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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:AXL-ZNF565 (FusionGDB2 ID:8583)

Fusion Gene Summary for AXL-ZNF565

check button Fusion gene summary
Fusion gene informationFusion gene name: AXL-ZNF565
Fusion gene ID: 8583
HgeneTgene
Gene symbol

AXL

ZNF565

Gene ID

558

147929

Gene nameAXL receptor tyrosine kinasezinc finger protein 565
SynonymsARK|JTK11|Tyro7|UFO-
Cytomap

19q13.2

19q13.12

Type of geneprotein-codingprotein-coding
Descriptiontyrosine-protein kinase receptor UFOAXL oncogeneAXL transforming sequence/genezinc finger protein 565
Modification date2020032720200313
UniProtAcc

P30530

.
Ensembl transtripts involved in fusion geneENST00000301178, ENST00000359092, 
ENST00000593513, ENST00000594880, 
ENST00000304116, ENST00000355114, 
ENST00000392173, 
Fusion gene scores* DoF score8 X 7 X 5=2808 X 4 X 5=160
# samples 88
** MAII scorelog2(8/280*10)=-1.8073549220576
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(8/160*10)=-1
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: AXL [Title/Abstract] AND ZNF565 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointAXL(41762516)-ZNF565(36686058), # samples:3
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneAXL

GO:0001961

positive regulation of cytokine-mediated signaling pathway

18840707

HgeneAXL

GO:0006909

phagocytosis

21501828

HgeneAXL

GO:0032689

negative regulation of interferon-gamma production

18840707

HgeneAXL

GO:0032825

positive regulation of natural killer cell differentiation

18840707

HgeneAXL

GO:0035457

cellular response to interferon-alpha

19657094

HgeneAXL

GO:0071222

cellular response to lipopolysaccharide

19657094

HgeneAXL

GO:2000669

negative regulation of dendritic cell apoptotic process

19657094


check buttonFusion gene breakpoints across AXL (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across ZNF565 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4OVTCGA-25-1877-01AAXLchr19

41762516

-ZNF565chr19

36686058

-
ChimerDB4OVTCGA-25-1877-01AAXLchr19

41762516

+ZNF565chr19

36686058

-


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Fusion Gene ORF analysis for AXL-ZNF565

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
In-frameENST00000301178ENST00000304116AXLchr19

41762516

+ZNF565chr19

36686058

-
In-frameENST00000301178ENST00000355114AXLchr19

41762516

+ZNF565chr19

36686058

-
In-frameENST00000301178ENST00000392173AXLchr19

41762516

+ZNF565chr19

36686058

-
In-frameENST00000359092ENST00000304116AXLchr19

41762516

+ZNF565chr19

36686058

-
In-frameENST00000359092ENST00000355114AXLchr19

41762516

+ZNF565chr19

36686058

-
In-frameENST00000359092ENST00000392173AXLchr19

41762516

+ZNF565chr19

36686058

-
In-frameENST00000593513ENST00000304116AXLchr19

41762516

+ZNF565chr19

36686058

-
In-frameENST00000593513ENST00000355114AXLchr19

41762516

+ZNF565chr19

36686058

-
In-frameENST00000593513ENST00000392173AXLchr19

41762516

+ZNF565chr19

36686058

-
intron-3CDSENST00000594880ENST00000304116AXLchr19

41762516

+ZNF565chr19

36686058

-
intron-3CDSENST00000594880ENST00000355114AXLchr19

41762516

+ZNF565chr19

36686058

-
intron-3CDSENST00000594880ENST00000392173AXLchr19

41762516

+ZNF565chr19

36686058

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000301178AXLchr1941762516+ENST00000304116ZNF565chr1936686058-4057238618138761231
ENST00000301178AXLchr1941762516+ENST00000392173ZNF565chr1936686058-4049238618138761231
ENST00000301178AXLchr1941762516+ENST00000355114ZNF565chr1936686058-4049238618138761231
ENST00000359092AXLchr1941762516+ENST00000304116ZNF565chr1936686058-3998232714938171222
ENST00000359092AXLchr1941762516+ENST00000392173ZNF565chr1936686058-3990232714938171222
ENST00000359092AXLchr1941762516+ENST00000355114ZNF565chr1936686058-3990232714938171222
ENST00000593513AXLchr1941762516+ENST00000304116ZNF565chr1936686058-3439176816032581032
ENST00000593513AXLchr1941762516+ENST00000392173ZNF565chr1936686058-3431176816032581032
ENST00000593513AXLchr1941762516+ENST00000355114ZNF565chr1936686058-3431176816032581032

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000301178ENST00000304116AXLchr1941762516+ZNF565chr1936686058-0.0018833980.9981166
ENST00000301178ENST00000392173AXLchr1941762516+ZNF565chr1936686058-0.0018791860.99812084
ENST00000301178ENST00000355114AXLchr1941762516+ZNF565chr1936686058-0.0018791860.99812084
ENST00000359092ENST00000304116AXLchr1941762516+ZNF565chr1936686058-0.0022678480.99773216
ENST00000359092ENST00000392173AXLchr1941762516+ZNF565chr1936686058-0.0022782680.99772173
ENST00000359092ENST00000355114AXLchr1941762516+ZNF565chr1936686058-0.0022782680.99772173
ENST00000593513ENST00000304116AXLchr1941762516+ZNF565chr1936686058-0.0019080660.9980919
ENST00000593513ENST00000392173AXLchr1941762516+ZNF565chr1936686058-0.0019181330.9980819
ENST00000593513ENST00000355114AXLchr1941762516+ZNF565chr1936686058-0.0019181330.9980819

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Fusion Genomic Features for AXL-ZNF565


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for AXL-ZNF565


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr19:41762516/chr19:36686058)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
AXL

P30530

.
FUNCTION: Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding growth factor GAS6 and which is thus regulating many physiological processes including cell survival, cell proliferation, migration and differentiation. Ligand binding at the cell surface induces dimerization and autophosphorylation of AXL. Following activation by ligand, AXL binds and induces tyrosine phosphorylation of PI3-kinase subunits PIK3R1, PIK3R2 and PIK3R3; but also GRB2, PLCG1, LCK and PTPN11. Other downstream substrate candidates for AXL are CBL, NCK2, SOCS1 and TNS2. Recruitment of GRB2 and phosphatidylinositol 3 kinase regulatory subunits by AXL leads to the downstream activation of the AKT kinase. GAS6/AXL signaling plays a role in various processes such as endothelial cell survival during acidification by preventing apoptosis, optimal cytokine signaling during human natural killer cell development, hepatic regeneration, gonadotropin-releasing hormone neuron survival and migration, platelet activation, or regulation of thrombotic responses. Plays also an important role in inhibition of Toll-like receptors (TLRs)-mediated innate immune response. {ECO:0000269|PubMed:10403904, ECO:0000269|PubMed:11484958, ECO:0000269|PubMed:12364394, ECO:0000269|PubMed:12490074, ECO:0000269|PubMed:15507525, ECO:0000269|PubMed:15733062, ECO:0000269|PubMed:1656220, ECO:0000269|PubMed:18840707}.; FUNCTION: (Microbial infection) Acts as a receptor for lassa virus and lymphocytic choriomeningitis virus, possibly through GAS6 binding to phosphatidyl-serine at the surface of virion envelope. {ECO:0000269|PubMed:17005688, ECO:0000269|PubMed:21501828, ECO:0000269|PubMed:22156524, ECO:0000269|PubMed:25277499}.; FUNCTION: (Microbial infection) Acts as a receptor for Ebolavirus, possibly through GAS6 binding to phosphatidyl-serine at the surface of virion envelope. {ECO:0000269|PubMed:22673088}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneAXLchr19:41762516chr19:36686058ENST00000301178+1820139_222732895.0DomainNote=Ig-like C2-type 2
HgeneAXLchr19:41762516chr19:36686058ENST00000301178+1820227_331732895.0DomainFibronectin type-III 1
HgeneAXLchr19:41762516chr19:36686058ENST00000301178+182027_128732895.0DomainNote=Ig-like C2-type 1
HgeneAXLchr19:41762516chr19:36686058ENST00000301178+1820336_428732895.0DomainFibronectin type-III 2
HgeneAXLchr19:41762516chr19:36686058ENST00000359092+1719139_222723886.0DomainNote=Ig-like C2-type 2
HgeneAXLchr19:41762516chr19:36686058ENST00000359092+1719227_331723886.0DomainFibronectin type-III 1
HgeneAXLchr19:41762516chr19:36686058ENST00000359092+171927_128723886.0DomainNote=Ig-like C2-type 1
HgeneAXLchr19:41762516chr19:36686058ENST00000359092+1719336_428723886.0DomainFibronectin type-III 2
HgeneAXLchr19:41762516chr19:36686058ENST00000301178+1820542_550732895.0Nucleotide bindingATP
HgeneAXLchr19:41762516chr19:36686058ENST00000359092+1719542_550723886.0Nucleotide bindingATP
HgeneAXLchr19:41762516chr19:36686058ENST00000301178+182026_451732895.0Topological domainExtracellular
HgeneAXLchr19:41762516chr19:36686058ENST00000359092+171926_451723886.0Topological domainExtracellular
HgeneAXLchr19:41762516chr19:36686058ENST00000301178+1820452_472732895.0TransmembraneHelical
HgeneAXLchr19:41762516chr19:36686058ENST00000359092+1719452_472723886.0TransmembraneHelical
TgeneZNF565chr19:41762516chr19:36686058ENST000003041161546_1173500.0DomainKRAB
TgeneZNF565chr19:41762516chr19:36686058ENST000003921731546_1173500.0DomainKRAB
TgeneZNF565chr19:41762516chr19:36686058ENST0000030411615207_2293500.0Zinc fingerC2H2-type 1
TgeneZNF565chr19:41762516chr19:36686058ENST0000030411615235_2573500.0Zinc fingerC2H2-type 2
TgeneZNF565chr19:41762516chr19:36686058ENST0000030411615263_2853500.0Zinc fingerC2H2-type 3
TgeneZNF565chr19:41762516chr19:36686058ENST0000030411615291_3133500.0Zinc fingerC2H2-type 4
TgeneZNF565chr19:41762516chr19:36686058ENST0000030411615319_3413500.0Zinc fingerC2H2-type 5
TgeneZNF565chr19:41762516chr19:36686058ENST0000030411615347_3693500.0Zinc fingerC2H2-type 6
TgeneZNF565chr19:41762516chr19:36686058ENST0000030411615375_3973500.0Zinc fingerC2H2-type 7
TgeneZNF565chr19:41762516chr19:36686058ENST0000030411615403_4253500.0Zinc fingerC2H2-type 8
TgeneZNF565chr19:41762516chr19:36686058ENST0000030411615431_4533500.0Zinc fingerC2H2-type 9
TgeneZNF565chr19:41762516chr19:36686058ENST0000030411615459_4813500.0Zinc fingerC2H2-type 10
TgeneZNF565chr19:41762516chr19:36686058ENST0000030411615487_5093500.0Zinc fingerC2H2-type 11
TgeneZNF565chr19:41762516chr19:36686058ENST0000030411615515_5373500.0Zinc fingerC2H2-type 12
TgeneZNF565chr19:41762516chr19:36686058ENST0000039217315207_2293500.0Zinc fingerC2H2-type 1
TgeneZNF565chr19:41762516chr19:36686058ENST0000039217315235_2573500.0Zinc fingerC2H2-type 2
TgeneZNF565chr19:41762516chr19:36686058ENST0000039217315263_2853500.0Zinc fingerC2H2-type 3
TgeneZNF565chr19:41762516chr19:36686058ENST0000039217315291_3133500.0Zinc fingerC2H2-type 4
TgeneZNF565chr19:41762516chr19:36686058ENST0000039217315319_3413500.0Zinc fingerC2H2-type 5
TgeneZNF565chr19:41762516chr19:36686058ENST0000039217315347_3693500.0Zinc fingerC2H2-type 6
TgeneZNF565chr19:41762516chr19:36686058ENST0000039217315375_3973500.0Zinc fingerC2H2-type 7
TgeneZNF565chr19:41762516chr19:36686058ENST0000039217315403_4253500.0Zinc fingerC2H2-type 8
TgeneZNF565chr19:41762516chr19:36686058ENST0000039217315431_4533500.0Zinc fingerC2H2-type 9
TgeneZNF565chr19:41762516chr19:36686058ENST0000039217315459_4813500.0Zinc fingerC2H2-type 10
TgeneZNF565chr19:41762516chr19:36686058ENST0000039217315487_5093500.0Zinc fingerC2H2-type 11
TgeneZNF565chr19:41762516chr19:36686058ENST0000039217315515_5373500.0Zinc fingerC2H2-type 12

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneAXLchr19:41762516chr19:36686058ENST00000301178+1820536_807732895.0DomainProtein kinase
HgeneAXLchr19:41762516chr19:36686058ENST00000359092+1719536_807723886.0DomainProtein kinase
HgeneAXLchr19:41762516chr19:36686058ENST00000301178+1820473_894732895.0Topological domainCytoplasmic
HgeneAXLchr19:41762516chr19:36686058ENST00000359092+1719473_894723886.0Topological domainCytoplasmic


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Fusion Gene Sequence for AXL-ZNF565


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>8583_8583_1_AXL-ZNF565_AXL_chr19_41762516_ENST00000301178_ZNF565_chr19_36686058_ENST00000304116_length(transcript)=4057nt_BP=2386nt
GGGAAGGAGGCAGGGGTGCTGAGAAGGCGGCTGCTGGGCAGAGCCGGTGGCAAGGGCCTCCCCTGCCGCTGTGCCAGGCAGGCAGTGCCA
AATCCGGGGAGCCTGGAGCTGGGGGGAGGGCCGGGGACAGCCCGGCCCTGCCCCCTCCCCCGCTGGGAGCCCAACAACTTCTGAGGAAAG
TTTGGCACCCATGGCGTGGCGGTGCCCCAGGATGGGCAGGGTCCCGCTGGCCTGGTGCTTGGCGCTGTGCGGCTGGGCGTGCATGGCCCC
CAGGGGCACGCAGGCTGAAGAAAGTCCCTTCGTGGGCAACCCAGGGAATATCACAGGTGCCCGGGGACTCACGGGCACCCTTCGGTGTCA
GCTCCAGGTTCAGGGAGAGCCCCCCGAGGTACATTGGCTTCGGGATGGACAGATCCTGGAGCTCGCGGACAGCACCCAGACCCAGGTGCC
CCTGGGTGAGGATGAACAGGATGACTGGATAGTGGTCAGCCAGCTCAGAATCACCTCCCTGCAGCTTTCCGACACGGGACAGTACCAGTG
TTTGGTGTTTCTGGGACATCAGACCTTCGTGTCCCAGCCTGGCTATGTTGGGCTGGAGGGCTTGCCTTACTTCCTGGAGGAGCCCGAAGA
CAGGACTGTGGCCGCCAACACCCCCTTCAACCTGAGCTGCCAAGCTCAGGGACCCCCAGAGCCCGTGGACCTACTCTGGCTCCAGGATGC
TGTCCCCCTGGCCACGGCTCCAGGTCACGGCCCCCAGCGCAGCCTGCATGTTCCAGGGCTGAACAAGACATCCTCTTTCTCCTGCGAAGC
CCATAACGCCAAGGGGGTCACCACATCCCGCACAGCCACCATCACAGTGCTCCCCCAGCAGCCCCGTAACCTCCACCTGGTCTCCCGCCA
ACCCACGGAGCTGGAGGTGGCTTGGACTCCAGGCCTGAGCGGCATCTACCCCCTGACCCACTGCACCCTGCAGGCTGTGCTGTCAAACGA
TGGGATGGGCATCCAGGCGGGAGAACCAGACCCCCCAGAGGAGCCCCTCACCTCGCAAGCATCCGTGCCCCCCCATCAGCTTCGGCTAGG
CAGCCTCCATCCTCACACCCCTTATCACATCCGCGTGGCATGCACCAGCAGCCAGGGCCCCTCATCCTGGACCCACTGGCTTCCTGTGGA
GACGCCGGAGGGAGTGCCCCTGGGCCCCCCTGAGAACATTAGTGCTACGCGGAATGGGAGCCAGGCCTTCGTGCATTGGCAAGAGCCCCG
GGCGCCCCTGCAGGGTACCCTGTTAGGGTACCGGCTGGCGTATCAAGGCCAGGACACCCCAGAGGTGCTAATGGACATAGGGCTAAGGCA
AGAGGTGACCCTGGAGCTGCAGGGGGACGGGTCTGTGTCCAATCTGACAGTGTGTGTGGCAGCCTACACTGCTGCTGGGGATGGACCCTG
GAGCCTCCCAGTACCCCTGGAGGCCTGGCGCCCAGGGCAAGCACAGCCAGTCCACCAGCTGGTGAAGGAACCTTCAACTCCTGCCTTCTC
GTGGCCCTGGTGGTATGTACTGCTAGGAGCAGTCGTGGCCGCTGCCTGTGTCCTCATCTTGGCTCTCTTCCTTGTCCACCGGCGAAAGAA
GGAGACCCGTTATGGAGAAGTGTTTGAACCAACAGTGGAAAGAGGTGAACTGGTAGTCAGGTACCGCGTGCGCAAGTCCTACAGTCGTCG
GACCACTGAAGCTACCTTGAACAGCCTGGGCATCAGTGAAGAGCTGAAGGAGAAGCTGCGGGATGTGATGGTGGACCGGCACAAGGTGGC
CCTGGGGAAGACTCTGGGAGAGGGAGAGTTTGGAGCTGTGATGGAAGGCCAGCTCAACCAGGACGACTCCATCCTCAAGGTGGCTGTGAA
GACGATGAAGATTGCCATCTGCACGAGGTCAGAGCTGGAGGATTTCCTGAGTGAAGCGGTCTGCATGAAGGAATTTGACCATCCCAACGT
CATGAGGCTCATCGGTGTCTGTTTCCAGGGTTCTGAACGAGAGAGCTTCCCAGCACCTGTGGTCATCTTACCTTTCATGAAACATGGAGA
CCTACACAGCTTCCTCCTCTATTCCCGGCTCGGGGACCAGCCAGTGTACCTGCCCACTCAGATGCTAGTGAAGTTCATGGCAGACATCGC
CAGTGGCATGGAGTATCTGAGTACCAAGAGATTCATACACCGGGACCTGGCGGCCAGGAACTGCATGCTGAATGAGAACATGTCCGTGTG
TGTGGCGGACTTCGGGCTCTCCAAGAAGATCTACAATGGGGACTACTACCGCCAGGGACGTATCGCCAAGATGCCAGTCAAGTGGATTGC
CATTGAGAGTCTAGCTGACCGTGTCTACACCAGCAAGAGCGATGTGGGACTGGTGACATTCAGGGACGTGGCCATAGAGTTCTCTCTGGA
AGAATGGAAGTGCCTGGAACCTGCTCAGAGGGACTTGTACAGGGAGGTGACTCTGGAGAACTTTGGTCACTTGGCCTCACTAGGACTCTC
CATTTCTAAGCCTGATGTCGTCTCCTTATTGGAGCAAGGGAAAGAGCCCTGGATGATTGCAAATGATGTGACAGGACCATGGTGCCCAGA
CTTGGAGTCCAGGTGTGAGAAATTTCTACAAAAAGACATTTTTGAAATCGGGGCATTCAACTGGGAGATAATGGAAAGCCTTAAATGCAG
TGACCTGGAGGGCTCCGATTTTAGAGCTGACTGGGAATGCGAAGGCCAGTTTGAGAGACAAGTCAATGAAGAGTGCTATTTTAAGCAAGT
GAACGTCACCTATGGACATATGCCCGTGTTCCAGCATCACACGTCTCACACTGTACGTCAGAGCAGGGAGACTGGTGAGAAACTGATGGA
ATGTCATGAATGTGGGAAAGCATTTAGCCGTGGCTCACACCTTATTCAACATCAGAAAATTCACACTGGTGAAAAACCCTTTGGATGTAA
GGAATGTGGGAAGGCCTTCAGCCGTGCCTCACACCTTGTTCAGCATCAGAGAATTCACACGGGTGAGAAACCTTATGACTGTAAGGACTG
TGGGAAGGCCTTTGGTCGTACATCAGAACTTATTCTACATCAGAGACTTCATACTGGTGTCAAACCTTATGAATGTAAAGAATGTGGGAA
GACCTTTAGGCAGCATTCACAGCTGATTCTGCATCAAAGAACTCACACAGGCGAGAAACCCTACGTATGTAAAGACTGTGGCAAGGCTTT
CATTCGTGGCTCCCAACTCACTGTGCATCGGAGAATCCACACAGGGGCCAGACCCTATGAGTGTAAAGAATGCGGGAAAGCCTTTAGACA
GCACTCACAGCTGACTGTACACCAGCGAATCCACACTGGTGAGAAACCCTACGAGTGTAAGGAATGCGGAAAGGGCTTTATTCACAGCTC
AGAAGTTACTCGACATCAAAGAATTCATTCTGGGGAGAAACCCTATGAGTGTAAGGAATGTGGGAAGGCCTTCAGACAGCACGCACAGCT
CACACGACATCAGAGAGTCCATACTGGCGACAGACCCTATGAATGTAAGGACTGCGGGAAGGCATTTAGTCGTAGCTCATACCTCATTCA
ACATCAAAGAATTCATACAGGTGACAAACCCTACGAATGTAAGGAATGTGGGAAGGCCTTTATTCGTGTTTCACAACTGACTCATCATCA
GCGAATTCACACTTGTGAGAAACCCTATGAATGCAGGGAGTGTGGAATGGCCTTTATTCGTAGTTCACAACTTACCGAACATCAGAGAAT
TCATCCTGGTATCAAACCTTACGAATGTAGAGAGTGTGGGCAGGCATTTATTCTTGGCTCACAACTCATTGAACACTACAGAATTCATAC
TGGTTAGAAAGCCTTGAGTGTAAGGGATAAAGATAAGCCTTTATGTGGAGTTCACATCTGGCTCAGTACTAGGTAATTTTTAATGTAGTG
TAATTAATGTCAGAAAACACCTGTCACTTCCATCATAGAACATCAGAAAACTCACACCCAAAGAAAATTAAATAAATGTGGGAATTCTTT

>8583_8583_1_AXL-ZNF565_AXL_chr19_41762516_ENST00000301178_ZNF565_chr19_36686058_ENST00000304116_length(amino acids)=1231AA_BP=777
MAPMAWRCPRMGRVPLAWCLALCGWACMAPRGTQAEESPFVGNPGNITGARGLTGTLRCQLQVQGEPPEVHWLRDGQILELADSTQTQVP
LGEDEQDDWIVVSQLRITSLQLSDTGQYQCLVFLGHQTFVSQPGYVGLEGLPYFLEEPEDRTVAANTPFNLSCQAQGPPEPVDLLWLQDA
VPLATAPGHGPQRSLHVPGLNKTSSFSCEAHNAKGVTTSRTATITVLPQQPRNLHLVSRQPTELEVAWTPGLSGIYPLTHCTLQAVLSND
GMGIQAGEPDPPEEPLTSQASVPPHQLRLGSLHPHTPYHIRVACTSSQGPSSWTHWLPVETPEGVPLGPPENISATRNGSQAFVHWQEPR
APLQGTLLGYRLAYQGQDTPEVLMDIGLRQEVTLELQGDGSVSNLTVCVAAYTAAGDGPWSLPVPLEAWRPGQAQPVHQLVKEPSTPAFS
WPWWYVLLGAVVAAACVLILALFLVHRRKKETRYGEVFEPTVERGELVVRYRVRKSYSRRTTEATLNSLGISEELKEKLRDVMVDRHKVA
LGKTLGEGEFGAVMEGQLNQDDSILKVAVKTMKIAICTRSELEDFLSEAVCMKEFDHPNVMRLIGVCFQGSERESFPAPVVILPFMKHGD
LHSFLLYSRLGDQPVYLPTQMLVKFMADIASGMEYLSTKRFIHRDLAARNCMLNENMSVCVADFGLSKKIYNGDYYRQGRIAKMPVKWIA
IESLADRVYTSKSDVGLVTFRDVAIEFSLEEWKCLEPAQRDLYREVTLENFGHLASLGLSISKPDVVSLLEQGKEPWMIANDVTGPWCPD
LESRCEKFLQKDIFEIGAFNWEIMESLKCSDLEGSDFRADWECEGQFERQVNEECYFKQVNVTYGHMPVFQHHTSHTVRQSRETGEKLME
CHECGKAFSRGSHLIQHQKIHTGEKPFGCKECGKAFSRASHLVQHQRIHTGEKPYDCKDCGKAFGRTSELILHQRLHTGVKPYECKECGK
TFRQHSQLILHQRTHTGEKPYVCKDCGKAFIRGSQLTVHRRIHTGARPYECKECGKAFRQHSQLTVHQRIHTGEKPYECKECGKGFIHSS
EVTRHQRIHSGEKPYECKECGKAFRQHAQLTRHQRVHTGDRPYECKDCGKAFSRSSYLIQHQRIHTGDKPYECKECGKAFIRVSQLTHHQ

--------------------------------------------------------------
>8583_8583_2_AXL-ZNF565_AXL_chr19_41762516_ENST00000301178_ZNF565_chr19_36686058_ENST00000355114_length(transcript)=4049nt_BP=2386nt
GGGAAGGAGGCAGGGGTGCTGAGAAGGCGGCTGCTGGGCAGAGCCGGTGGCAAGGGCCTCCCCTGCCGCTGTGCCAGGCAGGCAGTGCCA
AATCCGGGGAGCCTGGAGCTGGGGGGAGGGCCGGGGACAGCCCGGCCCTGCCCCCTCCCCCGCTGGGAGCCCAACAACTTCTGAGGAAAG
TTTGGCACCCATGGCGTGGCGGTGCCCCAGGATGGGCAGGGTCCCGCTGGCCTGGTGCTTGGCGCTGTGCGGCTGGGCGTGCATGGCCCC
CAGGGGCACGCAGGCTGAAGAAAGTCCCTTCGTGGGCAACCCAGGGAATATCACAGGTGCCCGGGGACTCACGGGCACCCTTCGGTGTCA
GCTCCAGGTTCAGGGAGAGCCCCCCGAGGTACATTGGCTTCGGGATGGACAGATCCTGGAGCTCGCGGACAGCACCCAGACCCAGGTGCC
CCTGGGTGAGGATGAACAGGATGACTGGATAGTGGTCAGCCAGCTCAGAATCACCTCCCTGCAGCTTTCCGACACGGGACAGTACCAGTG
TTTGGTGTTTCTGGGACATCAGACCTTCGTGTCCCAGCCTGGCTATGTTGGGCTGGAGGGCTTGCCTTACTTCCTGGAGGAGCCCGAAGA
CAGGACTGTGGCCGCCAACACCCCCTTCAACCTGAGCTGCCAAGCTCAGGGACCCCCAGAGCCCGTGGACCTACTCTGGCTCCAGGATGC
TGTCCCCCTGGCCACGGCTCCAGGTCACGGCCCCCAGCGCAGCCTGCATGTTCCAGGGCTGAACAAGACATCCTCTTTCTCCTGCGAAGC
CCATAACGCCAAGGGGGTCACCACATCCCGCACAGCCACCATCACAGTGCTCCCCCAGCAGCCCCGTAACCTCCACCTGGTCTCCCGCCA
ACCCACGGAGCTGGAGGTGGCTTGGACTCCAGGCCTGAGCGGCATCTACCCCCTGACCCACTGCACCCTGCAGGCTGTGCTGTCAAACGA
TGGGATGGGCATCCAGGCGGGAGAACCAGACCCCCCAGAGGAGCCCCTCACCTCGCAAGCATCCGTGCCCCCCCATCAGCTTCGGCTAGG
CAGCCTCCATCCTCACACCCCTTATCACATCCGCGTGGCATGCACCAGCAGCCAGGGCCCCTCATCCTGGACCCACTGGCTTCCTGTGGA
GACGCCGGAGGGAGTGCCCCTGGGCCCCCCTGAGAACATTAGTGCTACGCGGAATGGGAGCCAGGCCTTCGTGCATTGGCAAGAGCCCCG
GGCGCCCCTGCAGGGTACCCTGTTAGGGTACCGGCTGGCGTATCAAGGCCAGGACACCCCAGAGGTGCTAATGGACATAGGGCTAAGGCA
AGAGGTGACCCTGGAGCTGCAGGGGGACGGGTCTGTGTCCAATCTGACAGTGTGTGTGGCAGCCTACACTGCTGCTGGGGATGGACCCTG
GAGCCTCCCAGTACCCCTGGAGGCCTGGCGCCCAGGGCAAGCACAGCCAGTCCACCAGCTGGTGAAGGAACCTTCAACTCCTGCCTTCTC
GTGGCCCTGGTGGTATGTACTGCTAGGAGCAGTCGTGGCCGCTGCCTGTGTCCTCATCTTGGCTCTCTTCCTTGTCCACCGGCGAAAGAA
GGAGACCCGTTATGGAGAAGTGTTTGAACCAACAGTGGAAAGAGGTGAACTGGTAGTCAGGTACCGCGTGCGCAAGTCCTACAGTCGTCG
GACCACTGAAGCTACCTTGAACAGCCTGGGCATCAGTGAAGAGCTGAAGGAGAAGCTGCGGGATGTGATGGTGGACCGGCACAAGGTGGC
CCTGGGGAAGACTCTGGGAGAGGGAGAGTTTGGAGCTGTGATGGAAGGCCAGCTCAACCAGGACGACTCCATCCTCAAGGTGGCTGTGAA
GACGATGAAGATTGCCATCTGCACGAGGTCAGAGCTGGAGGATTTCCTGAGTGAAGCGGTCTGCATGAAGGAATTTGACCATCCCAACGT
CATGAGGCTCATCGGTGTCTGTTTCCAGGGTTCTGAACGAGAGAGCTTCCCAGCACCTGTGGTCATCTTACCTTTCATGAAACATGGAGA
CCTACACAGCTTCCTCCTCTATTCCCGGCTCGGGGACCAGCCAGTGTACCTGCCCACTCAGATGCTAGTGAAGTTCATGGCAGACATCGC
CAGTGGCATGGAGTATCTGAGTACCAAGAGATTCATACACCGGGACCTGGCGGCCAGGAACTGCATGCTGAATGAGAACATGTCCGTGTG
TGTGGCGGACTTCGGGCTCTCCAAGAAGATCTACAATGGGGACTACTACCGCCAGGGACGTATCGCCAAGATGCCAGTCAAGTGGATTGC
CATTGAGAGTCTAGCTGACCGTGTCTACACCAGCAAGAGCGATGTGGGACTGGTGACATTCAGGGACGTGGCCATAGAGTTCTCTCTGGA
AGAATGGAAGTGCCTGGAACCTGCTCAGAGGGACTTGTACAGGGAGGTGACTCTGGAGAACTTTGGTCACTTGGCCTCACTAGGACTCTC
CATTTCTAAGCCTGATGTCGTCTCCTTATTGGAGCAAGGGAAAGAGCCCTGGATGATTGCAAATGATGTGACAGGACCATGGTGCCCAGA
CTTGGAGTCCAGGTGTGAGAAATTTCTACAAAAAGACATTTTTGAAATCGGGGCATTCAACTGGGAGATAATGGAAAGCCTTAAATGCAG
TGACCTGGAGGGCTCCGATTTTAGAGCTGACTGGGAATGCGAAGGCCAGTTTGAGAGACAAGTCAATGAAGAGTGCTATTTTAAGCAAGT
GAACGTCACCTATGGACATATGCCCGTGTTCCAGCATCACACGTCTCACACTGTACGTCAGAGCAGGGAGACTGGTGAGAAACTGATGGA
ATGTCATGAATGTGGGAAAGCATTTAGCCGTGGCTCACACCTTATTCAACATCAGAAAATTCACACTGGTGAAAAACCCTTTGGATGTAA
GGAATGTGGGAAGGCCTTCAGCCGTGCCTCACACCTTGTTCAGCATCAGAGAATTCACACGGGTGAGAAACCTTATGACTGTAAGGACTG
TGGGAAGGCCTTTGGTCGTACATCAGAACTTATTCTACATCAGAGACTTCATACTGGTGTCAAACCTTATGAATGTAAAGAATGTGGGAA
GACCTTTAGGCAGCATTCACAGCTGATTCTGCATCAAAGAACTCACACAGGCGAGAAACCCTACGTATGTAAAGACTGTGGCAAGGCTTT
CATTCGTGGCTCCCAACTCACTGTGCATCGGAGAATCCACACAGGGGCCAGACCCTATGAGTGTAAAGAATGCGGGAAAGCCTTTAGACA
GCACTCACAGCTGACTGTACACCAGCGAATCCACACTGGTGAGAAACCCTACGAGTGTAAGGAATGCGGAAAGGGCTTTATTCACAGCTC
AGAAGTTACTCGACATCAAAGAATTCATTCTGGGGAGAAACCCTATGAGTGTAAGGAATGTGGGAAGGCCTTCAGACAGCACGCACAGCT
CACACGACATCAGAGAGTCCATACTGGCGACAGACCCTATGAATGTAAGGACTGCGGGAAGGCATTTAGTCGTAGCTCATACCTCATTCA
ACATCAAAGAATTCATACAGGTGACAAACCCTACGAATGTAAGGAATGTGGGAAGGCCTTTATTCGTGTTTCACAACTGACTCATCATCA
GCGAATTCACACTTGTGAGAAACCCTATGAATGCAGGGAGTGTGGAATGGCCTTTATTCGTAGTTCACAACTTACCGAACATCAGAGAAT
TCATCCTGGTATCAAACCTTACGAATGTAGAGAGTGTGGGCAGGCATTTATTCTTGGCTCACAACTCATTGAACACTACAGAATTCATAC
TGGTTAGAAAGCCTTGAGTGTAAGGGATAAAGATAAGCCTTTATGTGGAGTTCACATCTGGCTCAGTACTAGGTAATTTTTAATGTAGTG

>8583_8583_2_AXL-ZNF565_AXL_chr19_41762516_ENST00000301178_ZNF565_chr19_36686058_ENST00000355114_length(amino acids)=1231AA_BP=777
MAPMAWRCPRMGRVPLAWCLALCGWACMAPRGTQAEESPFVGNPGNITGARGLTGTLRCQLQVQGEPPEVHWLRDGQILELADSTQTQVP
LGEDEQDDWIVVSQLRITSLQLSDTGQYQCLVFLGHQTFVSQPGYVGLEGLPYFLEEPEDRTVAANTPFNLSCQAQGPPEPVDLLWLQDA
VPLATAPGHGPQRSLHVPGLNKTSSFSCEAHNAKGVTTSRTATITVLPQQPRNLHLVSRQPTELEVAWTPGLSGIYPLTHCTLQAVLSND
GMGIQAGEPDPPEEPLTSQASVPPHQLRLGSLHPHTPYHIRVACTSSQGPSSWTHWLPVETPEGVPLGPPENISATRNGSQAFVHWQEPR
APLQGTLLGYRLAYQGQDTPEVLMDIGLRQEVTLELQGDGSVSNLTVCVAAYTAAGDGPWSLPVPLEAWRPGQAQPVHQLVKEPSTPAFS
WPWWYVLLGAVVAAACVLILALFLVHRRKKETRYGEVFEPTVERGELVVRYRVRKSYSRRTTEATLNSLGISEELKEKLRDVMVDRHKVA
LGKTLGEGEFGAVMEGQLNQDDSILKVAVKTMKIAICTRSELEDFLSEAVCMKEFDHPNVMRLIGVCFQGSERESFPAPVVILPFMKHGD
LHSFLLYSRLGDQPVYLPTQMLVKFMADIASGMEYLSTKRFIHRDLAARNCMLNENMSVCVADFGLSKKIYNGDYYRQGRIAKMPVKWIA
IESLADRVYTSKSDVGLVTFRDVAIEFSLEEWKCLEPAQRDLYREVTLENFGHLASLGLSISKPDVVSLLEQGKEPWMIANDVTGPWCPD
LESRCEKFLQKDIFEIGAFNWEIMESLKCSDLEGSDFRADWECEGQFERQVNEECYFKQVNVTYGHMPVFQHHTSHTVRQSRETGEKLME
CHECGKAFSRGSHLIQHQKIHTGEKPFGCKECGKAFSRASHLVQHQRIHTGEKPYDCKDCGKAFGRTSELILHQRLHTGVKPYECKECGK
TFRQHSQLILHQRTHTGEKPYVCKDCGKAFIRGSQLTVHRRIHTGARPYECKECGKAFRQHSQLTVHQRIHTGEKPYECKECGKGFIHSS
EVTRHQRIHSGEKPYECKECGKAFRQHAQLTRHQRVHTGDRPYECKDCGKAFSRSSYLIQHQRIHTGDKPYECKECGKAFIRVSQLTHHQ

--------------------------------------------------------------
>8583_8583_3_AXL-ZNF565_AXL_chr19_41762516_ENST00000301178_ZNF565_chr19_36686058_ENST00000392173_length(transcript)=4049nt_BP=2386nt
GGGAAGGAGGCAGGGGTGCTGAGAAGGCGGCTGCTGGGCAGAGCCGGTGGCAAGGGCCTCCCCTGCCGCTGTGCCAGGCAGGCAGTGCCA
AATCCGGGGAGCCTGGAGCTGGGGGGAGGGCCGGGGACAGCCCGGCCCTGCCCCCTCCCCCGCTGGGAGCCCAACAACTTCTGAGGAAAG
TTTGGCACCCATGGCGTGGCGGTGCCCCAGGATGGGCAGGGTCCCGCTGGCCTGGTGCTTGGCGCTGTGCGGCTGGGCGTGCATGGCCCC
CAGGGGCACGCAGGCTGAAGAAAGTCCCTTCGTGGGCAACCCAGGGAATATCACAGGTGCCCGGGGACTCACGGGCACCCTTCGGTGTCA
GCTCCAGGTTCAGGGAGAGCCCCCCGAGGTACATTGGCTTCGGGATGGACAGATCCTGGAGCTCGCGGACAGCACCCAGACCCAGGTGCC
CCTGGGTGAGGATGAACAGGATGACTGGATAGTGGTCAGCCAGCTCAGAATCACCTCCCTGCAGCTTTCCGACACGGGACAGTACCAGTG
TTTGGTGTTTCTGGGACATCAGACCTTCGTGTCCCAGCCTGGCTATGTTGGGCTGGAGGGCTTGCCTTACTTCCTGGAGGAGCCCGAAGA
CAGGACTGTGGCCGCCAACACCCCCTTCAACCTGAGCTGCCAAGCTCAGGGACCCCCAGAGCCCGTGGACCTACTCTGGCTCCAGGATGC
TGTCCCCCTGGCCACGGCTCCAGGTCACGGCCCCCAGCGCAGCCTGCATGTTCCAGGGCTGAACAAGACATCCTCTTTCTCCTGCGAAGC
CCATAACGCCAAGGGGGTCACCACATCCCGCACAGCCACCATCACAGTGCTCCCCCAGCAGCCCCGTAACCTCCACCTGGTCTCCCGCCA
ACCCACGGAGCTGGAGGTGGCTTGGACTCCAGGCCTGAGCGGCATCTACCCCCTGACCCACTGCACCCTGCAGGCTGTGCTGTCAAACGA
TGGGATGGGCATCCAGGCGGGAGAACCAGACCCCCCAGAGGAGCCCCTCACCTCGCAAGCATCCGTGCCCCCCCATCAGCTTCGGCTAGG
CAGCCTCCATCCTCACACCCCTTATCACATCCGCGTGGCATGCACCAGCAGCCAGGGCCCCTCATCCTGGACCCACTGGCTTCCTGTGGA
GACGCCGGAGGGAGTGCCCCTGGGCCCCCCTGAGAACATTAGTGCTACGCGGAATGGGAGCCAGGCCTTCGTGCATTGGCAAGAGCCCCG
GGCGCCCCTGCAGGGTACCCTGTTAGGGTACCGGCTGGCGTATCAAGGCCAGGACACCCCAGAGGTGCTAATGGACATAGGGCTAAGGCA
AGAGGTGACCCTGGAGCTGCAGGGGGACGGGTCTGTGTCCAATCTGACAGTGTGTGTGGCAGCCTACACTGCTGCTGGGGATGGACCCTG
GAGCCTCCCAGTACCCCTGGAGGCCTGGCGCCCAGGGCAAGCACAGCCAGTCCACCAGCTGGTGAAGGAACCTTCAACTCCTGCCTTCTC
GTGGCCCTGGTGGTATGTACTGCTAGGAGCAGTCGTGGCCGCTGCCTGTGTCCTCATCTTGGCTCTCTTCCTTGTCCACCGGCGAAAGAA
GGAGACCCGTTATGGAGAAGTGTTTGAACCAACAGTGGAAAGAGGTGAACTGGTAGTCAGGTACCGCGTGCGCAAGTCCTACAGTCGTCG
GACCACTGAAGCTACCTTGAACAGCCTGGGCATCAGTGAAGAGCTGAAGGAGAAGCTGCGGGATGTGATGGTGGACCGGCACAAGGTGGC
CCTGGGGAAGACTCTGGGAGAGGGAGAGTTTGGAGCTGTGATGGAAGGCCAGCTCAACCAGGACGACTCCATCCTCAAGGTGGCTGTGAA
GACGATGAAGATTGCCATCTGCACGAGGTCAGAGCTGGAGGATTTCCTGAGTGAAGCGGTCTGCATGAAGGAATTTGACCATCCCAACGT
CATGAGGCTCATCGGTGTCTGTTTCCAGGGTTCTGAACGAGAGAGCTTCCCAGCACCTGTGGTCATCTTACCTTTCATGAAACATGGAGA
CCTACACAGCTTCCTCCTCTATTCCCGGCTCGGGGACCAGCCAGTGTACCTGCCCACTCAGATGCTAGTGAAGTTCATGGCAGACATCGC
CAGTGGCATGGAGTATCTGAGTACCAAGAGATTCATACACCGGGACCTGGCGGCCAGGAACTGCATGCTGAATGAGAACATGTCCGTGTG
TGTGGCGGACTTCGGGCTCTCCAAGAAGATCTACAATGGGGACTACTACCGCCAGGGACGTATCGCCAAGATGCCAGTCAAGTGGATTGC
CATTGAGAGTCTAGCTGACCGTGTCTACACCAGCAAGAGCGATGTGGGACTGGTGACATTCAGGGACGTGGCCATAGAGTTCTCTCTGGA
AGAATGGAAGTGCCTGGAACCTGCTCAGAGGGACTTGTACAGGGAGGTGACTCTGGAGAACTTTGGTCACTTGGCCTCACTAGGACTCTC
CATTTCTAAGCCTGATGTCGTCTCCTTATTGGAGCAAGGGAAAGAGCCCTGGATGATTGCAAATGATGTGACAGGACCATGGTGCCCAGA
CTTGGAGTCCAGGTGTGAGAAATTTCTACAAAAAGACATTTTTGAAATCGGGGCATTCAACTGGGAGATAATGGAAAGCCTTAAATGCAG
TGACCTGGAGGGCTCCGATTTTAGAGCTGACTGGGAATGCGAAGGCCAGTTTGAGAGACAAGTCAATGAAGAGTGCTATTTTAAGCAAGT
GAACGTCACCTATGGACATATGCCCGTGTTCCAGCATCACACGTCTCACACTGTACGTCAGAGCAGGGAGACTGGTGAGAAACTGATGGA
ATGTCATGAATGTGGGAAAGCATTTAGCCGTGGCTCACACCTTATTCAACATCAGAAAATTCACACTGGTGAAAAACCCTTTGGATGTAA
GGAATGTGGGAAGGCCTTCAGCCGTGCCTCACACCTTGTTCAGCATCAGAGAATTCACACGGGTGAGAAACCTTATGACTGTAAGGACTG
TGGGAAGGCCTTTGGTCGTACATCAGAACTTATTCTACATCAGAGACTTCATACTGGTGTCAAACCTTATGAATGTAAAGAATGTGGGAA
GACCTTTAGGCAGCATTCACAGCTGATTCTGCATCAAAGAACTCACACAGGCGAGAAACCCTACGTATGTAAAGACTGTGGCAAGGCTTT
CATTCGTGGCTCCCAACTCACTGTGCATCGGAGAATCCACACAGGGGCCAGACCCTATGAGTGTAAAGAATGCGGGAAAGCCTTTAGACA
GCACTCACAGCTGACTGTACACCAGCGAATCCACACTGGTGAGAAACCCTACGAGTGTAAGGAATGCGGAAAGGGCTTTATTCACAGCTC
AGAAGTTACTCGACATCAAAGAATTCATTCTGGGGAGAAACCCTATGAGTGTAAGGAATGTGGGAAGGCCTTCAGACAGCACGCACAGCT
CACACGACATCAGAGAGTCCATACTGGCGACAGACCCTATGAATGTAAGGACTGCGGGAAGGCATTTAGTCGTAGCTCATACCTCATTCA
ACATCAAAGAATTCATACAGGTGACAAACCCTACGAATGTAAGGAATGTGGGAAGGCCTTTATTCGTGTTTCACAACTGACTCATCATCA
GCGAATTCACACTTGTGAGAAACCCTATGAATGCAGGGAGTGTGGAATGGCCTTTATTCGTAGTTCACAACTTACCGAACATCAGAGAAT
TCATCCTGGTATCAAACCTTACGAATGTAGAGAGTGTGGGCAGGCATTTATTCTTGGCTCACAACTCATTGAACACTACAGAATTCATAC
TGGTTAGAAAGCCTTGAGTGTAAGGGATAAAGATAAGCCTTTATGTGGAGTTCACATCTGGCTCAGTACTAGGTAATTTTTAATGTAGTG

>8583_8583_3_AXL-ZNF565_AXL_chr19_41762516_ENST00000301178_ZNF565_chr19_36686058_ENST00000392173_length(amino acids)=1231AA_BP=777
MAPMAWRCPRMGRVPLAWCLALCGWACMAPRGTQAEESPFVGNPGNITGARGLTGTLRCQLQVQGEPPEVHWLRDGQILELADSTQTQVP
LGEDEQDDWIVVSQLRITSLQLSDTGQYQCLVFLGHQTFVSQPGYVGLEGLPYFLEEPEDRTVAANTPFNLSCQAQGPPEPVDLLWLQDA
VPLATAPGHGPQRSLHVPGLNKTSSFSCEAHNAKGVTTSRTATITVLPQQPRNLHLVSRQPTELEVAWTPGLSGIYPLTHCTLQAVLSND
GMGIQAGEPDPPEEPLTSQASVPPHQLRLGSLHPHTPYHIRVACTSSQGPSSWTHWLPVETPEGVPLGPPENISATRNGSQAFVHWQEPR
APLQGTLLGYRLAYQGQDTPEVLMDIGLRQEVTLELQGDGSVSNLTVCVAAYTAAGDGPWSLPVPLEAWRPGQAQPVHQLVKEPSTPAFS
WPWWYVLLGAVVAAACVLILALFLVHRRKKETRYGEVFEPTVERGELVVRYRVRKSYSRRTTEATLNSLGISEELKEKLRDVMVDRHKVA
LGKTLGEGEFGAVMEGQLNQDDSILKVAVKTMKIAICTRSELEDFLSEAVCMKEFDHPNVMRLIGVCFQGSERESFPAPVVILPFMKHGD
LHSFLLYSRLGDQPVYLPTQMLVKFMADIASGMEYLSTKRFIHRDLAARNCMLNENMSVCVADFGLSKKIYNGDYYRQGRIAKMPVKWIA
IESLADRVYTSKSDVGLVTFRDVAIEFSLEEWKCLEPAQRDLYREVTLENFGHLASLGLSISKPDVVSLLEQGKEPWMIANDVTGPWCPD
LESRCEKFLQKDIFEIGAFNWEIMESLKCSDLEGSDFRADWECEGQFERQVNEECYFKQVNVTYGHMPVFQHHTSHTVRQSRETGEKLME
CHECGKAFSRGSHLIQHQKIHTGEKPFGCKECGKAFSRASHLVQHQRIHTGEKPYDCKDCGKAFGRTSELILHQRLHTGVKPYECKECGK
TFRQHSQLILHQRTHTGEKPYVCKDCGKAFIRGSQLTVHRRIHTGARPYECKECGKAFRQHSQLTVHQRIHTGEKPYECKECGKGFIHSS
EVTRHQRIHSGEKPYECKECGKAFRQHAQLTRHQRVHTGDRPYECKDCGKAFSRSSYLIQHQRIHTGDKPYECKECGKAFIRVSQLTHHQ

--------------------------------------------------------------
>8583_8583_4_AXL-ZNF565_AXL_chr19_41762516_ENST00000359092_ZNF565_chr19_36686058_ENST00000304116_length(transcript)=3998nt_BP=2327nt
GCTGGGCAGAGCCGGTGGCAAGGGCCTCCCCTGCCGCTGTGCCAGGCAGGCAGTGCCAAATCCGGGGAGCCTGGAGCTGGGGGGAGGGCC
GGGGACAGCCCGGCCCTGCCCCCTCCCCCGCTGGGAGCCCAACAACTTCTGAGGAAAGTTTGGCACCCATGGCGTGGCGGTGCCCCAGGA
TGGGCAGGGTCCCGCTGGCCTGGTGCTTGGCGCTGTGCGGCTGGGCGTGCATGGCCCCCAGGGGCACGCAGGCTGAAGAAAGTCCCTTCG
TGGGCAACCCAGGGAATATCACAGGTGCCCGGGGACTCACGGGCACCCTTCGGTGTCAGCTCCAGGTTCAGGGAGAGCCCCCCGAGGTAC
ATTGGCTTCGGGATGGACAGATCCTGGAGCTCGCGGACAGCACCCAGACCCAGGTGCCCCTGGGTGAGGATGAACAGGATGACTGGATAG
TGGTCAGCCAGCTCAGAATCACCTCCCTGCAGCTTTCCGACACGGGACAGTACCAGTGTTTGGTGTTTCTGGGACATCAGACCTTCGTGT
CCCAGCCTGGCTATGTTGGGCTGGAGGGCTTGCCTTACTTCCTGGAGGAGCCCGAAGACAGGACTGTGGCCGCCAACACCCCCTTCAACC
TGAGCTGCCAAGCTCAGGGACCCCCAGAGCCCGTGGACCTACTCTGGCTCCAGGATGCTGTCCCCCTGGCCACGGCTCCAGGTCACGGCC
CCCAGCGCAGCCTGCATGTTCCAGGGCTGAACAAGACATCCTCTTTCTCCTGCGAAGCCCATAACGCCAAGGGGGTCACCACATCCCGCA
CAGCCACCATCACAGTGCTCCCCCAGCAGCCCCGTAACCTCCACCTGGTCTCCCGCCAACCCACGGAGCTGGAGGTGGCTTGGACTCCAG
GCCTGAGCGGCATCTACCCCCTGACCCACTGCACCCTGCAGGCTGTGCTGTCAAACGATGGGATGGGCATCCAGGCGGGAGAACCAGACC
CCCCAGAGGAGCCCCTCACCTCGCAAGCATCCGTGCCCCCCCATCAGCTTCGGCTAGGCAGCCTCCATCCTCACACCCCTTATCACATCC
GCGTGGCATGCACCAGCAGCCAGGGCCCCTCATCCTGGACCCACTGGCTTCCTGTGGAGACGCCGGAGGGAGTGCCCCTGGGCCCCCCTG
AGAACATTAGTGCTACGCGGAATGGGAGCCAGGCCTTCGTGCATTGGCAAGAGCCCCGGGCGCCCCTGCAGGGTACCCTGTTAGGGTACC
GGCTGGCGTATCAAGGCCAGGACACCCCAGAGGTGCTAATGGACATAGGGCTAAGGCAAGAGGTGACCCTGGAGCTGCAGGGGGACGGGT
CTGTGTCCAATCTGACAGTGTGTGTGGCAGCCTACACTGCTGCTGGGGATGGACCCTGGAGCCTCCCAGTACCCCTGGAGGCCTGGCGCC
CAGTGAAGGAACCTTCAACTCCTGCCTTCTCGTGGCCCTGGTGGTATGTACTGCTAGGAGCAGTCGTGGCCGCTGCCTGTGTCCTCATCT
TGGCTCTCTTCCTTGTCCACCGGCGAAAGAAGGAGACCCGTTATGGAGAAGTGTTTGAACCAACAGTGGAAAGAGGTGAACTGGTAGTCA
GGTACCGCGTGCGCAAGTCCTACAGTCGTCGGACCACTGAAGCTACCTTGAACAGCCTGGGCATCAGTGAAGAGCTGAAGGAGAAGCTGC
GGGATGTGATGGTGGACCGGCACAAGGTGGCCCTGGGGAAGACTCTGGGAGAGGGAGAGTTTGGAGCTGTGATGGAAGGCCAGCTCAACC
AGGACGACTCCATCCTCAAGGTGGCTGTGAAGACGATGAAGATTGCCATCTGCACGAGGTCAGAGCTGGAGGATTTCCTGAGTGAAGCGG
TCTGCATGAAGGAATTTGACCATCCCAACGTCATGAGGCTCATCGGTGTCTGTTTCCAGGGTTCTGAACGAGAGAGCTTCCCAGCACCTG
TGGTCATCTTACCTTTCATGAAACATGGAGACCTACACAGCTTCCTCCTCTATTCCCGGCTCGGGGACCAGCCAGTGTACCTGCCCACTC
AGATGCTAGTGAAGTTCATGGCAGACATCGCCAGTGGCATGGAGTATCTGAGTACCAAGAGATTCATACACCGGGACCTGGCGGCCAGGA
ACTGCATGCTGAATGAGAACATGTCCGTGTGTGTGGCGGACTTCGGGCTCTCCAAGAAGATCTACAATGGGGACTACTACCGCCAGGGAC
GTATCGCCAAGATGCCAGTCAAGTGGATTGCCATTGAGAGTCTAGCTGACCGTGTCTACACCAGCAAGAGCGATGTGGGACTGGTGACAT
TCAGGGACGTGGCCATAGAGTTCTCTCTGGAAGAATGGAAGTGCCTGGAACCTGCTCAGAGGGACTTGTACAGGGAGGTGACTCTGGAGA
ACTTTGGTCACTTGGCCTCACTAGGACTCTCCATTTCTAAGCCTGATGTCGTCTCCTTATTGGAGCAAGGGAAAGAGCCCTGGATGATTG
CAAATGATGTGACAGGACCATGGTGCCCAGACTTGGAGTCCAGGTGTGAGAAATTTCTACAAAAAGACATTTTTGAAATCGGGGCATTCA
ACTGGGAGATAATGGAAAGCCTTAAATGCAGTGACCTGGAGGGCTCCGATTTTAGAGCTGACTGGGAATGCGAAGGCCAGTTTGAGAGAC
AAGTCAATGAAGAGTGCTATTTTAAGCAAGTGAACGTCACCTATGGACATATGCCCGTGTTCCAGCATCACACGTCTCACACTGTACGTC
AGAGCAGGGAGACTGGTGAGAAACTGATGGAATGTCATGAATGTGGGAAAGCATTTAGCCGTGGCTCACACCTTATTCAACATCAGAAAA
TTCACACTGGTGAAAAACCCTTTGGATGTAAGGAATGTGGGAAGGCCTTCAGCCGTGCCTCACACCTTGTTCAGCATCAGAGAATTCACA
CGGGTGAGAAACCTTATGACTGTAAGGACTGTGGGAAGGCCTTTGGTCGTACATCAGAACTTATTCTACATCAGAGACTTCATACTGGTG
TCAAACCTTATGAATGTAAAGAATGTGGGAAGACCTTTAGGCAGCATTCACAGCTGATTCTGCATCAAAGAACTCACACAGGCGAGAAAC
CCTACGTATGTAAAGACTGTGGCAAGGCTTTCATTCGTGGCTCCCAACTCACTGTGCATCGGAGAATCCACACAGGGGCCAGACCCTATG
AGTGTAAAGAATGCGGGAAAGCCTTTAGACAGCACTCACAGCTGACTGTACACCAGCGAATCCACACTGGTGAGAAACCCTACGAGTGTA
AGGAATGCGGAAAGGGCTTTATTCACAGCTCAGAAGTTACTCGACATCAAAGAATTCATTCTGGGGAGAAACCCTATGAGTGTAAGGAAT
GTGGGAAGGCCTTCAGACAGCACGCACAGCTCACACGACATCAGAGAGTCCATACTGGCGACAGACCCTATGAATGTAAGGACTGCGGGA
AGGCATTTAGTCGTAGCTCATACCTCATTCAACATCAAAGAATTCATACAGGTGACAAACCCTACGAATGTAAGGAATGTGGGAAGGCCT
TTATTCGTGTTTCACAACTGACTCATCATCAGCGAATTCACACTTGTGAGAAACCCTATGAATGCAGGGAGTGTGGAATGGCCTTTATTC
GTAGTTCACAACTTACCGAACATCAGAGAATTCATCCTGGTATCAAACCTTACGAATGTAGAGAGTGTGGGCAGGCATTTATTCTTGGCT
CACAACTCATTGAACACTACAGAATTCATACTGGTTAGAAAGCCTTGAGTGTAAGGGATAAAGATAAGCCTTTATGTGGAGTTCACATCT
GGCTCAGTACTAGGTAATTTTTAATGTAGTGTAATTAATGTCAGAAAACACCTGTCACTTCCATCATAGAACATCAGAAAACTCACACCC

>8583_8583_4_AXL-ZNF565_AXL_chr19_41762516_ENST00000359092_ZNF565_chr19_36686058_ENST00000304116_length(amino acids)=1222AA_BP=768
MAPMAWRCPRMGRVPLAWCLALCGWACMAPRGTQAEESPFVGNPGNITGARGLTGTLRCQLQVQGEPPEVHWLRDGQILELADSTQTQVP
LGEDEQDDWIVVSQLRITSLQLSDTGQYQCLVFLGHQTFVSQPGYVGLEGLPYFLEEPEDRTVAANTPFNLSCQAQGPPEPVDLLWLQDA
VPLATAPGHGPQRSLHVPGLNKTSSFSCEAHNAKGVTTSRTATITVLPQQPRNLHLVSRQPTELEVAWTPGLSGIYPLTHCTLQAVLSND
GMGIQAGEPDPPEEPLTSQASVPPHQLRLGSLHPHTPYHIRVACTSSQGPSSWTHWLPVETPEGVPLGPPENISATRNGSQAFVHWQEPR
APLQGTLLGYRLAYQGQDTPEVLMDIGLRQEVTLELQGDGSVSNLTVCVAAYTAAGDGPWSLPVPLEAWRPVKEPSTPAFSWPWWYVLLG
AVVAAACVLILALFLVHRRKKETRYGEVFEPTVERGELVVRYRVRKSYSRRTTEATLNSLGISEELKEKLRDVMVDRHKVALGKTLGEGE
FGAVMEGQLNQDDSILKVAVKTMKIAICTRSELEDFLSEAVCMKEFDHPNVMRLIGVCFQGSERESFPAPVVILPFMKHGDLHSFLLYSR
LGDQPVYLPTQMLVKFMADIASGMEYLSTKRFIHRDLAARNCMLNENMSVCVADFGLSKKIYNGDYYRQGRIAKMPVKWIAIESLADRVY
TSKSDVGLVTFRDVAIEFSLEEWKCLEPAQRDLYREVTLENFGHLASLGLSISKPDVVSLLEQGKEPWMIANDVTGPWCPDLESRCEKFL
QKDIFEIGAFNWEIMESLKCSDLEGSDFRADWECEGQFERQVNEECYFKQVNVTYGHMPVFQHHTSHTVRQSRETGEKLMECHECGKAFS
RGSHLIQHQKIHTGEKPFGCKECGKAFSRASHLVQHQRIHTGEKPYDCKDCGKAFGRTSELILHQRLHTGVKPYECKECGKTFRQHSQLI
LHQRTHTGEKPYVCKDCGKAFIRGSQLTVHRRIHTGARPYECKECGKAFRQHSQLTVHQRIHTGEKPYECKECGKGFIHSSEVTRHQRIH
SGEKPYECKECGKAFRQHAQLTRHQRVHTGDRPYECKDCGKAFSRSSYLIQHQRIHTGDKPYECKECGKAFIRVSQLTHHQRIHTCEKPY

--------------------------------------------------------------
>8583_8583_5_AXL-ZNF565_AXL_chr19_41762516_ENST00000359092_ZNF565_chr19_36686058_ENST00000355114_length(transcript)=3990nt_BP=2327nt
GCTGGGCAGAGCCGGTGGCAAGGGCCTCCCCTGCCGCTGTGCCAGGCAGGCAGTGCCAAATCCGGGGAGCCTGGAGCTGGGGGGAGGGCC
GGGGACAGCCCGGCCCTGCCCCCTCCCCCGCTGGGAGCCCAACAACTTCTGAGGAAAGTTTGGCACCCATGGCGTGGCGGTGCCCCAGGA
TGGGCAGGGTCCCGCTGGCCTGGTGCTTGGCGCTGTGCGGCTGGGCGTGCATGGCCCCCAGGGGCACGCAGGCTGAAGAAAGTCCCTTCG
TGGGCAACCCAGGGAATATCACAGGTGCCCGGGGACTCACGGGCACCCTTCGGTGTCAGCTCCAGGTTCAGGGAGAGCCCCCCGAGGTAC
ATTGGCTTCGGGATGGACAGATCCTGGAGCTCGCGGACAGCACCCAGACCCAGGTGCCCCTGGGTGAGGATGAACAGGATGACTGGATAG
TGGTCAGCCAGCTCAGAATCACCTCCCTGCAGCTTTCCGACACGGGACAGTACCAGTGTTTGGTGTTTCTGGGACATCAGACCTTCGTGT
CCCAGCCTGGCTATGTTGGGCTGGAGGGCTTGCCTTACTTCCTGGAGGAGCCCGAAGACAGGACTGTGGCCGCCAACACCCCCTTCAACC
TGAGCTGCCAAGCTCAGGGACCCCCAGAGCCCGTGGACCTACTCTGGCTCCAGGATGCTGTCCCCCTGGCCACGGCTCCAGGTCACGGCC
CCCAGCGCAGCCTGCATGTTCCAGGGCTGAACAAGACATCCTCTTTCTCCTGCGAAGCCCATAACGCCAAGGGGGTCACCACATCCCGCA
CAGCCACCATCACAGTGCTCCCCCAGCAGCCCCGTAACCTCCACCTGGTCTCCCGCCAACCCACGGAGCTGGAGGTGGCTTGGACTCCAG
GCCTGAGCGGCATCTACCCCCTGACCCACTGCACCCTGCAGGCTGTGCTGTCAAACGATGGGATGGGCATCCAGGCGGGAGAACCAGACC
CCCCAGAGGAGCCCCTCACCTCGCAAGCATCCGTGCCCCCCCATCAGCTTCGGCTAGGCAGCCTCCATCCTCACACCCCTTATCACATCC
GCGTGGCATGCACCAGCAGCCAGGGCCCCTCATCCTGGACCCACTGGCTTCCTGTGGAGACGCCGGAGGGAGTGCCCCTGGGCCCCCCTG
AGAACATTAGTGCTACGCGGAATGGGAGCCAGGCCTTCGTGCATTGGCAAGAGCCCCGGGCGCCCCTGCAGGGTACCCTGTTAGGGTACC
GGCTGGCGTATCAAGGCCAGGACACCCCAGAGGTGCTAATGGACATAGGGCTAAGGCAAGAGGTGACCCTGGAGCTGCAGGGGGACGGGT
CTGTGTCCAATCTGACAGTGTGTGTGGCAGCCTACACTGCTGCTGGGGATGGACCCTGGAGCCTCCCAGTACCCCTGGAGGCCTGGCGCC
CAGTGAAGGAACCTTCAACTCCTGCCTTCTCGTGGCCCTGGTGGTATGTACTGCTAGGAGCAGTCGTGGCCGCTGCCTGTGTCCTCATCT
TGGCTCTCTTCCTTGTCCACCGGCGAAAGAAGGAGACCCGTTATGGAGAAGTGTTTGAACCAACAGTGGAAAGAGGTGAACTGGTAGTCA
GGTACCGCGTGCGCAAGTCCTACAGTCGTCGGACCACTGAAGCTACCTTGAACAGCCTGGGCATCAGTGAAGAGCTGAAGGAGAAGCTGC
GGGATGTGATGGTGGACCGGCACAAGGTGGCCCTGGGGAAGACTCTGGGAGAGGGAGAGTTTGGAGCTGTGATGGAAGGCCAGCTCAACC
AGGACGACTCCATCCTCAAGGTGGCTGTGAAGACGATGAAGATTGCCATCTGCACGAGGTCAGAGCTGGAGGATTTCCTGAGTGAAGCGG
TCTGCATGAAGGAATTTGACCATCCCAACGTCATGAGGCTCATCGGTGTCTGTTTCCAGGGTTCTGAACGAGAGAGCTTCCCAGCACCTG
TGGTCATCTTACCTTTCATGAAACATGGAGACCTACACAGCTTCCTCCTCTATTCCCGGCTCGGGGACCAGCCAGTGTACCTGCCCACTC
AGATGCTAGTGAAGTTCATGGCAGACATCGCCAGTGGCATGGAGTATCTGAGTACCAAGAGATTCATACACCGGGACCTGGCGGCCAGGA
ACTGCATGCTGAATGAGAACATGTCCGTGTGTGTGGCGGACTTCGGGCTCTCCAAGAAGATCTACAATGGGGACTACTACCGCCAGGGAC
GTATCGCCAAGATGCCAGTCAAGTGGATTGCCATTGAGAGTCTAGCTGACCGTGTCTACACCAGCAAGAGCGATGTGGGACTGGTGACAT
TCAGGGACGTGGCCATAGAGTTCTCTCTGGAAGAATGGAAGTGCCTGGAACCTGCTCAGAGGGACTTGTACAGGGAGGTGACTCTGGAGA
ACTTTGGTCACTTGGCCTCACTAGGACTCTCCATTTCTAAGCCTGATGTCGTCTCCTTATTGGAGCAAGGGAAAGAGCCCTGGATGATTG
CAAATGATGTGACAGGACCATGGTGCCCAGACTTGGAGTCCAGGTGTGAGAAATTTCTACAAAAAGACATTTTTGAAATCGGGGCATTCA
ACTGGGAGATAATGGAAAGCCTTAAATGCAGTGACCTGGAGGGCTCCGATTTTAGAGCTGACTGGGAATGCGAAGGCCAGTTTGAGAGAC
AAGTCAATGAAGAGTGCTATTTTAAGCAAGTGAACGTCACCTATGGACATATGCCCGTGTTCCAGCATCACACGTCTCACACTGTACGTC
AGAGCAGGGAGACTGGTGAGAAACTGATGGAATGTCATGAATGTGGGAAAGCATTTAGCCGTGGCTCACACCTTATTCAACATCAGAAAA
TTCACACTGGTGAAAAACCCTTTGGATGTAAGGAATGTGGGAAGGCCTTCAGCCGTGCCTCACACCTTGTTCAGCATCAGAGAATTCACA
CGGGTGAGAAACCTTATGACTGTAAGGACTGTGGGAAGGCCTTTGGTCGTACATCAGAACTTATTCTACATCAGAGACTTCATACTGGTG
TCAAACCTTATGAATGTAAAGAATGTGGGAAGACCTTTAGGCAGCATTCACAGCTGATTCTGCATCAAAGAACTCACACAGGCGAGAAAC
CCTACGTATGTAAAGACTGTGGCAAGGCTTTCATTCGTGGCTCCCAACTCACTGTGCATCGGAGAATCCACACAGGGGCCAGACCCTATG
AGTGTAAAGAATGCGGGAAAGCCTTTAGACAGCACTCACAGCTGACTGTACACCAGCGAATCCACACTGGTGAGAAACCCTACGAGTGTA
AGGAATGCGGAAAGGGCTTTATTCACAGCTCAGAAGTTACTCGACATCAAAGAATTCATTCTGGGGAGAAACCCTATGAGTGTAAGGAAT
GTGGGAAGGCCTTCAGACAGCACGCACAGCTCACACGACATCAGAGAGTCCATACTGGCGACAGACCCTATGAATGTAAGGACTGCGGGA
AGGCATTTAGTCGTAGCTCATACCTCATTCAACATCAAAGAATTCATACAGGTGACAAACCCTACGAATGTAAGGAATGTGGGAAGGCCT
TTATTCGTGTTTCACAACTGACTCATCATCAGCGAATTCACACTTGTGAGAAACCCTATGAATGCAGGGAGTGTGGAATGGCCTTTATTC
GTAGTTCACAACTTACCGAACATCAGAGAATTCATCCTGGTATCAAACCTTACGAATGTAGAGAGTGTGGGCAGGCATTTATTCTTGGCT
CACAACTCATTGAACACTACAGAATTCATACTGGTTAGAAAGCCTTGAGTGTAAGGGATAAAGATAAGCCTTTATGTGGAGTTCACATCT
GGCTCAGTACTAGGTAATTTTTAATGTAGTGTAATTAATGTCAGAAAACACCTGTCACTTCCATCATAGAACATCAGAAAACTCACACCC

>8583_8583_5_AXL-ZNF565_AXL_chr19_41762516_ENST00000359092_ZNF565_chr19_36686058_ENST00000355114_length(amino acids)=1222AA_BP=768
MAPMAWRCPRMGRVPLAWCLALCGWACMAPRGTQAEESPFVGNPGNITGARGLTGTLRCQLQVQGEPPEVHWLRDGQILELADSTQTQVP
LGEDEQDDWIVVSQLRITSLQLSDTGQYQCLVFLGHQTFVSQPGYVGLEGLPYFLEEPEDRTVAANTPFNLSCQAQGPPEPVDLLWLQDA
VPLATAPGHGPQRSLHVPGLNKTSSFSCEAHNAKGVTTSRTATITVLPQQPRNLHLVSRQPTELEVAWTPGLSGIYPLTHCTLQAVLSND
GMGIQAGEPDPPEEPLTSQASVPPHQLRLGSLHPHTPYHIRVACTSSQGPSSWTHWLPVETPEGVPLGPPENISATRNGSQAFVHWQEPR
APLQGTLLGYRLAYQGQDTPEVLMDIGLRQEVTLELQGDGSVSNLTVCVAAYTAAGDGPWSLPVPLEAWRPVKEPSTPAFSWPWWYVLLG
AVVAAACVLILALFLVHRRKKETRYGEVFEPTVERGELVVRYRVRKSYSRRTTEATLNSLGISEELKEKLRDVMVDRHKVALGKTLGEGE
FGAVMEGQLNQDDSILKVAVKTMKIAICTRSELEDFLSEAVCMKEFDHPNVMRLIGVCFQGSERESFPAPVVILPFMKHGDLHSFLLYSR
LGDQPVYLPTQMLVKFMADIASGMEYLSTKRFIHRDLAARNCMLNENMSVCVADFGLSKKIYNGDYYRQGRIAKMPVKWIAIESLADRVY
TSKSDVGLVTFRDVAIEFSLEEWKCLEPAQRDLYREVTLENFGHLASLGLSISKPDVVSLLEQGKEPWMIANDVTGPWCPDLESRCEKFL
QKDIFEIGAFNWEIMESLKCSDLEGSDFRADWECEGQFERQVNEECYFKQVNVTYGHMPVFQHHTSHTVRQSRETGEKLMECHECGKAFS
RGSHLIQHQKIHTGEKPFGCKECGKAFSRASHLVQHQRIHTGEKPYDCKDCGKAFGRTSELILHQRLHTGVKPYECKECGKTFRQHSQLI
LHQRTHTGEKPYVCKDCGKAFIRGSQLTVHRRIHTGARPYECKECGKAFRQHSQLTVHQRIHTGEKPYECKECGKGFIHSSEVTRHQRIH
SGEKPYECKECGKAFRQHAQLTRHQRVHTGDRPYECKDCGKAFSRSSYLIQHQRIHTGDKPYECKECGKAFIRVSQLTHHQRIHTCEKPY

--------------------------------------------------------------
>8583_8583_6_AXL-ZNF565_AXL_chr19_41762516_ENST00000359092_ZNF565_chr19_36686058_ENST00000392173_length(transcript)=3990nt_BP=2327nt
GCTGGGCAGAGCCGGTGGCAAGGGCCTCCCCTGCCGCTGTGCCAGGCAGGCAGTGCCAAATCCGGGGAGCCTGGAGCTGGGGGGAGGGCC
GGGGACAGCCCGGCCCTGCCCCCTCCCCCGCTGGGAGCCCAACAACTTCTGAGGAAAGTTTGGCACCCATGGCGTGGCGGTGCCCCAGGA
TGGGCAGGGTCCCGCTGGCCTGGTGCTTGGCGCTGTGCGGCTGGGCGTGCATGGCCCCCAGGGGCACGCAGGCTGAAGAAAGTCCCTTCG
TGGGCAACCCAGGGAATATCACAGGTGCCCGGGGACTCACGGGCACCCTTCGGTGTCAGCTCCAGGTTCAGGGAGAGCCCCCCGAGGTAC
ATTGGCTTCGGGATGGACAGATCCTGGAGCTCGCGGACAGCACCCAGACCCAGGTGCCCCTGGGTGAGGATGAACAGGATGACTGGATAG
TGGTCAGCCAGCTCAGAATCACCTCCCTGCAGCTTTCCGACACGGGACAGTACCAGTGTTTGGTGTTTCTGGGACATCAGACCTTCGTGT
CCCAGCCTGGCTATGTTGGGCTGGAGGGCTTGCCTTACTTCCTGGAGGAGCCCGAAGACAGGACTGTGGCCGCCAACACCCCCTTCAACC
TGAGCTGCCAAGCTCAGGGACCCCCAGAGCCCGTGGACCTACTCTGGCTCCAGGATGCTGTCCCCCTGGCCACGGCTCCAGGTCACGGCC
CCCAGCGCAGCCTGCATGTTCCAGGGCTGAACAAGACATCCTCTTTCTCCTGCGAAGCCCATAACGCCAAGGGGGTCACCACATCCCGCA
CAGCCACCATCACAGTGCTCCCCCAGCAGCCCCGTAACCTCCACCTGGTCTCCCGCCAACCCACGGAGCTGGAGGTGGCTTGGACTCCAG
GCCTGAGCGGCATCTACCCCCTGACCCACTGCACCCTGCAGGCTGTGCTGTCAAACGATGGGATGGGCATCCAGGCGGGAGAACCAGACC
CCCCAGAGGAGCCCCTCACCTCGCAAGCATCCGTGCCCCCCCATCAGCTTCGGCTAGGCAGCCTCCATCCTCACACCCCTTATCACATCC
GCGTGGCATGCACCAGCAGCCAGGGCCCCTCATCCTGGACCCACTGGCTTCCTGTGGAGACGCCGGAGGGAGTGCCCCTGGGCCCCCCTG
AGAACATTAGTGCTACGCGGAATGGGAGCCAGGCCTTCGTGCATTGGCAAGAGCCCCGGGCGCCCCTGCAGGGTACCCTGTTAGGGTACC
GGCTGGCGTATCAAGGCCAGGACACCCCAGAGGTGCTAATGGACATAGGGCTAAGGCAAGAGGTGACCCTGGAGCTGCAGGGGGACGGGT
CTGTGTCCAATCTGACAGTGTGTGTGGCAGCCTACACTGCTGCTGGGGATGGACCCTGGAGCCTCCCAGTACCCCTGGAGGCCTGGCGCC
CAGTGAAGGAACCTTCAACTCCTGCCTTCTCGTGGCCCTGGTGGTATGTACTGCTAGGAGCAGTCGTGGCCGCTGCCTGTGTCCTCATCT
TGGCTCTCTTCCTTGTCCACCGGCGAAAGAAGGAGACCCGTTATGGAGAAGTGTTTGAACCAACAGTGGAAAGAGGTGAACTGGTAGTCA
GGTACCGCGTGCGCAAGTCCTACAGTCGTCGGACCACTGAAGCTACCTTGAACAGCCTGGGCATCAGTGAAGAGCTGAAGGAGAAGCTGC
GGGATGTGATGGTGGACCGGCACAAGGTGGCCCTGGGGAAGACTCTGGGAGAGGGAGAGTTTGGAGCTGTGATGGAAGGCCAGCTCAACC
AGGACGACTCCATCCTCAAGGTGGCTGTGAAGACGATGAAGATTGCCATCTGCACGAGGTCAGAGCTGGAGGATTTCCTGAGTGAAGCGG
TCTGCATGAAGGAATTTGACCATCCCAACGTCATGAGGCTCATCGGTGTCTGTTTCCAGGGTTCTGAACGAGAGAGCTTCCCAGCACCTG
TGGTCATCTTACCTTTCATGAAACATGGAGACCTACACAGCTTCCTCCTCTATTCCCGGCTCGGGGACCAGCCAGTGTACCTGCCCACTC
AGATGCTAGTGAAGTTCATGGCAGACATCGCCAGTGGCATGGAGTATCTGAGTACCAAGAGATTCATACACCGGGACCTGGCGGCCAGGA
ACTGCATGCTGAATGAGAACATGTCCGTGTGTGTGGCGGACTTCGGGCTCTCCAAGAAGATCTACAATGGGGACTACTACCGCCAGGGAC
GTATCGCCAAGATGCCAGTCAAGTGGATTGCCATTGAGAGTCTAGCTGACCGTGTCTACACCAGCAAGAGCGATGTGGGACTGGTGACAT
TCAGGGACGTGGCCATAGAGTTCTCTCTGGAAGAATGGAAGTGCCTGGAACCTGCTCAGAGGGACTTGTACAGGGAGGTGACTCTGGAGA
ACTTTGGTCACTTGGCCTCACTAGGACTCTCCATTTCTAAGCCTGATGTCGTCTCCTTATTGGAGCAAGGGAAAGAGCCCTGGATGATTG
CAAATGATGTGACAGGACCATGGTGCCCAGACTTGGAGTCCAGGTGTGAGAAATTTCTACAAAAAGACATTTTTGAAATCGGGGCATTCA
ACTGGGAGATAATGGAAAGCCTTAAATGCAGTGACCTGGAGGGCTCCGATTTTAGAGCTGACTGGGAATGCGAAGGCCAGTTTGAGAGAC
AAGTCAATGAAGAGTGCTATTTTAAGCAAGTGAACGTCACCTATGGACATATGCCCGTGTTCCAGCATCACACGTCTCACACTGTACGTC
AGAGCAGGGAGACTGGTGAGAAACTGATGGAATGTCATGAATGTGGGAAAGCATTTAGCCGTGGCTCACACCTTATTCAACATCAGAAAA
TTCACACTGGTGAAAAACCCTTTGGATGTAAGGAATGTGGGAAGGCCTTCAGCCGTGCCTCACACCTTGTTCAGCATCAGAGAATTCACA
CGGGTGAGAAACCTTATGACTGTAAGGACTGTGGGAAGGCCTTTGGTCGTACATCAGAACTTATTCTACATCAGAGACTTCATACTGGTG
TCAAACCTTATGAATGTAAAGAATGTGGGAAGACCTTTAGGCAGCATTCACAGCTGATTCTGCATCAAAGAACTCACACAGGCGAGAAAC
CCTACGTATGTAAAGACTGTGGCAAGGCTTTCATTCGTGGCTCCCAACTCACTGTGCATCGGAGAATCCACACAGGGGCCAGACCCTATG
AGTGTAAAGAATGCGGGAAAGCCTTTAGACAGCACTCACAGCTGACTGTACACCAGCGAATCCACACTGGTGAGAAACCCTACGAGTGTA
AGGAATGCGGAAAGGGCTTTATTCACAGCTCAGAAGTTACTCGACATCAAAGAATTCATTCTGGGGAGAAACCCTATGAGTGTAAGGAAT
GTGGGAAGGCCTTCAGACAGCACGCACAGCTCACACGACATCAGAGAGTCCATACTGGCGACAGACCCTATGAATGTAAGGACTGCGGGA
AGGCATTTAGTCGTAGCTCATACCTCATTCAACATCAAAGAATTCATACAGGTGACAAACCCTACGAATGTAAGGAATGTGGGAAGGCCT
TTATTCGTGTTTCACAACTGACTCATCATCAGCGAATTCACACTTGTGAGAAACCCTATGAATGCAGGGAGTGTGGAATGGCCTTTATTC
GTAGTTCACAACTTACCGAACATCAGAGAATTCATCCTGGTATCAAACCTTACGAATGTAGAGAGTGTGGGCAGGCATTTATTCTTGGCT
CACAACTCATTGAACACTACAGAATTCATACTGGTTAGAAAGCCTTGAGTGTAAGGGATAAAGATAAGCCTTTATGTGGAGTTCACATCT
GGCTCAGTACTAGGTAATTTTTAATGTAGTGTAATTAATGTCAGAAAACACCTGTCACTTCCATCATAGAACATCAGAAAACTCACACCC

>8583_8583_6_AXL-ZNF565_AXL_chr19_41762516_ENST00000359092_ZNF565_chr19_36686058_ENST00000392173_length(amino acids)=1222AA_BP=768
MAPMAWRCPRMGRVPLAWCLALCGWACMAPRGTQAEESPFVGNPGNITGARGLTGTLRCQLQVQGEPPEVHWLRDGQILELADSTQTQVP
LGEDEQDDWIVVSQLRITSLQLSDTGQYQCLVFLGHQTFVSQPGYVGLEGLPYFLEEPEDRTVAANTPFNLSCQAQGPPEPVDLLWLQDA
VPLATAPGHGPQRSLHVPGLNKTSSFSCEAHNAKGVTTSRTATITVLPQQPRNLHLVSRQPTELEVAWTPGLSGIYPLTHCTLQAVLSND
GMGIQAGEPDPPEEPLTSQASVPPHQLRLGSLHPHTPYHIRVACTSSQGPSSWTHWLPVETPEGVPLGPPENISATRNGSQAFVHWQEPR
APLQGTLLGYRLAYQGQDTPEVLMDIGLRQEVTLELQGDGSVSNLTVCVAAYTAAGDGPWSLPVPLEAWRPVKEPSTPAFSWPWWYVLLG
AVVAAACVLILALFLVHRRKKETRYGEVFEPTVERGELVVRYRVRKSYSRRTTEATLNSLGISEELKEKLRDVMVDRHKVALGKTLGEGE
FGAVMEGQLNQDDSILKVAVKTMKIAICTRSELEDFLSEAVCMKEFDHPNVMRLIGVCFQGSERESFPAPVVILPFMKHGDLHSFLLYSR
LGDQPVYLPTQMLVKFMADIASGMEYLSTKRFIHRDLAARNCMLNENMSVCVADFGLSKKIYNGDYYRQGRIAKMPVKWIAIESLADRVY
TSKSDVGLVTFRDVAIEFSLEEWKCLEPAQRDLYREVTLENFGHLASLGLSISKPDVVSLLEQGKEPWMIANDVTGPWCPDLESRCEKFL
QKDIFEIGAFNWEIMESLKCSDLEGSDFRADWECEGQFERQVNEECYFKQVNVTYGHMPVFQHHTSHTVRQSRETGEKLMECHECGKAFS
RGSHLIQHQKIHTGEKPFGCKECGKAFSRASHLVQHQRIHTGEKPYDCKDCGKAFGRTSELILHQRLHTGVKPYECKECGKTFRQHSQLI
LHQRTHTGEKPYVCKDCGKAFIRGSQLTVHRRIHTGARPYECKECGKAFRQHSQLTVHQRIHTGEKPYECKECGKGFIHSSEVTRHQRIH
SGEKPYECKECGKAFRQHAQLTRHQRVHTGDRPYECKDCGKAFSRSSYLIQHQRIHTGDKPYECKECGKAFIRVSQLTHHQRIHTCEKPY

--------------------------------------------------------------
>8583_8583_7_AXL-ZNF565_AXL_chr19_41762516_ENST00000593513_ZNF565_chr19_36686058_ENST00000304116_length(transcript)=3439nt_BP=1768nt
AGCACACGCGTAAACAACACGCAGAACTGCAGTCGCACTTACAAGACTTGGTCCCAGGGCCGGGCACCGAGTGGCTCTGCCTGCGATCCA
GCACTTTGGGAGGCCGAGGCGGGAGGATCGCTTGGGGCCAGAAGTTTGAGAGCAGCCTGGGCAACGTGGGCTGAACAAGACATCCTCTTT
CTCCTGCGAAGCCCATAACGCCAAGGGGGTCACCACATCCCGCACAGCCACCATCACAGTGCTCCCCCAGCAGCCCCGTAACCTCCACCT
GGTCTCCCGCCAACCCACGGAGCTGGAGGTGGCTTGGACTCCAGGCCTGAGCGGCATCTACCCCCTGACCCACTGCACCCTGCAGGCTGT
GCTGTCAAACGATGGGATGGGCATCCAGGCGGGAGAACCAGACCCCCCAGAGGAGCCCCTCACCTCGCAAGCATCCGTGCCCCCCCATCA
GCTTCGGCTAGGCAGCCTCCATCCTCACACCCCTTATCACATCCGCGTGGCATGCACCAGCAGCCAGGGCCCCTCATCCTGGACCCACTG
GCTTCCTGTGGAGACGCCGGAGGGAGTGCCCCTGGGCCCCCCTGAGAACATTAGTGCTACGCGGAATGGGAGCCAGGCCTTCGTGCATTG
GCAAGAGCCCCGGGCGCCCCTGCAGGGTACCCTGTTAGGGTACCGGCTGGCGTATCAAGGCCAGGACACCCCAGAGGTGCTAATGGACAT
AGGGCTAAGGCAAGAGGTGACCCTGGAGCTGCAGGGGGACGGGTCTGTGTCCAATCTGACAGTGTGTGTGGCAGCCTACACTGCTGCTGG
GGATGGACCCTGGAGCCTCCCAGTACCCCTGGAGGCCTGGCGCCCAGGGCAAGCACAGCCAGTCCACCAGCTGGTGAAGGAACCTTCAAC
TCCTGCCTTCTCGTGGCCCTGGTGGTATGTACTGCTAGGAGCAGTCGTGGCCGCTGCCTGTGTCCTCATCTTGGCTCTCTTCCTTGTCCA
CCGGCGAAAGAAGGAGACCCGTTATGGAGAAGTGTTTGAACCAACAGTGGAAAGAGGTGAACTGGTAGTCAGGTACCGCGTGCGCAAGTC
CTACAGTCGTCGGACCACTGAAGCTACCTTGAACAGCCTGGGCATCAGTGAAGAGCTGAAGGAGAAGCTGCGGGATGTGATGGTGGACCG
GCACAAGGTGGCCCTGGGGAAGACTCTGGGAGAGGGAGAGTTTGGAGCTGTGATGGAAGGCCAGCTCAACCAGGACGACTCCATCCTCAA
GGTGGCTGTGAAGACGATGAAGATTGCCATCTGCACGAGGTCAGAGCTGGAGGATTTCCTGAGTGAAGCGGTCTGCATGAAGGAATTTGA
CCATCCCAACGTCATGAGGCTCATCGGTGTCTGTTTCCAGGGTTCTGAACGAGAGAGCTTCCCAGCACCTGTGGTCATCTTACCTTTCAT
GAAACATGGAGACCTACACAGCTTCCTCCTCTATTCCCGGCTCGGGGACCAGCCAGTGTACCTGCCCACTCAGATGCTAGTGAAGTTCAT
GGCAGACATCGCCAGTGGCATGGAGTATCTGAGTACCAAGAGATTCATACACCGGGACCTGGCGGCCAGGAACTGCATGCTGAATGAGAA
CATGTCCGTGTGTGTGGCGGACTTCGGGCTCTCCAAGAAGATCTACAATGGGGACTACTACCGCCAGGGACGTATCGCCAAGATGCCAGT
CAAGTGGATTGCCATTGAGAGTCTAGCTGACCGTGTCTACACCAGCAAGAGCGATGTGGGACTGGTGACATTCAGGGACGTGGCCATAGA
GTTCTCTCTGGAAGAATGGAAGTGCCTGGAACCTGCTCAGAGGGACTTGTACAGGGAGGTGACTCTGGAGAACTTTGGTCACTTGGCCTC
ACTAGGACTCTCCATTTCTAAGCCTGATGTCGTCTCCTTATTGGAGCAAGGGAAAGAGCCCTGGATGATTGCAAATGATGTGACAGGACC
ATGGTGCCCAGACTTGGAGTCCAGGTGTGAGAAATTTCTACAAAAAGACATTTTTGAAATCGGGGCATTCAACTGGGAGATAATGGAAAG
CCTTAAATGCAGTGACCTGGAGGGCTCCGATTTTAGAGCTGACTGGGAATGCGAAGGCCAGTTTGAGAGACAAGTCAATGAAGAGTGCTA
TTTTAAGCAAGTGAACGTCACCTATGGACATATGCCCGTGTTCCAGCATCACACGTCTCACACTGTACGTCAGAGCAGGGAGACTGGTGA
GAAACTGATGGAATGTCATGAATGTGGGAAAGCATTTAGCCGTGGCTCACACCTTATTCAACATCAGAAAATTCACACTGGTGAAAAACC
CTTTGGATGTAAGGAATGTGGGAAGGCCTTCAGCCGTGCCTCACACCTTGTTCAGCATCAGAGAATTCACACGGGTGAGAAACCTTATGA
CTGTAAGGACTGTGGGAAGGCCTTTGGTCGTACATCAGAACTTATTCTACATCAGAGACTTCATACTGGTGTCAAACCTTATGAATGTAA
AGAATGTGGGAAGACCTTTAGGCAGCATTCACAGCTGATTCTGCATCAAAGAACTCACACAGGCGAGAAACCCTACGTATGTAAAGACTG
TGGCAAGGCTTTCATTCGTGGCTCCCAACTCACTGTGCATCGGAGAATCCACACAGGGGCCAGACCCTATGAGTGTAAAGAATGCGGGAA
AGCCTTTAGACAGCACTCACAGCTGACTGTACACCAGCGAATCCACACTGGTGAGAAACCCTACGAGTGTAAGGAATGCGGAAAGGGCTT
TATTCACAGCTCAGAAGTTACTCGACATCAAAGAATTCATTCTGGGGAGAAACCCTATGAGTGTAAGGAATGTGGGAAGGCCTTCAGACA
GCACGCACAGCTCACACGACATCAGAGAGTCCATACTGGCGACAGACCCTATGAATGTAAGGACTGCGGGAAGGCATTTAGTCGTAGCTC
ATACCTCATTCAACATCAAAGAATTCATACAGGTGACAAACCCTACGAATGTAAGGAATGTGGGAAGGCCTTTATTCGTGTTTCACAACT
GACTCATCATCAGCGAATTCACACTTGTGAGAAACCCTATGAATGCAGGGAGTGTGGAATGGCCTTTATTCGTAGTTCACAACTTACCGA
ACATCAGAGAATTCATCCTGGTATCAAACCTTACGAATGTAGAGAGTGTGGGCAGGCATTTATTCTTGGCTCACAACTCATTGAACACTA
CAGAATTCATACTGGTTAGAAAGCCTTGAGTGTAAGGGATAAAGATAAGCCTTTATGTGGAGTTCACATCTGGCTCAGTACTAGGTAATT
TTTAATGTAGTGTAATTAATGTCAGAAAACACCTGTCACTTCCATCATAGAACATCAGAAAACTCACACCCAAAGAAAATTAAATAAATG

>8583_8583_7_AXL-ZNF565_AXL_chr19_41762516_ENST00000593513_ZNF565_chr19_36686058_ENST00000304116_length(amino acids)=1032AA_BP=578
MNKTSSFSCEAHNAKGVTTSRTATITVLPQQPRNLHLVSRQPTELEVAWTPGLSGIYPLTHCTLQAVLSNDGMGIQAGEPDPPEEPLTSQ
ASVPPHQLRLGSLHPHTPYHIRVACTSSQGPSSWTHWLPVETPEGVPLGPPENISATRNGSQAFVHWQEPRAPLQGTLLGYRLAYQGQDT
PEVLMDIGLRQEVTLELQGDGSVSNLTVCVAAYTAAGDGPWSLPVPLEAWRPGQAQPVHQLVKEPSTPAFSWPWWYVLLGAVVAAACVLI
LALFLVHRRKKETRYGEVFEPTVERGELVVRYRVRKSYSRRTTEATLNSLGISEELKEKLRDVMVDRHKVALGKTLGEGEFGAVMEGQLN
QDDSILKVAVKTMKIAICTRSELEDFLSEAVCMKEFDHPNVMRLIGVCFQGSERESFPAPVVILPFMKHGDLHSFLLYSRLGDQPVYLPT
QMLVKFMADIASGMEYLSTKRFIHRDLAARNCMLNENMSVCVADFGLSKKIYNGDYYRQGRIAKMPVKWIAIESLADRVYTSKSDVGLVT
FRDVAIEFSLEEWKCLEPAQRDLYREVTLENFGHLASLGLSISKPDVVSLLEQGKEPWMIANDVTGPWCPDLESRCEKFLQKDIFEIGAF
NWEIMESLKCSDLEGSDFRADWECEGQFERQVNEECYFKQVNVTYGHMPVFQHHTSHTVRQSRETGEKLMECHECGKAFSRGSHLIQHQK
IHTGEKPFGCKECGKAFSRASHLVQHQRIHTGEKPYDCKDCGKAFGRTSELILHQRLHTGVKPYECKECGKTFRQHSQLILHQRTHTGEK
PYVCKDCGKAFIRGSQLTVHRRIHTGARPYECKECGKAFRQHSQLTVHQRIHTGEKPYECKECGKGFIHSSEVTRHQRIHSGEKPYECKE
CGKAFRQHAQLTRHQRVHTGDRPYECKDCGKAFSRSSYLIQHQRIHTGDKPYECKECGKAFIRVSQLTHHQRIHTCEKPYECRECGMAFI

--------------------------------------------------------------
>8583_8583_8_AXL-ZNF565_AXL_chr19_41762516_ENST00000593513_ZNF565_chr19_36686058_ENST00000355114_length(transcript)=3431nt_BP=1768nt
AGCACACGCGTAAACAACACGCAGAACTGCAGTCGCACTTACAAGACTTGGTCCCAGGGCCGGGCACCGAGTGGCTCTGCCTGCGATCCA
GCACTTTGGGAGGCCGAGGCGGGAGGATCGCTTGGGGCCAGAAGTTTGAGAGCAGCCTGGGCAACGTGGGCTGAACAAGACATCCTCTTT
CTCCTGCGAAGCCCATAACGCCAAGGGGGTCACCACATCCCGCACAGCCACCATCACAGTGCTCCCCCAGCAGCCCCGTAACCTCCACCT
GGTCTCCCGCCAACCCACGGAGCTGGAGGTGGCTTGGACTCCAGGCCTGAGCGGCATCTACCCCCTGACCCACTGCACCCTGCAGGCTGT
GCTGTCAAACGATGGGATGGGCATCCAGGCGGGAGAACCAGACCCCCCAGAGGAGCCCCTCACCTCGCAAGCATCCGTGCCCCCCCATCA
GCTTCGGCTAGGCAGCCTCCATCCTCACACCCCTTATCACATCCGCGTGGCATGCACCAGCAGCCAGGGCCCCTCATCCTGGACCCACTG
GCTTCCTGTGGAGACGCCGGAGGGAGTGCCCCTGGGCCCCCCTGAGAACATTAGTGCTACGCGGAATGGGAGCCAGGCCTTCGTGCATTG
GCAAGAGCCCCGGGCGCCCCTGCAGGGTACCCTGTTAGGGTACCGGCTGGCGTATCAAGGCCAGGACACCCCAGAGGTGCTAATGGACAT
AGGGCTAAGGCAAGAGGTGACCCTGGAGCTGCAGGGGGACGGGTCTGTGTCCAATCTGACAGTGTGTGTGGCAGCCTACACTGCTGCTGG
GGATGGACCCTGGAGCCTCCCAGTACCCCTGGAGGCCTGGCGCCCAGGGCAAGCACAGCCAGTCCACCAGCTGGTGAAGGAACCTTCAAC
TCCTGCCTTCTCGTGGCCCTGGTGGTATGTACTGCTAGGAGCAGTCGTGGCCGCTGCCTGTGTCCTCATCTTGGCTCTCTTCCTTGTCCA
CCGGCGAAAGAAGGAGACCCGTTATGGAGAAGTGTTTGAACCAACAGTGGAAAGAGGTGAACTGGTAGTCAGGTACCGCGTGCGCAAGTC
CTACAGTCGTCGGACCACTGAAGCTACCTTGAACAGCCTGGGCATCAGTGAAGAGCTGAAGGAGAAGCTGCGGGATGTGATGGTGGACCG
GCACAAGGTGGCCCTGGGGAAGACTCTGGGAGAGGGAGAGTTTGGAGCTGTGATGGAAGGCCAGCTCAACCAGGACGACTCCATCCTCAA
GGTGGCTGTGAAGACGATGAAGATTGCCATCTGCACGAGGTCAGAGCTGGAGGATTTCCTGAGTGAAGCGGTCTGCATGAAGGAATTTGA
CCATCCCAACGTCATGAGGCTCATCGGTGTCTGTTTCCAGGGTTCTGAACGAGAGAGCTTCCCAGCACCTGTGGTCATCTTACCTTTCAT
GAAACATGGAGACCTACACAGCTTCCTCCTCTATTCCCGGCTCGGGGACCAGCCAGTGTACCTGCCCACTCAGATGCTAGTGAAGTTCAT
GGCAGACATCGCCAGTGGCATGGAGTATCTGAGTACCAAGAGATTCATACACCGGGACCTGGCGGCCAGGAACTGCATGCTGAATGAGAA
CATGTCCGTGTGTGTGGCGGACTTCGGGCTCTCCAAGAAGATCTACAATGGGGACTACTACCGCCAGGGACGTATCGCCAAGATGCCAGT
CAAGTGGATTGCCATTGAGAGTCTAGCTGACCGTGTCTACACCAGCAAGAGCGATGTGGGACTGGTGACATTCAGGGACGTGGCCATAGA
GTTCTCTCTGGAAGAATGGAAGTGCCTGGAACCTGCTCAGAGGGACTTGTACAGGGAGGTGACTCTGGAGAACTTTGGTCACTTGGCCTC
ACTAGGACTCTCCATTTCTAAGCCTGATGTCGTCTCCTTATTGGAGCAAGGGAAAGAGCCCTGGATGATTGCAAATGATGTGACAGGACC
ATGGTGCCCAGACTTGGAGTCCAGGTGTGAGAAATTTCTACAAAAAGACATTTTTGAAATCGGGGCATTCAACTGGGAGATAATGGAAAG
CCTTAAATGCAGTGACCTGGAGGGCTCCGATTTTAGAGCTGACTGGGAATGCGAAGGCCAGTTTGAGAGACAAGTCAATGAAGAGTGCTA
TTTTAAGCAAGTGAACGTCACCTATGGACATATGCCCGTGTTCCAGCATCACACGTCTCACACTGTACGTCAGAGCAGGGAGACTGGTGA
GAAACTGATGGAATGTCATGAATGTGGGAAAGCATTTAGCCGTGGCTCACACCTTATTCAACATCAGAAAATTCACACTGGTGAAAAACC
CTTTGGATGTAAGGAATGTGGGAAGGCCTTCAGCCGTGCCTCACACCTTGTTCAGCATCAGAGAATTCACACGGGTGAGAAACCTTATGA
CTGTAAGGACTGTGGGAAGGCCTTTGGTCGTACATCAGAACTTATTCTACATCAGAGACTTCATACTGGTGTCAAACCTTATGAATGTAA
AGAATGTGGGAAGACCTTTAGGCAGCATTCACAGCTGATTCTGCATCAAAGAACTCACACAGGCGAGAAACCCTACGTATGTAAAGACTG
TGGCAAGGCTTTCATTCGTGGCTCCCAACTCACTGTGCATCGGAGAATCCACACAGGGGCCAGACCCTATGAGTGTAAAGAATGCGGGAA
AGCCTTTAGACAGCACTCACAGCTGACTGTACACCAGCGAATCCACACTGGTGAGAAACCCTACGAGTGTAAGGAATGCGGAAAGGGCTT
TATTCACAGCTCAGAAGTTACTCGACATCAAAGAATTCATTCTGGGGAGAAACCCTATGAGTGTAAGGAATGTGGGAAGGCCTTCAGACA
GCACGCACAGCTCACACGACATCAGAGAGTCCATACTGGCGACAGACCCTATGAATGTAAGGACTGCGGGAAGGCATTTAGTCGTAGCTC
ATACCTCATTCAACATCAAAGAATTCATACAGGTGACAAACCCTACGAATGTAAGGAATGTGGGAAGGCCTTTATTCGTGTTTCACAACT
GACTCATCATCAGCGAATTCACACTTGTGAGAAACCCTATGAATGCAGGGAGTGTGGAATGGCCTTTATTCGTAGTTCACAACTTACCGA
ACATCAGAGAATTCATCCTGGTATCAAACCTTACGAATGTAGAGAGTGTGGGCAGGCATTTATTCTTGGCTCACAACTCATTGAACACTA
CAGAATTCATACTGGTTAGAAAGCCTTGAGTGTAAGGGATAAAGATAAGCCTTTATGTGGAGTTCACATCTGGCTCAGTACTAGGTAATT
TTTAATGTAGTGTAATTAATGTCAGAAAACACCTGTCACTTCCATCATAGAACATCAGAAAACTCACACCCAAAGAAAATTAAATAAATG

>8583_8583_8_AXL-ZNF565_AXL_chr19_41762516_ENST00000593513_ZNF565_chr19_36686058_ENST00000355114_length(amino acids)=1032AA_BP=578
MNKTSSFSCEAHNAKGVTTSRTATITVLPQQPRNLHLVSRQPTELEVAWTPGLSGIYPLTHCTLQAVLSNDGMGIQAGEPDPPEEPLTSQ
ASVPPHQLRLGSLHPHTPYHIRVACTSSQGPSSWTHWLPVETPEGVPLGPPENISATRNGSQAFVHWQEPRAPLQGTLLGYRLAYQGQDT
PEVLMDIGLRQEVTLELQGDGSVSNLTVCVAAYTAAGDGPWSLPVPLEAWRPGQAQPVHQLVKEPSTPAFSWPWWYVLLGAVVAAACVLI
LALFLVHRRKKETRYGEVFEPTVERGELVVRYRVRKSYSRRTTEATLNSLGISEELKEKLRDVMVDRHKVALGKTLGEGEFGAVMEGQLN
QDDSILKVAVKTMKIAICTRSELEDFLSEAVCMKEFDHPNVMRLIGVCFQGSERESFPAPVVILPFMKHGDLHSFLLYSRLGDQPVYLPT
QMLVKFMADIASGMEYLSTKRFIHRDLAARNCMLNENMSVCVADFGLSKKIYNGDYYRQGRIAKMPVKWIAIESLADRVYTSKSDVGLVT
FRDVAIEFSLEEWKCLEPAQRDLYREVTLENFGHLASLGLSISKPDVVSLLEQGKEPWMIANDVTGPWCPDLESRCEKFLQKDIFEIGAF
NWEIMESLKCSDLEGSDFRADWECEGQFERQVNEECYFKQVNVTYGHMPVFQHHTSHTVRQSRETGEKLMECHECGKAFSRGSHLIQHQK
IHTGEKPFGCKECGKAFSRASHLVQHQRIHTGEKPYDCKDCGKAFGRTSELILHQRLHTGVKPYECKECGKTFRQHSQLILHQRTHTGEK
PYVCKDCGKAFIRGSQLTVHRRIHTGARPYECKECGKAFRQHSQLTVHQRIHTGEKPYECKECGKGFIHSSEVTRHQRIHSGEKPYECKE
CGKAFRQHAQLTRHQRVHTGDRPYECKDCGKAFSRSSYLIQHQRIHTGDKPYECKECGKAFIRVSQLTHHQRIHTCEKPYECRECGMAFI

--------------------------------------------------------------
>8583_8583_9_AXL-ZNF565_AXL_chr19_41762516_ENST00000593513_ZNF565_chr19_36686058_ENST00000392173_length(transcript)=3431nt_BP=1768nt
AGCACACGCGTAAACAACACGCAGAACTGCAGTCGCACTTACAAGACTTGGTCCCAGGGCCGGGCACCGAGTGGCTCTGCCTGCGATCCA
GCACTTTGGGAGGCCGAGGCGGGAGGATCGCTTGGGGCCAGAAGTTTGAGAGCAGCCTGGGCAACGTGGGCTGAACAAGACATCCTCTTT
CTCCTGCGAAGCCCATAACGCCAAGGGGGTCACCACATCCCGCACAGCCACCATCACAGTGCTCCCCCAGCAGCCCCGTAACCTCCACCT
GGTCTCCCGCCAACCCACGGAGCTGGAGGTGGCTTGGACTCCAGGCCTGAGCGGCATCTACCCCCTGACCCACTGCACCCTGCAGGCTGT
GCTGTCAAACGATGGGATGGGCATCCAGGCGGGAGAACCAGACCCCCCAGAGGAGCCCCTCACCTCGCAAGCATCCGTGCCCCCCCATCA
GCTTCGGCTAGGCAGCCTCCATCCTCACACCCCTTATCACATCCGCGTGGCATGCACCAGCAGCCAGGGCCCCTCATCCTGGACCCACTG
GCTTCCTGTGGAGACGCCGGAGGGAGTGCCCCTGGGCCCCCCTGAGAACATTAGTGCTACGCGGAATGGGAGCCAGGCCTTCGTGCATTG
GCAAGAGCCCCGGGCGCCCCTGCAGGGTACCCTGTTAGGGTACCGGCTGGCGTATCAAGGCCAGGACACCCCAGAGGTGCTAATGGACAT
AGGGCTAAGGCAAGAGGTGACCCTGGAGCTGCAGGGGGACGGGTCTGTGTCCAATCTGACAGTGTGTGTGGCAGCCTACACTGCTGCTGG
GGATGGACCCTGGAGCCTCCCAGTACCCCTGGAGGCCTGGCGCCCAGGGCAAGCACAGCCAGTCCACCAGCTGGTGAAGGAACCTTCAAC
TCCTGCCTTCTCGTGGCCCTGGTGGTATGTACTGCTAGGAGCAGTCGTGGCCGCTGCCTGTGTCCTCATCTTGGCTCTCTTCCTTGTCCA
CCGGCGAAAGAAGGAGACCCGTTATGGAGAAGTGTTTGAACCAACAGTGGAAAGAGGTGAACTGGTAGTCAGGTACCGCGTGCGCAAGTC
CTACAGTCGTCGGACCACTGAAGCTACCTTGAACAGCCTGGGCATCAGTGAAGAGCTGAAGGAGAAGCTGCGGGATGTGATGGTGGACCG
GCACAAGGTGGCCCTGGGGAAGACTCTGGGAGAGGGAGAGTTTGGAGCTGTGATGGAAGGCCAGCTCAACCAGGACGACTCCATCCTCAA
GGTGGCTGTGAAGACGATGAAGATTGCCATCTGCACGAGGTCAGAGCTGGAGGATTTCCTGAGTGAAGCGGTCTGCATGAAGGAATTTGA
CCATCCCAACGTCATGAGGCTCATCGGTGTCTGTTTCCAGGGTTCTGAACGAGAGAGCTTCCCAGCACCTGTGGTCATCTTACCTTTCAT
GAAACATGGAGACCTACACAGCTTCCTCCTCTATTCCCGGCTCGGGGACCAGCCAGTGTACCTGCCCACTCAGATGCTAGTGAAGTTCAT
GGCAGACATCGCCAGTGGCATGGAGTATCTGAGTACCAAGAGATTCATACACCGGGACCTGGCGGCCAGGAACTGCATGCTGAATGAGAA
CATGTCCGTGTGTGTGGCGGACTTCGGGCTCTCCAAGAAGATCTACAATGGGGACTACTACCGCCAGGGACGTATCGCCAAGATGCCAGT
CAAGTGGATTGCCATTGAGAGTCTAGCTGACCGTGTCTACACCAGCAAGAGCGATGTGGGACTGGTGACATTCAGGGACGTGGCCATAGA
GTTCTCTCTGGAAGAATGGAAGTGCCTGGAACCTGCTCAGAGGGACTTGTACAGGGAGGTGACTCTGGAGAACTTTGGTCACTTGGCCTC
ACTAGGACTCTCCATTTCTAAGCCTGATGTCGTCTCCTTATTGGAGCAAGGGAAAGAGCCCTGGATGATTGCAAATGATGTGACAGGACC
ATGGTGCCCAGACTTGGAGTCCAGGTGTGAGAAATTTCTACAAAAAGACATTTTTGAAATCGGGGCATTCAACTGGGAGATAATGGAAAG
CCTTAAATGCAGTGACCTGGAGGGCTCCGATTTTAGAGCTGACTGGGAATGCGAAGGCCAGTTTGAGAGACAAGTCAATGAAGAGTGCTA
TTTTAAGCAAGTGAACGTCACCTATGGACATATGCCCGTGTTCCAGCATCACACGTCTCACACTGTACGTCAGAGCAGGGAGACTGGTGA
GAAACTGATGGAATGTCATGAATGTGGGAAAGCATTTAGCCGTGGCTCACACCTTATTCAACATCAGAAAATTCACACTGGTGAAAAACC
CTTTGGATGTAAGGAATGTGGGAAGGCCTTCAGCCGTGCCTCACACCTTGTTCAGCATCAGAGAATTCACACGGGTGAGAAACCTTATGA
CTGTAAGGACTGTGGGAAGGCCTTTGGTCGTACATCAGAACTTATTCTACATCAGAGACTTCATACTGGTGTCAAACCTTATGAATGTAA
AGAATGTGGGAAGACCTTTAGGCAGCATTCACAGCTGATTCTGCATCAAAGAACTCACACAGGCGAGAAACCCTACGTATGTAAAGACTG
TGGCAAGGCTTTCATTCGTGGCTCCCAACTCACTGTGCATCGGAGAATCCACACAGGGGCCAGACCCTATGAGTGTAAAGAATGCGGGAA
AGCCTTTAGACAGCACTCACAGCTGACTGTACACCAGCGAATCCACACTGGTGAGAAACCCTACGAGTGTAAGGAATGCGGAAAGGGCTT
TATTCACAGCTCAGAAGTTACTCGACATCAAAGAATTCATTCTGGGGAGAAACCCTATGAGTGTAAGGAATGTGGGAAGGCCTTCAGACA
GCACGCACAGCTCACACGACATCAGAGAGTCCATACTGGCGACAGACCCTATGAATGTAAGGACTGCGGGAAGGCATTTAGTCGTAGCTC
ATACCTCATTCAACATCAAAGAATTCATACAGGTGACAAACCCTACGAATGTAAGGAATGTGGGAAGGCCTTTATTCGTGTTTCACAACT
GACTCATCATCAGCGAATTCACACTTGTGAGAAACCCTATGAATGCAGGGAGTGTGGAATGGCCTTTATTCGTAGTTCACAACTTACCGA
ACATCAGAGAATTCATCCTGGTATCAAACCTTACGAATGTAGAGAGTGTGGGCAGGCATTTATTCTTGGCTCACAACTCATTGAACACTA
CAGAATTCATACTGGTTAGAAAGCCTTGAGTGTAAGGGATAAAGATAAGCCTTTATGTGGAGTTCACATCTGGCTCAGTACTAGGTAATT
TTTAATGTAGTGTAATTAATGTCAGAAAACACCTGTCACTTCCATCATAGAACATCAGAAAACTCACACCCAAAGAAAATTAAATAAATG

>8583_8583_9_AXL-ZNF565_AXL_chr19_41762516_ENST00000593513_ZNF565_chr19_36686058_ENST00000392173_length(amino acids)=1032AA_BP=578
MNKTSSFSCEAHNAKGVTTSRTATITVLPQQPRNLHLVSRQPTELEVAWTPGLSGIYPLTHCTLQAVLSNDGMGIQAGEPDPPEEPLTSQ
ASVPPHQLRLGSLHPHTPYHIRVACTSSQGPSSWTHWLPVETPEGVPLGPPENISATRNGSQAFVHWQEPRAPLQGTLLGYRLAYQGQDT
PEVLMDIGLRQEVTLELQGDGSVSNLTVCVAAYTAAGDGPWSLPVPLEAWRPGQAQPVHQLVKEPSTPAFSWPWWYVLLGAVVAAACVLI
LALFLVHRRKKETRYGEVFEPTVERGELVVRYRVRKSYSRRTTEATLNSLGISEELKEKLRDVMVDRHKVALGKTLGEGEFGAVMEGQLN
QDDSILKVAVKTMKIAICTRSELEDFLSEAVCMKEFDHPNVMRLIGVCFQGSERESFPAPVVILPFMKHGDLHSFLLYSRLGDQPVYLPT
QMLVKFMADIASGMEYLSTKRFIHRDLAARNCMLNENMSVCVADFGLSKKIYNGDYYRQGRIAKMPVKWIAIESLADRVYTSKSDVGLVT
FRDVAIEFSLEEWKCLEPAQRDLYREVTLENFGHLASLGLSISKPDVVSLLEQGKEPWMIANDVTGPWCPDLESRCEKFLQKDIFEIGAF
NWEIMESLKCSDLEGSDFRADWECEGQFERQVNEECYFKQVNVTYGHMPVFQHHTSHTVRQSRETGEKLMECHECGKAFSRGSHLIQHQK
IHTGEKPFGCKECGKAFSRASHLVQHQRIHTGEKPYDCKDCGKAFGRTSELILHQRLHTGVKPYECKECGKTFRQHSQLILHQRTHTGEK
PYVCKDCGKAFIRGSQLTVHRRIHTGARPYECKECGKAFRQHSQLTVHQRIHTGEKPYECKECGKGFIHSSEVTRHQRIHSGEKPYECKE
CGKAFRQHAQLTRHQRVHTGDRPYECKDCGKAFSRSSYLIQHQRIHTGDKPYECKECGKAFIRVSQLTHHQRIHTCEKPYECRECGMAFI

--------------------------------------------------------------

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Fusion Gene PPI Analysis for AXL-ZNF565


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with
HgeneAXLchr19:41762516chr19:36686058ENST00000301178+182026_92732.0895.0GAS6
HgeneAXLchr19:41762516chr19:36686058ENST00000359092+171926_92723.0886.0GAS6


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for AXL-ZNF565


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for AXL-ZNF565


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource