SKAP1_chr17_46214699_ENST00000584924_length(amino acids)=208AA_BP=
MELEDGVVYQEEPGGSGAVMSERVSGLAGSIYREFERLIGRYDEEVVKELMPLVVAVLENLDSVFAQDQEHQVELELLRDDNEQLITQYE
REKALRKHAEEKFIEFEDSQEQEKKDLQTRVESLESQTRQLELKAKNYADQISRLEEREAELKKEYNALHQRHTEMIHNYMEHLERTKLH

--------------------------------------------------------------
>85465_85465_4_SPAG9-SKAP1_SPAG9_chr17_49156944_ENST00000262013_SKAP1_chr17_46266862_ENST00000336915_length(transcript)=1817nt_BP=633nt
AGTTGGTGCAGCGGCGGTTGGGGTGAGAGCGCCTACGCCACCCCTCCCCTCCTCCGGCCCCGGCCCCCACCCCGCCGGGCCCAGCCCCAG
CCCCGGCCCGGGCTCCAGCCCTAGTACCCGTCCCAGCCCGAGTCGGGTCCGTCCCGTGCGGGCAGGTGCCGCCCCTCTGCCGGCGACGCC
CCGGGCCGCCCGCCCGTCCGCTTGCCACCATGGAGCTGGAGGACGGTGTGGTGTATCAGGAGGAGCCCGGCGGCTCCGGGGCCGTGATGT
CGGAGCGGGTGTCCGGCCTGGCCGGCTCCATCTACCGCGAGTTCGAGCGGCTTATCGGGCGCTATGACGAGGAGGTGGTCAAAGAGCTGA
TGCCGCTGGTGGTGGCTGTGCTGGAGAACCTGGACTCGGTGTTCGCGCAGGACCAGGAGCACCAGGTGGAGCTGGAGCTGCTGCGGGACG
ACAACGAGCAGCTCATCACCCAGTACGAGCGGGAGAAGGCGCTGCGCAAGCACGCTGAGGAGAAATTCATTGAATTTGAAGACTCTCAAG
AACAGGAAAAAAAGGACTTACAGACCCGAGTGGAATCTTTAGAATCTCAAACAAGACAACTTGAGCTGAAAGCGAAAAACTATGCTGACC
AGAGAATGGAAGACATCGTAAAAGGAGCTCAAGAACTTGATAACGTAATCAAGCAAGGATACTTGGAGAAGAAAAGCAAAGATCATAGTT
TCTTTGGATCGGAGTGGCAGAAGCGATGGTGTGTTGTCAGCAGAGGTCTCTTCTACTACTATGCTAATGAGAAGAGCAAGCAGCCCAAAG
GGACCTTCCTCATTAAGGGCTACGGTGTACGGATGGCCCCCCACCTGCGAAGAGATTCCAAGAAAGAATCCTGCTTTGAACTGACCTCCC
AGGATAGGCGCAGCTATGAGTTTACAGCTACTAGTCCAGCAGAAGCCAGAGACTGGGTGGATCAAATAAGTTTCTTGTTAAAGGATCTGA
GCTCCTTAACCATTCCATATGAAGAGGATGAGGAGGAAGAAGAAAAAGAAGAGACATATGATGATATTGATGGTTTTGACTCCCCAAGTT
GTGGTTCCCAGTGCAGACCCACTATCTTGCCTGGGAGTGTGGGGATAAAAGAGCCTACAGAGGAGAAAGAAGAAGAAGATATTTATGAAG
TCTTGCCAGATGAAGAGCATGATCTAGAAGAGGATGAGAGTGGCACTCGACGAAAAGGAGTAGACTATGCCAGTTACTACCAGGGCCTAT
GGGATTGCCATGGTGACCAGCCAGATGAACTGTCCTTCCAACGGGGTGACCTCATCCGTATTCTGAGCAAGGAGTATAACATGTATGGCT
GGTGGGTGGGAGAACTGAACAGCCTCGTTGGGATTGTTCCAAAGGAGTATCTCACCACTGCCTTTGAAGTGGAAGAAAGATGAAACCCAG
GAAATATATTCTTCCCTCTCTCCTGCCTTTATGAGGAAACTGATCATCAAAAGTTCCCACTCCCTACTTCTGCCACCCCACCAACGCCTT
GGACTCCTCTCTTTGCTGAAGAGACCCAAGTCTCTTGACACCTCAGAGTGACTGTAAGCTACCAGTAAGACAAGTGGGAAGAGGCACGTT
CATCAAACCTGTTACTAAACCAGCCTAGTCATAGCTCATCCCCATCTCTAAATGTGTCCACACAACCACATCTGCCTTTTCCACAAGCTT
TTCACAAAGAAGGTGAGAGAGAAGGAAACCTTGGGAGGAGGACATTACTGGTTGTTCTGGCTGGTTTGAAAAGCACAAATAAACTTGGGA

>85465_85465_4_SPAG9-SKAP1_SPAG9_chr17_49156944_ENST00000262013_SKAP1_chr17_46266862_ENST00000336915_length(amino acids)=407AA_BP=142
MELEDGVVYQEEPGGSGAVMSERVSGLAGSIYREFERLIGRYDEEVVKELMPLVVAVLENLDSVFAQDQEHQVELELLRDDNEQLITQYE
REKALRKHAEEKFIEFEDSQEQEKKDLQTRVESLESQTRQLELKAKNYADQRMEDIVKGAQELDNVIKQGYLEKKSKDHSFFGSEWQKRW
CVVSRGLFYYYANEKSKQPKGTFLIKGYGVRMAPHLRRDSKKESCFELTSQDRRSYEFTATSPAEARDWVDQISFLLKDLSSLTIPYEED
EEEEEKEETYDDIDGFDSPSCGSQCRPTILPGSVGIKEPTEEKEEEDIYEVLPDEEHDLEEDESGTRRKGVDYASYYQGLWDCHGDQPDE

--------------------------------------------------------------
>85465_85465_5_SPAG9-SKAP1_SPAG9_chr17_49156944_ENST00000262013_SKAP1_chr17_46266862_ENST00000584924_length(transcript)=1731nt_BP=633nt
AGTTGGTGCAGCGGCGGTTGGGGTGAGAGCGCCTACGCCACCCCTCCCCTCCTCCGGCCCCGGCCCCCACCCCGCCGGGCCCAGCCCCAG
CCCCGGCCCGGGCTCCAGCCCTAGTACCCGTCCCAGCCCGAGTCGGGTCCGTCCCGTGCGGGCAGGTGCCGCCCCTCTGCCGGCGACGCC
CCGGGCCGCCCGCCCGTCCGCTTGCCACCATGGAGCTGGAGGACGGTGTGGTGTATCAGGAGGAGCCCGGCGGCTCCGGGGCCGTGATGT
CGGAGCGGGTGTCCGGCCTGGCCGGCTCCATCTACCGCGAGTTCGAGCGGCTTATCGGGCGCTATGACGAGGAGGTGGTCAAAGAGCTGA
TGCCGCTGGTGGTGGCTGTGCTGGAGAACCTGGACTCGGTGTTCGCGCAGGACCAGGAGCACCAGGTGGAGCTGGAGCTGCTGCGGGACG
ACAACGAGCAGCTCATCACCCAGTACGAGCGGGAGAAGGCGCTGCGCAAGCACGCTGAGGAGAAATTCATTGAATTTGAAGACTCTCAAG
AACAGGAAAAAAAGGACTTACAGACCCGAGTGGAATCTTTAGAATCTCAAACAAGACAACTTGAGCTGAAAGCGAAAAACTATGCTGACC
AGAGAATGGAAGACATCGTAAAAGGAGCTCAAGAACTTGATAACGTAATCAAGCAAGGATACTTGGAGAAGAAAAGCAAAGATCATAGTT
TCTTTGGATCGGAGTGGCAGAAGCGATGGTGTGTTGTCAGCAGAGGTCTCTTCTACTACTATGCTAATGAGAAGAGCAAGCAGCCCAAAG
GGACCTTCCTCATTAAGGGCTACGGTGTACGGATGGCCCCCCACCTGCGAAGAGATTCCAAGAAAGAATCCTGCTTTGAACTGACCTCCC
AGGATAGGCGCAGCTATGAGTTTACAGCTACTAGTCCAGCAGAAGCCAGAGACTGGGTGGATCAAATAAGTTTCTTGTTAAAGGATCTGA
GCTCCTTAACCATTCCATATGAAGAGGATGAGGAGGAAGAAGAAAAAGAAGAGACATATGATGATATTGATGGTTTTGACTCCCCAAGTT
GTGGTTCCCAGTGCAGACCCACTATCTTGCCTGGGAGTGTGGGGATAAAAGAGCCTACAGAGGAGAAAGAAGAAGAAGATATTTATGAAG
TCTTGCCAGATGAAGAGCATGATCTAGAAGAGGATGAGAGTGGCACTCGACGAAAAGGAGTAGACTATGCCAGTTACTACCAGGGCCTAT
GGGATTGCCATGGTGACCAGCCAGATGAACTGTCCTTCCAACGGGGTGACCTCATCCGTATTCTGAGCAAGGAGTATAACATGTATGGCT
GGTGGGTGGGAGAACTGAACAGCCTCGTTGGGATTGTTCCAAAGGAGTATCTCACCACTGCCTTTGAAGTGGAAGAAAGATGAAACCCAG
GTATCAGAACCATGGCCAATGAACTGCCTAATAGTTGAGTGGAACTTGTGGGCCACTACTTTGTTTCTCTGAAAGATGAGAGTTGCCAGT
GAAGTAGCTTTTCTTCATTTCTCATACTAATGCTAGTGATTCACCACTGATGGAAAGAAAATGCCTCTGGAATTGTTTTTTTCTTAAATT
TGGGGACAGTGTCACTTAGGATAAGGTTCAACTAATAGCAACATAAAATCTAAACTAAAAATGACTTAATTAACACAGAAAGCCAGGCAC

>85465_85465_5_SPAG9-SKAP1_SPAG9_chr17_49156944_ENST00000262013_SKAP1_chr17_46266862_ENST00000584924_length(amino acids)=407AA_BP=142
MELEDGVVYQEEPGGSGAVMSERVSGLAGSIYREFERLIGRYDEEVVKELMPLVVAVLENLDSVFAQDQEHQVELELLRDDNEQLITQYE
REKALRKHAEEKFIEFEDSQEQEKKDLQTRVESLESQTRQLELKAKNYADQRMEDIVKGAQELDNVIKQGYLEKKSKDHSFFGSEWQKRW
CVVSRGLFYYYANEKSKQPKGTFLIKGYGVRMAPHLRRDSKKESCFELTSQDRRSYEFTATSPAEARDWVDQISFLLKDLSSLTIPYEED
EEEEEKEETYDDIDGFDSPSCGSQCRPTILPGSVGIKEPTEEKEEEDIYEVLPDEEHDLEEDESGTRRKGVDYASYYQGLWDCHGDQPDE

--------------------------------------------------------------
>85465_85465_6_SPAG9-SKAP1_SPAG9_chr17_49156944_ENST00000357122_SKAP1_chr17_46266862_ENST00000336915_length(transcript)=1817nt_BP=633nt
AGTTGGTGCAGCGGCGGTTGGGGTGAGAGCGCCTACGCCACCCCTCCCCTCCTCCGGCCCCGGCCCCCACCCCGCCGGGCCCAGCCCCAG
CCCCGGCCCGGGCTCCAGCCCTAGTACCCGTCCCAGCCCGAGTCGGGTCCGTCCCGTGCGGGCAGGTGCCGCCCCTCTGCCGGCGACGCC
CCGGGCCGCCCGCCCGTCCGCTTGCCACCATGGAGCTGGAGGACGGTGTGGTGTATCAGGAGGAGCCCGGCGGCTCCGGGGCCGTGATGT
CGGAGCGGGTGTCCGGCCTGGCCGGCTCCATCTACCGCGAGTTCGAGCGGCTTATCGGGCGCTATGACGAGGAGGTGGTCAAAGAGCTGA
TGCCGCTGGTGGTGGCTGTGCTGGAGAACCTGGACTCGGTGTTCGCGCAGGACCAGGAGCACCAGGTGGAGCTGGAGCTGCTGCGGGACG
ACAACGAGCAGCTCATCACCCAGTACGAGCGGGAGAAGGCGCTGCGCAAGCACGCTGAGGAGAAATTCATTGAATTTGAAGACTCTCAAG
AACAGGAAAAAAAGGACTTACAGACCCGAGTGGAATCTTTAGAATCTCAAACAAGACAACTTGAGCTGAAAGCGAAAAACTATGCTGACC
AGAGAATGGAAGACATCGTAAAAGGAGCTCAAGAACTTGATAACGTAATCAAGCAAGGATACTTGGAGAAGAAAAGCAAAGATCATAGTT
TCTTTGGATCGGAGTGGCAGAAGCGATGGTGTGTTGTCAGCAGAGGTCTCTTCTACTACTATGCTAATGAGAAGAGCAAGCAGCCCAAAG
GGACCTTCCTCATTAAGGGCTACGGTGTACGGATGGCCCCCCACCTGCGAAGAGATTCCAAGAAAGAATCCTGCTTTGAACTGACCTCCC
AGGATAGGCGCAGCTATGAGTTTACAGCTACTAGTCCAGCAGAAGCCAGAGACTGGGTGGATCAAATAAGTTTCTTGTTAAAGGATCTGA
GCTCCTTAACCATTCCATATGAAGAGGATGAGGAGGAAGAAGAAAAAGAAGAGACATATGATGATATTGATGGTTTTGACTCCCCAAGTT
GTGGTTCCCAGTGCAGACCCACTATCTTGCCTGGGAGTGTGGGGATAAAAGAGCCTACAGAGGAGAAAGAAGAAGAAGATATTTATGAAG
TCTTGCCAGATGAAGAGCATGATCTAGAAGAGGATGAGAGTGGCACTCGACGAAAAGGAGTAGACTATGCCAGTTACTACCAGGGCCTAT
GGGATTGCCATGGTGACCAGCCAGATGAACTGTCCTTCCAACGGGGTGACCTCATCCGTATTCTGAGCAAGGAGTATAACATGTATGGCT
GGTGGGTGGGAGAACTGAACAGCCTCGTTGGGATTGTTCCAAAGGAGTATCTCACCACTGCCTTTGAAGTGGAAGAAAGATGAAACCCAG
GAAATATATTCTTCCCTCTCTCCTGCCTTTATGAGGAAACTGATCATCAAAAGTTCCCACTCCCTACTTCTGCCACCCCACCAACGCCTT
GGACTCCTCTCTTTGCTGAAGAGACCCAAGTCTCTTGACACCTCAGAGTGACTGTAAGCTACCAGTAAGACAAGTGGGAAGAGGCACGTT
CATCAAACCTGTTACTAAACCAGCCTAGTCATAGCTCATCCCCATCTCTAAATGTGTCCACACAACCACATCTGCCTTTTCCACAAGCTT
TTCACAAAGAAGGTGAGAGAGAAGGAAACCTTGGGAGGAGGACATTACTGGTTGTTCTGGCTGGTTTGAAAAGCACAAATAAACTTGGGA

>85465_85465_6_SPAG9-SKAP1_SPAG9_chr17_49156944_ENST00000357122_SKAP1_chr17_46266862_ENST00000336915_length(amino acids)=407AA_BP=142
MELEDGVVYQEEPGGSGAVMSERVSGLAGSIYREFERLIGRYDEEVVKELMPLVVAVLENLDSVFAQDQEHQVELELLRDDNEQLITQYE
REKALRKHAEEKFIEFEDSQEQEKKDLQTRVESLESQTRQLELKAKNYADQRMEDIVKGAQELDNVIKQGYLEKKSKDHSFFGSEWQKRW
CVVSRGLFYYYANEKSKQPKGTFLIKGYGVRMAPHLRRDSKKESCFELTSQDRRSYEFTATSPAEARDWVDQISFLLKDLSSLTIPYEED
EEEEEKEETYDDIDGFDSPSCGSQCRPTILPGSVGIKEPTEEKEEEDIYEVLPDEEHDLEEDESGTRRKGVDYASYYQGLWDCHGDQPDE

--------------------------------------------------------------
>85465_85465_7_SPAG9-SKAP1_SPAG9_chr17_49156944_ENST00000357122_SKAP1_chr17_46266862_ENST00000584924_length(transcript)=1731nt_BP=633nt
AGTTGGTGCAGCGGCGGTTGGGGTGAGAGCGCCTACGCCACCCCTCCCCTCCTCCGGCCCCGGCCCCCACCCCGCCGGGCCCAGCCCCAG
CCCCGGCCCGGGCTCCAGCCCTAGTACCCGTCCCAGCCCGAGTCGGGTCCGTCCCGTGCGGGCAGGTGCCGCCCCTCTGCCGGCGACGCC
CCGGGCCGCCCGCCCGTCCGCTTGCCACCATGGAGCTGGAGGACGGTGTGGTGTATCAGGAGGAGCCCGGCGGCTCCGGGGCCGTGATGT
CGGAGCGGGTGTCCGGCCTGGCCGGCTCCATCTACCGCGAGTTCGAGCGGCTTATCGGGCGCTATGACGAGGAGGTGGTCAAAGAGCTGA
TGCCGCTGGTGGTGGCTGTGCTGGAGAACCTGGACTCGGTGTTCGCGCAGGACCAGGAGCACCAGGTGGAGCTGGAGCTGCTGCGGGACG
ACAACGAGCAGCTCATCACCCAGTACGAGCGGGAGAAGGCGCTGCGCAAGCACGCTGAGGAGAAATTCATTGAATTTGAAGACTCTCAAG
AACAGGAAAAAAAGGACTTACAGACCCGAGTGGAATCTTTAGAATCTCAAACAAGACAACTTGAGCTGAAAGCGAAAAACTATGCTGACC
AGAGAATGGAAGACATCGTAAAAGGAGCTCAAGAACTTGATAACGTAATCAAGCAAGGATACTTGGAGAAGAAAAGCAAAGATCATAGTT
TCTTTGGATCGGAGTGGCAGAAGCGATGGTGTGTTGTCAGCAGAGGTCTCTTCTACTACTATGCTAATGAGAAGAGCAAGCAGCCCAAAG
GGACCTTCCTCATTAAGGGCTACGGTGTACGGATGGCCCCCCACCTGCGAAGAGATTCCAAGAAAGAATCCTGCTTTGAACTGACCTCCC
AGGATAGGCGCAGCTATGAGTTTACAGCTACTAGTCCAGCAGAAGCCAGAGACTGGGTGGATCAAATAAGTTTCTTGTTAAAGGATCTGA
GCTCCTTAACCATTCCATATGAAGAGGATGAGGAGGAAGAAGAAAAAGAAGAGACATATGATGATATTGATGGTTTTGACTCCCCAAGTT
GTGGTTCCCAGTGCAGACCCACTATCTTGCCTGGGAGTGTGGGGATAAAAGAGCCTACAGAGGAGAAAGAAGAAGAAGATATTTATGAAG
TCTTGCCAGATGAAGAGCATGATCTAGAAGAGGATGAGAGTGGCACTCGACGAAAAGGAGTAGACTATGCCAGTTACTACCAGGGCCTAT
GGGATTGCCATGGTGACCAGCCAGATGAACTGTCCTTCCAACGGGGTGACCTCATCCGTATTCTGAGCAAGGAGTATAACATGTATGGCT
GGTGGGTGGGAGAACTGAACAGCCTCGTTGGGATTGTTCCAAAGGAGTATCTCACCACTGCCTTTGAAGTGGAAGAAAGATGAAACCCAG
GTATCAGAACCATGGCCAATGAACTGCCTAATAGTTGAGTGGAACTTGTGGGCCACTACTTTGTTTCTCTGAAAGATGAGAGTTGCCAGT
GAAGTAGCTTTTCTTCATTTCTCATACTAATGCTAGTGATTCACCACTGATGGAAAGAAAATGCCTCTGGAATTGTTTTTTTCTTAAATT
TGGGGACAGTGTCACTTAGGATAAGGTTCAACTAATAGCAACATAAAATCTAAACTAAAAATGACTTAATTAACACAGAAAGCCAGGCAC

>85465_85465_7_SPAG9-SKAP1_SPAG9_chr17_49156944_ENST00000357122_SKAP1_chr17_46266862_ENST00000584924_length(amino acids)=407AA_BP=142
MELEDGVVYQEEPGGSGAVMSERVSGLAGSIYREFERLIGRYDEEVVKELMPLVVAVLENLDSVFAQDQEHQVELELLRDDNEQLITQYE
REKALRKHAEEKFIEFEDSQEQEKKDLQTRVESLESQTRQLELKAKNYADQRMEDIVKGAQELDNVIKQGYLEKKSKDHSFFGSEWQKRW
CVVSRGLFYYYANEKSKQPKGTFLIKGYGVRMAPHLRRDSKKESCFELTSQDRRSYEFTATSPAEARDWVDQISFLLKDLSSLTIPYEED
EEEEEKEETYDDIDGFDSPSCGSQCRPTILPGSVGIKEPTEEKEEEDIYEVLPDEEHDLEEDESGTRRKGVDYASYYQGLWDCHGDQPDE

--------------------------------------------------------------
>85465_85465_8_SPAG9-SKAP1_SPAG9_chr17_49156944_ENST00000505279_SKAP1_chr17_46266862_ENST00000336915_length(transcript)=1686nt_BP=502nt
GTCGGGTCCGTCCCGTGCGGGCAGGTGCCGCCCCTCTGCCGGCGACGCCCCGGGCCGCCCGCCCGTCCGCTTGCCACCATGGAGCTGGAG
GACGGTGTGGTGTATCAGGAGGAGCCCGGCGGCTCCGGGGCCGTGATGTCGGAGCGGGTGTCCGGCCTGGCCGGCTCCATCTACCGCGAG
TTCGAGCGGCTTATCGGGCGCTATGACGAGGAGGTGGTCAAAGAGCTGATGCCGCTGGTGGTGGCTGTGCTGGAGAACCTGGACTCGGTG
TTCGCGCAGGACCAGGAGCACCAGGTGGAGCTGGAGCTGCTGCGGGACGACAACGAGCAGCTCATCACCCAGTACGAGCGGGAGAAGGCG
CTGCGCAAGCACGCTGAGGAGAAATTCATTGAATTTGAAGACTCTCAAGAACAGGAAAAAAAGGACTTACAGACCCGAGTGGAATCTTTA
GAATCTCAAACAAGACAACTTGAGCTGAAAGCGAAAAACTATGCTGACCAGAGAATGGAAGACATCGTAAAAGGAGCTCAAGAACTTGAT
AACGTAATCAAGCAAGGATACTTGGAGAAGAAAAGCAAAGATCATAGTTTCTTTGGATCGGAGTGGCAGAAGCGATGGTGTGTTGTCAGC
AGAGGTCTCTTCTACTACTATGCTAATGAGAAGAGCAAGCAGCCCAAAGGGACCTTCCTCATTAAGGGCTACGGTGTACGGATGGCCCCC
CACCTGCGAAGAGATTCCAAGAAAGAATCCTGCTTTGAACTGACCTCCCAGGATAGGCGCAGCTATGAGTTTACAGCTACTAGTCCAGCA
GAAGCCAGAGACTGGGTGGATCAAATAAGTTTCTTGTTAAAGGATCTGAGCTCCTTAACCATTCCATATGAAGAGGATGAGGAGGAAGAA
GAAAAAGAAGAGACATATGATGATATTGATGGTTTTGACTCCCCAAGTTGTGGTTCCCAGTGCAGACCCACTATCTTGCCTGGGAGTGTG
GGGATAAAAGAGCCTACAGAGGAGAAAGAAGAAGAAGATATTTATGAAGTCTTGCCAGATGAAGAGCATGATCTAGAAGAGGATGAGAGT
GGCACTCGACGAAAAGGAGTAGACTATGCCAGTTACTACCAGGGCCTATGGGATTGCCATGGTGACCAGCCAGATGAACTGTCCTTCCAA
CGGGGTGACCTCATCCGTATTCTGAGCAAGGAGTATAACATGTATGGCTGGTGGGTGGGAGAACTGAACAGCCTCGTTGGGATTGTTCCA
AAGGAGTATCTCACCACTGCCTTTGAAGTGGAAGAAAGATGAAACCCAGGAAATATATTCTTCCCTCTCTCCTGCCTTTATGAGGAAACT
GATCATCAAAAGTTCCCACTCCCTACTTCTGCCACCCCACCAACGCCTTGGACTCCTCTCTTTGCTGAAGAGACCCAAGTCTCTTGACAC
CTCAGAGTGACTGTAAGCTACCAGTAAGACAAGTGGGAAGAGGCACGTTCATCAAACCTGTTACTAAACCAGCCTAGTCATAGCTCATCC
CCATCTCTAAATGTGTCCACACAACCACATCTGCCTTTTCCACAAGCTTTTCACAAAGAAGGTGAGAGAGAAGGAAACCTTGGGAGGAGG

>85465_85465_8_SPAG9-SKAP1_SPAG9_chr17_49156944_ENST00000505279_SKAP1_chr17_46266862_ENST00000336915_length(amino acids)=407AA_BP=142
MELEDGVVYQEEPGGSGAVMSERVSGLAGSIYREFERLIGRYDEEVVKELMPLVVAVLENLDSVFAQDQEHQVELELLRDDNEQLITQYE
REKALRKHAEEKFIEFEDSQEQEKKDLQTRVESLESQTRQLELKAKNYADQRMEDIVKGAQELDNVIKQGYLEKKSKDHSFFGSEWQKRW
CVVSRGLFYYYANEKSKQPKGTFLIKGYGVRMAPHLRRDSKKESCFELTSQDRRSYEFTATSPAEARDWVDQISFLLKDLSSLTIPYEED
EEEEEKEETYDDIDGFDSPSCGSQCRPTILPGSVGIKEPTEEKEEEDIYEVLPDEEHDLEEDESGTRRKGVDYASYYQGLWDCHGDQPDE

--------------------------------------------------------------
>85465_85465_9_SPAG9-SKAP1_SPAG9_chr17_49156944_ENST00000505279_SKAP1_chr17_46266862_ENST00000584924_length(transcript)=1600nt_BP=502nt
GTCGGGTCCGTCCCGTGCGGGCAGGTGCCGCCCCTCTGCCGGCGACGCCCCGGGCCGCCCGCCCGTCCGCTTGCCACCATGGAGCTGGAG
GACGGTGTGGTGTATCAGGAGGAGCCCGGCGGCTCCGGGGCCGTGATGTCGGAGCGGGTGTCCGGCCTGGCCGGCTCCATCTACCGCGAG
TTCGAGCGGCTTATCGGGCGCTATGACGAGGAGGTGGTCAAAGAGCTGATGCCGCTGGTGGTGGCTGTGCTGGAGAACCTGGACTCGGTG
TTCGCGCAGGACCAGGAGCACCAGGTGGAGCTGGAGCTGCTGCGGGACGACAACGAGCAGCTCATCACCCAGTACGAGCGGGAGAAGGCG
CTGCGCAAGCACGCTGAGGAGAAATTCATTGAATTTGAAGACTCTCAAGAACAGGAAAAAAAGGACTTACAGACCCGAGTGGAATCTTTA
GAATCTCAAACAAGACAACTTGAGCTGAAAGCGAAAAACTATGCTGACCAGAGAATGGAAGACATCGTAAAAGGAGCTCAAGAACTTGAT
AACGTAATCAAGCAAGGATACTTGGAGAAGAAAAGCAAAGATCATAGTTTCTTTGGATCGGAGTGGCAGAAGCGATGGTGTGTTGTCAGC
AGAGGTCTCTTCTACTACTATGCTAATGAGAAGAGCAAGCAGCCCAAAGGGACCTTCCTCATTAAGGGCTACGGTGTACGGATGGCCCCC
CACCTGCGAAGAGATTCCAAGAAAGAATCCTGCTTTGAACTGACCTCCCAGGATAGGCGCAGCTATGAGTTTACAGCTACTAGTCCAGCA
GAAGCCAGAGACTGGGTGGATCAAATAAGTTTCTTGTTAAAGGATCTGAGCTCCTTAACCATTCCATATGAAGAGGATGAGGAGGAAGAA
GAAAAAGAAGAGACATATGATGATATTGATGGTTTTGACTCCCCAAGTTGTGGTTCCCAGTGCAGACCCACTATCTTGCCTGGGAGTGTG
GGGATAAAAGAGCCTACAGAGGAGAAAGAAGAAGAAGATATTTATGAAGTCTTGCCAGATGAAGAGCATGATCTAGAAGAGGATGAGAGT
GGCACTCGACGAAAAGGAGTAGACTATGCCAGTTACTACCAGGGCCTATGGGATTGCCATGGTGACCAGCCAGATGAACTGTCCTTCCAA
CGGGGTGACCTCATCCGTATTCTGAGCAAGGAGTATAACATGTATGGCTGGTGGGTGGGAGAACTGAACAGCCTCGTTGGGATTGTTCCA
AAGGAGTATCTCACCACTGCCTTTGAAGTGGAAGAAAGATGAAACCCAGGTATCAGAACCATGGCCAATGAACTGCCTAATAGTTGAGTG
GAACTTGTGGGCCACTACTTTGTTTCTCTGAAAGATGAGAGTTGCCAGTGAAGTAGCTTTTCTTCATTTCTCATACTAATGCTAGTGATT
CACCACTGATGGAAAGAAAATGCCTCTGGAATTGTTTTTTTCTTAAATTTGGGGACAGTGTCACTTAGGATAAGGTTCAACTAATAGCAA

>85465_85465_9_SPAG9-SKAP1_SPAG9_chr17_49156944_ENST00000505279_SKAP1_chr17_46266862_ENST00000584924_length(amino acids)=407AA_BP=142
MELEDGVVYQEEPGGSGAVMSERVSGLAGSIYREFERLIGRYDEEVVKELMPLVVAVLENLDSVFAQDQEHQVELELLRDDNEQLITQYE
REKALRKHAEEKFIEFEDSQEQEKKDLQTRVESLESQTRQLELKAKNYADQRMEDIVKGAQELDNVIKQGYLEKKSKDHSFFGSEWQKRW
CVVSRGLFYYYANEKSKQPKGTFLIKGYGVRMAPHLRRDSKKESCFELTSQDRRSYEFTATSPAEARDWVDQISFLLKDLSSLTIPYEED
EEEEEKEETYDDIDGFDSPSCGSQCRPTILPGSVGIKEPTEEKEEEDIYEVLPDEEHDLEEDESGTRRKGVDYASYYQGLWDCHGDQPDE

--------------------------------------------------------------
>85465_85465_10_SPAG9-SKAP1_SPAG9_chr17_49156945_ENST00000262013_SKAP1_chr17_46266862_ENST00000336915_length(transcript)=1817nt_BP=633nt
AGTTGGTGCAGCGGCGGTTGGGGTGAGAGCGCCTACGCCACCCCTCCCCTCCTCCGGCCCCGGCCCCCACCCCGCCGGGCCCAGCCCCAG
CCCCGGCCCGGGCTCCAGCCCTAGTACCCGTCCCAGCCCGAGTCGGGTCCGTCCCGTGCGGGCAGGTGCCGCCCCTCTGCCGGCGACGCC
CCGGGCCGCCCGCCCGTCCGCTTGCCACCATGGAGCTGGAGGACGGTGTGGTGTATCAGGAGGAGCCCGGCGGCTCCGGGGCCGTGATGT
CGGAGCGGGTGTCCGGCCTGGCCGGCTCCATCTACCGCGAGTTCGAGCGGCTTATCGGGCGCTATGACGAGGAGGTGGTCAAAGAGCTGA
TGCCGCTGGTGGTGGCTGTGCTGGAGAACCTGGACTCGGTGTTCGCGCAGGACCAGGAGCACCAGGTGGAGCTGGAGCTGCTGCGGGACG
ACAACGAGCAGCTCATCACCCAGTACGAGCGGGAGAAGGCGCTGCGCAAGCACGCTGAGGAGAAATTCATTGAATTTGAAGACTCTCAAG
AACAGGAAAAAAAGGACTTACAGACCCGAGTGGAATCTTTAGAATCTCAAACAAGACAACTTGAGCTGAAAGCGAAAAACTATGCTGACC
AGAGAATGGAAGACATCGTAAAAGGAGCTCAAGAACTTGATAACGTAATCAAGCAAGGATACTTGGAGAAGAAAAGCAAAGATCATAGTT
TCTTTGGATCGGAGTGGCAGAAGCGATGGTGTGTTGTCAGCAGAGGTCTCTTCTACTACTATGCTAATGAGAAGAGCAAGCAGCCCAAAG
GGACCTTCCTCATTAAGGGCTACGGTGTACGGATGGCCCCCCACCTGCGAAGAGATTCCAAGAAAGAATCCTGCTTTGAACTGACCTCCC
AGGATAGGCGCAGCTATGAGTTTACAGCTACTAGTCCAGCAGAAGCCAGAGACTGGGTGGATCAAATAAGTTTCTTGTTAAAGGATCTGA
GCTCCTTAACCATTCCATATGAAGAGGATGAGGAGGAAGAAGAAAAAGAAGAGACATATGATGATATTGATGGTTTTGACTCCCCAAGTT
GTGGTTCCCAGTGCAGACCCACTATCTTGCCTGGGAGTGTGGGGATAAAAGAGCCTACAGAGGAGAAAGAAGAAGAAGATATTTATGAAG
TCTTGCCAGATGAAGAGCATGATCTAGAAGAGGATGAGAGTGGCACTCGACGAAAAGGAGTAGACTATGCCAGTTACTACCAGGGCCTAT
GGGATTGCCATGGTGACCAGCCAGATGAACTGTCCTTCCAACGGGGTGACCTCATCCGTATTCTGAGCAAGGAGTATAACATGTATGGCT
GGTGGGTGGGAGAACTGAACAGCCTCGTTGGGATTGTTCCAAAGGAGTATCTCACCACTGCCTTTGAAGTGGAAGAAAGATGAAACCCAG
GAAATATATTCTTCCCTCTCTCCTGCCTTTATGAGGAAACTGATCATCAAAAGTTCCCACTCCCTACTTCTGCCACCCCACCAACGCCTT
GGACTCCTCTCTTTGCTGAAGAGACCCAAGTCTCTTGACACCTCAGAGTGACTGTAAGCTACCAGTAAGACAAGTGGGAAGAGGCACGTT
CATCAAACCTGTTACTAAACCAGCCTAGTCATAGCTCATCCCCATCTCTAAATGTGTCCACACAACCACATCTGCCTTTTCCACAAGCTT
TTCACAAAGAAGGTGAGAGAGAAGGAAACCTTGGGAGGAGGACATTACTGGTTGTTCTGGCTGGTTTGAAAAGCACAAATAAACTTGGGA

>85465_85465_10_SPAG9-SKAP1_SPAG9_chr17_49156945_ENST00000262013_SKAP1_chr17_46266862_ENST00000336915_length(amino acids)=407AA_BP=142
MELEDGVVYQEEPGGSGAVMSERVSGLAGSIYREFERLIGRYDEEVVKELMPLVVAVLENLDSVFAQDQEHQVELELLRDDNEQLITQYE
REKALRKHAEEKFIEFEDSQEQEKKDLQTRVESLESQTRQLELKAKNYADQRMEDIVKGAQELDNVIKQGYLEKKSKDHSFFGSEWQKRW
CVVSRGLFYYYANEKSKQPKGTFLIKGYGVRMAPHLRRDSKKESCFELTSQDRRSYEFTATSPAEARDWVDQISFLLKDLSSLTIPYEED
EEEEEKEETYDDIDGFDSPSCGSQCRPTILPGSVGIKEPTEEKEEEDIYEVLPDEEHDLEEDESGTRRKGVDYASYYQGLWDCHGDQPDE

--------------------------------------------------------------
>85465_85465_11_SPAG9-SKAP1_SPAG9_chr17_49156945_ENST00000262013_SKAP1_chr17_46266862_ENST00000584924_length(transcript)=1731nt_BP=633nt
AGTTGGTGCAGCGGCGGTTGGGGTGAGAGCGCCTACGCCACCCCTCCCCTCCTCCGGCCCCGGCCCCCACCCCGCCGGGCCCAGCCCCAG
CCCCGGCCCGGGCTCCAGCCCTAGTACCCGTCCCAGCCCGAGTCGGGTCCGTCCCGTGCGGGCAGGTGCCGCCCCTCTGCCGGCGACGCC
CCGGGCCGCCCGCCCGTCCGCTTGCCACCATGGAGCTGGAGGACGGTGTGGTGTATCAGGAGGAGCCCGGCGGCTCCGGGGCCGTGATGT
CGGAGCGGGTGTCCGGCCTGGCCGGCTCCATCTACCGCGAGTTCGAGCGGCTTATCGGGCGCTATGACGAGGAGGTGGTCAAAGAGCTGA
TGCCGCTGGTGGTGGCTGTGCTGGAGAACCTGGACTCGGTGTTCGCGCAGGACCAGGAGCACCAGGTGGAGCTGGAGCTGCTGCGGGACG
ACAACGAGCAGCTCATCACCCAGTACGAGCGGGAGAAGGCGCTGCGCAAGCACGCTGAGGAGAAATTCATTGAATTTGAAGACTCTCAAG
AACAGGAAAAAAAGGACTTACAGACCCGAGTGGAATCTTTAGAATCTCAAACAAGACAACTTGAGCTGAAAGCGAAAAACTATGCTGACC
AGAGAATGGAAGACATCGTAAAAGGAGCTCAAGAACTTGATAACGTAATCAAGCAAGGATACTTGGAGAAGAAAAGCAAAGATCATAGTT
TCTTTGGATCGGAGTGGCAGAAGCGATGGTGTGTTGTCAGCAGAGGTCTCTTCTACTACTATGCTAATGAGAAGAGCAAGCAGCCCAAAG
GGACCTTCCTCATTAAGGGCTACGGTGTACGGATGGCCCCCCACCTGCGAAGAGATTCCAAGAAAGAATCCTGCTTTGAACTGACCTCCC
AGGATAGGCGCAGCTATGAGTTTACAGCTACTAGTCCAGCAGAAGCCAGAGACTGGGTGGATCAAATAAGTTTCTTGTTAAAGGATCTGA
GCTCCTTAACCATTCCATATGAAGAGGATGAGGAGGAAGAAGAAAAAGAAGAGACATATGATGATATTGATGGTTTTGACTCCCCAAGTT
GTGGTTCCCAGTGCAGACCCACTATCTTGCCTGGGAGTGTGGGGATAAAAGAGCCTACAGAGGAGAAAGAAGAAGAAGATATTTATGAAG
TCTTGCCAGATGAAGAGCATGATCTAGAAGAGGATGAGAGTGGCACTCGACGAAAAGGAGTAGACTATGCCAGTTACTACCAGGGCCTAT
GGGATTGCCATGGTGACCAGCCAGATGAACTGTCCTTCCAACGGGGTGACCTCATCCGTATTCTGAGCAAGGAGTATAACATGTATGGCT
GGTGGGTGGGAGAACTGAACAGCCTCGTTGGGATTGTTCCAAAGGAGTATCTCACCACTGCCTTTGAAGTGGAAGAAAGATGAAACCCAG
GTATCAGAACCATGGCCAATGAACTGCCTAATAGTTGAGTGGAACTTGTGGGCCACTACTTTGTTTCTCTGAAAGATGAGAGTTGCCAGT
GAAGTAGCTTTTCTTCATTTCTCATACTAATGCTAGTGATTCACCACTGATGGAAAGAAAATGCCTCTGGAATTGTTTTTTTCTTAAATT
TGGGGACAGTGTCACTTAGGATAAGGTTCAACTAATAGCAACATAAAATCTAAACTAAAAATGACTTAATTAACACAGAAAGCCAGGCAC

>85465_85465_11_SPAG9-SKAP1_SPAG9_chr17_49156945_ENST00000262013_SKAP1_chr17_46266862_ENST00000584924_length(amino acids)=407AA_BP=142
MELEDGVVYQEEPGGSGAVMSERVSGLAGSIYREFERLIGRYDEEVVKELMPLVVAVLENLDSVFAQDQEHQVELELLRDDNEQLITQYE
REKALRKHAEEKFIEFEDSQEQEKKDLQTRVESLESQTRQLELKAKNYADQRMEDIVKGAQELDNVIKQGYLEKKSKDHSFFGSEWQKRW
CVVSRGLFYYYANEKSKQPKGTFLIKGYGVRMAPHLRRDSKKESCFELTSQDRRSYEFTATSPAEARDWVDQISFLLKDLSSLTIPYEED
EEEEEKEETYDDIDGFDSPSCGSQCRPTILPGSVGIKEPTEEKEEEDIYEVLPDEEHDLEEDESGTRRKGVDYASYYQGLWDCHGDQPDE

--------------------------------------------------------------
>85465_85465_12_SPAG9-SKAP1_SPAG9_chr17_49156945_ENST00000357122_SKAP1_chr17_46266862_ENST00000336915_length(transcript)=1817nt_BP=633nt
AGTTGGTGCAGCGGCGGTTGGGGTGAGAGCGCCTACGCCACCCCTCCCCTCCTCCGGCCCCGGCCCCCACCCCGCCGGGCCCAGCCCCAG
CCCCGGCCCGGGCTCCAGCCCTAGTACCCGTCCCAGCCCGAGTCGGGTCCGTCCCGTGCGGGCAGGTGCCGCCCCTCTGCCGGCGACGCC
CCGGGCCGCCCGCCCGTCCGCTTGCCACCATGGAGCTGGAGGACGGTGTGGTGTATCAGGAGGAGCCCGGCGGCTCCGGGGCCGTGATGT
CGGAGCGGGTGTCCGGCCTGGCCGGCTCCATCTACCGCGAGTTCGAGCGGCTTATCGGGCGCTATGACGAGGAGGTGGTCAAAGAGCTGA
TGCCGCTGGTGGTGGCTGTGCTGGAGAACCTGGACTCGGTGTTCGCGCAGGACCAGGAGCACCAGGTGGAGCTGGAGCTGCTGCGGGACG
ACAACGAGCAGCTCATCACCCAGTACGAGCGGGAGAAGGCGCTGCGCAAGCACGCTGAGGAGAAATTCATTGAATTTGAAGACTCTCAAG
AACAGGAAAAAAAGGACTTACAGACCCGAGTGGAATCTTTAGAATCTCAAACAAGACAACTTGAGCTGAAAGCGAAAAACTATGCTGACC
AGAGAATGGAAGACATCGTAAAAGGAGCTCAAGAACTTGATAACGTAATCAAGCAAGGATACTTGGAGAAGAAAAGCAAAGATCATAGTT
TCTTTGGATCGGAGTGGCAGAAGCGATGGTGTGTTGTCAGCAGAGGTCTCTTCTACTACTATGCTAATGAGAAGAGCAAGCAGCCCAAAG
GGACCTTCCTCATTAAGGGCTACGGTGTACGGATGGCCCCCCACCTGCGAAGAGATTCCAAGAAAGAATCCTGCTTTGAACTGACCTCCC
AGGATAGGCGCAGCTATGAGTTTACAGCTACTAGTCCAGCAGAAGCCAGAGACTGGGTGGATCAAATAAGTTTCTTGTTAAAGGATCTGA
GCTCCTTAACCATTCCATATGAAGAGGATGAGGAGGAAGAAGAAAAAGAAGAGACATATGATGATATTGATGGTTTTGACTCCCCAAGTT
GTGGTTCCCAGTGCAGACCCACTATCTTGCCTGGGAGTGTGGGGATAAAAGAGCCTACAGAGGAGAAAGAAGAAGAAGATATTTATGAAG
TCTTGCCAGATGAAGAGCATGATCTAGAAGAGGATGAGAGTGGCACTCGACGAAAAGGAGTAGACTATGCCAGTTACTACCAGGGCCTAT
GGGATTGCCATGGTGACCAGCCAGATGAACTGTCCTTCCAACGGGGTGACCTCATCCGTATTCTGAGCAAGGAGTATAACATGTATGGCT
GGTGGGTGGGAGAACTGAACAGCCTCGTTGGGATTGTTCCAAAGGAGTATCTCACCACTGCCTTTGAAGTGGAAGAAAGATGAAACCCAG
GAAATATATTCTTCCCTCTCTCCTGCCTTTATGAGGAAACTGATCATCAAAAGTTCCCACTCCCTACTTCTGCCACCCCACCAACGCCTT
GGACTCCTCTCTTTGCTGAAGAGACCCAAGTCTCTTGACACCTCAGAGTGACTGTAAGCTACCAGTAAGACAAGTGGGAAGAGGCACGTT
CATCAAACCTGTTACTAAACCAGCCTAGTCATAGCTCATCCCCATCTCTAAATGTGTCCACACAACCACATCTGCCTTTTCCACAAGCTT
TTCACAAAGAAGGTGAGAGAGAAGGAAACCTTGGGAGGAGGACATTACTGGTTGTTCTGGCTGGTTTGAAAAGCACAAATAAACTTGGGA

>85465_85465_12_SPAG9-SKAP1_SPAG9_chr17_49156945_ENST00000357122_SKAP1_chr17_46266862_ENST00000336915_length(amino acids)=407AA_BP=142
MELEDGVVYQEEPGGSGAVMSERVSGLAGSIYREFERLIGRYDEEVVKELMPLVVAVLENLDSVFAQDQEHQVELELLRDDNEQLITQYE
REKALRKHAEEKFIEFEDSQEQEKKDLQTRVESLESQTRQLELKAKNYADQRMEDIVKGAQELDNVIKQGYLEKKSKDHSFFGSEWQKRW
CVVSRGLFYYYANEKSKQPKGTFLIKGYGVRMAPHLRRDSKKESCFELTSQDRRSYEFTATSPAEARDWVDQISFLLKDLSSLTIPYEED
EEEEEKEETYDDIDGFDSPSCGSQCRPTILPGSVGIKEPTEEKEEEDIYEVLPDEEHDLEEDESGTRRKGVDYASYYQGLWDCHGDQPDE

--------------------------------------------------------------
>85465_85465_13_SPAG9-SKAP1_SPAG9_chr17_49156945_ENST00000357122_SKAP1_chr17_46266862_ENST00000584924_length(transcript)=1731nt_BP=633nt
AGTTGGTGCAGCGGCGGTTGGGGTGAGAGCGCCTACGCCACCCCTCCCCTCCTCCGGCCCCGGCCCCCACCCCGCCGGGCCCAGCCCCAG
CCCCGGCCCGGGCTCCAGCCCTAGTACCCGTCCCAGCCCGAGTCGGGTCCGTCCCGTGCGGGCAGGTGCCGCCCCTCTGCCGGCGACGCC
CCGGGCCGCCCGCCCGTCCGCTTGCCACCATGGAGCTGGAGGACGGTGTGGTGTATCAGGAGGAGCCCGGCGGCTCCGGGGCCGTGATGT
CGGAGCGGGTGTCCGGCCTGGCCGGCTCCATCTACCGCGAGTTCGAGCGGCTTATCGGGCGCTATGACGAGGAGGTGGTCAAAGAGCTGA
TGCCGCTGGTGGTGGCTGTGCTGGAGAACCTGGACTCGGTGTTCGCGCAGGACCAGGAGCACCAGGTGGAGCTGGAGCTGCTGCGGGACG
ACAACGAGCAGCTCATCACCCAGTACGAGCGGGAGAAGGCGCTGCGCAAGCACGCTGAGGAGAAATTCATTGAATTTGAAGACTCTCAAG
AACAGGAAAAAAAGGACTTACAGACCCGAGTGGAATCTTTAGAATCTCAAACAAGACAACTTGAGCTGAAAGCGAAAAACTATGCTGACC
AGAGAATGGAAGACATCGTAAAAGGAGCTCAAGAACTTGATAACGTAATCAAGCAAGGATACTTGGAGAAGAAAAGCAAAGATCATAGTT
TCTTTGGATCGGAGTGGCAGAAGCGATGGTGTGTTGTCAGCAGAGGTCTCTTCTACTACTATGCTAATGAGAAGAGCAAGCAGCCCAAAG
GGACCTTCCTCATTAAGGGCTACGGTGTACGGATGGCCCCCCACCTGCGAAGAGATTCCAAGAAAGAATCCTGCTTTGAACTGACCTCCC
AGGATAGGCGCAGCTATGAGTTTACAGCTACTAGTCCAGCAGAAGCCAGAGACTGGGTGGATCAAATAAGTTTCTTGTTAAAGGATCTGA
GCTCCTTAACCATTCCATATGAAGAGGATGAGGAGGAAGAAGAAAAAGAAGAGACATATGATGATATTGATGGTTTTGACTCCCCAAGTT
GTGGTTCCCAGTGCAGACCCACTATCTTGCCTGGGAGTGTGGGGATAAAAGAGCCTACAGAGGAGAAAGAAGAAGAAGATATTTATGAAG
TCTTGCCAGATGAAGAGCATGATCTAGAAGAGGATGAGAGTGGCACTCGACGAAAAGGAGTAGACTATGCCAGTTACTACCAGGGCCTAT
GGGATTGCCATGGTGACCAGCCAGATGAACTGTCCTTCCAACGGGGTGACCTCATCCGTATTCTGAGCAAGGAGTATAACATGTATGGCT
GGTGGGTGGGAGAACTGAACAGCCTCGTTGGGATTGTTCCAAAGGAGTATCTCACCACTGCCTTTGAAGTGGAAGAAAGATGAAACCCAG
GTATCAGAACCATGGCCAATGAACTGCCTAATAGTTGAGTGGAACTTGTGGGCCACTACTTTGTTTCTCTGAAAGATGAGAGTTGCCAGT
GAAGTAGCTTTTCTTCATTTCTCATACTAATGCTAGTGATTCACCACTGATGGAAAGAAAATGCCTCTGGAATTGTTTTTTTCTTAAATT
TGGGGACAGTGTCACTTAGGATAAGGTTCAACTAATAGCAACATAAAATCTAAACTAAAAATGACTTAATTAACACAGAAAGCCAGGCAC

>85465_85465_13_SPAG9-SKAP1_SPAG9_chr17_49156945_ENST00000357122_SKAP1_chr17_46266862_ENST00000584924_length(amino acids)=407AA_BP=142
MELEDGVVYQEEPGGSGAVMSERVSGLAGSIYREFERLIGRYDEEVVKELMPLVVAVLENLDSVFAQDQEHQVELELLRDDNEQLITQYE
REKALRKHAEEKFIEFEDSQEQEKKDLQTRVESLESQTRQLELKAKNYADQRMEDIVKGAQELDNVIKQGYLEKKSKDHSFFGSEWQKRW
CVVSRGLFYYYANEKSKQPKGTFLIKGYGVRMAPHLRRDSKKESCFELTSQDRRSYEFTATSPAEARDWVDQISFLLKDLSSLTIPYEED
EEEEEKEETYDDIDGFDSPSCGSQCRPTILPGSVGIKEPTEEKEEEDIYEVLPDEEHDLEEDESGTRRKGVDYASYYQGLWDCHGDQPDE

--------------------------------------------------------------
>85465_85465_14_SPAG9-SKAP1_SPAG9_chr17_49156945_ENST00000505279_SKAP1_chr17_46266862_ENST00000336915_length(transcript)=1686nt_BP=502nt
GTCGGGTCCGTCCCGTGCGGGCAGGTGCCGCCCCTCTGCCGGCGACGCCCCGGGCCGCCCGCCCGTCCGCTTGCCACCATGGAGCTGGAG
GACGGTGTGGTGTATCAGGAGGAGCCCGGCGGCTCCGGGGCCGTGATGTCGGAGCGGGTGTCCGGCCTGGCCGGCTCCATCTACCGCGAG
TTCGAGCGGCTTATCGGGCGCTATGACGAGGAGGTGGTCAAAGAGCTGATGCCGCTGGTGGTGGCTGTGCTGGAGAACCTGGACTCGGTG
TTCGCGCAGGACCAGGAGCACCAGGTGGAGCTGGAGCTGCTGCGGGACGACAACGAGCAGCTCATCACCCAGTACGAGCGGGAGAAGGCG
CTGCGCAAGCACGCTGAGGAGAAATTCATTGAATTTGAAGACTCTCAAGAACAGGAAAAAAAGGACTTACAGACCCGAGTGGAATCTTTA
GAATCTCAAACAAGACAACTTGAGCTGAAAGCGAAAAACTATGCTGACCAGAGAATGGAAGACATCGTAAAAGGAGCTCAAGAACTTGAT
AACGTAATCAAGCAAGGATACTTGGAGAAGAAAAGCAAAGATCATAGTTTCTTTGGATCGGAGTGGCAGAAGCGATGGTGTGTTGTCAGC
AGAGGTCTCTTCTACTACTATGCTAATGAGAAGAGCAAGCAGCCCAAAGGGACCTTCCTCATTAAGGGCTACGGTGTACGGATGGCCCCC
CACCTGCGAAGAGATTCCAAGAAAGAATCCTGCTTTGAACTGACCTCCCAGGATAGGCGCAGCTATGAGTTTACAGCTACTAGTCCAGCA
GAAGCCAGAGACTGGGTGGATCAAATAAGTTTCTTGTTAAAGGATCTGAGCTCCTTAACCATTCCATATGAAGAGGATGAGGAGGAAGAA
GAAAAAGAAGAGACATATGATGATATTGATGGTTTTGACTCCCCAAGTTGTGGTTCCCAGTGCAGACCCACTATCTTGCCTGGGAGTGTG
GGGATAAAAGAGCCTACAGAGGAGAAAGAAGAAGAAGATATTTATGAAGTCTTGCCAGATGAAGAGCATGATCTAGAAGAGGATGAGAGT
GGCACTCGACGAAAAGGAGTAGACTATGCCAGTTACTACCAGGGCCTATGGGATTGCCATGGTGACCAGCCAGATGAACTGTCCTTCCAA
CGGGGTGACCTCATCCGTATTCTGAGCAAGGAGTATAACATGTATGGCTGGTGGGTGGGAGAACTGAACAGCCTCGTTGGGATTGTTCCA
AAGGAGTATCTCACCACTGCCTTTGAAGTGGAAGAAAGATGAAACCCAGGAAATATATTCTTCCCTCTCTCCTGCCTTTATGAGGAAACT
GATCATCAAAAGTTCCCACTCCCTACTTCTGCCACCCCACCAACGCCTTGGACTCCTCTCTTTGCTGAAGAGACCCAAGTCTCTTGACAC
CTCAGAGTGACTGTAAGCTACCAGTAAGACAAGTGGGAAGAGGCACGTTCATCAAACCTGTTACTAAACCAGCCTAGTCATAGCTCATCC
CCATCTCTAAATGTGTCCACACAACCACATCTGCCTTTTCCACAAGCTTTTCACAAAGAAGGTGAGAGAGAAGGAAACCTTGGGAGGAGG

>85465_85465_14_SPAG9-SKAP1_SPAG9_chr17_49156945_ENST00000505279_SKAP1_chr17_46266862_ENST00000336915_length(amino acids)=407AA_BP=142
MELEDGVVYQEEPGGSGAVMSERVSGLAGSIYREFERLIGRYDEEVVKELMPLVVAVLENLDSVFAQDQEHQVELELLRDDNEQLITQYE
REKALRKHAEEKFIEFEDSQEQEKKDLQTRVESLESQTRQLELKAKNYADQRMEDIVKGAQELDNVIKQGYLEKKSKDHSFFGSEWQKRW
CVVSRGLFYYYANEKSKQPKGTFLIKGYGVRMAPHLRRDSKKESCFELTSQDRRSYEFTATSPAEARDWVDQISFLLKDLSSLTIPYEED
EEEEEKEETYDDIDGFDSPSCGSQCRPTILPGSVGIKEPTEEKEEEDIYEVLPDEEHDLEEDESGTRRKGVDYASYYQGLWDCHGDQPDE

--------------------------------------------------------------
>85465_85465_15_SPAG9-SKAP1_SPAG9_chr17_49156945_ENST00000505279_SKAP1_chr17_46266862_ENST00000584924_length(transcript)=1600nt_BP=502nt
GTCGGGTCCGTCCCGTGCGGGCAGGTGCCGCCCCTCTGCCGGCGACGCCCCGGGCCGCCCGCCCGTCCGCTTGCCACCATGGAGCTGGAG
GACGGTGTGGTGTATCAGGAGGAGCCCGGCGGCTCCGGGGCCGTGATGTCGGAGCGGGTGTCCGGCCTGGCCGGCTCCATCTACCGCGAG
TTCGAGCGGCTTATCGGGCGCTATGACGAGGAGGTGGTCAAAGAGCTGATGCCGCTGGTGGTGGCTGTGCTGGAGAACCTGGACTCGGTG
TTCGCGCAGGACCAGGAGCACCAGGTGGAGCTGGAGCTGCTGCGGGACGACAACGAGCAGCTCATCACCCAGTACGAGCGGGAGAAGGCG
CTGCGCAAGCACGCTGAGGAGAAATTCATTGAATTTGAAGACTCTCAAGAACAGGAAAAAAAGGACTTACAGACCCGAGTGGAATCTTTA
GAATCTCAAACAAGACAACTTGAGCTGAAAGCGAAAAACTATGCTGACCAGAGAATGGAAGACATCGTAAAAGGAGCTCAAGAACTTGAT
AACGTAATCAAGCAAGGATACTTGGAGAAGAAAAGCAAAGATCATAGTTTCTTTGGATCGGAGTGGCAGAAGCGATGGTGTGTTGTCAGC
AGAGGTCTCTTCTACTACTATGCTAATGAGAAGAGCAAGCAGCCCAAAGGGACCTTCCTCATTAAGGGCTACGGTGTACGGATGGCCCCC
CACCTGCGAAGAGATTCCAAGAAAGAATCCTGCTTTGAACTGACCTCCCAGGATAGGCGCAGCTATGAGTTTACAGCTACTAGTCCAGCA
GAAGCCAGAGACTGGGTGGATCAAATAAGTTTCTTGTTAAAGGATCTGAGCTCCTTAACCATTCCATATGAAGAGGATGAGGAGGAAGAA
GAAAAAGAAGAGACATATGATGATATTGATGGTTTTGACTCCCCAAGTTGTGGTTCCCAGTGCAGACCCACTATCTTGCCTGGGAGTGTG
GGGATAAAAGAGCCTACAGAGGAGAAAGAAGAAGAAGATATTTATGAAGTCTTGCCAGATGAAGAGCATGATCTAGAAGAGGATGAGAGT
GGCACTCGACGAAAAGGAGTAGACTATGCCAGTTACTACCAGGGCCTATGGGATTGCCATGGTGACCAGCCAGATGAACTGTCCTTCCAA
CGGGGTGACCTCATCCGTATTCTGAGCAAGGAGTATAACATGTATGGCTGGTGGGTGGGAGAACTGAACAGCCTCGTTGGGATTGTTCCA
AAGGAGTATCTCACCACTGCCTTTGAAGTGGAAGAAAGATGAAACCCAGGTATCAGAACCATGGCCAATGAACTGCCTAATAGTTGAGTG
GAACTTGTGGGCCACTACTTTGTTTCTCTGAAAGATGAGAGTTGCCAGTGAAGTAGCTTTTCTTCATTTCTCATACTAATGCTAGTGATT
CACCACTGATGGAAAGAAAATGCCTCTGGAATTGTTTTTTTCTTAAATTTGGGGACAGTGTCACTTAGGATAAGGTTCAACTAATAGCAA

>85465_85465_15_SPAG9-SKAP1_SPAG9_chr17_49156945_ENST00000505279_SKAP1_chr17_46266862_ENST00000584924_length(amino acids)=407AA_BP=142
MELEDGVVYQEEPGGSGAVMSERVSGLAGSIYREFERLIGRYDEEVVKELMPLVVAVLENLDSVFAQDQEHQVELELLRDDNEQLITQYE
REKALRKHAEEKFIEFEDSQEQEKKDLQTRVESLESQTRQLELKAKNYADQRMEDIVKGAQELDNVIKQGYLEKKSKDHSFFGSEWQKRW
CVVSRGLFYYYANEKSKQPKGTFLIKGYGVRMAPHLRRDSKKESCFELTSQDRRSYEFTATSPAEARDWVDQISFLLKDLSSLTIPYEED
EEEEEKEETYDDIDGFDSPSCGSQCRPTILPGSVGIKEPTEEKEEEDIYEVLPDEEHDLEEDESGTRRKGVDYASYYQGLWDCHGDQPDE

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Fusion Gene PPI Analysis for SPAG9-SKAP1


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with
TgeneSKAP1chr17:49156944chr17:46266862ENST00000336915313290_29593.33333333333333448.0FYB1
TgeneSKAP1chr17:49156944chr17:46266862ENST00000584924312290_29593.33333333333333360.0FYB1
TgeneSKAP1chr17:49156945chr17:46266862ENST00000336915313290_29593.33333333333333448.0FYB1
TgeneSKAP1chr17:49156945chr17:46266862ENST00000584924312290_29593.33333333333333360.0FYB1


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with
TgeneSKAP1chr17:49124736chr17:46214699ENST000003369151013290_295326.0448.0FYB1
TgeneSKAP1chr17:49124736chr17:46214699ENST000005849241012290_295326.0360.0FYB1


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for SPAG9-SKAP1


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for SPAG9-SKAP1


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource