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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:SPIDR-FNTA (FusionGDB2 ID:85789)

Fusion Gene Summary for SPIDR-FNTA

check button Fusion gene summary
Fusion gene informationFusion gene name: SPIDR-FNTA
Fusion gene ID: 85789
HgeneTgene
Gene symbol

SPIDR

FNTA

Gene ID

23514

2339

Gene namescaffold protein involved in DNA repairfarnesyltransferase, CAAX box, alpha
SynonymsKIAA0146FPTA|PGGT1A|PTAR2
Cytomap

8q11.21

8p11.21

Type of geneprotein-codingprotein-coding
DescriptionDNA repair-scaffolding proteinscaffolding protein involved in DNA repairprotein farnesyltransferase/geranylgeranyltransferase type-1 subunit alphaFTase-alphaGGTase-I-alphafarnesyl-protein transferase alpha-subunitprotein prenyltransferase alpha subunit repeat containing 2ras proteins prenyltransferase subunit alphatype
Modification date2020032020200313
UniProtAcc

Q14159

P49354

Ensembl transtripts involved in fusion geneENST00000521214, ENST00000297423, 
ENST00000518074, ENST00000541342, 
ENST00000517693, ENST00000518060, 
ENST00000302279, ENST00000342116, 
ENST00000524546, ENST00000529687, 
Fusion gene scores* DoF score24 X 12 X 15=432010 X 11 X 7=770
# samples 2714
** MAII scorelog2(27/4320*10)=-4
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(14/770*10)=-2.4594316186373
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: SPIDR [Title/Abstract] AND FNTA [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointFNTA(42932507)-SPIDR(48192450), # samples:1
SPIDR(48353104)-FNTA(42938261), # samples:1
Anticipated loss of major functional domain due to fusion event.FNTA-SPIDR seems lost the major protein functional domain in Hgene partner, which is a essential gene due to the frame-shifted ORF.
FNTA-SPIDR seems lost the major protein functional domain in Hgene partner, which is a IUPHAR drug target due to the frame-shifted ORF.
FNTA-SPIDR seems lost the major protein functional domain in Tgene partner, which is a essential gene due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneSPIDR

GO:0006974

cellular response to DNA damage stimulus

23509288

HgeneSPIDR

GO:0010569

regulation of double-strand break repair via homologous recombination

23754376

HgeneSPIDR

GO:0031334

positive regulation of protein complex assembly

23509288

HgeneSPIDR

GO:0070202

regulation of establishment of protein localization to chromosome

23509288

HgeneSPIDR

GO:0071479

cellular response to ionizing radiation

23509288|23754376

HgeneSPIDR

GO:0072711

cellular response to hydroxyurea

23509288

HgeneSPIDR

GO:0072757

cellular response to camptothecin

23509288

TgeneFNTA

GO:0018343

protein farnesylation

16893176|19228685

TgeneFNTA

GO:0018344

protein geranylgeranylation

16893176

TgeneFNTA

GO:0090044

positive regulation of tubulin deacetylation

19228685

TgeneFNTA

GO:0090045

positive regulation of deacetylase activity

19228685


check buttonFusion gene breakpoints across SPIDR (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across FNTA (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4LUADTCGA-69-7760-01ASPIDRchr8

48353104

+FNTAchr8

42938261

+


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Fusion Gene ORF analysis for SPIDR-FNTA

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
3UTR-3CDSENST00000521214ENST00000302279SPIDRchr8

48353104

+FNTAchr8

42938261

+
3UTR-3CDSENST00000521214ENST00000342116SPIDRchr8

48353104

+FNTAchr8

42938261

+
3UTR-intronENST00000521214ENST00000524546SPIDRchr8

48353104

+FNTAchr8

42938261

+
3UTR-intronENST00000521214ENST00000529687SPIDRchr8

48353104

+FNTAchr8

42938261

+
5CDS-intronENST00000297423ENST00000524546SPIDRchr8

48353104

+FNTAchr8

42938261

+
5CDS-intronENST00000297423ENST00000529687SPIDRchr8

48353104

+FNTAchr8

42938261

+
5CDS-intronENST00000518074ENST00000524546SPIDRchr8

48353104

+FNTAchr8

42938261

+
5CDS-intronENST00000518074ENST00000529687SPIDRchr8

48353104

+FNTAchr8

42938261

+
5CDS-intronENST00000541342ENST00000524546SPIDRchr8

48353104

+FNTAchr8

42938261

+
5CDS-intronENST00000541342ENST00000529687SPIDRchr8

48353104

+FNTAchr8

42938261

+
In-frameENST00000297423ENST00000302279SPIDRchr8

48353104

+FNTAchr8

42938261

+
In-frameENST00000297423ENST00000342116SPIDRchr8

48353104

+FNTAchr8

42938261

+
In-frameENST00000518074ENST00000302279SPIDRchr8

48353104

+FNTAchr8

42938261

+
In-frameENST00000518074ENST00000342116SPIDRchr8

48353104

+FNTAchr8

42938261

+
In-frameENST00000541342ENST00000302279SPIDRchr8

48353104

+FNTAchr8

42938261

+
In-frameENST00000541342ENST00000342116SPIDRchr8

48353104

+FNTAchr8

42938261

+
intron-3CDSENST00000517693ENST00000302279SPIDRchr8

48353104

+FNTAchr8

42938261

+
intron-3CDSENST00000517693ENST00000342116SPIDRchr8

48353104

+FNTAchr8

42938261

+
intron-3CDSENST00000518060ENST00000302279SPIDRchr8

48353104

+FNTAchr8

42938261

+
intron-3CDSENST00000518060ENST00000342116SPIDRchr8

48353104

+FNTAchr8

42938261

+
intron-intronENST00000517693ENST00000524546SPIDRchr8

48353104

+FNTAchr8

42938261

+
intron-intronENST00000517693ENST00000529687SPIDRchr8

48353104

+FNTAchr8

42938261

+
intron-intronENST00000518060ENST00000524546SPIDRchr8

48353104

+FNTAchr8

42938261

+
intron-intronENST00000518060ENST00000529687SPIDRchr8

48353104

+FNTAchr8

42938261

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000297423SPIDRchr848353104+ENST00000302279FNTAchr842938261+23451481511481476
ENST00000297423SPIDRchr848353104+ENST00000342116FNTAchr842938261+23371481511481476
ENST00000518074SPIDRchr848353104+ENST00000302279FNTAchr842938261+195210881711088305
ENST00000518074SPIDRchr848353104+ENST00000342116FNTAchr842938261+194410881711088305
ENST00000541342SPIDRchr848353104+ENST00000302279FNTAchr842938261+189710331461033295
ENST00000541342SPIDRchr848353104+ENST00000342116FNTAchr842938261+188910331461033295

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000297423ENST00000302279SPIDRchr848353104+FNTAchr842938261+0.011648850.98835117
ENST00000297423ENST00000342116SPIDRchr848353104+FNTAchr842938261+0.0120284590.9879716
ENST00000518074ENST00000302279SPIDRchr848353104+FNTAchr842938261+0.0026039310.9973961
ENST00000518074ENST00000342116SPIDRchr848353104+FNTAchr842938261+0.0026491070.99735093
ENST00000541342ENST00000302279SPIDRchr848353104+FNTAchr842938261+0.0026024620.99739754
ENST00000541342ENST00000342116SPIDRchr848353104+FNTAchr842938261+0.0026611060.99733883

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Fusion Genomic Features for SPIDR-FNTA


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
SPIDRchr848353104+FNTAchr842938260+6.83E-060.9999932
SPIDRchr848353104+FNTAchr842938260+6.83E-060.9999932

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for SPIDR-FNTA


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr8:42932507/chr8:48192450)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
SPIDR

Q14159

FNTA

P49354

FUNCTION: Plays a role in DNA double-strand break (DBS) repair via homologous recombination (HR). Serves as a scaffolding protein that helps to promote the recruitment of DNA-processing enzymes like the helicase BLM and recombinase RAD51 to site of DNA damage, and hence contributes to maintain genomic integrity. {ECO:0000269|PubMed:23509288, ECO:0000269|PubMed:23754376}.FUNCTION: Essential subunit of both the farnesyltransferase and the geranylgeranyltransferase complex. Contributes to the transfer of a farnesyl or geranylgeranyl moiety from farnesyl or geranylgeranyl diphosphate to a cysteine at the fourth position from the C-terminus of several proteins having the C-terminal sequence Cys-aliphatic-aliphatic-X. May positively regulate neuromuscular junction development downstream of MUSK via its function in RAC1 prenylation and activation. {ECO:0000269|PubMed:12036349, ECO:0000269|PubMed:12825937, ECO:0000269|PubMed:16893176, ECO:0000269|PubMed:19246009, ECO:0000269|PubMed:8419339, ECO:0000269|PubMed:8494894}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneFNTAchr8:48353104chr8:42938261ENST0000034211637216_249193313.0RepeatNote=PFTA 4
TgeneFNTAchr8:48353104chr8:42938261ENST0000034211637255_289193313.0RepeatNote=PFTA 5

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneFNTAchr8:48353104chr8:42938261ENST000003022795922_31260380.0Compositional biasNote=Pro-rich
TgeneFNTAchr8:48353104chr8:42938261ENST000003421163722_31193313.0Compositional biasNote=Pro-rich
TgeneFNTAchr8:48353104chr8:42938261ENST0000030227959112_146260380.0RepeatNote=PFTA 1
TgeneFNTAchr8:48353104chr8:42938261ENST0000030227959147_180260380.0RepeatNote=PFTA 2
TgeneFNTAchr8:48353104chr8:42938261ENST0000030227959181_215260380.0RepeatNote=PFTA 3
TgeneFNTAchr8:48353104chr8:42938261ENST0000030227959216_249260380.0RepeatNote=PFTA 4
TgeneFNTAchr8:48353104chr8:42938261ENST0000030227959255_289260380.0RepeatNote=PFTA 5
TgeneFNTAchr8:48353104chr8:42938261ENST0000034211637112_146193313.0RepeatNote=PFTA 1
TgeneFNTAchr8:48353104chr8:42938261ENST0000034211637147_180193313.0RepeatNote=PFTA 2
TgeneFNTAchr8:48353104chr8:42938261ENST0000034211637181_215193313.0RepeatNote=PFTA 3


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Fusion Gene Sequence for SPIDR-FNTA


