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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:SPG11-TPCN1 (FusionGDB2 ID:85743)

Fusion Gene Summary for SPG11-TPCN1

check button Fusion gene summary
Fusion gene informationFusion gene name: SPG11-TPCN1
Fusion gene ID: 85743
HgeneTgene
Gene symbol

SPG11

TPCN1

Gene ID

80208

53373

Gene nameSPG11 vesicle trafficking associated, spatacsintwo pore segment channel 1
SynonymsALS5|CMT2X|KIAA1840TPC1
Cytomap

15q21.1

12q24.13

Type of geneprotein-codingprotein-coding
DescriptionspatacsinSPG11, spatacsin vesicle trafficking associatedamyotrophic lateral sclerosis 5colorectal carcinoma-associated proteinspastic paraplegia 11 (autosomal recessive)spastic paraplegia 11 proteintwo pore calcium channel protein 1two-pore channel 1, homologvoltage-dependent calcium channel protein TPC1
Modification date2020032920200313
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000261866, ENST00000427534, 
ENST00000535302, ENST00000558319, 
ENST00000559193, ENST00000558253, 
ENST00000546787, ENST00000335509, 
ENST00000392569, ENST00000541517, 
ENST00000550785, 
Fusion gene scores* DoF score11 X 11 X 7=8477 X 7 X 3=147
# samples 127
** MAII scorelog2(12/847*10)=-2.81932756372368
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(7/147*10)=-1.0703893278914
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: SPG11 [Title/Abstract] AND TPCN1 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointSPG11(44925703)-TPCN1(113723694), # samples:1
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
TgeneTPCN1

GO:0010508

positive regulation of autophagy

22012985


check buttonFusion gene breakpoints across SPG11 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across TPCN1 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4STADTCGA-BR-8080-01ASPG11chr15

44925703

-TPCN1chr12

113723694

+


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Fusion Gene ORF analysis for SPG11-TPCN1

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000261866ENST00000546787SPG11chr15

44925703

-TPCN1chr12

113723694

+
5CDS-intronENST00000427534ENST00000546787SPG11chr15

44925703

-TPCN1chr12

113723694

+
5CDS-intronENST00000535302ENST00000546787SPG11chr15

44925703

-TPCN1chr12

113723694

+
5CDS-intronENST00000558319ENST00000546787SPG11chr15

44925703

-TPCN1chr12

113723694

+
5CDS-intronENST00000559193ENST00000546787SPG11chr15

44925703

-TPCN1chr12

113723694

+
In-frameENST00000261866ENST00000335509SPG11chr15

44925703

-TPCN1chr12

113723694

+
In-frameENST00000261866ENST00000392569SPG11chr15

44925703

-TPCN1chr12

113723694

+
In-frameENST00000261866ENST00000541517SPG11chr15

44925703

-TPCN1chr12

113723694

+
In-frameENST00000261866ENST00000550785SPG11chr15

44925703

-TPCN1chr12

113723694

+
In-frameENST00000427534ENST00000335509SPG11chr15

44925703

-TPCN1chr12

113723694

+
In-frameENST00000427534ENST00000392569SPG11chr15

44925703

-TPCN1chr12

113723694

+
In-frameENST00000427534ENST00000541517SPG11chr15

44925703

-TPCN1chr12

113723694

+
In-frameENST00000427534ENST00000550785SPG11chr15

44925703

-TPCN1chr12

113723694

+
In-frameENST00000535302ENST00000335509SPG11chr15

44925703

-TPCN1chr12

113723694

+
In-frameENST00000535302ENST00000392569SPG11chr15

44925703

-TPCN1chr12

113723694

+
In-frameENST00000535302ENST00000541517SPG11chr15

44925703

-TPCN1chr12

113723694

+
In-frameENST00000535302ENST00000550785SPG11chr15

44925703

-TPCN1chr12

113723694

+
In-frameENST00000558319ENST00000335509SPG11chr15

44925703

-TPCN1chr12

113723694

+
In-frameENST00000558319ENST00000392569SPG11chr15

44925703

-TPCN1chr12

113723694

+
In-frameENST00000558319ENST00000541517SPG11chr15

44925703

-TPCN1chr12

113723694

+
In-frameENST00000558319ENST00000550785SPG11chr15

44925703

-TPCN1chr12

113723694

+
In-frameENST00000559193ENST00000335509SPG11chr15

44925703

-TPCN1chr12

113723694

+
In-frameENST00000559193ENST00000392569SPG11chr15

44925703

-TPCN1chr12

113723694

+
In-frameENST00000559193ENST00000541517SPG11chr15

44925703

-TPCN1chr12

113723694

+
In-frameENST00000559193ENST00000550785SPG11chr15

44925703

-TPCN1chr12

113723694

+
intron-3CDSENST00000558253ENST00000335509SPG11chr15

44925703

-TPCN1chr12

113723694

+
intron-3CDSENST00000558253ENST00000392569SPG11chr15

44925703

-TPCN1chr12

113723694

+
intron-3CDSENST00000558253ENST00000541517SPG11chr15

44925703

-TPCN1chr12

113723694

+
intron-3CDSENST00000558253ENST00000550785SPG11chr15

44925703

-TPCN1chr12

113723694

+
intron-intronENST00000558253ENST00000546787SPG11chr15

44925703

-TPCN1chr12

113723694

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000261866SPG11chr1544925703-ENST00000335509TPCN1chr12113723694+52591752172749910
ENST00000261866SPG11chr1544925703-ENST00000550785TPCN1chr12113723694+52591752172749910
ENST00000261866SPG11chr1544925703-ENST00000541517TPCN1chr12113723694+52561752172749910
ENST00000261866SPG11chr1544925703-ENST00000392569TPCN1chr12113723694+28681752172749910
ENST00000535302SPG11chr1544925703-ENST00000335509TPCN1chr12113723694+52701763282760910
ENST00000535302SPG11chr1544925703-ENST00000550785TPCN1chr12113723694+52701763282760910
ENST00000535302SPG11chr1544925703-ENST00000541517TPCN1chr12113723694+52671763282760910
ENST00000535302SPG11chr1544925703-ENST00000392569TPCN1chr12113723694+28791763282760910
ENST00000427534SPG11chr1544925703-ENST00000335509TPCN1chr12113723694+5242173502732910
ENST00000427534SPG11chr1544925703-ENST00000550785TPCN1chr12113723694+5242173502732910
ENST00000427534SPG11chr1544925703-ENST00000541517TPCN1chr12113723694+5239173502732910
ENST00000427534SPG11chr1544925703-ENST00000392569TPCN1chr12113723694+2851173502732910
ENST00000558319SPG11chr1544925703-ENST00000335509TPCN1chr12113723694+52731766312763910
ENST00000558319SPG11chr1544925703-ENST00000550785TPCN1chr12113723694+52731766312763910
ENST00000558319SPG11chr1544925703-ENST00000541517TPCN1chr12113723694+52701766312763910
ENST00000558319SPG11chr1544925703-ENST00000392569TPCN1chr12113723694+28821766312763910
ENST00000559193SPG11chr1544925703-ENST00000335509TPCN1chr12113723694+52531746112743910
ENST00000559193SPG11chr1544925703-ENST00000550785TPCN1chr12113723694+52531746112743910
ENST00000559193SPG11chr1544925703-ENST00000541517TPCN1chr12113723694+52501746112743910
ENST00000559193SPG11chr1544925703-ENST00000392569TPCN1chr12113723694+28621746112743910

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000261866ENST00000335509SPG11chr1544925703-TPCN1chr12113723694+0.0011751690.9988248
ENST00000261866ENST00000550785SPG11chr1544925703-TPCN1chr12113723694+0.0011751690.9988248
ENST00000261866ENST00000541517SPG11chr1544925703-TPCN1chr12113723694+0.0012015530.9987985
ENST00000261866ENST00000392569SPG11chr1544925703-TPCN1chr12113723694+0.00182290.99817705
ENST00000535302ENST00000335509SPG11chr1544925703-TPCN1chr12113723694+0.0011868310.99881315
ENST00000535302ENST00000550785SPG11chr1544925703-TPCN1chr12113723694+0.0011868310.99881315
ENST00000535302ENST00000541517SPG11chr1544925703-TPCN1chr12113723694+0.0012125590.99878746
ENST00000535302ENST00000392569SPG11chr1544925703-TPCN1chr12113723694+0.0018466980.99815327
ENST00000427534ENST00000335509SPG11chr1544925703-TPCN1chr12113723694+0.0011769920.998823
ENST00000427534ENST00000550785SPG11chr1544925703-TPCN1chr12113723694+0.0011769920.998823
ENST00000427534ENST00000541517SPG11chr1544925703-TPCN1chr12113723694+0.0012035070.99879646
ENST00000427534ENST00000392569SPG11chr1544925703-TPCN1chr12113723694+0.0018285370.99817145
ENST00000558319ENST00000335509SPG11chr1544925703-TPCN1chr12113723694+0.001180080.9988199
ENST00000558319ENST00000550785SPG11chr1544925703-TPCN1chr12113723694+0.001180080.9988199
ENST00000558319ENST00000541517SPG11chr1544925703-TPCN1chr12113723694+0.0012035170.99879646
ENST00000558319ENST00000392569SPG11chr1544925703-TPCN1chr12113723694+0.0018305430.9981694
ENST00000559193ENST00000335509SPG11chr1544925703-TPCN1chr12113723694+0.001201410.9987986
ENST00000559193ENST00000550785SPG11chr1544925703-TPCN1chr12113723694+0.001201410.9987986
ENST00000559193ENST00000541517SPG11chr1544925703-TPCN1chr12113723694+0.0012278090.9987722
ENST00000559193ENST00000392569SPG11chr1544925703-TPCN1chr12113723694+0.0018863930.99811363

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Fusion Genomic Features for SPG11-TPCN1


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
SPG11chr1544925702-TPCN1chr12113723693+0.0003168760.99968314
SPG11chr1544925702-TPCN1chr12113723693+0.0003168760.99968314

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for SPG11-TPCN1


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr15:44925703/chr12:113723694)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneTPCN1chr15:44925703chr12:113723694ENST000003355091628769_796484817.0Coiled coilOntology_term=ECO:0000255
TgeneTPCN1chr15:44925703chr12:113723694ENST000005415171628769_796556889.0Coiled coilOntology_term=ECO:0000255
TgeneTPCN1chr15:44925703chr12:113723694ENST000005507851729769_796556889.0Coiled coilOntology_term=ECO:0000255
TgeneTPCN1chr15:44925703chr12:113723694ENST000003355091628630_653484817.0IntramembraneHelical%3B Pore-forming
TgeneTPCN1chr15:44925703chr12:113723694ENST000005415171628630_653556889.0IntramembraneHelical%3B Pore-forming
TgeneTPCN1chr15:44925703chr12:113723694ENST000005507851729630_653556889.0IntramembraneHelical%3B Pore-forming
TgeneTPCN1chr15:44925703chr12:113723694ENST000003355091628501_503484817.0Topological domainCytoplasmic
TgeneTPCN1chr15:44925703chr12:113723694ENST000003355091628527_534484817.0Topological domainExtracellular
TgeneTPCN1chr15:44925703chr12:113723694ENST000003355091628550_573484817.0Topological domainCytoplasmic
TgeneTPCN1chr15:44925703chr12:113723694ENST000003355091628595_629484817.0Topological domainExtracellular
TgeneTPCN1chr15:44925703chr12:113723694ENST000003355091628654_670484817.0Topological domainExtracellular
TgeneTPCN1chr15:44925703chr12:113723694ENST000003355091628692_816484817.0Topological domainCytoplasmic
TgeneTPCN1chr15:44925703chr12:113723694ENST000005415171628595_629556889.0Topological domainExtracellular
TgeneTPCN1chr15:44925703chr12:113723694ENST000005415171628654_670556889.0Topological domainExtracellular
TgeneTPCN1chr15:44925703chr12:113723694ENST000005415171628692_816556889.0Topological domainCytoplasmic
TgeneTPCN1chr15:44925703chr12:113723694ENST000005507851729595_629556889.0Topological domainExtracellular
TgeneTPCN1chr15:44925703chr12:113723694ENST000005507851729654_670556889.0Topological domainExtracellular
TgeneTPCN1chr15:44925703chr12:113723694ENST000005507851729692_816556889.0Topological domainCytoplasmic
TgeneTPCN1chr15:44925703chr12:113723694ENST000003355091628504_526484817.0TransmembraneHelical%3B Name%3DS3 of repeat II
TgeneTPCN1chr15:44925703chr12:113723694ENST000003355091628535_549484817.0TransmembraneHelical%3B Name%3DS4 of repeat II
TgeneTPCN1chr15:44925703chr12:113723694ENST000003355091628574_594484817.0TransmembraneHelical%3B Name%3DS5 of repeat II
TgeneTPCN1chr15:44925703chr12:113723694ENST000003355091628671_691484817.0TransmembraneHelical%3B Name%3DS6 of repeat II
TgeneTPCN1chr15:44925703chr12:113723694ENST000005415171628574_594556889.0TransmembraneHelical%3B Name%3DS5 of repeat II
TgeneTPCN1chr15:44925703chr12:113723694ENST000005415171628671_691556889.0TransmembraneHelical%3B Name%3DS6 of repeat II
TgeneTPCN1chr15:44925703chr12:113723694ENST000005507851729574_594556889.0TransmembraneHelical%3B Name%3DS5 of repeat II
TgeneTPCN1chr15:44925703chr12:113723694ENST000005507851729671_691556889.0TransmembraneHelical%3B Name%3DS6 of repeat II

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneTPCN1chr15:44925703chr12:113723694ENST000003355091628263_286484817.0IntramembraneHelical%3B Pore-forming
TgeneTPCN1chr15:44925703chr12:113723694ENST000005415171628263_286556889.0IntramembraneHelical%3B Pore-forming
TgeneTPCN1chr15:44925703chr12:113723694ENST000005507851729263_286556889.0IntramembraneHelical%3B Pore-forming
TgeneTPCN1chr15:44925703chr12:113723694ENST000003355091628134_134484817.0Topological domainExtracellular
TgeneTPCN1chr15:44925703chr12:113723694ENST000003355091628156_177484817.0Topological domainCytoplasmic
TgeneTPCN1chr15:44925703chr12:113723694ENST000003355091628199_200484817.0Topological domainExtracellular
TgeneTPCN1chr15:44925703chr12:113723694ENST0000033550916281_112484817.0Topological domainCytoplasmic
TgeneTPCN1chr15:44925703chr12:113723694ENST000003355091628221_234484817.0Topological domainCytoplasmic
TgeneTPCN1chr15:44925703chr12:113723694ENST000003355091628256_262484817.0Topological domainExtracellular
TgeneTPCN1chr15:44925703chr12:113723694ENST000003355091628287_294484817.0Topological domainExtracellular
TgeneTPCN1chr15:44925703chr12:113723694ENST000003355091628316_444484817.0Topological domainCytoplasmic
TgeneTPCN1chr15:44925703chr12:113723694ENST000003355091628466_479484817.0Topological domainExtracellular
TgeneTPCN1chr15:44925703chr12:113723694ENST000005415171628134_134556889.0Topological domainExtracellular
TgeneTPCN1chr15:44925703chr12:113723694ENST000005415171628156_177556889.0Topological domainCytoplasmic
TgeneTPCN1chr15:44925703chr12:113723694ENST000005415171628199_200556889.0Topological domainExtracellular
TgeneTPCN1chr15:44925703chr12:113723694ENST0000054151716281_112556889.0Topological domainCytoplasmic
TgeneTPCN1chr15:44925703chr12:113723694ENST000005415171628221_234556889.0Topological domainCytoplasmic
TgeneTPCN1chr15:44925703chr12:113723694ENST000005415171628256_262556889.0Topological domainExtracellular
TgeneTPCN1chr15:44925703chr12:113723694ENST000005415171628287_294556889.0Topological domainExtracellular
TgeneTPCN1chr15:44925703chr12:113723694ENST000005415171628316_444556889.0Topological domainCytoplasmic
TgeneTPCN1chr15:44925703chr12:113723694ENST000005415171628466_479556889.0Topological domainExtracellular
TgeneTPCN1chr15:44925703chr12:113723694ENST000005415171628501_503556889.0Topological domainCytoplasmic
TgeneTPCN1chr15:44925703chr12:113723694ENST000005415171628527_534556889.0Topological domainExtracellular
TgeneTPCN1chr15:44925703chr12:113723694ENST000005415171628550_573556889.0Topological domainCytoplasmic
TgeneTPCN1chr15:44925703chr12:113723694ENST000005507851729134_134556889.0Topological domainExtracellular
TgeneTPCN1chr15:44925703chr12:113723694ENST000005507851729156_177556889.0Topological domainCytoplasmic
TgeneTPCN1chr15:44925703chr12:113723694ENST000005507851729199_200556889.0Topological domainExtracellular
TgeneTPCN1chr15:44925703chr12:113723694ENST0000055078517291_112556889.0Topological domainCytoplasmic
TgeneTPCN1chr15:44925703chr12:113723694ENST000005507851729221_234556889.0Topological domainCytoplasmic
TgeneTPCN1chr15:44925703chr12:113723694ENST000005507851729256_262556889.0Topological domainExtracellular
TgeneTPCN1chr15:44925703chr12:113723694ENST000005507851729287_294556889.0Topological domainExtracellular
TgeneTPCN1chr15:44925703chr12:113723694ENST000005507851729316_444556889.0Topological domainCytoplasmic
TgeneTPCN1chr15:44925703chr12:113723694ENST000005507851729466_479556889.0Topological domainExtracellular
TgeneTPCN1chr15:44925703chr12:113723694ENST000005507851729501_503556889.0Topological domainCytoplasmic
TgeneTPCN1chr15:44925703chr12:113723694ENST000005507851729527_534556889.0Topological domainExtracellular
TgeneTPCN1chr15:44925703chr12:113723694ENST000005507851729550_573556889.0Topological domainCytoplasmic
TgeneTPCN1chr15:44925703chr12:113723694ENST000003355091628113_133484817.0TransmembraneHelical%3B Name%3DS1 of repeat I
TgeneTPCN1chr15:44925703chr12:113723694ENST000003355091628135_155484817.0TransmembraneHelical%3B Name%3DS2 of repeat I
TgeneTPCN1chr15:44925703chr12:113723694ENST000003355091628178_198484817.0TransmembraneHelical%3B Name%3DS3 of repeat I
TgeneTPCN1chr15:44925703chr12:113723694ENST000003355091628201_220484817.0TransmembraneHelical%3B Name%3DS4 of repeat I
TgeneTPCN1chr15:44925703chr12:113723694ENST000003355091628235_255484817.0TransmembraneHelical%3B Name%3DS5 of repeat I
TgeneTPCN1chr15:44925703chr12:113723694ENST000003355091628295_315484817.0TransmembraneHelical%3B Name%3DS6 of repeat I
TgeneTPCN1chr15:44925703chr12:113723694ENST000003355091628445_465484817.0TransmembraneHelical%3B Name%3DS1 of repeat II
TgeneTPCN1chr15:44925703chr12:113723694ENST000003355091628480_500484817.0TransmembraneHelical%3B Name%3DS2 of repeat II
TgeneTPCN1chr15:44925703chr12:113723694ENST000005415171628113_133556889.0TransmembraneHelical%3B Name%3DS1 of repeat I
TgeneTPCN1chr15:44925703chr12:113723694ENST000005415171628135_155556889.0TransmembraneHelical%3B Name%3DS2 of repeat I
TgeneTPCN1chr15:44925703chr12:113723694ENST000005415171628178_198556889.0TransmembraneHelical%3B Name%3DS3 of repeat I
TgeneTPCN1chr15:44925703chr12:113723694ENST000005415171628201_220556889.0TransmembraneHelical%3B Name%3DS4 of repeat I
TgeneTPCN1chr15:44925703chr12:113723694ENST000005415171628235_255556889.0TransmembraneHelical%3B Name%3DS5 of repeat I
TgeneTPCN1chr15:44925703chr12:113723694ENST000005415171628295_315556889.0TransmembraneHelical%3B Name%3DS6 of repeat I
TgeneTPCN1chr15:44925703chr12:113723694ENST000005415171628445_465556889.0TransmembraneHelical%3B Name%3DS1 of repeat II
TgeneTPCN1chr15:44925703chr12:113723694ENST000005415171628480_500556889.0TransmembraneHelical%3B Name%3DS2 of repeat II
TgeneTPCN1chr15:44925703chr12:113723694ENST000005415171628504_526556889.0TransmembraneHelical%3B Name%3DS3 of repeat II
TgeneTPCN1chr15:44925703chr12:113723694ENST000005415171628535_549556889.0TransmembraneHelical%3B Name%3DS4 of repeat II
TgeneTPCN1chr15:44925703chr12:113723694ENST000005507851729113_133556889.0TransmembraneHelical%3B Name%3DS1 of repeat I
TgeneTPCN1chr15:44925703chr12:113723694ENST000005507851729135_155556889.0TransmembraneHelical%3B Name%3DS2 of repeat I
TgeneTPCN1chr15:44925703chr12:113723694ENST000005507851729178_198556889.0TransmembraneHelical%3B Name%3DS3 of repeat I
TgeneTPCN1chr15:44925703chr12:113723694ENST000005507851729201_220556889.0TransmembraneHelical%3B Name%3DS4 of repeat I
TgeneTPCN1chr15:44925703chr12:113723694ENST000005507851729235_255556889.0TransmembraneHelical%3B Name%3DS5 of repeat I
TgeneTPCN1chr15:44925703chr12:113723694ENST000005507851729295_315556889.0TransmembraneHelical%3B Name%3DS6 of repeat I
TgeneTPCN1chr15:44925703chr12:113723694ENST000005507851729445_465556889.0TransmembraneHelical%3B Name%3DS1 of repeat II
TgeneTPCN1chr15:44925703chr12:113723694ENST000005507851729480_500556889.0TransmembraneHelical%3B Name%3DS2 of repeat II
TgeneTPCN1chr15:44925703chr12:113723694ENST000005507851729504_526556889.0TransmembraneHelical%3B Name%3DS3 of repeat II
TgeneTPCN1chr15:44925703chr12:113723694ENST000005507851729535_549556889.0TransmembraneHelical%3B Name%3DS4 of repeat II


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Fusion Gene Sequence for SPG11-TPCN1


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>85743_85743_1_SPG11-TPCN1_SPG11_chr15_44925703_ENST00000261866_TPCN1_chr12_113723694_ENST00000335509_length(transcript)=5259nt_BP=1752nt
GTAACCGCCGGGCCAAGATGGCTGCAGAGGAAGGGGTCGCGAGTGCTGCTTCCGCCGGCGGTAGCTGGGGCACCGCGGCCATGGGGCGGG
TTCTACCGATGCTGTTGGTGCCAGTCCCCGCCGAGGCGATGGGGCAGCTCGGCTCCCGGGCGCAGCTGCGCACACAGCCGGAGGCTCTGG
GGAGCCTGACGGCTGCGGGCAGCCTCCAAGTGCTTTCTTTGACGCCTGGCAGCCGGGGCGGGGGTCGCTGCTGCCTGGAGGGCCCCTTCT
GGCACTTTCTATGGGAGGATTCTCGTAACAGCAGCACACCAACTGAAAAGCCCAAACTGCTCGCTCTTGGTGAAAATTATGAACTGCTTA
TCTATGAATTTAATTTGAAAGATGGAAGATGTGATGCAACCATTTTGTATAGCTGTAGTAGGGAGGCATTGCAAAAGCTCATTGACGATC
AAGATATCAGTATTTCCTTATTGTCTTTGAGAATCCTGTCATTTCACAATAACACATCATTACTGTTCATCAACAAATGTGTCATCCTAC
ATATTATATTTCCTGAAAGAGATGCTGCAATTAGAGTACTCAACTGTTTCACACTTCCCTTGCCTGCACAGGCAGTGGACATGATTATTG
ACACGCAGCTCTGCAGAGGAATTCTTTTTGTTTTGAGTAGTTTAGGCTGGATCTACATTTTTGATGTTGTGGATGGTACATATGTAGCTC
ATGTGGATTTAGCACTTCACAAAGAAGACATGTGTAATGAGCAGCAACAGGAGCCAGCCAAGATTTCTTCATTTACTTCACTGAAAGTTT
CTCAAGACCTCGATGTTGCAGTGATTGTCAGCTCCTCCAACTCCGCAGTTGCTCTTAACTTAAATTTGTATTTCAGGCAACACCCAGGAC
ACCTACTGTGTGAAAGAATACTAGAAGATCTTCCTATTCAAGGACCTAAGGGCGTAGATGAAGATGATCCTGTTAACTCTGCCTACAACA
TGAAACTGGCCAAGTTTTCCTTCCAAATTGATAGGTCTTGGAAAGCCCAGCTATCATCATTGAATGAAACAATAAAGAACTCCAAACTGG
AGGTTTCCTGTTGTGCTCCATGGTTCCAGGATATTTTGCATTTGGAGTCACCTGAATCTGGTAACCACAGTACAAGTGTGCAGAGCTGGG
CCTTCATTCCACAGGACATAATGCATGGGCAATATAATGTTCTACAGAAAGATCATGCCAAGACCAGTGATCCAGGAAGATCATGGAAAA
TAATGCACATCAGTGAACAAGAGGAACCCATAGAGCTTAAATGTGTGTCTGTGACAGGATTCACTGCACTGTTTACTTGGGAAGTGGAAA
GGATGGGCTATACCATTACCCTCTGGGATTTGGAGACCCAGGGCATGCAGTGTTTTTCCCTTGGCACAAAGTGTATTCCTGTAGACAGTA
GTGGAGACCAGCAGCTGTGCTTTGTTTTGACAGAGAATGGACTCTCTCTGATTTTGTTTGGTTTGACTCAAGAAGAGTTTTTAAACAGAC
TCATGATCCATGGAAGTGCCAGCACTGTGGACACTCTTTGTCATCTCAATGGCTGGGGAAGGTGCTCAATTCCCATACATGCACTAGAGG
CCGGGATAGAAAATCGTCAGCTGGACACAGTAAATTTCTTTTTGAAGAGCAAGGAAAATCTTTTTAATCCATCCTCAAAATCTTCTGTAT
CTGATCAGTTTGATCACTTGTCATCCCATTTATATTTAAGAATCTATGGGGTGGAGCTGTTCCTGAAGGTTGCCGGCCTGGGCCCTGTGG
AGTACTTGTCTTCCGGATGGAACTTGTTTGACTTCTCCGTGACAGTGTTCGCCTTCCTGGGACTGCTGGCGCTGGCCCTCAACATGGAGC
CCTTCTATTTCATCGTGGTCCTGCGCCCCCTCCAGCTGCTGAGGTTGTTTAAGTTGAAGGAGCGCTACCGCAACGTGCTGGACACCATGT
TCGAGCTGCTGCCCCGGATGGCCAGCCTGGGCCTCACCCTGCTCATCTTTTACTACTCCTTCGCCATCGTGGGCATGGAGTTCTTCTGCG
GGATCGTCTTCCCCAACTGCTGCAACACGAGTACAGTGGCAGATGCCTACCGCTGGCGCAACCACACCGTGGGCAACAGGACCGTGGTGG
AGGAAGGCTACTATTATCTCAATAATTTTGACAACATCCTCAACAGCTTTGTGACCCTGTTTGAGCTCACAGTTGTCAACAACTGGTACA
TCATCATGGAAGGCGTCACCTCTCAGACCTCCCACTGGAGCCGCCTCTACTTCATGACCTTTTACATTGTGACCATGGTGGTGATGACGA
TCATTGTCGCCTTTATCCTCGAGGCCTTCGTCTTCCGAATGAACTACAGCCGCAAGAACCAGGACTCGGAAGTTGATGGTGGCATCACCC
TTGAGAAGGAAATCTCCAAAGAAGAGCTGGTTGCCGTCCTGGAGCTCTACCGGGAGGCACGGGGGGCCTCCTCGGATGTCACCAGGCTGC
TGGAGACCCTCTCCCAGATGGAGAGATACCAGCAACATTCCATGGTGTTTCTGGGACGGCGATCAAGGACCAAGAGCGACCTGAGCCTGA
AGATGTACCAGGAGGAGATCCAGGAGTGGTATGAGGAGCATGCCAGGGAGCAAGAGCAGCAGCGACAACTCAGCAGCAGTGCAGCCCCCG
CCGCCCAGCAGCCCCCAGGCAGCCGCCAGCGCTCCCAGACCGTTACCTAGCCCAGCGCCCGAAAGCCGTCTCTTCTATGCAATAACACAA
TAGTATTACTCTACTGCGATGTACGGAACTGCGGTGTGTGTACACATACTCACGTATATGCACATATTTATATACAGGAAGAAAAAAGAC
AGACAAGATGGGGCTTGGTTTATAACCACCTTGCCCTGTCTTCCTTAACTCCAGAAGCCAGTTTGGTGAGGGGTGGGGGTGCGGCCACCA
GGTCTGAGCTCTTCCTACTGTGGAAGGCTCCAGAAGGCCCTTCACAAGGAGACCCCTCACCTGGATCCAGTCGACTGCGGGGCTTGCCCC
TCATGTGGGCTGGCCTCCATCGGCCACGTCCAAAGCTGTCACTGCTACTGCTTCAGGCTCACATCCCCCCGACCTGATGGCGTGCCCGCC
CCCTCTCCCTGCGGCCCATGCCACAGGTTTCTGTGTTTTGCTTTAGGGACAGAACCACTTAGGAAGGAAAGAACTCCCGGTCTCCAGGGT
GGTATTTCAGTGTCTGTGATAATGTCACGCAACACCTCTTCGGGGACCAGTGCCCAGGATCTAATGGAAGCGGAATTGGGGCAACTGGGC
CCATGTGGCCAGAGCTCAGTTAGCCAGTGCCGGGCGGCCACAGATTACACTGACCAATCTCCTCCCTTGGCTCTGCAAGCCTCCCACCCA
GCCTTCTCTGGCTTAACCCTTGTTGGCGAAAACTCTTCCACAGTGGCCTCCTTGGGGACCCAGAACCCGGAGGAAGGGGCATGAGGCAGG
AAGTGGGGCCGATGTCTGCAACCCAGACCACTTCGTGGAATGGGCTCTTGACCAAATCCCTTTTTTTGCGATTTACCCGTTCAAGCAAAA
CAACGTTTTGGTTAACTAAGGATTGTGCTAAAGCCGATACCAGGTCCTTCACACGTGTGCACTAGGAACAGGAGCGAACAGCACAGAGAG
ACGCTCCCTGTGGGACGCAGCAGCCCCGTGGCCCCGGCCCAGTTCCCAGCCACCCTCCCTGGCTCTGCTCACACCAGAGATTTCCATAGC
AGGAGCGGTTGGTGCAGAAGTAGGTTCAGATGAACCTCAGTTAACGTCGCCACCCCTCCTCCCACCATGGTACCCTGTAGGAGCCCTGTA
TGACATCTGAGCGTGGTGGAGGTAGGAGGGTTGCCAGCTGCAGTGACCCTGCCACAGAGGCAGGGTCAGTGCAGAGGTCGCTTTGGTTCC
GCTTCCCTGGGCCACAGAACGGAACACAGCATAGGTTCTGCAGCAGGAGCCGCAGTGGCAGGATGGAGGGTGCGAAGGGCAAGGAGTGCA
CTGCTGGGCATTCCTGGCCAGCCCCGGCCCTCTGGTGCCTGCTTCCTGTGACTTCAGAAGGCAGGTGGACAGAGCCTCCCTCTGGCCTTG
TCCTCTTCCCAGCCACAGAACGGGCAGGGTGGCACCCGACCCCAGGGGAGCAGTACCTGGTCCCCCACCCCCTCCTCCCAACCACCTCCA
AGGCCAAGCTGGGTCCCATAGCCAGCACGGCATGGTTCTCCCCTTCCCCCCTTCCCAGGTCAGGGGAGTTGGACAAGTAGCAGGTGTTTG
TTTTTAAAGCACAGCCCTTTGGGAAAGCAACACATTATTGAGACTCACTGTGATTCCCCCGGGAGTCAGACTGGCTTTGTCCTCTTCCTC
TCTGGAGGGCCATGGGCCATCAGCAGGAGCTCCACATCGAGCCCCAGGCCAGAACCCCCTCCCTTTCACAGAGAGGGAACTTTATTGCAC
AATTGGGTGCCTTTTAGCTTTTGTGTGTTGAAATGGGCGTTTTGGAAGCAAGGGTCAGGGGACAGCTTCTAAAGGTGTGAGTCTCTGACC
TGAGCATCTGGGCCTCGCCTGGGCCCTTCTTCCTCCCCAGGGGTGGAAACGTGGAGGGGCCAGCAGCACCCCGGGGTCTGCCCAGGGGAG
TCAAGGCCCCGAGGTGGGGGGGCCTATTCCAGGAGGAGTGGGATCTCGGCCCTGTCCAGAGCGAGTTAATGTGTCCATCTGCCCAACCCT
GTCCTGAGAAAGGACCTGGTTTTGGCCAGGACCTGACAAATACCCAATGGCAGCAGTGTCAACAGACGGGAGTCCAGCCAGGGTGGGTGC
CCTTGTCATTGAGGTTAGGGACAGCTATCCCCAGGTTATGCCTGGCCCCACCCAGCAGGGAGTTGGGGTCCCCCCACAGGCTGTGAGCTC
TGTGGGCCCTGGGATGTGATCTAGCTCAGATGCCCTCTCATCCTTGATGTCATAGTTGAGTGCACCCAAGTGGCACCCACTGGCGGCCAG
GGGCACAGCCTGGTGGTGGTGGCAATAGAACTGTGCCCCTCCTCAGCTCCTCGCTTCCCCTCCCACAGCCCCAGCCTTACTCCACCATGC
GGACAATCATTTTGTACGGATCACGGGAGCAATGCTGTACGGTTTTGTACACTGGTGGTTTGTTTCCTAGAAAACCCATTGTGTCTCTGG

>85743_85743_1_SPG11-TPCN1_SPG11_chr15_44925703_ENST00000261866_TPCN1_chr12_113723694_ENST00000335509_length(amino acids)=910AA_BP=579
MAAEEGVASAASAGGSWGTAAMGRVLPMLLVPVPAEAMGQLGSRAQLRTQPEALGSLTAAGSLQVLSLTPGSRGGGRCCLEGPFWHFLWE
DSRNSSTPTEKPKLLALGENYELLIYEFNLKDGRCDATILYSCSREALQKLIDDQDISISLLSLRILSFHNNTSLLFINKCVILHIIFPE
RDAAIRVLNCFTLPLPAQAVDMIIDTQLCRGILFVLSSLGWIYIFDVVDGTYVAHVDLALHKEDMCNEQQQEPAKISSFTSLKVSQDLDV
AVIVSSSNSAVALNLNLYFRQHPGHLLCERILEDLPIQGPKGVDEDDPVNSAYNMKLAKFSFQIDRSWKAQLSSLNETIKNSKLEVSCCA
PWFQDILHLESPESGNHSTSVQSWAFIPQDIMHGQYNVLQKDHAKTSDPGRSWKIMHISEQEEPIELKCVSVTGFTALFTWEVERMGYTI
TLWDLETQGMQCFSLGTKCIPVDSSGDQQLCFVLTENGLSLILFGLTQEEFLNRLMIHGSASTVDTLCHLNGWGRCSIPIHALEAGIENR
QLDTVNFFLKSKENLFNPSSKSSVSDQFDHLSSHLYLRIYGVELFLKVAGLGPVEYLSSGWNLFDFSVTVFAFLGLLALALNMEPFYFIV
VLRPLQLLRLFKLKERYRNVLDTMFELLPRMASLGLTLLIFYYSFAIVGMEFFCGIVFPNCCNTSTVADAYRWRNHTVGNRTVVEEGYYY
LNNFDNILNSFVTLFELTVVNNWYIIMEGVTSQTSHWSRLYFMTFYIVTMVVMTIIVAFILEAFVFRMNYSRKNQDSEVDGGITLEKEIS
KEELVAVLELYREARGASSDVTRLLETLSQMERYQQHSMVFLGRRSRTKSDLSLKMYQEEIQEWYEEHAREQEQQRQLSSSAAPAAQQPP

--------------------------------------------------------------
>85743_85743_2_SPG11-TPCN1_SPG11_chr15_44925703_ENST00000261866_TPCN1_chr12_113723694_ENST00000392569_length(transcript)=2868nt_BP=1752nt
GTAACCGCCGGGCCAAGATGGCTGCAGAGGAAGGGGTCGCGAGTGCTGCTTCCGCCGGCGGTAGCTGGGGCACCGCGGCCATGGGGCGGG
TTCTACCGATGCTGTTGGTGCCAGTCCCCGCCGAGGCGATGGGGCAGCTCGGCTCCCGGGCGCAGCTGCGCACACAGCCGGAGGCTCTGG
GGAGCCTGACGGCTGCGGGCAGCCTCCAAGTGCTTTCTTTGACGCCTGGCAGCCGGGGCGGGGGTCGCTGCTGCCTGGAGGGCCCCTTCT
GGCACTTTCTATGGGAGGATTCTCGTAACAGCAGCACACCAACTGAAAAGCCCAAACTGCTCGCTCTTGGTGAAAATTATGAACTGCTTA
TCTATGAATTTAATTTGAAAGATGGAAGATGTGATGCAACCATTTTGTATAGCTGTAGTAGGGAGGCATTGCAAAAGCTCATTGACGATC
AAGATATCAGTATTTCCTTATTGTCTTTGAGAATCCTGTCATTTCACAATAACACATCATTACTGTTCATCAACAAATGTGTCATCCTAC
ATATTATATTTCCTGAAAGAGATGCTGCAATTAGAGTACTCAACTGTTTCACACTTCCCTTGCCTGCACAGGCAGTGGACATGATTATTG
ACACGCAGCTCTGCAGAGGAATTCTTTTTGTTTTGAGTAGTTTAGGCTGGATCTACATTTTTGATGTTGTGGATGGTACATATGTAGCTC
ATGTGGATTTAGCACTTCACAAAGAAGACATGTGTAATGAGCAGCAACAGGAGCCAGCCAAGATTTCTTCATTTACTTCACTGAAAGTTT
CTCAAGACCTCGATGTTGCAGTGATTGTCAGCTCCTCCAACTCCGCAGTTGCTCTTAACTTAAATTTGTATTTCAGGCAACACCCAGGAC
ACCTACTGTGTGAAAGAATACTAGAAGATCTTCCTATTCAAGGACCTAAGGGCGTAGATGAAGATGATCCTGTTAACTCTGCCTACAACA
TGAAACTGGCCAAGTTTTCCTTCCAAATTGATAGGTCTTGGAAAGCCCAGCTATCATCATTGAATGAAACAATAAAGAACTCCAAACTGG
AGGTTTCCTGTTGTGCTCCATGGTTCCAGGATATTTTGCATTTGGAGTCACCTGAATCTGGTAACCACAGTACAAGTGTGCAGAGCTGGG
CCTTCATTCCACAGGACATAATGCATGGGCAATATAATGTTCTACAGAAAGATCATGCCAAGACCAGTGATCCAGGAAGATCATGGAAAA
TAATGCACATCAGTGAACAAGAGGAACCCATAGAGCTTAAATGTGTGTCTGTGACAGGATTCACTGCACTGTTTACTTGGGAAGTGGAAA
GGATGGGCTATACCATTACCCTCTGGGATTTGGAGACCCAGGGCATGCAGTGTTTTTCCCTTGGCACAAAGTGTATTCCTGTAGACAGTA
GTGGAGACCAGCAGCTGTGCTTTGTTTTGACAGAGAATGGACTCTCTCTGATTTTGTTTGGTTTGACTCAAGAAGAGTTTTTAAACAGAC
TCATGATCCATGGAAGTGCCAGCACTGTGGACACTCTTTGTCATCTCAATGGCTGGGGAAGGTGCTCAATTCCCATACATGCACTAGAGG
CCGGGATAGAAAATCGTCAGCTGGACACAGTAAATTTCTTTTTGAAGAGCAAGGAAAATCTTTTTAATCCATCCTCAAAATCTTCTGTAT
CTGATCAGTTTGATCACTTGTCATCCCATTTATATTTAAGAATCTATGGGGTGGAGCTGTTCCTGAAGGTTGCCGGCCTGGGCCCTGTGG
AGTACTTGTCTTCCGGATGGAACTTGTTTGACTTCTCCGTGACAGTGTTCGCCTTCCTGGGACTGCTGGCGCTGGCCCTCAACATGGAGC
CCTTCTATTTCATCGTGGTCCTGCGCCCCCTCCAGCTGCTGAGGTTGTTTAAGTTGAAGGAGCGCTACCGCAACGTGCTGGACACCATGT
TCGAGCTGCTGCCCCGGATGGCCAGCCTGGGCCTCACCCTGCTCATCTTTTACTACTCCTTCGCCATCGTGGGCATGGAGTTCTTCTGCG
GGATCGTCTTCCCCAACTGCTGCAACACGAGTACAGTGGCAGATGCCTACCGCTGGCGCAACCACACCGTGGGCAACAGGACCGTGGTGG
AGGAAGGCTACTATTATCTCAATAATTTTGACAACATCCTCAACAGCTTTGTGACCCTGTTTGAGCTCACAGTTGTCAACAACTGGTACA
TCATCATGGAAGGCGTCACCTCTCAGACCTCCCACTGGAGCCGCCTCTACTTCATGACCTTTTACATTGTGACCATGGTGGTGATGACGA
TCATTGTCGCCTTTATCCTCGAGGCCTTCGTCTTCCGAATGAACTACAGCCGCAAGAACCAGGACTCGGAAGTTGATGGTGGCATCACCC
TTGAGAAGGAAATCTCCAAAGAAGAGCTGGTTGCCGTCCTGGAGCTCTACCGGGAGGCACGGGGGGCCTCCTCGGATGTCACCAGGCTGC
TGGAGACCCTCTCCCAGATGGAGAGATACCAGCAACATTCCATGGTGTTTCTGGGACGGCGATCAAGGACCAAGAGCGACCTGAGCCTGA
AGATGTACCAGGAGGAGATCCAGGAGTGGTATGAGGAGCATGCCAGGGAGCAAGAGCAGCAGCGACAACTCAGCAGCAGTGCAGCCCCCG
CCGCCCAGCAGCCCCCAGGCAGCCGCCAGCGCTCCCAGACCGTTACCTAGCCCAGCGCCCGAAAGCCGTCTCTTCTATGCAATAACACAA

>85743_85743_2_SPG11-TPCN1_SPG11_chr15_44925703_ENST00000261866_TPCN1_chr12_113723694_ENST00000392569_length(amino acids)=910AA_BP=579
MAAEEGVASAASAGGSWGTAAMGRVLPMLLVPVPAEAMGQLGSRAQLRTQPEALGSLTAAGSLQVLSLTPGSRGGGRCCLEGPFWHFLWE
DSRNSSTPTEKPKLLALGENYELLIYEFNLKDGRCDATILYSCSREALQKLIDDQDISISLLSLRILSFHNNTSLLFINKCVILHIIFPE
RDAAIRVLNCFTLPLPAQAVDMIIDTQLCRGILFVLSSLGWIYIFDVVDGTYVAHVDLALHKEDMCNEQQQEPAKISSFTSLKVSQDLDV
AVIVSSSNSAVALNLNLYFRQHPGHLLCERILEDLPIQGPKGVDEDDPVNSAYNMKLAKFSFQIDRSWKAQLSSLNETIKNSKLEVSCCA
PWFQDILHLESPESGNHSTSVQSWAFIPQDIMHGQYNVLQKDHAKTSDPGRSWKIMHISEQEEPIELKCVSVTGFTALFTWEVERMGYTI
TLWDLETQGMQCFSLGTKCIPVDSSGDQQLCFVLTENGLSLILFGLTQEEFLNRLMIHGSASTVDTLCHLNGWGRCSIPIHALEAGIENR
QLDTVNFFLKSKENLFNPSSKSSVSDQFDHLSSHLYLRIYGVELFLKVAGLGPVEYLSSGWNLFDFSVTVFAFLGLLALALNMEPFYFIV
VLRPLQLLRLFKLKERYRNVLDTMFELLPRMASLGLTLLIFYYSFAIVGMEFFCGIVFPNCCNTSTVADAYRWRNHTVGNRTVVEEGYYY
LNNFDNILNSFVTLFELTVVNNWYIIMEGVTSQTSHWSRLYFMTFYIVTMVVMTIIVAFILEAFVFRMNYSRKNQDSEVDGGITLEKEIS
KEELVAVLELYREARGASSDVTRLLETLSQMERYQQHSMVFLGRRSRTKSDLSLKMYQEEIQEWYEEHAREQEQQRQLSSSAAPAAQQPP

--------------------------------------------------------------
>85743_85743_3_SPG11-TPCN1_SPG11_chr15_44925703_ENST00000261866_TPCN1_chr12_113723694_ENST00000541517_length(transcript)=5256nt_BP=1752nt
GTAACCGCCGGGCCAAGATGGCTGCAGAGGAAGGGGTCGCGAGTGCTGCTTCCGCCGGCGGTAGCTGGGGCACCGCGGCCATGGGGCGGG
TTCTACCGATGCTGTTGGTGCCAGTCCCCGCCGAGGCGATGGGGCAGCTCGGCTCCCGGGCGCAGCTGCGCACACAGCCGGAGGCTCTGG
GGAGCCTGACGGCTGCGGGCAGCCTCCAAGTGCTTTCTTTGACGCCTGGCAGCCGGGGCGGGGGTCGCTGCTGCCTGGAGGGCCCCTTCT
GGCACTTTCTATGGGAGGATTCTCGTAACAGCAGCACACCAACTGAAAAGCCCAAACTGCTCGCTCTTGGTGAAAATTATGAACTGCTTA
TCTATGAATTTAATTTGAAAGATGGAAGATGTGATGCAACCATTTTGTATAGCTGTAGTAGGGAGGCATTGCAAAAGCTCATTGACGATC
AAGATATCAGTATTTCCTTATTGTCTTTGAGAATCCTGTCATTTCACAATAACACATCATTACTGTTCATCAACAAATGTGTCATCCTAC
ATATTATATTTCCTGAAAGAGATGCTGCAATTAGAGTACTCAACTGTTTCACACTTCCCTTGCCTGCACAGGCAGTGGACATGATTATTG
ACACGCAGCTCTGCAGAGGAATTCTTTTTGTTTTGAGTAGTTTAGGCTGGATCTACATTTTTGATGTTGTGGATGGTACATATGTAGCTC
ATGTGGATTTAGCACTTCACAAAGAAGACATGTGTAATGAGCAGCAACAGGAGCCAGCCAAGATTTCTTCATTTACTTCACTGAAAGTTT
CTCAAGACCTCGATGTTGCAGTGATTGTCAGCTCCTCCAACTCCGCAGTTGCTCTTAACTTAAATTTGTATTTCAGGCAACACCCAGGAC
ACCTACTGTGTGAAAGAATACTAGAAGATCTTCCTATTCAAGGACCTAAGGGCGTAGATGAAGATGATCCTGTTAACTCTGCCTACAACA
TGAAACTGGCCAAGTTTTCCTTCCAAATTGATAGGTCTTGGAAAGCCCAGCTATCATCATTGAATGAAACAATAAAGAACTCCAAACTGG
AGGTTTCCTGTTGTGCTCCATGGTTCCAGGATATTTTGCATTTGGAGTCACCTGAATCTGGTAACCACAGTACAAGTGTGCAGAGCTGGG
CCTTCATTCCACAGGACATAATGCATGGGCAATATAATGTTCTACAGAAAGATCATGCCAAGACCAGTGATCCAGGAAGATCATGGAAAA
TAATGCACATCAGTGAACAAGAGGAACCCATAGAGCTTAAATGTGTGTCTGTGACAGGATTCACTGCACTGTTTACTTGGGAAGTGGAAA
GGATGGGCTATACCATTACCCTCTGGGATTTGGAGACCCAGGGCATGCAGTGTTTTTCCCTTGGCACAAAGTGTATTCCTGTAGACAGTA
GTGGAGACCAGCAGCTGTGCTTTGTTTTGACAGAGAATGGACTCTCTCTGATTTTGTTTGGTTTGACTCAAGAAGAGTTTTTAAACAGAC
TCATGATCCATGGAAGTGCCAGCACTGTGGACACTCTTTGTCATCTCAATGGCTGGGGAAGGTGCTCAATTCCCATACATGCACTAGAGG
CCGGGATAGAAAATCGTCAGCTGGACACAGTAAATTTCTTTTTGAAGAGCAAGGAAAATCTTTTTAATCCATCCTCAAAATCTTCTGTAT
CTGATCAGTTTGATCACTTGTCATCCCATTTATATTTAAGAATCTATGGGGTGGAGCTGTTCCTGAAGGTTGCCGGCCTGGGCCCTGTGG
AGTACTTGTCTTCCGGATGGAACTTGTTTGACTTCTCCGTGACAGTGTTCGCCTTCCTGGGACTGCTGGCGCTGGCCCTCAACATGGAGC
CCTTCTATTTCATCGTGGTCCTGCGCCCCCTCCAGCTGCTGAGGTTGTTTAAGTTGAAGGAGCGCTACCGCAACGTGCTGGACACCATGT
TCGAGCTGCTGCCCCGGATGGCCAGCCTGGGCCTCACCCTGCTCATCTTTTACTACTCCTTCGCCATCGTGGGCATGGAGTTCTTCTGCG
GGATCGTCTTCCCCAACTGCTGCAACACGAGTACAGTGGCAGATGCCTACCGCTGGCGCAACCACACCGTGGGCAACAGGACCGTGGTGG
AGGAAGGCTACTATTATCTCAATAATTTTGACAACATCCTCAACAGCTTTGTGACCCTGTTTGAGCTCACAGTTGTCAACAACTGGTACA
TCATCATGGAAGGCGTCACCTCTCAGACCTCCCACTGGAGCCGCCTCTACTTCATGACCTTTTACATTGTGACCATGGTGGTGATGACGA
TCATTGTCGCCTTTATCCTCGAGGCCTTCGTCTTCCGAATGAACTACAGCCGCAAGAACCAGGACTCGGAAGTTGATGGTGGCATCACCC
TTGAGAAGGAAATCTCCAAAGAAGAGCTGGTTGCCGTCCTGGAGCTCTACCGGGAGGCACGGGGGGCCTCCTCGGATGTCACCAGGCTGC
TGGAGACCCTCTCCCAGATGGAGAGATACCAGCAACATTCCATGGTGTTTCTGGGACGGCGATCAAGGACCAAGAGCGACCTGAGCCTGA
AGATGTACCAGGAGGAGATCCAGGAGTGGTATGAGGAGCATGCCAGGGAGCAAGAGCAGCAGCGACAACTCAGCAGCAGTGCAGCCCCCG
CCGCCCAGCAGCCCCCAGGCAGCCGCCAGCGCTCCCAGACCGTTACCTAGCCCAGCGCCCGAAAGCCGTCTCTTCTATGCAATAACACAA
TAGTATTACTCTACTGCGATGTACGGAACTGCGGTGTGTGTACACATACTCACGTATATGCACATATTTATATACAGGAAGAAAAAAGAC
AGACAAGATGGGGCTTGGTTTATAACCACCTTGCCCTGTCTTCCTTAACTCCAGAAGCCAGTTTGGTGAGGGGTGGGGGTGCGGCCACCA
GGTCTGAGCTCTTCCTACTGTGGAAGGCTCCAGAAGGCCCTTCACAAGGAGACCCCTCACCTGGATCCAGTCGACTGCGGGGCTTGCCCC
TCATGTGGGCTGGCCTCCATCGGCCACGTCCAAAGCTGTCACTGCTACTGCTTCAGGCTCACATCCCCCCGACCTGATGGCGTGCCCGCC
CCCTCTCCCTGCGGCCCATGCCACAGGTTTCTGTGTTTTGCTTTAGGGACAGAACCACTTAGGAAGGAAAGAACTCCCGGTCTCCAGGGT
GGTATTTCAGTGTCTGTGATAATGTCACGCAACACCTCTTCGGGGACCAGTGCCCAGGATCTAATGGAAGCGGAATTGGGGCAACTGGGC
CCATGTGGCCAGAGCTCAGTTAGCCAGTGCCGGGCGGCCACAGATTACACTGACCAATCTCCTCCCTTGGCTCTGCAAGCCTCCCACCCA
GCCTTCTCTGGCTTAACCCTTGTTGGCGAAAACTCTTCCACAGTGGCCTCCTTGGGGACCCAGAACCCGGAGGAAGGGGCATGAGGCAGG
AAGTGGGGCCGATGTCTGCAACCCAGACCACTTCGTGGAATGGGCTCTTGACCAAATCCCTTTTTTTGCGATTTACCCGTTCAAGCAAAA
CAACGTTTTGGTTAACTAAGGATTGTGCTAAAGCCGATACCAGGTCCTTCACACGTGTGCACTAGGAACAGGAGCGAACAGCACAGAGAG
ACGCTCCCTGTGGGACGCAGCAGCCCCGTGGCCCCGGCCCAGTTCCCAGCCACCCTCCCTGGCTCTGCTCACACCAGAGATTTCCATAGC
AGGAGCGGTTGGTGCAGAAGTAGGTTCAGATGAACCTCAGTTAACGTCGCCACCCCTCCTCCCACCATGGTACCCTGTAGGAGCCCTGTA
TGACATCTGAGCGTGGTGGAGGTAGGAGGGTTGCCAGCTGCAGTGACCCTGCCACAGAGGCAGGGTCAGTGCAGAGGTCGCTTTGGTTCC
GCTTCCCTGGGCCACAGAACGGAACACAGCATAGGTTCTGCAGCAGGAGCCGCAGTGGCAGGATGGAGGGTGCGAAGGGCAAGGAGTGCA
CTGCTGGGCATTCCTGGCCAGCCCCGGCCCTCTGGTGCCTGCTTCCTGTGACTTCAGAAGGCAGGTGGACAGAGCCTCCCTCTGGCCTTG
TCCTCTTCCCAGCCACAGAACGGGCAGGGTGGCACCCGACCCCAGGGGAGCAGTACCTGGTCCCCCACCCCCTCCTCCCAACCACCTCCA
AGGCCAAGCTGGGTCCCATAGCCAGCACGGCATGGTTCTCCCCTTCCCCCCTTCCCAGGTCAGGGGAGTTGGACAAGTAGCAGGTGTTTG
TTTTTAAAGCACAGCCCTTTGGGAAAGCAACACATTATTGAGACTCACTGTGATTCCCCCGGGAGTCAGACTGGCTTTGTCCTCTTCCTC
TCTGGAGGGCCATGGGCCATCAGCAGGAGCTCCACATCGAGCCCCAGGCCAGAACCCCCTCCCTTTCACAGAGAGGGAACTTTATTGCAC
AATTGGGTGCCTTTTAGCTTTTGTGTGTTGAAATGGGCGTTTTGGAAGCAAGGGTCAGGGGACAGCTTCTAAAGGTGTGAGTCTCTGACC
TGAGCATCTGGGCCTCGCCTGGGCCCTTCTTCCTCCCCAGGGGTGGAAACGTGGAGGGGCCAGCAGCACCCCGGGGTCTGCCCAGGGGAG
TCAAGGCCCCGAGGTGGGGGGGCCTATTCCAGGAGGAGTGGGATCTCGGCCCTGTCCAGAGCGAGTTAATGTGTCCATCTGCCCAACCCT
GTCCTGAGAAAGGACCTGGTTTTGGCCAGGACCTGACAAATACCCAATGGCAGCAGTGTCAACAGACGGGAGTCCAGCCAGGGTGGGTGC
CCTTGTCATTGAGGTTAGGGACAGCTATCCCCAGGTTATGCCTGGCCCCACCCAGCAGGGAGTTGGGGTCCCCCCACAGGCTGTGAGCTC
TGTGGGCCCTGGGATGTGATCTAGCTCAGATGCCCTCTCATCCTTGATGTCATAGTTGAGTGCACCCAAGTGGCACCCACTGGCGGCCAG
GGGCACAGCCTGGTGGTGGTGGCAATAGAACTGTGCCCCTCCTCAGCTCCTCGCTTCCCCTCCCACAGCCCCAGCCTTACTCCACCATGC
GGACAATCATTTTGTACGGATCACGGGAGCAATGCTGTACGGTTTTGTACACTGGTGGTTTGTTTCCTAGAAAACCCATTGTGTCTCTGG

>85743_85743_3_SPG11-TPCN1_SPG11_chr15_44925703_ENST00000261866_TPCN1_chr12_113723694_ENST00000541517_length(amino acids)=910AA_BP=579
MAAEEGVASAASAGGSWGTAAMGRVLPMLLVPVPAEAMGQLGSRAQLRTQPEALGSLTAAGSLQVLSLTPGSRGGGRCCLEGPFWHFLWE
DSRNSSTPTEKPKLLALGENYELLIYEFNLKDGRCDATILYSCSREALQKLIDDQDISISLLSLRILSFHNNTSLLFINKCVILHIIFPE
RDAAIRVLNCFTLPLPAQAVDMIIDTQLCRGILFVLSSLGWIYIFDVVDGTYVAHVDLALHKEDMCNEQQQEPAKISSFTSLKVSQDLDV
AVIVSSSNSAVALNLNLYFRQHPGHLLCERILEDLPIQGPKGVDEDDPVNSAYNMKLAKFSFQIDRSWKAQLSSLNETIKNSKLEVSCCA
PWFQDILHLESPESGNHSTSVQSWAFIPQDIMHGQYNVLQKDHAKTSDPGRSWKIMHISEQEEPIELKCVSVTGFTALFTWEVERMGYTI
TLWDLETQGMQCFSLGTKCIPVDSSGDQQLCFVLTENGLSLILFGLTQEEFLNRLMIHGSASTVDTLCHLNGWGRCSIPIHALEAGIENR
QLDTVNFFLKSKENLFNPSSKSSVSDQFDHLSSHLYLRIYGVELFLKVAGLGPVEYLSSGWNLFDFSVTVFAFLGLLALALNMEPFYFIV
VLRPLQLLRLFKLKERYRNVLDTMFELLPRMASLGLTLLIFYYSFAIVGMEFFCGIVFPNCCNTSTVADAYRWRNHTVGNRTVVEEGYYY
LNNFDNILNSFVTLFELTVVNNWYIIMEGVTSQTSHWSRLYFMTFYIVTMVVMTIIVAFILEAFVFRMNYSRKNQDSEVDGGITLEKEIS
KEELVAVLELYREARGASSDVTRLLETLSQMERYQQHSMVFLGRRSRTKSDLSLKMYQEEIQEWYEEHAREQEQQRQLSSSAAPAAQQPP

--------------------------------------------------------------
>85743_85743_4_SPG11-TPCN1_SPG11_chr15_44925703_ENST00000261866_TPCN1_chr12_113723694_ENST00000550785_length(transcript)=5259nt_BP=1752nt
GTAACCGCCGGGCCAAGATGGCTGCAGAGGAAGGGGTCGCGAGTGCTGCTTCCGCCGGCGGTAGCTGGGGCACCGCGGCCATGGGGCGGG
TTCTACCGATGCTGTTGGTGCCAGTCCCCGCCGAGGCGATGGGGCAGCTCGGCTCCCGGGCGCAGCTGCGCACACAGCCGGAGGCTCTGG
GGAGCCTGACGGCTGCGGGCAGCCTCCAAGTGCTTTCTTTGACGCCTGGCAGCCGGGGCGGGGGTCGCTGCTGCCTGGAGGGCCCCTTCT
GGCACTTTCTATGGGAGGATTCTCGTAACAGCAGCACACCAACTGAAAAGCCCAAACTGCTCGCTCTTGGTGAAAATTATGAACTGCTTA
TCTATGAATTTAATTTGAAAGATGGAAGATGTGATGCAACCATTTTGTATAGCTGTAGTAGGGAGGCATTGCAAAAGCTCATTGACGATC
AAGATATCAGTATTTCCTTATTGTCTTTGAGAATCCTGTCATTTCACAATAACACATCATTACTGTTCATCAACAAATGTGTCATCCTAC
ATATTATATTTCCTGAAAGAGATGCTGCAATTAGAGTACTCAACTGTTTCACACTTCCCTTGCCTGCACAGGCAGTGGACATGATTATTG
ACACGCAGCTCTGCAGAGGAATTCTTTTTGTTTTGAGTAGTTTAGGCTGGATCTACATTTTTGATGTTGTGGATGGTACATATGTAGCTC
ATGTGGATTTAGCACTTCACAAAGAAGACATGTGTAATGAGCAGCAACAGGAGCCAGCCAAGATTTCTTCATTTACTTCACTGAAAGTTT
CTCAAGACCTCGATGTTGCAGTGATTGTCAGCTCCTCCAACTCCGCAGTTGCTCTTAACTTAAATTTGTATTTCAGGCAACACCCAGGAC
ACCTACTGTGTGAAAGAATACTAGAAGATCTTCCTATTCAAGGACCTAAGGGCGTAGATGAAGATGATCCTGTTAACTCTGCCTACAACA
TGAAACTGGCCAAGTTTTCCTTCCAAATTGATAGGTCTTGGAAAGCCCAGCTATCATCATTGAATGAAACAATAAAGAACTCCAAACTGG
AGGTTTCCTGTTGTGCTCCATGGTTCCAGGATATTTTGCATTTGGAGTCACCTGAATCTGGTAACCACAGTACAAGTGTGCAGAGCTGGG
CCTTCATTCCACAGGACATAATGCATGGGCAATATAATGTTCTACAGAAAGATCATGCCAAGACCAGTGATCCAGGAAGATCATGGAAAA
TAATGCACATCAGTGAACAAGAGGAACCCATAGAGCTTAAATGTGTGTCTGTGACAGGATTCACTGCACTGTTTACTTGGGAAGTGGAAA
GGATGGGCTATACCATTACCCTCTGGGATTTGGAGACCCAGGGCATGCAGTGTTTTTCCCTTGGCACAAAGTGTATTCCTGTAGACAGTA
GTGGAGACCAGCAGCTGTGCTTTGTTTTGACAGAGAATGGACTCTCTCTGATTTTGTTTGGTTTGACTCAAGAAGAGTTTTTAAACAGAC
TCATGATCCATGGAAGTGCCAGCACTGTGGACACTCTTTGTCATCTCAATGGCTGGGGAAGGTGCTCAATTCCCATACATGCACTAGAGG
CCGGGATAGAAAATCGTCAGCTGGACACAGTAAATTTCTTTTTGAAGAGCAAGGAAAATCTTTTTAATCCATCCTCAAAATCTTCTGTAT
CTGATCAGTTTGATCACTTGTCATCCCATTTATATTTAAGAATCTATGGGGTGGAGCTGTTCCTGAAGGTTGCCGGCCTGGGCCCTGTGG
AGTACTTGTCTTCCGGATGGAACTTGTTTGACTTCTCCGTGACAGTGTTCGCCTTCCTGGGACTGCTGGCGCTGGCCCTCAACATGGAGC
CCTTCTATTTCATCGTGGTCCTGCGCCCCCTCCAGCTGCTGAGGTTGTTTAAGTTGAAGGAGCGCTACCGCAACGTGCTGGACACCATGT
TCGAGCTGCTGCCCCGGATGGCCAGCCTGGGCCTCACCCTGCTCATCTTTTACTACTCCTTCGCCATCGTGGGCATGGAGTTCTTCTGCG
GGATCGTCTTCCCCAACTGCTGCAACACGAGTACAGTGGCAGATGCCTACCGCTGGCGCAACCACACCGTGGGCAACAGGACCGTGGTGG
AGGAAGGCTACTATTATCTCAATAATTTTGACAACATCCTCAACAGCTTTGTGACCCTGTTTGAGCTCACAGTTGTCAACAACTGGTACA
TCATCATGGAAGGCGTCACCTCTCAGACCTCCCACTGGAGCCGCCTCTACTTCATGACCTTTTACATTGTGACCATGGTGGTGATGACGA
TCATTGTCGCCTTTATCCTCGAGGCCTTCGTCTTCCGAATGAACTACAGCCGCAAGAACCAGGACTCGGAAGTTGATGGTGGCATCACCC
TTGAGAAGGAAATCTCCAAAGAAGAGCTGGTTGCCGTCCTGGAGCTCTACCGGGAGGCACGGGGGGCCTCCTCGGATGTCACCAGGCTGC
TGGAGACCCTCTCCCAGATGGAGAGATACCAGCAACATTCCATGGTGTTTCTGGGACGGCGATCAAGGACCAAGAGCGACCTGAGCCTGA
AGATGTACCAGGAGGAGATCCAGGAGTGGTATGAGGAGCATGCCAGGGAGCAAGAGCAGCAGCGACAACTCAGCAGCAGTGCAGCCCCCG
CCGCCCAGCAGCCCCCAGGCAGCCGCCAGCGCTCCCAGACCGTTACCTAGCCCAGCGCCCGAAAGCCGTCTCTTCTATGCAATAACACAA
TAGTATTACTCTACTGCGATGTACGGAACTGCGGTGTGTGTACACATACTCACGTATATGCACATATTTATATACAGGAAGAAAAAAGAC
AGACAAGATGGGGCTTGGTTTATAACCACCTTGCCCTGTCTTCCTTAACTCCAGAAGCCAGTTTGGTGAGGGGTGGGGGTGCGGCCACCA
GGTCTGAGCTCTTCCTACTGTGGAAGGCTCCAGAAGGCCCTTCACAAGGAGACCCCTCACCTGGATCCAGTCGACTGCGGGGCTTGCCCC
TCATGTGGGCTGGCCTCCATCGGCCACGTCCAAAGCTGTCACTGCTACTGCTTCAGGCTCACATCCCCCCGACCTGATGGCGTGCCCGCC
CCCTCTCCCTGCGGCCCATGCCACAGGTTTCTGTGTTTTGCTTTAGGGACAGAACCACTTAGGAAGGAAAGAACTCCCGGTCTCCAGGGT
GGTATTTCAGTGTCTGTGATAATGTCACGCAACACCTCTTCGGGGACCAGTGCCCAGGATCTAATGGAAGCGGAATTGGGGCAACTGGGC
CCATGTGGCCAGAGCTCAGTTAGCCAGTGCCGGGCGGCCACAGATTACACTGACCAATCTCCTCCCTTGGCTCTGCAAGCCTCCCACCCA
GCCTTCTCTGGCTTAACCCTTGTTGGCGAAAACTCTTCCACAGTGGCCTCCTTGGGGACCCAGAACCCGGAGGAAGGGGCATGAGGCAGG
AAGTGGGGCCGATGTCTGCAACCCAGACCACTTCGTGGAATGGGCTCTTGACCAAATCCCTTTTTTTGCGATTTACCCGTTCAAGCAAAA
CAACGTTTTGGTTAACTAAGGATTGTGCTAAAGCCGATACCAGGTCCTTCACACGTGTGCACTAGGAACAGGAGCGAACAGCACAGAGAG
ACGCTCCCTGTGGGACGCAGCAGCCCCGTGGCCCCGGCCCAGTTCCCAGCCACCCTCCCTGGCTCTGCTCACACCAGAGATTTCCATAGC
AGGAGCGGTTGGTGCAGAAGTAGGTTCAGATGAACCTCAGTTAACGTCGCCACCCCTCCTCCCACCATGGTACCCTGTAGGAGCCCTGTA
TGACATCTGAGCGTGGTGGAGGTAGGAGGGTTGCCAGCTGCAGTGACCCTGCCACAGAGGCAGGGTCAGTGCAGAGGTCGCTTTGGTTCC
GCTTCCCTGGGCCACAGAACGGAACACAGCATAGGTTCTGCAGCAGGAGCCGCAGTGGCAGGATGGAGGGTGCGAAGGGCAAGGAGTGCA
CTGCTGGGCATTCCTGGCCAGCCCCGGCCCTCTGGTGCCTGCTTCCTGTGACTTCAGAAGGCAGGTGGACAGAGCCTCCCTCTGGCCTTG
TCCTCTTCCCAGCCACAGAACGGGCAGGGTGGCACCCGACCCCAGGGGAGCAGTACCTGGTCCCCCACCCCCTCCTCCCAACCACCTCCA
AGGCCAAGCTGGGTCCCATAGCCAGCACGGCATGGTTCTCCCCTTCCCCCCTTCCCAGGTCAGGGGAGTTGGACAAGTAGCAGGTGTTTG
TTTTTAAAGCACAGCCCTTTGGGAAAGCAACACATTATTGAGACTCACTGTGATTCCCCCGGGAGTCAGACTGGCTTTGTCCTCTTCCTC
TCTGGAGGGCCATGGGCCATCAGCAGGAGCTCCACATCGAGCCCCAGGCCAGAACCCCCTCCCTTTCACAGAGAGGGAACTTTATTGCAC
AATTGGGTGCCTTTTAGCTTTTGTGTGTTGAAATGGGCGTTTTGGAAGCAAGGGTCAGGGGACAGCTTCTAAAGGTGTGAGTCTCTGACC
TGAGCATCTGGGCCTCGCCTGGGCCCTTCTTCCTCCCCAGGGGTGGAAACGTGGAGGGGCCAGCAGCACCCCGGGGTCTGCCCAGGGGAG
TCAAGGCCCCGAGGTGGGGGGGCCTATTCCAGGAGGAGTGGGATCTCGGCCCTGTCCAGAGCGAGTTAATGTGTCCATCTGCCCAACCCT
GTCCTGAGAAAGGACCTGGTTTTGGCCAGGACCTGACAAATACCCAATGGCAGCAGTGTCAACAGACGGGAGTCCAGCCAGGGTGGGTGC
CCTTGTCATTGAGGTTAGGGACAGCTATCCCCAGGTTATGCCTGGCCCCACCCAGCAGGGAGTTGGGGTCCCCCCACAGGCTGTGAGCTC
TGTGGGCCCTGGGATGTGATCTAGCTCAGATGCCCTCTCATCCTTGATGTCATAGTTGAGTGCACCCAAGTGGCACCCACTGGCGGCCAG
GGGCACAGCCTGGTGGTGGTGGCAATAGAACTGTGCCCCTCCTCAGCTCCTCGCTTCCCCTCCCACAGCCCCAGCCTTACTCCACCATGC
GGACAATCATTTTGTACGGATCACGGGAGCAATGCTGTACGGTTTTGTACACTGGTGGTTTGTTTCCTAGAAAACCCATTGTGTCTCTGG

>85743_85743_4_SPG11-TPCN1_SPG11_chr15_44925703_ENST00000261866_TPCN1_chr12_113723694_ENST00000550785_length(amino acids)=910AA_BP=579
MAAEEGVASAASAGGSWGTAAMGRVLPMLLVPVPAEAMGQLGSRAQLRTQPEALGSLTAAGSLQVLSLTPGSRGGGRCCLEGPFWHFLWE
DSRNSSTPTEKPKLLALGENYELLIYEFNLKDGRCDATILYSCSREALQKLIDDQDISISLLSLRILSFHNNTSLLFINKCVILHIIFPE
RDAAIRVLNCFTLPLPAQAVDMIIDTQLCRGILFVLSSLGWIYIFDVVDGTYVAHVDLALHKEDMCNEQQQEPAKISSFTSLKVSQDLDV
AVIVSSSNSAVALNLNLYFRQHPGHLLCERILEDLPIQGPKGVDEDDPVNSAYNMKLAKFSFQIDRSWKAQLSSLNETIKNSKLEVSCCA
PWFQDILHLESPESGNHSTSVQSWAFIPQDIMHGQYNVLQKDHAKTSDPGRSWKIMHISEQEEPIELKCVSVTGFTALFTWEVERMGYTI
TLWDLETQGMQCFSLGTKCIPVDSSGDQQLCFVLTENGLSLILFGLTQEEFLNRLMIHGSASTVDTLCHLNGWGRCSIPIHALEAGIENR
QLDTVNFFLKSKENLFNPSSKSSVSDQFDHLSSHLYLRIYGVELFLKVAGLGPVEYLSSGWNLFDFSVTVFAFLGLLALALNMEPFYFIV
VLRPLQLLRLFKLKERYRNVLDTMFELLPRMASLGLTLLIFYYSFAIVGMEFFCGIVFPNCCNTSTVADAYRWRNHTVGNRTVVEEGYYY
LNNFDNILNSFVTLFELTVVNNWYIIMEGVTSQTSHWSRLYFMTFYIVTMVVMTIIVAFILEAFVFRMNYSRKNQDSEVDGGITLEKEIS
KEELVAVLELYREARGASSDVTRLLETLSQMERYQQHSMVFLGRRSRTKSDLSLKMYQEEIQEWYEEHAREQEQQRQLSSSAAPAAQQPP

--------------------------------------------------------------
>85743_85743_5_SPG11-TPCN1_SPG11_chr15_44925703_ENST00000427534_TPCN1_chr12_113723694_ENST00000335509_length(transcript)=5242nt_BP=1735nt
ATGGCTGCAGAGGAAGGGGTCGCGAGTGCTGCTTCCGCCGGCGGTAGCTGGGGCACCGCGGCCATGGGGCGGGTTCTACCGATGCTGTTG
GTGCCAGTCCCCGCCGAGGCGATGGGGCAGCTCGGCTCCCGGGCGCAGCTGCGCACACAGCCGGAGGCTCTGGGGAGCCTGACGGCTGCG
GGCAGCCTCCAAGTGCTTTCTTTGACGCCTGGCAGCCGGGGCGGGGGTCGCTGCTGCCTGGAGGGCCCCTTCTGGCACTTTCTATGGGAG
GATTCTCGTAACAGCAGCACACCAACTGAAAAGCCCAAACTGCTCGCTCTTGGTGAAAATTATGAACTGCTTATCTATGAATTTAATTTG
AAAGATGGAAGATGTGATGCAACCATTTTGTATAGCTGTAGTAGGGAGGCATTGCAAAAGCTCATTGACGATCAAGATATCAGTATTTCC
TTATTGTCTTTGAGAATCCTGTCATTTCACAATAACACATCATTACTGTTCATCAACAAATGTGTCATCCTACATATTATATTTCCTGAA
AGAGATGCTGCAATTAGAGTACTCAACTGTTTCACACTTCCCTTGCCTGCACAGGCAGTGGACATGATTATTGACACGCAGCTCTGCAGA
GGAATTCTTTTTGTTTTGAGTAGTTTAGGCTGGATCTACATTTTTGATGTTGTGGATGGTACATATGTAGCTCATGTGGATTTAGCACTT
CACAAAGAAGACATGTGTAATGAGCAGCAACAGGAGCCAGCCAAGATTTCTTCATTTACTTCACTGAAAGTTTCTCAAGACCTCGATGTT
GCAGTGATTGTCAGCTCCTCCAACTCCGCAGTTGCTCTTAACTTAAATTTGTATTTCAGGCAACACCCAGGACACCTACTGTGTGAAAGA
ATACTAGAAGATCTTCCTATTCAAGGACCTAAGGGCGTAGATGAAGATGATCCTGTTAACTCTGCCTACAACATGAAACTGGCCAAGTTT
TCCTTCCAAATTGATAGGTCTTGGAAAGCCCAGCTATCATCATTGAATGAAACAATAAAGAACTCCAAACTGGAGGTTTCCTGTTGTGCT
CCATGGTTCCAGGATATTTTGCATTTGGAGTCACCTGAATCTGGTAACCACAGTACAAGTGTGCAGAGCTGGGCCTTCATTCCACAGGAC
ATAATGCATGGGCAATATAATGTTCTACAGAAAGATCATGCCAAGACCAGTGATCCAGGAAGATCATGGAAAATAATGCACATCAGTGAA
CAAGAGGAACCCATAGAGCTTAAATGTGTGTCTGTGACAGGATTCACTGCACTGTTTACTTGGGAAGTGGAAAGGATGGGCTATACCATT
ACCCTCTGGGATTTGGAGACCCAGGGCATGCAGTGTTTTTCCCTTGGCACAAAGTGTATTCCTGTAGACAGTAGTGGAGACCAGCAGCTG
TGCTTTGTTTTGACAGAGAATGGACTCTCTCTGATTTTGTTTGGTTTGACTCAAGAAGAGTTTTTAAACAGACTCATGATCCATGGAAGT
GCCAGCACTGTGGACACTCTTTGTCATCTCAATGGCTGGGGAAGGTGCTCAATTCCCATACATGCACTAGAGGCCGGGATAGAAAATCGT
CAGCTGGACACAGTAAATTTCTTTTTGAAGAGCAAGGAAAATCTTTTTAATCCATCCTCAAAATCTTCTGTATCTGATCAGTTTGATCAC
TTGTCATCCCATTTATATTTAAGAATCTATGGGGTGGAGCTGTTCCTGAAGGTTGCCGGCCTGGGCCCTGTGGAGTACTTGTCTTCCGGA
TGGAACTTGTTTGACTTCTCCGTGACAGTGTTCGCCTTCCTGGGACTGCTGGCGCTGGCCCTCAACATGGAGCCCTTCTATTTCATCGTG
GTCCTGCGCCCCCTCCAGCTGCTGAGGTTGTTTAAGTTGAAGGAGCGCTACCGCAACGTGCTGGACACCATGTTCGAGCTGCTGCCCCGG
ATGGCCAGCCTGGGCCTCACCCTGCTCATCTTTTACTACTCCTTCGCCATCGTGGGCATGGAGTTCTTCTGCGGGATCGTCTTCCCCAAC
TGCTGCAACACGAGTACAGTGGCAGATGCCTACCGCTGGCGCAACCACACCGTGGGCAACAGGACCGTGGTGGAGGAAGGCTACTATTAT
CTCAATAATTTTGACAACATCCTCAACAGCTTTGTGACCCTGTTTGAGCTCACAGTTGTCAACAACTGGTACATCATCATGGAAGGCGTC
ACCTCTCAGACCTCCCACTGGAGCCGCCTCTACTTCATGACCTTTTACATTGTGACCATGGTGGTGATGACGATCATTGTCGCCTTTATC
CTCGAGGCCTTCGTCTTCCGAATGAACTACAGCCGCAAGAACCAGGACTCGGAAGTTGATGGTGGCATCACCCTTGAGAAGGAAATCTCC
AAAGAAGAGCTGGTTGCCGTCCTGGAGCTCTACCGGGAGGCACGGGGGGCCTCCTCGGATGTCACCAGGCTGCTGGAGACCCTCTCCCAG
ATGGAGAGATACCAGCAACATTCCATGGTGTTTCTGGGACGGCGATCAAGGACCAAGAGCGACCTGAGCCTGAAGATGTACCAGGAGGAG
ATCCAGGAGTGGTATGAGGAGCATGCCAGGGAGCAAGAGCAGCAGCGACAACTCAGCAGCAGTGCAGCCCCCGCCGCCCAGCAGCCCCCA
GGCAGCCGCCAGCGCTCCCAGACCGTTACCTAGCCCAGCGCCCGAAAGCCGTCTCTTCTATGCAATAACACAATAGTATTACTCTACTGC
GATGTACGGAACTGCGGTGTGTGTACACATACTCACGTATATGCACATATTTATATACAGGAAGAAAAAAGACAGACAAGATGGGGCTTG
GTTTATAACCACCTTGCCCTGTCTTCCTTAACTCCAGAAGCCAGTTTGGTGAGGGGTGGGGGTGCGGCCACCAGGTCTGAGCTCTTCCTA
CTGTGGAAGGCTCCAGAAGGCCCTTCACAAGGAGACCCCTCACCTGGATCCAGTCGACTGCGGGGCTTGCCCCTCATGTGGGCTGGCCTC
CATCGGCCACGTCCAAAGCTGTCACTGCTACTGCTTCAGGCTCACATCCCCCCGACCTGATGGCGTGCCCGCCCCCTCTCCCTGCGGCCC
ATGCCACAGGTTTCTGTGTTTTGCTTTAGGGACAGAACCACTTAGGAAGGAAAGAACTCCCGGTCTCCAGGGTGGTATTTCAGTGTCTGT
GATAATGTCACGCAACACCTCTTCGGGGACCAGTGCCCAGGATCTAATGGAAGCGGAATTGGGGCAACTGGGCCCATGTGGCCAGAGCTC
AGTTAGCCAGTGCCGGGCGGCCACAGATTACACTGACCAATCTCCTCCCTTGGCTCTGCAAGCCTCCCACCCAGCCTTCTCTGGCTTAAC
CCTTGTTGGCGAAAACTCTTCCACAGTGGCCTCCTTGGGGACCCAGAACCCGGAGGAAGGGGCATGAGGCAGGAAGTGGGGCCGATGTCT
GCAACCCAGACCACTTCGTGGAATGGGCTCTTGACCAAATCCCTTTTTTTGCGATTTACCCGTTCAAGCAAAACAACGTTTTGGTTAACT
AAGGATTGTGCTAAAGCCGATACCAGGTCCTTCACACGTGTGCACTAGGAACAGGAGCGAACAGCACAGAGAGACGCTCCCTGTGGGACG
CAGCAGCCCCGTGGCCCCGGCCCAGTTCCCAGCCACCCTCCCTGGCTCTGCTCACACCAGAGATTTCCATAGCAGGAGCGGTTGGTGCAG
AAGTAGGTTCAGATGAACCTCAGTTAACGTCGCCACCCCTCCTCCCACCATGGTACCCTGTAGGAGCCCTGTATGACATCTGAGCGTGGT
GGAGGTAGGAGGGTTGCCAGCTGCAGTGACCCTGCCACAGAGGCAGGGTCAGTGCAGAGGTCGCTTTGGTTCCGCTTCCCTGGGCCACAG
AACGGAACACAGCATAGGTTCTGCAGCAGGAGCCGCAGTGGCAGGATGGAGGGTGCGAAGGGCAAGGAGTGCACTGCTGGGCATTCCTGG
CCAGCCCCGGCCCTCTGGTGCCTGCTTCCTGTGACTTCAGAAGGCAGGTGGACAGAGCCTCCCTCTGGCCTTGTCCTCTTCCCAGCCACA
GAACGGGCAGGGTGGCACCCGACCCCAGGGGAGCAGTACCTGGTCCCCCACCCCCTCCTCCCAACCACCTCCAAGGCCAAGCTGGGTCCC
ATAGCCAGCACGGCATGGTTCTCCCCTTCCCCCCTTCCCAGGTCAGGGGAGTTGGACAAGTAGCAGGTGTTTGTTTTTAAAGCACAGCCC
TTTGGGAAAGCAACACATTATTGAGACTCACTGTGATTCCCCCGGGAGTCAGACTGGCTTTGTCCTCTTCCTCTCTGGAGGGCCATGGGC
CATCAGCAGGAGCTCCACATCGAGCCCCAGGCCAGAACCCCCTCCCTTTCACAGAGAGGGAACTTTATTGCACAATTGGGTGCCTTTTAG
CTTTTGTGTGTTGAAATGGGCGTTTTGGAAGCAAGGGTCAGGGGACAGCTTCTAAAGGTGTGAGTCTCTGACCTGAGCATCTGGGCCTCG
CCTGGGCCCTTCTTCCTCCCCAGGGGTGGAAACGTGGAGGGGCCAGCAGCACCCCGGGGTCTGCCCAGGGGAGTCAAGGCCCCGAGGTGG
GGGGGCCTATTCCAGGAGGAGTGGGATCTCGGCCCTGTCCAGAGCGAGTTAATGTGTCCATCTGCCCAACCCTGTCCTGAGAAAGGACCT
GGTTTTGGCCAGGACCTGACAAATACCCAATGGCAGCAGTGTCAACAGACGGGAGTCCAGCCAGGGTGGGTGCCCTTGTCATTGAGGTTA
GGGACAGCTATCCCCAGGTTATGCCTGGCCCCACCCAGCAGGGAGTTGGGGTCCCCCCACAGGCTGTGAGCTCTGTGGGCCCTGGGATGT
GATCTAGCTCAGATGCCCTCTCATCCTTGATGTCATAGTTGAGTGCACCCAAGTGGCACCCACTGGCGGCCAGGGGCACAGCCTGGTGGT
GGTGGCAATAGAACTGTGCCCCTCCTCAGCTCCTCGCTTCCCCTCCCACAGCCCCAGCCTTACTCCACCATGCGGACAATCATTTTGTAC
GGATCACGGGAGCAATGCTGTACGGTTTTGTACACTGGTGGTTTGTTTCCTAGAAAACCCATTGTGTCTCTGGATTTCTAGCACATTACT

>85743_85743_5_SPG11-TPCN1_SPG11_chr15_44925703_ENST00000427534_TPCN1_chr12_113723694_ENST00000335509_length(amino acids)=910AA_BP=579
MAAEEGVASAASAGGSWGTAAMGRVLPMLLVPVPAEAMGQLGSRAQLRTQPEALGSLTAAGSLQVLSLTPGSRGGGRCCLEGPFWHFLWE
DSRNSSTPTEKPKLLALGENYELLIYEFNLKDGRCDATILYSCSREALQKLIDDQDISISLLSLRILSFHNNTSLLFINKCVILHIIFPE
RDAAIRVLNCFTLPLPAQAVDMIIDTQLCRGILFVLSSLGWIYIFDVVDGTYVAHVDLALHKEDMCNEQQQEPAKISSFTSLKVSQDLDV
AVIVSSSNSAVALNLNLYFRQHPGHLLCERILEDLPIQGPKGVDEDDPVNSAYNMKLAKFSFQIDRSWKAQLSSLNETIKNSKLEVSCCA
PWFQDILHLESPESGNHSTSVQSWAFIPQDIMHGQYNVLQKDHAKTSDPGRSWKIMHISEQEEPIELKCVSVTGFTALFTWEVERMGYTI
TLWDLETQGMQCFSLGTKCIPVDSSGDQQLCFVLTENGLSLILFGLTQEEFLNRLMIHGSASTVDTLCHLNGWGRCSIPIHALEAGIENR
QLDTVNFFLKSKENLFNPSSKSSVSDQFDHLSSHLYLRIYGVELFLKVAGLGPVEYLSSGWNLFDFSVTVFAFLGLLALALNMEPFYFIV
VLRPLQLLRLFKLKERYRNVLDTMFELLPRMASLGLTLLIFYYSFAIVGMEFFCGIVFPNCCNTSTVADAYRWRNHTVGNRTVVEEGYYY
LNNFDNILNSFVTLFELTVVNNWYIIMEGVTSQTSHWSRLYFMTFYIVTMVVMTIIVAFILEAFVFRMNYSRKNQDSEVDGGITLEKEIS
KEELVAVLELYREARGASSDVTRLLETLSQMERYQQHSMVFLGRRSRTKSDLSLKMYQEEIQEWYEEHAREQEQQRQLSSSAAPAAQQPP

--------------------------------------------------------------
>85743_85743_6_SPG11-TPCN1_SPG11_chr15_44925703_ENST00000427534_TPCN1_chr12_113723694_ENST00000392569_length(transcript)=2851nt_BP=1735nt
ATGGCTGCAGAGGAAGGGGTCGCGAGTGCTGCTTCCGCCGGCGGTAGCTGGGGCACCGCGGCCATGGGGCGGGTTCTACCGATGCTGTTG
GTGCCAGTCCCCGCCGAGGCGATGGGGCAGCTCGGCTCCCGGGCGCAGCTGCGCACACAGCCGGAGGCTCTGGGGAGCCTGACGGCTGCG
GGCAGCCTCCAAGTGCTTTCTTTGACGCCTGGCAGCCGGGGCGGGGGTCGCTGCTGCCTGGAGGGCCCCTTCTGGCACTTTCTATGGGAG
GATTCTCGTAACAGCAGCACACCAACTGAAAAGCCCAAACTGCTCGCTCTTGGTGAAAATTATGAACTGCTTATCTATGAATTTAATTTG
AAAGATGGAAGATGTGATGCAACCATTTTGTATAGCTGTAGTAGGGAGGCATTGCAAAAGCTCATTGACGATCAAGATATCAGTATTTCC
TTATTGTCTTTGAGAATCCTGTCATTTCACAATAACACATCATTACTGTTCATCAACAAATGTGTCATCCTACATATTATATTTCCTGAA
AGAGATGCTGCAATTAGAGTACTCAACTGTTTCACACTTCCCTTGCCTGCACAGGCAGTGGACATGATTATTGACACGCAGCTCTGCAGA
GGAATTCTTTTTGTTTTGAGTAGTTTAGGCTGGATCTACATTTTTGATGTTGTGGATGGTACATATGTAGCTCATGTGGATTTAGCACTT
CACAAAGAAGACATGTGTAATGAGCAGCAACAGGAGCCAGCCAAGATTTCTTCATTTACTTCACTGAAAGTTTCTCAAGACCTCGATGTT
GCAGTGATTGTCAGCTCCTCCAACTCCGCAGTTGCTCTTAACTTAAATTTGTATTTCAGGCAACACCCAGGACACCTACTGTGTGAAAGA
ATACTAGAAGATCTTCCTATTCAAGGACCTAAGGGCGTAGATGAAGATGATCCTGTTAACTCTGCCTACAACATGAAACTGGCCAAGTTT
TCCTTCCAAATTGATAGGTCTTGGAAAGCCCAGCTATCATCATTGAATGAAACAATAAAGAACTCCAAACTGGAGGTTTCCTGTTGTGCT
CCATGGTTCCAGGATATTTTGCATTTGGAGTCACCTGAATCTGGTAACCACAGTACAAGTGTGCAGAGCTGGGCCTTCATTCCACAGGAC
ATAATGCATGGGCAATATAATGTTCTACAGAAAGATCATGCCAAGACCAGTGATCCAGGAAGATCATGGAAAATAATGCACATCAGTGAA
CAAGAGGAACCCATAGAGCTTAAATGTGTGTCTGTGACAGGATTCACTGCACTGTTTACTTGGGAAGTGGAAAGGATGGGCTATACCATT
ACCCTCTGGGATTTGGAGACCCAGGGCATGCAGTGTTTTTCCCTTGGCACAAAGTGTATTCCTGTAGACAGTAGTGGAGACCAGCAGCTG
TGCTTTGTTTTGACAGAGAATGGACTCTCTCTGATTTTGTTTGGTTTGACTCAAGAAGAGTTTTTAAACAGACTCATGATCCATGGAAGT
GCCAGCACTGTGGACACTCTTTGTCATCTCAATGGCTGGGGAAGGTGCTCAATTCCCATACATGCACTAGAGGCCGGGATAGAAAATCGT
CAGCTGGACACAGTAAATTTCTTTTTGAAGAGCAAGGAAAATCTTTTTAATCCATCCTCAAAATCTTCTGTATCTGATCAGTTTGATCAC
TTGTCATCCCATTTATATTTAAGAATCTATGGGGTGGAGCTGTTCCTGAAGGTTGCCGGCCTGGGCCCTGTGGAGTACTTGTCTTCCGGA
TGGAACTTGTTTGACTTCTCCGTGACAGTGTTCGCCTTCCTGGGACTGCTGGCGCTGGCCCTCAACATGGAGCCCTTCTATTTCATCGTG
GTCCTGCGCCCCCTCCAGCTGCTGAGGTTGTTTAAGTTGAAGGAGCGCTACCGCAACGTGCTGGACACCATGTTCGAGCTGCTGCCCCGG
ATGGCCAGCCTGGGCCTCACCCTGCTCATCTTTTACTACTCCTTCGCCATCGTGGGCATGGAGTTCTTCTGCGGGATCGTCTTCCCCAAC
TGCTGCAACACGAGTACAGTGGCAGATGCCTACCGCTGGCGCAACCACACCGTGGGCAACAGGACCGTGGTGGAGGAAGGCTACTATTAT
CTCAATAATTTTGACAACATCCTCAACAGCTTTGTGACCCTGTTTGAGCTCACAGTTGTCAACAACTGGTACATCATCATGGAAGGCGTC
ACCTCTCAGACCTCCCACTGGAGCCGCCTCTACTTCATGACCTTTTACATTGTGACCATGGTGGTGATGACGATCATTGTCGCCTTTATC
CTCGAGGCCTTCGTCTTCCGAATGAACTACAGCCGCAAGAACCAGGACTCGGAAGTTGATGGTGGCATCACCCTTGAGAAGGAAATCTCC
AAAGAAGAGCTGGTTGCCGTCCTGGAGCTCTACCGGGAGGCACGGGGGGCCTCCTCGGATGTCACCAGGCTGCTGGAGACCCTCTCCCAG
ATGGAGAGATACCAGCAACATTCCATGGTGTTTCTGGGACGGCGATCAAGGACCAAGAGCGACCTGAGCCTGAAGATGTACCAGGAGGAG
ATCCAGGAGTGGTATGAGGAGCATGCCAGGGAGCAAGAGCAGCAGCGACAACTCAGCAGCAGTGCAGCCCCCGCCGCCCAGCAGCCCCCA
GGCAGCCGCCAGCGCTCCCAGACCGTTACCTAGCCCAGCGCCCGAAAGCCGTCTCTTCTATGCAATAACACAATAGTATTACTCTACTGC

>85743_85743_6_SPG11-TPCN1_SPG11_chr15_44925703_ENST00000427534_TPCN1_chr12_113723694_ENST00000392569_length(amino acids)=910AA_BP=579
MAAEEGVASAASAGGSWGTAAMGRVLPMLLVPVPAEAMGQLGSRAQLRTQPEALGSLTAAGSLQVLSLTPGSRGGGRCCLEGPFWHFLWE
DSRNSSTPTEKPKLLALGENYELLIYEFNLKDGRCDATILYSCSREALQKLIDDQDISISLLSLRILSFHNNTSLLFINKCVILHIIFPE
RDAAIRVLNCFTLPLPAQAVDMIIDTQLCRGILFVLSSLGWIYIFDVVDGTYVAHVDLALHKEDMCNEQQQEPAKISSFTSLKVSQDLDV
AVIVSSSNSAVALNLNLYFRQHPGHLLCERILEDLPIQGPKGVDEDDPVNSAYNMKLAKFSFQIDRSWKAQLSSLNETIKNSKLEVSCCA
PWFQDILHLESPESGNHSTSVQSWAFIPQDIMHGQYNVLQKDHAKTSDPGRSWKIMHISEQEEPIELKCVSVTGFTALFTWEVERMGYTI
TLWDLETQGMQCFSLGTKCIPVDSSGDQQLCFVLTENGLSLILFGLTQEEFLNRLMIHGSASTVDTLCHLNGWGRCSIPIHALEAGIENR
QLDTVNFFLKSKENLFNPSSKSSVSDQFDHLSSHLYLRIYGVELFLKVAGLGPVEYLSSGWNLFDFSVTVFAFLGLLALALNMEPFYFIV
VLRPLQLLRLFKLKERYRNVLDTMFELLPRMASLGLTLLIFYYSFAIVGMEFFCGIVFPNCCNTSTVADAYRWRNHTVGNRTVVEEGYYY
LNNFDNILNSFVTLFELTVVNNWYIIMEGVTSQTSHWSRLYFMTFYIVTMVVMTIIVAFILEAFVFRMNYSRKNQDSEVDGGITLEKEIS
KEELVAVLELYREARGASSDVTRLLETLSQMERYQQHSMVFLGRRSRTKSDLSLKMYQEEIQEWYEEHAREQEQQRQLSSSAAPAAQQPP

--------------------------------------------------------------
>85743_85743_7_SPG11-TPCN1_SPG11_chr15_44925703_ENST00000427534_TPCN1_chr12_113723694_ENST00000541517_length(transcript)=5239nt_BP=1735nt
ATGGCTGCAGAGGAAGGGGTCGCGAGTGCTGCTTCCGCCGGCGGTAGCTGGGGCACCGCGGCCATGGGGCGGGTTCTACCGATGCTGTTG
GTGCCAGTCCCCGCCGAGGCGATGGGGCAGCTCGGCTCCCGGGCGCAGCTGCGCACACAGCCGGAGGCTCTGGGGAGCCTGACGGCTGCG
GGCAGCCTCCAAGTGCTTTCTTTGACGCCTGGCAGCCGGGGCGGGGGTCGCTGCTGCCTGGAGGGCCCCTTCTGGCACTTTCTATGGGAG
GATTCTCGTAACAGCAGCACACCAACTGAAAAGCCCAAACTGCTCGCTCTTGGTGAAAATTATGAACTGCTTATCTATGAATTTAATTTG
AAAGATGGAAGATGTGATGCAACCATTTTGTATAGCTGTAGTAGGGAGGCATTGCAAAAGCTCATTGACGATCAAGATATCAGTATTTCC
TTATTGTCTTTGAGAATCCTGTCATTTCACAATAACACATCATTACTGTTCATCAACAAATGTGTCATCCTACATATTATATTTCCTGAA
AGAGATGCTGCAATTAGAGTACTCAACTGTTTCACACTTCCCTTGCCTGCACAGGCAGTGGACATGATTATTGACACGCAGCTCTGCAGA
GGAATTCTTTTTGTTTTGAGTAGTTTAGGCTGGATCTACATTTTTGATGTTGTGGATGGTACATATGTAGCTCATGTGGATTTAGCACTT
CACAAAGAAGACATGTGTAATGAGCAGCAACAGGAGCCAGCCAAGATTTCTTCATTTACTTCACTGAAAGTTTCTCAAGACCTCGATGTT
GCAGTGATTGTCAGCTCCTCCAACTCCGCAGTTGCTCTTAACTTAAATTTGTATTTCAGGCAACACCCAGGACACCTACTGTGTGAAAGA
ATACTAGAAGATCTTCCTATTCAAGGACCTAAGGGCGTAGATGAAGATGATCCTGTTAACTCTGCCTACAACATGAAACTGGCCAAGTTT
TCCTTCCAAATTGATAGGTCTTGGAAAGCCCAGCTATCATCATTGAATGAAACAATAAAGAACTCCAAACTGGAGGTTTCCTGTTGTGCT
CCATGGTTCCAGGATATTTTGCATTTGGAGTCACCTGAATCTGGTAACCACAGTACAAGTGTGCAGAGCTGGGCCTTCATTCCACAGGAC
ATAATGCATGGGCAATATAATGTTCTACAGAAAGATCATGCCAAGACCAGTGATCCAGGAAGATCATGGAAAATAATGCACATCAGTGAA
CAAGAGGAACCCATAGAGCTTAAATGTGTGTCTGTGACAGGATTCACTGCACTGTTTACTTGGGAAGTGGAAAGGATGGGCTATACCATT
ACCCTCTGGGATTTGGAGACCCAGGGCATGCAGTGTTTTTCCCTTGGCACAAAGTGTATTCCTGTAGACAGTAGTGGAGACCAGCAGCTG
TGCTTTGTTTTGACAGAGAATGGACTCTCTCTGATTTTGTTTGGTTTGACTCAAGAAGAGTTTTTAAACAGACTCATGATCCATGGAAGT
GCCAGCACTGTGGACACTCTTTGTCATCTCAATGGCTGGGGAAGGTGCTCAATTCCCATACATGCACTAGAGGCCGGGATAGAAAATCGT
CAGCTGGACACAGTAAATTTCTTTTTGAAGAGCAAGGAAAATCTTTTTAATCCATCCTCAAAATCTTCTGTATCTGATCAGTTTGATCAC
TTGTCATCCCATTTATATTTAAGAATCTATGGGGTGGAGCTGTTCCTGAAGGTTGCCGGCCTGGGCCCTGTGGAGTACTTGTCTTCCGGA
TGGAACTTGTTTGACTTCTCCGTGACAGTGTTCGCCTTCCTGGGACTGCTGGCGCTGGCCCTCAACATGGAGCCCTTCTATTTCATCGTG
GTCCTGCGCCCCCTCCAGCTGCTGAGGTTGTTTAAGTTGAAGGAGCGCTACCGCAACGTGCTGGACACCATGTTCGAGCTGCTGCCCCGG
ATGGCCAGCCTGGGCCTCACCCTGCTCATCTTTTACTACTCCTTCGCCATCGTGGGCATGGAGTTCTTCTGCGGGATCGTCTTCCCCAAC
TGCTGCAACACGAGTACAGTGGCAGATGCCTACCGCTGGCGCAACCACACCGTGGGCAACAGGACCGTGGTGGAGGAAGGCTACTATTAT
CTCAATAATTTTGACAACATCCTCAACAGCTTTGTGACCCTGTTTGAGCTCACAGTTGTCAACAACTGGTACATCATCATGGAAGGCGTC
ACCTCTCAGACCTCCCACTGGAGCCGCCTCTACTTCATGACCTTTTACATTGTGACCATGGTGGTGATGACGATCATTGTCGCCTTTATC
CTCGAGGCCTTCGTCTTCCGAATGAACTACAGCCGCAAGAACCAGGACTCGGAAGTTGATGGTGGCATCACCCTTGAGAAGGAAATCTCC
AAAGAAGAGCTGGTTGCCGTCCTGGAGCTCTACCGGGAGGCACGGGGGGCCTCCTCGGATGTCACCAGGCTGCTGGAGACCCTCTCCCAG
ATGGAGAGATACCAGCAACATTCCATGGTGTTTCTGGGACGGCGATCAAGGACCAAGAGCGACCTGAGCCTGAAGATGTACCAGGAGGAG
ATCCAGGAGTGGTATGAGGAGCATGCCAGGGAGCAAGAGCAGCAGCGACAACTCAGCAGCAGTGCAGCCCCCGCCGCCCAGCAGCCCCCA
GGCAGCCGCCAGCGCTCCCAGACCGTTACCTAGCCCAGCGCCCGAAAGCCGTCTCTTCTATGCAATAACACAATAGTATTACTCTACTGC
GATGTACGGAACTGCGGTGTGTGTACACATACTCACGTATATGCACATATTTATATACAGGAAGAAAAAAGACAGACAAGATGGGGCTTG
GTTTATAACCACCTTGCCCTGTCTTCCTTAACTCCAGAAGCCAGTTTGGTGAGGGGTGGGGGTGCGGCCACCAGGTCTGAGCTCTTCCTA
CTGTGGAAGGCTCCAGAAGGCCCTTCACAAGGAGACCCCTCACCTGGATCCAGTCGACTGCGGGGCTTGCCCCTCATGTGGGCTGGCCTC
CATCGGCCACGTCCAAAGCTGTCACTGCTACTGCTTCAGGCTCACATCCCCCCGACCTGATGGCGTGCCCGCCCCCTCTCCCTGCGGCCC
ATGCCACAGGTTTCTGTGTTTTGCTTTAGGGACAGAACCACTTAGGAAGGAAAGAACTCCCGGTCTCCAGGGTGGTATTTCAGTGTCTGT
GATAATGTCACGCAACACCTCTTCGGGGACCAGTGCCCAGGATCTAATGGAAGCGGAATTGGGGCAACTGGGCCCATGTGGCCAGAGCTC
AGTTAGCCAGTGCCGGGCGGCCACAGATTACACTGACCAATCTCCTCCCTTGGCTCTGCAAGCCTCCCACCCAGCCTTCTCTGGCTTAAC
CCTTGTTGGCGAAAACTCTTCCACAGTGGCCTCCTTGGGGACCCAGAACCCGGAGGAAGGGGCATGAGGCAGGAAGTGGGGCCGATGTCT
GCAACCCAGACCACTTCGTGGAATGGGCTCTTGACCAAATCCCTTTTTTTGCGATTTACCCGTTCAAGCAAAACAACGTTTTGGTTAACT
AAGGATTGTGCTAAAGCCGATACCAGGTCCTTCACACGTGTGCACTAGGAACAGGAGCGAACAGCACAGAGAGACGCTCCCTGTGGGACG
CAGCAGCCCCGTGGCCCCGGCCCAGTTCCCAGCCACCCTCCCTGGCTCTGCTCACACCAGAGATTTCCATAGCAGGAGCGGTTGGTGCAG
AAGTAGGTTCAGATGAACCTCAGTTAACGTCGCCACCCCTCCTCCCACCATGGTACCCTGTAGGAGCCCTGTATGACATCTGAGCGTGGT
GGAGGTAGGAGGGTTGCCAGCTGCAGTGACCCTGCCACAGAGGCAGGGTCAGTGCAGAGGTCGCTTTGGTTCCGCTTCCCTGGGCCACAG
AACGGAACACAGCATAGGTTCTGCAGCAGGAGCCGCAGTGGCAGGATGGAGGGTGCGAAGGGCAAGGAGTGCACTGCTGGGCATTCCTGG
CCAGCCCCGGCCCTCTGGTGCCTGCTTCCTGTGACTTCAGAAGGCAGGTGGACAGAGCCTCCCTCTGGCCTTGTCCTCTTCCCAGCCACA
GAACGGGCAGGGTGGCACCCGACCCCAGGGGAGCAGTACCTGGTCCCCCACCCCCTCCTCCCAACCACCTCCAAGGCCAAGCTGGGTCCC
ATAGCCAGCACGGCATGGTTCTCCCCTTCCCCCCTTCCCAGGTCAGGGGAGTTGGACAAGTAGCAGGTGTTTGTTTTTAAAGCACAGCCC
TTTGGGAAAGCAACACATTATTGAGACTCACTGTGATTCCCCCGGGAGTCAGACTGGCTTTGTCCTCTTCCTCTCTGGAGGGCCATGGGC
CATCAGCAGGAGCTCCACATCGAGCCCCAGGCCAGAACCCCCTCCCTTTCACAGAGAGGGAACTTTATTGCACAATTGGGTGCCTTTTAG
CTTTTGTGTGTTGAAATGGGCGTTTTGGAAGCAAGGGTCAGGGGACAGCTTCTAAAGGTGTGAGTCTCTGACCTGAGCATCTGGGCCTCG
CCTGGGCCCTTCTTCCTCCCCAGGGGTGGAAACGTGGAGGGGCCAGCAGCACCCCGGGGTCTGCCCAGGGGAGTCAAGGCCCCGAGGTGG
GGGGGCCTATTCCAGGAGGAGTGGGATCTCGGCCCTGTCCAGAGCGAGTTAATGTGTCCATCTGCCCAACCCTGTCCTGAGAAAGGACCT
GGTTTTGGCCAGGACCTGACAAATACCCAATGGCAGCAGTGTCAACAGACGGGAGTCCAGCCAGGGTGGGTGCCCTTGTCATTGAGGTTA
GGGACAGCTATCCCCAGGTTATGCCTGGCCCCACCCAGCAGGGAGTTGGGGTCCCCCCACAGGCTGTGAGCTCTGTGGGCCCTGGGATGT
GATCTAGCTCAGATGCCCTCTCATCCTTGATGTCATAGTTGAGTGCACCCAAGTGGCACCCACTGGCGGCCAGGGGCACAGCCTGGTGGT
GGTGGCAATAGAACTGTGCCCCTCCTCAGCTCCTCGCTTCCCCTCCCACAGCCCCAGCCTTACTCCACCATGCGGACAATCATTTTGTAC
GGATCACGGGAGCAATGCTGTACGGTTTTGTACACTGGTGGTTTGTTTCCTAGAAAACCCATTGTGTCTCTGGATTTCTAGCACATTACT

>85743_85743_7_SPG11-TPCN1_SPG11_chr15_44925703_ENST00000427534_TPCN1_chr12_113723694_ENST00000541517_length(amino acids)=910AA_BP=579
MAAEEGVASAASAGGSWGTAAMGRVLPMLLVPVPAEAMGQLGSRAQLRTQPEALGSLTAAGSLQVLSLTPGSRGGGRCCLEGPFWHFLWE
DSRNSSTPTEKPKLLALGENYELLIYEFNLKDGRCDATILYSCSREALQKLIDDQDISISLLSLRILSFHNNTSLLFINKCVILHIIFPE
RDAAIRVLNCFTLPLPAQAVDMIIDTQLCRGILFVLSSLGWIYIFDVVDGTYVAHVDLALHKEDMCNEQQQEPAKISSFTSLKVSQDLDV
AVIVSSSNSAVALNLNLYFRQHPGHLLCERILEDLPIQGPKGVDEDDPVNSAYNMKLAKFSFQIDRSWKAQLSSLNETIKNSKLEVSCCA
PWFQDILHLESPESGNHSTSVQSWAFIPQDIMHGQYNVLQKDHAKTSDPGRSWKIMHISEQEEPIELKCVSVTGFTALFTWEVERMGYTI
TLWDLETQGMQCFSLGTKCIPVDSSGDQQLCFVLTENGLSLILFGLTQEEFLNRLMIHGSASTVDTLCHLNGWGRCSIPIHALEAGIENR
QLDTVNFFLKSKENLFNPSSKSSVSDQFDHLSSHLYLRIYGVELFLKVAGLGPVEYLSSGWNLFDFSVTVFAFLGLLALALNMEPFYFIV
VLRPLQLLRLFKLKERYRNVLDTMFELLPRMASLGLTLLIFYYSFAIVGMEFFCGIVFPNCCNTSTVADAYRWRNHTVGNRTVVEEGYYY
LNNFDNILNSFVTLFELTVVNNWYIIMEGVTSQTSHWSRLYFMTFYIVTMVVMTIIVAFILEAFVFRMNYSRKNQDSEVDGGITLEKEIS
KEELVAVLELYREARGASSDVTRLLETLSQMERYQQHSMVFLGRRSRTKSDLSLKMYQEEIQEWYEEHAREQEQQRQLSSSAAPAAQQPP

--------------------------------------------------------------
>85743_85743_8_SPG11-TPCN1_SPG11_chr15_44925703_ENST00000427534_TPCN1_chr12_113723694_ENST00000550785_length(transcript)=5242nt_BP=1735nt
ATGGCTGCAGAGGAAGGGGTCGCGAGTGCTGCTTCCGCCGGCGGTAGCTGGGGCACCGCGGCCATGGGGCGGGTTCTACCGATGCTGTTG
GTGCCAGTCCCCGCCGAGGCGATGGGGCAGCTCGGCTCCCGGGCGCAGCTGCGCACACAGCCGGAGGCTCTGGGGAGCCTGACGGCTGCG
GGCAGCCTCCAAGTGCTTTCTTTGACGCCTGGCAGCCGGGGCGGGGGTCGCTGCTGCCTGGAGGGCCCCTTCTGGCACTTTCTATGGGAG
GATTCTCGTAACAGCAGCACACCAACTGAAAAGCCCAAACTGCTCGCTCTTGGTGAAAATTATGAACTGCTTATCTATGAATTTAATTTG
AAAGATGGAAGATGTGATGCAACCATTTTGTATAGCTGTAGTAGGGAGGCATTGCAAAAGCTCATTGACGATCAAGATATCAGTATTTCC
TTATTGTCTTTGAGAATCCTGTCATTTCACAATAACACATCATTACTGTTCATCAACAAATGTGTCATCCTACATATTATATTTCCTGAA
AGAGATGCTGCAATTAGAGTACTCAACTGTTTCACACTTCCCTTGCCTGCACAGGCAGTGGACATGATTATTGACACGCAGCTCTGCAGA
GGAATTCTTTTTGTTTTGAGTAGTTTAGGCTGGATCTACATTTTTGATGTTGTGGATGGTACATATGTAGCTCATGTGGATTTAGCACTT
CACAAAGAAGACATGTGTAATGAGCAGCAACAGGAGCCAGCCAAGATTTCTTCATTTACTTCACTGAAAGTTTCTCAAGACCTCGATGTT
GCAGTGATTGTCAGCTCCTCCAACTCCGCAGTTGCTCTTAACTTAAATTTGTATTTCAGGCAACACCCAGGACACCTACTGTGTGAAAGA
ATACTAGAAGATCTTCCTATTCAAGGACCTAAGGGCGTAGATGAAGATGATCCTGTTAACTCTGCCTACAACATGAAACTGGCCAAGTTT
TCCTTCCAAATTGATAGGTCTTGGAAAGCCCAGCTATCATCATTGAATGAAACAATAAAGAACTCCAAACTGGAGGTTTCCTGTTGTGCT
CCATGGTTCCAGGATATTTTGCATTTGGAGTCACCTGAATCTGGTAACCACAGTACAAGTGTGCAGAGCTGGGCCTTCATTCCACAGGAC
ATAATGCATGGGCAATATAATGTTCTACAGAAAGATCATGCCAAGACCAGTGATCCAGGAAGATCATGGAAAATAATGCACATCAGTGAA
CAAGAGGAACCCATAGAGCTTAAATGTGTGTCTGTGACAGGATTCACTGCACTGTTTACTTGGGAAGTGGAAAGGATGGGCTATACCATT
ACCCTCTGGGATTTGGAGACCCAGGGCATGCAGTGTTTTTCCCTTGGCACAAAGTGTATTCCTGTAGACAGTAGTGGAGACCAGCAGCTG
TGCTTTGTTTTGACAGAGAATGGACTCTCTCTGATTTTGTTTGGTTTGACTCAAGAAGAGTTTTTAAACAGACTCATGATCCATGGAAGT
GCCAGCACTGTGGACACTCTTTGTCATCTCAATGGCTGGGGAAGGTGCTCAATTCCCATACATGCACTAGAGGCCGGGATAGAAAATCGT
CAGCTGGACACAGTAAATTTCTTTTTGAAGAGCAAGGAAAATCTTTTTAATCCATCCTCAAAATCTTCTGTATCTGATCAGTTTGATCAC
TTGTCATCCCATTTATATTTAAGAATCTATGGGGTGGAGCTGTTCCTGAAGGTTGCCGGCCTGGGCCCTGTGGAGTACTTGTCTTCCGGA
TGGAACTTGTTTGACTTCTCCGTGACAGTGTTCGCCTTCCTGGGACTGCTGGCGCTGGCCCTCAACATGGAGCCCTTCTATTTCATCGTG
GTCCTGCGCCCCCTCCAGCTGCTGAGGTTGTTTAAGTTGAAGGAGCGCTACCGCAACGTGCTGGACACCATGTTCGAGCTGCTGCCCCGG
ATGGCCAGCCTGGGCCTCACCCTGCTCATCTTTTACTACTCCTTCGCCATCGTGGGCATGGAGTTCTTCTGCGGGATCGTCTTCCCCAAC
TGCTGCAACACGAGTACAGTGGCAGATGCCTACCGCTGGCGCAACCACACCGTGGGCAACAGGACCGTGGTGGAGGAAGGCTACTATTAT
CTCAATAATTTTGACAACATCCTCAACAGCTTTGTGACCCTGTTTGAGCTCACAGTTGTCAACAACTGGTACATCATCATGGAAGGCGTC
ACCTCTCAGACCTCCCACTGGAGCCGCCTCTACTTCATGACCTTTTACATTGTGACCATGGTGGTGATGACGATCATTGTCGCCTTTATC
CTCGAGGCCTTCGTCTTCCGAATGAACTACAGCCGCAAGAACCAGGACTCGGAAGTTGATGGTGGCATCACCCTTGAGAAGGAAATCTCC
AAAGAAGAGCTGGTTGCCGTCCTGGAGCTCTACCGGGAGGCACGGGGGGCCTCCTCGGATGTCACCAGGCTGCTGGAGACCCTCTCCCAG
ATGGAGAGATACCAGCAACATTCCATGGTGTTTCTGGGACGGCGATCAAGGACCAAGAGCGACCTGAGCCTGAAGATGTACCAGGAGGAG
ATCCAGGAGTGGTATGAGGAGCATGCCAGGGAGCAAGAGCAGCAGCGACAACTCAGCAGCAGTGCAGCCCCCGCCGCCCAGCAGCCCCCA
GGCAGCCGCCAGCGCTCCCAGACCGTTACCTAGCCCAGCGCCCGAAAGCCGTCTCTTCTATGCAATAACACAATAGTATTACTCTACTGC
GATGTACGGAACTGCGGTGTGTGTACACATACTCACGTATATGCACATATTTATATACAGGAAGAAAAAAGACAGACAAGATGGGGCTTG
GTTTATAACCACCTTGCCCTGTCTTCCTTAACTCCAGAAGCCAGTTTGGTGAGGGGTGGGGGTGCGGCCACCAGGTCTGAGCTCTTCCTA
CTGTGGAAGGCTCCAGAAGGCCCTTCACAAGGAGACCCCTCACCTGGATCCAGTCGACTGCGGGGCTTGCCCCTCATGTGGGCTGGCCTC
CATCGGCCACGTCCAAAGCTGTCACTGCTACTGCTTCAGGCTCACATCCCCCCGACCTGATGGCGTGCCCGCCCCCTCTCCCTGCGGCCC
ATGCCACAGGTTTCTGTGTTTTGCTTTAGGGACAGAACCACTTAGGAAGGAAAGAACTCCCGGTCTCCAGGGTGGTATTTCAGTGTCTGT
GATAATGTCACGCAACACCTCTTCGGGGACCAGTGCCCAGGATCTAATGGAAGCGGAATTGGGGCAACTGGGCCCATGTGGCCAGAGCTC
AGTTAGCCAGTGCCGGGCGGCCACAGATTACACTGACCAATCTCCTCCCTTGGCTCTGCAAGCCTCCCACCCAGCCTTCTCTGGCTTAAC
CCTTGTTGGCGAAAACTCTTCCACAGTGGCCTCCTTGGGGACCCAGAACCCGGAGGAAGGGGCATGAGGCAGGAAGTGGGGCCGATGTCT
GCAACCCAGACCACTTCGTGGAATGGGCTCTTGACCAAATCCCTTTTTTTGCGATTTACCCGTTCAAGCAAAACAACGTTTTGGTTAACT
AAGGATTGTGCTAAAGCCGATACCAGGTCCTTCACACGTGTGCACTAGGAACAGGAGCGAACAGCACAGAGAGACGCTCCCTGTGGGACG
CAGCAGCCCCGTGGCCCCGGCCCAGTTCCCAGCCACCCTCCCTGGCTCTGCTCACACCAGAGATTTCCATAGCAGGAGCGGTTGGTGCAG
AAGTAGGTTCAGATGAACCTCAGTTAACGTCGCCACCCCTCCTCCCACCATGGTACCCTGTAGGAGCCCTGTATGACATCTGAGCGTGGT
GGAGGTAGGAGGGTTGCCAGCTGCAGTGACCCTGCCACAGAGGCAGGGTCAGTGCAGAGGTCGCTTTGGTTCCGCTTCCCTGGGCCACAG
AACGGAACACAGCATAGGTTCTGCAGCAGGAGCCGCAGTGGCAGGATGGAGGGTGCGAAGGGCAAGGAGTGCACTGCTGGGCATTCCTGG
CCAGCCCCGGCCCTCTGGTGCCTGCTTCCTGTGACTTCAGAAGGCAGGTGGACAGAGCCTCCCTCTGGCCTTGTCCTCTTCCCAGCCACA
GAACGGGCAGGGTGGCACCCGACCCCAGGGGAGCAGTACCTGGTCCCCCACCCCCTCCTCCCAACCACCTCCAAGGCCAAGCTGGGTCCC
ATAGCCAGCACGGCATGGTTCTCCCCTTCCCCCCTTCCCAGGTCAGGGGAGTTGGACAAGTAGCAGGTGTTTGTTTTTAAAGCACAGCCC
TTTGGGAAAGCAACACATTATTGAGACTCACTGTGATTCCCCCGGGAGTCAGACTGGCTTTGTCCTCTTCCTCTCTGGAGGGCCATGGGC
CATCAGCAGGAGCTCCACATCGAGCCCCAGGCCAGAACCCCCTCCCTTTCACAGAGAGGGAACTTTATTGCACAATTGGGTGCCTTTTAG
CTTTTGTGTGTTGAAATGGGCGTTTTGGAAGCAAGGGTCAGGGGACAGCTTCTAAAGGTGTGAGTCTCTGACCTGAGCATCTGGGCCTCG
CCTGGGCCCTTCTTCCTCCCCAGGGGTGGAAACGTGGAGGGGCCAGCAGCACCCCGGGGTCTGCCCAGGGGAGTCAAGGCCCCGAGGTGG
GGGGGCCTATTCCAGGAGGAGTGGGATCTCGGCCCTGTCCAGAGCGAGTTAATGTGTCCATCTGCCCAACCCTGTCCTGAGAAAGGACCT
GGTTTTGGCCAGGACCTGACAAATACCCAATGGCAGCAGTGTCAACAGACGGGAGTCCAGCCAGGGTGGGTGCCCTTGTCATTGAGGTTA
GGGACAGCTATCCCCAGGTTATGCCTGGCCCCACCCAGCAGGGAGTTGGGGTCCCCCCACAGGCTGTGAGCTCTGTGGGCCCTGGGATGT
GATCTAGCTCAGATGCCCTCTCATCCTTGATGTCATAGTTGAGTGCACCCAAGTGGCACCCACTGGCGGCCAGGGGCACAGCCTGGTGGT
GGTGGCAATAGAACTGTGCCCCTCCTCAGCTCCTCGCTTCCCCTCCCACAGCCCCAGCCTTACTCCACCATGCGGACAATCATTTTGTAC
GGATCACGGGAGCAATGCTGTACGGTTTTGTACACTGGTGGTTTGTTTCCTAGAAAACCCATTGTGTCTCTGGATTTCTAGCACATTACT

>85743_85743_8_SPG11-TPCN1_SPG11_chr15_44925703_ENST00000427534_TPCN1_chr12_113723694_ENST00000550785_length(amino acids)=910AA_BP=579
MAAEEGVASAASAGGSWGTAAMGRVLPMLLVPVPAEAMGQLGSRAQLRTQPEALGSLTAAGSLQVLSLTPGSRGGGRCCLEGPFWHFLWE
DSRNSSTPTEKPKLLALGENYELLIYEFNLKDGRCDATILYSCSREALQKLIDDQDISISLLSLRILSFHNNTSLLFINKCVILHIIFPE
RDAAIRVLNCFTLPLPAQAVDMIIDTQLCRGILFVLSSLGWIYIFDVVDGTYVAHVDLALHKEDMCNEQQQEPAKISSFTSLKVSQDLDV
AVIVSSSNSAVALNLNLYFRQHPGHLLCERILEDLPIQGPKGVDEDDPVNSAYNMKLAKFSFQIDRSWKAQLSSLNETIKNSKLEVSCCA
PWFQDILHLESPESGNHSTSVQSWAFIPQDIMHGQYNVLQKDHAKTSDPGRSWKIMHISEQEEPIELKCVSVTGFTALFTWEVERMGYTI
TLWDLETQGMQCFSLGTKCIPVDSSGDQQLCFVLTENGLSLILFGLTQEEFLNRLMIHGSASTVDTLCHLNGWGRCSIPIHALEAGIENR
QLDTVNFFLKSKENLFNPSSKSSVSDQFDHLSSHLYLRIYGVELFLKVAGLGPVEYLSSGWNLFDFSVTVFAFLGLLALALNMEPFYFIV
VLRPLQLLRLFKLKERYRNVLDTMFELLPRMASLGLTLLIFYYSFAIVGMEFFCGIVFPNCCNTSTVADAYRWRNHTVGNRTVVEEGYYY
LNNFDNILNSFVTLFELTVVNNWYIIMEGVTSQTSHWSRLYFMTFYIVTMVVMTIIVAFILEAFVFRMNYSRKNQDSEVDGGITLEKEIS
KEELVAVLELYREARGASSDVTRLLETLSQMERYQQHSMVFLGRRSRTKSDLSLKMYQEEIQEWYEEHAREQEQQRQLSSSAAPAAQQPP

--------------------------------------------------------------
>85743_85743_9_SPG11-TPCN1_SPG11_chr15_44925703_ENST00000535302_TPCN1_chr12_113723694_ENST00000335509_length(transcript)=5270nt_BP=1763nt
AGTGACCGGAAGTAACCGCCGGGCCAAGATGGCTGCAGAGGAAGGGGTCGCGAGTGCTGCTTCCGCCGGCGGTAGCTGGGGCACCGCGGC
CATGGGGCGGGTTCTACCGATGCTGTTGGTGCCAGTCCCCGCCGAGGCGATGGGGCAGCTCGGCTCCCGGGCGCAGCTGCGCACACAGCC
GGAGGCTCTGGGGAGCCTGACGGCTGCGGGCAGCCTCCAAGTGCTTTCTTTGACGCCTGGCAGCCGGGGCGGGGGTCGCTGCTGCCTGGA
GGGCCCCTTCTGGCACTTTCTATGGGAGGATTCTCGTAACAGCAGCACACCAACTGAAAAGCCCAAACTGCTCGCTCTTGGTGAAAATTA
TGAACTGCTTATCTATGAATTTAATTTGAAAGATGGAAGATGTGATGCAACCATTTTGTATAGCTGTAGTAGGGAGGCATTGCAAAAGCT
CATTGACGATCAAGATATCAGTATTTCCTTATTGTCTTTGAGAATCCTGTCATTTCACAATAACACATCATTACTGTTCATCAACAAATG
TGTCATCCTACATATTATATTTCCTGAAAGAGATGCTGCAATTAGAGTACTCAACTGTTTCACACTTCCCTTGCCTGCACAGGCAGTGGA
CATGATTATTGACACGCAGCTCTGCAGAGGAATTCTTTTTGTTTTGAGTAGTTTAGGCTGGATCTACATTTTTGATGTTGTGGATGGTAC
ATATGTAGCTCATGTGGATTTAGCACTTCACAAAGAAGACATGTGTAATGAGCAGCAACAGGAGCCAGCCAAGATTTCTTCATTTACTTC
ACTGAAAGTTTCTCAAGACCTCGATGTTGCAGTGATTGTCAGCTCCTCCAACTCCGCAGTTGCTCTTAACTTAAATTTGTATTTCAGGCA
ACACCCAGGACACCTACTGTGTGAAAGAATACTAGAAGATCTTCCTATTCAAGGACCTAAGGGCGTAGATGAAGATGATCCTGTTAACTC
TGCCTACAACATGAAACTGGCCAAGTTTTCCTTCCAAATTGATAGGTCTTGGAAAGCCCAGCTATCATCATTGAATGAAACAATAAAGAA
CTCCAAACTGGAGGTTTCCTGTTGTGCTCCATGGTTCCAGGATATTTTGCATTTGGAGTCACCTGAATCTGGTAACCACAGTACAAGTGT
GCAGAGCTGGGCCTTCATTCCACAGGACATAATGCATGGGCAATATAATGTTCTACAGAAAGATCATGCCAAGACCAGTGATCCAGGAAG
ATCATGGAAAATAATGCACATCAGTGAACAAGAGGAACCCATAGAGCTTAAATGTGTGTCTGTGACAGGATTCACTGCACTGTTTACTTG
GGAAGTGGAAAGGATGGGCTATACCATTACCCTCTGGGATTTGGAGACCCAGGGCATGCAGTGTTTTTCCCTTGGCACAAAGTGTATTCC
TGTAGACAGTAGTGGAGACCAGCAGCTGTGCTTTGTTTTGACAGAGAATGGACTCTCTCTGATTTTGTTTGGTTTGACTCAAGAAGAGTT
TTTAAACAGACTCATGATCCATGGAAGTGCCAGCACTGTGGACACTCTTTGTCATCTCAATGGCTGGGGAAGGTGCTCAATTCCCATACA
TGCACTAGAGGCCGGGATAGAAAATCGTCAGCTGGACACAGTAAATTTCTTTTTGAAGAGCAAGGAAAATCTTTTTAATCCATCCTCAAA
ATCTTCTGTATCTGATCAGTTTGATCACTTGTCATCCCATTTATATTTAAGAATCTATGGGGTGGAGCTGTTCCTGAAGGTTGCCGGCCT
GGGCCCTGTGGAGTACTTGTCTTCCGGATGGAACTTGTTTGACTTCTCCGTGACAGTGTTCGCCTTCCTGGGACTGCTGGCGCTGGCCCT
CAACATGGAGCCCTTCTATTTCATCGTGGTCCTGCGCCCCCTCCAGCTGCTGAGGTTGTTTAAGTTGAAGGAGCGCTACCGCAACGTGCT
GGACACCATGTTCGAGCTGCTGCCCCGGATGGCCAGCCTGGGCCTCACCCTGCTCATCTTTTACTACTCCTTCGCCATCGTGGGCATGGA
GTTCTTCTGCGGGATCGTCTTCCCCAACTGCTGCAACACGAGTACAGTGGCAGATGCCTACCGCTGGCGCAACCACACCGTGGGCAACAG
GACCGTGGTGGAGGAAGGCTACTATTATCTCAATAATTTTGACAACATCCTCAACAGCTTTGTGACCCTGTTTGAGCTCACAGTTGTCAA
CAACTGGTACATCATCATGGAAGGCGTCACCTCTCAGACCTCCCACTGGAGCCGCCTCTACTTCATGACCTTTTACATTGTGACCATGGT
GGTGATGACGATCATTGTCGCCTTTATCCTCGAGGCCTTCGTCTTCCGAATGAACTACAGCCGCAAGAACCAGGACTCGGAAGTTGATGG
TGGCATCACCCTTGAGAAGGAAATCTCCAAAGAAGAGCTGGTTGCCGTCCTGGAGCTCTACCGGGAGGCACGGGGGGCCTCCTCGGATGT
CACCAGGCTGCTGGAGACCCTCTCCCAGATGGAGAGATACCAGCAACATTCCATGGTGTTTCTGGGACGGCGATCAAGGACCAAGAGCGA
CCTGAGCCTGAAGATGTACCAGGAGGAGATCCAGGAGTGGTATGAGGAGCATGCCAGGGAGCAAGAGCAGCAGCGACAACTCAGCAGCAG
TGCAGCCCCCGCCGCCCAGCAGCCCCCAGGCAGCCGCCAGCGCTCCCAGACCGTTACCTAGCCCAGCGCCCGAAAGCCGTCTCTTCTATG
CAATAACACAATAGTATTACTCTACTGCGATGTACGGAACTGCGGTGTGTGTACACATACTCACGTATATGCACATATTTATATACAGGA
AGAAAAAAGACAGACAAGATGGGGCTTGGTTTATAACCACCTTGCCCTGTCTTCCTTAACTCCAGAAGCCAGTTTGGTGAGGGGTGGGGG
TGCGGCCACCAGGTCTGAGCTCTTCCTACTGTGGAAGGCTCCAGAAGGCCCTTCACAAGGAGACCCCTCACCTGGATCCAGTCGACTGCG
GGGCTTGCCCCTCATGTGGGCTGGCCTCCATCGGCCACGTCCAAAGCTGTCACTGCTACTGCTTCAGGCTCACATCCCCCCGACCTGATG
GCGTGCCCGCCCCCTCTCCCTGCGGCCCATGCCACAGGTTTCTGTGTTTTGCTTTAGGGACAGAACCACTTAGGAAGGAAAGAACTCCCG
GTCTCCAGGGTGGTATTTCAGTGTCTGTGATAATGTCACGCAACACCTCTTCGGGGACCAGTGCCCAGGATCTAATGGAAGCGGAATTGG
GGCAACTGGGCCCATGTGGCCAGAGCTCAGTTAGCCAGTGCCGGGCGGCCACAGATTACACTGACCAATCTCCTCCCTTGGCTCTGCAAG
CCTCCCACCCAGCCTTCTCTGGCTTAACCCTTGTTGGCGAAAACTCTTCCACAGTGGCCTCCTTGGGGACCCAGAACCCGGAGGAAGGGG
CATGAGGCAGGAAGTGGGGCCGATGTCTGCAACCCAGACCACTTCGTGGAATGGGCTCTTGACCAAATCCCTTTTTTTGCGATTTACCCG
TTCAAGCAAAACAACGTTTTGGTTAACTAAGGATTGTGCTAAAGCCGATACCAGGTCCTTCACACGTGTGCACTAGGAACAGGAGCGAAC
AGCACAGAGAGACGCTCCCTGTGGGACGCAGCAGCCCCGTGGCCCCGGCCCAGTTCCCAGCCACCCTCCCTGGCTCTGCTCACACCAGAG
ATTTCCATAGCAGGAGCGGTTGGTGCAGAAGTAGGTTCAGATGAACCTCAGTTAACGTCGCCACCCCTCCTCCCACCATGGTACCCTGTA
GGAGCCCTGTATGACATCTGAGCGTGGTGGAGGTAGGAGGGTTGCCAGCTGCAGTGACCCTGCCACAGAGGCAGGGTCAGTGCAGAGGTC
GCTTTGGTTCCGCTTCCCTGGGCCACAGAACGGAACACAGCATAGGTTCTGCAGCAGGAGCCGCAGTGGCAGGATGGAGGGTGCGAAGGG
CAAGGAGTGCACTGCTGGGCATTCCTGGCCAGCCCCGGCCCTCTGGTGCCTGCTTCCTGTGACTTCAGAAGGCAGGTGGACAGAGCCTCC
CTCTGGCCTTGTCCTCTTCCCAGCCACAGAACGGGCAGGGTGGCACCCGACCCCAGGGGAGCAGTACCTGGTCCCCCACCCCCTCCTCCC
AACCACCTCCAAGGCCAAGCTGGGTCCCATAGCCAGCACGGCATGGTTCTCCCCTTCCCCCCTTCCCAGGTCAGGGGAGTTGGACAAGTA
GCAGGTGTTTGTTTTTAAAGCACAGCCCTTTGGGAAAGCAACACATTATTGAGACTCACTGTGATTCCCCCGGGAGTCAGACTGGCTTTG
TCCTCTTCCTCTCTGGAGGGCCATGGGCCATCAGCAGGAGCTCCACATCGAGCCCCAGGCCAGAACCCCCTCCCTTTCACAGAGAGGGAA
CTTTATTGCACAATTGGGTGCCTTTTAGCTTTTGTGTGTTGAAATGGGCGTTTTGGAAGCAAGGGTCAGGGGACAGCTTCTAAAGGTGTG
AGTCTCTGACCTGAGCATCTGGGCCTCGCCTGGGCCCTTCTTCCTCCCCAGGGGTGGAAACGTGGAGGGGCCAGCAGCACCCCGGGGTCT
GCCCAGGGGAGTCAAGGCCCCGAGGTGGGGGGGCCTATTCCAGGAGGAGTGGGATCTCGGCCCTGTCCAGAGCGAGTTAATGTGTCCATC
TGCCCAACCCTGTCCTGAGAAAGGACCTGGTTTTGGCCAGGACCTGACAAATACCCAATGGCAGCAGTGTCAACAGACGGGAGTCCAGCC
AGGGTGGGTGCCCTTGTCATTGAGGTTAGGGACAGCTATCCCCAGGTTATGCCTGGCCCCACCCAGCAGGGAGTTGGGGTCCCCCCACAG
GCTGTGAGCTCTGTGGGCCCTGGGATGTGATCTAGCTCAGATGCCCTCTCATCCTTGATGTCATAGTTGAGTGCACCCAAGTGGCACCCA
CTGGCGGCCAGGGGCACAGCCTGGTGGTGGTGGCAATAGAACTGTGCCCCTCCTCAGCTCCTCGCTTCCCCTCCCACAGCCCCAGCCTTA
CTCCACCATGCGGACAATCATTTTGTACGGATCACGGGAGCAATGCTGTACGGTTTTGTACACTGGTGGTTTGTTTCCTAGAAAACCCAT

>85743_85743_9_SPG11-TPCN1_SPG11_chr15_44925703_ENST00000535302_TPCN1_chr12_113723694_ENST00000335509_length(amino acids)=910AA_BP=579
MAAEEGVASAASAGGSWGTAAMGRVLPMLLVPVPAEAMGQLGSRAQLRTQPEALGSLTAAGSLQVLSLTPGSRGGGRCCLEGPFWHFLWE
DSRNSSTPTEKPKLLALGENYELLIYEFNLKDGRCDATILYSCSREALQKLIDDQDISISLLSLRILSFHNNTSLLFINKCVILHIIFPE
RDAAIRVLNCFTLPLPAQAVDMIIDTQLCRGILFVLSSLGWIYIFDVVDGTYVAHVDLALHKEDMCNEQQQEPAKISSFTSLKVSQDLDV
AVIVSSSNSAVALNLNLYFRQHPGHLLCERILEDLPIQGPKGVDEDDPVNSAYNMKLAKFSFQIDRSWKAQLSSLNETIKNSKLEVSCCA
PWFQDILHLESPESGNHSTSVQSWAFIPQDIMHGQYNVLQKDHAKTSDPGRSWKIMHISEQEEPIELKCVSVTGFTALFTWEVERMGYTI
TLWDLETQGMQCFSLGTKCIPVDSSGDQQLCFVLTENGLSLILFGLTQEEFLNRLMIHGSASTVDTLCHLNGWGRCSIPIHALEAGIENR
QLDTVNFFLKSKENLFNPSSKSSVSDQFDHLSSHLYLRIYGVELFLKVAGLGPVEYLSSGWNLFDFSVTVFAFLGLLALALNMEPFYFIV
VLRPLQLLRLFKLKERYRNVLDTMFELLPRMASLGLTLLIFYYSFAIVGMEFFCGIVFPNCCNTSTVADAYRWRNHTVGNRTVVEEGYYY
LNNFDNILNSFVTLFELTVVNNWYIIMEGVTSQTSHWSRLYFMTFYIVTMVVMTIIVAFILEAFVFRMNYSRKNQDSEVDGGITLEKEIS
KEELVAVLELYREARGASSDVTRLLETLSQMERYQQHSMVFLGRRSRTKSDLSLKMYQEEIQEWYEEHAREQEQQRQLSSSAAPAAQQPP

--------------------------------------------------------------
>85743_85743_10_SPG11-TPCN1_SPG11_chr15_44925703_ENST00000535302_TPCN1_chr12_113723694_ENST00000392569_length(transcript)=2879nt_BP=1763nt
AGTGACCGGAAGTAACCGCCGGGCCAAGATGGCTGCAGAGGAAGGGGTCGCGAGTGCTGCTTCCGCCGGCGGTAGCTGGGGCACCGCGGC
CATGGGGCGGGTTCTACCGATGCTGTTGGTGCCAGTCCCCGCCGAGGCGATGGGGCAGCTCGGCTCCCGGGCGCAGCTGCGCACACAGCC
GGAGGCTCTGGGGAGCCTGACGGCTGCGGGCAGCCTCCAAGTGCTTTCTTTGACGCCTGGCAGCCGGGGCGGGGGTCGCTGCTGCCTGGA
GGGCCCCTTCTGGCACTTTCTATGGGAGGATTCTCGTAACAGCAGCACACCAACTGAAAAGCCCAAACTGCTCGCTCTTGGTGAAAATTA
TGAACTGCTTATCTATGAATTTAATTTGAAAGATGGAAGATGTGATGCAACCATTTTGTATAGCTGTAGTAGGGAGGCATTGCAAAAGCT
CATTGACGATCAAGATATCAGTATTTCCTTATTGTCTTTGAGAATCCTGTCATTTCACAATAACACATCATTACTGTTCATCAACAAATG
TGTCATCCTACATATTATATTTCCTGAAAGAGATGCTGCAATTAGAGTACTCAACTGTTTCACACTTCCCTTGCCTGCACAGGCAGTGGA
CATGATTATTGACACGCAGCTCTGCAGAGGAATTCTTTTTGTTTTGAGTAGTTTAGGCTGGATCTACATTTTTGATGTTGTGGATGGTAC
ATATGTAGCTCATGTGGATTTAGCACTTCACAAAGAAGACATGTGTAATGAGCAGCAACAGGAGCCAGCCAAGATTTCTTCATTTACTTC
ACTGAAAGTTTCTCAAGACCTCGATGTTGCAGTGATTGTCAGCTCCTCCAACTCCGCAGTTGCTCTTAACTTAAATTTGTATTTCAGGCA
ACACCCAGGACACCTACTGTGTGAAAGAATACTAGAAGATCTTCCTATTCAAGGACCTAAGGGCGTAGATGAAGATGATCCTGTTAACTC
TGCCTACAACATGAAACTGGCCAAGTTTTCCTTCCAAATTGATAGGTCTTGGAAAGCCCAGCTATCATCATTGAATGAAACAATAAAGAA
CTCCAAACTGGAGGTTTCCTGTTGTGCTCCATGGTTCCAGGATATTTTGCATTTGGAGTCACCTGAATCTGGTAACCACAGTACAAGTGT
GCAGAGCTGGGCCTTCATTCCACAGGACATAATGCATGGGCAATATAATGTTCTACAGAAAGATCATGCCAAGACCAGTGATCCAGGAAG
ATCATGGAAAATAATGCACATCAGTGAACAAGAGGAACCCATAGAGCTTAAATGTGTGTCTGTGACAGGATTCACTGCACTGTTTACTTG
GGAAGTGGAAAGGATGGGCTATACCATTACCCTCTGGGATTTGGAGACCCAGGGCATGCAGTGTTTTTCCCTTGGCACAAAGTGTATTCC
TGTAGACAGTAGTGGAGACCAGCAGCTGTGCTTTGTTTTGACAGAGAATGGACTCTCTCTGATTTTGTTTGGTTTGACTCAAGAAGAGTT
TTTAAACAGACTCATGATCCATGGAAGTGCCAGCACTGTGGACACTCTTTGTCATCTCAATGGCTGGGGAAGGTGCTCAATTCCCATACA
TGCACTAGAGGCCGGGATAGAAAATCGTCAGCTGGACACAGTAAATTTCTTTTTGAAGAGCAAGGAAAATCTTTTTAATCCATCCTCAAA
ATCTTCTGTATCTGATCAGTTTGATCACTTGTCATCCCATTTATATTTAAGAATCTATGGGGTGGAGCTGTTCCTGAAGGTTGCCGGCCT
GGGCCCTGTGGAGTACTTGTCTTCCGGATGGAACTTGTTTGACTTCTCCGTGACAGTGTTCGCCTTCCTGGGACTGCTGGCGCTGGCCCT
CAACATGGAGCCCTTCTATTTCATCGTGGTCCTGCGCCCCCTCCAGCTGCTGAGGTTGTTTAAGTTGAAGGAGCGCTACCGCAACGTGCT
GGACACCATGTTCGAGCTGCTGCCCCGGATGGCCAGCCTGGGCCTCACCCTGCTCATCTTTTACTACTCCTTCGCCATCGTGGGCATGGA
GTTCTTCTGCGGGATCGTCTTCCCCAACTGCTGCAACACGAGTACAGTGGCAGATGCCTACCGCTGGCGCAACCACACCGTGGGCAACAG
GACCGTGGTGGAGGAAGGCTACTATTATCTCAATAATTTTGACAACATCCTCAACAGCTTTGTGACCCTGTTTGAGCTCACAGTTGTCAA
CAACTGGTACATCATCATGGAAGGCGTCACCTCTCAGACCTCCCACTGGAGCCGCCTCTACTTCATGACCTTTTACATTGTGACCATGGT
GGTGATGACGATCATTGTCGCCTTTATCCTCGAGGCCTTCGTCTTCCGAATGAACTACAGCCGCAAGAACCAGGACTCGGAAGTTGATGG
TGGCATCACCCTTGAGAAGGAAATCTCCAAAGAAGAGCTGGTTGCCGTCCTGGAGCTCTACCGGGAGGCACGGGGGGCCTCCTCGGATGT
CACCAGGCTGCTGGAGACCCTCTCCCAGATGGAGAGATACCAGCAACATTCCATGGTGTTTCTGGGACGGCGATCAAGGACCAAGAGCGA
CCTGAGCCTGAAGATGTACCAGGAGGAGATCCAGGAGTGGTATGAGGAGCATGCCAGGGAGCAAGAGCAGCAGCGACAACTCAGCAGCAG
TGCAGCCCCCGCCGCCCAGCAGCCCCCAGGCAGCCGCCAGCGCTCCCAGACCGTTACCTAGCCCAGCGCCCGAAAGCCGTCTCTTCTATG

>85743_85743_10_SPG11-TPCN1_SPG11_chr15_44925703_ENST00000535302_TPCN1_chr12_113723694_ENST00000392569_length(amino acids)=910AA_BP=579
MAAEEGVASAASAGGSWGTAAMGRVLPMLLVPVPAEAMGQLGSRAQLRTQPEALGSLTAAGSLQVLSLTPGSRGGGRCCLEGPFWHFLWE
DSRNSSTPTEKPKLLALGENYELLIYEFNLKDGRCDATILYSCSREALQKLIDDQDISISLLSLRILSFHNNTSLLFINKCVILHIIFPE
RDAAIRVLNCFTLPLPAQAVDMIIDTQLCRGILFVLSSLGWIYIFDVVDGTYVAHVDLALHKEDMCNEQQQEPAKISSFTSLKVSQDLDV
AVIVSSSNSAVALNLNLYFRQHPGHLLCERILEDLPIQGPKGVDEDDPVNSAYNMKLAKFSFQIDRSWKAQLSSLNETIKNSKLEVSCCA
PWFQDILHLESPESGNHSTSVQSWAFIPQDIMHGQYNVLQKDHAKTSDPGRSWKIMHISEQEEPIELKCVSVTGFTALFTWEVERMGYTI
TLWDLETQGMQCFSLGTKCIPVDSSGDQQLCFVLTENGLSLILFGLTQEEFLNRLMIHGSASTVDTLCHLNGWGRCSIPIHALEAGIENR
QLDTVNFFLKSKENLFNPSSKSSVSDQFDHLSSHLYLRIYGVELFLKVAGLGPVEYLSSGWNLFDFSVTVFAFLGLLALALNMEPFYFIV
VLRPLQLLRLFKLKERYRNVLDTMFELLPRMASLGLTLLIFYYSFAIVGMEFFCGIVFPNCCNTSTVADAYRWRNHTVGNRTVVEEGYYY
LNNFDNILNSFVTLFELTVVNNWYIIMEGVTSQTSHWSRLYFMTFYIVTMVVMTIIVAFILEAFVFRMNYSRKNQDSEVDGGITLEKEIS
KEELVAVLELYREARGASSDVTRLLETLSQMERYQQHSMVFLGRRSRTKSDLSLKMYQEEIQEWYEEHAREQEQQRQLSSSAAPAAQQPP

--------------------------------------------------------------
>85743_85743_11_SPG11-TPCN1_SPG11_chr15_44925703_ENST00000535302_TPCN1_chr12_113723694_ENST00000541517_length(transcript)=5267nt_BP=1763nt
AGTGACCGGAAGTAACCGCCGGGCCAAGATGGCTGCAGAGGAAGGGGTCGCGAGTGCTGCTTCCGCCGGCGGTAGCTGGGGCACCGCGGC
CATGGGGCGGGTTCTACCGATGCTGTTGGTGCCAGTCCCCGCCGAGGCGATGGGGCAGCTCGGCTCCCGGGCGCAGCTGCGCACACAGCC
GGAGGCTCTGGGGAGCCTGACGGCTGCGGGCAGCCTCCAAGTGCTTTCTTTGACGCCTGGCAGCCGGGGCGGGGGTCGCTGCTGCCTGGA
GGGCCCCTTCTGGCACTTTCTATGGGAGGATTCTCGTAACAGCAGCACACCAACTGAAAAGCCCAAACTGCTCGCTCTTGGTGAAAATTA
TGAACTGCTTATCTATGAATTTAATTTGAAAGATGGAAGATGTGATGCAACCATTTTGTATAGCTGTAGTAGGGAGGCATTGCAAAAGCT
CATTGACGATCAAGATATCAGTATTTCCTTATTGTCTTTGAGAATCCTGTCATTTCACAATAACACATCATTACTGTTCATCAACAAATG
TGTCATCCTACATATTATATTTCCTGAAAGAGATGCTGCAATTAGAGTACTCAACTGTTTCACACTTCCCTTGCCTGCACAGGCAGTGGA
CATGATTATTGACACGCAGCTCTGCAGAGGAATTCTTTTTGTTTTGAGTAGTTTAGGCTGGATCTACATTTTTGATGTTGTGGATGGTAC
ATATGTAGCTCATGTGGATTTAGCACTTCACAAAGAAGACATGTGTAATGAGCAGCAACAGGAGCCAGCCAAGATTTCTTCATTTACTTC
ACTGAAAGTTTCTCAAGACCTCGATGTTGCAGTGATTGTCAGCTCCTCCAACTCCGCAGTTGCTCTTAACTTAAATTTGTATTTCAGGCA
ACACCCAGGACACCTACTGTGTGAAAGAATACTAGAAGATCTTCCTATTCAAGGACCTAAGGGCGTAGATGAAGATGATCCTGTTAACTC
TGCCTACAACATGAAACTGGCCAAGTTTTCCTTCCAAATTGATAGGTCTTGGAAAGCCCAGCTATCATCATTGAATGAAACAATAAAGAA
CTCCAAACTGGAGGTTTCCTGTTGTGCTCCATGGTTCCAGGATATTTTGCATTTGGAGTCACCTGAATCTGGTAACCACAGTACAAGTGT
GCAGAGCTGGGCCTTCATTCCACAGGACATAATGCATGGGCAATATAATGTTCTACAGAAAGATCATGCCAAGACCAGTGATCCAGGAAG
ATCATGGAAAATAATGCACATCAGTGAACAAGAGGAACCCATAGAGCTTAAATGTGTGTCTGTGACAGGATTCACTGCACTGTTTACTTG
GGAAGTGGAAAGGATGGGCTATACCATTACCCTCTGGGATTTGGAGACCCAGGGCATGCAGTGTTTTTCCCTTGGCACAAAGTGTATTCC
TGTAGACAGTAGTGGAGACCAGCAGCTGTGCTTTGTTTTGACAGAGAATGGACTCTCTCTGATTTTGTTTGGTTTGACTCAAGAAGAGTT
TTTAAACAGACTCATGATCCATGGAAGTGCCAGCACTGTGGACACTCTTTGTCATCTCAATGGCTGGGGAAGGTGCTCAATTCCCATACA
TGCACTAGAGGCCGGGATAGAAAATCGTCAGCTGGACACAGTAAATTTCTTTTTGAAGAGCAAGGAAAATCTTTTTAATCCATCCTCAAA
ATCTTCTGTATCTGATCAGTTTGATCACTTGTCATCCCATTTATATTTAAGAATCTATGGGGTGGAGCTGTTCCTGAAGGTTGCCGGCCT
GGGCCCTGTGGAGTACTTGTCTTCCGGATGGAACTTGTTTGACTTCTCCGTGACAGTGTTCGCCTTCCTGGGACTGCTGGCGCTGGCCCT
CAACATGGAGCCCTTCTATTTCATCGTGGTCCTGCGCCCCCTCCAGCTGCTGAGGTTGTTTAAGTTGAAGGAGCGCTACCGCAACGTGCT
GGACACCATGTTCGAGCTGCTGCCCCGGATGGCCAGCCTGGGCCTCACCCTGCTCATCTTTTACTACTCCTTCGCCATCGTGGGCATGGA
GTTCTTCTGCGGGATCGTCTTCCCCAACTGCTGCAACACGAGTACAGTGGCAGATGCCTACCGCTGGCGCAACCACACCGTGGGCAACAG
GACCGTGGTGGAGGAAGGCTACTATTATCTCAATAATTTTGACAACATCCTCAACAGCTTTGTGACCCTGTTTGAGCTCACAGTTGTCAA
CAACTGGTACATCATCATGGAAGGCGTCACCTCTCAGACCTCCCACTGGAGCCGCCTCTACTTCATGACCTTTTACATTGTGACCATGGT
GGTGATGACGATCATTGTCGCCTTTATCCTCGAGGCCTTCGTCTTCCGAATGAACTACAGCCGCAAGAACCAGGACTCGGAAGTTGATGG
TGGCATCACCCTTGAGAAGGAAATCTCCAAAGAAGAGCTGGTTGCCGTCCTGGAGCTCTACCGGGAGGCACGGGGGGCCTCCTCGGATGT
CACCAGGCTGCTGGAGACCCTCTCCCAGATGGAGAGATACCAGCAACATTCCATGGTGTTTCTGGGACGGCGATCAAGGACCAAGAGCGA
CCTGAGCCTGAAGATGTACCAGGAGGAGATCCAGGAGTGGTATGAGGAGCATGCCAGGGAGCAAGAGCAGCAGCGACAACTCAGCAGCAG
TGCAGCCCCCGCCGCCCAGCAGCCCCCAGGCAGCCGCCAGCGCTCCCAGACCGTTACCTAGCCCAGCGCCCGAAAGCCGTCTCTTCTATG
CAATAACACAATAGTATTACTCTACTGCGATGTACGGAACTGCGGTGTGTGTACACATACTCACGTATATGCACATATTTATATACAGGA
AGAAAAAAGACAGACAAGATGGGGCTTGGTTTATAACCACCTTGCCCTGTCTTCCTTAACTCCAGAAGCCAGTTTGGTGAGGGGTGGGGG
TGCGGCCACCAGGTCTGAGCTCTTCCTACTGTGGAAGGCTCCAGAAGGCCCTTCACAAGGAGACCCCTCACCTGGATCCAGTCGACTGCG
GGGCTTGCCCCTCATGTGGGCTGGCCTCCATCGGCCACGTCCAAAGCTGTCACTGCTACTGCTTCAGGCTCACATCCCCCCGACCTGATG
GCGTGCCCGCCCCCTCTCCCTGCGGCCCATGCCACAGGTTTCTGTGTTTTGCTTTAGGGACAGAACCACTTAGGAAGGAAAGAACTCCCG
GTCTCCAGGGTGGTATTTCAGTGTCTGTGATAATGTCACGCAACACCTCTTCGGGGACCAGTGCCCAGGATCTAATGGAAGCGGAATTGG
GGCAACTGGGCCCATGTGGCCAGAGCTCAGTTAGCCAGTGCCGGGCGGCCACAGATTACACTGACCAATCTCCTCCCTTGGCTCTGCAAG
CCTCCCACCCAGCCTTCTCTGGCTTAACCCTTGTTGGCGAAAACTCTTCCACAGTGGCCTCCTTGGGGACCCAGAACCCGGAGGAAGGGG
CATGAGGCAGGAAGTGGGGCCGATGTCTGCAACCCAGACCACTTCGTGGAATGGGCTCTTGACCAAATCCCTTTTTTTGCGATTTACCCG
TTCAAGCAAAACAACGTTTTGGTTAACTAAGGATTGTGCTAAAGCCGATACCAGGTCCTTCACACGTGTGCACTAGGAACAGGAGCGAAC
AGCACAGAGAGACGCTCCCTGTGGGACGCAGCAGCCCCGTGGCCCCGGCCCAGTTCCCAGCCACCCTCCCTGGCTCTGCTCACACCAGAG
ATTTCCATAGCAGGAGCGGTTGGTGCAGAAGTAGGTTCAGATGAACCTCAGTTAACGTCGCCACCCCTCCTCCCACCATGGTACCCTGTA
GGAGCCCTGTATGACATCTGAGCGTGGTGGAGGTAGGAGGGTTGCCAGCTGCAGTGACCCTGCCACAGAGGCAGGGTCAGTGCAGAGGTC
GCTTTGGTTCCGCTTCCCTGGGCCACAGAACGGAACACAGCATAGGTTCTGCAGCAGGAGCCGCAGTGGCAGGATGGAGGGTGCGAAGGG
CAAGGAGTGCACTGCTGGGCATTCCTGGCCAGCCCCGGCCCTCTGGTGCCTGCTTCCTGTGACTTCAGAAGGCAGGTGGACAGAGCCTCC
CTCTGGCCTTGTCCTCTTCCCAGCCACAGAACGGGCAGGGTGGCACCCGACCCCAGGGGAGCAGTACCTGGTCCCCCACCCCCTCCTCCC
AACCACCTCCAAGGCCAAGCTGGGTCCCATAGCCAGCACGGCATGGTTCTCCCCTTCCCCCCTTCCCAGGTCAGGGGAGTTGGACAAGTA
GCAGGTGTTTGTTTTTAAAGCACAGCCCTTTGGGAAAGCAACACATTATTGAGACTCACTGTGATTCCCCCGGGAGTCAGACTGGCTTTG
TCCTCTTCCTCTCTGGAGGGCCATGGGCCATCAGCAGGAGCTCCACATCGAGCCCCAGGCCAGAACCCCCTCCCTTTCACAGAGAGGGAA
CTTTATTGCACAATTGGGTGCCTTTTAGCTTTTGTGTGTTGAAATGGGCGTTTTGGAAGCAAGGGTCAGGGGACAGCTTCTAAAGGTGTG
AGTCTCTGACCTGAGCATCTGGGCCTCGCCTGGGCCCTTCTTCCTCCCCAGGGGTGGAAACGTGGAGGGGCCAGCAGCACCCCGGGGTCT
GCCCAGGGGAGTCAAGGCCCCGAGGTGGGGGGGCCTATTCCAGGAGGAGTGGGATCTCGGCCCTGTCCAGAGCGAGTTAATGTGTCCATC
TGCCCAACCCTGTCCTGAGAAAGGACCTGGTTTTGGCCAGGACCTGACAAATACCCAATGGCAGCAGTGTCAACAGACGGGAGTCCAGCC
AGGGTGGGTGCCCTTGTCATTGAGGTTAGGGACAGCTATCCCCAGGTTATGCCTGGCCCCACCCAGCAGGGAGTTGGGGTCCCCCCACAG
GCTGTGAGCTCTGTGGGCCCTGGGATGTGATCTAGCTCAGATGCCCTCTCATCCTTGATGTCATAGTTGAGTGCACCCAAGTGGCACCCA
CTGGCGGCCAGGGGCACAGCCTGGTGGTGGTGGCAATAGAACTGTGCCCCTCCTCAGCTCCTCGCTTCCCCTCCCACAGCCCCAGCCTTA
CTCCACCATGCGGACAATCATTTTGTACGGATCACGGGAGCAATGCTGTACGGTTTTGTACACTGGTGGTTTGTTTCCTAGAAAACCCAT

>85743_85743_11_SPG11-TPCN1_SPG11_chr15_44925703_ENST00000535302_TPCN1_chr12_113723694_ENST00000541517_length(amino acids)=910AA_BP=579
MAAEEGVASAASAGGSWGTAAMGRVLPMLLVPVPAEAMGQLGSRAQLRTQPEALGSLTAAGSLQVLSLTPGSRGGGRCCLEGPFWHFLWE
DSRNSSTPTEKPKLLALGENYELLIYEFNLKDGRCDATILYSCSREALQKLIDDQDISISLLSLRILSFHNNTSLLFINKCVILHIIFPE
RDAAIRVLNCFTLPLPAQAVDMIIDTQLCRGILFVLSSLGWIYIFDVVDGTYVAHVDLALHKEDMCNEQQQEPAKISSFTSLKVSQDLDV
AVIVSSSNSAVALNLNLYFRQHPGHLLCERILEDLPIQGPKGVDEDDPVNSAYNMKLAKFSFQIDRSWKAQLSSLNETIKNSKLEVSCCA
PWFQDILHLESPESGNHSTSVQSWAFIPQDIMHGQYNVLQKDHAKTSDPGRSWKIMHISEQEEPIELKCVSVTGFTALFTWEVERMGYTI
TLWDLETQGMQCFSLGTKCIPVDSSGDQQLCFVLTENGLSLILFGLTQEEFLNRLMIHGSASTVDTLCHLNGWGRCSIPIHALEAGIENR
QLDTVNFFLKSKENLFNPSSKSSVSDQFDHLSSHLYLRIYGVELFLKVAGLGPVEYLSSGWNLFDFSVTVFAFLGLLALALNMEPFYFIV
VLRPLQLLRLFKLKERYRNVLDTMFELLPRMASLGLTLLIFYYSFAIVGMEFFCGIVFPNCCNTSTVADAYRWRNHTVGNRTVVEEGYYY
LNNFDNILNSFVTLFELTVVNNWYIIMEGVTSQTSHWSRLYFMTFYIVTMVVMTIIVAFILEAFVFRMNYSRKNQDSEVDGGITLEKEIS
KEELVAVLELYREARGASSDVTRLLETLSQMERYQQHSMVFLGRRSRTKSDLSLKMYQEEIQEWYEEHAREQEQQRQLSSSAAPAAQQPP

--------------------------------------------------------------
>85743_85743_12_SPG11-TPCN1_SPG11_chr15_44925703_ENST00000535302_TPCN1_chr12_113723694_ENST00000550785_length(transcript)=5270nt_BP=1763nt
AGTGACCGGAAGTAACCGCCGGGCCAAGATGGCTGCAGAGGAAGGGGTCGCGAGTGCTGCTTCCGCCGGCGGTAGCTGGGGCACCGCGGC
CATGGGGCGGGTTCTACCGATGCTGTTGGTGCCAGTCCCCGCCGAGGCGATGGGGCAGCTCGGCTCCCGGGCGCAGCTGCGCACACAGCC
GGAGGCTCTGGGGAGCCTGACGGCTGCGGGCAGCCTCCAAGTGCTTTCTTTGACGCCTGGCAGCCGGGGCGGGGGTCGCTGCTGCCTGGA
GGGCCCCTTCTGGCACTTTCTATGGGAGGATTCTCGTAACAGCAGCACACCAACTGAAAAGCCCAAACTGCTCGCTCTTGGTGAAAATTA
TGAACTGCTTATCTATGAATTTAATTTGAAAGATGGAAGATGTGATGCAACCATTTTGTATAGCTGTAGTAGGGAGGCATTGCAAAAGCT
CATTGACGATCAAGATATCAGTATTTCCTTATTGTCTTTGAGAATCCTGTCATTTCACAATAACACATCATTACTGTTCATCAACAAATG
TGTCATCCTACATATTATATTTCCTGAAAGAGATGCTGCAATTAGAGTACTCAACTGTTTCACACTTCCCTTGCCTGCACAGGCAGTGGA
CATGATTATTGACACGCAGCTCTGCAGAGGAATTCTTTTTGTTTTGAGTAGTTTAGGCTGGATCTACATTTTTGATGTTGTGGATGGTAC
ATATGTAGCTCATGTGGATTTAGCACTTCACAAAGAAGACATGTGTAATGAGCAGCAACAGGAGCCAGCCAAGATTTCTTCATTTACTTC
ACTGAAAGTTTCTCAAGACCTCGATGTTGCAGTGATTGTCAGCTCCTCCAACTCCGCAGTTGCTCTTAACTTAAATTTGTATTTCAGGCA
ACACCCAGGACACCTACTGTGTGAAAGAATACTAGAAGATCTTCCTATTCAAGGACCTAAGGGCGTAGATGAAGATGATCCTGTTAACTC
TGCCTACAACATGAAACTGGCCAAGTTTTCCTTCCAAATTGATAGGTCTTGGAAAGCCCAGCTATCATCATTGAATGAAACAATAAAGAA
CTCCAAACTGGAGGTTTCCTGTTGTGCTCCATGGTTCCAGGATATTTTGCATTTGGAGTCACCTGAATCTGGTAACCACAGTACAAGTGT
GCAGAGCTGGGCCTTCATTCCACAGGACATAATGCATGGGCAATATAATGTTCTACAGAAAGATCATGCCAAGACCAGTGATCCAGGAAG
ATCATGGAAAATAATGCACATCAGTGAACAAGAGGAACCCATAGAGCTTAAATGTGTGTCTGTGACAGGATTCACTGCACTGTTTACTTG
GGAAGTGGAAAGGATGGGCTATACCATTACCCTCTGGGATTTGGAGACCCAGGGCATGCAGTGTTTTTCCCTTGGCACAAAGTGTATTCC
TGTAGACAGTAGTGGAGACCAGCAGCTGTGCTTTGTTTTGACAGAGAATGGACTCTCTCTGATTTTGTTTGGTTTGACTCAAGAAGAGTT
TTTAAACAGACTCATGATCCATGGAAGTGCCAGCACTGTGGACACTCTTTGTCATCTCAATGGCTGGGGAAGGTGCTCAATTCCCATACA
TGCACTAGAGGCCGGGATAGAAAATCGTCAGCTGGACACAGTAAATTTCTTTTTGAAGAGCAAGGAAAATCTTTTTAATCCATCCTCAAA
ATCTTCTGTATCTGATCAGTTTGATCACTTGTCATCCCATTTATATTTAAGAATCTATGGGGTGGAGCTGTTCCTGAAGGTTGCCGGCCT
GGGCCCTGTGGAGTACTTGTCTTCCGGATGGAACTTGTTTGACTTCTCCGTGACAGTGTTCGCCTTCCTGGGACTGCTGGCGCTGGCCCT
CAACATGGAGCCCTTCTATTTCATCGTGGTCCTGCGCCCCCTCCAGCTGCTGAGGTTGTTTAAGTTGAAGGAGCGCTACCGCAACGTGCT
GGACACCATGTTCGAGCTGCTGCCCCGGATGGCCAGCCTGGGCCTCACCCTGCTCATCTTTTACTACTCCTTCGCCATCGTGGGCATGGA
GTTCTTCTGCGGGATCGTCTTCCCCAACTGCTGCAACACGAGTACAGTGGCAGATGCCTACCGCTGGCGCAACCACACCGTGGGCAACAG
GACCGTGGTGGAGGAAGGCTACTATTATCTCAATAATTTTGACAACATCCTCAACAGCTTTGTGACCCTGTTTGAGCTCACAGTTGTCAA
CAACTGGTACATCATCATGGAAGGCGTCACCTCTCAGACCTCCCACTGGAGCCGCCTCTACTTCATGACCTTTTACATTGTGACCATGGT
GGTGATGACGATCATTGTCGCCTTTATCCTCGAGGCCTTCGTCTTCCGAATGAACTACAGCCGCAAGAACCAGGACTCGGAAGTTGATGG
TGGCATCACCCTTGAGAAGGAAATCTCCAAAGAAGAGCTGGTTGCCGTCCTGGAGCTCTACCGGGAGGCACGGGGGGCCTCCTCGGATGT
CACCAGGCTGCTGGAGACCCTCTCCCAGATGGAGAGATACCAGCAACATTCCATGGTGTTTCTGGGACGGCGATCAAGGACCAAGAGCGA
CCTGAGCCTGAAGATGTACCAGGAGGAGATCCAGGAGTGGTATGAGGAGCATGCCAGGGAGCAAGAGCAGCAGCGACAACTCAGCAGCAG
TGCAGCCCCCGCCGCCCAGCAGCCCCCAGGCAGCCGCCAGCGCTCCCAGACCGTTACCTAGCCCAGCGCCCGAAAGCCGTCTCTTCTATG
CAATAACACAATAGTATTACTCTACTGCGATGTACGGAACTGCGGTGTGTGTACACATACTCACGTATATGCACATATTTATATACAGGA
AGAAAAAAGACAGACAAGATGGGGCTTGGTTTATAACCACCTTGCCCTGTCTTCCTTAACTCCAGAAGCCAGTTTGGTGAGGGGTGGGGG
TGCGGCCACCAGGTCTGAGCTCTTCCTACTGTGGAAGGCTCCAGAAGGCCCTTCACAAGGAGACCCCTCACCTGGATCCAGTCGACTGCG
GGGCTTGCCCCTCATGTGGGCTGGCCTCCATCGGCCACGTCCAAAGCTGTCACTGCTACTGCTTCAGGCTCACATCCCCCCGACCTGATG
GCGTGCCCGCCCCCTCTCCCTGCGGCCCATGCCACAGGTTTCTGTGTTTTGCTTTAGGGACAGAACCACTTAGGAAGGAAAGAACTCCCG
GTCTCCAGGGTGGTATTTCAGTGTCTGTGATAATGTCACGCAACACCTCTTCGGGGACCAGTGCCCAGGATCTAATGGAAGCGGAATTGG
GGCAACTGGGCCCATGTGGCCAGAGCTCAGTTAGCCAGTGCCGGGCGGCCACAGATTACACTGACCAATCTCCTCCCTTGGCTCTGCAAG
CCTCCCACCCAGCCTTCTCTGGCTTAACCCTTGTTGGCGAAAACTCTTCCACAGTGGCCTCCTTGGGGACCCAGAACCCGGAGGAAGGGG
CATGAGGCAGGAAGTGGGGCCGATGTCTGCAACCCAGACCACTTCGTGGAATGGGCTCTTGACCAAATCCCTTTTTTTGCGATTTACCCG
TTCAAGCAAAACAACGTTTTGGTTAACTAAGGATTGTGCTAAAGCCGATACCAGGTCCTTCACACGTGTGCACTAGGAACAGGAGCGAAC
AGCACAGAGAGACGCTCCCTGTGGGACGCAGCAGCCCCGTGGCCCCGGCCCAGTTCCCAGCCACCCTCCCTGGCTCTGCTCACACCAGAG
ATTTCCATAGCAGGAGCGGTTGGTGCAGAAGTAGGTTCAGATGAACCTCAGTTAACGTCGCCACCCCTCCTCCCACCATGGTACCCTGTA
GGAGCCCTGTATGACATCTGAGCGTGGTGGAGGTAGGAGGGTTGCCAGCTGCAGTGACCCTGCCACAGAGGCAGGGTCAGTGCAGAGGTC
GCTTTGGTTCCGCTTCCCTGGGCCACAGAACGGAACACAGCATAGGTTCTGCAGCAGGAGCCGCAGTGGCAGGATGGAGGGTGCGAAGGG
CAAGGAGTGCACTGCTGGGCATTCCTGGCCAGCCCCGGCCCTCTGGTGCCTGCTTCCTGTGACTTCAGAAGGCAGGTGGACAGAGCCTCC
CTCTGGCCTTGTCCTCTTCCCAGCCACAGAACGGGCAGGGTGGCACCCGACCCCAGGGGAGCAGTACCTGGTCCCCCACCCCCTCCTCCC
AACCACCTCCAAGGCCAAGCTGGGTCCCATAGCCAGCACGGCATGGTTCTCCCCTTCCCCCCTTCCCAGGTCAGGGGAGTTGGACAAGTA
GCAGGTGTTTGTTTTTAAAGCACAGCCCTTTGGGAAAGCAACACATTATTGAGACTCACTGTGATTCCCCCGGGAGTCAGACTGGCTTTG
TCCTCTTCCTCTCTGGAGGGCCATGGGCCATCAGCAGGAGCTCCACATCGAGCCCCAGGCCAGAACCCCCTCCCTTTCACAGAGAGGGAA
CTTTATTGCACAATTGGGTGCCTTTTAGCTTTTGTGTGTTGAAATGGGCGTTTTGGAAGCAAGGGTCAGGGGACAGCTTCTAAAGGTGTG
AGTCTCTGACCTGAGCATCTGGGCCTCGCCTGGGCCCTTCTTCCTCCCCAGGGGTGGAAACGTGGAGGGGCCAGCAGCACCCCGGGGTCT
GCCCAGGGGAGTCAAGGCCCCGAGGTGGGGGGGCCTATTCCAGGAGGAGTGGGATCTCGGCCCTGTCCAGAGCGAGTTAATGTGTCCATC
TGCCCAACCCTGTCCTGAGAAAGGACCTGGTTTTGGCCAGGACCTGACAAATACCCAATGGCAGCAGTGTCAACAGACGGGAGTCCAGCC
AGGGTGGGTGCCCTTGTCATTGAGGTTAGGGACAGCTATCCCCAGGTTATGCCTGGCCCCACCCAGCAGGGAGTTGGGGTCCCCCCACAG
GCTGTGAGCTCTGTGGGCCCTGGGATGTGATCTAGCTCAGATGCCCTCTCATCCTTGATGTCATAGTTGAGTGCACCCAAGTGGCACCCA
CTGGCGGCCAGGGGCACAGCCTGGTGGTGGTGGCAATAGAACTGTGCCCCTCCTCAGCTCCTCGCTTCCCCTCCCACAGCCCCAGCCTTA
CTCCACCATGCGGACAATCATTTTGTACGGATCACGGGAGCAATGCTGTACGGTTTTGTACACTGGTGGTTTGTTTCCTAGAAAACCCAT

>85743_85743_12_SPG11-TPCN1_SPG11_chr15_44925703_ENST00000535302_TPCN1_chr12_113723694_ENST00000550785_length(amino acids)=910AA_BP=579
MAAEEGVASAASAGGSWGTAAMGRVLPMLLVPVPAEAMGQLGSRAQLRTQPEALGSLTAAGSLQVLSLTPGSRGGGRCCLEGPFWHFLWE
DSRNSSTPTEKPKLLALGENYELLIYEFNLKDGRCDATILYSCSREALQKLIDDQDISISLLSLRILSFHNNTSLLFINKCVILHIIFPE
RDAAIRVLNCFTLPLPAQAVDMIIDTQLCRGILFVLSSLGWIYIFDVVDGTYVAHVDLALHKEDMCNEQQQEPAKISSFTSLKVSQDLDV
AVIVSSSNSAVALNLNLYFRQHPGHLLCERILEDLPIQGPKGVDEDDPVNSAYNMKLAKFSFQIDRSWKAQLSSLNETIKNSKLEVSCCA
PWFQDILHLESPESGNHSTSVQSWAFIPQDIMHGQYNVLQKDHAKTSDPGRSWKIMHISEQEEPIELKCVSVTGFTALFTWEVERMGYTI
TLWDLETQGMQCFSLGTKCIPVDSSGDQQLCFVLTENGLSLILFGLTQEEFLNRLMIHGSASTVDTLCHLNGWGRCSIPIHALEAGIENR
QLDTVNFFLKSKENLFNPSSKSSVSDQFDHLSSHLYLRIYGVELFLKVAGLGPVEYLSSGWNLFDFSVTVFAFLGLLALALNMEPFYFIV
VLRPLQLLRLFKLKERYRNVLDTMFELLPRMASLGLTLLIFYYSFAIVGMEFFCGIVFPNCCNTSTVADAYRWRNHTVGNRTVVEEGYYY
LNNFDNILNSFVTLFELTVVNNWYIIMEGVTSQTSHWSRLYFMTFYIVTMVVMTIIVAFILEAFVFRMNYSRKNQDSEVDGGITLEKEIS
KEELVAVLELYREARGASSDVTRLLETLSQMERYQQHSMVFLGRRSRTKSDLSLKMYQEEIQEWYEEHAREQEQQRQLSSSAAPAAQQPP

--------------------------------------------------------------
>85743_85743_13_SPG11-TPCN1_SPG11_chr15_44925703_ENST00000558319_TPCN1_chr12_113723694_ENST00000335509_length(transcript)=5273nt_BP=1766nt
GAAAGTGACCGGAAGTAACCGCCGGGCCAAGATGGCTGCAGAGGAAGGGGTCGCGAGTGCTGCTTCCGCCGGCGGTAGCTGGGGCACCGC
GGCCATGGGGCGGGTTCTACCGATGCTGTTGGTGCCAGTCCCCGCCGAGGCGATGGGGCAGCTCGGCTCCCGGGCGCAGCTGCGCACACA
GCCGGAGGCTCTGGGGAGCCTGACGGCTGCGGGCAGCCTCCAAGTGCTTTCTTTGACGCCTGGCAGCCGGGGCGGGGGTCGCTGCTGCCT
GGAGGGCCCCTTCTGGCACTTTCTATGGGAGGATTCTCGTAACAGCAGCACACCAACTGAAAAGCCCAAACTGCTCGCTCTTGGTGAAAA
TTATGAACTGCTTATCTATGAATTTAATTTGAAAGATGGAAGATGTGATGCAACCATTTTGTATAGCTGTAGTAGGGAGGCATTGCAAAA
GCTCATTGACGATCAAGATATCAGTATTTCCTTATTGTCTTTGAGAATCCTGTCATTTCACAATAACACATCATTACTGTTCATCAACAA
ATGTGTCATCCTACATATTATATTTCCTGAAAGAGATGCTGCAATTAGAGTACTCAACTGTTTCACACTTCCCTTGCCTGCACAGGCAGT
GGACATGATTATTGACACGCAGCTCTGCAGAGGAATTCTTTTTGTTTTGAGTAGTTTAGGCTGGATCTACATTTTTGATGTTGTGGATGG
TACATATGTAGCTCATGTGGATTTAGCACTTCACAAAGAAGACATGTGTAATGAGCAGCAACAGGAGCCAGCCAAGATTTCTTCATTTAC
TTCACTGAAAGTTTCTCAAGACCTCGATGTTGCAGTGATTGTCAGCTCCTCCAACTCCGCAGTTGCTCTTAACTTAAATTTGTATTTCAG
GCAACACCCAGGACACCTACTGTGTGAAAGAATACTAGAAGATCTTCCTATTCAAGGACCTAAGGGCGTAGATGAAGATGATCCTGTTAA
CTCTGCCTACAACATGAAACTGGCCAAGTTTTCCTTCCAAATTGATAGGTCTTGGAAAGCCCAGCTATCATCATTGAATGAAACAATAAA
GAACTCCAAACTGGAGGTTTCCTGTTGTGCTCCATGGTTCCAGGATATTTTGCATTTGGAGTCACCTGAATCTGGTAACCACAGTACAAG
TGTGCAGAGCTGGGCCTTCATTCCACAGGACATAATGCATGGGCAATATAATGTTCTACAGAAAGATCATGCCAAGACCAGTGATCCAGG
AAGATCATGGAAAATAATGCACATCAGTGAACAAGAGGAACCCATAGAGCTTAAATGTGTGTCTGTGACAGGATTCACTGCACTGTTTAC
TTGGGAAGTGGAAAGGATGGGCTATACCATTACCCTCTGGGATTTGGAGACCCAGGGCATGCAGTGTTTTTCCCTTGGCACAAAGTGTAT
TCCTGTAGACAGTAGTGGAGACCAGCAGCTGTGCTTTGTTTTGACAGAGAATGGACTCTCTCTGATTTTGTTTGGTTTGACTCAAGAAGA
GTTTTTAAACAGACTCATGATCCATGGAAGTGCCAGCACTGTGGACACTCTTTGTCATCTCAATGGCTGGGGAAGGTGCTCAATTCCCAT
ACATGCACTAGAGGCCGGGATAGAAAATCGTCAGCTGGACACAGTAAATTTCTTTTTGAAGAGCAAGGAAAATCTTTTTAATCCATCCTC
AAAATCTTCTGTATCTGATCAGTTTGATCACTTGTCATCCCATTTATATTTAAGAATCTATGGGGTGGAGCTGTTCCTGAAGGTTGCCGG
CCTGGGCCCTGTGGAGTACTTGTCTTCCGGATGGAACTTGTTTGACTTCTCCGTGACAGTGTTCGCCTTCCTGGGACTGCTGGCGCTGGC
CCTCAACATGGAGCCCTTCTATTTCATCGTGGTCCTGCGCCCCCTCCAGCTGCTGAGGTTGTTTAAGTTGAAGGAGCGCTACCGCAACGT
GCTGGACACCATGTTCGAGCTGCTGCCCCGGATGGCCAGCCTGGGCCTCACCCTGCTCATCTTTTACTACTCCTTCGCCATCGTGGGCAT
GGAGTTCTTCTGCGGGATCGTCTTCCCCAACTGCTGCAACACGAGTACAGTGGCAGATGCCTACCGCTGGCGCAACCACACCGTGGGCAA
CAGGACCGTGGTGGAGGAAGGCTACTATTATCTCAATAATTTTGACAACATCCTCAACAGCTTTGTGACCCTGTTTGAGCTCACAGTTGT
CAACAACTGGTACATCATCATGGAAGGCGTCACCTCTCAGACCTCCCACTGGAGCCGCCTCTACTTCATGACCTTTTACATTGTGACCAT
GGTGGTGATGACGATCATTGTCGCCTTTATCCTCGAGGCCTTCGTCTTCCGAATGAACTACAGCCGCAAGAACCAGGACTCGGAAGTTGA
TGGTGGCATCACCCTTGAGAAGGAAATCTCCAAAGAAGAGCTGGTTGCCGTCCTGGAGCTCTACCGGGAGGCACGGGGGGCCTCCTCGGA
TGTCACCAGGCTGCTGGAGACCCTCTCCCAGATGGAGAGATACCAGCAACATTCCATGGTGTTTCTGGGACGGCGATCAAGGACCAAGAG
CGACCTGAGCCTGAAGATGTACCAGGAGGAGATCCAGGAGTGGTATGAGGAGCATGCCAGGGAGCAAGAGCAGCAGCGACAACTCAGCAG
CAGTGCAGCCCCCGCCGCCCAGCAGCCCCCAGGCAGCCGCCAGCGCTCCCAGACCGTTACCTAGCCCAGCGCCCGAAAGCCGTCTCTTCT
ATGCAATAACACAATAGTATTACTCTACTGCGATGTACGGAACTGCGGTGTGTGTACACATACTCACGTATATGCACATATTTATATACA
GGAAGAAAAAAGACAGACAAGATGGGGCTTGGTTTATAACCACCTTGCCCTGTCTTCCTTAACTCCAGAAGCCAGTTTGGTGAGGGGTGG
GGGTGCGGCCACCAGGTCTGAGCTCTTCCTACTGTGGAAGGCTCCAGAAGGCCCTTCACAAGGAGACCCCTCACCTGGATCCAGTCGACT
GCGGGGCTTGCCCCTCATGTGGGCTGGCCTCCATCGGCCACGTCCAAAGCTGTCACTGCTACTGCTTCAGGCTCACATCCCCCCGACCTG
ATGGCGTGCCCGCCCCCTCTCCCTGCGGCCCATGCCACAGGTTTCTGTGTTTTGCTTTAGGGACAGAACCACTTAGGAAGGAAAGAACTC
CCGGTCTCCAGGGTGGTATTTCAGTGTCTGTGATAATGTCACGCAACACCTCTTCGGGGACCAGTGCCCAGGATCTAATGGAAGCGGAAT
TGGGGCAACTGGGCCCATGTGGCCAGAGCTCAGTTAGCCAGTGCCGGGCGGCCACAGATTACACTGACCAATCTCCTCCCTTGGCTCTGC
AAGCCTCCCACCCAGCCTTCTCTGGCTTAACCCTTGTTGGCGAAAACTCTTCCACAGTGGCCTCCTTGGGGACCCAGAACCCGGAGGAAG
GGGCATGAGGCAGGAAGTGGGGCCGATGTCTGCAACCCAGACCACTTCGTGGAATGGGCTCTTGACCAAATCCCTTTTTTTGCGATTTAC
CCGTTCAAGCAAAACAACGTTTTGGTTAACTAAGGATTGTGCTAAAGCCGATACCAGGTCCTTCACACGTGTGCACTAGGAACAGGAGCG
AACAGCACAGAGAGACGCTCCCTGTGGGACGCAGCAGCCCCGTGGCCCCGGCCCAGTTCCCAGCCACCCTCCCTGGCTCTGCTCACACCA
GAGATTTCCATAGCAGGAGCGGTTGGTGCAGAAGTAGGTTCAGATGAACCTCAGTTAACGTCGCCACCCCTCCTCCCACCATGGTACCCT
GTAGGAGCCCTGTATGACATCTGAGCGTGGTGGAGGTAGGAGGGTTGCCAGCTGCAGTGACCCTGCCACAGAGGCAGGGTCAGTGCAGAG
GTCGCTTTGGTTCCGCTTCCCTGGGCCACAGAACGGAACACAGCATAGGTTCTGCAGCAGGAGCCGCAGTGGCAGGATGGAGGGTGCGAA
GGGCAAGGAGTGCACTGCTGGGCATTCCTGGCCAGCCCCGGCCCTCTGGTGCCTGCTTCCTGTGACTTCAGAAGGCAGGTGGACAGAGCC
TCCCTCTGGCCTTGTCCTCTTCCCAGCCACAGAACGGGCAGGGTGGCACCCGACCCCAGGGGAGCAGTACCTGGTCCCCCACCCCCTCCT
CCCAACCACCTCCAAGGCCAAGCTGGGTCCCATAGCCAGCACGGCATGGTTCTCCCCTTCCCCCCTTCCCAGGTCAGGGGAGTTGGACAA
GTAGCAGGTGTTTGTTTTTAAAGCACAGCCCTTTGGGAAAGCAACACATTATTGAGACTCACTGTGATTCCCCCGGGAGTCAGACTGGCT
TTGTCCTCTTCCTCTCTGGAGGGCCATGGGCCATCAGCAGGAGCTCCACATCGAGCCCCAGGCCAGAACCCCCTCCCTTTCACAGAGAGG
GAACTTTATTGCACAATTGGGTGCCTTTTAGCTTTTGTGTGTTGAAATGGGCGTTTTGGAAGCAAGGGTCAGGGGACAGCTTCTAAAGGT
GTGAGTCTCTGACCTGAGCATCTGGGCCTCGCCTGGGCCCTTCTTCCTCCCCAGGGGTGGAAACGTGGAGGGGCCAGCAGCACCCCGGGG
TCTGCCCAGGGGAGTCAAGGCCCCGAGGTGGGGGGGCCTATTCCAGGAGGAGTGGGATCTCGGCCCTGTCCAGAGCGAGTTAATGTGTCC
ATCTGCCCAACCCTGTCCTGAGAAAGGACCTGGTTTTGGCCAGGACCTGACAAATACCCAATGGCAGCAGTGTCAACAGACGGGAGTCCA
GCCAGGGTGGGTGCCCTTGTCATTGAGGTTAGGGACAGCTATCCCCAGGTTATGCCTGGCCCCACCCAGCAGGGAGTTGGGGTCCCCCCA
CAGGCTGTGAGCTCTGTGGGCCCTGGGATGTGATCTAGCTCAGATGCCCTCTCATCCTTGATGTCATAGTTGAGTGCACCCAAGTGGCAC
CCACTGGCGGCCAGGGGCACAGCCTGGTGGTGGTGGCAATAGAACTGTGCCCCTCCTCAGCTCCTCGCTTCCCCTCCCACAGCCCCAGCC
TTACTCCACCATGCGGACAATCATTTTGTACGGATCACGGGAGCAATGCTGTACGGTTTTGTACACTGGTGGTTTGTTTCCTAGAAAACC

>85743_85743_13_SPG11-TPCN1_SPG11_chr15_44925703_ENST00000558319_TPCN1_chr12_113723694_ENST00000335509_length(amino acids)=910AA_BP=579
MAAEEGVASAASAGGSWGTAAMGRVLPMLLVPVPAEAMGQLGSRAQLRTQPEALGSLTAAGSLQVLSLTPGSRGGGRCCLEGPFWHFLWE
DSRNSSTPTEKPKLLALGENYELLIYEFNLKDGRCDATILYSCSREALQKLIDDQDISISLLSLRILSFHNNTSLLFINKCVILHIIFPE
RDAAIRVLNCFTLPLPAQAVDMIIDTQLCRGILFVLSSLGWIYIFDVVDGTYVAHVDLALHKEDMCNEQQQEPAKISSFTSLKVSQDLDV
AVIVSSSNSAVALNLNLYFRQHPGHLLCERILEDLPIQGPKGVDEDDPVNSAYNMKLAKFSFQIDRSWKAQLSSLNETIKNSKLEVSCCA
PWFQDILHLESPESGNHSTSVQSWAFIPQDIMHGQYNVLQKDHAKTSDPGRSWKIMHISEQEEPIELKCVSVTGFTALFTWEVERMGYTI
TLWDLETQGMQCFSLGTKCIPVDSSGDQQLCFVLTENGLSLILFGLTQEEFLNRLMIHGSASTVDTLCHLNGWGRCSIPIHALEAGIENR
QLDTVNFFLKSKENLFNPSSKSSVSDQFDHLSSHLYLRIYGVELFLKVAGLGPVEYLSSGWNLFDFSVTVFAFLGLLALALNMEPFYFIV
VLRPLQLLRLFKLKERYRNVLDTMFELLPRMASLGLTLLIFYYSFAIVGMEFFCGIVFPNCCNTSTVADAYRWRNHTVGNRTVVEEGYYY
LNNFDNILNSFVTLFELTVVNNWYIIMEGVTSQTSHWSRLYFMTFYIVTMVVMTIIVAFILEAFVFRMNYSRKNQDSEVDGGITLEKEIS
KEELVAVLELYREARGASSDVTRLLETLSQMERYQQHSMVFLGRRSRTKSDLSLKMYQEEIQEWYEEHAREQEQQRQLSSSAAPAAQQPP

--------------------------------------------------------------
>85743_85743_14_SPG11-TPCN1_SPG11_chr15_44925703_ENST00000558319_TPCN1_chr12_113723694_ENST00000392569_length(transcript)=2882nt_BP=1766nt
GAAAGTGACCGGAAGTAACCGCCGGGCCAAGATGGCTGCAGAGGAAGGGGTCGCGAGTGCTGCTTCCGCCGGCGGTAGCTGGGGCACCGC
GGCCATGGGGCGGGTTCTACCGATGCTGTTGGTGCCAGTCCCCGCCGAGGCGATGGGGCAGCTCGGCTCCCGGGCGCAGCTGCGCACACA
GCCGGAGGCTCTGGGGAGCCTGACGGCTGCGGGCAGCCTCCAAGTGCTTTCTTTGACGCCTGGCAGCCGGGGCGGGGGTCGCTGCTGCCT
GGAGGGCCCCTTCTGGCACTTTCTATGGGAGGATTCTCGTAACAGCAGCACACCAACTGAAAAGCCCAAACTGCTCGCTCTTGGTGAAAA
TTATGAACTGCTTATCTATGAATTTAATTTGAAAGATGGAAGATGTGATGCAACCATTTTGTATAGCTGTAGTAGGGAGGCATTGCAAAA
GCTCATTGACGATCAAGATATCAGTATTTCCTTATTGTCTTTGAGAATCCTGTCATTTCACAATAACACATCATTACTGTTCATCAACAA
ATGTGTCATCCTACATATTATATTTCCTGAAAGAGATGCTGCAATTAGAGTACTCAACTGTTTCACACTTCCCTTGCCTGCACAGGCAGT
GGACATGATTATTGACACGCAGCTCTGCAGAGGAATTCTTTTTGTTTTGAGTAGTTTAGGCTGGATCTACATTTTTGATGTTGTGGATGG
TACATATGTAGCTCATGTGGATTTAGCACTTCACAAAGAAGACATGTGTAATGAGCAGCAACAGGAGCCAGCCAAGATTTCTTCATTTAC
TTCACTGAAAGTTTCTCAAGACCTCGATGTTGCAGTGATTGTCAGCTCCTCCAACTCCGCAGTTGCTCTTAACTTAAATTTGTATTTCAG
GCAACACCCAGGACACCTACTGTGTGAAAGAATACTAGAAGATCTTCCTATTCAAGGACCTAAGGGCGTAGATGAAGATGATCCTGTTAA
CTCTGCCTACAACATGAAACTGGCCAAGTTTTCCTTCCAAATTGATAGGTCTTGGAAAGCCCAGCTATCATCATTGAATGAAACAATAAA
GAACTCCAAACTGGAGGTTTCCTGTTGTGCTCCATGGTTCCAGGATATTTTGCATTTGGAGTCACCTGAATCTGGTAACCACAGTACAAG
TGTGCAGAGCTGGGCCTTCATTCCACAGGACATAATGCATGGGCAATATAATGTTCTACAGAAAGATCATGCCAAGACCAGTGATCCAGG
AAGATCATGGAAAATAATGCACATCAGTGAACAAGAGGAACCCATAGAGCTTAAATGTGTGTCTGTGACAGGATTCACTGCACTGTTTAC
TTGGGAAGTGGAAAGGATGGGCTATACCATTACCCTCTGGGATTTGGAGACCCAGGGCATGCAGTGTTTTTCCCTTGGCACAAAGTGTAT
TCCTGTAGACAGTAGTGGAGACCAGCAGCTGTGCTTTGTTTTGACAGAGAATGGACTCTCTCTGATTTTGTTTGGTTTGACTCAAGAAGA
GTTTTTAAACAGACTCATGATCCATGGAAGTGCCAGCACTGTGGACACTCTTTGTCATCTCAATGGCTGGGGAAGGTGCTCAATTCCCAT
ACATGCACTAGAGGCCGGGATAGAAAATCGTCAGCTGGACACAGTAAATTTCTTTTTGAAGAGCAAGGAAAATCTTTTTAATCCATCCTC
AAAATCTTCTGTATCTGATCAGTTTGATCACTTGTCATCCCATTTATATTTAAGAATCTATGGGGTGGAGCTGTTCCTGAAGGTTGCCGG
CCTGGGCCCTGTGGAGTACTTGTCTTCCGGATGGAACTTGTTTGACTTCTCCGTGACAGTGTTCGCCTTCCTGGGACTGCTGGCGCTGGC
CCTCAACATGGAGCCCTTCTATTTCATCGTGGTCCTGCGCCCCCTCCAGCTGCTGAGGTTGTTTAAGTTGAAGGAGCGCTACCGCAACGT
GCTGGACACCATGTTCGAGCTGCTGCCCCGGATGGCCAGCCTGGGCCTCACCCTGCTCATCTTTTACTACTCCTTCGCCATCGTGGGCAT
GGAGTTCTTCTGCGGGATCGTCTTCCCCAACTGCTGCAACACGAGTACAGTGGCAGATGCCTACCGCTGGCGCAACCACACCGTGGGCAA
CAGGACCGTGGTGGAGGAAGGCTACTATTATCTCAATAATTTTGACAACATCCTCAACAGCTTTGTGACCCTGTTTGAGCTCACAGTTGT
CAACAACTGGTACATCATCATGGAAGGCGTCACCTCTCAGACCTCCCACTGGAGCCGCCTCTACTTCATGACCTTTTACATTGTGACCAT
GGTGGTGATGACGATCATTGTCGCCTTTATCCTCGAGGCCTTCGTCTTCCGAATGAACTACAGCCGCAAGAACCAGGACTCGGAAGTTGA
TGGTGGCATCACCCTTGAGAAGGAAATCTCCAAAGAAGAGCTGGTTGCCGTCCTGGAGCTCTACCGGGAGGCACGGGGGGCCTCCTCGGA
TGTCACCAGGCTGCTGGAGACCCTCTCCCAGATGGAGAGATACCAGCAACATTCCATGGTGTTTCTGGGACGGCGATCAAGGACCAAGAG
CGACCTGAGCCTGAAGATGTACCAGGAGGAGATCCAGGAGTGGTATGAGGAGCATGCCAGGGAGCAAGAGCAGCAGCGACAACTCAGCAG
CAGTGCAGCCCCCGCCGCCCAGCAGCCCCCAGGCAGCCGCCAGCGCTCCCAGACCGTTACCTAGCCCAGCGCCCGAAAGCCGTCTCTTCT
ATGCAATAACACAATAGTATTACTCTACTGCGATGTACGGAACTGCGGTGTGTGTACACATACTCACGTATATGCACATATTTATATACA

>85743_85743_14_SPG11-TPCN1_SPG11_chr15_44925703_ENST00000558319_TPCN1_chr12_113723694_ENST00000392569_length(amino acids)=910AA_BP=579
MAAEEGVASAASAGGSWGTAAMGRVLPMLLVPVPAEAMGQLGSRAQLRTQPEALGSLTAAGSLQVLSLTPGSRGGGRCCLEGPFWHFLWE
DSRNSSTPTEKPKLLALGENYELLIYEFNLKDGRCDATILYSCSREALQKLIDDQDISISLLSLRILSFHNNTSLLFINKCVILHIIFPE
RDAAIRVLNCFTLPLPAQAVDMIIDTQLCRGILFVLSSLGWIYIFDVVDGTYVAHVDLALHKEDMCNEQQQEPAKISSFTSLKVSQDLDV
AVIVSSSNSAVALNLNLYFRQHPGHLLCERILEDLPIQGPKGVDEDDPVNSAYNMKLAKFSFQIDRSWKAQLSSLNETIKNSKLEVSCCA
PWFQDILHLESPESGNHSTSVQSWAFIPQDIMHGQYNVLQKDHAKTSDPGRSWKIMHISEQEEPIELKCVSVTGFTALFTWEVERMGYTI
TLWDLETQGMQCFSLGTKCIPVDSSGDQQLCFVLTENGLSLILFGLTQEEFLNRLMIHGSASTVDTLCHLNGWGRCSIPIHALEAGIENR
QLDTVNFFLKSKENLFNPSSKSSVSDQFDHLSSHLYLRIYGVELFLKVAGLGPVEYLSSGWNLFDFSVTVFAFLGLLALALNMEPFYFIV
VLRPLQLLRLFKLKERYRNVLDTMFELLPRMASLGLTLLIFYYSFAIVGMEFFCGIVFPNCCNTSTVADAYRWRNHTVGNRTVVEEGYYY
LNNFDNILNSFVTLFELTVVNNWYIIMEGVTSQTSHWSRLYFMTFYIVTMVVMTIIVAFILEAFVFRMNYSRKNQDSEVDGGITLEKEIS
KEELVAVLELYREARGASSDVTRLLETLSQMERYQQHSMVFLGRRSRTKSDLSLKMYQEEIQEWYEEHAREQEQQRQLSSSAAPAAQQPP

--------------------------------------------------------------
>85743_85743_15_SPG11-TPCN1_SPG11_chr15_44925703_ENST00000558319_TPCN1_chr12_113723694_ENST00000541517_length(transcript)=5270nt_BP=1766nt
GAAAGTGACCGGAAGTAACCGCCGGGCCAAGATGGCTGCAGAGGAAGGGGTCGCGAGTGCTGCTTCCGCCGGCGGTAGCTGGGGCACCGC
GGCCATGGGGCGGGTTCTACCGATGCTGTTGGTGCCAGTCCCCGCCGAGGCGATGGGGCAGCTCGGCTCCCGGGCGCAGCTGCGCACACA
GCCGGAGGCTCTGGGGAGCCTGACGGCTGCGGGCAGCCTCCAAGTGCTTTCTTTGACGCCTGGCAGCCGGGGCGGGGGTCGCTGCTGCCT
GGAGGGCCCCTTCTGGCACTTTCTATGGGAGGATTCTCGTAACAGCAGCACACCAACTGAAAAGCCCAAACTGCTCGCTCTTGGTGAAAA
TTATGAACTGCTTATCTATGAATTTAATTTGAAAGATGGAAGATGTGATGCAACCATTTTGTATAGCTGTAGTAGGGAGGCATTGCAAAA
GCTCATTGACGATCAAGATATCAGTATTTCCTTATTGTCTTTGAGAATCCTGTCATTTCACAATAACACATCATTACTGTTCATCAACAA
ATGTGTCATCCTACATATTATATTTCCTGAAAGAGATGCTGCAATTAGAGTACTCAACTGTTTCACACTTCCCTTGCCTGCACAGGCAGT
GGACATGATTATTGACACGCAGCTCTGCAGAGGAATTCTTTTTGTTTTGAGTAGTTTAGGCTGGATCTACATTTTTGATGTTGTGGATGG
TACATATGTAGCTCATGTGGATTTAGCACTTCACAAAGAAGACATGTGTAATGAGCAGCAACAGGAGCCAGCCAAGATTTCTTCATTTAC
TTCACTGAAAGTTTCTCAAGACCTCGATGTTGCAGTGATTGTCAGCTCCTCCAACTCCGCAGTTGCTCTTAACTTAAATTTGTATTTCAG
GCAACACCCAGGACACCTACTGTGTGAAAGAATACTAGAAGATCTTCCTATTCAAGGACCTAAGGGCGTAGATGAAGATGATCCTGTTAA
CTCTGCCTACAACATGAAACTGGCCAAGTTTTCCTTCCAAATTGATAGGTCTTGGAAAGCCCAGCTATCATCATTGAATGAAACAATAAA
GAACTCCAAACTGGAGGTTTCCTGTTGTGCTCCATGGTTCCAGGATATTTTGCATTTGGAGTCACCTGAATCTGGTAACCACAGTACAAG
TGTGCAGAGCTGGGCCTTCATTCCACAGGACATAATGCATGGGCAATATAATGTTCTACAGAAAGATCATGCCAAGACCAGTGATCCAGG
AAGATCATGGAAAATAATGCACATCAGTGAACAAGAGGAACCCATAGAGCTTAAATGTGTGTCTGTGACAGGATTCACTGCACTGTTTAC
TTGGGAAGTGGAAAGGATGGGCTATACCATTACCCTCTGGGATTTGGAGACCCAGGGCATGCAGTGTTTTTCCCTTGGCACAAAGTGTAT
TCCTGTAGACAGTAGTGGAGACCAGCAGCTGTGCTTTGTTTTGACAGAGAATGGACTCTCTCTGATTTTGTTTGGTTTGACTCAAGAAGA
GTTTTTAAACAGACTCATGATCCATGGAAGTGCCAGCACTGTGGACACTCTTTGTCATCTCAATGGCTGGGGAAGGTGCTCAATTCCCAT
ACATGCACTAGAGGCCGGGATAGAAAATCGTCAGCTGGACACAGTAAATTTCTTTTTGAAGAGCAAGGAAAATCTTTTTAATCCATCCTC
AAAATCTTCTGTATCTGATCAGTTTGATCACTTGTCATCCCATTTATATTTAAGAATCTATGGGGTGGAGCTGTTCCTGAAGGTTGCCGG
CCTGGGCCCTGTGGAGTACTTGTCTTCCGGATGGAACTTGTTTGACTTCTCCGTGACAGTGTTCGCCTTCCTGGGACTGCTGGCGCTGGC
CCTCAACATGGAGCCCTTCTATTTCATCGTGGTCCTGCGCCCCCTCCAGCTGCTGAGGTTGTTTAAGTTGAAGGAGCGCTACCGCAACGT
GCTGGACACCATGTTCGAGCTGCTGCCCCGGATGGCCAGCCTGGGCCTCACCCTGCTCATCTTTTACTACTCCTTCGCCATCGTGGGCAT
GGAGTTCTTCTGCGGGATCGTCTTCCCCAACTGCTGCAACACGAGTACAGTGGCAGATGCCTACCGCTGGCGCAACCACACCGTGGGCAA
CAGGACCGTGGTGGAGGAAGGCTACTATTATCTCAATAATTTTGACAACATCCTCAACAGCTTTGTGACCCTGTTTGAGCTCACAGTTGT
CAACAACTGGTACATCATCATGGAAGGCGTCACCTCTCAGACCTCCCACTGGAGCCGCCTCTACTTCATGACCTTTTACATTGTGACCAT
GGTGGTGATGACGATCATTGTCGCCTTTATCCTCGAGGCCTTCGTCTTCCGAATGAACTACAGCCGCAAGAACCAGGACTCGGAAGTTGA
TGGTGGCATCACCCTTGAGAAGGAAATCTCCAAAGAAGAGCTGGTTGCCGTCCTGGAGCTCTACCGGGAGGCACGGGGGGCCTCCTCGGA
TGTCACCAGGCTGCTGGAGACCCTCTCCCAGATGGAGAGATACCAGCAACATTCCATGGTGTTTCTGGGACGGCGATCAAGGACCAAGAG
CGACCTGAGCCTGAAGATGTACCAGGAGGAGATCCAGGAGTGGTATGAGGAGCATGCCAGGGAGCAAGAGCAGCAGCGACAACTCAGCAG
CAGTGCAGCCCCCGCCGCCCAGCAGCCCCCAGGCAGCCGCCAGCGCTCCCAGACCGTTACCTAGCCCAGCGCCCGAAAGCCGTCTCTTCT
ATGCAATAACACAATAGTATTACTCTACTGCGATGTACGGAACTGCGGTGTGTGTACACATACTCACGTATATGCACATATTTATATACA
GGAAGAAAAAAGACAGACAAGATGGGGCTTGGTTTATAACCACCTTGCCCTGTCTTCCTTAACTCCAGAAGCCAGTTTGGTGAGGGGTGG
GGGTGCGGCCACCAGGTCTGAGCTCTTCCTACTGTGGAAGGCTCCAGAAGGCCCTTCACAAGGAGACCCCTCACCTGGATCCAGTCGACT
GCGGGGCTTGCCCCTCATGTGGGCTGGCCTCCATCGGCCACGTCCAAAGCTGTCACTGCTACTGCTTCAGGCTCACATCCCCCCGACCTG
ATGGCGTGCCCGCCCCCTCTCCCTGCGGCCCATGCCACAGGTTTCTGTGTTTTGCTTTAGGGACAGAACCACTTAGGAAGGAAAGAACTC
CCGGTCTCCAGGGTGGTATTTCAGTGTCTGTGATAATGTCACGCAACACCTCTTCGGGGACCAGTGCCCAGGATCTAATGGAAGCGGAAT
TGGGGCAACTGGGCCCATGTGGCCAGAGCTCAGTTAGCCAGTGCCGGGCGGCCACAGATTACACTGACCAATCTCCTCCCTTGGCTCTGC
AAGCCTCCCACCCAGCCTTCTCTGGCTTAACCCTTGTTGGCGAAAACTCTTCCACAGTGGCCTCCTTGGGGACCCAGAACCCGGAGGAAG
GGGCATGAGGCAGGAAGTGGGGCCGATGTCTGCAACCCAGACCACTTCGTGGAATGGGCTCTTGACCAAATCCCTTTTTTTGCGATTTAC
CCGTTCAAGCAAAACAACGTTTTGGTTAACTAAGGATTGTGCTAAAGCCGATACCAGGTCCTTCACACGTGTGCACTAGGAACAGGAGCG
AACAGCACAGAGAGACGCTCCCTGTGGGACGCAGCAGCCCCGTGGCCCCGGCCCAGTTCCCAGCCACCCTCCCTGGCTCTGCTCACACCA
GAGATTTCCATAGCAGGAGCGGTTGGTGCAGAAGTAGGTTCAGATGAACCTCAGTTAACGTCGCCACCCCTCCTCCCACCATGGTACCCT
GTAGGAGCCCTGTATGACATCTGAGCGTGGTGGAGGTAGGAGGGTTGCCAGCTGCAGTGACCCTGCCACAGAGGCAGGGTCAGTGCAGAG
GTCGCTTTGGTTCCGCTTCCCTGGGCCACAGAACGGAACACAGCATAGGTTCTGCAGCAGGAGCCGCAGTGGCAGGATGGAGGGTGCGAA
GGGCAAGGAGTGCACTGCTGGGCATTCCTGGCCAGCCCCGGCCCTCTGGTGCCTGCTTCCTGTGACTTCAGAAGGCAGGTGGACAGAGCC
TCCCTCTGGCCTTGTCCTCTTCCCAGCCACAGAACGGGCAGGGTGGCACCCGACCCCAGGGGAGCAGTACCTGGTCCCCCACCCCCTCCT
CCCAACCACCTCCAAGGCCAAGCTGGGTCCCATAGCCAGCACGGCATGGTTCTCCCCTTCCCCCCTTCCCAGGTCAGGGGAGTTGGACAA
GTAGCAGGTGTTTGTTTTTAAAGCACAGCCCTTTGGGAAAGCAACACATTATTGAGACTCACTGTGATTCCCCCGGGAGTCAGACTGGCT
TTGTCCTCTTCCTCTCTGGAGGGCCATGGGCCATCAGCAGGAGCTCCACATCGAGCCCCAGGCCAGAACCCCCTCCCTTTCACAGAGAGG
GAACTTTATTGCACAATTGGGTGCCTTTTAGCTTTTGTGTGTTGAAATGGGCGTTTTGGAAGCAAGGGTCAGGGGACAGCTTCTAAAGGT
GTGAGTCTCTGACCTGAGCATCTGGGCCTCGCCTGGGCCCTTCTTCCTCCCCAGGGGTGGAAACGTGGAGGGGCCAGCAGCACCCCGGGG
TCTGCCCAGGGGAGTCAAGGCCCCGAGGTGGGGGGGCCTATTCCAGGAGGAGTGGGATCTCGGCCCTGTCCAGAGCGAGTTAATGTGTCC
ATCTGCCCAACCCTGTCCTGAGAAAGGACCTGGTTTTGGCCAGGACCTGACAAATACCCAATGGCAGCAGTGTCAACAGACGGGAGTCCA
GCCAGGGTGGGTGCCCTTGTCATTGAGGTTAGGGACAGCTATCCCCAGGTTATGCCTGGCCCCACCCAGCAGGGAGTTGGGGTCCCCCCA
CAGGCTGTGAGCTCTGTGGGCCCTGGGATGTGATCTAGCTCAGATGCCCTCTCATCCTTGATGTCATAGTTGAGTGCACCCAAGTGGCAC
CCACTGGCGGCCAGGGGCACAGCCTGGTGGTGGTGGCAATAGAACTGTGCCCCTCCTCAGCTCCTCGCTTCCCCTCCCACAGCCCCAGCC
TTACTCCACCATGCGGACAATCATTTTGTACGGATCACGGGAGCAATGCTGTACGGTTTTGTACACTGGTGGTTTGTTTCCTAGAAAACC

>85743_85743_15_SPG11-TPCN1_SPG11_chr15_44925703_ENST00000558319_TPCN1_chr12_113723694_ENST00000541517_length(amino acids)=910AA_BP=579
MAAEEGVASAASAGGSWGTAAMGRVLPMLLVPVPAEAMGQLGSRAQLRTQPEALGSLTAAGSLQVLSLTPGSRGGGRCCLEGPFWHFLWE
DSRNSSTPTEKPKLLALGENYELLIYEFNLKDGRCDATILYSCSREALQKLIDDQDISISLLSLRILSFHNNTSLLFINKCVILHIIFPE
RDAAIRVLNCFTLPLPAQAVDMIIDTQLCRGILFVLSSLGWIYIFDVVDGTYVAHVDLALHKEDMCNEQQQEPAKISSFTSLKVSQDLDV
AVIVSSSNSAVALNLNLYFRQHPGHLLCERILEDLPIQGPKGVDEDDPVNSAYNMKLAKFSFQIDRSWKAQLSSLNETIKNSKLEVSCCA
PWFQDILHLESPESGNHSTSVQSWAFIPQDIMHGQYNVLQKDHAKTSDPGRSWKIMHISEQEEPIELKCVSVTGFTALFTWEVERMGYTI
TLWDLETQGMQCFSLGTKCIPVDSSGDQQLCFVLTENGLSLILFGLTQEEFLNRLMIHGSASTVDTLCHLNGWGRCSIPIHALEAGIENR
QLDTVNFFLKSKENLFNPSSKSSVSDQFDHLSSHLYLRIYGVELFLKVAGLGPVEYLSSGWNLFDFSVTVFAFLGLLALALNMEPFYFIV
VLRPLQLLRLFKLKERYRNVLDTMFELLPRMASLGLTLLIFYYSFAIVGMEFFCGIVFPNCCNTSTVADAYRWRNHTVGNRTVVEEGYYY
LNNFDNILNSFVTLFELTVVNNWYIIMEGVTSQTSHWSRLYFMTFYIVTMVVMTIIVAFILEAFVFRMNYSRKNQDSEVDGGITLEKEIS
KEELVAVLELYREARGASSDVTRLLETLSQMERYQQHSMVFLGRRSRTKSDLSLKMYQEEIQEWYEEHAREQEQQRQLSSSAAPAAQQPP

--------------------------------------------------------------
>85743_85743_16_SPG11-TPCN1_SPG11_chr15_44925703_ENST00000558319_TPCN1_chr12_113723694_ENST00000550785_length(transcript)=5273nt_BP=1766nt
GAAAGTGACCGGAAGTAACCGCCGGGCCAAGATGGCTGCAGAGGAAGGGGTCGCGAGTGCTGCTTCCGCCGGCGGTAGCTGGGGCACCGC
GGCCATGGGGCGGGTTCTACCGATGCTGTTGGTGCCAGTCCCCGCCGAGGCGATGGGGCAGCTCGGCTCCCGGGCGCAGCTGCGCACACA
GCCGGAGGCTCTGGGGAGCCTGACGGCTGCGGGCAGCCTCCAAGTGCTTTCTTTGACGCCTGGCAGCCGGGGCGGGGGTCGCTGCTGCCT
GGAGGGCCCCTTCTGGCACTTTCTATGGGAGGATTCTCGTAACAGCAGCACACCAACTGAAAAGCCCAAACTGCTCGCTCTTGGTGAAAA
TTATGAACTGCTTATCTATGAATTTAATTTGAAAGATGGAAGATGTGATGCAACCATTTTGTATAGCTGTAGTAGGGAGGCATTGCAAAA
GCTCATTGACGATCAAGATATCAGTATTTCCTTATTGTCTTTGAGAATCCTGTCATTTCACAATAACACATCATTACTGTTCATCAACAA
ATGTGTCATCCTACATATTATATTTCCTGAAAGAGATGCTGCAATTAGAGTACTCAACTGTTTCACACTTCCCTTGCCTGCACAGGCAGT
GGACATGATTATTGACACGCAGCTCTGCAGAGGAATTCTTTTTGTTTTGAGTAGTTTAGGCTGGATCTACATTTTTGATGTTGTGGATGG
TACATATGTAGCTCATGTGGATTTAGCACTTCACAAAGAAGACATGTGTAATGAGCAGCAACAGGAGCCAGCCAAGATTTCTTCATTTAC
TTCACTGAAAGTTTCTCAAGACCTCGATGTTGCAGTGATTGTCAGCTCCTCCAACTCCGCAGTTGCTCTTAACTTAAATTTGTATTTCAG
GCAACACCCAGGACACCTACTGTGTGAAAGAATACTAGAAGATCTTCCTATTCAAGGACCTAAGGGCGTAGATGAAGATGATCCTGTTAA
CTCTGCCTACAACATGAAACTGGCCAAGTTTTCCTTCCAAATTGATAGGTCTTGGAAAGCCCAGCTATCATCATTGAATGAAACAATAAA
GAACTCCAAACTGGAGGTTTCCTGTTGTGCTCCATGGTTCCAGGATATTTTGCATTTGGAGTCACCTGAATCTGGTAACCACAGTACAAG
TGTGCAGAGCTGGGCCTTCATTCCACAGGACATAATGCATGGGCAATATAATGTTCTACAGAAAGATCATGCCAAGACCAGTGATCCAGG
AAGATCATGGAAAATAATGCACATCAGTGAACAAGAGGAACCCATAGAGCTTAAATGTGTGTCTGTGACAGGATTCACTGCACTGTTTAC
TTGGGAAGTGGAAAGGATGGGCTATACCATTACCCTCTGGGATTTGGAGACCCAGGGCATGCAGTGTTTTTCCCTTGGCACAAAGTGTAT
TCCTGTAGACAGTAGTGGAGACCAGCAGCTGTGCTTTGTTTTGACAGAGAATGGACTCTCTCTGATTTTGTTTGGTTTGACTCAAGAAGA
GTTTTTAAACAGACTCATGATCCATGGAAGTGCCAGCACTGTGGACACTCTTTGTCATCTCAATGGCTGGGGAAGGTGCTCAATTCCCAT
ACATGCACTAGAGGCCGGGATAGAAAATCGTCAGCTGGACACAGTAAATTTCTTTTTGAAGAGCAAGGAAAATCTTTTTAATCCATCCTC
AAAATCTTCTGTATCTGATCAGTTTGATCACTTGTCATCCCATTTATATTTAAGAATCTATGGGGTGGAGCTGTTCCTGAAGGTTGCCGG
CCTGGGCCCTGTGGAGTACTTGTCTTCCGGATGGAACTTGTTTGACTTCTCCGTGACAGTGTTCGCCTTCCTGGGACTGCTGGCGCTGGC
CCTCAACATGGAGCCCTTCTATTTCATCGTGGTCCTGCGCCCCCTCCAGCTGCTGAGGTTGTTTAAGTTGAAGGAGCGCTACCGCAACGT
GCTGGACACCATGTTCGAGCTGCTGCCCCGGATGGCCAGCCTGGGCCTCACCCTGCTCATCTTTTACTACTCCTTCGCCATCGTGGGCAT
GGAGTTCTTCTGCGGGATCGTCTTCCCCAACTGCTGCAACACGAGTACAGTGGCAGATGCCTACCGCTGGCGCAACCACACCGTGGGCAA
CAGGACCGTGGTGGAGGAAGGCTACTATTATCTCAATAATTTTGACAACATCCTCAACAGCTTTGTGACCCTGTTTGAGCTCACAGTTGT
CAACAACTGGTACATCATCATGGAAGGCGTCACCTCTCAGACCTCCCACTGGAGCCGCCTCTACTTCATGACCTTTTACATTGTGACCAT
GGTGGTGATGACGATCATTGTCGCCTTTATCCTCGAGGCCTTCGTCTTCCGAATGAACTACAGCCGCAAGAACCAGGACTCGGAAGTTGA
TGGTGGCATCACCCTTGAGAAGGAAATCTCCAAAGAAGAGCTGGTTGCCGTCCTGGAGCTCTACCGGGAGGCACGGGGGGCCTCCTCGGA
TGTCACCAGGCTGCTGGAGACCCTCTCCCAGATGGAGAGATACCAGCAACATTCCATGGTGTTTCTGGGACGGCGATCAAGGACCAAGAG
CGACCTGAGCCTGAAGATGTACCAGGAGGAGATCCAGGAGTGGTATGAGGAGCATGCCAGGGAGCAAGAGCAGCAGCGACAACTCAGCAG
CAGTGCAGCCCCCGCCGCCCAGCAGCCCCCAGGCAGCCGCCAGCGCTCCCAGACCGTTACCTAGCCCAGCGCCCGAAAGCCGTCTCTTCT
ATGCAATAACACAATAGTATTACTCTACTGCGATGTACGGAACTGCGGTGTGTGTACACATACTCACGTATATGCACATATTTATATACA
GGAAGAAAAAAGACAGACAAGATGGGGCTTGGTTTATAACCACCTTGCCCTGTCTTCCTTAACTCCAGAAGCCAGTTTGGTGAGGGGTGG
GGGTGCGGCCACCAGGTCTGAGCTCTTCCTACTGTGGAAGGCTCCAGAAGGCCCTTCACAAGGAGACCCCTCACCTGGATCCAGTCGACT
GCGGGGCTTGCCCCTCATGTGGGCTGGCCTCCATCGGCCACGTCCAAAGCTGTCACTGCTACTGCTTCAGGCTCACATCCCCCCGACCTG
ATGGCGTGCCCGCCCCCTCTCCCTGCGGCCCATGCCACAGGTTTCTGTGTTTTGCTTTAGGGACAGAACCACTTAGGAAGGAAAGAACTC
CCGGTCTCCAGGGTGGTATTTCAGTGTCTGTGATAATGTCACGCAACACCTCTTCGGGGACCAGTGCCCAGGATCTAATGGAAGCGGAAT
TGGGGCAACTGGGCCCATGTGGCCAGAGCTCAGTTAGCCAGTGCCGGGCGGCCACAGATTACACTGACCAATCTCCTCCCTTGGCTCTGC
AAGCCTCCCACCCAGCCTTCTCTGGCTTAACCCTTGTTGGCGAAAACTCTTCCACAGTGGCCTCCTTGGGGACCCAGAACCCGGAGGAAG
GGGCATGAGGCAGGAAGTGGGGCCGATGTCTGCAACCCAGACCACTTCGTGGAATGGGCTCTTGACCAAATCCCTTTTTTTGCGATTTAC
CCGTTCAAGCAAAACAACGTTTTGGTTAACTAAGGATTGTGCTAAAGCCGATACCAGGTCCTTCACACGTGTGCACTAGGAACAGGAGCG
AACAGCACAGAGAGACGCTCCCTGTGGGACGCAGCAGCCCCGTGGCCCCGGCCCAGTTCCCAGCCACCCTCCCTGGCTCTGCTCACACCA
GAGATTTCCATAGCAGGAGCGGTTGGTGCAGAAGTAGGTTCAGATGAACCTCAGTTAACGTCGCCACCCCTCCTCCCACCATGGTACCCT
GTAGGAGCCCTGTATGACATCTGAGCGTGGTGGAGGTAGGAGGGTTGCCAGCTGCAGTGACCCTGCCACAGAGGCAGGGTCAGTGCAGAG
GTCGCTTTGGTTCCGCTTCCCTGGGCCACAGAACGGAACACAGCATAGGTTCTGCAGCAGGAGCCGCAGTGGCAGGATGGAGGGTGCGAA
GGGCAAGGAGTGCACTGCTGGGCATTCCTGGCCAGCCCCGGCCCTCTGGTGCCTGCTTCCTGTGACTTCAGAAGGCAGGTGGACAGAGCC
TCCCTCTGGCCTTGTCCTCTTCCCAGCCACAGAACGGGCAGGGTGGCACCCGACCCCAGGGGAGCAGTACCTGGTCCCCCACCCCCTCCT
CCCAACCACCTCCAAGGCCAAGCTGGGTCCCATAGCCAGCACGGCATGGTTCTCCCCTTCCCCCCTTCCCAGGTCAGGGGAGTTGGACAA
GTAGCAGGTGTTTGTTTTTAAAGCACAGCCCTTTGGGAAAGCAACACATTATTGAGACTCACTGTGATTCCCCCGGGAGTCAGACTGGCT
TTGTCCTCTTCCTCTCTGGAGGGCCATGGGCCATCAGCAGGAGCTCCACATCGAGCCCCAGGCCAGAACCCCCTCCCTTTCACAGAGAGG
GAACTTTATTGCACAATTGGGTGCCTTTTAGCTTTTGTGTGTTGAAATGGGCGTTTTGGAAGCAAGGGTCAGGGGACAGCTTCTAAAGGT
GTGAGTCTCTGACCTGAGCATCTGGGCCTCGCCTGGGCCCTTCTTCCTCCCCAGGGGTGGAAACGTGGAGGGGCCAGCAGCACCCCGGGG
TCTGCCCAGGGGAGTCAAGGCCCCGAGGTGGGGGGGCCTATTCCAGGAGGAGTGGGATCTCGGCCCTGTCCAGAGCGAGTTAATGTGTCC
ATCTGCCCAACCCTGTCCTGAGAAAGGACCTGGTTTTGGCCAGGACCTGACAAATACCCAATGGCAGCAGTGTCAACAGACGGGAGTCCA
GCCAGGGTGGGTGCCCTTGTCATTGAGGTTAGGGACAGCTATCCCCAGGTTATGCCTGGCCCCACCCAGCAGGGAGTTGGGGTCCCCCCA
CAGGCTGTGAGCTCTGTGGGCCCTGGGATGTGATCTAGCTCAGATGCCCTCTCATCCTTGATGTCATAGTTGAGTGCACCCAAGTGGCAC
CCACTGGCGGCCAGGGGCACAGCCTGGTGGTGGTGGCAATAGAACTGTGCCCCTCCTCAGCTCCTCGCTTCCCCTCCCACAGCCCCAGCC
TTACTCCACCATGCGGACAATCATTTTGTACGGATCACGGGAGCAATGCTGTACGGTTTTGTACACTGGTGGTTTGTTTCCTAGAAAACC

>85743_85743_16_SPG11-TPCN1_SPG11_chr15_44925703_ENST00000558319_TPCN1_chr12_113723694_ENST00000550785_length(amino acids)=910AA_BP=579
MAAEEGVASAASAGGSWGTAAMGRVLPMLLVPVPAEAMGQLGSRAQLRTQPEALGSLTAAGSLQVLSLTPGSRGGGRCCLEGPFWHFLWE
DSRNSSTPTEKPKLLALGENYELLIYEFNLKDGRCDATILYSCSREALQKLIDDQDISISLLSLRILSFHNNTSLLFINKCVILHIIFPE
RDAAIRVLNCFTLPLPAQAVDMIIDTQLCRGILFVLSSLGWIYIFDVVDGTYVAHVDLALHKEDMCNEQQQEPAKISSFTSLKVSQDLDV
AVIVSSSNSAVALNLNLYFRQHPGHLLCERILEDLPIQGPKGVDEDDPVNSAYNMKLAKFSFQIDRSWKAQLSSLNETIKNSKLEVSCCA
PWFQDILHLESPESGNHSTSVQSWAFIPQDIMHGQYNVLQKDHAKTSDPGRSWKIMHISEQEEPIELKCVSVTGFTALFTWEVERMGYTI
TLWDLETQGMQCFSLGTKCIPVDSSGDQQLCFVLTENGLSLILFGLTQEEFLNRLMIHGSASTVDTLCHLNGWGRCSIPIHALEAGIENR
QLDTVNFFLKSKENLFNPSSKSSVSDQFDHLSSHLYLRIYGVELFLKVAGLGPVEYLSSGWNLFDFSVTVFAFLGLLALALNMEPFYFIV
VLRPLQLLRLFKLKERYRNVLDTMFELLPRMASLGLTLLIFYYSFAIVGMEFFCGIVFPNCCNTSTVADAYRWRNHTVGNRTVVEEGYYY
LNNFDNILNSFVTLFELTVVNNWYIIMEGVTSQTSHWSRLYFMTFYIVTMVVMTIIVAFILEAFVFRMNYSRKNQDSEVDGGITLEKEIS
KEELVAVLELYREARGASSDVTRLLETLSQMERYQQHSMVFLGRRSRTKSDLSLKMYQEEIQEWYEEHAREQEQQRQLSSSAAPAAQQPP

--------------------------------------------------------------
>85743_85743_17_SPG11-TPCN1_SPG11_chr15_44925703_ENST00000559193_TPCN1_chr12_113723694_ENST00000335509_length(transcript)=5253nt_BP=1746nt
GCCGGGCCAAGATGGCTGCAGAGGAAGGGGTCGCGAGTGCTGCTTCCGCCGGCGGTAGCTGGGGCACCGCGGCCATGGGGCGGGTTCTAC
CGATGCTGTTGGTGCCAGTCCCCGCCGAGGCGATGGGGCAGCTCGGCTCCCGGGCGCAGCTGCGCACACAGCCGGAGGCTCTGGGGAGCC
TGACGGCTGCGGGCAGCCTCCAAGTGCTTTCTTTGACGCCTGGCAGCCGGGGCGGGGGTCGCTGCTGCCTGGAGGGCCCCTTCTGGCACT
TTCTATGGGAGGATTCTCGTAACAGCAGCACACCAACTGAAAAGCCCAAACTGCTCGCTCTTGGTGAAAATTATGAACTGCTTATCTATG
AATTTAATTTGAAAGATGGAAGATGTGATGCAACCATTTTGTATAGCTGTAGTAGGGAGGCATTGCAAAAGCTCATTGACGATCAAGATA
TCAGTATTTCCTTATTGTCTTTGAGAATCCTGTCATTTCACAATAACACATCATTACTGTTCATCAACAAATGTGTCATCCTACATATTA
TATTTCCTGAAAGAGATGCTGCAATTAGAGTACTCAACTGTTTCACACTTCCCTTGCCTGCACAGGCAGTGGACATGATTATTGACACGC
AGCTCTGCAGAGGAATTCTTTTTGTTTTGAGTAGTTTAGGCTGGATCTACATTTTTGATGTTGTGGATGGTACATATGTAGCTCATGTGG
ATTTAGCACTTCACAAAGAAGACATGTGTAATGAGCAGCAACAGGAGCCAGCCAAGATTTCTTCATTTACTTCACTGAAAGTTTCTCAAG
ACCTCGATGTTGCAGTGATTGTCAGCTCCTCCAACTCCGCAGTTGCTCTTAACTTAAATTTGTATTTCAGGCAACACCCAGGACACCTAC
TGTGTGAAAGAATACTAGAAGATCTTCCTATTCAAGGACCTAAGGGCGTAGATGAAGATGATCCTGTTAACTCTGCCTACAACATGAAAC
TGGCCAAGTTTTCCTTCCAAATTGATAGGTCTTGGAAAGCCCAGCTATCATCATTGAATGAAACAATAAAGAACTCCAAACTGGAGGTTT
CCTGTTGTGCTCCATGGTTCCAGGATATTTTGCATTTGGAGTCACCTGAATCTGGTAACCACAGTACAAGTGTGCAGAGCTGGGCCTTCA
TTCCACAGGACATAATGCATGGGCAATATAATGTTCTACAGAAAGATCATGCCAAGACCAGTGATCCAGGAAGATCATGGAAAATAATGC
ACATCAGTGAACAAGAGGAACCCATAGAGCTTAAATGTGTGTCTGTGACAGGATTCACTGCACTGTTTACTTGGGAAGTGGAAAGGATGG
GCTATACCATTACCCTCTGGGATTTGGAGACCCAGGGCATGCAGTGTTTTTCCCTTGGCACAAAGTGTATTCCTGTAGACAGTAGTGGAG
ACCAGCAGCTGTGCTTTGTTTTGACAGAGAATGGACTCTCTCTGATTTTGTTTGGTTTGACTCAAGAAGAGTTTTTAAACAGACTCATGA
TCCATGGAAGTGCCAGCACTGTGGACACTCTTTGTCATCTCAATGGCTGGGGAAGGTGCTCAATTCCCATACATGCACTAGAGGCCGGGA
TAGAAAATCGTCAGCTGGACACAGTAAATTTCTTTTTGAAGAGCAAGGAAAATCTTTTTAATCCATCCTCAAAATCTTCTGTATCTGATC
AGTTTGATCACTTGTCATCCCATTTATATTTAAGAATCTATGGGGTGGAGCTGTTCCTGAAGGTTGCCGGCCTGGGCCCTGTGGAGTACT
TGTCTTCCGGATGGAACTTGTTTGACTTCTCCGTGACAGTGTTCGCCTTCCTGGGACTGCTGGCGCTGGCCCTCAACATGGAGCCCTTCT
ATTTCATCGTGGTCCTGCGCCCCCTCCAGCTGCTGAGGTTGTTTAAGTTGAAGGAGCGCTACCGCAACGTGCTGGACACCATGTTCGAGC
TGCTGCCCCGGATGGCCAGCCTGGGCCTCACCCTGCTCATCTTTTACTACTCCTTCGCCATCGTGGGCATGGAGTTCTTCTGCGGGATCG
TCTTCCCCAACTGCTGCAACACGAGTACAGTGGCAGATGCCTACCGCTGGCGCAACCACACCGTGGGCAACAGGACCGTGGTGGAGGAAG
GCTACTATTATCTCAATAATTTTGACAACATCCTCAACAGCTTTGTGACCCTGTTTGAGCTCACAGTTGTCAACAACTGGTACATCATCA
TGGAAGGCGTCACCTCTCAGACCTCCCACTGGAGCCGCCTCTACTTCATGACCTTTTACATTGTGACCATGGTGGTGATGACGATCATTG
TCGCCTTTATCCTCGAGGCCTTCGTCTTCCGAATGAACTACAGCCGCAAGAACCAGGACTCGGAAGTTGATGGTGGCATCACCCTTGAGA
AGGAAATCTCCAAAGAAGAGCTGGTTGCCGTCCTGGAGCTCTACCGGGAGGCACGGGGGGCCTCCTCGGATGTCACCAGGCTGCTGGAGA
CCCTCTCCCAGATGGAGAGATACCAGCAACATTCCATGGTGTTTCTGGGACGGCGATCAAGGACCAAGAGCGACCTGAGCCTGAAGATGT
ACCAGGAGGAGATCCAGGAGTGGTATGAGGAGCATGCCAGGGAGCAAGAGCAGCAGCGACAACTCAGCAGCAGTGCAGCCCCCGCCGCCC
AGCAGCCCCCAGGCAGCCGCCAGCGCTCCCAGACCGTTACCTAGCCCAGCGCCCGAAAGCCGTCTCTTCTATGCAATAACACAATAGTAT
TACTCTACTGCGATGTACGGAACTGCGGTGTGTGTACACATACTCACGTATATGCACATATTTATATACAGGAAGAAAAAAGACAGACAA
GATGGGGCTTGGTTTATAACCACCTTGCCCTGTCTTCCTTAACTCCAGAAGCCAGTTTGGTGAGGGGTGGGGGTGCGGCCACCAGGTCTG
AGCTCTTCCTACTGTGGAAGGCTCCAGAAGGCCCTTCACAAGGAGACCCCTCACCTGGATCCAGTCGACTGCGGGGCTTGCCCCTCATGT
GGGCTGGCCTCCATCGGCCACGTCCAAAGCTGTCACTGCTACTGCTTCAGGCTCACATCCCCCCGACCTGATGGCGTGCCCGCCCCCTCT
CCCTGCGGCCCATGCCACAGGTTTCTGTGTTTTGCTTTAGGGACAGAACCACTTAGGAAGGAAAGAACTCCCGGTCTCCAGGGTGGTATT
TCAGTGTCTGTGATAATGTCACGCAACACCTCTTCGGGGACCAGTGCCCAGGATCTAATGGAAGCGGAATTGGGGCAACTGGGCCCATGT
GGCCAGAGCTCAGTTAGCCAGTGCCGGGCGGCCACAGATTACACTGACCAATCTCCTCCCTTGGCTCTGCAAGCCTCCCACCCAGCCTTC
TCTGGCTTAACCCTTGTTGGCGAAAACTCTTCCACAGTGGCCTCCTTGGGGACCCAGAACCCGGAGGAAGGGGCATGAGGCAGGAAGTGG
GGCCGATGTCTGCAACCCAGACCACTTCGTGGAATGGGCTCTTGACCAAATCCCTTTTTTTGCGATTTACCCGTTCAAGCAAAACAACGT
TTTGGTTAACTAAGGATTGTGCTAAAGCCGATACCAGGTCCTTCACACGTGTGCACTAGGAACAGGAGCGAACAGCACAGAGAGACGCTC
CCTGTGGGACGCAGCAGCCCCGTGGCCCCGGCCCAGTTCCCAGCCACCCTCCCTGGCTCTGCTCACACCAGAGATTTCCATAGCAGGAGC
GGTTGGTGCAGAAGTAGGTTCAGATGAACCTCAGTTAACGTCGCCACCCCTCCTCCCACCATGGTACCCTGTAGGAGCCCTGTATGACAT
CTGAGCGTGGTGGAGGTAGGAGGGTTGCCAGCTGCAGTGACCCTGCCACAGAGGCAGGGTCAGTGCAGAGGTCGCTTTGGTTCCGCTTCC
CTGGGCCACAGAACGGAACACAGCATAGGTTCTGCAGCAGGAGCCGCAGTGGCAGGATGGAGGGTGCGAAGGGCAAGGAGTGCACTGCTG
GGCATTCCTGGCCAGCCCCGGCCCTCTGGTGCCTGCTTCCTGTGACTTCAGAAGGCAGGTGGACAGAGCCTCCCTCTGGCCTTGTCCTCT
TCCCAGCCACAGAACGGGCAGGGTGGCACCCGACCCCAGGGGAGCAGTACCTGGTCCCCCACCCCCTCCTCCCAACCACCTCCAAGGCCA
AGCTGGGTCCCATAGCCAGCACGGCATGGTTCTCCCCTTCCCCCCTTCCCAGGTCAGGGGAGTTGGACAAGTAGCAGGTGTTTGTTTTTA
AAGCACAGCCCTTTGGGAAAGCAACACATTATTGAGACTCACTGTGATTCCCCCGGGAGTCAGACTGGCTTTGTCCTCTTCCTCTCTGGA
GGGCCATGGGCCATCAGCAGGAGCTCCACATCGAGCCCCAGGCCAGAACCCCCTCCCTTTCACAGAGAGGGAACTTTATTGCACAATTGG
GTGCCTTTTAGCTTTTGTGTGTTGAAATGGGCGTTTTGGAAGCAAGGGTCAGGGGACAGCTTCTAAAGGTGTGAGTCTCTGACCTGAGCA
TCTGGGCCTCGCCTGGGCCCTTCTTCCTCCCCAGGGGTGGAAACGTGGAGGGGCCAGCAGCACCCCGGGGTCTGCCCAGGGGAGTCAAGG
CCCCGAGGTGGGGGGGCCTATTCCAGGAGGAGTGGGATCTCGGCCCTGTCCAGAGCGAGTTAATGTGTCCATCTGCCCAACCCTGTCCTG
AGAAAGGACCTGGTTTTGGCCAGGACCTGACAAATACCCAATGGCAGCAGTGTCAACAGACGGGAGTCCAGCCAGGGTGGGTGCCCTTGT
CATTGAGGTTAGGGACAGCTATCCCCAGGTTATGCCTGGCCCCACCCAGCAGGGAGTTGGGGTCCCCCCACAGGCTGTGAGCTCTGTGGG
CCCTGGGATGTGATCTAGCTCAGATGCCCTCTCATCCTTGATGTCATAGTTGAGTGCACCCAAGTGGCACCCACTGGCGGCCAGGGGCAC
AGCCTGGTGGTGGTGGCAATAGAACTGTGCCCCTCCTCAGCTCCTCGCTTCCCCTCCCACAGCCCCAGCCTTACTCCACCATGCGGACAA
TCATTTTGTACGGATCACGGGAGCAATGCTGTACGGTTTTGTACACTGGTGGTTTGTTTCCTAGAAAACCCATTGTGTCTCTGGATTTCT

>85743_85743_17_SPG11-TPCN1_SPG11_chr15_44925703_ENST00000559193_TPCN1_chr12_113723694_ENST00000335509_length(amino acids)=910AA_BP=579
MAAEEGVASAASAGGSWGTAAMGRVLPMLLVPVPAEAMGQLGSRAQLRTQPEALGSLTAAGSLQVLSLTPGSRGGGRCCLEGPFWHFLWE
DSRNSSTPTEKPKLLALGENYELLIYEFNLKDGRCDATILYSCSREALQKLIDDQDISISLLSLRILSFHNNTSLLFINKCVILHIIFPE
RDAAIRVLNCFTLPLPAQAVDMIIDTQLCRGILFVLSSLGWIYIFDVVDGTYVAHVDLALHKEDMCNEQQQEPAKISSFTSLKVSQDLDV
AVIVSSSNSAVALNLNLYFRQHPGHLLCERILEDLPIQGPKGVDEDDPVNSAYNMKLAKFSFQIDRSWKAQLSSLNETIKNSKLEVSCCA
PWFQDILHLESPESGNHSTSVQSWAFIPQDIMHGQYNVLQKDHAKTSDPGRSWKIMHISEQEEPIELKCVSVTGFTALFTWEVERMGYTI
TLWDLETQGMQCFSLGTKCIPVDSSGDQQLCFVLTENGLSLILFGLTQEEFLNRLMIHGSASTVDTLCHLNGWGRCSIPIHALEAGIENR
QLDTVNFFLKSKENLFNPSSKSSVSDQFDHLSSHLYLRIYGVELFLKVAGLGPVEYLSSGWNLFDFSVTVFAFLGLLALALNMEPFYFIV
VLRPLQLLRLFKLKERYRNVLDTMFELLPRMASLGLTLLIFYYSFAIVGMEFFCGIVFPNCCNTSTVADAYRWRNHTVGNRTVVEEGYYY
LNNFDNILNSFVTLFELTVVNNWYIIMEGVTSQTSHWSRLYFMTFYIVTMVVMTIIVAFILEAFVFRMNYSRKNQDSEVDGGITLEKEIS
KEELVAVLELYREARGASSDVTRLLETLSQMERYQQHSMVFLGRRSRTKSDLSLKMYQEEIQEWYEEHAREQEQQRQLSSSAAPAAQQPP

--------------------------------------------------------------
>85743_85743_18_SPG11-TPCN1_SPG11_chr15_44925703_ENST00000559193_TPCN1_chr12_113723694_ENST00000392569_length(transcript)=2862nt_BP=1746nt
GCCGGGCCAAGATGGCTGCAGAGGAAGGGGTCGCGAGTGCTGCTTCCGCCGGCGGTAGCTGGGGCACCGCGGCCATGGGGCGGGTTCTAC
CGATGCTGTTGGTGCCAGTCCCCGCCGAGGCGATGGGGCAGCTCGGCTCCCGGGCGCAGCTGCGCACACAGCCGGAGGCTCTGGGGAGCC
TGACGGCTGCGGGCAGCCTCCAAGTGCTTTCTTTGACGCCTGGCAGCCGGGGCGGGGGTCGCTGCTGCCTGGAGGGCCCCTTCTGGCACT
TTCTATGGGAGGATTCTCGTAACAGCAGCACACCAACTGAAAAGCCCAAACTGCTCGCTCTTGGTGAAAATTATGAACTGCTTATCTATG
AATTTAATTTGAAAGATGGAAGATGTGATGCAACCATTTTGTATAGCTGTAGTAGGGAGGCATTGCAAAAGCTCATTGACGATCAAGATA
TCAGTATTTCCTTATTGTCTTTGAGAATCCTGTCATTTCACAATAACACATCATTACTGTTCATCAACAAATGTGTCATCCTACATATTA
TATTTCCTGAAAGAGATGCTGCAATTAGAGTACTCAACTGTTTCACACTTCCCTTGCCTGCACAGGCAGTGGACATGATTATTGACACGC
AGCTCTGCAGAGGAATTCTTTTTGTTTTGAGTAGTTTAGGCTGGATCTACATTTTTGATGTTGTGGATGGTACATATGTAGCTCATGTGG
ATTTAGCACTTCACAAAGAAGACATGTGTAATGAGCAGCAACAGGAGCCAGCCAAGATTTCTTCATTTACTTCACTGAAAGTTTCTCAAG
ACCTCGATGTTGCAGTGATTGTCAGCTCCTCCAACTCCGCAGTTGCTCTTAACTTAAATTTGTATTTCAGGCAACACCCAGGACACCTAC
TGTGTGAAAGAATACTAGAAGATCTTCCTATTCAAGGACCTAAGGGCGTAGATGAAGATGATCCTGTTAACTCTGCCTACAACATGAAAC
TGGCCAAGTTTTCCTTCCAAATTGATAGGTCTTGGAAAGCCCAGCTATCATCATTGAATGAAACAATAAAGAACTCCAAACTGGAGGTTT
CCTGTTGTGCTCCATGGTTCCAGGATATTTTGCATTTGGAGTCACCTGAATCTGGTAACCACAGTACAAGTGTGCAGAGCTGGGCCTTCA
TTCCACAGGACATAATGCATGGGCAATATAATGTTCTACAGAAAGATCATGCCAAGACCAGTGATCCAGGAAGATCATGGAAAATAATGC
ACATCAGTGAACAAGAGGAACCCATAGAGCTTAAATGTGTGTCTGTGACAGGATTCACTGCACTGTTTACTTGGGAAGTGGAAAGGATGG
GCTATACCATTACCCTCTGGGATTTGGAGACCCAGGGCATGCAGTGTTTTTCCCTTGGCACAAAGTGTATTCCTGTAGACAGTAGTGGAG
ACCAGCAGCTGTGCTTTGTTTTGACAGAGAATGGACTCTCTCTGATTTTGTTTGGTTTGACTCAAGAAGAGTTTTTAAACAGACTCATGA
TCCATGGAAGTGCCAGCACTGTGGACACTCTTTGTCATCTCAATGGCTGGGGAAGGTGCTCAATTCCCATACATGCACTAGAGGCCGGGA
TAGAAAATCGTCAGCTGGACACAGTAAATTTCTTTTTGAAGAGCAAGGAAAATCTTTTTAATCCATCCTCAAAATCTTCTGTATCTGATC
AGTTTGATCACTTGTCATCCCATTTATATTTAAGAATCTATGGGGTGGAGCTGTTCCTGAAGGTTGCCGGCCTGGGCCCTGTGGAGTACT
TGTCTTCCGGATGGAACTTGTTTGACTTCTCCGTGACAGTGTTCGCCTTCCTGGGACTGCTGGCGCTGGCCCTCAACATGGAGCCCTTCT
ATTTCATCGTGGTCCTGCGCCCCCTCCAGCTGCTGAGGTTGTTTAAGTTGAAGGAGCGCTACCGCAACGTGCTGGACACCATGTTCGAGC
TGCTGCCCCGGATGGCCAGCCTGGGCCTCACCCTGCTCATCTTTTACTACTCCTTCGCCATCGTGGGCATGGAGTTCTTCTGCGGGATCG
TCTTCCCCAACTGCTGCAACACGAGTACAGTGGCAGATGCCTACCGCTGGCGCAACCACACCGTGGGCAACAGGACCGTGGTGGAGGAAG
GCTACTATTATCTCAATAATTTTGACAACATCCTCAACAGCTTTGTGACCCTGTTTGAGCTCACAGTTGTCAACAACTGGTACATCATCA
TGGAAGGCGTCACCTCTCAGACCTCCCACTGGAGCCGCCTCTACTTCATGACCTTTTACATTGTGACCATGGTGGTGATGACGATCATTG
TCGCCTTTATCCTCGAGGCCTTCGTCTTCCGAATGAACTACAGCCGCAAGAACCAGGACTCGGAAGTTGATGGTGGCATCACCCTTGAGA
AGGAAATCTCCAAAGAAGAGCTGGTTGCCGTCCTGGAGCTCTACCGGGAGGCACGGGGGGCCTCCTCGGATGTCACCAGGCTGCTGGAGA
CCCTCTCCCAGATGGAGAGATACCAGCAACATTCCATGGTGTTTCTGGGACGGCGATCAAGGACCAAGAGCGACCTGAGCCTGAAGATGT
ACCAGGAGGAGATCCAGGAGTGGTATGAGGAGCATGCCAGGGAGCAAGAGCAGCAGCGACAACTCAGCAGCAGTGCAGCCCCCGCCGCCC
AGCAGCCCCCAGGCAGCCGCCAGCGCTCCCAGACCGTTACCTAGCCCAGCGCCCGAAAGCCGTCTCTTCTATGCAATAACACAATAGTAT

>85743_85743_18_SPG11-TPCN1_SPG11_chr15_44925703_ENST00000559193_TPCN1_chr12_113723694_ENST00000392569_length(amino acids)=910AA_BP=579
MAAEEGVASAASAGGSWGTAAMGRVLPMLLVPVPAEAMGQLGSRAQLRTQPEALGSLTAAGSLQVLSLTPGSRGGGRCCLEGPFWHFLWE
DSRNSSTPTEKPKLLALGENYELLIYEFNLKDGRCDATILYSCSREALQKLIDDQDISISLLSLRILSFHNNTSLLFINKCVILHIIFPE
RDAAIRVLNCFTLPLPAQAVDMIIDTQLCRGILFVLSSLGWIYIFDVVDGTYVAHVDLALHKEDMCNEQQQEPAKISSFTSLKVSQDLDV
AVIVSSSNSAVALNLNLYFRQHPGHLLCERILEDLPIQGPKGVDEDDPVNSAYNMKLAKFSFQIDRSWKAQLSSLNETIKNSKLEVSCCA
PWFQDILHLESPESGNHSTSVQSWAFIPQDIMHGQYNVLQKDHAKTSDPGRSWKIMHISEQEEPIELKCVSVTGFTALFTWEVERMGYTI
TLWDLETQGMQCFSLGTKCIPVDSSGDQQLCFVLTENGLSLILFGLTQEEFLNRLMIHGSASTVDTLCHLNGWGRCSIPIHALEAGIENR
QLDTVNFFLKSKENLFNPSSKSSVSDQFDHLSSHLYLRIYGVELFLKVAGLGPVEYLSSGWNLFDFSVTVFAFLGLLALALNMEPFYFIV
VLRPLQLLRLFKLKERYRNVLDTMFELLPRMASLGLTLLIFYYSFAIVGMEFFCGIVFPNCCNTSTVADAYRWRNHTVGNRTVVEEGYYY
LNNFDNILNSFVTLFELTVVNNWYIIMEGVTSQTSHWSRLYFMTFYIVTMVVMTIIVAFILEAFVFRMNYSRKNQDSEVDGGITLEKEIS
KEELVAVLELYREARGASSDVTRLLETLSQMERYQQHSMVFLGRRSRTKSDLSLKMYQEEIQEWYEEHAREQEQQRQLSSSAAPAAQQPP

--------------------------------------------------------------
>85743_85743_19_SPG11-TPCN1_SPG11_chr15_44925703_ENST00000559193_TPCN1_chr12_113723694_ENST00000541517_length(transcript)=5250nt_BP=1746nt
GCCGGGCCAAGATGGCTGCAGAGGAAGGGGTCGCGAGTGCTGCTTCCGCCGGCGGTAGCTGGGGCACCGCGGCCATGGGGCGGGTTCTAC
CGATGCTGTTGGTGCCAGTCCCCGCCGAGGCGATGGGGCAGCTCGGCTCCCGGGCGCAGCTGCGCACACAGCCGGAGGCTCTGGGGAGCC
TGACGGCTGCGGGCAGCCTCCAAGTGCTTTCTTTGACGCCTGGCAGCCGGGGCGGGGGTCGCTGCTGCCTGGAGGGCCCCTTCTGGCACT
TTCTATGGGAGGATTCTCGTAACAGCAGCACACCAACTGAAAAGCCCAAACTGCTCGCTCTTGGTGAAAATTATGAACTGCTTATCTATG
AATTTAATTTGAAAGATGGAAGATGTGATGCAACCATTTTGTATAGCTGTAGTAGGGAGGCATTGCAAAAGCTCATTGACGATCAAGATA
TCAGTATTTCCTTATTGTCTTTGAGAATCCTGTCATTTCACAATAACACATCATTACTGTTCATCAACAAATGTGTCATCCTACATATTA
TATTTCCTGAAAGAGATGCTGCAATTAGAGTACTCAACTGTTTCACACTTCCCTTGCCTGCACAGGCAGTGGACATGATTATTGACACGC
AGCTCTGCAGAGGAATTCTTTTTGTTTTGAGTAGTTTAGGCTGGATCTACATTTTTGATGTTGTGGATGGTACATATGTAGCTCATGTGG
ATTTAGCACTTCACAAAGAAGACATGTGTAATGAGCAGCAACAGGAGCCAGCCAAGATTTCTTCATTTACTTCACTGAAAGTTTCTCAAG
ACCTCGATGTTGCAGTGATTGTCAGCTCCTCCAACTCCGCAGTTGCTCTTAACTTAAATTTGTATTTCAGGCAACACCCAGGACACCTAC
TGTGTGAAAGAATACTAGAAGATCTTCCTATTCAAGGACCTAAGGGCGTAGATGAAGATGATCCTGTTAACTCTGCCTACAACATGAAAC
TGGCCAAGTTTTCCTTCCAAATTGATAGGTCTTGGAAAGCCCAGCTATCATCATTGAATGAAACAATAAAGAACTCCAAACTGGAGGTTT
CCTGTTGTGCTCCATGGTTCCAGGATATTTTGCATTTGGAGTCACCTGAATCTGGTAACCACAGTACAAGTGTGCAGAGCTGGGCCTTCA
TTCCACAGGACATAATGCATGGGCAATATAATGTTCTACAGAAAGATCATGCCAAGACCAGTGATCCAGGAAGATCATGGAAAATAATGC
ACATCAGTGAACAAGAGGAACCCATAGAGCTTAAATGTGTGTCTGTGACAGGATTCACTGCACTGTTTACTTGGGAAGTGGAAAGGATGG
GCTATACCATTACCCTCTGGGATTTGGAGACCCAGGGCATGCAGTGTTTTTCCCTTGGCACAAAGTGTATTCCTGTAGACAGTAGTGGAG
ACCAGCAGCTGTGCTTTGTTTTGACAGAGAATGGACTCTCTCTGATTTTGTTTGGTTTGACTCAAGAAGAGTTTTTAAACAGACTCATGA
TCCATGGAAGTGCCAGCACTGTGGACACTCTTTGTCATCTCAATGGCTGGGGAAGGTGCTCAATTCCCATACATGCACTAGAGGCCGGGA
TAGAAAATCGTCAGCTGGACACAGTAAATTTCTTTTTGAAGAGCAAGGAAAATCTTTTTAATCCATCCTCAAAATCTTCTGTATCTGATC
AGTTTGATCACTTGTCATCCCATTTATATTTAAGAATCTATGGGGTGGAGCTGTTCCTGAAGGTTGCCGGCCTGGGCCCTGTGGAGTACT
TGTCTTCCGGATGGAACTTGTTTGACTTCTCCGTGACAGTGTTCGCCTTCCTGGGACTGCTGGCGCTGGCCCTCAACATGGAGCCCTTCT
ATTTCATCGTGGTCCTGCGCCCCCTCCAGCTGCTGAGGTTGTTTAAGTTGAAGGAGCGCTACCGCAACGTGCTGGACACCATGTTCGAGC
TGCTGCCCCGGATGGCCAGCCTGGGCCTCACCCTGCTCATCTTTTACTACTCCTTCGCCATCGTGGGCATGGAGTTCTTCTGCGGGATCG
TCTTCCCCAACTGCTGCAACACGAGTACAGTGGCAGATGCCTACCGCTGGCGCAACCACACCGTGGGCAACAGGACCGTGGTGGAGGAAG
GCTACTATTATCTCAATAATTTTGACAACATCCTCAACAGCTTTGTGACCCTGTTTGAGCTCACAGTTGTCAACAACTGGTACATCATCA
TGGAAGGCGTCACCTCTCAGACCTCCCACTGGAGCCGCCTCTACTTCATGACCTTTTACATTGTGACCATGGTGGTGATGACGATCATTG
TCGCCTTTATCCTCGAGGCCTTCGTCTTCCGAATGAACTACAGCCGCAAGAACCAGGACTCGGAAGTTGATGGTGGCATCACCCTTGAGA
AGGAAATCTCCAAAGAAGAGCTGGTTGCCGTCCTGGAGCTCTACCGGGAGGCACGGGGGGCCTCCTCGGATGTCACCAGGCTGCTGGAGA
CCCTCTCCCAGATGGAGAGATACCAGCAACATTCCATGGTGTTTCTGGGACGGCGATCAAGGACCAAGAGCGACCTGAGCCTGAAGATGT
ACCAGGAGGAGATCCAGGAGTGGTATGAGGAGCATGCCAGGGAGCAAGAGCAGCAGCGACAACTCAGCAGCAGTGCAGCCCCCGCCGCCC
AGCAGCCCCCAGGCAGCCGCCAGCGCTCCCAGACCGTTACCTAGCCCAGCGCCCGAAAGCCGTCTCTTCTATGCAATAACACAATAGTAT
TACTCTACTGCGATGTACGGAACTGCGGTGTGTGTACACATACTCACGTATATGCACATATTTATATACAGGAAGAAAAAAGACAGACAA
GATGGGGCTTGGTTTATAACCACCTTGCCCTGTCTTCCTTAACTCCAGAAGCCAGTTTGGTGAGGGGTGGGGGTGCGGCCACCAGGTCTG
AGCTCTTCCTACTGTGGAAGGCTCCAGAAGGCCCTTCACAAGGAGACCCCTCACCTGGATCCAGTCGACTGCGGGGCTTGCCCCTCATGT
GGGCTGGCCTCCATCGGCCACGTCCAAAGCTGTCACTGCTACTGCTTCAGGCTCACATCCCCCCGACCTGATGGCGTGCCCGCCCCCTCT
CCCTGCGGCCCATGCCACAGGTTTCTGTGTTTTGCTTTAGGGACAGAACCACTTAGGAAGGAAAGAACTCCCGGTCTCCAGGGTGGTATT
TCAGTGTCTGTGATAATGTCACGCAACACCTCTTCGGGGACCAGTGCCCAGGATCTAATGGAAGCGGAATTGGGGCAACTGGGCCCATGT
GGCCAGAGCTCAGTTAGCCAGTGCCGGGCGGCCACAGATTACACTGACCAATCTCCTCCCTTGGCTCTGCAAGCCTCCCACCCAGCCTTC
TCTGGCTTAACCCTTGTTGGCGAAAACTCTTCCACAGTGGCCTCCTTGGGGACCCAGAACCCGGAGGAAGGGGCATGAGGCAGGAAGTGG
GGCCGATGTCTGCAACCCAGACCACTTCGTGGAATGGGCTCTTGACCAAATCCCTTTTTTTGCGATTTACCCGTTCAAGCAAAACAACGT
TTTGGTTAACTAAGGATTGTGCTAAAGCCGATACCAGGTCCTTCACACGTGTGCACTAGGAACAGGAGCGAACAGCACAGAGAGACGCTC
CCTGTGGGACGCAGCAGCCCCGTGGCCCCGGCCCAGTTCCCAGCCACCCTCCCTGGCTCTGCTCACACCAGAGATTTCCATAGCAGGAGC
GGTTGGTGCAGAAGTAGGTTCAGATGAACCTCAGTTAACGTCGCCACCCCTCCTCCCACCATGGTACCCTGTAGGAGCCCTGTATGACAT
CTGAGCGTGGTGGAGGTAGGAGGGTTGCCAGCTGCAGTGACCCTGCCACAGAGGCAGGGTCAGTGCAGAGGTCGCTTTGGTTCCGCTTCC
CTGGGCCACAGAACGGAACACAGCATAGGTTCTGCAGCAGGAGCCGCAGTGGCAGGATGGAGGGTGCGAAGGGCAAGGAGTGCACTGCTG
GGCATTCCTGGCCAGCCCCGGCCCTCTGGTGCCTGCTTCCTGTGACTTCAGAAGGCAGGTGGACAGAGCCTCCCTCTGGCCTTGTCCTCT
TCCCAGCCACAGAACGGGCAGGGTGGCACCCGACCCCAGGGGAGCAGTACCTGGTCCCCCACCCCCTCCTCCCAACCACCTCCAAGGCCA
AGCTGGGTCCCATAGCCAGCACGGCATGGTTCTCCCCTTCCCCCCTTCCCAGGTCAGGGGAGTTGGACAAGTAGCAGGTGTTTGTTTTTA
AAGCACAGCCCTTTGGGAAAGCAACACATTATTGAGACTCACTGTGATTCCCCCGGGAGTCAGACTGGCTTTGTCCTCTTCCTCTCTGGA
GGGCCATGGGCCATCAGCAGGAGCTCCACATCGAGCCCCAGGCCAGAACCCCCTCCCTTTCACAGAGAGGGAACTTTATTGCACAATTGG
GTGCCTTTTAGCTTTTGTGTGTTGAAATGGGCGTTTTGGAAGCAAGGGTCAGGGGACAGCTTCTAAAGGTGTGAGTCTCTGACCTGAGCA
TCTGGGCCTCGCCTGGGCCCTTCTTCCTCCCCAGGGGTGGAAACGTGGAGGGGCCAGCAGCACCCCGGGGTCTGCCCAGGGGAGTCAAGG
CCCCGAGGTGGGGGGGCCTATTCCAGGAGGAGTGGGATCTCGGCCCTGTCCAGAGCGAGTTAATGTGTCCATCTGCCCAACCCTGTCCTG
AGAAAGGACCTGGTTTTGGCCAGGACCTGACAAATACCCAATGGCAGCAGTGTCAACAGACGGGAGTCCAGCCAGGGTGGGTGCCCTTGT
CATTGAGGTTAGGGACAGCTATCCCCAGGTTATGCCTGGCCCCACCCAGCAGGGAGTTGGGGTCCCCCCACAGGCTGTGAGCTCTGTGGG
CCCTGGGATGTGATCTAGCTCAGATGCCCTCTCATCCTTGATGTCATAGTTGAGTGCACCCAAGTGGCACCCACTGGCGGCCAGGGGCAC
AGCCTGGTGGTGGTGGCAATAGAACTGTGCCCCTCCTCAGCTCCTCGCTTCCCCTCCCACAGCCCCAGCCTTACTCCACCATGCGGACAA
TCATTTTGTACGGATCACGGGAGCAATGCTGTACGGTTTTGTACACTGGTGGTTTGTTTCCTAGAAAACCCATTGTGTCTCTGGATTTCT

>85743_85743_19_SPG11-TPCN1_SPG11_chr15_44925703_ENST00000559193_TPCN1_chr12_113723694_ENST00000541517_length(amino acids)=910AA_BP=579
MAAEEGVASAASAGGSWGTAAMGRVLPMLLVPVPAEAMGQLGSRAQLRTQPEALGSLTAAGSLQVLSLTPGSRGGGRCCLEGPFWHFLWE
DSRNSSTPTEKPKLLALGENYELLIYEFNLKDGRCDATILYSCSREALQKLIDDQDISISLLSLRILSFHNNTSLLFINKCVILHIIFPE
RDAAIRVLNCFTLPLPAQAVDMIIDTQLCRGILFVLSSLGWIYIFDVVDGTYVAHVDLALHKEDMCNEQQQEPAKISSFTSLKVSQDLDV
AVIVSSSNSAVALNLNLYFRQHPGHLLCERILEDLPIQGPKGVDEDDPVNSAYNMKLAKFSFQIDRSWKAQLSSLNETIKNSKLEVSCCA
PWFQDILHLESPESGNHSTSVQSWAFIPQDIMHGQYNVLQKDHAKTSDPGRSWKIMHISEQEEPIELKCVSVTGFTALFTWEVERMGYTI
TLWDLETQGMQCFSLGTKCIPVDSSGDQQLCFVLTENGLSLILFGLTQEEFLNRLMIHGSASTVDTLCHLNGWGRCSIPIHALEAGIENR
QLDTVNFFLKSKENLFNPSSKSSVSDQFDHLSSHLYLRIYGVELFLKVAGLGPVEYLSSGWNLFDFSVTVFAFLGLLALALNMEPFYFIV
VLRPLQLLRLFKLKERYRNVLDTMFELLPRMASLGLTLLIFYYSFAIVGMEFFCGIVFPNCCNTSTVADAYRWRNHTVGNRTVVEEGYYY
LNNFDNILNSFVTLFELTVVNNWYIIMEGVTSQTSHWSRLYFMTFYIVTMVVMTIIVAFILEAFVFRMNYSRKNQDSEVDGGITLEKEIS
KEELVAVLELYREARGASSDVTRLLETLSQMERYQQHSMVFLGRRSRTKSDLSLKMYQEEIQEWYEEHAREQEQQRQLSSSAAPAAQQPP

--------------------------------------------------------------
>85743_85743_20_SPG11-TPCN1_SPG11_chr15_44925703_ENST00000559193_TPCN1_chr12_113723694_ENST00000550785_length(transcript)=5253nt_BP=1746nt
GCCGGGCCAAGATGGCTGCAGAGGAAGGGGTCGCGAGTGCTGCTTCCGCCGGCGGTAGCTGGGGCACCGCGGCCATGGGGCGGGTTCTAC
CGATGCTGTTGGTGCCAGTCCCCGCCGAGGCGATGGGGCAGCTCGGCTCCCGGGCGCAGCTGCGCACACAGCCGGAGGCTCTGGGGAGCC
TGACGGCTGCGGGCAGCCTCCAAGTGCTTTCTTTGACGCCTGGCAGCCGGGGCGGGGGTCGCTGCTGCCTGGAGGGCCCCTTCTGGCACT
TTCTATGGGAGGATTCTCGTAACAGCAGCACACCAACTGAAAAGCCCAAACTGCTCGCTCTTGGTGAAAATTATGAACTGCTTATCTATG
AATTTAATTTGAAAGATGGAAGATGTGATGCAACCATTTTGTATAGCTGTAGTAGGGAGGCATTGCAAAAGCTCATTGACGATCAAGATA
TCAGTATTTCCTTATTGTCTTTGAGAATCCTGTCATTTCACAATAACACATCATTACTGTTCATCAACAAATGTGTCATCCTACATATTA
TATTTCCTGAAAGAGATGCTGCAATTAGAGTACTCAACTGTTTCACACTTCCCTTGCCTGCACAGGCAGTGGACATGATTATTGACACGC
AGCTCTGCAGAGGAATTCTTTTTGTTTTGAGTAGTTTAGGCTGGATCTACATTTTTGATGTTGTGGATGGTACATATGTAGCTCATGTGG
ATTTAGCACTTCACAAAGAAGACATGTGTAATGAGCAGCAACAGGAGCCAGCCAAGATTTCTTCATTTACTTCACTGAAAGTTTCTCAAG
ACCTCGATGTTGCAGTGATTGTCAGCTCCTCCAACTCCGCAGTTGCTCTTAACTTAAATTTGTATTTCAGGCAACACCCAGGACACCTAC
TGTGTGAAAGAATACTAGAAGATCTTCCTATTCAAGGACCTAAGGGCGTAGATGAAGATGATCCTGTTAACTCTGCCTACAACATGAAAC
TGGCCAAGTTTTCCTTCCAAATTGATAGGTCTTGGAAAGCCCAGCTATCATCATTGAATGAAACAATAAAGAACTCCAAACTGGAGGTTT
CCTGTTGTGCTCCATGGTTCCAGGATATTTTGCATTTGGAGTCACCTGAATCTGGTAACCACAGTACAAGTGTGCAGAGCTGGGCCTTCA
TTCCACAGGACATAATGCATGGGCAATATAATGTTCTACAGAAAGATCATGCCAAGACCAGTGATCCAGGAAGATCATGGAAAATAATGC
ACATCAGTGAACAAGAGGAACCCATAGAGCTTAAATGTGTGTCTGTGACAGGATTCACTGCACTGTTTACTTGGGAAGTGGAAAGGATGG
GCTATACCATTACCCTCTGGGATTTGGAGACCCAGGGCATGCAGTGTTTTTCCCTTGGCACAAAGTGTATTCCTGTAGACAGTAGTGGAG
ACCAGCAGCTGTGCTTTGTTTTGACAGAGAATGGACTCTCTCTGATTTTGTTTGGTTTGACTCAAGAAGAGTTTTTAAACAGACTCATGA
TCCATGGAAGTGCCAGCACTGTGGACACTCTTTGTCATCTCAATGGCTGGGGAAGGTGCTCAATTCCCATACATGCACTAGAGGCCGGGA
TAGAAAATCGTCAGCTGGACACAGTAAATTTCTTTTTGAAGAGCAAGGAAAATCTTTTTAATCCATCCTCAAAATCTTCTGTATCTGATC
AGTTTGATCACTTGTCATCCCATTTATATTTAAGAATCTATGGGGTGGAGCTGTTCCTGAAGGTTGCCGGCCTGGGCCCTGTGGAGTACT
TGTCTTCCGGATGGAACTTGTTTGACTTCTCCGTGACAGTGTTCGCCTTCCTGGGACTGCTGGCGCTGGCCCTCAACATGGAGCCCTTCT
ATTTCATCGTGGTCCTGCGCCCCCTCCAGCTGCTGAGGTTGTTTAAGTTGAAGGAGCGCTACCGCAACGTGCTGGACACCATGTTCGAGC
TGCTGCCCCGGATGGCCAGCCTGGGCCTCACCCTGCTCATCTTTTACTACTCCTTCGCCATCGTGGGCATGGAGTTCTTCTGCGGGATCG
TCTTCCCCAACTGCTGCAACACGAGTACAGTGGCAGATGCCTACCGCTGGCGCAACCACACCGTGGGCAACAGGACCGTGGTGGAGGAAG
GCTACTATTATCTCAATAATTTTGACAACATCCTCAACAGCTTTGTGACCCTGTTTGAGCTCACAGTTGTCAACAACTGGTACATCATCA
TGGAAGGCGTCACCTCTCAGACCTCCCACTGGAGCCGCCTCTACTTCATGACCTTTTACATTGTGACCATGGTGGTGATGACGATCATTG
TCGCCTTTATCCTCGAGGCCTTCGTCTTCCGAATGAACTACAGCCGCAAGAACCAGGACTCGGAAGTTGATGGTGGCATCACCCTTGAGA
AGGAAATCTCCAAAGAAGAGCTGGTTGCCGTCCTGGAGCTCTACCGGGAGGCACGGGGGGCCTCCTCGGATGTCACCAGGCTGCTGGAGA
CCCTCTCCCAGATGGAGAGATACCAGCAACATTCCATGGTGTTTCTGGGACGGCGATCAAGGACCAAGAGCGACCTGAGCCTGAAGATGT
ACCAGGAGGAGATCCAGGAGTGGTATGAGGAGCATGCCAGGGAGCAAGAGCAGCAGCGACAACTCAGCAGCAGTGCAGCCCCCGCCGCCC
AGCAGCCCCCAGGCAGCCGCCAGCGCTCCCAGACCGTTACCTAGCCCAGCGCCCGAAAGCCGTCTCTTCTATGCAATAACACAATAGTAT
TACTCTACTGCGATGTACGGAACTGCGGTGTGTGTACACATACTCACGTATATGCACATATTTATATACAGGAAGAAAAAAGACAGACAA
GATGGGGCTTGGTTTATAACCACCTTGCCCTGTCTTCCTTAACTCCAGAAGCCAGTTTGGTGAGGGGTGGGGGTGCGGCCACCAGGTCTG
AGCTCTTCCTACTGTGGAAGGCTCCAGAAGGCCCTTCACAAGGAGACCCCTCACCTGGATCCAGTCGACTGCGGGGCTTGCCCCTCATGT
GGGCTGGCCTCCATCGGCCACGTCCAAAGCTGTCACTGCTACTGCTTCAGGCTCACATCCCCCCGACCTGATGGCGTGCCCGCCCCCTCT
CCCTGCGGCCCATGCCACAGGTTTCTGTGTTTTGCTTTAGGGACAGAACCACTTAGGAAGGAAAGAACTCCCGGTCTCCAGGGTGGTATT
TCAGTGTCTGTGATAATGTCACGCAACACCTCTTCGGGGACCAGTGCCCAGGATCTAATGGAAGCGGAATTGGGGCAACTGGGCCCATGT
GGCCAGAGCTCAGTTAGCCAGTGCCGGGCGGCCACAGATTACACTGACCAATCTCCTCCCTTGGCTCTGCAAGCCTCCCACCCAGCCTTC
TCTGGCTTAACCCTTGTTGGCGAAAACTCTTCCACAGTGGCCTCCTTGGGGACCCAGAACCCGGAGGAAGGGGCATGAGGCAGGAAGTGG
GGCCGATGTCTGCAACCCAGACCACTTCGTGGAATGGGCTCTTGACCAAATCCCTTTTTTTGCGATTTACCCGTTCAAGCAAAACAACGT
TTTGGTTAACTAAGGATTGTGCTAAAGCCGATACCAGGTCCTTCACACGTGTGCACTAGGAACAGGAGCGAACAGCACAGAGAGACGCTC
CCTGTGGGACGCAGCAGCCCCGTGGCCCCGGCCCAGTTCCCAGCCACCCTCCCTGGCTCTGCTCACACCAGAGATTTCCATAGCAGGAGC
GGTTGGTGCAGAAGTAGGTTCAGATGAACCTCAGTTAACGTCGCCACCCCTCCTCCCACCATGGTACCCTGTAGGAGCCCTGTATGACAT
CTGAGCGTGGTGGAGGTAGGAGGGTTGCCAGCTGCAGTGACCCTGCCACAGAGGCAGGGTCAGTGCAGAGGTCGCTTTGGTTCCGCTTCC
CTGGGCCACAGAACGGAACACAGCATAGGTTCTGCAGCAGGAGCCGCAGTGGCAGGATGGAGGGTGCGAAGGGCAAGGAGTGCACTGCTG
GGCATTCCTGGCCAGCCCCGGCCCTCTGGTGCCTGCTTCCTGTGACTTCAGAAGGCAGGTGGACAGAGCCTCCCTCTGGCCTTGTCCTCT
TCCCAGCCACAGAACGGGCAGGGTGGCACCCGACCCCAGGGGAGCAGTACCTGGTCCCCCACCCCCTCCTCCCAACCACCTCCAAGGCCA
AGCTGGGTCCCATAGCCAGCACGGCATGGTTCTCCCCTTCCCCCCTTCCCAGGTCAGGGGAGTTGGACAAGTAGCAGGTGTTTGTTTTTA
AAGCACAGCCCTTTGGGAAAGCAACACATTATTGAGACTCACTGTGATTCCCCCGGGAGTCAGACTGGCTTTGTCCTCTTCCTCTCTGGA
GGGCCATGGGCCATCAGCAGGAGCTCCACATCGAGCCCCAGGCCAGAACCCCCTCCCTTTCACAGAGAGGGAACTTTATTGCACAATTGG
GTGCCTTTTAGCTTTTGTGTGTTGAAATGGGCGTTTTGGAAGCAAGGGTCAGGGGACAGCTTCTAAAGGTGTGAGTCTCTGACCTGAGCA
TCTGGGCCTCGCCTGGGCCCTTCTTCCTCCCCAGGGGTGGAAACGTGGAGGGGCCAGCAGCACCCCGGGGTCTGCCCAGGGGAGTCAAGG
CCCCGAGGTGGGGGGGCCTATTCCAGGAGGAGTGGGATCTCGGCCCTGTCCAGAGCGAGTTAATGTGTCCATCTGCCCAACCCTGTCCTG
AGAAAGGACCTGGTTTTGGCCAGGACCTGACAAATACCCAATGGCAGCAGTGTCAACAGACGGGAGTCCAGCCAGGGTGGGTGCCCTTGT
CATTGAGGTTAGGGACAGCTATCCCCAGGTTATGCCTGGCCCCACCCAGCAGGGAGTTGGGGTCCCCCCACAGGCTGTGAGCTCTGTGGG
CCCTGGGATGTGATCTAGCTCAGATGCCCTCTCATCCTTGATGTCATAGTTGAGTGCACCCAAGTGGCACCCACTGGCGGCCAGGGGCAC
AGCCTGGTGGTGGTGGCAATAGAACTGTGCCCCTCCTCAGCTCCTCGCTTCCCCTCCCACAGCCCCAGCCTTACTCCACCATGCGGACAA
TCATTTTGTACGGATCACGGGAGCAATGCTGTACGGTTTTGTACACTGGTGGTTTGTTTCCTAGAAAACCCATTGTGTCTCTGGATTTCT

>85743_85743_20_SPG11-TPCN1_SPG11_chr15_44925703_ENST00000559193_TPCN1_chr12_113723694_ENST00000550785_length(amino acids)=910AA_BP=579
MAAEEGVASAASAGGSWGTAAMGRVLPMLLVPVPAEAMGQLGSRAQLRTQPEALGSLTAAGSLQVLSLTPGSRGGGRCCLEGPFWHFLWE
DSRNSSTPTEKPKLLALGENYELLIYEFNLKDGRCDATILYSCSREALQKLIDDQDISISLLSLRILSFHNNTSLLFINKCVILHIIFPE
RDAAIRVLNCFTLPLPAQAVDMIIDTQLCRGILFVLSSLGWIYIFDVVDGTYVAHVDLALHKEDMCNEQQQEPAKISSFTSLKVSQDLDV
AVIVSSSNSAVALNLNLYFRQHPGHLLCERILEDLPIQGPKGVDEDDPVNSAYNMKLAKFSFQIDRSWKAQLSSLNETIKNSKLEVSCCA
PWFQDILHLESPESGNHSTSVQSWAFIPQDIMHGQYNVLQKDHAKTSDPGRSWKIMHISEQEEPIELKCVSVTGFTALFTWEVERMGYTI
TLWDLETQGMQCFSLGTKCIPVDSSGDQQLCFVLTENGLSLILFGLTQEEFLNRLMIHGSASTVDTLCHLNGWGRCSIPIHALEAGIENR
QLDTVNFFLKSKENLFNPSSKSSVSDQFDHLSSHLYLRIYGVELFLKVAGLGPVEYLSSGWNLFDFSVTVFAFLGLLALALNMEPFYFIV
VLRPLQLLRLFKLKERYRNVLDTMFELLPRMASLGLTLLIFYYSFAIVGMEFFCGIVFPNCCNTSTVADAYRWRNHTVGNRTVVEEGYYY
LNNFDNILNSFVTLFELTVVNNWYIIMEGVTSQTSHWSRLYFMTFYIVTMVVMTIIVAFILEAFVFRMNYSRKNQDSEVDGGITLEKEIS
KEELVAVLELYREARGASSDVTRLLETLSQMERYQQHSMVFLGRRSRTKSDLSLKMYQEEIQEWYEEHAREQEQQRQLSSSAAPAAQQPP

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Fusion Gene PPI Analysis for SPG11-TPCN1


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for SPG11-TPCN1


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for SPG11-TPCN1


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource