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 | Fusion Gene Summary |
| Fusion Gene ORF analysis |
| Fusion Genomic Features |
| Fusion Protein Features |
| Fusion Gene Sequence |
| Fusion Gene PPI analysis |
| Related Drugs |
| Related Diseases |
Fusion gene:SPG11-CCDC14 (FusionGDB2 ID:85734) |
Fusion Gene Summary for SPG11-CCDC14 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: SPG11-CCDC14 | Fusion gene ID: 85734 | Hgene | Tgene | Gene symbol | SPG11 | CCDC14 | Gene ID | 80208 | 64770 |
| Gene name | SPG11 vesicle trafficking associated, spatacsin | coiled-coil domain containing 14 | |
| Synonyms | ALS5|CMT2X|KIAA1840 | - | |
| Cytomap | 15q21.1 | 3q21.1 | |
| Type of gene | protein-coding | protein-coding | |
| Description | spatacsinSPG11, spatacsin vesicle trafficking associatedamyotrophic lateral sclerosis 5colorectal carcinoma-associated proteinspastic paraplegia 11 (autosomal recessive)spastic paraplegia 11 protein | coiled-coil domain-containing protein 14 | |
| Modification date | 20200329 | 20200313 | |
| UniProtAcc | . | Q6ZUS6 | |
| Ensembl transtripts involved in fusion gene | ENST00000261866, ENST00000427534, ENST00000535302, ENST00000558319, ENST00000559193, ENST00000558253, | ENST00000433542, ENST00000485727, ENST00000489746, ENST00000483247, ENST00000310351, ENST00000488653, | |
| Fusion gene scores | * DoF score | 11 X 11 X 7=847 | 12 X 8 X 7=672 |
| # samples | 12 | 13 | |
| ** MAII score | log2(12/847*10)=-2.81932756372368 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(13/672*10)=-2.36994960975031 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: SPG11 [Title/Abstract] AND CCDC14 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Most frequent breakpoint | SPG11(44925703)-CCDC14(123667979), # samples:1 | ||
| Anticipated loss of major functional domain due to fusion event. | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene breakpoints across SPG11 (5'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
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| Fusion gene breakpoints across CCDC14 (3'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
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| Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Source | Disease | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| ChimerDB4 | Non-Cancer | TCGA-HU-A4GC-11A | SPG11 | chr15 | 44925703 | - | CCDC14 | chr3 | 123667979 | - |
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Fusion Gene ORF analysis for SPG11-CCDC14 |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| 5CDS-5UTR | ENST00000261866 | ENST00000433542 | SPG11 | chr15 | 44925703 | - | CCDC14 | chr3 | 123667979 | - |
| 5CDS-5UTR | ENST00000261866 | ENST00000485727 | SPG11 | chr15 | 44925703 | - | CCDC14 | chr3 | 123667979 | - |
| 5CDS-5UTR | ENST00000261866 | ENST00000489746 | SPG11 | chr15 | 44925703 | - | CCDC14 | chr3 | 123667979 | - |
| 5CDS-5UTR | ENST00000427534 | ENST00000433542 | SPG11 | chr15 | 44925703 | - | CCDC14 | chr3 | 123667979 | - |
| 5CDS-5UTR | ENST00000427534 | ENST00000485727 | SPG11 | chr15 | 44925703 | - | CCDC14 | chr3 | 123667979 | - |
| 5CDS-5UTR | ENST00000427534 | ENST00000489746 | SPG11 | chr15 | 44925703 | - | CCDC14 | chr3 | 123667979 | - |
| 5CDS-5UTR | ENST00000535302 | ENST00000433542 | SPG11 | chr15 | 44925703 | - | CCDC14 | chr3 | 123667979 | - |
| 5CDS-5UTR | ENST00000535302 | ENST00000485727 | SPG11 | chr15 | 44925703 | - | CCDC14 | chr3 | 123667979 | - |
| 5CDS-5UTR | ENST00000535302 | ENST00000489746 | SPG11 | chr15 | 44925703 | - | CCDC14 | chr3 | 123667979 | - |
| 5CDS-5UTR | ENST00000558319 | ENST00000433542 | SPG11 | chr15 | 44925703 | - | CCDC14 | chr3 | 123667979 | - |
| 5CDS-5UTR | ENST00000558319 | ENST00000485727 | SPG11 | chr15 | 44925703 | - | CCDC14 | chr3 | 123667979 | - |
| 5CDS-5UTR | ENST00000558319 | ENST00000489746 | SPG11 | chr15 | 44925703 | - | CCDC14 | chr3 | 123667979 | - |
| 5CDS-5UTR | ENST00000559193 | ENST00000433542 | SPG11 | chr15 | 44925703 | - | CCDC14 | chr3 | 123667979 | - |
| 5CDS-5UTR | ENST00000559193 | ENST00000485727 | SPG11 | chr15 | 44925703 | - | CCDC14 | chr3 | 123667979 | - |
| 5CDS-5UTR | ENST00000559193 | ENST00000489746 | SPG11 | chr15 | 44925703 | - | CCDC14 | chr3 | 123667979 | - |
| 5CDS-intron | ENST00000261866 | ENST00000483247 | SPG11 | chr15 | 44925703 | - | CCDC14 | chr3 | 123667979 | - |
| 5CDS-intron | ENST00000427534 | ENST00000483247 | SPG11 | chr15 | 44925703 | - | CCDC14 | chr3 | 123667979 | - |
| 5CDS-intron | ENST00000535302 | ENST00000483247 | SPG11 | chr15 | 44925703 | - | CCDC14 | chr3 | 123667979 | - |
| 5CDS-intron | ENST00000558319 | ENST00000483247 | SPG11 | chr15 | 44925703 | - | CCDC14 | chr3 | 123667979 | - |
| 5CDS-intron | ENST00000559193 | ENST00000483247 | SPG11 | chr15 | 44925703 | - | CCDC14 | chr3 | 123667979 | - |
| In-frame | ENST00000261866 | ENST00000310351 | SPG11 | chr15 | 44925703 | - | CCDC14 | chr3 | 123667979 | - |
| In-frame | ENST00000261866 | ENST00000488653 | SPG11 | chr15 | 44925703 | - | CCDC14 | chr3 | 123667979 | - |
| In-frame | ENST00000427534 | ENST00000310351 | SPG11 | chr15 | 44925703 | - | CCDC14 | chr3 | 123667979 | - |
| In-frame | ENST00000427534 | ENST00000488653 | SPG11 | chr15 | 44925703 | - | CCDC14 | chr3 | 123667979 | - |
| In-frame | ENST00000535302 | ENST00000310351 | SPG11 | chr15 | 44925703 | - | CCDC14 | chr3 | 123667979 | - |
| In-frame | ENST00000535302 | ENST00000488653 | SPG11 | chr15 | 44925703 | - | CCDC14 | chr3 | 123667979 | - |
| In-frame | ENST00000558319 | ENST00000310351 | SPG11 | chr15 | 44925703 | - | CCDC14 | chr3 | 123667979 | - |
| In-frame | ENST00000558319 | ENST00000488653 | SPG11 | chr15 | 44925703 | - | CCDC14 | chr3 | 123667979 | - |
| In-frame | ENST00000559193 | ENST00000310351 | SPG11 | chr15 | 44925703 | - | CCDC14 | chr3 | 123667979 | - |
| In-frame | ENST00000559193 | ENST00000488653 | SPG11 | chr15 | 44925703 | - | CCDC14 | chr3 | 123667979 | - |
| intron-3CDS | ENST00000558253 | ENST00000310351 | SPG11 | chr15 | 44925703 | - | CCDC14 | chr3 | 123667979 | - |
| intron-3CDS | ENST00000558253 | ENST00000488653 | SPG11 | chr15 | 44925703 | - | CCDC14 | chr3 | 123667979 | - |
| intron-5UTR | ENST00000558253 | ENST00000433542 | SPG11 | chr15 | 44925703 | - | CCDC14 | chr3 | 123667979 | - |
| intron-5UTR | ENST00000558253 | ENST00000485727 | SPG11 | chr15 | 44925703 | - | CCDC14 | chr3 | 123667979 | - |
| intron-5UTR | ENST00000558253 | ENST00000489746 | SPG11 | chr15 | 44925703 | - | CCDC14 | chr3 | 123667979 | - |
| intron-intron | ENST00000558253 | ENST00000483247 | SPG11 | chr15 | 44925703 | - | CCDC14 | chr3 | 123667979 | - |
| ORFfinder result based on the fusion transcript sequence of in-frame fusion genes. |
| Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | Seq length (transcript) | BP loci (transcript) | Predicted start (transcript) | Predicted stop (transcript) | Seq length (amino acids) |
| ENST00000261866 | SPG11 | chr15 | 44925703 | - | ENST00000310351 | CCDC14 | chr3 | 123667979 | - | 5444 | 1752 | 17 | 4117 | 1366 |
| ENST00000261866 | SPG11 | chr15 | 44925703 | - | ENST00000488653 | CCDC14 | chr3 | 123667979 | - | 5444 | 1752 | 17 | 4117 | 1366 |
| ENST00000535302 | SPG11 | chr15 | 44925703 | - | ENST00000310351 | CCDC14 | chr3 | 123667979 | - | 5455 | 1763 | 28 | 4128 | 1366 |
| ENST00000535302 | SPG11 | chr15 | 44925703 | - | ENST00000488653 | CCDC14 | chr3 | 123667979 | - | 5455 | 1763 | 28 | 4128 | 1366 |
| ENST00000427534 | SPG11 | chr15 | 44925703 | - | ENST00000310351 | CCDC14 | chr3 | 123667979 | - | 5427 | 1735 | 0 | 4100 | 1366 |
| ENST00000427534 | SPG11 | chr15 | 44925703 | - | ENST00000488653 | CCDC14 | chr3 | 123667979 | - | 5427 | 1735 | 0 | 4100 | 1366 |
| ENST00000558319 | SPG11 | chr15 | 44925703 | - | ENST00000310351 | CCDC14 | chr3 | 123667979 | - | 5458 | 1766 | 31 | 4131 | 1366 |
| ENST00000558319 | SPG11 | chr15 | 44925703 | - | ENST00000488653 | CCDC14 | chr3 | 123667979 | - | 5458 | 1766 | 31 | 4131 | 1366 |
| ENST00000559193 | SPG11 | chr15 | 44925703 | - | ENST00000310351 | CCDC14 | chr3 | 123667979 | - | 5438 | 1746 | 11 | 4111 | 1366 |
| ENST00000559193 | SPG11 | chr15 | 44925703 | - | ENST00000488653 | CCDC14 | chr3 | 123667979 | - | 5438 | 1746 | 11 | 4111 | 1366 |
| DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated. |
| Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | No-coding score | Coding score |
| ENST00000261866 | ENST00000310351 | SPG11 | chr15 | 44925703 | - | CCDC14 | chr3 | 123667979 | - | 0.000125747 | 0.99987423 |
| ENST00000261866 | ENST00000488653 | SPG11 | chr15 | 44925703 | - | CCDC14 | chr3 | 123667979 | - | 0.000125747 | 0.99987423 |
| ENST00000535302 | ENST00000310351 | SPG11 | chr15 | 44925703 | - | CCDC14 | chr3 | 123667979 | - | 0.000126398 | 0.99987364 |
| ENST00000535302 | ENST00000488653 | SPG11 | chr15 | 44925703 | - | CCDC14 | chr3 | 123667979 | - | 0.000126398 | 0.99987364 |
| ENST00000427534 | ENST00000310351 | SPG11 | chr15 | 44925703 | - | CCDC14 | chr3 | 123667979 | - | 0.000123926 | 0.999876 |
| ENST00000427534 | ENST00000488653 | SPG11 | chr15 | 44925703 | - | CCDC14 | chr3 | 123667979 | - | 0.000123926 | 0.999876 |
| ENST00000558319 | ENST00000310351 | SPG11 | chr15 | 44925703 | - | CCDC14 | chr3 | 123667979 | - | 0.000126371 | 0.99987364 |
| ENST00000558319 | ENST00000488653 | SPG11 | chr15 | 44925703 | - | CCDC14 | chr3 | 123667979 | - | 0.000126371 | 0.99987364 |
| ENST00000559193 | ENST00000310351 | SPG11 | chr15 | 44925703 | - | CCDC14 | chr3 | 123667979 | - | 0.00012662 | 0.9998734 |
| ENST00000559193 | ENST00000488653 | SPG11 | chr15 | 44925703 | - | CCDC14 | chr3 | 123667979 | - | 0.00012662 | 0.9998734 |
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Fusion Genomic Features for SPG11-CCDC14 |
| FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints. |
| Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | 1-p | p (fusion gene breakpoint) |
| Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page. |
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| Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page. |
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Fusion Protein Features for SPG11-CCDC14 |
| Four levels of functional features of fusion genes Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr15:44925703/chr3:123667979) - FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels. - How to search 1. Put your fusion gene symbol. 2. Press the tab key until there will be shown the breakpoint information filled. 4. Go down and press 'Search' tab twice. 4. Go down to have the hyperlink of the search result. 5. Click the hyperlink. 6. See the FGviewer result for your fusion gene. |
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| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| . | CCDC14 |
| FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Tgene | CCDC14 | chr15:44925703 | chr3:123667979 | ENST00000310351 | 0 | 9 | 383_413 | 5 | 794.0 | Coiled coil | Ontology_term=ECO:0000255 | |
| Tgene | CCDC14 | chr15:44925703 | chr3:123667979 | ENST00000310351 | 0 | 9 | 483_618 | 5 | 794.0 | Coiled coil | Ontology_term=ECO:0000255 | |
| Tgene | CCDC14 | chr15:44925703 | chr3:123667979 | ENST00000433542 | 3 | 12 | 383_413 | 124 | 913.0 | Coiled coil | Ontology_term=ECO:0000255 | |
| Tgene | CCDC14 | chr15:44925703 | chr3:123667979 | ENST00000433542 | 3 | 12 | 483_618 | 124 | 913.0 | Coiled coil | Ontology_term=ECO:0000255 | |
| Tgene | CCDC14 | chr15:44925703 | chr3:123667979 | ENST00000485727 | 0 | 9 | 383_413 | 0 | 754.0 | Coiled coil | Ontology_term=ECO:0000255 | |
| Tgene | CCDC14 | chr15:44925703 | chr3:123667979 | ENST00000485727 | 0 | 9 | 483_618 | 0 | 754.0 | Coiled coil | Ontology_term=ECO:0000255 | |
| Tgene | CCDC14 | chr15:44925703 | chr3:123667979 | ENST00000488653 | 4 | 13 | 383_413 | 165 | 954.0 | Coiled coil | Ontology_term=ECO:0000255 | |
| Tgene | CCDC14 | chr15:44925703 | chr3:123667979 | ENST00000488653 | 4 | 13 | 483_618 | 165 | 954.0 | Coiled coil | Ontology_term=ECO:0000255 | |
| Tgene | CCDC14 | chr15:44925703 | chr3:123667979 | ENST00000489746 | 0 | 9 | 383_413 | 0 | 754.0 | Coiled coil | Ontology_term=ECO:0000255 | |
| Tgene | CCDC14 | chr15:44925703 | chr3:123667979 | ENST00000489746 | 0 | 9 | 483_618 | 0 | 754.0 | Coiled coil | Ontology_term=ECO:0000255 |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
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Fusion Gene Sequence for SPG11-CCDC14 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones. |
| >85734_85734_1_SPG11-CCDC14_SPG11_chr15_44925703_ENST00000261866_CCDC14_chr3_123667979_ENST00000310351_length(transcript)=5444nt_BP=1752nt GTAACCGCCGGGCCAAGATGGCTGCAGAGGAAGGGGTCGCGAGTGCTGCTTCCGCCGGCGGTAGCTGGGGCACCGCGGCCATGGGGCGGG TTCTACCGATGCTGTTGGTGCCAGTCCCCGCCGAGGCGATGGGGCAGCTCGGCTCCCGGGCGCAGCTGCGCACACAGCCGGAGGCTCTGG GGAGCCTGACGGCTGCGGGCAGCCTCCAAGTGCTTTCTTTGACGCCTGGCAGCCGGGGCGGGGGTCGCTGCTGCCTGGAGGGCCCCTTCT GGCACTTTCTATGGGAGGATTCTCGTAACAGCAGCACACCAACTGAAAAGCCCAAACTGCTCGCTCTTGGTGAAAATTATGAACTGCTTA TCTATGAATTTAATTTGAAAGATGGAAGATGTGATGCAACCATTTTGTATAGCTGTAGTAGGGAGGCATTGCAAAAGCTCATTGACGATC AAGATATCAGTATTTCCTTATTGTCTTTGAGAATCCTGTCATTTCACAATAACACATCATTACTGTTCATCAACAAATGTGTCATCCTAC ATATTATATTTCCTGAAAGAGATGCTGCAATTAGAGTACTCAACTGTTTCACACTTCCCTTGCCTGCACAGGCAGTGGACATGATTATTG ACACGCAGCTCTGCAGAGGAATTCTTTTTGTTTTGAGTAGTTTAGGCTGGATCTACATTTTTGATGTTGTGGATGGTACATATGTAGCTC ATGTGGATTTAGCACTTCACAAAGAAGACATGTGTAATGAGCAGCAACAGGAGCCAGCCAAGATTTCTTCATTTACTTCACTGAAAGTTT CTCAAGACCTCGATGTTGCAGTGATTGTCAGCTCCTCCAACTCCGCAGTTGCTCTTAACTTAAATTTGTATTTCAGGCAACACCCAGGAC ACCTACTGTGTGAAAGAATACTAGAAGATCTTCCTATTCAAGGACCTAAGGGCGTAGATGAAGATGATCCTGTTAACTCTGCCTACAACA TGAAACTGGCCAAGTTTTCCTTCCAAATTGATAGGTCTTGGAAAGCCCAGCTATCATCATTGAATGAAACAATAAAGAACTCCAAACTGG AGGTTTCCTGTTGTGCTCCATGGTTCCAGGATATTTTGCATTTGGAGTCACCTGAATCTGGTAACCACAGTACAAGTGTGCAGAGCTGGG CCTTCATTCCACAGGACATAATGCATGGGCAATATAATGTTCTACAGAAAGATCATGCCAAGACCAGTGATCCAGGAAGATCATGGAAAA TAATGCACATCAGTGAACAAGAGGAACCCATAGAGCTTAAATGTGTGTCTGTGACAGGATTCACTGCACTGTTTACTTGGGAAGTGGAAA GGATGGGCTATACCATTACCCTCTGGGATTTGGAGACCCAGGGCATGCAGTGTTTTTCCCTTGGCACAAAGTGTATTCCTGTAGACAGTA GTGGAGACCAGCAGCTGTGCTTTGTTTTGACAGAGAATGGACTCTCTCTGATTTTGTTTGGTTTGACTCAAGAAGAGTTTTTAAACAGAC TCATGATCCATGGAAGTGCCAGCACTGTGGACACTCTTTGTCATCTCAATGGCTGGGGAAGGTGCTCAATTCCCATACATGCACTAGAGG CCGGGATAGAAAATCGTCAGCTGGACACAGTAAATTTCTTTTTGAAGAGCAAGGAAAATCTTTTTAATCCATCCTCAAAATCTTCTGTAT CTGATCAGTTTGATCACTTGTCATCCCATTTATATTTAAGAACATCTTCAGATAATAAGAAACAGATACCTAATGAAGCTTCTGCTAGAA GTGAAAGAGACACATCAGACCTAGAGCAAAACTGGTCATTGCAAGATCATTATAGAATGTATTCACCCATAATATACCAAGCCCTCTGTG AGCACGTGCAGACTCAGATGTCACTGATGAATGACTTGACTTCAAAGAACATCCCTAATGGAATTCCTGCTGTACCATGCCATGCTCCCT CTCATTCTGAATCTCAGGCAACTCCTCATTCTAGTTATGGCTTATGTACCTCCACCCCAGTCTGGTCACTTCAGCGGCCACCCTGCCCTC CAAAGGTTCATTCTGAAGTTCAAACTGATGGCAACAGTCAGTTTGCATCACAAGGTAAAACAGTTTCTGCAACCTGTACTGATGTTCTAC GGAATTCATTTAATACCAGTCCTGGAGTTCCATGTAGCCTGCCCAAAACTGACATATCAGCTATTCCAACATTGCAGCAACTGGGCCTTG TTAATGGAATTCTGCCACAACAAGGAATTCATAAGGAAACAGACCTACTAAAATGTATTCAAACATATTTGTCTCTTTTTCGATCTCATG GAAAAGAAACGCATCTGGACAGTCAGACACACCGAAGCCCTACTCAGTCACAACCAGCTTTCTTGGCCACTAATGAAGAAAAATGTGCCA GAGAGCAAATTAGAGAGGCCACAAGTGAAAGAAAGGATTTAAACATACATGTGCGAGATACAAAAACAGTGAAGGATGTACAGAAGGCAA AAAATGTGAACAAGACAGCTGAAAAAGTTAGAATTATAAAATATTTGTTGGGAGAGCTCAAGGCCCTGGTAGCAGAACAAGAGGATTCAG AAATTCAGAGGTTGATTACAGAAATGGAGGCATGTATATCTGTACTTCCAACAGTAAGTGGAAACACAGATATTCAAGTTGAGATAGCAC TGGCCATGCAACCATTAAGAAGTGAGAATGCTCAGTTACGAAGGCAGTTGAGAATTTTGAACCAGCAACTCAGAGAACAACAGAAAACTC AAAAACCATCTGGTGCTGTGGATTGCAACCTTGAATTGTTTTCTCTTCAGTCATTGAATATGTCACTGCAAAATCAATTGGAGGAGTCAC TAAAGAGCCAGGAATTACTGCAGAGTAAAAATGAAGAGCTGTTAAAAGTGATTGAAAATCAGAAAGATGAAAACAAAAAATTTAGTAGTA TATTTAAAGACAAAGATCAAACTATACTTGAAAATAAACAGCAATATGATATTGAGATAACAAGAATAAAAATTGAATTGGAGGAAGCCC TAGTCAATGTGAAAAGCTCCCAGTTTAAGTTAGAAACTGCTGAAAAGGAAAACCAGATATTGGGGATAACATTACGTCAGCGTGATGCTG AGGTGACTCGACTAAGAGAATTAACCAGAACTTTACAGACTAGCATGGCAAAGCTTCTCTCCGATCTTAGTGTGGACAGTGCTCGCTGCA AGCCTGGGAATAACCTTACCAAATCACTCTTGAACATTCATGATAAACAACTTCAACATGACCCAGCTCCTGCTCACACTTCCATAATGA GCTATCTAAATAAGTTAGAAACAAATTACAGTTTTACACATTCAGAGCCACTTTCTACAATTAAAAATGAGGAAACCATAGAGCCAGACA AAACCTATGAAAATGTTCTGTCCTCCAGAGGCCCTCAAAATAGTAACACTAGGGGCATGGAGGAAGCATCTGCACCTGGAATTATTTCTG CCCTTTCAAAACAGGATTCTGATGAAGGGAGTGAAACTATGGCTTTAATAGAAGATGAGCATAATTTGGATAATACAATTTACATTCCTT TTGCTAGAAGCACTCCTGAAAAGAAATCACCACTTTCTAAGAGACTATCCCCTCAGCCACAAATAAGAGCAGCTACAACACAGCTAGTCA GCAACAGCGGACTTGCTGTCTCTGGAAAAGAAAATAAACTGTGTACACCTGTAATCTGTTCCTCTTCAACAAAGGAAGCAGAAGATGCAC CTGAAAAACTTTCCAGAGCATCTGATATGAAGGACACACAGCTCCTCAAGAAAATAAAGGAAGCAATTGGTAAGATCCCTGCTGCCACCA AGGAGCCAGAGGAACAAACTGCATGTCATGGCCCATCAGGTTGTCTTAGCAACAGCCTTCAAGTGAAAGGCAATACTGTCTGTGATGGTA GTGTTTTCACTTCTGACTTGATGTCTGACTGGAGCATCTCTTCGTTTTCAACGTTCACTTCTCGTGATGAACAAGACTTCAGAAATGGCC TTGCGGCATTAGATGCCAACATAGCTAGACTCCAGAAGTCTTTAAGGACTGGTCTTCTGGAGAAATGAATTCAGAAGAAAACTCATCAGG TGCTTCTTTTTAAAACTAGAACTTGGCTATATTGAATGTGTATTTTTCTTTAGTGAAATGATGTTTTATGTTATTATGTGTGAAGTAATA TATTGTACAAGTAATAAATGTATTGTTGAGATATATTGACACTGAGGAGCTTATAAAAACAAGTCATCTTAAGTTCACAATTGCTACAAG AAGAAAGTTGTGGATAACTAGGAAATTATTGTAAGTAATGTTTTATTTCAGTACTTAGCAATTAGAGTTCTTTTATTAAGATGTATCTGC TGGATTAAGGGTACAGGTTGAAATAGTTCTGTGGCTGTCCTAAGAAATAATGGGAAAAGAATCTCTGGATGTAAGTTTTTCTGTTGAAAC TAGAGGGTTTTTTTTTTCTGTTTACATATACTTTTTTTTAATAGCAATGTGTTTTTATTAAACATGCTGTGTGCCACAGGCCAGTGTTGT TGGTGAAATATATAAACATTTATTTAAAGAGAAAAGTTACCAGTATCTACACCTCTTAAAAAACATTGATTGGTCTAAAAAATATATAGA TAACATCCTAAGTTAACATATGGCTTCTTAAAACTTGGGCACTTTTATTTGTTTTTATCCCAAATTCATGTTTTAAGGCCTTTAAAGAAT AGTCAGACTGATAAAGAAGTGCTAACAGATAAGCTATAGTTGGGGAAATTTGTGGGTTTTTTTTAAATAAGAAATGTTTATTTTTGTCCT TATATTTAAACATGATGGAATTTGTAAATCTTGGCATTGATTGTAATTCTGCCTTTTTGGAAGAATTTTTTCTCCCAGCATGTTAGCTGA GAATATTCTCTATTTTATAAATAATATGAAGTAGGTTGGTCTCTCTGCTTCTCTATACCAGGACTTCTTAGCTCAGTATCATCTCCCTTC ATGTAAGCAGCACGTTTTAACTCTTAGGAAGCTGAATGTTGTGTTATCACTAATACTTTGTACAGGTCACCTGCCTACTCTAATTGTCCT TAGTACTTGGACAGGCTTTATCATTAAAGAGTGTTCTCCTAATCCCAGAACCTCCTCGTGTTTTTTGTTTTTTTGGTGGTTTTTTTTTTT TTTTTAGGTGTTAGTGCTACAGCGTTTGAAGGAGCCAGCTGTAGTCTCTTTGATATGTTCAGATTTTCCAGATAGAGATTTAAGTCTAAA AATTTATTAAGTGAATTCTAAACTATTTCACACAAGAGTCCATTAGCATCTTTAATTTTATTTAGTATTCATGAATTAATTTATTGGCAT >85734_85734_1_SPG11-CCDC14_SPG11_chr15_44925703_ENST00000261866_CCDC14_chr3_123667979_ENST00000310351_length(amino acids)=1366AA_BP=579 MAAEEGVASAASAGGSWGTAAMGRVLPMLLVPVPAEAMGQLGSRAQLRTQPEALGSLTAAGSLQVLSLTPGSRGGGRCCLEGPFWHFLWE DSRNSSTPTEKPKLLALGENYELLIYEFNLKDGRCDATILYSCSREALQKLIDDQDISISLLSLRILSFHNNTSLLFINKCVILHIIFPE RDAAIRVLNCFTLPLPAQAVDMIIDTQLCRGILFVLSSLGWIYIFDVVDGTYVAHVDLALHKEDMCNEQQQEPAKISSFTSLKVSQDLDV AVIVSSSNSAVALNLNLYFRQHPGHLLCERILEDLPIQGPKGVDEDDPVNSAYNMKLAKFSFQIDRSWKAQLSSLNETIKNSKLEVSCCA PWFQDILHLESPESGNHSTSVQSWAFIPQDIMHGQYNVLQKDHAKTSDPGRSWKIMHISEQEEPIELKCVSVTGFTALFTWEVERMGYTI TLWDLETQGMQCFSLGTKCIPVDSSGDQQLCFVLTENGLSLILFGLTQEEFLNRLMIHGSASTVDTLCHLNGWGRCSIPIHALEAGIENR QLDTVNFFLKSKENLFNPSSKSSVSDQFDHLSSHLYLRTSSDNKKQIPNEASARSERDTSDLEQNWSLQDHYRMYSPIIYQALCEHVQTQ MSLMNDLTSKNIPNGIPAVPCHAPSHSESQATPHSSYGLCTSTPVWSLQRPPCPPKVHSEVQTDGNSQFASQGKTVSATCTDVLRNSFNT SPGVPCSLPKTDISAIPTLQQLGLVNGILPQQGIHKETDLLKCIQTYLSLFRSHGKETHLDSQTHRSPTQSQPAFLATNEEKCAREQIRE ATSERKDLNIHVRDTKTVKDVQKAKNVNKTAEKVRIIKYLLGELKALVAEQEDSEIQRLITEMEACISVLPTVSGNTDIQVEIALAMQPL RSENAQLRRQLRILNQQLREQQKTQKPSGAVDCNLELFSLQSLNMSLQNQLEESLKSQELLQSKNEELLKVIENQKDENKKFSSIFKDKD QTILENKQQYDIEITRIKIELEEALVNVKSSQFKLETAEKENQILGITLRQRDAEVTRLRELTRTLQTSMAKLLSDLSVDSARCKPGNNL TKSLLNIHDKQLQHDPAPAHTSIMSYLNKLETNYSFTHSEPLSTIKNEETIEPDKTYENVLSSRGPQNSNTRGMEEASAPGIISALSKQD SDEGSETMALIEDEHNLDNTIYIPFARSTPEKKSPLSKRLSPQPQIRAATTQLVSNSGLAVSGKENKLCTPVICSSSTKEAEDAPEKLSR ASDMKDTQLLKKIKEAIGKIPAATKEPEEQTACHGPSGCLSNSLQVKGNTVCDGSVFTSDLMSDWSISSFSTFTSRDEQDFRNGLAALDA -------------------------------------------------------------- >85734_85734_2_SPG11-CCDC14_SPG11_chr15_44925703_ENST00000261866_CCDC14_chr3_123667979_ENST00000488653_length(transcript)=5444nt_BP=1752nt GTAACCGCCGGGCCAAGATGGCTGCAGAGGAAGGGGTCGCGAGTGCTGCTTCCGCCGGCGGTAGCTGGGGCACCGCGGCCATGGGGCGGG TTCTACCGATGCTGTTGGTGCCAGTCCCCGCCGAGGCGATGGGGCAGCTCGGCTCCCGGGCGCAGCTGCGCACACAGCCGGAGGCTCTGG GGAGCCTGACGGCTGCGGGCAGCCTCCAAGTGCTTTCTTTGACGCCTGGCAGCCGGGGCGGGGGTCGCTGCTGCCTGGAGGGCCCCTTCT GGCACTTTCTATGGGAGGATTCTCGTAACAGCAGCACACCAACTGAAAAGCCCAAACTGCTCGCTCTTGGTGAAAATTATGAACTGCTTA TCTATGAATTTAATTTGAAAGATGGAAGATGTGATGCAACCATTTTGTATAGCTGTAGTAGGGAGGCATTGCAAAAGCTCATTGACGATC AAGATATCAGTATTTCCTTATTGTCTTTGAGAATCCTGTCATTTCACAATAACACATCATTACTGTTCATCAACAAATGTGTCATCCTAC ATATTATATTTCCTGAAAGAGATGCTGCAATTAGAGTACTCAACTGTTTCACACTTCCCTTGCCTGCACAGGCAGTGGACATGATTATTG ACACGCAGCTCTGCAGAGGAATTCTTTTTGTTTTGAGTAGTTTAGGCTGGATCTACATTTTTGATGTTGTGGATGGTACATATGTAGCTC ATGTGGATTTAGCACTTCACAAAGAAGACATGTGTAATGAGCAGCAACAGGAGCCAGCCAAGATTTCTTCATTTACTTCACTGAAAGTTT CTCAAGACCTCGATGTTGCAGTGATTGTCAGCTCCTCCAACTCCGCAGTTGCTCTTAACTTAAATTTGTATTTCAGGCAACACCCAGGAC ACCTACTGTGTGAAAGAATACTAGAAGATCTTCCTATTCAAGGACCTAAGGGCGTAGATGAAGATGATCCTGTTAACTCTGCCTACAACA TGAAACTGGCCAAGTTTTCCTTCCAAATTGATAGGTCTTGGAAAGCCCAGCTATCATCATTGAATGAAACAATAAAGAACTCCAAACTGG AGGTTTCCTGTTGTGCTCCATGGTTCCAGGATATTTTGCATTTGGAGTCACCTGAATCTGGTAACCACAGTACAAGTGTGCAGAGCTGGG CCTTCATTCCACAGGACATAATGCATGGGCAATATAATGTTCTACAGAAAGATCATGCCAAGACCAGTGATCCAGGAAGATCATGGAAAA TAATGCACATCAGTGAACAAGAGGAACCCATAGAGCTTAAATGTGTGTCTGTGACAGGATTCACTGCACTGTTTACTTGGGAAGTGGAAA GGATGGGCTATACCATTACCCTCTGGGATTTGGAGACCCAGGGCATGCAGTGTTTTTCCCTTGGCACAAAGTGTATTCCTGTAGACAGTA GTGGAGACCAGCAGCTGTGCTTTGTTTTGACAGAGAATGGACTCTCTCTGATTTTGTTTGGTTTGACTCAAGAAGAGTTTTTAAACAGAC TCATGATCCATGGAAGTGCCAGCACTGTGGACACTCTTTGTCATCTCAATGGCTGGGGAAGGTGCTCAATTCCCATACATGCACTAGAGG CCGGGATAGAAAATCGTCAGCTGGACACAGTAAATTTCTTTTTGAAGAGCAAGGAAAATCTTTTTAATCCATCCTCAAAATCTTCTGTAT CTGATCAGTTTGATCACTTGTCATCCCATTTATATTTAAGAACATCTTCAGATAATAAGAAACAGATACCTAATGAAGCTTCTGCTAGAA GTGAAAGAGACACATCAGACCTAGAGCAAAACTGGTCATTGCAAGATCATTATAGAATGTATTCACCCATAATATACCAAGCCCTCTGTG AGCACGTGCAGACTCAGATGTCACTGATGAATGACTTGACTTCAAAGAACATCCCTAATGGAATTCCTGCTGTACCATGCCATGCTCCCT CTCATTCTGAATCTCAGGCAACTCCTCATTCTAGTTATGGCTTATGTACCTCCACCCCAGTCTGGTCACTTCAGCGGCCACCCTGCCCTC CAAAGGTTCATTCTGAAGTTCAAACTGATGGCAACAGTCAGTTTGCATCACAAGGTAAAACAGTTTCTGCAACCTGTACTGATGTTCTAC GGAATTCATTTAATACCAGTCCTGGAGTTCCATGTAGCCTGCCCAAAACTGACATATCAGCTATTCCAACATTGCAGCAACTGGGCCTTG TTAATGGAATTCTGCCACAACAAGGAATTCATAAGGAAACAGACCTACTAAAATGTATTCAAACATATTTGTCTCTTTTTCGATCTCATG GAAAAGAAACGCATCTGGACAGTCAGACACACCGAAGCCCTACTCAGTCACAACCAGCTTTCTTGGCCACTAATGAAGAAAAATGTGCCA GAGAGCAAATTAGAGAGGCCACAAGTGAAAGAAAGGATTTAAACATACATGTGCGAGATACAAAAACAGTGAAGGATGTACAGAAGGCAA AAAATGTGAACAAGACAGCTGAAAAAGTTAGAATTATAAAATATTTGTTGGGAGAGCTCAAGGCCCTGGTAGCAGAACAAGAGGATTCAG AAATTCAGAGGTTGATTACAGAAATGGAGGCATGTATATCTGTACTTCCAACAGTAAGTGGAAACACAGATATTCAAGTTGAGATAGCAC TGGCCATGCAACCATTAAGAAGTGAGAATGCTCAGTTACGAAGGCAGTTGAGAATTTTGAACCAGCAACTCAGAGAACAACAGAAAACTC AAAAACCATCTGGTGCTGTGGATTGCAACCTTGAATTGTTTTCTCTTCAGTCATTGAATATGTCACTGCAAAATCAATTGGAGGAGTCAC TAAAGAGCCAGGAATTACTGCAGAGTAAAAATGAAGAGCTGTTAAAAGTGATTGAAAATCAGAAAGATGAAAACAAAAAATTTAGTAGTA TATTTAAAGACAAAGATCAAACTATACTTGAAAATAAACAGCAATATGATATTGAGATAACAAGAATAAAAATTGAATTGGAGGAAGCCC TAGTCAATGTGAAAAGCTCCCAGTTTAAGTTAGAAACTGCTGAAAAGGAAAACCAGATATTGGGGATAACATTACGTCAGCGTGATGCTG AGGTGACTCGACTAAGAGAATTAACCAGAACTTTACAGACTAGCATGGCAAAGCTTCTCTCCGATCTTAGTGTGGACAGTGCTCGCTGCA AGCCTGGGAATAACCTTACCAAATCACTCTTGAACATTCATGATAAACAACTTCAACATGACCCAGCTCCTGCTCACACTTCCATAATGA GCTATCTAAATAAGTTAGAAACAAATTACAGTTTTACACATTCAGAGCCACTTTCTACAATTAAAAATGAGGAAACCATAGAGCCAGACA AAACCTATGAAAATGTTCTGTCCTCCAGAGGCCCTCAAAATAGTAACACTAGGGGCATGGAGGAAGCATCTGCACCTGGAATTATTTCTG CCCTTTCAAAACAGGATTCTGATGAAGGGAGTGAAACTATGGCTTTAATAGAAGATGAGCATAATTTGGATAATACAATTTACATTCCTT TTGCTAGAAGCACTCCTGAAAAGAAATCACCACTTTCTAAGAGACTATCCCCTCAGCCACAAATAAGAGCAGCTACAACACAGCTAGTCA GCAACAGCGGACTTGCTGTCTCTGGAAAAGAAAATAAACTGTGTACACCTGTAATCTGTTCCTCTTCAACAAAGGAAGCAGAAGATGCAC CTGAAAAACTTTCCAGAGCATCTGATATGAAGGACACACAGCTCCTCAAGAAAATAAAGGAAGCAATTGGTAAGATCCCTGCTGCCACCA AGGAGCCAGAGGAACAAACTGCATGTCATGGCCCATCAGGTTGTCTTAGCAACAGCCTTCAAGTGAAAGGCAATACTGTCTGTGATGGTA GTGTTTTCACTTCTGACTTGATGTCTGACTGGAGCATCTCTTCGTTTTCAACGTTCACTTCTCGTGATGAACAAGACTTCAGAAATGGCC TTGCGGCATTAGATGCCAACATAGCTAGACTCCAGAAGTCTTTAAGGACTGGTCTTCTGGAGAAATGAATTCAGAAGAAAACTCATCAGG TGCTTCTTTTTAAAACTAGAACTTGGCTATATTGAATGTGTATTTTTCTTTAGTGAAATGATGTTTTATGTTATTATGTGTGAAGTAATA TATTGTACAAGTAATAAATGTATTGTTGAGATATATTGACACTGAGGAGCTTATAAAAACAAGTCATCTTAAGTTCACAATTGCTACAAG AAGAAAGTTGTGGATAACTAGGAAATTATTGTAAGTAATGTTTTATTTCAGTACTTAGCAATTAGAGTTCTTTTATTAAGATGTATCTGC TGGATTAAGGGTACAGGTTGAAATAGTTCTGTGGCTGTCCTAAGAAATAATGGGAAAAGAATCTCTGGATGTAAGTTTTTCTGTTGAAAC TAGAGGGTTTTTTTTTTCTGTTTACATATACTTTTTTTTAATAGCAATGTGTTTTTATTAAACATGCTGTGTGCCACAGGCCAGTGTTGT TGGTGAAATATATAAACATTTATTTAAAGAGAAAAGTTACCAGTATCTACACCTCTTAAAAAACATTGATTGGTCTAAAAAATATATAGA TAACATCCTAAGTTAACATATGGCTTCTTAAAACTTGGGCACTTTTATTTGTTTTTATCCCAAATTCATGTTTTAAGGCCTTTAAAGAAT AGTCAGACTGATAAAGAAGTGCTAACAGATAAGCTATAGTTGGGGAAATTTGTGGGTTTTTTTTAAATAAGAAATGTTTATTTTTGTCCT TATATTTAAACATGATGGAATTTGTAAATCTTGGCATTGATTGTAATTCTGCCTTTTTGGAAGAATTTTTTCTCCCAGCATGTTAGCTGA GAATATTCTCTATTTTATAAATAATATGAAGTAGGTTGGTCTCTCTGCTTCTCTATACCAGGACTTCTTAGCTCAGTATCATCTCCCTTC ATGTAAGCAGCACGTTTTAACTCTTAGGAAGCTGAATGTTGTGTTATCACTAATACTTTGTACAGGTCACCTGCCTACTCTAATTGTCCT TAGTACTTGGACAGGCTTTATCATTAAAGAGTGTTCTCCTAATCCCAGAACCTCCTCGTGTTTTTTGTTTTTTTGGTGGTTTTTTTTTTT TTTTTAGGTGTTAGTGCTACAGCGTTTGAAGGAGCCAGCTGTAGTCTCTTTGATATGTTCAGATTTTCCAGATAGAGATTTAAGTCTAAA AATTTATTAAGTGAATTCTAAACTATTTCACACAAGAGTCCATTAGCATCTTTAATTTTATTTAGTATTCATGAATTAATTTATTGGCAT >85734_85734_2_SPG11-CCDC14_SPG11_chr15_44925703_ENST00000261866_CCDC14_chr3_123667979_ENST00000488653_length(amino acids)=1366AA_BP=579 MAAEEGVASAASAGGSWGTAAMGRVLPMLLVPVPAEAMGQLGSRAQLRTQPEALGSLTAAGSLQVLSLTPGSRGGGRCCLEGPFWHFLWE DSRNSSTPTEKPKLLALGENYELLIYEFNLKDGRCDATILYSCSREALQKLIDDQDISISLLSLRILSFHNNTSLLFINKCVILHIIFPE RDAAIRVLNCFTLPLPAQAVDMIIDTQLCRGILFVLSSLGWIYIFDVVDGTYVAHVDLALHKEDMCNEQQQEPAKISSFTSLKVSQDLDV AVIVSSSNSAVALNLNLYFRQHPGHLLCERILEDLPIQGPKGVDEDDPVNSAYNMKLAKFSFQIDRSWKAQLSSLNETIKNSKLEVSCCA PWFQDILHLESPESGNHSTSVQSWAFIPQDIMHGQYNVLQKDHAKTSDPGRSWKIMHISEQEEPIELKCVSVTGFTALFTWEVERMGYTI TLWDLETQGMQCFSLGTKCIPVDSSGDQQLCFVLTENGLSLILFGLTQEEFLNRLMIHGSASTVDTLCHLNGWGRCSIPIHALEAGIENR QLDTVNFFLKSKENLFNPSSKSSVSDQFDHLSSHLYLRTSSDNKKQIPNEASARSERDTSDLEQNWSLQDHYRMYSPIIYQALCEHVQTQ MSLMNDLTSKNIPNGIPAVPCHAPSHSESQATPHSSYGLCTSTPVWSLQRPPCPPKVHSEVQTDGNSQFASQGKTVSATCTDVLRNSFNT SPGVPCSLPKTDISAIPTLQQLGLVNGILPQQGIHKETDLLKCIQTYLSLFRSHGKETHLDSQTHRSPTQSQPAFLATNEEKCAREQIRE ATSERKDLNIHVRDTKTVKDVQKAKNVNKTAEKVRIIKYLLGELKALVAEQEDSEIQRLITEMEACISVLPTVSGNTDIQVEIALAMQPL RSENAQLRRQLRILNQQLREQQKTQKPSGAVDCNLELFSLQSLNMSLQNQLEESLKSQELLQSKNEELLKVIENQKDENKKFSSIFKDKD QTILENKQQYDIEITRIKIELEEALVNVKSSQFKLETAEKENQILGITLRQRDAEVTRLRELTRTLQTSMAKLLSDLSVDSARCKPGNNL TKSLLNIHDKQLQHDPAPAHTSIMSYLNKLETNYSFTHSEPLSTIKNEETIEPDKTYENVLSSRGPQNSNTRGMEEASAPGIISALSKQD SDEGSETMALIEDEHNLDNTIYIPFARSTPEKKSPLSKRLSPQPQIRAATTQLVSNSGLAVSGKENKLCTPVICSSSTKEAEDAPEKLSR ASDMKDTQLLKKIKEAIGKIPAATKEPEEQTACHGPSGCLSNSLQVKGNTVCDGSVFTSDLMSDWSISSFSTFTSRDEQDFRNGLAALDA -------------------------------------------------------------- >85734_85734_3_SPG11-CCDC14_SPG11_chr15_44925703_ENST00000427534_CCDC14_chr3_123667979_ENST00000310351_length(transcript)=5427nt_BP=1735nt ATGGCTGCAGAGGAAGGGGTCGCGAGTGCTGCTTCCGCCGGCGGTAGCTGGGGCACCGCGGCCATGGGGCGGGTTCTACCGATGCTGTTG GTGCCAGTCCCCGCCGAGGCGATGGGGCAGCTCGGCTCCCGGGCGCAGCTGCGCACACAGCCGGAGGCTCTGGGGAGCCTGACGGCTGCG GGCAGCCTCCAAGTGCTTTCTTTGACGCCTGGCAGCCGGGGCGGGGGTCGCTGCTGCCTGGAGGGCCCCTTCTGGCACTTTCTATGGGAG GATTCTCGTAACAGCAGCACACCAACTGAAAAGCCCAAACTGCTCGCTCTTGGTGAAAATTATGAACTGCTTATCTATGAATTTAATTTG AAAGATGGAAGATGTGATGCAACCATTTTGTATAGCTGTAGTAGGGAGGCATTGCAAAAGCTCATTGACGATCAAGATATCAGTATTTCC TTATTGTCTTTGAGAATCCTGTCATTTCACAATAACACATCATTACTGTTCATCAACAAATGTGTCATCCTACATATTATATTTCCTGAA AGAGATGCTGCAATTAGAGTACTCAACTGTTTCACACTTCCCTTGCCTGCACAGGCAGTGGACATGATTATTGACACGCAGCTCTGCAGA GGAATTCTTTTTGTTTTGAGTAGTTTAGGCTGGATCTACATTTTTGATGTTGTGGATGGTACATATGTAGCTCATGTGGATTTAGCACTT CACAAAGAAGACATGTGTAATGAGCAGCAACAGGAGCCAGCCAAGATTTCTTCATTTACTTCACTGAAAGTTTCTCAAGACCTCGATGTT GCAGTGATTGTCAGCTCCTCCAACTCCGCAGTTGCTCTTAACTTAAATTTGTATTTCAGGCAACACCCAGGACACCTACTGTGTGAAAGA ATACTAGAAGATCTTCCTATTCAAGGACCTAAGGGCGTAGATGAAGATGATCCTGTTAACTCTGCCTACAACATGAAACTGGCCAAGTTT TCCTTCCAAATTGATAGGTCTTGGAAAGCCCAGCTATCATCATTGAATGAAACAATAAAGAACTCCAAACTGGAGGTTTCCTGTTGTGCT CCATGGTTCCAGGATATTTTGCATTTGGAGTCACCTGAATCTGGTAACCACAGTACAAGTGTGCAGAGCTGGGCCTTCATTCCACAGGAC ATAATGCATGGGCAATATAATGTTCTACAGAAAGATCATGCCAAGACCAGTGATCCAGGAAGATCATGGAAAATAATGCACATCAGTGAA CAAGAGGAACCCATAGAGCTTAAATGTGTGTCTGTGACAGGATTCACTGCACTGTTTACTTGGGAAGTGGAAAGGATGGGCTATACCATT ACCCTCTGGGATTTGGAGACCCAGGGCATGCAGTGTTTTTCCCTTGGCACAAAGTGTATTCCTGTAGACAGTAGTGGAGACCAGCAGCTG TGCTTTGTTTTGACAGAGAATGGACTCTCTCTGATTTTGTTTGGTTTGACTCAAGAAGAGTTTTTAAACAGACTCATGATCCATGGAAGT GCCAGCACTGTGGACACTCTTTGTCATCTCAATGGCTGGGGAAGGTGCTCAATTCCCATACATGCACTAGAGGCCGGGATAGAAAATCGT CAGCTGGACACAGTAAATTTCTTTTTGAAGAGCAAGGAAAATCTTTTTAATCCATCCTCAAAATCTTCTGTATCTGATCAGTTTGATCAC TTGTCATCCCATTTATATTTAAGAACATCTTCAGATAATAAGAAACAGATACCTAATGAAGCTTCTGCTAGAAGTGAAAGAGACACATCA GACCTAGAGCAAAACTGGTCATTGCAAGATCATTATAGAATGTATTCACCCATAATATACCAAGCCCTCTGTGAGCACGTGCAGACTCAG ATGTCACTGATGAATGACTTGACTTCAAAGAACATCCCTAATGGAATTCCTGCTGTACCATGCCATGCTCCCTCTCATTCTGAATCTCAG GCAACTCCTCATTCTAGTTATGGCTTATGTACCTCCACCCCAGTCTGGTCACTTCAGCGGCCACCCTGCCCTCCAAAGGTTCATTCTGAA GTTCAAACTGATGGCAACAGTCAGTTTGCATCACAAGGTAAAACAGTTTCTGCAACCTGTACTGATGTTCTACGGAATTCATTTAATACC AGTCCTGGAGTTCCATGTAGCCTGCCCAAAACTGACATATCAGCTATTCCAACATTGCAGCAACTGGGCCTTGTTAATGGAATTCTGCCA CAACAAGGAATTCATAAGGAAACAGACCTACTAAAATGTATTCAAACATATTTGTCTCTTTTTCGATCTCATGGAAAAGAAACGCATCTG GACAGTCAGACACACCGAAGCCCTACTCAGTCACAACCAGCTTTCTTGGCCACTAATGAAGAAAAATGTGCCAGAGAGCAAATTAGAGAG GCCACAAGTGAAAGAAAGGATTTAAACATACATGTGCGAGATACAAAAACAGTGAAGGATGTACAGAAGGCAAAAAATGTGAACAAGACA GCTGAAAAAGTTAGAATTATAAAATATTTGTTGGGAGAGCTCAAGGCCCTGGTAGCAGAACAAGAGGATTCAGAAATTCAGAGGTTGATT ACAGAAATGGAGGCATGTATATCTGTACTTCCAACAGTAAGTGGAAACACAGATATTCAAGTTGAGATAGCACTGGCCATGCAACCATTA AGAAGTGAGAATGCTCAGTTACGAAGGCAGTTGAGAATTTTGAACCAGCAACTCAGAGAACAACAGAAAACTCAAAAACCATCTGGTGCT GTGGATTGCAACCTTGAATTGTTTTCTCTTCAGTCATTGAATATGTCACTGCAAAATCAATTGGAGGAGTCACTAAAGAGCCAGGAATTA CTGCAGAGTAAAAATGAAGAGCTGTTAAAAGTGATTGAAAATCAGAAAGATGAAAACAAAAAATTTAGTAGTATATTTAAAGACAAAGAT CAAACTATACTTGAAAATAAACAGCAATATGATATTGAGATAACAAGAATAAAAATTGAATTGGAGGAAGCCCTAGTCAATGTGAAAAGC TCCCAGTTTAAGTTAGAAACTGCTGAAAAGGAAAACCAGATATTGGGGATAACATTACGTCAGCGTGATGCTGAGGTGACTCGACTAAGA GAATTAACCAGAACTTTACAGACTAGCATGGCAAAGCTTCTCTCCGATCTTAGTGTGGACAGTGCTCGCTGCAAGCCTGGGAATAACCTT ACCAAATCACTCTTGAACATTCATGATAAACAACTTCAACATGACCCAGCTCCTGCTCACACTTCCATAATGAGCTATCTAAATAAGTTA GAAACAAATTACAGTTTTACACATTCAGAGCCACTTTCTACAATTAAAAATGAGGAAACCATAGAGCCAGACAAAACCTATGAAAATGTT CTGTCCTCCAGAGGCCCTCAAAATAGTAACACTAGGGGCATGGAGGAAGCATCTGCACCTGGAATTATTTCTGCCCTTTCAAAACAGGAT TCTGATGAAGGGAGTGAAACTATGGCTTTAATAGAAGATGAGCATAATTTGGATAATACAATTTACATTCCTTTTGCTAGAAGCACTCCT GAAAAGAAATCACCACTTTCTAAGAGACTATCCCCTCAGCCACAAATAAGAGCAGCTACAACACAGCTAGTCAGCAACAGCGGACTTGCT GTCTCTGGAAAAGAAAATAAACTGTGTACACCTGTAATCTGTTCCTCTTCAACAAAGGAAGCAGAAGATGCACCTGAAAAACTTTCCAGA GCATCTGATATGAAGGACACACAGCTCCTCAAGAAAATAAAGGAAGCAATTGGTAAGATCCCTGCTGCCACCAAGGAGCCAGAGGAACAA ACTGCATGTCATGGCCCATCAGGTTGTCTTAGCAACAGCCTTCAAGTGAAAGGCAATACTGTCTGTGATGGTAGTGTTTTCACTTCTGAC TTGATGTCTGACTGGAGCATCTCTTCGTTTTCAACGTTCACTTCTCGTGATGAACAAGACTTCAGAAATGGCCTTGCGGCATTAGATGCC AACATAGCTAGACTCCAGAAGTCTTTAAGGACTGGTCTTCTGGAGAAATGAATTCAGAAGAAAACTCATCAGGTGCTTCTTTTTAAAACT AGAACTTGGCTATATTGAATGTGTATTTTTCTTTAGTGAAATGATGTTTTATGTTATTATGTGTGAAGTAATATATTGTACAAGTAATAA ATGTATTGTTGAGATATATTGACACTGAGGAGCTTATAAAAACAAGTCATCTTAAGTTCACAATTGCTACAAGAAGAAAGTTGTGGATAA CTAGGAAATTATTGTAAGTAATGTTTTATTTCAGTACTTAGCAATTAGAGTTCTTTTATTAAGATGTATCTGCTGGATTAAGGGTACAGG TTGAAATAGTTCTGTGGCTGTCCTAAGAAATAATGGGAAAAGAATCTCTGGATGTAAGTTTTTCTGTTGAAACTAGAGGGTTTTTTTTTT CTGTTTACATATACTTTTTTTTAATAGCAATGTGTTTTTATTAAACATGCTGTGTGCCACAGGCCAGTGTTGTTGGTGAAATATATAAAC ATTTATTTAAAGAGAAAAGTTACCAGTATCTACACCTCTTAAAAAACATTGATTGGTCTAAAAAATATATAGATAACATCCTAAGTTAAC ATATGGCTTCTTAAAACTTGGGCACTTTTATTTGTTTTTATCCCAAATTCATGTTTTAAGGCCTTTAAAGAATAGTCAGACTGATAAAGA AGTGCTAACAGATAAGCTATAGTTGGGGAAATTTGTGGGTTTTTTTTAAATAAGAAATGTTTATTTTTGTCCTTATATTTAAACATGATG GAATTTGTAAATCTTGGCATTGATTGTAATTCTGCCTTTTTGGAAGAATTTTTTCTCCCAGCATGTTAGCTGAGAATATTCTCTATTTTA TAAATAATATGAAGTAGGTTGGTCTCTCTGCTTCTCTATACCAGGACTTCTTAGCTCAGTATCATCTCCCTTCATGTAAGCAGCACGTTT TAACTCTTAGGAAGCTGAATGTTGTGTTATCACTAATACTTTGTACAGGTCACCTGCCTACTCTAATTGTCCTTAGTACTTGGACAGGCT TTATCATTAAAGAGTGTTCTCCTAATCCCAGAACCTCCTCGTGTTTTTTGTTTTTTTGGTGGTTTTTTTTTTTTTTTTAGGTGTTAGTGC TACAGCGTTTGAAGGAGCCAGCTGTAGTCTCTTTGATATGTTCAGATTTTCCAGATAGAGATTTAAGTCTAAAAATTTATTAAGTGAATT CTAAACTATTTCACACAAGAGTCCATTAGCATCTTTAATTTTATTTAGTATTCATGAATTAATTTATTGGCATCTTATTTGGAGGTAATA >85734_85734_3_SPG11-CCDC14_SPG11_chr15_44925703_ENST00000427534_CCDC14_chr3_123667979_ENST00000310351_length(amino acids)=1366AA_BP=579 MAAEEGVASAASAGGSWGTAAMGRVLPMLLVPVPAEAMGQLGSRAQLRTQPEALGSLTAAGSLQVLSLTPGSRGGGRCCLEGPFWHFLWE DSRNSSTPTEKPKLLALGENYELLIYEFNLKDGRCDATILYSCSREALQKLIDDQDISISLLSLRILSFHNNTSLLFINKCVILHIIFPE RDAAIRVLNCFTLPLPAQAVDMIIDTQLCRGILFVLSSLGWIYIFDVVDGTYVAHVDLALHKEDMCNEQQQEPAKISSFTSLKVSQDLDV AVIVSSSNSAVALNLNLYFRQHPGHLLCERILEDLPIQGPKGVDEDDPVNSAYNMKLAKFSFQIDRSWKAQLSSLNETIKNSKLEVSCCA PWFQDILHLESPESGNHSTSVQSWAFIPQDIMHGQYNVLQKDHAKTSDPGRSWKIMHISEQEEPIELKCVSVTGFTALFTWEVERMGYTI TLWDLETQGMQCFSLGTKCIPVDSSGDQQLCFVLTENGLSLILFGLTQEEFLNRLMIHGSASTVDTLCHLNGWGRCSIPIHALEAGIENR QLDTVNFFLKSKENLFNPSSKSSVSDQFDHLSSHLYLRTSSDNKKQIPNEASARSERDTSDLEQNWSLQDHYRMYSPIIYQALCEHVQTQ MSLMNDLTSKNIPNGIPAVPCHAPSHSESQATPHSSYGLCTSTPVWSLQRPPCPPKVHSEVQTDGNSQFASQGKTVSATCTDVLRNSFNT SPGVPCSLPKTDISAIPTLQQLGLVNGILPQQGIHKETDLLKCIQTYLSLFRSHGKETHLDSQTHRSPTQSQPAFLATNEEKCAREQIRE ATSERKDLNIHVRDTKTVKDVQKAKNVNKTAEKVRIIKYLLGELKALVAEQEDSEIQRLITEMEACISVLPTVSGNTDIQVEIALAMQPL RSENAQLRRQLRILNQQLREQQKTQKPSGAVDCNLELFSLQSLNMSLQNQLEESLKSQELLQSKNEELLKVIENQKDENKKFSSIFKDKD QTILENKQQYDIEITRIKIELEEALVNVKSSQFKLETAEKENQILGITLRQRDAEVTRLRELTRTLQTSMAKLLSDLSVDSARCKPGNNL TKSLLNIHDKQLQHDPAPAHTSIMSYLNKLETNYSFTHSEPLSTIKNEETIEPDKTYENVLSSRGPQNSNTRGMEEASAPGIISALSKQD SDEGSETMALIEDEHNLDNTIYIPFARSTPEKKSPLSKRLSPQPQIRAATTQLVSNSGLAVSGKENKLCTPVICSSSTKEAEDAPEKLSR ASDMKDTQLLKKIKEAIGKIPAATKEPEEQTACHGPSGCLSNSLQVKGNTVCDGSVFTSDLMSDWSISSFSTFTSRDEQDFRNGLAALDA -------------------------------------------------------------- >85734_85734_4_SPG11-CCDC14_SPG11_chr15_44925703_ENST00000427534_CCDC14_chr3_123667979_ENST00000488653_length(transcript)=5427nt_BP=1735nt ATGGCTGCAGAGGAAGGGGTCGCGAGTGCTGCTTCCGCCGGCGGTAGCTGGGGCACCGCGGCCATGGGGCGGGTTCTACCGATGCTGTTG GTGCCAGTCCCCGCCGAGGCGATGGGGCAGCTCGGCTCCCGGGCGCAGCTGCGCACACAGCCGGAGGCTCTGGGGAGCCTGACGGCTGCG GGCAGCCTCCAAGTGCTTTCTTTGACGCCTGGCAGCCGGGGCGGGGGTCGCTGCTGCCTGGAGGGCCCCTTCTGGCACTTTCTATGGGAG GATTCTCGTAACAGCAGCACACCAACTGAAAAGCCCAAACTGCTCGCTCTTGGTGAAAATTATGAACTGCTTATCTATGAATTTAATTTG AAAGATGGAAGATGTGATGCAACCATTTTGTATAGCTGTAGTAGGGAGGCATTGCAAAAGCTCATTGACGATCAAGATATCAGTATTTCC TTATTGTCTTTGAGAATCCTGTCATTTCACAATAACACATCATTACTGTTCATCAACAAATGTGTCATCCTACATATTATATTTCCTGAA AGAGATGCTGCAATTAGAGTACTCAACTGTTTCACACTTCCCTTGCCTGCACAGGCAGTGGACATGATTATTGACACGCAGCTCTGCAGA GGAATTCTTTTTGTTTTGAGTAGTTTAGGCTGGATCTACATTTTTGATGTTGTGGATGGTACATATGTAGCTCATGTGGATTTAGCACTT CACAAAGAAGACATGTGTAATGAGCAGCAACAGGAGCCAGCCAAGATTTCTTCATTTACTTCACTGAAAGTTTCTCAAGACCTCGATGTT GCAGTGATTGTCAGCTCCTCCAACTCCGCAGTTGCTCTTAACTTAAATTTGTATTTCAGGCAACACCCAGGACACCTACTGTGTGAAAGA ATACTAGAAGATCTTCCTATTCAAGGACCTAAGGGCGTAGATGAAGATGATCCTGTTAACTCTGCCTACAACATGAAACTGGCCAAGTTT TCCTTCCAAATTGATAGGTCTTGGAAAGCCCAGCTATCATCATTGAATGAAACAATAAAGAACTCCAAACTGGAGGTTTCCTGTTGTGCT CCATGGTTCCAGGATATTTTGCATTTGGAGTCACCTGAATCTGGTAACCACAGTACAAGTGTGCAGAGCTGGGCCTTCATTCCACAGGAC ATAATGCATGGGCAATATAATGTTCTACAGAAAGATCATGCCAAGACCAGTGATCCAGGAAGATCATGGAAAATAATGCACATCAGTGAA CAAGAGGAACCCATAGAGCTTAAATGTGTGTCTGTGACAGGATTCACTGCACTGTTTACTTGGGAAGTGGAAAGGATGGGCTATACCATT ACCCTCTGGGATTTGGAGACCCAGGGCATGCAGTGTTTTTCCCTTGGCACAAAGTGTATTCCTGTAGACAGTAGTGGAGACCAGCAGCTG TGCTTTGTTTTGACAGAGAATGGACTCTCTCTGATTTTGTTTGGTTTGACTCAAGAAGAGTTTTTAAACAGACTCATGATCCATGGAAGT GCCAGCACTGTGGACACTCTTTGTCATCTCAATGGCTGGGGAAGGTGCTCAATTCCCATACATGCACTAGAGGCCGGGATAGAAAATCGT CAGCTGGACACAGTAAATTTCTTTTTGAAGAGCAAGGAAAATCTTTTTAATCCATCCTCAAAATCTTCTGTATCTGATCAGTTTGATCAC TTGTCATCCCATTTATATTTAAGAACATCTTCAGATAATAAGAAACAGATACCTAATGAAGCTTCTGCTAGAAGTGAAAGAGACACATCA GACCTAGAGCAAAACTGGTCATTGCAAGATCATTATAGAATGTATTCACCCATAATATACCAAGCCCTCTGTGAGCACGTGCAGACTCAG ATGTCACTGATGAATGACTTGACTTCAAAGAACATCCCTAATGGAATTCCTGCTGTACCATGCCATGCTCCCTCTCATTCTGAATCTCAG GCAACTCCTCATTCTAGTTATGGCTTATGTACCTCCACCCCAGTCTGGTCACTTCAGCGGCCACCCTGCCCTCCAAAGGTTCATTCTGAA GTTCAAACTGATGGCAACAGTCAGTTTGCATCACAAGGTAAAACAGTTTCTGCAACCTGTACTGATGTTCTACGGAATTCATTTAATACC AGTCCTGGAGTTCCATGTAGCCTGCCCAAAACTGACATATCAGCTATTCCAACATTGCAGCAACTGGGCCTTGTTAATGGAATTCTGCCA CAACAAGGAATTCATAAGGAAACAGACCTACTAAAATGTATTCAAACATATTTGTCTCTTTTTCGATCTCATGGAAAAGAAACGCATCTG GACAGTCAGACACACCGAAGCCCTACTCAGTCACAACCAGCTTTCTTGGCCACTAATGAAGAAAAATGTGCCAGAGAGCAAATTAGAGAG GCCACAAGTGAAAGAAAGGATTTAAACATACATGTGCGAGATACAAAAACAGTGAAGGATGTACAGAAGGCAAAAAATGTGAACAAGACA GCTGAAAAAGTTAGAATTATAAAATATTTGTTGGGAGAGCTCAAGGCCCTGGTAGCAGAACAAGAGGATTCAGAAATTCAGAGGTTGATT ACAGAAATGGAGGCATGTATATCTGTACTTCCAACAGTAAGTGGAAACACAGATATTCAAGTTGAGATAGCACTGGCCATGCAACCATTA AGAAGTGAGAATGCTCAGTTACGAAGGCAGTTGAGAATTTTGAACCAGCAACTCAGAGAACAACAGAAAACTCAAAAACCATCTGGTGCT GTGGATTGCAACCTTGAATTGTTTTCTCTTCAGTCATTGAATATGTCACTGCAAAATCAATTGGAGGAGTCACTAAAGAGCCAGGAATTA CTGCAGAGTAAAAATGAAGAGCTGTTAAAAGTGATTGAAAATCAGAAAGATGAAAACAAAAAATTTAGTAGTATATTTAAAGACAAAGAT CAAACTATACTTGAAAATAAACAGCAATATGATATTGAGATAACAAGAATAAAAATTGAATTGGAGGAAGCCCTAGTCAATGTGAAAAGC TCCCAGTTTAAGTTAGAAACTGCTGAAAAGGAAAACCAGATATTGGGGATAACATTACGTCAGCGTGATGCTGAGGTGACTCGACTAAGA GAATTAACCAGAACTTTACAGACTAGCATGGCAAAGCTTCTCTCCGATCTTAGTGTGGACAGTGCTCGCTGCAAGCCTGGGAATAACCTT ACCAAATCACTCTTGAACATTCATGATAAACAACTTCAACATGACCCAGCTCCTGCTCACACTTCCATAATGAGCTATCTAAATAAGTTA GAAACAAATTACAGTTTTACACATTCAGAGCCACTTTCTACAATTAAAAATGAGGAAACCATAGAGCCAGACAAAACCTATGAAAATGTT CTGTCCTCCAGAGGCCCTCAAAATAGTAACACTAGGGGCATGGAGGAAGCATCTGCACCTGGAATTATTTCTGCCCTTTCAAAACAGGAT TCTGATGAAGGGAGTGAAACTATGGCTTTAATAGAAGATGAGCATAATTTGGATAATACAATTTACATTCCTTTTGCTAGAAGCACTCCT GAAAAGAAATCACCACTTTCTAAGAGACTATCCCCTCAGCCACAAATAAGAGCAGCTACAACACAGCTAGTCAGCAACAGCGGACTTGCT GTCTCTGGAAAAGAAAATAAACTGTGTACACCTGTAATCTGTTCCTCTTCAACAAAGGAAGCAGAAGATGCACCTGAAAAACTTTCCAGA GCATCTGATATGAAGGACACACAGCTCCTCAAGAAAATAAAGGAAGCAATTGGTAAGATCCCTGCTGCCACCAAGGAGCCAGAGGAACAA ACTGCATGTCATGGCCCATCAGGTTGTCTTAGCAACAGCCTTCAAGTGAAAGGCAATACTGTCTGTGATGGTAGTGTTTTCACTTCTGAC TTGATGTCTGACTGGAGCATCTCTTCGTTTTCAACGTTCACTTCTCGTGATGAACAAGACTTCAGAAATGGCCTTGCGGCATTAGATGCC AACATAGCTAGACTCCAGAAGTCTTTAAGGACTGGTCTTCTGGAGAAATGAATTCAGAAGAAAACTCATCAGGTGCTTCTTTTTAAAACT AGAACTTGGCTATATTGAATGTGTATTTTTCTTTAGTGAAATGATGTTTTATGTTATTATGTGTGAAGTAATATATTGTACAAGTAATAA ATGTATTGTTGAGATATATTGACACTGAGGAGCTTATAAAAACAAGTCATCTTAAGTTCACAATTGCTACAAGAAGAAAGTTGTGGATAA CTAGGAAATTATTGTAAGTAATGTTTTATTTCAGTACTTAGCAATTAGAGTTCTTTTATTAAGATGTATCTGCTGGATTAAGGGTACAGG TTGAAATAGTTCTGTGGCTGTCCTAAGAAATAATGGGAAAAGAATCTCTGGATGTAAGTTTTTCTGTTGAAACTAGAGGGTTTTTTTTTT CTGTTTACATATACTTTTTTTTAATAGCAATGTGTTTTTATTAAACATGCTGTGTGCCACAGGCCAGTGTTGTTGGTGAAATATATAAAC ATTTATTTAAAGAGAAAAGTTACCAGTATCTACACCTCTTAAAAAACATTGATTGGTCTAAAAAATATATAGATAACATCCTAAGTTAAC ATATGGCTTCTTAAAACTTGGGCACTTTTATTTGTTTTTATCCCAAATTCATGTTTTAAGGCCTTTAAAGAATAGTCAGACTGATAAAGA AGTGCTAACAGATAAGCTATAGTTGGGGAAATTTGTGGGTTTTTTTTAAATAAGAAATGTTTATTTTTGTCCTTATATTTAAACATGATG GAATTTGTAAATCTTGGCATTGATTGTAATTCTGCCTTTTTGGAAGAATTTTTTCTCCCAGCATGTTAGCTGAGAATATTCTCTATTTTA TAAATAATATGAAGTAGGTTGGTCTCTCTGCTTCTCTATACCAGGACTTCTTAGCTCAGTATCATCTCCCTTCATGTAAGCAGCACGTTT TAACTCTTAGGAAGCTGAATGTTGTGTTATCACTAATACTTTGTACAGGTCACCTGCCTACTCTAATTGTCCTTAGTACTTGGACAGGCT TTATCATTAAAGAGTGTTCTCCTAATCCCAGAACCTCCTCGTGTTTTTTGTTTTTTTGGTGGTTTTTTTTTTTTTTTTAGGTGTTAGTGC TACAGCGTTTGAAGGAGCCAGCTGTAGTCTCTTTGATATGTTCAGATTTTCCAGATAGAGATTTAAGTCTAAAAATTTATTAAGTGAATT CTAAACTATTTCACACAAGAGTCCATTAGCATCTTTAATTTTATTTAGTATTCATGAATTAATTTATTGGCATCTTATTTGGAGGTAATA >85734_85734_4_SPG11-CCDC14_SPG11_chr15_44925703_ENST00000427534_CCDC14_chr3_123667979_ENST00000488653_length(amino acids)=1366AA_BP=579 MAAEEGVASAASAGGSWGTAAMGRVLPMLLVPVPAEAMGQLGSRAQLRTQPEALGSLTAAGSLQVLSLTPGSRGGGRCCLEGPFWHFLWE DSRNSSTPTEKPKLLALGENYELLIYEFNLKDGRCDATILYSCSREALQKLIDDQDISISLLSLRILSFHNNTSLLFINKCVILHIIFPE RDAAIRVLNCFTLPLPAQAVDMIIDTQLCRGILFVLSSLGWIYIFDVVDGTYVAHVDLALHKEDMCNEQQQEPAKISSFTSLKVSQDLDV AVIVSSSNSAVALNLNLYFRQHPGHLLCERILEDLPIQGPKGVDEDDPVNSAYNMKLAKFSFQIDRSWKAQLSSLNETIKNSKLEVSCCA PWFQDILHLESPESGNHSTSVQSWAFIPQDIMHGQYNVLQKDHAKTSDPGRSWKIMHISEQEEPIELKCVSVTGFTALFTWEVERMGYTI TLWDLETQGMQCFSLGTKCIPVDSSGDQQLCFVLTENGLSLILFGLTQEEFLNRLMIHGSASTVDTLCHLNGWGRCSIPIHALEAGIENR QLDTVNFFLKSKENLFNPSSKSSVSDQFDHLSSHLYLRTSSDNKKQIPNEASARSERDTSDLEQNWSLQDHYRMYSPIIYQALCEHVQTQ MSLMNDLTSKNIPNGIPAVPCHAPSHSESQATPHSSYGLCTSTPVWSLQRPPCPPKVHSEVQTDGNSQFASQGKTVSATCTDVLRNSFNT SPGVPCSLPKTDISAIPTLQQLGLVNGILPQQGIHKETDLLKCIQTYLSLFRSHGKETHLDSQTHRSPTQSQPAFLATNEEKCAREQIRE ATSERKDLNIHVRDTKTVKDVQKAKNVNKTAEKVRIIKYLLGELKALVAEQEDSEIQRLITEMEACISVLPTVSGNTDIQVEIALAMQPL RSENAQLRRQLRILNQQLREQQKTQKPSGAVDCNLELFSLQSLNMSLQNQLEESLKSQELLQSKNEELLKVIENQKDENKKFSSIFKDKD QTILENKQQYDIEITRIKIELEEALVNVKSSQFKLETAEKENQILGITLRQRDAEVTRLRELTRTLQTSMAKLLSDLSVDSARCKPGNNL TKSLLNIHDKQLQHDPAPAHTSIMSYLNKLETNYSFTHSEPLSTIKNEETIEPDKTYENVLSSRGPQNSNTRGMEEASAPGIISALSKQD SDEGSETMALIEDEHNLDNTIYIPFARSTPEKKSPLSKRLSPQPQIRAATTQLVSNSGLAVSGKENKLCTPVICSSSTKEAEDAPEKLSR ASDMKDTQLLKKIKEAIGKIPAATKEPEEQTACHGPSGCLSNSLQVKGNTVCDGSVFTSDLMSDWSISSFSTFTSRDEQDFRNGLAALDA -------------------------------------------------------------- >85734_85734_5_SPG11-CCDC14_SPG11_chr15_44925703_ENST00000535302_CCDC14_chr3_123667979_ENST00000310351_length(transcript)=5455nt_BP=1763nt AGTGACCGGAAGTAACCGCCGGGCCAAGATGGCTGCAGAGGAAGGGGTCGCGAGTGCTGCTTCCGCCGGCGGTAGCTGGGGCACCGCGGC CATGGGGCGGGTTCTACCGATGCTGTTGGTGCCAGTCCCCGCCGAGGCGATGGGGCAGCTCGGCTCCCGGGCGCAGCTGCGCACACAGCC GGAGGCTCTGGGGAGCCTGACGGCTGCGGGCAGCCTCCAAGTGCTTTCTTTGACGCCTGGCAGCCGGGGCGGGGGTCGCTGCTGCCTGGA GGGCCCCTTCTGGCACTTTCTATGGGAGGATTCTCGTAACAGCAGCACACCAACTGAAAAGCCCAAACTGCTCGCTCTTGGTGAAAATTA TGAACTGCTTATCTATGAATTTAATTTGAAAGATGGAAGATGTGATGCAACCATTTTGTATAGCTGTAGTAGGGAGGCATTGCAAAAGCT CATTGACGATCAAGATATCAGTATTTCCTTATTGTCTTTGAGAATCCTGTCATTTCACAATAACACATCATTACTGTTCATCAACAAATG TGTCATCCTACATATTATATTTCCTGAAAGAGATGCTGCAATTAGAGTACTCAACTGTTTCACACTTCCCTTGCCTGCACAGGCAGTGGA CATGATTATTGACACGCAGCTCTGCAGAGGAATTCTTTTTGTTTTGAGTAGTTTAGGCTGGATCTACATTTTTGATGTTGTGGATGGTAC ATATGTAGCTCATGTGGATTTAGCACTTCACAAAGAAGACATGTGTAATGAGCAGCAACAGGAGCCAGCCAAGATTTCTTCATTTACTTC ACTGAAAGTTTCTCAAGACCTCGATGTTGCAGTGATTGTCAGCTCCTCCAACTCCGCAGTTGCTCTTAACTTAAATTTGTATTTCAGGCA ACACCCAGGACACCTACTGTGTGAAAGAATACTAGAAGATCTTCCTATTCAAGGACCTAAGGGCGTAGATGAAGATGATCCTGTTAACTC TGCCTACAACATGAAACTGGCCAAGTTTTCCTTCCAAATTGATAGGTCTTGGAAAGCCCAGCTATCATCATTGAATGAAACAATAAAGAA CTCCAAACTGGAGGTTTCCTGTTGTGCTCCATGGTTCCAGGATATTTTGCATTTGGAGTCACCTGAATCTGGTAACCACAGTACAAGTGT GCAGAGCTGGGCCTTCATTCCACAGGACATAATGCATGGGCAATATAATGTTCTACAGAAAGATCATGCCAAGACCAGTGATCCAGGAAG ATCATGGAAAATAATGCACATCAGTGAACAAGAGGAACCCATAGAGCTTAAATGTGTGTCTGTGACAGGATTCACTGCACTGTTTACTTG GGAAGTGGAAAGGATGGGCTATACCATTACCCTCTGGGATTTGGAGACCCAGGGCATGCAGTGTTTTTCCCTTGGCACAAAGTGTATTCC TGTAGACAGTAGTGGAGACCAGCAGCTGTGCTTTGTTTTGACAGAGAATGGACTCTCTCTGATTTTGTTTGGTTTGACTCAAGAAGAGTT TTTAAACAGACTCATGATCCATGGAAGTGCCAGCACTGTGGACACTCTTTGTCATCTCAATGGCTGGGGAAGGTGCTCAATTCCCATACA TGCACTAGAGGCCGGGATAGAAAATCGTCAGCTGGACACAGTAAATTTCTTTTTGAAGAGCAAGGAAAATCTTTTTAATCCATCCTCAAA ATCTTCTGTATCTGATCAGTTTGATCACTTGTCATCCCATTTATATTTAAGAACATCTTCAGATAATAAGAAACAGATACCTAATGAAGC TTCTGCTAGAAGTGAAAGAGACACATCAGACCTAGAGCAAAACTGGTCATTGCAAGATCATTATAGAATGTATTCACCCATAATATACCA AGCCCTCTGTGAGCACGTGCAGACTCAGATGTCACTGATGAATGACTTGACTTCAAAGAACATCCCTAATGGAATTCCTGCTGTACCATG CCATGCTCCCTCTCATTCTGAATCTCAGGCAACTCCTCATTCTAGTTATGGCTTATGTACCTCCACCCCAGTCTGGTCACTTCAGCGGCC ACCCTGCCCTCCAAAGGTTCATTCTGAAGTTCAAACTGATGGCAACAGTCAGTTTGCATCACAAGGTAAAACAGTTTCTGCAACCTGTAC TGATGTTCTACGGAATTCATTTAATACCAGTCCTGGAGTTCCATGTAGCCTGCCCAAAACTGACATATCAGCTATTCCAACATTGCAGCA ACTGGGCCTTGTTAATGGAATTCTGCCACAACAAGGAATTCATAAGGAAACAGACCTACTAAAATGTATTCAAACATATTTGTCTCTTTT TCGATCTCATGGAAAAGAAACGCATCTGGACAGTCAGACACACCGAAGCCCTACTCAGTCACAACCAGCTTTCTTGGCCACTAATGAAGA AAAATGTGCCAGAGAGCAAATTAGAGAGGCCACAAGTGAAAGAAAGGATTTAAACATACATGTGCGAGATACAAAAACAGTGAAGGATGT ACAGAAGGCAAAAAATGTGAACAAGACAGCTGAAAAAGTTAGAATTATAAAATATTTGTTGGGAGAGCTCAAGGCCCTGGTAGCAGAACA AGAGGATTCAGAAATTCAGAGGTTGATTACAGAAATGGAGGCATGTATATCTGTACTTCCAACAGTAAGTGGAAACACAGATATTCAAGT TGAGATAGCACTGGCCATGCAACCATTAAGAAGTGAGAATGCTCAGTTACGAAGGCAGTTGAGAATTTTGAACCAGCAACTCAGAGAACA ACAGAAAACTCAAAAACCATCTGGTGCTGTGGATTGCAACCTTGAATTGTTTTCTCTTCAGTCATTGAATATGTCACTGCAAAATCAATT GGAGGAGTCACTAAAGAGCCAGGAATTACTGCAGAGTAAAAATGAAGAGCTGTTAAAAGTGATTGAAAATCAGAAAGATGAAAACAAAAA ATTTAGTAGTATATTTAAAGACAAAGATCAAACTATACTTGAAAATAAACAGCAATATGATATTGAGATAACAAGAATAAAAATTGAATT GGAGGAAGCCCTAGTCAATGTGAAAAGCTCCCAGTTTAAGTTAGAAACTGCTGAAAAGGAAAACCAGATATTGGGGATAACATTACGTCA GCGTGATGCTGAGGTGACTCGACTAAGAGAATTAACCAGAACTTTACAGACTAGCATGGCAAAGCTTCTCTCCGATCTTAGTGTGGACAG TGCTCGCTGCAAGCCTGGGAATAACCTTACCAAATCACTCTTGAACATTCATGATAAACAACTTCAACATGACCCAGCTCCTGCTCACAC TTCCATAATGAGCTATCTAAATAAGTTAGAAACAAATTACAGTTTTACACATTCAGAGCCACTTTCTACAATTAAAAATGAGGAAACCAT AGAGCCAGACAAAACCTATGAAAATGTTCTGTCCTCCAGAGGCCCTCAAAATAGTAACACTAGGGGCATGGAGGAAGCATCTGCACCTGG AATTATTTCTGCCCTTTCAAAACAGGATTCTGATGAAGGGAGTGAAACTATGGCTTTAATAGAAGATGAGCATAATTTGGATAATACAAT TTACATTCCTTTTGCTAGAAGCACTCCTGAAAAGAAATCACCACTTTCTAAGAGACTATCCCCTCAGCCACAAATAAGAGCAGCTACAAC ACAGCTAGTCAGCAACAGCGGACTTGCTGTCTCTGGAAAAGAAAATAAACTGTGTACACCTGTAATCTGTTCCTCTTCAACAAAGGAAGC AGAAGATGCACCTGAAAAACTTTCCAGAGCATCTGATATGAAGGACACACAGCTCCTCAAGAAAATAAAGGAAGCAATTGGTAAGATCCC TGCTGCCACCAAGGAGCCAGAGGAACAAACTGCATGTCATGGCCCATCAGGTTGTCTTAGCAACAGCCTTCAAGTGAAAGGCAATACTGT CTGTGATGGTAGTGTTTTCACTTCTGACTTGATGTCTGACTGGAGCATCTCTTCGTTTTCAACGTTCACTTCTCGTGATGAACAAGACTT CAGAAATGGCCTTGCGGCATTAGATGCCAACATAGCTAGACTCCAGAAGTCTTTAAGGACTGGTCTTCTGGAGAAATGAATTCAGAAGAA AACTCATCAGGTGCTTCTTTTTAAAACTAGAACTTGGCTATATTGAATGTGTATTTTTCTTTAGTGAAATGATGTTTTATGTTATTATGT GTGAAGTAATATATTGTACAAGTAATAAATGTATTGTTGAGATATATTGACACTGAGGAGCTTATAAAAACAAGTCATCTTAAGTTCACA ATTGCTACAAGAAGAAAGTTGTGGATAACTAGGAAATTATTGTAAGTAATGTTTTATTTCAGTACTTAGCAATTAGAGTTCTTTTATTAA GATGTATCTGCTGGATTAAGGGTACAGGTTGAAATAGTTCTGTGGCTGTCCTAAGAAATAATGGGAAAAGAATCTCTGGATGTAAGTTTT TCTGTTGAAACTAGAGGGTTTTTTTTTTCTGTTTACATATACTTTTTTTTAATAGCAATGTGTTTTTATTAAACATGCTGTGTGCCACAG GCCAGTGTTGTTGGTGAAATATATAAACATTTATTTAAAGAGAAAAGTTACCAGTATCTACACCTCTTAAAAAACATTGATTGGTCTAAA AAATATATAGATAACATCCTAAGTTAACATATGGCTTCTTAAAACTTGGGCACTTTTATTTGTTTTTATCCCAAATTCATGTTTTAAGGC CTTTAAAGAATAGTCAGACTGATAAAGAAGTGCTAACAGATAAGCTATAGTTGGGGAAATTTGTGGGTTTTTTTTAAATAAGAAATGTTT ATTTTTGTCCTTATATTTAAACATGATGGAATTTGTAAATCTTGGCATTGATTGTAATTCTGCCTTTTTGGAAGAATTTTTTCTCCCAGC ATGTTAGCTGAGAATATTCTCTATTTTATAAATAATATGAAGTAGGTTGGTCTCTCTGCTTCTCTATACCAGGACTTCTTAGCTCAGTAT CATCTCCCTTCATGTAAGCAGCACGTTTTAACTCTTAGGAAGCTGAATGTTGTGTTATCACTAATACTTTGTACAGGTCACCTGCCTACT CTAATTGTCCTTAGTACTTGGACAGGCTTTATCATTAAAGAGTGTTCTCCTAATCCCAGAACCTCCTCGTGTTTTTTGTTTTTTTGGTGG TTTTTTTTTTTTTTTTAGGTGTTAGTGCTACAGCGTTTGAAGGAGCCAGCTGTAGTCTCTTTGATATGTTCAGATTTTCCAGATAGAGAT TTAAGTCTAAAAATTTATTAAGTGAATTCTAAACTATTTCACACAAGAGTCCATTAGCATCTTTAATTTTATTTAGTATTCATGAATTAA >85734_85734_5_SPG11-CCDC14_SPG11_chr15_44925703_ENST00000535302_CCDC14_chr3_123667979_ENST00000310351_length(amino acids)=1366AA_BP=579 MAAEEGVASAASAGGSWGTAAMGRVLPMLLVPVPAEAMGQLGSRAQLRTQPEALGSLTAAGSLQVLSLTPGSRGGGRCCLEGPFWHFLWE DSRNSSTPTEKPKLLALGENYELLIYEFNLKDGRCDATILYSCSREALQKLIDDQDISISLLSLRILSFHNNTSLLFINKCVILHIIFPE RDAAIRVLNCFTLPLPAQAVDMIIDTQLCRGILFVLSSLGWIYIFDVVDGTYVAHVDLALHKEDMCNEQQQEPAKISSFTSLKVSQDLDV AVIVSSSNSAVALNLNLYFRQHPGHLLCERILEDLPIQGPKGVDEDDPVNSAYNMKLAKFSFQIDRSWKAQLSSLNETIKNSKLEVSCCA PWFQDILHLESPESGNHSTSVQSWAFIPQDIMHGQYNVLQKDHAKTSDPGRSWKIMHISEQEEPIELKCVSVTGFTALFTWEVERMGYTI TLWDLETQGMQCFSLGTKCIPVDSSGDQQLCFVLTENGLSLILFGLTQEEFLNRLMIHGSASTVDTLCHLNGWGRCSIPIHALEAGIENR QLDTVNFFLKSKENLFNPSSKSSVSDQFDHLSSHLYLRTSSDNKKQIPNEASARSERDTSDLEQNWSLQDHYRMYSPIIYQALCEHVQTQ MSLMNDLTSKNIPNGIPAVPCHAPSHSESQATPHSSYGLCTSTPVWSLQRPPCPPKVHSEVQTDGNSQFASQGKTVSATCTDVLRNSFNT SPGVPCSLPKTDISAIPTLQQLGLVNGILPQQGIHKETDLLKCIQTYLSLFRSHGKETHLDSQTHRSPTQSQPAFLATNEEKCAREQIRE ATSERKDLNIHVRDTKTVKDVQKAKNVNKTAEKVRIIKYLLGELKALVAEQEDSEIQRLITEMEACISVLPTVSGNTDIQVEIALAMQPL RSENAQLRRQLRILNQQLREQQKTQKPSGAVDCNLELFSLQSLNMSLQNQLEESLKSQELLQSKNEELLKVIENQKDENKKFSSIFKDKD QTILENKQQYDIEITRIKIELEEALVNVKSSQFKLETAEKENQILGITLRQRDAEVTRLRELTRTLQTSMAKLLSDLSVDSARCKPGNNL TKSLLNIHDKQLQHDPAPAHTSIMSYLNKLETNYSFTHSEPLSTIKNEETIEPDKTYENVLSSRGPQNSNTRGMEEASAPGIISALSKQD SDEGSETMALIEDEHNLDNTIYIPFARSTPEKKSPLSKRLSPQPQIRAATTQLVSNSGLAVSGKENKLCTPVICSSSTKEAEDAPEKLSR ASDMKDTQLLKKIKEAIGKIPAATKEPEEQTACHGPSGCLSNSLQVKGNTVCDGSVFTSDLMSDWSISSFSTFTSRDEQDFRNGLAALDA -------------------------------------------------------------- >85734_85734_6_SPG11-CCDC14_SPG11_chr15_44925703_ENST00000535302_CCDC14_chr3_123667979_ENST00000488653_length(transcript)=5455nt_BP=1763nt AGTGACCGGAAGTAACCGCCGGGCCAAGATGGCTGCAGAGGAAGGGGTCGCGAGTGCTGCTTCCGCCGGCGGTAGCTGGGGCACCGCGGC CATGGGGCGGGTTCTACCGATGCTGTTGGTGCCAGTCCCCGCCGAGGCGATGGGGCAGCTCGGCTCCCGGGCGCAGCTGCGCACACAGCC GGAGGCTCTGGGGAGCCTGACGGCTGCGGGCAGCCTCCAAGTGCTTTCTTTGACGCCTGGCAGCCGGGGCGGGGGTCGCTGCTGCCTGGA GGGCCCCTTCTGGCACTTTCTATGGGAGGATTCTCGTAACAGCAGCACACCAACTGAAAAGCCCAAACTGCTCGCTCTTGGTGAAAATTA TGAACTGCTTATCTATGAATTTAATTTGAAAGATGGAAGATGTGATGCAACCATTTTGTATAGCTGTAGTAGGGAGGCATTGCAAAAGCT CATTGACGATCAAGATATCAGTATTTCCTTATTGTCTTTGAGAATCCTGTCATTTCACAATAACACATCATTACTGTTCATCAACAAATG TGTCATCCTACATATTATATTTCCTGAAAGAGATGCTGCAATTAGAGTACTCAACTGTTTCACACTTCCCTTGCCTGCACAGGCAGTGGA CATGATTATTGACACGCAGCTCTGCAGAGGAATTCTTTTTGTTTTGAGTAGTTTAGGCTGGATCTACATTTTTGATGTTGTGGATGGTAC ATATGTAGCTCATGTGGATTTAGCACTTCACAAAGAAGACATGTGTAATGAGCAGCAACAGGAGCCAGCCAAGATTTCTTCATTTACTTC ACTGAAAGTTTCTCAAGACCTCGATGTTGCAGTGATTGTCAGCTCCTCCAACTCCGCAGTTGCTCTTAACTTAAATTTGTATTTCAGGCA ACACCCAGGACACCTACTGTGTGAAAGAATACTAGAAGATCTTCCTATTCAAGGACCTAAGGGCGTAGATGAAGATGATCCTGTTAACTC TGCCTACAACATGAAACTGGCCAAGTTTTCCTTCCAAATTGATAGGTCTTGGAAAGCCCAGCTATCATCATTGAATGAAACAATAAAGAA CTCCAAACTGGAGGTTTCCTGTTGTGCTCCATGGTTCCAGGATATTTTGCATTTGGAGTCACCTGAATCTGGTAACCACAGTACAAGTGT GCAGAGCTGGGCCTTCATTCCACAGGACATAATGCATGGGCAATATAATGTTCTACAGAAAGATCATGCCAAGACCAGTGATCCAGGAAG ATCATGGAAAATAATGCACATCAGTGAACAAGAGGAACCCATAGAGCTTAAATGTGTGTCTGTGACAGGATTCACTGCACTGTTTACTTG GGAAGTGGAAAGGATGGGCTATACCATTACCCTCTGGGATTTGGAGACCCAGGGCATGCAGTGTTTTTCCCTTGGCACAAAGTGTATTCC TGTAGACAGTAGTGGAGACCAGCAGCTGTGCTTTGTTTTGACAGAGAATGGACTCTCTCTGATTTTGTTTGGTTTGACTCAAGAAGAGTT TTTAAACAGACTCATGATCCATGGAAGTGCCAGCACTGTGGACACTCTTTGTCATCTCAATGGCTGGGGAAGGTGCTCAATTCCCATACA TGCACTAGAGGCCGGGATAGAAAATCGTCAGCTGGACACAGTAAATTTCTTTTTGAAGAGCAAGGAAAATCTTTTTAATCCATCCTCAAA ATCTTCTGTATCTGATCAGTTTGATCACTTGTCATCCCATTTATATTTAAGAACATCTTCAGATAATAAGAAACAGATACCTAATGAAGC TTCTGCTAGAAGTGAAAGAGACACATCAGACCTAGAGCAAAACTGGTCATTGCAAGATCATTATAGAATGTATTCACCCATAATATACCA AGCCCTCTGTGAGCACGTGCAGACTCAGATGTCACTGATGAATGACTTGACTTCAAAGAACATCCCTAATGGAATTCCTGCTGTACCATG CCATGCTCCCTCTCATTCTGAATCTCAGGCAACTCCTCATTCTAGTTATGGCTTATGTACCTCCACCCCAGTCTGGTCACTTCAGCGGCC ACCCTGCCCTCCAAAGGTTCATTCTGAAGTTCAAACTGATGGCAACAGTCAGTTTGCATCACAAGGTAAAACAGTTTCTGCAACCTGTAC TGATGTTCTACGGAATTCATTTAATACCAGTCCTGGAGTTCCATGTAGCCTGCCCAAAACTGACATATCAGCTATTCCAACATTGCAGCA ACTGGGCCTTGTTAATGGAATTCTGCCACAACAAGGAATTCATAAGGAAACAGACCTACTAAAATGTATTCAAACATATTTGTCTCTTTT TCGATCTCATGGAAAAGAAACGCATCTGGACAGTCAGACACACCGAAGCCCTACTCAGTCACAACCAGCTTTCTTGGCCACTAATGAAGA AAAATGTGCCAGAGAGCAAATTAGAGAGGCCACAAGTGAAAGAAAGGATTTAAACATACATGTGCGAGATACAAAAACAGTGAAGGATGT ACAGAAGGCAAAAAATGTGAACAAGACAGCTGAAAAAGTTAGAATTATAAAATATTTGTTGGGAGAGCTCAAGGCCCTGGTAGCAGAACA AGAGGATTCAGAAATTCAGAGGTTGATTACAGAAATGGAGGCATGTATATCTGTACTTCCAACAGTAAGTGGAAACACAGATATTCAAGT TGAGATAGCACTGGCCATGCAACCATTAAGAAGTGAGAATGCTCAGTTACGAAGGCAGTTGAGAATTTTGAACCAGCAACTCAGAGAACA ACAGAAAACTCAAAAACCATCTGGTGCTGTGGATTGCAACCTTGAATTGTTTTCTCTTCAGTCATTGAATATGTCACTGCAAAATCAATT GGAGGAGTCACTAAAGAGCCAGGAATTACTGCAGAGTAAAAATGAAGAGCTGTTAAAAGTGATTGAAAATCAGAAAGATGAAAACAAAAA ATTTAGTAGTATATTTAAAGACAAAGATCAAACTATACTTGAAAATAAACAGCAATATGATATTGAGATAACAAGAATAAAAATTGAATT GGAGGAAGCCCTAGTCAATGTGAAAAGCTCCCAGTTTAAGTTAGAAACTGCTGAAAAGGAAAACCAGATATTGGGGATAACATTACGTCA GCGTGATGCTGAGGTGACTCGACTAAGAGAATTAACCAGAACTTTACAGACTAGCATGGCAAAGCTTCTCTCCGATCTTAGTGTGGACAG TGCTCGCTGCAAGCCTGGGAATAACCTTACCAAATCACTCTTGAACATTCATGATAAACAACTTCAACATGACCCAGCTCCTGCTCACAC TTCCATAATGAGCTATCTAAATAAGTTAGAAACAAATTACAGTTTTACACATTCAGAGCCACTTTCTACAATTAAAAATGAGGAAACCAT AGAGCCAGACAAAACCTATGAAAATGTTCTGTCCTCCAGAGGCCCTCAAAATAGTAACACTAGGGGCATGGAGGAAGCATCTGCACCTGG AATTATTTCTGCCCTTTCAAAACAGGATTCTGATGAAGGGAGTGAAACTATGGCTTTAATAGAAGATGAGCATAATTTGGATAATACAAT TTACATTCCTTTTGCTAGAAGCACTCCTGAAAAGAAATCACCACTTTCTAAGAGACTATCCCCTCAGCCACAAATAAGAGCAGCTACAAC ACAGCTAGTCAGCAACAGCGGACTTGCTGTCTCTGGAAAAGAAAATAAACTGTGTACACCTGTAATCTGTTCCTCTTCAACAAAGGAAGC AGAAGATGCACCTGAAAAACTTTCCAGAGCATCTGATATGAAGGACACACAGCTCCTCAAGAAAATAAAGGAAGCAATTGGTAAGATCCC TGCTGCCACCAAGGAGCCAGAGGAACAAACTGCATGTCATGGCCCATCAGGTTGTCTTAGCAACAGCCTTCAAGTGAAAGGCAATACTGT CTGTGATGGTAGTGTTTTCACTTCTGACTTGATGTCTGACTGGAGCATCTCTTCGTTTTCAACGTTCACTTCTCGTGATGAACAAGACTT CAGAAATGGCCTTGCGGCATTAGATGCCAACATAGCTAGACTCCAGAAGTCTTTAAGGACTGGTCTTCTGGAGAAATGAATTCAGAAGAA AACTCATCAGGTGCTTCTTTTTAAAACTAGAACTTGGCTATATTGAATGTGTATTTTTCTTTAGTGAAATGATGTTTTATGTTATTATGT GTGAAGTAATATATTGTACAAGTAATAAATGTATTGTTGAGATATATTGACACTGAGGAGCTTATAAAAACAAGTCATCTTAAGTTCACA ATTGCTACAAGAAGAAAGTTGTGGATAACTAGGAAATTATTGTAAGTAATGTTTTATTTCAGTACTTAGCAATTAGAGTTCTTTTATTAA GATGTATCTGCTGGATTAAGGGTACAGGTTGAAATAGTTCTGTGGCTGTCCTAAGAAATAATGGGAAAAGAATCTCTGGATGTAAGTTTT TCTGTTGAAACTAGAGGGTTTTTTTTTTCTGTTTACATATACTTTTTTTTAATAGCAATGTGTTTTTATTAAACATGCTGTGTGCCACAG GCCAGTGTTGTTGGTGAAATATATAAACATTTATTTAAAGAGAAAAGTTACCAGTATCTACACCTCTTAAAAAACATTGATTGGTCTAAA AAATATATAGATAACATCCTAAGTTAACATATGGCTTCTTAAAACTTGGGCACTTTTATTTGTTTTTATCCCAAATTCATGTTTTAAGGC CTTTAAAGAATAGTCAGACTGATAAAGAAGTGCTAACAGATAAGCTATAGTTGGGGAAATTTGTGGGTTTTTTTTAAATAAGAAATGTTT ATTTTTGTCCTTATATTTAAACATGATGGAATTTGTAAATCTTGGCATTGATTGTAATTCTGCCTTTTTGGAAGAATTTTTTCTCCCAGC ATGTTAGCTGAGAATATTCTCTATTTTATAAATAATATGAAGTAGGTTGGTCTCTCTGCTTCTCTATACCAGGACTTCTTAGCTCAGTAT CATCTCCCTTCATGTAAGCAGCACGTTTTAACTCTTAGGAAGCTGAATGTTGTGTTATCACTAATACTTTGTACAGGTCACCTGCCTACT CTAATTGTCCTTAGTACTTGGACAGGCTTTATCATTAAAGAGTGTTCTCCTAATCCCAGAACCTCCTCGTGTTTTTTGTTTTTTTGGTGG TTTTTTTTTTTTTTTTAGGTGTTAGTGCTACAGCGTTTGAAGGAGCCAGCTGTAGTCTCTTTGATATGTTCAGATTTTCCAGATAGAGAT TTAAGTCTAAAAATTTATTAAGTGAATTCTAAACTATTTCACACAAGAGTCCATTAGCATCTTTAATTTTATTTAGTATTCATGAATTAA >85734_85734_6_SPG11-CCDC14_SPG11_chr15_44925703_ENST00000535302_CCDC14_chr3_123667979_ENST00000488653_length(amino acids)=1366AA_BP=579 MAAEEGVASAASAGGSWGTAAMGRVLPMLLVPVPAEAMGQLGSRAQLRTQPEALGSLTAAGSLQVLSLTPGSRGGGRCCLEGPFWHFLWE DSRNSSTPTEKPKLLALGENYELLIYEFNLKDGRCDATILYSCSREALQKLIDDQDISISLLSLRILSFHNNTSLLFINKCVILHIIFPE RDAAIRVLNCFTLPLPAQAVDMIIDTQLCRGILFVLSSLGWIYIFDVVDGTYVAHVDLALHKEDMCNEQQQEPAKISSFTSLKVSQDLDV AVIVSSSNSAVALNLNLYFRQHPGHLLCERILEDLPIQGPKGVDEDDPVNSAYNMKLAKFSFQIDRSWKAQLSSLNETIKNSKLEVSCCA PWFQDILHLESPESGNHSTSVQSWAFIPQDIMHGQYNVLQKDHAKTSDPGRSWKIMHISEQEEPIELKCVSVTGFTALFTWEVERMGYTI TLWDLETQGMQCFSLGTKCIPVDSSGDQQLCFVLTENGLSLILFGLTQEEFLNRLMIHGSASTVDTLCHLNGWGRCSIPIHALEAGIENR QLDTVNFFLKSKENLFNPSSKSSVSDQFDHLSSHLYLRTSSDNKKQIPNEASARSERDTSDLEQNWSLQDHYRMYSPIIYQALCEHVQTQ MSLMNDLTSKNIPNGIPAVPCHAPSHSESQATPHSSYGLCTSTPVWSLQRPPCPPKVHSEVQTDGNSQFASQGKTVSATCTDVLRNSFNT SPGVPCSLPKTDISAIPTLQQLGLVNGILPQQGIHKETDLLKCIQTYLSLFRSHGKETHLDSQTHRSPTQSQPAFLATNEEKCAREQIRE ATSERKDLNIHVRDTKTVKDVQKAKNVNKTAEKVRIIKYLLGELKALVAEQEDSEIQRLITEMEACISVLPTVSGNTDIQVEIALAMQPL RSENAQLRRQLRILNQQLREQQKTQKPSGAVDCNLELFSLQSLNMSLQNQLEESLKSQELLQSKNEELLKVIENQKDENKKFSSIFKDKD QTILENKQQYDIEITRIKIELEEALVNVKSSQFKLETAEKENQILGITLRQRDAEVTRLRELTRTLQTSMAKLLSDLSVDSARCKPGNNL TKSLLNIHDKQLQHDPAPAHTSIMSYLNKLETNYSFTHSEPLSTIKNEETIEPDKTYENVLSSRGPQNSNTRGMEEASAPGIISALSKQD SDEGSETMALIEDEHNLDNTIYIPFARSTPEKKSPLSKRLSPQPQIRAATTQLVSNSGLAVSGKENKLCTPVICSSSTKEAEDAPEKLSR ASDMKDTQLLKKIKEAIGKIPAATKEPEEQTACHGPSGCLSNSLQVKGNTVCDGSVFTSDLMSDWSISSFSTFTSRDEQDFRNGLAALDA -------------------------------------------------------------- >85734_85734_7_SPG11-CCDC14_SPG11_chr15_44925703_ENST00000558319_CCDC14_chr3_123667979_ENST00000310351_length(transcript)=5458nt_BP=1766nt GAAAGTGACCGGAAGTAACCGCCGGGCCAAGATGGCTGCAGAGGAAGGGGTCGCGAGTGCTGCTTCCGCCGGCGGTAGCTGGGGCACCGC GGCCATGGGGCGGGTTCTACCGATGCTGTTGGTGCCAGTCCCCGCCGAGGCGATGGGGCAGCTCGGCTCCCGGGCGCAGCTGCGCACACA GCCGGAGGCTCTGGGGAGCCTGACGGCTGCGGGCAGCCTCCAAGTGCTTTCTTTGACGCCTGGCAGCCGGGGCGGGGGTCGCTGCTGCCT GGAGGGCCCCTTCTGGCACTTTCTATGGGAGGATTCTCGTAACAGCAGCACACCAACTGAAAAGCCCAAACTGCTCGCTCTTGGTGAAAA TTATGAACTGCTTATCTATGAATTTAATTTGAAAGATGGAAGATGTGATGCAACCATTTTGTATAGCTGTAGTAGGGAGGCATTGCAAAA GCTCATTGACGATCAAGATATCAGTATTTCCTTATTGTCTTTGAGAATCCTGTCATTTCACAATAACACATCATTACTGTTCATCAACAA ATGTGTCATCCTACATATTATATTTCCTGAAAGAGATGCTGCAATTAGAGTACTCAACTGTTTCACACTTCCCTTGCCTGCACAGGCAGT GGACATGATTATTGACACGCAGCTCTGCAGAGGAATTCTTTTTGTTTTGAGTAGTTTAGGCTGGATCTACATTTTTGATGTTGTGGATGG TACATATGTAGCTCATGTGGATTTAGCACTTCACAAAGAAGACATGTGTAATGAGCAGCAACAGGAGCCAGCCAAGATTTCTTCATTTAC TTCACTGAAAGTTTCTCAAGACCTCGATGTTGCAGTGATTGTCAGCTCCTCCAACTCCGCAGTTGCTCTTAACTTAAATTTGTATTTCAG GCAACACCCAGGACACCTACTGTGTGAAAGAATACTAGAAGATCTTCCTATTCAAGGACCTAAGGGCGTAGATGAAGATGATCCTGTTAA CTCTGCCTACAACATGAAACTGGCCAAGTTTTCCTTCCAAATTGATAGGTCTTGGAAAGCCCAGCTATCATCATTGAATGAAACAATAAA GAACTCCAAACTGGAGGTTTCCTGTTGTGCTCCATGGTTCCAGGATATTTTGCATTTGGAGTCACCTGAATCTGGTAACCACAGTACAAG TGTGCAGAGCTGGGCCTTCATTCCACAGGACATAATGCATGGGCAATATAATGTTCTACAGAAAGATCATGCCAAGACCAGTGATCCAGG AAGATCATGGAAAATAATGCACATCAGTGAACAAGAGGAACCCATAGAGCTTAAATGTGTGTCTGTGACAGGATTCACTGCACTGTTTAC TTGGGAAGTGGAAAGGATGGGCTATACCATTACCCTCTGGGATTTGGAGACCCAGGGCATGCAGTGTTTTTCCCTTGGCACAAAGTGTAT TCCTGTAGACAGTAGTGGAGACCAGCAGCTGTGCTTTGTTTTGACAGAGAATGGACTCTCTCTGATTTTGTTTGGTTTGACTCAAGAAGA GTTTTTAAACAGACTCATGATCCATGGAAGTGCCAGCACTGTGGACACTCTTTGTCATCTCAATGGCTGGGGAAGGTGCTCAATTCCCAT ACATGCACTAGAGGCCGGGATAGAAAATCGTCAGCTGGACACAGTAAATTTCTTTTTGAAGAGCAAGGAAAATCTTTTTAATCCATCCTC AAAATCTTCTGTATCTGATCAGTTTGATCACTTGTCATCCCATTTATATTTAAGAACATCTTCAGATAATAAGAAACAGATACCTAATGA AGCTTCTGCTAGAAGTGAAAGAGACACATCAGACCTAGAGCAAAACTGGTCATTGCAAGATCATTATAGAATGTATTCACCCATAATATA CCAAGCCCTCTGTGAGCACGTGCAGACTCAGATGTCACTGATGAATGACTTGACTTCAAAGAACATCCCTAATGGAATTCCTGCTGTACC ATGCCATGCTCCCTCTCATTCTGAATCTCAGGCAACTCCTCATTCTAGTTATGGCTTATGTACCTCCACCCCAGTCTGGTCACTTCAGCG GCCACCCTGCCCTCCAAAGGTTCATTCTGAAGTTCAAACTGATGGCAACAGTCAGTTTGCATCACAAGGTAAAACAGTTTCTGCAACCTG TACTGATGTTCTACGGAATTCATTTAATACCAGTCCTGGAGTTCCATGTAGCCTGCCCAAAACTGACATATCAGCTATTCCAACATTGCA GCAACTGGGCCTTGTTAATGGAATTCTGCCACAACAAGGAATTCATAAGGAAACAGACCTACTAAAATGTATTCAAACATATTTGTCTCT TTTTCGATCTCATGGAAAAGAAACGCATCTGGACAGTCAGACACACCGAAGCCCTACTCAGTCACAACCAGCTTTCTTGGCCACTAATGA AGAAAAATGTGCCAGAGAGCAAATTAGAGAGGCCACAAGTGAAAGAAAGGATTTAAACATACATGTGCGAGATACAAAAACAGTGAAGGA TGTACAGAAGGCAAAAAATGTGAACAAGACAGCTGAAAAAGTTAGAATTATAAAATATTTGTTGGGAGAGCTCAAGGCCCTGGTAGCAGA ACAAGAGGATTCAGAAATTCAGAGGTTGATTACAGAAATGGAGGCATGTATATCTGTACTTCCAACAGTAAGTGGAAACACAGATATTCA AGTTGAGATAGCACTGGCCATGCAACCATTAAGAAGTGAGAATGCTCAGTTACGAAGGCAGTTGAGAATTTTGAACCAGCAACTCAGAGA ACAACAGAAAACTCAAAAACCATCTGGTGCTGTGGATTGCAACCTTGAATTGTTTTCTCTTCAGTCATTGAATATGTCACTGCAAAATCA ATTGGAGGAGTCACTAAAGAGCCAGGAATTACTGCAGAGTAAAAATGAAGAGCTGTTAAAAGTGATTGAAAATCAGAAAGATGAAAACAA AAAATTTAGTAGTATATTTAAAGACAAAGATCAAACTATACTTGAAAATAAACAGCAATATGATATTGAGATAACAAGAATAAAAATTGA ATTGGAGGAAGCCCTAGTCAATGTGAAAAGCTCCCAGTTTAAGTTAGAAACTGCTGAAAAGGAAAACCAGATATTGGGGATAACATTACG TCAGCGTGATGCTGAGGTGACTCGACTAAGAGAATTAACCAGAACTTTACAGACTAGCATGGCAAAGCTTCTCTCCGATCTTAGTGTGGA CAGTGCTCGCTGCAAGCCTGGGAATAACCTTACCAAATCACTCTTGAACATTCATGATAAACAACTTCAACATGACCCAGCTCCTGCTCA CACTTCCATAATGAGCTATCTAAATAAGTTAGAAACAAATTACAGTTTTACACATTCAGAGCCACTTTCTACAATTAAAAATGAGGAAAC CATAGAGCCAGACAAAACCTATGAAAATGTTCTGTCCTCCAGAGGCCCTCAAAATAGTAACACTAGGGGCATGGAGGAAGCATCTGCACC TGGAATTATTTCTGCCCTTTCAAAACAGGATTCTGATGAAGGGAGTGAAACTATGGCTTTAATAGAAGATGAGCATAATTTGGATAATAC AATTTACATTCCTTTTGCTAGAAGCACTCCTGAAAAGAAATCACCACTTTCTAAGAGACTATCCCCTCAGCCACAAATAAGAGCAGCTAC AACACAGCTAGTCAGCAACAGCGGACTTGCTGTCTCTGGAAAAGAAAATAAACTGTGTACACCTGTAATCTGTTCCTCTTCAACAAAGGA AGCAGAAGATGCACCTGAAAAACTTTCCAGAGCATCTGATATGAAGGACACACAGCTCCTCAAGAAAATAAAGGAAGCAATTGGTAAGAT CCCTGCTGCCACCAAGGAGCCAGAGGAACAAACTGCATGTCATGGCCCATCAGGTTGTCTTAGCAACAGCCTTCAAGTGAAAGGCAATAC TGTCTGTGATGGTAGTGTTTTCACTTCTGACTTGATGTCTGACTGGAGCATCTCTTCGTTTTCAACGTTCACTTCTCGTGATGAACAAGA CTTCAGAAATGGCCTTGCGGCATTAGATGCCAACATAGCTAGACTCCAGAAGTCTTTAAGGACTGGTCTTCTGGAGAAATGAATTCAGAA GAAAACTCATCAGGTGCTTCTTTTTAAAACTAGAACTTGGCTATATTGAATGTGTATTTTTCTTTAGTGAAATGATGTTTTATGTTATTA TGTGTGAAGTAATATATTGTACAAGTAATAAATGTATTGTTGAGATATATTGACACTGAGGAGCTTATAAAAACAAGTCATCTTAAGTTC ACAATTGCTACAAGAAGAAAGTTGTGGATAACTAGGAAATTATTGTAAGTAATGTTTTATTTCAGTACTTAGCAATTAGAGTTCTTTTAT TAAGATGTATCTGCTGGATTAAGGGTACAGGTTGAAATAGTTCTGTGGCTGTCCTAAGAAATAATGGGAAAAGAATCTCTGGATGTAAGT TTTTCTGTTGAAACTAGAGGGTTTTTTTTTTCTGTTTACATATACTTTTTTTTAATAGCAATGTGTTTTTATTAAACATGCTGTGTGCCA CAGGCCAGTGTTGTTGGTGAAATATATAAACATTTATTTAAAGAGAAAAGTTACCAGTATCTACACCTCTTAAAAAACATTGATTGGTCT AAAAAATATATAGATAACATCCTAAGTTAACATATGGCTTCTTAAAACTTGGGCACTTTTATTTGTTTTTATCCCAAATTCATGTTTTAA GGCCTTTAAAGAATAGTCAGACTGATAAAGAAGTGCTAACAGATAAGCTATAGTTGGGGAAATTTGTGGGTTTTTTTTAAATAAGAAATG TTTATTTTTGTCCTTATATTTAAACATGATGGAATTTGTAAATCTTGGCATTGATTGTAATTCTGCCTTTTTGGAAGAATTTTTTCTCCC AGCATGTTAGCTGAGAATATTCTCTATTTTATAAATAATATGAAGTAGGTTGGTCTCTCTGCTTCTCTATACCAGGACTTCTTAGCTCAG TATCATCTCCCTTCATGTAAGCAGCACGTTTTAACTCTTAGGAAGCTGAATGTTGTGTTATCACTAATACTTTGTACAGGTCACCTGCCT ACTCTAATTGTCCTTAGTACTTGGACAGGCTTTATCATTAAAGAGTGTTCTCCTAATCCCAGAACCTCCTCGTGTTTTTTGTTTTTTTGG TGGTTTTTTTTTTTTTTTTAGGTGTTAGTGCTACAGCGTTTGAAGGAGCCAGCTGTAGTCTCTTTGATATGTTCAGATTTTCCAGATAGA GATTTAAGTCTAAAAATTTATTAAGTGAATTCTAAACTATTTCACACAAGAGTCCATTAGCATCTTTAATTTTATTTAGTATTCATGAAT >85734_85734_7_SPG11-CCDC14_SPG11_chr15_44925703_ENST00000558319_CCDC14_chr3_123667979_ENST00000310351_length(amino acids)=1366AA_BP=579 MAAEEGVASAASAGGSWGTAAMGRVLPMLLVPVPAEAMGQLGSRAQLRTQPEALGSLTAAGSLQVLSLTPGSRGGGRCCLEGPFWHFLWE DSRNSSTPTEKPKLLALGENYELLIYEFNLKDGRCDATILYSCSREALQKLIDDQDISISLLSLRILSFHNNTSLLFINKCVILHIIFPE RDAAIRVLNCFTLPLPAQAVDMIIDTQLCRGILFVLSSLGWIYIFDVVDGTYVAHVDLALHKEDMCNEQQQEPAKISSFTSLKVSQDLDV AVIVSSSNSAVALNLNLYFRQHPGHLLCERILEDLPIQGPKGVDEDDPVNSAYNMKLAKFSFQIDRSWKAQLSSLNETIKNSKLEVSCCA PWFQDILHLESPESGNHSTSVQSWAFIPQDIMHGQYNVLQKDHAKTSDPGRSWKIMHISEQEEPIELKCVSVTGFTALFTWEVERMGYTI TLWDLETQGMQCFSLGTKCIPVDSSGDQQLCFVLTENGLSLILFGLTQEEFLNRLMIHGSASTVDTLCHLNGWGRCSIPIHALEAGIENR QLDTVNFFLKSKENLFNPSSKSSVSDQFDHLSSHLYLRTSSDNKKQIPNEASARSERDTSDLEQNWSLQDHYRMYSPIIYQALCEHVQTQ MSLMNDLTSKNIPNGIPAVPCHAPSHSESQATPHSSYGLCTSTPVWSLQRPPCPPKVHSEVQTDGNSQFASQGKTVSATCTDVLRNSFNT SPGVPCSLPKTDISAIPTLQQLGLVNGILPQQGIHKETDLLKCIQTYLSLFRSHGKETHLDSQTHRSPTQSQPAFLATNEEKCAREQIRE ATSERKDLNIHVRDTKTVKDVQKAKNVNKTAEKVRIIKYLLGELKALVAEQEDSEIQRLITEMEACISVLPTVSGNTDIQVEIALAMQPL RSENAQLRRQLRILNQQLREQQKTQKPSGAVDCNLELFSLQSLNMSLQNQLEESLKSQELLQSKNEELLKVIENQKDENKKFSSIFKDKD QTILENKQQYDIEITRIKIELEEALVNVKSSQFKLETAEKENQILGITLRQRDAEVTRLRELTRTLQTSMAKLLSDLSVDSARCKPGNNL TKSLLNIHDKQLQHDPAPAHTSIMSYLNKLETNYSFTHSEPLSTIKNEETIEPDKTYENVLSSRGPQNSNTRGMEEASAPGIISALSKQD SDEGSETMALIEDEHNLDNTIYIPFARSTPEKKSPLSKRLSPQPQIRAATTQLVSNSGLAVSGKENKLCTPVICSSSTKEAEDAPEKLSR ASDMKDTQLLKKIKEAIGKIPAATKEPEEQTACHGPSGCLSNSLQVKGNTVCDGSVFTSDLMSDWSISSFSTFTSRDEQDFRNGLAALDA -------------------------------------------------------------- >85734_85734_8_SPG11-CCDC14_SPG11_chr15_44925703_ENST00000558319_CCDC14_chr3_123667979_ENST00000488653_length(transcript)=5458nt_BP=1766nt GAAAGTGACCGGAAGTAACCGCCGGGCCAAGATGGCTGCAGAGGAAGGGGTCGCGAGTGCTGCTTCCGCCGGCGGTAGCTGGGGCACCGC GGCCATGGGGCGGGTTCTACCGATGCTGTTGGTGCCAGTCCCCGCCGAGGCGATGGGGCAGCTCGGCTCCCGGGCGCAGCTGCGCACACA GCCGGAGGCTCTGGGGAGCCTGACGGCTGCGGGCAGCCTCCAAGTGCTTTCTTTGACGCCTGGCAGCCGGGGCGGGGGTCGCTGCTGCCT GGAGGGCCCCTTCTGGCACTTTCTATGGGAGGATTCTCGTAACAGCAGCACACCAACTGAAAAGCCCAAACTGCTCGCTCTTGGTGAAAA TTATGAACTGCTTATCTATGAATTTAATTTGAAAGATGGAAGATGTGATGCAACCATTTTGTATAGCTGTAGTAGGGAGGCATTGCAAAA GCTCATTGACGATCAAGATATCAGTATTTCCTTATTGTCTTTGAGAATCCTGTCATTTCACAATAACACATCATTACTGTTCATCAACAA ATGTGTCATCCTACATATTATATTTCCTGAAAGAGATGCTGCAATTAGAGTACTCAACTGTTTCACACTTCCCTTGCCTGCACAGGCAGT GGACATGATTATTGACACGCAGCTCTGCAGAGGAATTCTTTTTGTTTTGAGTAGTTTAGGCTGGATCTACATTTTTGATGTTGTGGATGG TACATATGTAGCTCATGTGGATTTAGCACTTCACAAAGAAGACATGTGTAATGAGCAGCAACAGGAGCCAGCCAAGATTTCTTCATTTAC TTCACTGAAAGTTTCTCAAGACCTCGATGTTGCAGTGATTGTCAGCTCCTCCAACTCCGCAGTTGCTCTTAACTTAAATTTGTATTTCAG GCAACACCCAGGACACCTACTGTGTGAAAGAATACTAGAAGATCTTCCTATTCAAGGACCTAAGGGCGTAGATGAAGATGATCCTGTTAA CTCTGCCTACAACATGAAACTGGCCAAGTTTTCCTTCCAAATTGATAGGTCTTGGAAAGCCCAGCTATCATCATTGAATGAAACAATAAA GAACTCCAAACTGGAGGTTTCCTGTTGTGCTCCATGGTTCCAGGATATTTTGCATTTGGAGTCACCTGAATCTGGTAACCACAGTACAAG TGTGCAGAGCTGGGCCTTCATTCCACAGGACATAATGCATGGGCAATATAATGTTCTACAGAAAGATCATGCCAAGACCAGTGATCCAGG AAGATCATGGAAAATAATGCACATCAGTGAACAAGAGGAACCCATAGAGCTTAAATGTGTGTCTGTGACAGGATTCACTGCACTGTTTAC TTGGGAAGTGGAAAGGATGGGCTATACCATTACCCTCTGGGATTTGGAGACCCAGGGCATGCAGTGTTTTTCCCTTGGCACAAAGTGTAT TCCTGTAGACAGTAGTGGAGACCAGCAGCTGTGCTTTGTTTTGACAGAGAATGGACTCTCTCTGATTTTGTTTGGTTTGACTCAAGAAGA GTTTTTAAACAGACTCATGATCCATGGAAGTGCCAGCACTGTGGACACTCTTTGTCATCTCAATGGCTGGGGAAGGTGCTCAATTCCCAT ACATGCACTAGAGGCCGGGATAGAAAATCGTCAGCTGGACACAGTAAATTTCTTTTTGAAGAGCAAGGAAAATCTTTTTAATCCATCCTC AAAATCTTCTGTATCTGATCAGTTTGATCACTTGTCATCCCATTTATATTTAAGAACATCTTCAGATAATAAGAAACAGATACCTAATGA AGCTTCTGCTAGAAGTGAAAGAGACACATCAGACCTAGAGCAAAACTGGTCATTGCAAGATCATTATAGAATGTATTCACCCATAATATA CCAAGCCCTCTGTGAGCACGTGCAGACTCAGATGTCACTGATGAATGACTTGACTTCAAAGAACATCCCTAATGGAATTCCTGCTGTACC ATGCCATGCTCCCTCTCATTCTGAATCTCAGGCAACTCCTCATTCTAGTTATGGCTTATGTACCTCCACCCCAGTCTGGTCACTTCAGCG GCCACCCTGCCCTCCAAAGGTTCATTCTGAAGTTCAAACTGATGGCAACAGTCAGTTTGCATCACAAGGTAAAACAGTTTCTGCAACCTG TACTGATGTTCTACGGAATTCATTTAATACCAGTCCTGGAGTTCCATGTAGCCTGCCCAAAACTGACATATCAGCTATTCCAACATTGCA GCAACTGGGCCTTGTTAATGGAATTCTGCCACAACAAGGAATTCATAAGGAAACAGACCTACTAAAATGTATTCAAACATATTTGTCTCT TTTTCGATCTCATGGAAAAGAAACGCATCTGGACAGTCAGACACACCGAAGCCCTACTCAGTCACAACCAGCTTTCTTGGCCACTAATGA AGAAAAATGTGCCAGAGAGCAAATTAGAGAGGCCACAAGTGAAAGAAAGGATTTAAACATACATGTGCGAGATACAAAAACAGTGAAGGA TGTACAGAAGGCAAAAAATGTGAACAAGACAGCTGAAAAAGTTAGAATTATAAAATATTTGTTGGGAGAGCTCAAGGCCCTGGTAGCAGA ACAAGAGGATTCAGAAATTCAGAGGTTGATTACAGAAATGGAGGCATGTATATCTGTACTTCCAACAGTAAGTGGAAACACAGATATTCA AGTTGAGATAGCACTGGCCATGCAACCATTAAGAAGTGAGAATGCTCAGTTACGAAGGCAGTTGAGAATTTTGAACCAGCAACTCAGAGA ACAACAGAAAACTCAAAAACCATCTGGTGCTGTGGATTGCAACCTTGAATTGTTTTCTCTTCAGTCATTGAATATGTCACTGCAAAATCA ATTGGAGGAGTCACTAAAGAGCCAGGAATTACTGCAGAGTAAAAATGAAGAGCTGTTAAAAGTGATTGAAAATCAGAAAGATGAAAACAA AAAATTTAGTAGTATATTTAAAGACAAAGATCAAACTATACTTGAAAATAAACAGCAATATGATATTGAGATAACAAGAATAAAAATTGA ATTGGAGGAAGCCCTAGTCAATGTGAAAAGCTCCCAGTTTAAGTTAGAAACTGCTGAAAAGGAAAACCAGATATTGGGGATAACATTACG TCAGCGTGATGCTGAGGTGACTCGACTAAGAGAATTAACCAGAACTTTACAGACTAGCATGGCAAAGCTTCTCTCCGATCTTAGTGTGGA CAGTGCTCGCTGCAAGCCTGGGAATAACCTTACCAAATCACTCTTGAACATTCATGATAAACAACTTCAACATGACCCAGCTCCTGCTCA CACTTCCATAATGAGCTATCTAAATAAGTTAGAAACAAATTACAGTTTTACACATTCAGAGCCACTTTCTACAATTAAAAATGAGGAAAC CATAGAGCCAGACAAAACCTATGAAAATGTTCTGTCCTCCAGAGGCCCTCAAAATAGTAACACTAGGGGCATGGAGGAAGCATCTGCACC TGGAATTATTTCTGCCCTTTCAAAACAGGATTCTGATGAAGGGAGTGAAACTATGGCTTTAATAGAAGATGAGCATAATTTGGATAATAC AATTTACATTCCTTTTGCTAGAAGCACTCCTGAAAAGAAATCACCACTTTCTAAGAGACTATCCCCTCAGCCACAAATAAGAGCAGCTAC AACACAGCTAGTCAGCAACAGCGGACTTGCTGTCTCTGGAAAAGAAAATAAACTGTGTACACCTGTAATCTGTTCCTCTTCAACAAAGGA AGCAGAAGATGCACCTGAAAAACTTTCCAGAGCATCTGATATGAAGGACACACAGCTCCTCAAGAAAATAAAGGAAGCAATTGGTAAGAT CCCTGCTGCCACCAAGGAGCCAGAGGAACAAACTGCATGTCATGGCCCATCAGGTTGTCTTAGCAACAGCCTTCAAGTGAAAGGCAATAC TGTCTGTGATGGTAGTGTTTTCACTTCTGACTTGATGTCTGACTGGAGCATCTCTTCGTTTTCAACGTTCACTTCTCGTGATGAACAAGA CTTCAGAAATGGCCTTGCGGCATTAGATGCCAACATAGCTAGACTCCAGAAGTCTTTAAGGACTGGTCTTCTGGAGAAATGAATTCAGAA GAAAACTCATCAGGTGCTTCTTTTTAAAACTAGAACTTGGCTATATTGAATGTGTATTTTTCTTTAGTGAAATGATGTTTTATGTTATTA TGTGTGAAGTAATATATTGTACAAGTAATAAATGTATTGTTGAGATATATTGACACTGAGGAGCTTATAAAAACAAGTCATCTTAAGTTC ACAATTGCTACAAGAAGAAAGTTGTGGATAACTAGGAAATTATTGTAAGTAATGTTTTATTTCAGTACTTAGCAATTAGAGTTCTTTTAT TAAGATGTATCTGCTGGATTAAGGGTACAGGTTGAAATAGTTCTGTGGCTGTCCTAAGAAATAATGGGAAAAGAATCTCTGGATGTAAGT TTTTCTGTTGAAACTAGAGGGTTTTTTTTTTCTGTTTACATATACTTTTTTTTAATAGCAATGTGTTTTTATTAAACATGCTGTGTGCCA CAGGCCAGTGTTGTTGGTGAAATATATAAACATTTATTTAAAGAGAAAAGTTACCAGTATCTACACCTCTTAAAAAACATTGATTGGTCT AAAAAATATATAGATAACATCCTAAGTTAACATATGGCTTCTTAAAACTTGGGCACTTTTATTTGTTTTTATCCCAAATTCATGTTTTAA GGCCTTTAAAGAATAGTCAGACTGATAAAGAAGTGCTAACAGATAAGCTATAGTTGGGGAAATTTGTGGGTTTTTTTTAAATAAGAAATG TTTATTTTTGTCCTTATATTTAAACATGATGGAATTTGTAAATCTTGGCATTGATTGTAATTCTGCCTTTTTGGAAGAATTTTTTCTCCC AGCATGTTAGCTGAGAATATTCTCTATTTTATAAATAATATGAAGTAGGTTGGTCTCTCTGCTTCTCTATACCAGGACTTCTTAGCTCAG TATCATCTCCCTTCATGTAAGCAGCACGTTTTAACTCTTAGGAAGCTGAATGTTGTGTTATCACTAATACTTTGTACAGGTCACCTGCCT ACTCTAATTGTCCTTAGTACTTGGACAGGCTTTATCATTAAAGAGTGTTCTCCTAATCCCAGAACCTCCTCGTGTTTTTTGTTTTTTTGG TGGTTTTTTTTTTTTTTTTAGGTGTTAGTGCTACAGCGTTTGAAGGAGCCAGCTGTAGTCTCTTTGATATGTTCAGATTTTCCAGATAGA GATTTAAGTCTAAAAATTTATTAAGTGAATTCTAAACTATTTCACACAAGAGTCCATTAGCATCTTTAATTTTATTTAGTATTCATGAAT >85734_85734_8_SPG11-CCDC14_SPG11_chr15_44925703_ENST00000558319_CCDC14_chr3_123667979_ENST00000488653_length(amino acids)=1366AA_BP=579 MAAEEGVASAASAGGSWGTAAMGRVLPMLLVPVPAEAMGQLGSRAQLRTQPEALGSLTAAGSLQVLSLTPGSRGGGRCCLEGPFWHFLWE DSRNSSTPTEKPKLLALGENYELLIYEFNLKDGRCDATILYSCSREALQKLIDDQDISISLLSLRILSFHNNTSLLFINKCVILHIIFPE RDAAIRVLNCFTLPLPAQAVDMIIDTQLCRGILFVLSSLGWIYIFDVVDGTYVAHVDLALHKEDMCNEQQQEPAKISSFTSLKVSQDLDV AVIVSSSNSAVALNLNLYFRQHPGHLLCERILEDLPIQGPKGVDEDDPVNSAYNMKLAKFSFQIDRSWKAQLSSLNETIKNSKLEVSCCA PWFQDILHLESPESGNHSTSVQSWAFIPQDIMHGQYNVLQKDHAKTSDPGRSWKIMHISEQEEPIELKCVSVTGFTALFTWEVERMGYTI TLWDLETQGMQCFSLGTKCIPVDSSGDQQLCFVLTENGLSLILFGLTQEEFLNRLMIHGSASTVDTLCHLNGWGRCSIPIHALEAGIENR QLDTVNFFLKSKENLFNPSSKSSVSDQFDHLSSHLYLRTSSDNKKQIPNEASARSERDTSDLEQNWSLQDHYRMYSPIIYQALCEHVQTQ MSLMNDLTSKNIPNGIPAVPCHAPSHSESQATPHSSYGLCTSTPVWSLQRPPCPPKVHSEVQTDGNSQFASQGKTVSATCTDVLRNSFNT SPGVPCSLPKTDISAIPTLQQLGLVNGILPQQGIHKETDLLKCIQTYLSLFRSHGKETHLDSQTHRSPTQSQPAFLATNEEKCAREQIRE ATSERKDLNIHVRDTKTVKDVQKAKNVNKTAEKVRIIKYLLGELKALVAEQEDSEIQRLITEMEACISVLPTVSGNTDIQVEIALAMQPL RSENAQLRRQLRILNQQLREQQKTQKPSGAVDCNLELFSLQSLNMSLQNQLEESLKSQELLQSKNEELLKVIENQKDENKKFSSIFKDKD QTILENKQQYDIEITRIKIELEEALVNVKSSQFKLETAEKENQILGITLRQRDAEVTRLRELTRTLQTSMAKLLSDLSVDSARCKPGNNL TKSLLNIHDKQLQHDPAPAHTSIMSYLNKLETNYSFTHSEPLSTIKNEETIEPDKTYENVLSSRGPQNSNTRGMEEASAPGIISALSKQD SDEGSETMALIEDEHNLDNTIYIPFARSTPEKKSPLSKRLSPQPQIRAATTQLVSNSGLAVSGKENKLCTPVICSSSTKEAEDAPEKLSR ASDMKDTQLLKKIKEAIGKIPAATKEPEEQTACHGPSGCLSNSLQVKGNTVCDGSVFTSDLMSDWSISSFSTFTSRDEQDFRNGLAALDA -------------------------------------------------------------- >85734_85734_9_SPG11-CCDC14_SPG11_chr15_44925703_ENST00000559193_CCDC14_chr3_123667979_ENST00000310351_length(transcript)=5438nt_BP=1746nt GCCGGGCCAAGATGGCTGCAGAGGAAGGGGTCGCGAGTGCTGCTTCCGCCGGCGGTAGCTGGGGCACCGCGGCCATGGGGCGGGTTCTAC CGATGCTGTTGGTGCCAGTCCCCGCCGAGGCGATGGGGCAGCTCGGCTCCCGGGCGCAGCTGCGCACACAGCCGGAGGCTCTGGGGAGCC TGACGGCTGCGGGCAGCCTCCAAGTGCTTTCTTTGACGCCTGGCAGCCGGGGCGGGGGTCGCTGCTGCCTGGAGGGCCCCTTCTGGCACT TTCTATGGGAGGATTCTCGTAACAGCAGCACACCAACTGAAAAGCCCAAACTGCTCGCTCTTGGTGAAAATTATGAACTGCTTATCTATG AATTTAATTTGAAAGATGGAAGATGTGATGCAACCATTTTGTATAGCTGTAGTAGGGAGGCATTGCAAAAGCTCATTGACGATCAAGATA TCAGTATTTCCTTATTGTCTTTGAGAATCCTGTCATTTCACAATAACACATCATTACTGTTCATCAACAAATGTGTCATCCTACATATTA TATTTCCTGAAAGAGATGCTGCAATTAGAGTACTCAACTGTTTCACACTTCCCTTGCCTGCACAGGCAGTGGACATGATTATTGACACGC AGCTCTGCAGAGGAATTCTTTTTGTTTTGAGTAGTTTAGGCTGGATCTACATTTTTGATGTTGTGGATGGTACATATGTAGCTCATGTGG ATTTAGCACTTCACAAAGAAGACATGTGTAATGAGCAGCAACAGGAGCCAGCCAAGATTTCTTCATTTACTTCACTGAAAGTTTCTCAAG ACCTCGATGTTGCAGTGATTGTCAGCTCCTCCAACTCCGCAGTTGCTCTTAACTTAAATTTGTATTTCAGGCAACACCCAGGACACCTAC TGTGTGAAAGAATACTAGAAGATCTTCCTATTCAAGGACCTAAGGGCGTAGATGAAGATGATCCTGTTAACTCTGCCTACAACATGAAAC TGGCCAAGTTTTCCTTCCAAATTGATAGGTCTTGGAAAGCCCAGCTATCATCATTGAATGAAACAATAAAGAACTCCAAACTGGAGGTTT CCTGTTGTGCTCCATGGTTCCAGGATATTTTGCATTTGGAGTCACCTGAATCTGGTAACCACAGTACAAGTGTGCAGAGCTGGGCCTTCA TTCCACAGGACATAATGCATGGGCAATATAATGTTCTACAGAAAGATCATGCCAAGACCAGTGATCCAGGAAGATCATGGAAAATAATGC ACATCAGTGAACAAGAGGAACCCATAGAGCTTAAATGTGTGTCTGTGACAGGATTCACTGCACTGTTTACTTGGGAAGTGGAAAGGATGG GCTATACCATTACCCTCTGGGATTTGGAGACCCAGGGCATGCAGTGTTTTTCCCTTGGCACAAAGTGTATTCCTGTAGACAGTAGTGGAG ACCAGCAGCTGTGCTTTGTTTTGACAGAGAATGGACTCTCTCTGATTTTGTTTGGTTTGACTCAAGAAGAGTTTTTAAACAGACTCATGA TCCATGGAAGTGCCAGCACTGTGGACACTCTTTGTCATCTCAATGGCTGGGGAAGGTGCTCAATTCCCATACATGCACTAGAGGCCGGGA TAGAAAATCGTCAGCTGGACACAGTAAATTTCTTTTTGAAGAGCAAGGAAAATCTTTTTAATCCATCCTCAAAATCTTCTGTATCTGATC AGTTTGATCACTTGTCATCCCATTTATATTTAAGAACATCTTCAGATAATAAGAAACAGATACCTAATGAAGCTTCTGCTAGAAGTGAAA GAGACACATCAGACCTAGAGCAAAACTGGTCATTGCAAGATCATTATAGAATGTATTCACCCATAATATACCAAGCCCTCTGTGAGCACG TGCAGACTCAGATGTCACTGATGAATGACTTGACTTCAAAGAACATCCCTAATGGAATTCCTGCTGTACCATGCCATGCTCCCTCTCATT CTGAATCTCAGGCAACTCCTCATTCTAGTTATGGCTTATGTACCTCCACCCCAGTCTGGTCACTTCAGCGGCCACCCTGCCCTCCAAAGG TTCATTCTGAAGTTCAAACTGATGGCAACAGTCAGTTTGCATCACAAGGTAAAACAGTTTCTGCAACCTGTACTGATGTTCTACGGAATT CATTTAATACCAGTCCTGGAGTTCCATGTAGCCTGCCCAAAACTGACATATCAGCTATTCCAACATTGCAGCAACTGGGCCTTGTTAATG GAATTCTGCCACAACAAGGAATTCATAAGGAAACAGACCTACTAAAATGTATTCAAACATATTTGTCTCTTTTTCGATCTCATGGAAAAG AAACGCATCTGGACAGTCAGACACACCGAAGCCCTACTCAGTCACAACCAGCTTTCTTGGCCACTAATGAAGAAAAATGTGCCAGAGAGC AAATTAGAGAGGCCACAAGTGAAAGAAAGGATTTAAACATACATGTGCGAGATACAAAAACAGTGAAGGATGTACAGAAGGCAAAAAATG TGAACAAGACAGCTGAAAAAGTTAGAATTATAAAATATTTGTTGGGAGAGCTCAAGGCCCTGGTAGCAGAACAAGAGGATTCAGAAATTC AGAGGTTGATTACAGAAATGGAGGCATGTATATCTGTACTTCCAACAGTAAGTGGAAACACAGATATTCAAGTTGAGATAGCACTGGCCA TGCAACCATTAAGAAGTGAGAATGCTCAGTTACGAAGGCAGTTGAGAATTTTGAACCAGCAACTCAGAGAACAACAGAAAACTCAAAAAC CATCTGGTGCTGTGGATTGCAACCTTGAATTGTTTTCTCTTCAGTCATTGAATATGTCACTGCAAAATCAATTGGAGGAGTCACTAAAGA GCCAGGAATTACTGCAGAGTAAAAATGAAGAGCTGTTAAAAGTGATTGAAAATCAGAAAGATGAAAACAAAAAATTTAGTAGTATATTTA AAGACAAAGATCAAACTATACTTGAAAATAAACAGCAATATGATATTGAGATAACAAGAATAAAAATTGAATTGGAGGAAGCCCTAGTCA ATGTGAAAAGCTCCCAGTTTAAGTTAGAAACTGCTGAAAAGGAAAACCAGATATTGGGGATAACATTACGTCAGCGTGATGCTGAGGTGA CTCGACTAAGAGAATTAACCAGAACTTTACAGACTAGCATGGCAAAGCTTCTCTCCGATCTTAGTGTGGACAGTGCTCGCTGCAAGCCTG GGAATAACCTTACCAAATCACTCTTGAACATTCATGATAAACAACTTCAACATGACCCAGCTCCTGCTCACACTTCCATAATGAGCTATC TAAATAAGTTAGAAACAAATTACAGTTTTACACATTCAGAGCCACTTTCTACAATTAAAAATGAGGAAACCATAGAGCCAGACAAAACCT ATGAAAATGTTCTGTCCTCCAGAGGCCCTCAAAATAGTAACACTAGGGGCATGGAGGAAGCATCTGCACCTGGAATTATTTCTGCCCTTT CAAAACAGGATTCTGATGAAGGGAGTGAAACTATGGCTTTAATAGAAGATGAGCATAATTTGGATAATACAATTTACATTCCTTTTGCTA GAAGCACTCCTGAAAAGAAATCACCACTTTCTAAGAGACTATCCCCTCAGCCACAAATAAGAGCAGCTACAACACAGCTAGTCAGCAACA GCGGACTTGCTGTCTCTGGAAAAGAAAATAAACTGTGTACACCTGTAATCTGTTCCTCTTCAACAAAGGAAGCAGAAGATGCACCTGAAA AACTTTCCAGAGCATCTGATATGAAGGACACACAGCTCCTCAAGAAAATAAAGGAAGCAATTGGTAAGATCCCTGCTGCCACCAAGGAGC CAGAGGAACAAACTGCATGTCATGGCCCATCAGGTTGTCTTAGCAACAGCCTTCAAGTGAAAGGCAATACTGTCTGTGATGGTAGTGTTT TCACTTCTGACTTGATGTCTGACTGGAGCATCTCTTCGTTTTCAACGTTCACTTCTCGTGATGAACAAGACTTCAGAAATGGCCTTGCGG CATTAGATGCCAACATAGCTAGACTCCAGAAGTCTTTAAGGACTGGTCTTCTGGAGAAATGAATTCAGAAGAAAACTCATCAGGTGCTTC TTTTTAAAACTAGAACTTGGCTATATTGAATGTGTATTTTTCTTTAGTGAAATGATGTTTTATGTTATTATGTGTGAAGTAATATATTGT ACAAGTAATAAATGTATTGTTGAGATATATTGACACTGAGGAGCTTATAAAAACAAGTCATCTTAAGTTCACAATTGCTACAAGAAGAAA GTTGTGGATAACTAGGAAATTATTGTAAGTAATGTTTTATTTCAGTACTTAGCAATTAGAGTTCTTTTATTAAGATGTATCTGCTGGATT AAGGGTACAGGTTGAAATAGTTCTGTGGCTGTCCTAAGAAATAATGGGAAAAGAATCTCTGGATGTAAGTTTTTCTGTTGAAACTAGAGG GTTTTTTTTTTCTGTTTACATATACTTTTTTTTAATAGCAATGTGTTTTTATTAAACATGCTGTGTGCCACAGGCCAGTGTTGTTGGTGA AATATATAAACATTTATTTAAAGAGAAAAGTTACCAGTATCTACACCTCTTAAAAAACATTGATTGGTCTAAAAAATATATAGATAACAT CCTAAGTTAACATATGGCTTCTTAAAACTTGGGCACTTTTATTTGTTTTTATCCCAAATTCATGTTTTAAGGCCTTTAAAGAATAGTCAG ACTGATAAAGAAGTGCTAACAGATAAGCTATAGTTGGGGAAATTTGTGGGTTTTTTTTAAATAAGAAATGTTTATTTTTGTCCTTATATT TAAACATGATGGAATTTGTAAATCTTGGCATTGATTGTAATTCTGCCTTTTTGGAAGAATTTTTTCTCCCAGCATGTTAGCTGAGAATAT TCTCTATTTTATAAATAATATGAAGTAGGTTGGTCTCTCTGCTTCTCTATACCAGGACTTCTTAGCTCAGTATCATCTCCCTTCATGTAA GCAGCACGTTTTAACTCTTAGGAAGCTGAATGTTGTGTTATCACTAATACTTTGTACAGGTCACCTGCCTACTCTAATTGTCCTTAGTAC TTGGACAGGCTTTATCATTAAAGAGTGTTCTCCTAATCCCAGAACCTCCTCGTGTTTTTTGTTTTTTTGGTGGTTTTTTTTTTTTTTTTA GGTGTTAGTGCTACAGCGTTTGAAGGAGCCAGCTGTAGTCTCTTTGATATGTTCAGATTTTCCAGATAGAGATTTAAGTCTAAAAATTTA TTAAGTGAATTCTAAACTATTTCACACAAGAGTCCATTAGCATCTTTAATTTTATTTAGTATTCATGAATTAATTTATTGGCATCTTATT >85734_85734_9_SPG11-CCDC14_SPG11_chr15_44925703_ENST00000559193_CCDC14_chr3_123667979_ENST00000310351_length(amino acids)=1366AA_BP=579 MAAEEGVASAASAGGSWGTAAMGRVLPMLLVPVPAEAMGQLGSRAQLRTQPEALGSLTAAGSLQVLSLTPGSRGGGRCCLEGPFWHFLWE DSRNSSTPTEKPKLLALGENYELLIYEFNLKDGRCDATILYSCSREALQKLIDDQDISISLLSLRILSFHNNTSLLFINKCVILHIIFPE RDAAIRVLNCFTLPLPAQAVDMIIDTQLCRGILFVLSSLGWIYIFDVVDGTYVAHVDLALHKEDMCNEQQQEPAKISSFTSLKVSQDLDV AVIVSSSNSAVALNLNLYFRQHPGHLLCERILEDLPIQGPKGVDEDDPVNSAYNMKLAKFSFQIDRSWKAQLSSLNETIKNSKLEVSCCA PWFQDILHLESPESGNHSTSVQSWAFIPQDIMHGQYNVLQKDHAKTSDPGRSWKIMHISEQEEPIELKCVSVTGFTALFTWEVERMGYTI TLWDLETQGMQCFSLGTKCIPVDSSGDQQLCFVLTENGLSLILFGLTQEEFLNRLMIHGSASTVDTLCHLNGWGRCSIPIHALEAGIENR QLDTVNFFLKSKENLFNPSSKSSVSDQFDHLSSHLYLRTSSDNKKQIPNEASARSERDTSDLEQNWSLQDHYRMYSPIIYQALCEHVQTQ MSLMNDLTSKNIPNGIPAVPCHAPSHSESQATPHSSYGLCTSTPVWSLQRPPCPPKVHSEVQTDGNSQFASQGKTVSATCTDVLRNSFNT SPGVPCSLPKTDISAIPTLQQLGLVNGILPQQGIHKETDLLKCIQTYLSLFRSHGKETHLDSQTHRSPTQSQPAFLATNEEKCAREQIRE ATSERKDLNIHVRDTKTVKDVQKAKNVNKTAEKVRIIKYLLGELKALVAEQEDSEIQRLITEMEACISVLPTVSGNTDIQVEIALAMQPL RSENAQLRRQLRILNQQLREQQKTQKPSGAVDCNLELFSLQSLNMSLQNQLEESLKSQELLQSKNEELLKVIENQKDENKKFSSIFKDKD QTILENKQQYDIEITRIKIELEEALVNVKSSQFKLETAEKENQILGITLRQRDAEVTRLRELTRTLQTSMAKLLSDLSVDSARCKPGNNL TKSLLNIHDKQLQHDPAPAHTSIMSYLNKLETNYSFTHSEPLSTIKNEETIEPDKTYENVLSSRGPQNSNTRGMEEASAPGIISALSKQD SDEGSETMALIEDEHNLDNTIYIPFARSTPEKKSPLSKRLSPQPQIRAATTQLVSNSGLAVSGKENKLCTPVICSSSTKEAEDAPEKLSR ASDMKDTQLLKKIKEAIGKIPAATKEPEEQTACHGPSGCLSNSLQVKGNTVCDGSVFTSDLMSDWSISSFSTFTSRDEQDFRNGLAALDA -------------------------------------------------------------- >85734_85734_10_SPG11-CCDC14_SPG11_chr15_44925703_ENST00000559193_CCDC14_chr3_123667979_ENST00000488653_length(transcript)=5438nt_BP=1746nt GCCGGGCCAAGATGGCTGCAGAGGAAGGGGTCGCGAGTGCTGCTTCCGCCGGCGGTAGCTGGGGCACCGCGGCCATGGGGCGGGTTCTAC CGATGCTGTTGGTGCCAGTCCCCGCCGAGGCGATGGGGCAGCTCGGCTCCCGGGCGCAGCTGCGCACACAGCCGGAGGCTCTGGGGAGCC TGACGGCTGCGGGCAGCCTCCAAGTGCTTTCTTTGACGCCTGGCAGCCGGGGCGGGGGTCGCTGCTGCCTGGAGGGCCCCTTCTGGCACT TTCTATGGGAGGATTCTCGTAACAGCAGCACACCAACTGAAAAGCCCAAACTGCTCGCTCTTGGTGAAAATTATGAACTGCTTATCTATG AATTTAATTTGAAAGATGGAAGATGTGATGCAACCATTTTGTATAGCTGTAGTAGGGAGGCATTGCAAAAGCTCATTGACGATCAAGATA TCAGTATTTCCTTATTGTCTTTGAGAATCCTGTCATTTCACAATAACACATCATTACTGTTCATCAACAAATGTGTCATCCTACATATTA TATTTCCTGAAAGAGATGCTGCAATTAGAGTACTCAACTGTTTCACACTTCCCTTGCCTGCACAGGCAGTGGACATGATTATTGACACGC AGCTCTGCAGAGGAATTCTTTTTGTTTTGAGTAGTTTAGGCTGGATCTACATTTTTGATGTTGTGGATGGTACATATGTAGCTCATGTGG ATTTAGCACTTCACAAAGAAGACATGTGTAATGAGCAGCAACAGGAGCCAGCCAAGATTTCTTCATTTACTTCACTGAAAGTTTCTCAAG ACCTCGATGTTGCAGTGATTGTCAGCTCCTCCAACTCCGCAGTTGCTCTTAACTTAAATTTGTATTTCAGGCAACACCCAGGACACCTAC TGTGTGAAAGAATACTAGAAGATCTTCCTATTCAAGGACCTAAGGGCGTAGATGAAGATGATCCTGTTAACTCTGCCTACAACATGAAAC TGGCCAAGTTTTCCTTCCAAATTGATAGGTCTTGGAAAGCCCAGCTATCATCATTGAATGAAACAATAAAGAACTCCAAACTGGAGGTTT CCTGTTGTGCTCCATGGTTCCAGGATATTTTGCATTTGGAGTCACCTGAATCTGGTAACCACAGTACAAGTGTGCAGAGCTGGGCCTTCA TTCCACAGGACATAATGCATGGGCAATATAATGTTCTACAGAAAGATCATGCCAAGACCAGTGATCCAGGAAGATCATGGAAAATAATGC ACATCAGTGAACAAGAGGAACCCATAGAGCTTAAATGTGTGTCTGTGACAGGATTCACTGCACTGTTTACTTGGGAAGTGGAAAGGATGG GCTATACCATTACCCTCTGGGATTTGGAGACCCAGGGCATGCAGTGTTTTTCCCTTGGCACAAAGTGTATTCCTGTAGACAGTAGTGGAG ACCAGCAGCTGTGCTTTGTTTTGACAGAGAATGGACTCTCTCTGATTTTGTTTGGTTTGACTCAAGAAGAGTTTTTAAACAGACTCATGA TCCATGGAAGTGCCAGCACTGTGGACACTCTTTGTCATCTCAATGGCTGGGGAAGGTGCTCAATTCCCATACATGCACTAGAGGCCGGGA TAGAAAATCGTCAGCTGGACACAGTAAATTTCTTTTTGAAGAGCAAGGAAAATCTTTTTAATCCATCCTCAAAATCTTCTGTATCTGATC AGTTTGATCACTTGTCATCCCATTTATATTTAAGAACATCTTCAGATAATAAGAAACAGATACCTAATGAAGCTTCTGCTAGAAGTGAAA GAGACACATCAGACCTAGAGCAAAACTGGTCATTGCAAGATCATTATAGAATGTATTCACCCATAATATACCAAGCCCTCTGTGAGCACG TGCAGACTCAGATGTCACTGATGAATGACTTGACTTCAAAGAACATCCCTAATGGAATTCCTGCTGTACCATGCCATGCTCCCTCTCATT CTGAATCTCAGGCAACTCCTCATTCTAGTTATGGCTTATGTACCTCCACCCCAGTCTGGTCACTTCAGCGGCCACCCTGCCCTCCAAAGG TTCATTCTGAAGTTCAAACTGATGGCAACAGTCAGTTTGCATCACAAGGTAAAACAGTTTCTGCAACCTGTACTGATGTTCTACGGAATT CATTTAATACCAGTCCTGGAGTTCCATGTAGCCTGCCCAAAACTGACATATCAGCTATTCCAACATTGCAGCAACTGGGCCTTGTTAATG GAATTCTGCCACAACAAGGAATTCATAAGGAAACAGACCTACTAAAATGTATTCAAACATATTTGTCTCTTTTTCGATCTCATGGAAAAG AAACGCATCTGGACAGTCAGACACACCGAAGCCCTACTCAGTCACAACCAGCTTTCTTGGCCACTAATGAAGAAAAATGTGCCAGAGAGC AAATTAGAGAGGCCACAAGTGAAAGAAAGGATTTAAACATACATGTGCGAGATACAAAAACAGTGAAGGATGTACAGAAGGCAAAAAATG TGAACAAGACAGCTGAAAAAGTTAGAATTATAAAATATTTGTTGGGAGAGCTCAAGGCCCTGGTAGCAGAACAAGAGGATTCAGAAATTC AGAGGTTGATTACAGAAATGGAGGCATGTATATCTGTACTTCCAACAGTAAGTGGAAACACAGATATTCAAGTTGAGATAGCACTGGCCA TGCAACCATTAAGAAGTGAGAATGCTCAGTTACGAAGGCAGTTGAGAATTTTGAACCAGCAACTCAGAGAACAACAGAAAACTCAAAAAC CATCTGGTGCTGTGGATTGCAACCTTGAATTGTTTTCTCTTCAGTCATTGAATATGTCACTGCAAAATCAATTGGAGGAGTCACTAAAGA GCCAGGAATTACTGCAGAGTAAAAATGAAGAGCTGTTAAAAGTGATTGAAAATCAGAAAGATGAAAACAAAAAATTTAGTAGTATATTTA AAGACAAAGATCAAACTATACTTGAAAATAAACAGCAATATGATATTGAGATAACAAGAATAAAAATTGAATTGGAGGAAGCCCTAGTCA ATGTGAAAAGCTCCCAGTTTAAGTTAGAAACTGCTGAAAAGGAAAACCAGATATTGGGGATAACATTACGTCAGCGTGATGCTGAGGTGA CTCGACTAAGAGAATTAACCAGAACTTTACAGACTAGCATGGCAAAGCTTCTCTCCGATCTTAGTGTGGACAGTGCTCGCTGCAAGCCTG GGAATAACCTTACCAAATCACTCTTGAACATTCATGATAAACAACTTCAACATGACCCAGCTCCTGCTCACACTTCCATAATGAGCTATC TAAATAAGTTAGAAACAAATTACAGTTTTACACATTCAGAGCCACTTTCTACAATTAAAAATGAGGAAACCATAGAGCCAGACAAAACCT ATGAAAATGTTCTGTCCTCCAGAGGCCCTCAAAATAGTAACACTAGGGGCATGGAGGAAGCATCTGCACCTGGAATTATTTCTGCCCTTT CAAAACAGGATTCTGATGAAGGGAGTGAAACTATGGCTTTAATAGAAGATGAGCATAATTTGGATAATACAATTTACATTCCTTTTGCTA GAAGCACTCCTGAAAAGAAATCACCACTTTCTAAGAGACTATCCCCTCAGCCACAAATAAGAGCAGCTACAACACAGCTAGTCAGCAACA GCGGACTTGCTGTCTCTGGAAAAGAAAATAAACTGTGTACACCTGTAATCTGTTCCTCTTCAACAAAGGAAGCAGAAGATGCACCTGAAA AACTTTCCAGAGCATCTGATATGAAGGACACACAGCTCCTCAAGAAAATAAAGGAAGCAATTGGTAAGATCCCTGCTGCCACCAAGGAGC CAGAGGAACAAACTGCATGTCATGGCCCATCAGGTTGTCTTAGCAACAGCCTTCAAGTGAAAGGCAATACTGTCTGTGATGGTAGTGTTT TCACTTCTGACTTGATGTCTGACTGGAGCATCTCTTCGTTTTCAACGTTCACTTCTCGTGATGAACAAGACTTCAGAAATGGCCTTGCGG CATTAGATGCCAACATAGCTAGACTCCAGAAGTCTTTAAGGACTGGTCTTCTGGAGAAATGAATTCAGAAGAAAACTCATCAGGTGCTTC TTTTTAAAACTAGAACTTGGCTATATTGAATGTGTATTTTTCTTTAGTGAAATGATGTTTTATGTTATTATGTGTGAAGTAATATATTGT ACAAGTAATAAATGTATTGTTGAGATATATTGACACTGAGGAGCTTATAAAAACAAGTCATCTTAAGTTCACAATTGCTACAAGAAGAAA GTTGTGGATAACTAGGAAATTATTGTAAGTAATGTTTTATTTCAGTACTTAGCAATTAGAGTTCTTTTATTAAGATGTATCTGCTGGATT AAGGGTACAGGTTGAAATAGTTCTGTGGCTGTCCTAAGAAATAATGGGAAAAGAATCTCTGGATGTAAGTTTTTCTGTTGAAACTAGAGG GTTTTTTTTTTCTGTTTACATATACTTTTTTTTAATAGCAATGTGTTTTTATTAAACATGCTGTGTGCCACAGGCCAGTGTTGTTGGTGA AATATATAAACATTTATTTAAAGAGAAAAGTTACCAGTATCTACACCTCTTAAAAAACATTGATTGGTCTAAAAAATATATAGATAACAT CCTAAGTTAACATATGGCTTCTTAAAACTTGGGCACTTTTATTTGTTTTTATCCCAAATTCATGTTTTAAGGCCTTTAAAGAATAGTCAG ACTGATAAAGAAGTGCTAACAGATAAGCTATAGTTGGGGAAATTTGTGGGTTTTTTTTAAATAAGAAATGTTTATTTTTGTCCTTATATT TAAACATGATGGAATTTGTAAATCTTGGCATTGATTGTAATTCTGCCTTTTTGGAAGAATTTTTTCTCCCAGCATGTTAGCTGAGAATAT TCTCTATTTTATAAATAATATGAAGTAGGTTGGTCTCTCTGCTTCTCTATACCAGGACTTCTTAGCTCAGTATCATCTCCCTTCATGTAA GCAGCACGTTTTAACTCTTAGGAAGCTGAATGTTGTGTTATCACTAATACTTTGTACAGGTCACCTGCCTACTCTAATTGTCCTTAGTAC TTGGACAGGCTTTATCATTAAAGAGTGTTCTCCTAATCCCAGAACCTCCTCGTGTTTTTTGTTTTTTTGGTGGTTTTTTTTTTTTTTTTA GGTGTTAGTGCTACAGCGTTTGAAGGAGCCAGCTGTAGTCTCTTTGATATGTTCAGATTTTCCAGATAGAGATTTAAGTCTAAAAATTTA TTAAGTGAATTCTAAACTATTTCACACAAGAGTCCATTAGCATCTTTAATTTTATTTAGTATTCATGAATTAATTTATTGGCATCTTATT >85734_85734_10_SPG11-CCDC14_SPG11_chr15_44925703_ENST00000559193_CCDC14_chr3_123667979_ENST00000488653_length(amino acids)=1366AA_BP=579 MAAEEGVASAASAGGSWGTAAMGRVLPMLLVPVPAEAMGQLGSRAQLRTQPEALGSLTAAGSLQVLSLTPGSRGGGRCCLEGPFWHFLWE DSRNSSTPTEKPKLLALGENYELLIYEFNLKDGRCDATILYSCSREALQKLIDDQDISISLLSLRILSFHNNTSLLFINKCVILHIIFPE RDAAIRVLNCFTLPLPAQAVDMIIDTQLCRGILFVLSSLGWIYIFDVVDGTYVAHVDLALHKEDMCNEQQQEPAKISSFTSLKVSQDLDV AVIVSSSNSAVALNLNLYFRQHPGHLLCERILEDLPIQGPKGVDEDDPVNSAYNMKLAKFSFQIDRSWKAQLSSLNETIKNSKLEVSCCA PWFQDILHLESPESGNHSTSVQSWAFIPQDIMHGQYNVLQKDHAKTSDPGRSWKIMHISEQEEPIELKCVSVTGFTALFTWEVERMGYTI TLWDLETQGMQCFSLGTKCIPVDSSGDQQLCFVLTENGLSLILFGLTQEEFLNRLMIHGSASTVDTLCHLNGWGRCSIPIHALEAGIENR QLDTVNFFLKSKENLFNPSSKSSVSDQFDHLSSHLYLRTSSDNKKQIPNEASARSERDTSDLEQNWSLQDHYRMYSPIIYQALCEHVQTQ MSLMNDLTSKNIPNGIPAVPCHAPSHSESQATPHSSYGLCTSTPVWSLQRPPCPPKVHSEVQTDGNSQFASQGKTVSATCTDVLRNSFNT SPGVPCSLPKTDISAIPTLQQLGLVNGILPQQGIHKETDLLKCIQTYLSLFRSHGKETHLDSQTHRSPTQSQPAFLATNEEKCAREQIRE ATSERKDLNIHVRDTKTVKDVQKAKNVNKTAEKVRIIKYLLGELKALVAEQEDSEIQRLITEMEACISVLPTVSGNTDIQVEIALAMQPL RSENAQLRRQLRILNQQLREQQKTQKPSGAVDCNLELFSLQSLNMSLQNQLEESLKSQELLQSKNEELLKVIENQKDENKKFSSIFKDKD QTILENKQQYDIEITRIKIELEEALVNVKSSQFKLETAEKENQILGITLRQRDAEVTRLRELTRTLQTSMAKLLSDLSVDSARCKPGNNL TKSLLNIHDKQLQHDPAPAHTSIMSYLNKLETNYSFTHSEPLSTIKNEETIEPDKTYENVLSSRGPQNSNTRGMEEASAPGIISALSKQD SDEGSETMALIEDEHNLDNTIYIPFARSTPEKKSPLSKRLSPQPQIRAATTQLVSNSGLAVSGKENKLCTPVICSSSTKEAEDAPEKLSR ASDMKDTQLLKKIKEAIGKIPAATKEPEEQTACHGPSGCLSNSLQVKGNTVCDGSVFTSDLMSDWSISSFSTFTSRDEQDFRNGLAALDA -------------------------------------------------------------- |
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Fusion Gene PPI Analysis for SPG11-CCDC14 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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Related Drugs for SPG11-CCDC14 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.8 2021-05-08) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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Related Diseases for SPG11-CCDC14 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
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