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>85789_85789_1_SPIDR-FNTA_SPIDR_chr8_48353104_ENST00000297423_FNTA_chr8_42938261_ENST00000302279_length(transcript)=2345nt_BP=1481nt
AGTTGTTGCCTGACAACACAGACGACAGTAACTTAATTCGAAAGACAATACTTGGAGGCGGCCCCCGCTCCAGGCACCAGCCCAGCAGCT
CCCCCGAACTCCCCAGGAGCTCGCGGGCGAGCAACGCCACAGCCCAGAGCGAGCTCCGCGGAACCCCCAGCCCCGGGGAAGGAAGCTCGA
CTCTCCGCGGGGCACTCCTTCCGGGCTCCGGGCCCGACTAGGCCATCCGGGAGGCCCTGGAGCGCCGGGGCCGGAGAAGCCCTGCCCCCC
GCCGAAGCCCCGCCCTGCGCCCGAGCGCCCGCCAATGGCAGGGCGCGGTGCGGCGCGCCGAGGTGGGACGGCGGCGCGCTGAGGAGGCGG
TGCGCTCAGGCGGCGCTCCCGGAGATGCCCCGCGGCAGCCGCGCTCGGGGCTCTAAGAGAAAAAGGAGTTGGAATACAGAATGCCCATCC
TTTCCAGGAGAAAGACCACTGCAGGTCAGAAGAGCAGGTCTCAGGACAGCAGGGGCAGCTGCCTCTCTCTCTGAAGCATGGCTCAGGTGT
GGAGAAGGGTTTCAGAACACTTCTGGGAATCCGTCATTAACAGCTGAAGAGAAGACGATTACAGAAAAGCACCTTGAATTATGCCCTAGA
CCCAAGCAAGAAACCACCACATCTAAAAGCACCAGTGGGCTTACAGACATAACATGGAGCTCCAGTGGAAGTGATTTGTCGGATGAAGAT
AAGACACTTTCTCAGTTACAGAGAGATGAATTACAGTTTATCGACTGGGAGATTGACAGTGACAGGGCAGAGGCTAGTGACTGTGATGAA
TTTGAAGATGACGAGGGTGCTGTGGAAATCTCAGACTGTGCTTCTTGTGCAAGTAATCAGTCTTTGACAAGTGATGAGAAGCTGTCGGAG
CTTCCCAAGCCAAGTTCTATAGAAATTTTAGAGTATTCATCAGATAGTGAAAAAGAAGATGATTTGGAAAATGTCCTACTCATTGATTCA
GAATCCCCTCACAAATACCACGTGCAGTTTGCATCGGATGCAAGACAGATTATGGAGAGACTGATAGATCCAAGGACAAAATCAACAGAG
ACCATTTTGCATACACCTCAGAAACCCACAGCTAAGTTTCCCAGGACTCCAGAAAATTCAGCAAAGAAGAAGCTTTTAAGAGGTGGACTA
GCAGAAAGACTAAATGGACTGCAGAATCGAGAGAGATCTGCTATTTCTTTGTGGAGACATCAATGTATTTCTTACCAAAAGACACTTTCA
GGTAGAAAATCTGGTGTATTAACTGTGAAAATTTTAGAGCTGCATGAGGAATGTGCCATGCAAGTTGCCATGTGTGAGCAGTTATTGGGG
TCACCAGCCACCAGCTCCTCCCAAAGTGTGGCTCCCAGGCCTGGAGCTGGCCTGAAAGTTCTCTTCACCAAGGAGACTGCAGGCTACCTC
AGGGGCCGTCCCCAGGACACTGTCCGGATCTTCCCTCCCTGATACACTCTGGAAATGATTAAACTAGTACCACATAATGAAAGTGCATGG
AACTATTTGAAAGGGATTTTGCAGGATCGTGGTCTTTCCAAATATCCTAATCTGTTAAATCAATTACTTGATTTACAACCAAGTCATAGT
TCCCCCTACCTAATTGCCTTTCTTGTGGATATCTATGAAGACATGCTAGAAAATCAGTGTGACAATAAGGAAGACATTCTTAATAAAGCA
TTAGAGTTATGTGAAATCCTAGCTAAAGAAAAGGACACTATAAGAAAGGAATATTGGAGATACATTGGAAGATCCCTTCAAAGCAAACAC
AGCACAGAAAATGACTCACCAACAAATGTACAGCAATAACACCATCCAGAAGAACTTGATGGAATGCTTTTATTTTTTATTAAGGGACCC
TGCAGGAGTTTCACACGAGAGTGGTCCTTCCCTTTGCCTGTGGTGTAAAAGTGCATCACACAGGTATTGCTTTTTAACAAGAACTGATGC
TCCTTGGGTGCTGCTGCTACTCAGACTAGCTCTAAGTAATGTGATTCTTCTAAAGCAAAGTCATTGGATGGGAGGAGGAAGAAAAAGTCC
CATAAAGGAACTTTTGTAGTCTTATCAACATATAATCTAATCCCTTAGCATCAGCTCCTCCCTCAGTGGTACATGCGTCAAGATTTGTAG
CAGTAATAACTGCAGGTCACTTGTATGTAATGGATGTGAGGTAGCCGAAGTTTGGTTCAGTAAGCAGGGAATACAGTCGTTCCATCAGAG
CTGGTCTGCACACTCACATTATCTTGCTATCACTGTAACCAACTAATGCCAAAAGAACGGTTTTGTAATAAAATTATAGCTGTATCTAAA

>85789_85789_1_SPIDR-FNTA_SPIDR_chr8_48353104_ENST00000297423_FNTA_chr8_42938261_ENST00000302279_length(amino acids)=476AA_BP=
MEAAPAPGTSPAAPPNSPGARGRATPQPRASSAEPPAPGKEARLSAGHSFRAPGPTRPSGRPWSAGAGEALPPAEAPPCARAPANGRARC
GAPRWDGGALRRRCAQAALPEMPRGSRARGSKRKRSWNTECPSFPGERPLQVRRAGLRTAGAAASLSEAWLRCGEGFQNTSGNPSLTAEE
KTITEKHLELCPRPKQETTTSKSTSGLTDITWSSSGSDLSDEDKTLSQLQRDELQFIDWEIDSDRAEASDCDEFEDDEGAVEISDCASCA
SNQSLTSDEKLSELPKPSSIEILEYSSDSEKEDDLENVLLIDSESPHKYHVQFASDARQIMERLIDPRTKSTETILHTPQKPTAKFPRTP
ENSAKKKLLRGGLAERLNGLQNRERSAISLWRHQCISYQKTLSGRKSGVLTVKILELHEECAMQVAMCEQLLGSPATSSSQSVAPRPGAG

--------------------------------------------------------------
>85789_85789_2_SPIDR-FNTA_SPIDR_chr8_48353104_ENST00000297423_FNTA_chr8_42938261_ENST00000342116_length(transcript)=2337nt_BP=1481nt
AGTTGTTGCCTGACAACACAGACGACAGTAACTTAATTCGAAAGACAATACTTGGAGGCGGCCCCCGCTCCAGGCACCAGCCCAGCAGCT
CCCCCGAACTCCCCAGGAGCTCGCGGGCGAGCAACGCCACAGCCCAGAGCGAGCTCCGCGGAACCCCCAGCCCCGGGGAAGGAAGCTCGA
CTCTCCGCGGGGCACTCCTTCCGGGCTCCGGGCCCGACTAGGCCATCCGGGAGGCCCTGGAGCGCCGGGGCCGGAGAAGCCCTGCCCCCC
GCCGAAGCCCCGCCCTGCGCCCGAGCGCCCGCCAATGGCAGGGCGCGGTGCGGCGCGCCGAGGTGGGACGGCGGCGCGCTGAGGAGGCGG
TGCGCTCAGGCGGCGCTCCCGGAGATGCCCCGCGGCAGCCGCGCTCGGGGCTCTAAGAGAAAAAGGAGTTGGAATACAGAATGCCCATCC
TTTCCAGGAGAAAGACCACTGCAGGTCAGAAGAGCAGGTCTCAGGACAGCAGGGGCAGCTGCCTCTCTCTCTGAAGCATGGCTCAGGTGT
GGAGAAGGGTTTCAGAACACTTCTGGGAATCCGTCATTAACAGCTGAAGAGAAGACGATTACAGAAAAGCACCTTGAATTATGCCCTAGA
CCCAAGCAAGAAACCACCACATCTAAAAGCACCAGTGGGCTTACAGACATAACATGGAGCTCCAGTGGAAGTGATTTGTCGGATGAAGAT
AAGACACTTTCTCAGTTACAGAGAGATGAATTACAGTTTATCGACTGGGAGATTGACAGTGACAGGGCAGAGGCTAGTGACTGTGATGAA
TTTGAAGATGACGAGGGTGCTGTGGAAATCTCAGACTGTGCTTCTTGTGCAAGTAATCAGTCTTTGACAAGTGATGAGAAGCTGTCGGAG
CTTCCCAAGCCAAGTTCTATAGAAATTTTAGAGTATTCATCAGATAGTGAAAAAGAAGATGATTTGGAAAATGTCCTACTCATTGATTCA
GAATCCCCTCACAAATACCACGTGCAGTTTGCATCGGATGCAAGACAGATTATGGAGAGACTGATAGATCCAAGGACAAAATCAACAGAG
ACCATTTTGCATACACCTCAGAAACCCACAGCTAAGTTTCCCAGGACTCCAGAAAATTCAGCAAAGAAGAAGCTTTTAAGAGGTGGACTA
GCAGAAAGACTAAATGGACTGCAGAATCGAGAGAGATCTGCTATTTCTTTGTGGAGACATCAATGTATTTCTTACCAAAAGACACTTTCA
GGTAGAAAATCTGGTGTATTAACTGTGAAAATTTTAGAGCTGCATGAGGAATGTGCCATGCAAGTTGCCATGTGTGAGCAGTTATTGGGG
TCACCAGCCACCAGCTCCTCCCAAAGTGTGGCTCCCAGGCCTGGAGCTGGCCTGAAAGTTCTCTTCACCAAGGAGACTGCAGGCTACCTC
AGGGGCCGTCCCCAGGACACTGTCCGGATCTTCCCTCCCTGATACACTCTGGAAATGATTAAACTAGTACCACATAATGAAAGTGCATGG
AACTATTTGAAAGGGATTTTGCAGGATCGTGGTCTTTCCAAATATCCTAATCTGTTAAATCAATTACTTGATTTACAACCAAGTCATAGT
TCCCCCTACCTAATTGCCTTTCTTGTGGATATCTATGAAGACATGCTAGAAAATCAGTGTGACAATAAGGAAGACATTCTTAATAAAGCA
TTAGAGTTATGTGAAATCCTAGCTAAAGAAAAGGACACTATAAGAAAGGAATATTGGAGATACATTGGAAGATCCCTTCAAAGCAAACAC
AGCACAGAAAATGACTCACCAACAAATGTACAGCAATAACACCATCCAGAAGAACTTGATGGAATGCTTTTATTTTTTATTAAGGGACCC
TGCAGGAGTTTCACACGAGAGTGGTCCTTCCCTTTGCCTGTGGTGTAAAAGTGCATCACACAGGTATTGCTTTTTAACAAGAACTGATGC
TCCTTGGGTGCTGCTGCTACTCAGACTAGCTCTAAGTAATGTGATTCTTCTAAAGCAAAGTCATTGGATGGGAGGAGGAAGAAAAAGTCC
CATAAAGGAACTTTTGTAGTCTTATCAACATATAATCTAATCCCTTAGCATCAGCTCCTCCCTCAGTGGTACATGCGTCAAGATTTGTAG
CAGTAATAACTGCAGGTCACTTGTATGTAATGGATGTGAGGTAGCCGAAGTTTGGTTCAGTAAGCAGGGAATACAGTCGTTCCATCAGAG

>85789_85789_2_SPIDR-FNTA_SPIDR_chr8_48353104_ENST00000297423_FNTA_chr8_42938261_ENST00000342116_length(amino acids)=476AA_BP=
MEAAPAPGTSPAAPPNSPGARGRATPQPRASSAEPPAPGKEARLSAGHSFRAPGPTRPSGRPWSAGAGEALPPAEAPPCARAPANGRARC
GAPRWDGGALRRRCAQAALPEMPRGSRARGSKRKRSWNTECPSFPGERPLQVRRAGLRTAGAAASLSEAWLRCGEGFQNTSGNPSLTAEE
KTITEKHLELCPRPKQETTTSKSTSGLTDITWSSSGSDLSDEDKTLSQLQRDELQFIDWEIDSDRAEASDCDEFEDDEGAVEISDCASCA
SNQSLTSDEKLSELPKPSSIEILEYSSDSEKEDDLENVLLIDSESPHKYHVQFASDARQIMERLIDPRTKSTETILHTPQKPTAKFPRTP
ENSAKKKLLRGGLAERLNGLQNRERSAISLWRHQCISYQKTLSGRKSGVLTVKILELHEECAMQVAMCEQLLGSPATSSSQSVAPRPGAG

--------------------------------------------------------------
>85789_85789_3_SPIDR-FNTA_SPIDR_chr8_48353104_ENST00000518074_FNTA_chr8_42938261_ENST00000302279_length(transcript)=1952nt_BP=1088nt
GCGGTGCGCTCAGGCGGCGCTCCCGGAGATGCCCCGCGGCAGCCGCGCTCGGGGCTCTAAGAGAAAAAGGAGTTGGAATACAGAATGCCC
ATCCTTTCCAGGAGAAAGACCACTGCAGGTCAGAAGAGCAGGTCTCAGGACAGCAGGGGCAGCTGCCTCTCTCTCTGAAGCATGGCTCAG
TCATTAACAGCTGAAGAGAAGACGATTACAGAAAAGCACCTTGAATTATGCCCTAGACCCAAGCAAGAAACCACCACATCTAAAAGCACC
AGTGGGCTTACAGACATAACATGGAGCTCCAGTGGAAGTGATTTGTCGGATGAAGATAAGACACTTTCTCAGTTACAGAGAGATGAATTA
CAGTTTATCGACTGGGAGATTGACAGTGACAGGGCAGAGGCTAGTGACTGTGATGAATTTGAAGATGACGAGGGTGCTGTGGAAATCTCA
GACTGTGCTTCTTGTGCAAGTAATCAGTCTTTGACAAGTGATGAGAAGCTGTCGGAGCTTCCCAAGCCAAGTTCTATAGAAATTTTAGAG
TATTCATCAGATAGTGAAAAAGAAGATGATTTGGAAAATGTCCTACTCATTGATTCAGAATCCCCTCACAAATACCACGTGCAGTTTGCA
TCGGATGCAAGACAGATTATGGAGAGACTGATAGATCCAAGGACAAAATCAACAGAGACCATTTTGCATACACCTCAGAAACCCACAGCT
AAGTTTCCCAGGACTCCAGAAAATTCAGCAAAGAAGAAGCTTTTAAGAGGTGGACTAGCAGAAAGACTAAATGGACTGCAGAATCGAGAG
AGATCTGCTATTTCTTTGTGGAGACATCAATGTATTTCTTACCAAAAGACACTTTCAGGTAGAAAATCTGGTGTATTAACTGTGAAAATT
TTAGAGCTGCATGAGGAATGTGCCATGCAAGTTGCCATGTGTGAGCAGTTATTGGGGTCACCAGCCACCAGCTCCTCCCAAAGTGTGGCT
CCCAGGCCTGGAGCTGGCCTGAAAGTTCTCTTCACCAAGGAGACTGCAGGCTACCTCAGGGGCCGTCCCCAGGACACTGTCCGGATCTTC
CCTCCCTGATACACTCTGGAAATGATTAAACTAGTACCACATAATGAAAGTGCATGGAACTATTTGAAAGGGATTTTGCAGGATCGTGGT
CTTTCCAAATATCCTAATCTGTTAAATCAATTACTTGATTTACAACCAAGTCATAGTTCCCCCTACCTAATTGCCTTTCTTGTGGATATC
TATGAAGACATGCTAGAAAATCAGTGTGACAATAAGGAAGACATTCTTAATAAAGCATTAGAGTTATGTGAAATCCTAGCTAAAGAAAAG
GACACTATAAGAAAGGAATATTGGAGATACATTGGAAGATCCCTTCAAAGCAAACACAGCACAGAAAATGACTCACCAACAAATGTACAG
CAATAACACCATCCAGAAGAACTTGATGGAATGCTTTTATTTTTTATTAAGGGACCCTGCAGGAGTTTCACACGAGAGTGGTCCTTCCCT
TTGCCTGTGGTGTAAAAGTGCATCACACAGGTATTGCTTTTTAACAAGAACTGATGCTCCTTGGGTGCTGCTGCTACTCAGACTAGCTCT
AAGTAATGTGATTCTTCTAAAGCAAAGTCATTGGATGGGAGGAGGAAGAAAAAGTCCCATAAAGGAACTTTTGTAGTCTTATCAACATAT
AATCTAATCCCTTAGCATCAGCTCCTCCCTCAGTGGTACATGCGTCAAGATTTGTAGCAGTAATAACTGCAGGTCACTTGTATGTAATGG
ATGTGAGGTAGCCGAAGTTTGGTTCAGTAAGCAGGGAATACAGTCGTTCCATCAGAGCTGGTCTGCACACTCACATTATCTTGCTATCAC

>85789_85789_3_SPIDR-FNTA_SPIDR_chr8_48353104_ENST00000518074_FNTA_chr8_42938261_ENST00000302279_length(amino acids)=305AA_BP=
MAQSLTAEEKTITEKHLELCPRPKQETTTSKSTSGLTDITWSSSGSDLSDEDKTLSQLQRDELQFIDWEIDSDRAEASDCDEFEDDEGAV
EISDCASCASNQSLTSDEKLSELPKPSSIEILEYSSDSEKEDDLENVLLIDSESPHKYHVQFASDARQIMERLIDPRTKSTETILHTPQK
PTAKFPRTPENSAKKKLLRGGLAERLNGLQNRERSAISLWRHQCISYQKTLSGRKSGVLTVKILELHEECAMQVAMCEQLLGSPATSSSQ

--------------------------------------------------------------
>85789_85789_4_SPIDR-FNTA_SPIDR_chr8_48353104_ENST00000518074_FNTA_chr8_42938261_ENST00000342116_length(transcript)=1944nt_BP=1088nt
GCGGTGCGCTCAGGCGGCGCTCCCGGAGATGCCCCGCGGCAGCCGCGCTCGGGGCTCTAAGAGAAAAAGGAGTTGGAATACAGAATGCCC
ATCCTTTCCAGGAGAAAGACCACTGCAGGTCAGAAGAGCAGGTCTCAGGACAGCAGGGGCAGCTGCCTCTCTCTCTGAAGCATGGCTCAG
TCATTAACAGCTGAAGAGAAGACGATTACAGAAAAGCACCTTGAATTATGCCCTAGACCCAAGCAAGAAACCACCACATCTAAAAGCACC
AGTGGGCTTACAGACATAACATGGAGCTCCAGTGGAAGTGATTTGTCGGATGAAGATAAGACACTTTCTCAGTTACAGAGAGATGAATTA
CAGTTTATCGACTGGGAGATTGACAGTGACAGGGCAGAGGCTAGTGACTGTGATGAATTTGAAGATGACGAGGGTGCTGTGGAAATCTCA
GACTGTGCTTCTTGTGCAAGTAATCAGTCTTTGACAAGTGATGAGAAGCTGTCGGAGCTTCCCAAGCCAAGTTCTATAGAAATTTTAGAG
TATTCATCAGATAGTGAAAAAGAAGATGATTTGGAAAATGTCCTACTCATTGATTCAGAATCCCCTCACAAATACCACGTGCAGTTTGCA
TCGGATGCAAGACAGATTATGGAGAGACTGATAGATCCAAGGACAAAATCAACAGAGACCATTTTGCATACACCTCAGAAACCCACAGCT
AAGTTTCCCAGGACTCCAGAAAATTCAGCAAAGAAGAAGCTTTTAAGAGGTGGACTAGCAGAAAGACTAAATGGACTGCAGAATCGAGAG
AGATCTGCTATTTCTTTGTGGAGACATCAATGTATTTCTTACCAAAAGACACTTTCAGGTAGAAAATCTGGTGTATTAACTGTGAAAATT
TTAGAGCTGCATGAGGAATGTGCCATGCAAGTTGCCATGTGTGAGCAGTTATTGGGGTCACCAGCCACCAGCTCCTCCCAAAGTGTGGCT
CCCAGGCCTGGAGCTGGCCTGAAAGTTCTCTTCACCAAGGAGACTGCAGGCTACCTCAGGGGCCGTCCCCAGGACACTGTCCGGATCTTC
CCTCCCTGATACACTCTGGAAATGATTAAACTAGTACCACATAATGAAAGTGCATGGAACTATTTGAAAGGGATTTTGCAGGATCGTGGT
CTTTCCAAATATCCTAATCTGTTAAATCAATTACTTGATTTACAACCAAGTCATAGTTCCCCCTACCTAATTGCCTTTCTTGTGGATATC
TATGAAGACATGCTAGAAAATCAGTGTGACAATAAGGAAGACATTCTTAATAAAGCATTAGAGTTATGTGAAATCCTAGCTAAAGAAAAG
GACACTATAAGAAAGGAATATTGGAGATACATTGGAAGATCCCTTCAAAGCAAACACAGCACAGAAAATGACTCACCAACAAATGTACAG
CAATAACACCATCCAGAAGAACTTGATGGAATGCTTTTATTTTTTATTAAGGGACCCTGCAGGAGTTTCACACGAGAGTGGTCCTTCCCT
TTGCCTGTGGTGTAAAAGTGCATCACACAGGTATTGCTTTTTAACAAGAACTGATGCTCCTTGGGTGCTGCTGCTACTCAGACTAGCTCT
AAGTAATGTGATTCTTCTAAAGCAAAGTCATTGGATGGGAGGAGGAAGAAAAAGTCCCATAAAGGAACTTTTGTAGTCTTATCAACATAT
AATCTAATCCCTTAGCATCAGCTCCTCCCTCAGTGGTACATGCGTCAAGATTTGTAGCAGTAATAACTGCAGGTCACTTGTATGTAATGG
ATGTGAGGTAGCCGAAGTTTGGTTCAGTAAGCAGGGAATACAGTCGTTCCATCAGAGCTGGTCTGCACACTCACATTATCTTGCTATCAC

>85789_85789_4_SPIDR-FNTA_SPIDR_chr8_48353104_ENST00000518074_FNTA_chr8_42938261_ENST00000342116_length(amino acids)=305AA_BP=
MAQSLTAEEKTITEKHLELCPRPKQETTTSKSTSGLTDITWSSSGSDLSDEDKTLSQLQRDELQFIDWEIDSDRAEASDCDEFEDDEGAV
EISDCASCASNQSLTSDEKLSELPKPSSIEILEYSSDSEKEDDLENVLLIDSESPHKYHVQFASDARQIMERLIDPRTKSTETILHTPQK
PTAKFPRTPENSAKKKLLRGGLAERLNGLQNRERSAISLWRHQCISYQKTLSGRKSGVLTVKILELHEECAMQVAMCEQLLGSPATSSSQ

--------------------------------------------------------------
>85789_85789_5_SPIDR-FNTA_SPIDR_chr8_48353104_ENST00000541342_FNTA_chr8_42938261_ENST00000302279_length(transcript)=1897nt_BP=1033nt
GAGATGCCCCGCGGCAGCCGCGCTCGGGGCTCTAAGAGAAAAAGGAGTTGGAATACAGAATGCCCATCCTTTCCAGGAGAAAGACCACTG
CAGGTCAGAAGAGCAGGTCTCAGGACAGCAGGGGCAGCTGCCTCTCTCTCTGAAGCATGGCTCAGGTGTGGAGAAGGGTTTCAGAACACT
TCTGGGAATCCGAAACCACCACATCTAAAAGCACCAGTGGGCTTACAGACATAACATGGAGCTCCAGTGGAAGTGATTTGTCGGATGAAG
ATAAGACACTTTCTCAGTTACAGAGAGATGAATTACAGTTTATCGACTGGGAGATTGACAGTGACAGGGCAGAGGCTAGTGACTGTGATG
AATTTGAAGATGACGAGGGTGCTGTGGAAATCTCAGACTGTGCTTCTTGTGCAAGTAATCAGTCTTTGACAAGTGATGAGAAGCTGTCGG
AGCTTCCCAAGCCAAGTTCTATAGAAATTTTAGAGTATTCATCAGATAGTGAAAAAGAAGATGATTTGGAAAATGTCCTACTCATTGATT
CAGAATCCCCTCACAAATACCACGTGCAGTTTGCATCGGATGCAAGACAGATTATGGAGAGACTGATAGATCCAAGGACAAAATCAACAG
AGACCATTTTGCATACACCTCAGAAACCCACAGCTAAGTTTCCCAGGACTCCAGAAAATTCAGCAAAGAAGAAGCTTTTAAGAGGTGGAC
TAGCAGAAAGACTAAATGGACTGCAGAATCGAGAGAGATCTGCTATTTCTTTGTGGAGACATCAATGTATTTCTTACCAAAAGACACTTT
CAGGTAGAAAATCTGGTGTATTAACTGTGAAAATTTTAGAGCTGCATGAGGAATGTGCCATGCAAGTTGCCATGTGTGAGCAGTTATTGG
GGTCACCAGCCACCAGCTCCTCCCAAAGTGTGGCTCCCAGGCCTGGAGCTGGCCTGAAAGTTCTCTTCACCAAGGAGACTGCAGGCTACC
TCAGGGGCCGTCCCCAGGACACTGTCCGGATCTTCCCTCCCTGATACACTCTGGAAATGATTAAACTAGTACCACATAATGAAAGTGCAT
GGAACTATTTGAAAGGGATTTTGCAGGATCGTGGTCTTTCCAAATATCCTAATCTGTTAAATCAATTACTTGATTTACAACCAAGTCATA
GTTCCCCCTACCTAATTGCCTTTCTTGTGGATATCTATGAAGACATGCTAGAAAATCAGTGTGACAATAAGGAAGACATTCTTAATAAAG
CATTAGAGTTATGTGAAATCCTAGCTAAAGAAAAGGACACTATAAGAAAGGAATATTGGAGATACATTGGAAGATCCCTTCAAAGCAAAC
ACAGCACAGAAAATGACTCACCAACAAATGTACAGCAATAACACCATCCAGAAGAACTTGATGGAATGCTTTTATTTTTTATTAAGGGAC
CCTGCAGGAGTTTCACACGAGAGTGGTCCTTCCCTTTGCCTGTGGTGTAAAAGTGCATCACACAGGTATTGCTTTTTAACAAGAACTGAT
GCTCCTTGGGTGCTGCTGCTACTCAGACTAGCTCTAAGTAATGTGATTCTTCTAAAGCAAAGTCATTGGATGGGAGGAGGAAGAAAAAGT
CCCATAAAGGAACTTTTGTAGTCTTATCAACATATAATCTAATCCCTTAGCATCAGCTCCTCCCTCAGTGGTACATGCGTCAAGATTTGT
AGCAGTAATAACTGCAGGTCACTTGTATGTAATGGATGTGAGGTAGCCGAAGTTTGGTTCAGTAAGCAGGGAATACAGTCGTTCCATCAG
AGCTGGTCTGCACACTCACATTATCTTGCTATCACTGTAACCAACTAATGCCAAAAGAACGGTTTTGTAATAAAATTATAGCTGTATCTA

>85789_85789_5_SPIDR-FNTA_SPIDR_chr8_48353104_ENST00000541342_FNTA_chr8_42938261_ENST00000302279_length(amino acids)=295AA_BP=
MAQVWRRVSEHFWESETTTSKSTSGLTDITWSSSGSDLSDEDKTLSQLQRDELQFIDWEIDSDRAEASDCDEFEDDEGAVEISDCASCAS
NQSLTSDEKLSELPKPSSIEILEYSSDSEKEDDLENVLLIDSESPHKYHVQFASDARQIMERLIDPRTKSTETILHTPQKPTAKFPRTPE
NSAKKKLLRGGLAERLNGLQNRERSAISLWRHQCISYQKTLSGRKSGVLTVKILELHEECAMQVAMCEQLLGSPATSSSQSVAPRPGAGL

--------------------------------------------------------------
>85789_85789_6_SPIDR-FNTA_SPIDR_chr8_48353104_ENST00000541342_FNTA_chr8_42938261_ENST00000342116_length(transcript)=1889nt_BP=1033nt
GAGATGCCCCGCGGCAGCCGCGCTCGGGGCTCTAAGAGAAAAAGGAGTTGGAATACAGAATGCCCATCCTTTCCAGGAGAAAGACCACTG
CAGGTCAGAAGAGCAGGTCTCAGGACAGCAGGGGCAGCTGCCTCTCTCTCTGAAGCATGGCTCAGGTGTGGAGAAGGGTTTCAGAACACT
TCTGGGAATCCGAAACCACCACATCTAAAAGCACCAGTGGGCTTACAGACATAACATGGAGCTCCAGTGGAAGTGATTTGTCGGATGAAG
ATAAGACACTTTCTCAGTTACAGAGAGATGAATTACAGTTTATCGACTGGGAGATTGACAGTGACAGGGCAGAGGCTAGTGACTGTGATG
AATTTGAAGATGACGAGGGTGCTGTGGAAATCTCAGACTGTGCTTCTTGTGCAAGTAATCAGTCTTTGACAAGTGATGAGAAGCTGTCGG
AGCTTCCCAAGCCAAGTTCTATAGAAATTTTAGAGTATTCATCAGATAGTGAAAAAGAAGATGATTTGGAAAATGTCCTACTCATTGATT
CAGAATCCCCTCACAAATACCACGTGCAGTTTGCATCGGATGCAAGACAGATTATGGAGAGACTGATAGATCCAAGGACAAAATCAACAG
AGACCATTTTGCATACACCTCAGAAACCCACAGCTAAGTTTCCCAGGACTCCAGAAAATTCAGCAAAGAAGAAGCTTTTAAGAGGTGGAC
TAGCAGAAAGACTAAATGGACTGCAGAATCGAGAGAGATCTGCTATTTCTTTGTGGAGACATCAATGTATTTCTTACCAAAAGACACTTT
CAGGTAGAAAATCTGGTGTATTAACTGTGAAAATTTTAGAGCTGCATGAGGAATGTGCCATGCAAGTTGCCATGTGTGAGCAGTTATTGG
GGTCACCAGCCACCAGCTCCTCCCAAAGTGTGGCTCCCAGGCCTGGAGCTGGCCTGAAAGTTCTCTTCACCAAGGAGACTGCAGGCTACC
TCAGGGGCCGTCCCCAGGACACTGTCCGGATCTTCCCTCCCTGATACACTCTGGAAATGATTAAACTAGTACCACATAATGAAAGTGCAT
GGAACTATTTGAAAGGGATTTTGCAGGATCGTGGTCTTTCCAAATATCCTAATCTGTTAAATCAATTACTTGATTTACAACCAAGTCATA
GTTCCCCCTACCTAATTGCCTTTCTTGTGGATATCTATGAAGACATGCTAGAAAATCAGTGTGACAATAAGGAAGACATTCTTAATAAAG
CATTAGAGTTATGTGAAATCCTAGCTAAAGAAAAGGACACTATAAGAAAGGAATATTGGAGATACATTGGAAGATCCCTTCAAAGCAAAC
ACAGCACAGAAAATGACTCACCAACAAATGTACAGCAATAACACCATCCAGAAGAACTTGATGGAATGCTTTTATTTTTTATTAAGGGAC
CCTGCAGGAGTTTCACACGAGAGTGGTCCTTCCCTTTGCCTGTGGTGTAAAAGTGCATCACACAGGTATTGCTTTTTAACAAGAACTGAT
GCTCCTTGGGTGCTGCTGCTACTCAGACTAGCTCTAAGTAATGTGATTCTTCTAAAGCAAAGTCATTGGATGGGAGGAGGAAGAAAAAGT
CCCATAAAGGAACTTTTGTAGTCTTATCAACATATAATCTAATCCCTTAGCATCAGCTCCTCCCTCAGTGGTACATGCGTCAAGATTTGT
AGCAGTAATAACTGCAGGTCACTTGTATGTAATGGATGTGAGGTAGCCGAAGTTTGGTTCAGTAAGCAGGGAATACAGTCGTTCCATCAG

>85789_85789_6_SPIDR-FNTA_SPIDR_chr8_48353104_ENST00000541342_FNTA_chr8_42938261_ENST00000342116_length(amino acids)=295AA_BP=
MAQVWRRVSEHFWESETTTSKSTSGLTDITWSSSGSDLSDEDKTLSQLQRDELQFIDWEIDSDRAEASDCDEFEDDEGAVEISDCASCAS
NQSLTSDEKLSELPKPSSIEILEYSSDSEKEDDLENVLLIDSESPHKYHVQFASDARQIMERLIDPRTKSTETILHTPQKPTAKFPRTPE
NSAKKKLLRGGLAERLNGLQNRERSAISLWRHQCISYQKTLSGRKSGVLTVKILELHEECAMQVAMCEQLLGSPATSSSQSVAPRPGAGL

--------------------------------------------------------------

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Fusion Gene PPI Analysis for SPIDR-FNTA


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for SPIDR-FNTA


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for SPIDR-FNTA


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource