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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:SPTB-RAB15 (FusionGDB2 ID:86161)

Fusion Gene Summary for SPTB-RAB15

check button Fusion gene summary
Fusion gene informationFusion gene name: SPTB-RAB15
Fusion gene ID: 86161
HgeneTgene
Gene symbol

SPTB

RAB15

Gene ID

6710

376267

Gene namespectrin beta, erythrocyticRAB15, member RAS oncogene family
SynonymsEL3|HS2|HSPTB1|SPH2-
Cytomap

14q23.3

14q23.3

Type of geneprotein-codingprotein-coding
Descriptionspectrin beta chain, erythrocyticSp betabeta-I spectrinmembrane cytoskeletal proteinspectrin beta Tandilspectrin beta chain, erythrocyteras-related protein Rab-15RAB15, member RAS onocogene familyRas-related protein Rab-15 isoform AN1Ras-related protein Rab-15 isoform AN2Ras-related protein Rab-15 isoform AN3
Modification date2020031320200313
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000389720, ENST00000389721, 
ENST00000389722, ENST00000542895, 
ENST00000556626, ENST00000342835, 
ENST00000426039, ENST00000436278, 
ENST00000267512, ENST00000533601, 
Fusion gene scores* DoF score3 X 3 X 2=183 X 2 X 2=12
# samples 32
** MAII scorelog2(3/18*10)=0.736965594166206
effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs).
DoF>8 and MAII>0		log2(2/12*10)=0.736965594166206
effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs).
DoF>8 and MAII>0
Context

PubMed: SPTB [Title/Abstract] AND RAB15 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointSPTB(65263275)-RAB15(65415451), # samples:2
Anticipated loss of major functional domain due to fusion event.SPTB-RAB15 seems lost the major protein functional domain in Hgene partner, which is a essential gene due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check buttonFusion gene breakpoints across SPTB (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across RAB15 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4LUADTCGA-55-8205-01ASPTBchr14

65263275

-RAB15chr14

65415451

-


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Fusion Gene ORF analysis for SPTB-RAB15

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-3UTRENST00000389720ENST00000426039SPTBchr14

65263275

-RAB15chr14

65415451

-
5CDS-3UTRENST00000389720ENST00000436278SPTBchr14

65263275

-RAB15chr14

65415451

-
5CDS-3UTRENST00000389721ENST00000426039SPTBchr14

65263275

-RAB15chr14

65415451

-
5CDS-3UTRENST00000389721ENST00000436278SPTBchr14

65263275

-RAB15chr14

65415451

-
5CDS-3UTRENST00000389722ENST00000426039SPTBchr14

65263275

-RAB15chr14

65415451

-
5CDS-3UTRENST00000389722ENST00000436278SPTBchr14

65263275

-RAB15chr14

65415451

-
5CDS-3UTRENST00000542895ENST00000426039SPTBchr14

65263275

-RAB15chr14

65415451

-
5CDS-3UTRENST00000542895ENST00000436278SPTBchr14

65263275

-RAB15chr14

65415451

-
5CDS-3UTRENST00000556626ENST00000426039SPTBchr14

65263275

-RAB15chr14

65415451

-
5CDS-3UTRENST00000556626ENST00000436278SPTBchr14

65263275

-RAB15chr14

65415451

-
Frame-shiftENST00000389720ENST00000267512SPTBchr14

65263275

-RAB15chr14

65415451

-
Frame-shiftENST00000389721ENST00000267512SPTBchr14

65263275

-RAB15chr14

65415451

-
Frame-shiftENST00000389722ENST00000267512SPTBchr14

65263275

-RAB15chr14

65415451

-
Frame-shiftENST00000542895ENST00000267512SPTBchr14

65263275

-RAB15chr14

65415451

-
Frame-shiftENST00000556626ENST00000267512SPTBchr14

65263275

-RAB15chr14

65415451

-
In-frameENST00000389720ENST00000533601SPTBchr14

65263275

-RAB15chr14

65415451

-
In-frameENST00000389721ENST00000533601SPTBchr14

65263275

-RAB15chr14

65415451

-
In-frameENST00000389722ENST00000533601SPTBchr14

65263275

-RAB15chr14

65415451

-
In-frameENST00000542895ENST00000533601SPTBchr14

65263275

-RAB15chr14

65415451

-
In-frameENST00000556626ENST00000533601SPTBchr14

65263275

-RAB15chr14

65415451

-
intron-3CDSENST00000342835ENST00000267512SPTBchr14

65263275

-RAB15chr14

65415451

-
intron-3CDSENST00000342835ENST00000533601SPTBchr14

65263275

-RAB15chr14

65415451

-
intron-3UTRENST00000342835ENST00000426039SPTBchr14

65263275

-RAB15chr14

65415451

-
intron-3UTRENST00000342835ENST00000436278SPTBchr14

65263275

-RAB15chr14

65415451

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000389722SPTBchr1465263275-ENST00000533601RAB15chr1465415451-41581395541619521
ENST00000556626SPTBchr1465263275-ENST00000533601RAB15chr1465415451-424714841431708521
ENST00000389721SPTBchr1465263275-ENST00000533601RAB15chr1465415451-41371374331598521
ENST00000542895SPTBchr1465263275-ENST00000533601RAB15chr1465415451-42011438971662521
ENST00000389720SPTBchr1465263275-ENST00000533601RAB15chr1465415451-4104134101565521

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000389722ENST00000533601SPTBchr1465263275-RAB15chr1465415451-0.0044398120.99556017
ENST00000556626ENST00000533601SPTBchr1465263275-RAB15chr1465415451-0.0046611430.9953388
ENST00000389721ENST00000533601SPTBchr1465263275-RAB15chr1465415451-0.0044937820.99550617
ENST00000542895ENST00000533601SPTBchr1465263275-RAB15chr1465415451-0.0044017760.99559826
ENST00000389720ENST00000533601SPTBchr1465263275-RAB15chr1465415451-0.0043142110.9956858

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Fusion Genomic Features for SPTB-RAB15


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for SPTB-RAB15


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr14:65263275/chr14:65415451)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneSPTBchr14:65263275chr14:65415451ENST00000389720-1030173_2784472107.0DomainCalponin-homology (CH) 2
HgeneSPTBchr14:65263275chr14:65415451ENST00000389720-103054_1584472107.0DomainCalponin-homology (CH) 1
HgeneSPTBchr14:65263275chr14:65415451ENST00000389721-1031173_2784472138.0DomainCalponin-homology (CH) 2
HgeneSPTBchr14:65263275chr14:65415451ENST00000389721-103154_1584472138.0DomainCalponin-homology (CH) 1
HgeneSPTBchr14:65263275chr14:65415451ENST00000389722-1035173_2784472329.0DomainCalponin-homology (CH) 2
HgeneSPTBchr14:65263275chr14:65415451ENST00000389722-103554_1584472329.0DomainCalponin-homology (CH) 1
HgeneSPTBchr14:65263275chr14:65415451ENST00000542895-1132173_2784472138.0DomainCalponin-homology (CH) 2
HgeneSPTBchr14:65263275chr14:65415451ENST00000542895-113254_1584472138.0DomainCalponin-homology (CH) 1
HgeneSPTBchr14:65263275chr14:65415451ENST00000556626-1136173_2784472329.0DomainCalponin-homology (CH) 2
HgeneSPTBchr14:65263275chr14:65415451ENST00000556626-113654_1584472329.0DomainCalponin-homology (CH) 1
HgeneSPTBchr14:65263275chr14:65415451ENST00000389720-10302_2754472107.0RegionNote=Actin-binding
HgeneSPTBchr14:65263275chr14:65415451ENST00000389721-10312_2754472138.0RegionNote=Actin-binding
HgeneSPTBchr14:65263275chr14:65415451ENST00000389722-10352_2754472329.0RegionNote=Actin-binding
HgeneSPTBchr14:65263275chr14:65415451ENST00000542895-11322_2754472138.0RegionNote=Actin-binding
HgeneSPTBchr14:65263275chr14:65415451ENST00000556626-11362_2754472329.0RegionNote=Actin-binding
HgeneSPTBchr14:65263275chr14:65415451ENST00000389720-1030303_4114472107.0RepeatSpectrin 1
HgeneSPTBchr14:65263275chr14:65415451ENST00000389721-1031303_4114472138.0RepeatSpectrin 1
HgeneSPTBchr14:65263275chr14:65415451ENST00000389722-1035303_4114472329.0RepeatSpectrin 1
HgeneSPTBchr14:65263275chr14:65415451ENST00000542895-1132303_4114472138.0RepeatSpectrin 1
HgeneSPTBchr14:65263275chr14:65415451ENST00000556626-1136303_4114472329.0RepeatSpectrin 1

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneSPTBchr14:65263275chr14:65415451ENST00000389720-10301062_11654472107.0RepeatSpectrin 8
HgeneSPTBchr14:65263275chr14:65415451ENST00000389720-10301170_12574472107.0RepeatSpectrin 9
HgeneSPTBchr14:65263275chr14:65415451ENST00000389720-10301275_13754472107.0RepeatSpectrin 10
HgeneSPTBchr14:65263275chr14:65415451ENST00000389720-10301389_14654472107.0RepeatSpectrin 11
HgeneSPTBchr14:65263275chr14:65415451ENST00000389720-10301481_15824472107.0RepeatSpectrin 12
HgeneSPTBchr14:65263275chr14:65415451ENST00000389720-10301585_16884472107.0RepeatSpectrin 13
HgeneSPTBchr14:65263275chr14:65415451ENST00000389720-10301690_17934472107.0RepeatSpectrin 14
HgeneSPTBchr14:65263275chr14:65415451ENST00000389720-10301797_18994472107.0RepeatSpectrin 15
HgeneSPTBchr14:65263275chr14:65415451ENST00000389720-10301906_20064472107.0RepeatSpectrin 16
HgeneSPTBchr14:65263275chr14:65415451ENST00000389720-10302013_20754472107.0RepeatSpectrin 17
HgeneSPTBchr14:65263275chr14:65415451ENST00000389720-1030423_5254472107.0RepeatSpectrin 2
HgeneSPTBchr14:65263275chr14:65415451ENST00000389720-1030529_6354472107.0RepeatSpectrin 3
HgeneSPTBchr14:65263275chr14:65415451ENST00000389720-1030638_7414472107.0RepeatSpectrin 4
HgeneSPTBchr14:65263275chr14:65415451ENST00000389720-1030744_8464472107.0RepeatSpectrin 5
HgeneSPTBchr14:65263275chr14:65415451ENST00000389720-1030851_9504472107.0RepeatSpectrin 6
HgeneSPTBchr14:65263275chr14:65415451ENST00000389720-1030956_10584472107.0RepeatSpectrin 7
HgeneSPTBchr14:65263275chr14:65415451ENST00000389721-10311062_11654472138.0RepeatSpectrin 8
HgeneSPTBchr14:65263275chr14:65415451ENST00000389721-10311170_12574472138.0RepeatSpectrin 9
HgeneSPTBchr14:65263275chr14:65415451ENST00000389721-10311275_13754472138.0RepeatSpectrin 10
HgeneSPTBchr14:65263275chr14:65415451ENST00000389721-10311389_14654472138.0RepeatSpectrin 11
HgeneSPTBchr14:65263275chr14:65415451ENST00000389721-10311481_15824472138.0RepeatSpectrin 12
HgeneSPTBchr14:65263275chr14:65415451ENST00000389721-10311585_16884472138.0RepeatSpectrin 13
HgeneSPTBchr14:65263275chr14:65415451ENST00000389721-10311690_17934472138.0RepeatSpectrin 14
HgeneSPTBchr14:65263275chr14:65415451ENST00000389721-10311797_18994472138.0RepeatSpectrin 15
HgeneSPTBchr14:65263275chr14:65415451ENST00000389721-10311906_20064472138.0RepeatSpectrin 16
HgeneSPTBchr14:65263275chr14:65415451ENST00000389721-10312013_20754472138.0RepeatSpectrin 17
HgeneSPTBchr14:65263275chr14:65415451ENST00000389721-1031423_5254472138.0RepeatSpectrin 2
HgeneSPTBchr14:65263275chr14:65415451ENST00000389721-1031529_6354472138.0RepeatSpectrin 3
HgeneSPTBchr14:65263275chr14:65415451ENST00000389721-1031638_7414472138.0RepeatSpectrin 4
HgeneSPTBchr14:65263275chr14:65415451ENST00000389721-1031744_8464472138.0RepeatSpectrin 5
HgeneSPTBchr14:65263275chr14:65415451ENST00000389721-1031851_9504472138.0RepeatSpectrin 6
HgeneSPTBchr14:65263275chr14:65415451ENST00000389721-1031956_10584472138.0RepeatSpectrin 7
HgeneSPTBchr14:65263275chr14:65415451ENST00000389722-10351062_11654472329.0RepeatSpectrin 8
HgeneSPTBchr14:65263275chr14:65415451ENST00000389722-10351170_12574472329.0RepeatSpectrin 9
HgeneSPTBchr14:65263275chr14:65415451ENST00000389722-10351275_13754472329.0RepeatSpectrin 10
HgeneSPTBchr14:65263275chr14:65415451ENST00000389722-10351389_14654472329.0RepeatSpectrin 11
HgeneSPTBchr14:65263275chr14:65415451ENST00000389722-10351481_15824472329.0RepeatSpectrin 12
HgeneSPTBchr14:65263275chr14:65415451ENST00000389722-10351585_16884472329.0RepeatSpectrin 13
HgeneSPTBchr14:65263275chr14:65415451ENST00000389722-10351690_17934472329.0RepeatSpectrin 14
HgeneSPTBchr14:65263275chr14:65415451ENST00000389722-10351797_18994472329.0RepeatSpectrin 15
HgeneSPTBchr14:65263275chr14:65415451ENST00000389722-10351906_20064472329.0RepeatSpectrin 16
HgeneSPTBchr14:65263275chr14:65415451ENST00000389722-10352013_20754472329.0RepeatSpectrin 17
HgeneSPTBchr14:65263275chr14:65415451ENST00000389722-1035423_5254472329.0RepeatSpectrin 2
HgeneSPTBchr14:65263275chr14:65415451ENST00000389722-1035529_6354472329.0RepeatSpectrin 3
HgeneSPTBchr14:65263275chr14:65415451ENST00000389722-1035638_7414472329.0RepeatSpectrin 4
HgeneSPTBchr14:65263275chr14:65415451ENST00000389722-1035744_8464472329.0RepeatSpectrin 5
HgeneSPTBchr14:65263275chr14:65415451ENST00000389722-1035851_9504472329.0RepeatSpectrin 6
HgeneSPTBchr14:65263275chr14:65415451ENST00000389722-1035956_10584472329.0RepeatSpectrin 7
HgeneSPTBchr14:65263275chr14:65415451ENST00000542895-11321062_11654472138.0RepeatSpectrin 8
HgeneSPTBchr14:65263275chr14:65415451ENST00000542895-11321170_12574472138.0RepeatSpectrin 9
HgeneSPTBchr14:65263275chr14:65415451ENST00000542895-11321275_13754472138.0RepeatSpectrin 10
HgeneSPTBchr14:65263275chr14:65415451ENST00000542895-11321389_14654472138.0RepeatSpectrin 11
HgeneSPTBchr14:65263275chr14:65415451ENST00000542895-11321481_15824472138.0RepeatSpectrin 12
HgeneSPTBchr14:65263275chr14:65415451ENST00000542895-11321585_16884472138.0RepeatSpectrin 13
HgeneSPTBchr14:65263275chr14:65415451ENST00000542895-11321690_17934472138.0RepeatSpectrin 14
HgeneSPTBchr14:65263275chr14:65415451ENST00000542895-11321797_18994472138.0RepeatSpectrin 15
HgeneSPTBchr14:65263275chr14:65415451ENST00000542895-11321906_20064472138.0RepeatSpectrin 16
HgeneSPTBchr14:65263275chr14:65415451ENST00000542895-11322013_20754472138.0RepeatSpectrin 17
HgeneSPTBchr14:65263275chr14:65415451ENST00000542895-1132423_5254472138.0RepeatSpectrin 2
HgeneSPTBchr14:65263275chr14:65415451ENST00000542895-1132529_6354472138.0RepeatSpectrin 3
HgeneSPTBchr14:65263275chr14:65415451ENST00000542895-1132638_7414472138.0RepeatSpectrin 4
HgeneSPTBchr14:65263275chr14:65415451ENST00000542895-1132744_8464472138.0RepeatSpectrin 5
HgeneSPTBchr14:65263275chr14:65415451ENST00000542895-1132851_9504472138.0RepeatSpectrin 6
HgeneSPTBchr14:65263275chr14:65415451ENST00000542895-1132956_10584472138.0RepeatSpectrin 7
HgeneSPTBchr14:65263275chr14:65415451ENST00000556626-11361062_11654472329.0RepeatSpectrin 8
HgeneSPTBchr14:65263275chr14:65415451ENST00000556626-11361170_12574472329.0RepeatSpectrin 9
HgeneSPTBchr14:65263275chr14:65415451ENST00000556626-11361275_13754472329.0RepeatSpectrin 10
HgeneSPTBchr14:65263275chr14:65415451ENST00000556626-11361389_14654472329.0RepeatSpectrin 11
HgeneSPTBchr14:65263275chr14:65415451ENST00000556626-11361481_15824472329.0RepeatSpectrin 12
HgeneSPTBchr14:65263275chr14:65415451ENST00000556626-11361585_16884472329.0RepeatSpectrin 13
HgeneSPTBchr14:65263275chr14:65415451ENST00000556626-11361690_17934472329.0RepeatSpectrin 14
HgeneSPTBchr14:65263275chr14:65415451ENST00000556626-11361797_18994472329.0RepeatSpectrin 15
HgeneSPTBchr14:65263275chr14:65415451ENST00000556626-11361906_20064472329.0RepeatSpectrin 16
HgeneSPTBchr14:65263275chr14:65415451ENST00000556626-11362013_20754472329.0RepeatSpectrin 17
HgeneSPTBchr14:65263275chr14:65415451ENST00000556626-1136423_5254472329.0RepeatSpectrin 2
HgeneSPTBchr14:65263275chr14:65415451ENST00000556626-1136529_6354472329.0RepeatSpectrin 3
HgeneSPTBchr14:65263275chr14:65415451ENST00000556626-1136638_7414472329.0RepeatSpectrin 4
HgeneSPTBchr14:65263275chr14:65415451ENST00000556626-1136744_8464472329.0RepeatSpectrin 5
HgeneSPTBchr14:65263275chr14:65415451ENST00000556626-1136851_9504472329.0RepeatSpectrin 6
HgeneSPTBchr14:65263275chr14:65415451ENST00000556626-1136956_10584472329.0RepeatSpectrin 7
TgeneRAB15chr14:65263275chr14:65415451ENST0000026751247121_124181209.0Nucleotide bindingGTP
TgeneRAB15chr14:65263275chr14:65415451ENST000002675124715_22181209.0Nucleotide bindingGTP
TgeneRAB15chr14:65263275chr14:65415451ENST000002675124763_67181209.0Nucleotide bindingGTP
TgeneRAB15chr14:65263275chr14:65415451ENST0000053360147121_124138213.0Nucleotide bindingGTP
TgeneRAB15chr14:65263275chr14:65415451ENST000005336014715_22138213.0Nucleotide bindingGTP
TgeneRAB15chr14:65263275chr14:65415451ENST000005336014763_67138213.0Nucleotide bindingGTP


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Fusion Gene Sequence for SPTB-RAB15


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>86161_86161_1_SPTB-RAB15_SPTB_chr14_65263275_ENST00000389720_RAB15_chr14_65415451_ENST00000533601_length(transcript)=4104nt_BP=1341nt
ATGACATCGGCCACAGAGTTTGAAAATGTGGGCAACCAGCCACCTTACAGCAGGATCAATGCCCGCTGGGACGCCCCAGACGACGAGCTG
GATAATGACAACAGCTCAGCCAGGCTCTTTGAGAGGTCCCGGATAAAGGCCTTGGCAGATGAGCGGGAAGTTGTTCAGAAAAAGACCTTC
ACGAAATGGGTGAACTCGCACCTGGCTCGAGTGTCCTGCCGCATCACCGATCTCTACAAGGACCTGCGGGATGGGCGCATGCTCATCAAG
CTGCTGGAGGTGCTCTCTGGAGAGATGCTGCCAAAGCCCACCAAGGGGAAGATGCGCATCCACTGCCTGGAGAATGTGGACAAGGCTCTC
CAGTTCCTCAAGGAGCAGCGTGTACACCTGGAGAACATGGGCTCCCACGACATTGTAGATGGCAACCACCGCCTGGTCCTGGGCCTCATC
TGGACCATCATCCTCCGCTTCCAGATTCAGGACATTGTGGTCCAAACTCAGGAAGGTCGTGAAACACGCTCAGCCAAGGATGCGTTGCTG
TTGTGGTGTCAGATGAAGACGGCAGGCTACCCTCATGTTAATGTCACCAACTTTACCTCCAGCTGGAAGGATGGCTTGGCCTTTAATGCC
CTGATACACAAGCACCGGCCCGACCTGATCGACTTTGATAAGCTGAAGGACTCCAATGCCCGGCACAACCTGGAGCACGCATTCAATGTG
GCTGAGCGCCAGCTGGGCATCATCCCGCTCCTCGACCCCGAAGATGTCTTTACGGAAAACCCTGATGAGAAATCCATCATCACCTATGTG
GTGGCCTTTTACCACTACTTCTCCAAGATGAAGGTGCTGGCAGTGGAGGGCAAGCGTGTCGGCAAGGTTATTGACCATGCCATTGAGACT
GAGAAGATGATTGAAAAGTACAGCGGGCTAGCCTCGGACCTGCTCACCTGGATCGAGCAGACCATCACTGTCCTGAACAGCCGCAAGTTT
GCCAACTCGCTGACGGGCGTCCAGCAGCAGCTGCAGGCCTTCAGCACCTACCGCACCGTGGAGAAGCCGCCCAAGTTTCAAGAGAAGGGG
AATCTGGAAGTTCTACTTTTTACCATCCAGTCCCGGATGAGAGCCAACAATCAGAAAGTGTACACACCCCACGATGGGAAACTAGTGTCT
GACATCAACAGGGCCTGGGAAAGCCTGGAGGAAGCTGAGTATCGGCGGGAGCTGGCCCTGAGAAATGAGCTCATTCGGCAGGAGAAGCTA
GAGCAACTGGCCCGGCGCTTTGACCGGAAGGCCGCAATGAGAGAGACCTGGCTCAGTGAAAACCAGCGCCTCGTGGCCCAGCTGGCGAAG
GAGTATGGCATGGACTTCTATGAAACAAGTGCCTGCACCAACCTCAACATTAAAGAGTCATTCACGCGTCTGACAGAGCTGGTGCTGCAG
GCCCATAGGAAGGAGCTGGAAGGCCTCCGGATGCGTGCCAGCAATGAGTTGGCACTGGCAGAGCTGGAGGAGGAGGAGGGCAAACCCGAG
GGCCCAGCGAACTCTTCGAAAACCTGCTGGTGCTGAGTCCTGTGTGGGGCACCCCACACGACACCCCTCTTCCCTCAGGAGGCCCGTGGG
CAGACAGGGGAGCCGGGGCTTTGCCCTGCTGCTGTCCTCTCGTGTGATGACCCTATTGAGTATCAGTAGCCACTACTCCCCCTGCCTGGC
CCTGAGAGCGGCTCTGCTGTCATCTCAAGCAGCCCCTGTCCCCAGCCCGTCCACCCTGGAGTGGTCTTCTTCAGCCTGTTTCCCCAGCCA
CAGGCCTGCTACGACCCCCACGATGTGCCGCAAGCACTGTCTCACCATCCCGCACCCACCAGACAACAGCCAGGGCTGGAGTCCAGGCCA
CTTTCAGCTGCTCCTTTCTCCGTGCATCGTGTCTCTTCTCTGCTTTTTCTCTCTTCCCCCACTTCTCTTTCTCTGACCCCTCCCCTCCGG
TGCGTTTCGTATCAAAGCTCCTCAAACCCCGTCCCCCGTGTGTCCTGCTGTGTGCAGCTCGCTCTTTCCTTCCTTCCTAAGCTATCCAAG
GGGATGGACCCAGGCTCGTGGGGAGGTTCCACCCTTGGATCCAGGAAGAACCCTCCACCCTGCCTCGTGGGTGGGCCAAAGGCTACAGGG
TGCTTCTTCCTCTTCCCCCACCCCCACTGTCCCTCATGTGCCATGGGCCTGCCTCCCCAGTGACCTGCGAAAGTGGAGCATCGAGGTAGG
AGGGAAACGGCAACCAGGGAGTCCTCGAGCCTGGGGCTGCCCTACCTCTACCCATTCCCCGACCAGAGCTTTGCCCTTGCTTGGCTGCCC
GCCTGCCTCTTTGGGGAACTGAGCTCAGAGGCAGGTGCTTCAGAGAAGGAAACAAAATGAGGGGTGGCAGGGATAAAAAGTCACCTCCAT
TCTCTACCTCCCATGCAGCATGAACACAATTTCTCTCCACCTGGCTCCCAAATTTAAAGATGTGGACCAAGGCCTGTGGGTACTCCAGGG
GCAAGGAGAGCCCTGGGGTCAGTGACACTGTCAGGCCAACCATGCACTCCACAAAGGGGAGCATTTGGAAATGAAGGACTAGCTCCTATG
TATCAGGTTAAGAGCAAGGGAGAGCTGGCCAGGGACAGCAGTTTGCACAGCAGAGGGGAATGTAGCAACAGCAGGGCCTCCTAGGCCCCA
TCTTCCATTTCTTAGGTAAGAAGAGCATTTCCTCAGACTCCCAGGCGGAGGACTGAGCCTAGCCTTCAGCAACCAAGGTTCTCCTGGGAC
CCAAAGTTTATGGGAGAAGGGCAAAGACTTCATGGGAAGAGAGAAGGAAGGCCCTGGGTAGAAACGCTTGGTGCTGTTCTCTTTGGCCTT
TAAGACAAAGCGCTCATCTTGCCCTCTACCTCCTGATAGGCTTGAGGGTTTGCCAACCACACTGTGGCTACAGGTGGAGGGAAGAGGACT
CCTTCCTCCAGAGTGCTATGTTCAGGAAGTTTCTTTAACCCCATATGGCCCAAGAGTAGCTCGTAGGAGGCCCTTTAAAGACGGAACAAG
TAATTTACCAGTTCTACTGGGGTTCCTGCCCACCGTCCCAAGGTGGGCGAGGCCTAGGAAGAGGGTCATTCTTAAGCCACACATTAGCTG
CACTGCGTGGCTGCAGCCAAAACAAAGAACTGGGTGTTGAGTATTCATCAACTAAGAACCAAAATCCAGGGCACTCATATGTGAAGGATA
AGAACCTCACTTCCTTACTCCTCCAAAAAGAAGTGGGGAAAGAACCATCAAACCTTTCCTCCTGACTTACCAAACCAGGAAAACAGCAGG
AGAGGGTGGCTCAGGACTTAGGGACAGGGTATAGCTTAGATGGTGGAAAGCAAAGGAGAGCAGGAAGTTGTAAATCACTGGCTAATGAGA
AAAGGAGACAGCTAACTCTAGGATGAAGCTGTGACTAGGCTGGAGTTGCTTCCTTGAAGATGGGACTCCTTGGGTATCAAGACCTATGCC
ACATCACACTGGGGCTAGGGAAGTAGGTGATGCCAGCCCTCAAGTCTGTCTTCAGCCAGGGACTTGAGAAGTTATATTGGGCAGTGGCTC
CAATCTGTGGACCAGTATTTCAGCTTTCCCTGAAGATCAGGCAGGGTGCCATTCATTGTCTTTCTCTCCTAGCCCCCTCAGGAAAGAAGG
ACTATATTTGTACTGTACCCTAGGGGTTCTGGAAGGGAAAACATGGAATCAGGATTCTATAGACTGATAGGCCCTATCCACAAGGGCCAT
GACTGGGAAAAGGTATGGGAGCAGAAGGAGAATTGGGATTTTAGGGTGCAGCTACGCTCACCCTAAACTTTTGGTGGCCTGGGGCATGTC
TTGAGGCCCAGACTGTTAACCAGGCTCTGCTGGCCTGTTTACTCGTCACCACCTCTGCACCTGCTGTCTTGAGACTCCATCCAGCCCCAG
GCACGCCACCTGCTCCTGAGCCTCCACTATCTCCCTGTGACGGGTGAACTTCGTGTACTGTGTCTCGGGTCCATATATGAATTGTGAGCA

>86161_86161_1_SPTB-RAB15_SPTB_chr14_65263275_ENST00000389720_RAB15_chr14_65415451_ENST00000533601_length(amino acids)=521AA_BP=446
MTSATEFENVGNQPPYSRINARWDAPDDELDNDNSSARLFERSRIKALADEREVVQKKTFTKWVNSHLARVSCRITDLYKDLRDGRMLIK
LLEVLSGEMLPKPTKGKMRIHCLENVDKALQFLKEQRVHLENMGSHDIVDGNHRLVLGLIWTIILRFQIQDIVVQTQEGRETRSAKDALL
LWCQMKTAGYPHVNVTNFTSSWKDGLAFNALIHKHRPDLIDFDKLKDSNARHNLEHAFNVAERQLGIIPLLDPEDVFTENPDEKSIITYV
VAFYHYFSKMKVLAVEGKRVGKVIDHAIETEKMIEKYSGLASDLLTWIEQTITVLNSRKFANSLTGVQQQLQAFSTYRTVEKPPKFQEKG
NLEVLLFTIQSRMRANNQKVYTPHDGKLVSDINRAWESLEEAEYRRELALRNELIRQEKLEQLARRFDRKAAMRETWLSENQRLVAQLAK

--------------------------------------------------------------
>86161_86161_2_SPTB-RAB15_SPTB_chr14_65263275_ENST00000389721_RAB15_chr14_65415451_ENST00000533601_length(transcript)=4137nt_BP=1374nt
TGAGGCAGGCGGAGCTGCTAAGAGCCTGCTGACATGACATCGGCCACAGAGTTTGAAAATGTGGGCAACCAGCCACCTTACAGCAGGATC
AATGCCCGCTGGGACGCCCCAGACGACGAGCTGGATAATGACAACAGCTCAGCCAGGCTCTTTGAGAGGTCCCGGATAAAGGCCTTGGCA
GATGAGCGGGAAGTTGTTCAGAAAAAGACCTTCACGAAATGGGTGAACTCGCACCTGGCTCGAGTGTCCTGCCGCATCACCGATCTCTAC
AAGGACCTGCGGGATGGGCGCATGCTCATCAAGCTGCTGGAGGTGCTCTCTGGAGAGATGCTGCCAAAGCCCACCAAGGGGAAGATGCGC
ATCCACTGCCTGGAGAATGTGGACAAGGCTCTCCAGTTCCTCAAGGAGCAGCGTGTACACCTGGAGAACATGGGCTCCCACGACATTGTA
GATGGCAACCACCGCCTGGTCCTGGGCCTCATCTGGACCATCATCCTCCGCTTCCAGATTCAGGACATTGTGGTCCAAACTCAGGAAGGT
CGTGAAACACGCTCAGCCAAGGATGCGTTGCTGTTGTGGTGTCAGATGAAGACGGCAGGCTACCCTCATGTTAATGTCACCAACTTTACC
TCCAGCTGGAAGGATGGCTTGGCCTTTAATGCCCTGATACACAAGCACCGGCCCGACCTGATCGACTTTGATAAGCTGAAGGACTCCAAT
GCCCGGCACAACCTGGAGCACGCATTCAATGTGGCTGAGCGCCAGCTGGGCATCATCCCGCTCCTCGACCCCGAAGATGTCTTTACGGAA
AACCCTGATGAGAAATCCATCATCACCTATGTGGTGGCCTTTTACCACTACTTCTCCAAGATGAAGGTGCTGGCAGTGGAGGGCAAGCGT
GTCGGCAAGGTTATTGACCATGCCATTGAGACTGAGAAGATGATTGAAAAGTACAGCGGGCTAGCCTCGGACCTGCTCACCTGGATCGAG
CAGACCATCACTGTCCTGAACAGCCGCAAGTTTGCCAACTCGCTGACGGGCGTCCAGCAGCAGCTGCAGGCCTTCAGCACCTACCGCACC
GTGGAGAAGCCGCCCAAGTTTCAAGAGAAGGGGAATCTGGAAGTTCTACTTTTTACCATCCAGTCCCGGATGAGAGCCAACAATCAGAAA
GTGTACACACCCCACGATGGGAAACTAGTGTCTGACATCAACAGGGCCTGGGAAAGCCTGGAGGAAGCTGAGTATCGGCGGGAGCTGGCC
CTGAGAAATGAGCTCATTCGGCAGGAGAAGCTAGAGCAACTGGCCCGGCGCTTTGACCGGAAGGCCGCAATGAGAGAGACCTGGCTCAGT
GAAAACCAGCGCCTCGTGGCCCAGCTGGCGAAGGAGTATGGCATGGACTTCTATGAAACAAGTGCCTGCACCAACCTCAACATTAAAGAG
TCATTCACGCGTCTGACAGAGCTGGTGCTGCAGGCCCATAGGAAGGAGCTGGAAGGCCTCCGGATGCGTGCCAGCAATGAGTTGGCACTG
GCAGAGCTGGAGGAGGAGGAGGGCAAACCCGAGGGCCCAGCGAACTCTTCGAAAACCTGCTGGTGCTGAGTCCTGTGTGGGGCACCCCAC
ACGACACCCCTCTTCCCTCAGGAGGCCCGTGGGCAGACAGGGGAGCCGGGGCTTTGCCCTGCTGCTGTCCTCTCGTGTGATGACCCTATT
GAGTATCAGTAGCCACTACTCCCCCTGCCTGGCCCTGAGAGCGGCTCTGCTGTCATCTCAAGCAGCCCCTGTCCCCAGCCCGTCCACCCT
GGAGTGGTCTTCTTCAGCCTGTTTCCCCAGCCACAGGCCTGCTACGACCCCCACGATGTGCCGCAAGCACTGTCTCACCATCCCGCACCC
ACCAGACAACAGCCAGGGCTGGAGTCCAGGCCACTTTCAGCTGCTCCTTTCTCCGTGCATCGTGTCTCTTCTCTGCTTTTTCTCTCTTCC
CCCACTTCTCTTTCTCTGACCCCTCCCCTCCGGTGCGTTTCGTATCAAAGCTCCTCAAACCCCGTCCCCCGTGTGTCCTGCTGTGTGCAG
CTCGCTCTTTCCTTCCTTCCTAAGCTATCCAAGGGGATGGACCCAGGCTCGTGGGGAGGTTCCACCCTTGGATCCAGGAAGAACCCTCCA
CCCTGCCTCGTGGGTGGGCCAAAGGCTACAGGGTGCTTCTTCCTCTTCCCCCACCCCCACTGTCCCTCATGTGCCATGGGCCTGCCTCCC
CAGTGACCTGCGAAAGTGGAGCATCGAGGTAGGAGGGAAACGGCAACCAGGGAGTCCTCGAGCCTGGGGCTGCCCTACCTCTACCCATTC
CCCGACCAGAGCTTTGCCCTTGCTTGGCTGCCCGCCTGCCTCTTTGGGGAACTGAGCTCAGAGGCAGGTGCTTCAGAGAAGGAAACAAAA
TGAGGGGTGGCAGGGATAAAAAGTCACCTCCATTCTCTACCTCCCATGCAGCATGAACACAATTTCTCTCCACCTGGCTCCCAAATTTAA
AGATGTGGACCAAGGCCTGTGGGTACTCCAGGGGCAAGGAGAGCCCTGGGGTCAGTGACACTGTCAGGCCAACCATGCACTCCACAAAGG
GGAGCATTTGGAAATGAAGGACTAGCTCCTATGTATCAGGTTAAGAGCAAGGGAGAGCTGGCCAGGGACAGCAGTTTGCACAGCAGAGGG
GAATGTAGCAACAGCAGGGCCTCCTAGGCCCCATCTTCCATTTCTTAGGTAAGAAGAGCATTTCCTCAGACTCCCAGGCGGAGGACTGAG
CCTAGCCTTCAGCAACCAAGGTTCTCCTGGGACCCAAAGTTTATGGGAGAAGGGCAAAGACTTCATGGGAAGAGAGAAGGAAGGCCCTGG
GTAGAAACGCTTGGTGCTGTTCTCTTTGGCCTTTAAGACAAAGCGCTCATCTTGCCCTCTACCTCCTGATAGGCTTGAGGGTTTGCCAAC
CACACTGTGGCTACAGGTGGAGGGAAGAGGACTCCTTCCTCCAGAGTGCTATGTTCAGGAAGTTTCTTTAACCCCATATGGCCCAAGAGT
AGCTCGTAGGAGGCCCTTTAAAGACGGAACAAGTAATTTACCAGTTCTACTGGGGTTCCTGCCCACCGTCCCAAGGTGGGCGAGGCCTAG
GAAGAGGGTCATTCTTAAGCCACACATTAGCTGCACTGCGTGGCTGCAGCCAAAACAAAGAACTGGGTGTTGAGTATTCATCAACTAAGA
ACCAAAATCCAGGGCACTCATATGTGAAGGATAAGAACCTCACTTCCTTACTCCTCCAAAAAGAAGTGGGGAAAGAACCATCAAACCTTT
CCTCCTGACTTACCAAACCAGGAAAACAGCAGGAGAGGGTGGCTCAGGACTTAGGGACAGGGTATAGCTTAGATGGTGGAAAGCAAAGGA
GAGCAGGAAGTTGTAAATCACTGGCTAATGAGAAAAGGAGACAGCTAACTCTAGGATGAAGCTGTGACTAGGCTGGAGTTGCTTCCTTGA
AGATGGGACTCCTTGGGTATCAAGACCTATGCCACATCACACTGGGGCTAGGGAAGTAGGTGATGCCAGCCCTCAAGTCTGTCTTCAGCC
AGGGACTTGAGAAGTTATATTGGGCAGTGGCTCCAATCTGTGGACCAGTATTTCAGCTTTCCCTGAAGATCAGGCAGGGTGCCATTCATT
GTCTTTCTCTCCTAGCCCCCTCAGGAAAGAAGGACTATATTTGTACTGTACCCTAGGGGTTCTGGAAGGGAAAACATGGAATCAGGATTC
TATAGACTGATAGGCCCTATCCACAAGGGCCATGACTGGGAAAAGGTATGGGAGCAGAAGGAGAATTGGGATTTTAGGGTGCAGCTACGC
TCACCCTAAACTTTTGGTGGCCTGGGGCATGTCTTGAGGCCCAGACTGTTAACCAGGCTCTGCTGGCCTGTTTACTCGTCACCACCTCTG
CACCTGCTGTCTTGAGACTCCATCCAGCCCCAGGCACGCCACCTGCTCCTGAGCCTCCACTATCTCCCTGTGACGGGTGAACTTCGTGTA

>86161_86161_2_SPTB-RAB15_SPTB_chr14_65263275_ENST00000389721_RAB15_chr14_65415451_ENST00000533601_length(amino acids)=521AA_BP=446
MTSATEFENVGNQPPYSRINARWDAPDDELDNDNSSARLFERSRIKALADEREVVQKKTFTKWVNSHLARVSCRITDLYKDLRDGRMLIK
LLEVLSGEMLPKPTKGKMRIHCLENVDKALQFLKEQRVHLENMGSHDIVDGNHRLVLGLIWTIILRFQIQDIVVQTQEGRETRSAKDALL
LWCQMKTAGYPHVNVTNFTSSWKDGLAFNALIHKHRPDLIDFDKLKDSNARHNLEHAFNVAERQLGIIPLLDPEDVFTENPDEKSIITYV
VAFYHYFSKMKVLAVEGKRVGKVIDHAIETEKMIEKYSGLASDLLTWIEQTITVLNSRKFANSLTGVQQQLQAFSTYRTVEKPPKFQEKG
NLEVLLFTIQSRMRANNQKVYTPHDGKLVSDINRAWESLEEAEYRRELALRNELIRQEKLEQLARRFDRKAAMRETWLSENQRLVAQLAK

--------------------------------------------------------------
>86161_86161_3_SPTB-RAB15_SPTB_chr14_65263275_ENST00000389722_RAB15_chr14_65415451_ENST00000533601_length(transcript)=4158nt_BP=1395nt
CAGGGATCCTTCCATGAAGACTGAGGCAGGCGGAGCTGCTAAGAGCCTGCTGACATGACATCGGCCACAGAGTTTGAAAATGTGGGCAAC
CAGCCACCTTACAGCAGGATCAATGCCCGCTGGGACGCCCCAGACGACGAGCTGGATAATGACAACAGCTCAGCCAGGCTCTTTGAGAGG
TCCCGGATAAAGGCCTTGGCAGATGAGCGGGAAGTTGTTCAGAAAAAGACCTTCACGAAATGGGTGAACTCGCACCTGGCTCGAGTGTCC
TGCCGCATCACCGATCTCTACAAGGACCTGCGGGATGGGCGCATGCTCATCAAGCTGCTGGAGGTGCTCTCTGGAGAGATGCTGCCAAAG
CCCACCAAGGGGAAGATGCGCATCCACTGCCTGGAGAATGTGGACAAGGCTCTCCAGTTCCTCAAGGAGCAGCGTGTACACCTGGAGAAC
ATGGGCTCCCACGACATTGTAGATGGCAACCACCGCCTGGTCCTGGGCCTCATCTGGACCATCATCCTCCGCTTCCAGATTCAGGACATT
GTGGTCCAAACTCAGGAAGGTCGTGAAACACGCTCAGCCAAGGATGCGTTGCTGTTGTGGTGTCAGATGAAGACGGCAGGCTACCCTCAT
GTTAATGTCACCAACTTTACCTCCAGCTGGAAGGATGGCTTGGCCTTTAATGCCCTGATACACAAGCACCGGCCCGACCTGATCGACTTT
GATAAGCTGAAGGACTCCAATGCCCGGCACAACCTGGAGCACGCATTCAATGTGGCTGAGCGCCAGCTGGGCATCATCCCGCTCCTCGAC
CCCGAAGATGTCTTTACGGAAAACCCTGATGAGAAATCCATCATCACCTATGTGGTGGCCTTTTACCACTACTTCTCCAAGATGAAGGTG
CTGGCAGTGGAGGGCAAGCGTGTCGGCAAGGTTATTGACCATGCCATTGAGACTGAGAAGATGATTGAAAAGTACAGCGGGCTAGCCTCG
GACCTGCTCACCTGGATCGAGCAGACCATCACTGTCCTGAACAGCCGCAAGTTTGCCAACTCGCTGACGGGCGTCCAGCAGCAGCTGCAG
GCCTTCAGCACCTACCGCACCGTGGAGAAGCCGCCCAAGTTTCAAGAGAAGGGGAATCTGGAAGTTCTACTTTTTACCATCCAGTCCCGG
ATGAGAGCCAACAATCAGAAAGTGTACACACCCCACGATGGGAAACTAGTGTCTGACATCAACAGGGCCTGGGAAAGCCTGGAGGAAGCT
GAGTATCGGCGGGAGCTGGCCCTGAGAAATGAGCTCATTCGGCAGGAGAAGCTAGAGCAACTGGCCCGGCGCTTTGACCGGAAGGCCGCA
ATGAGAGAGACCTGGCTCAGTGAAAACCAGCGCCTCGTGGCCCAGCTGGCGAAGGAGTATGGCATGGACTTCTATGAAACAAGTGCCTGC
ACCAACCTCAACATTAAAGAGTCATTCACGCGTCTGACAGAGCTGGTGCTGCAGGCCCATAGGAAGGAGCTGGAAGGCCTCCGGATGCGT
GCCAGCAATGAGTTGGCACTGGCAGAGCTGGAGGAGGAGGAGGGCAAACCCGAGGGCCCAGCGAACTCTTCGAAAACCTGCTGGTGCTGA
GTCCTGTGTGGGGCACCCCACACGACACCCCTCTTCCCTCAGGAGGCCCGTGGGCAGACAGGGGAGCCGGGGCTTTGCCCTGCTGCTGTC
CTCTCGTGTGATGACCCTATTGAGTATCAGTAGCCACTACTCCCCCTGCCTGGCCCTGAGAGCGGCTCTGCTGTCATCTCAAGCAGCCCC
TGTCCCCAGCCCGTCCACCCTGGAGTGGTCTTCTTCAGCCTGTTTCCCCAGCCACAGGCCTGCTACGACCCCCACGATGTGCCGCAAGCA
CTGTCTCACCATCCCGCACCCACCAGACAACAGCCAGGGCTGGAGTCCAGGCCACTTTCAGCTGCTCCTTTCTCCGTGCATCGTGTCTCT
TCTCTGCTTTTTCTCTCTTCCCCCACTTCTCTTTCTCTGACCCCTCCCCTCCGGTGCGTTTCGTATCAAAGCTCCTCAAACCCCGTCCCC
CGTGTGTCCTGCTGTGTGCAGCTCGCTCTTTCCTTCCTTCCTAAGCTATCCAAGGGGATGGACCCAGGCTCGTGGGGAGGTTCCACCCTT
GGATCCAGGAAGAACCCTCCACCCTGCCTCGTGGGTGGGCCAAAGGCTACAGGGTGCTTCTTCCTCTTCCCCCACCCCCACTGTCCCTCA
TGTGCCATGGGCCTGCCTCCCCAGTGACCTGCGAAAGTGGAGCATCGAGGTAGGAGGGAAACGGCAACCAGGGAGTCCTCGAGCCTGGGG
CTGCCCTACCTCTACCCATTCCCCGACCAGAGCTTTGCCCTTGCTTGGCTGCCCGCCTGCCTCTTTGGGGAACTGAGCTCAGAGGCAGGT
GCTTCAGAGAAGGAAACAAAATGAGGGGTGGCAGGGATAAAAAGTCACCTCCATTCTCTACCTCCCATGCAGCATGAACACAATTTCTCT
CCACCTGGCTCCCAAATTTAAAGATGTGGACCAAGGCCTGTGGGTACTCCAGGGGCAAGGAGAGCCCTGGGGTCAGTGACACTGTCAGGC
CAACCATGCACTCCACAAAGGGGAGCATTTGGAAATGAAGGACTAGCTCCTATGTATCAGGTTAAGAGCAAGGGAGAGCTGGCCAGGGAC
AGCAGTTTGCACAGCAGAGGGGAATGTAGCAACAGCAGGGCCTCCTAGGCCCCATCTTCCATTTCTTAGGTAAGAAGAGCATTTCCTCAG
ACTCCCAGGCGGAGGACTGAGCCTAGCCTTCAGCAACCAAGGTTCTCCTGGGACCCAAAGTTTATGGGAGAAGGGCAAAGACTTCATGGG
AAGAGAGAAGGAAGGCCCTGGGTAGAAACGCTTGGTGCTGTTCTCTTTGGCCTTTAAGACAAAGCGCTCATCTTGCCCTCTACCTCCTGA
TAGGCTTGAGGGTTTGCCAACCACACTGTGGCTACAGGTGGAGGGAAGAGGACTCCTTCCTCCAGAGTGCTATGTTCAGGAAGTTTCTTT
AACCCCATATGGCCCAAGAGTAGCTCGTAGGAGGCCCTTTAAAGACGGAACAAGTAATTTACCAGTTCTACTGGGGTTCCTGCCCACCGT
CCCAAGGTGGGCGAGGCCTAGGAAGAGGGTCATTCTTAAGCCACACATTAGCTGCACTGCGTGGCTGCAGCCAAAACAAAGAACTGGGTG
TTGAGTATTCATCAACTAAGAACCAAAATCCAGGGCACTCATATGTGAAGGATAAGAACCTCACTTCCTTACTCCTCCAAAAAGAAGTGG
GGAAAGAACCATCAAACCTTTCCTCCTGACTTACCAAACCAGGAAAACAGCAGGAGAGGGTGGCTCAGGACTTAGGGACAGGGTATAGCT
TAGATGGTGGAAAGCAAAGGAGAGCAGGAAGTTGTAAATCACTGGCTAATGAGAAAAGGAGACAGCTAACTCTAGGATGAAGCTGTGACT
AGGCTGGAGTTGCTTCCTTGAAGATGGGACTCCTTGGGTATCAAGACCTATGCCACATCACACTGGGGCTAGGGAAGTAGGTGATGCCAG
CCCTCAAGTCTGTCTTCAGCCAGGGACTTGAGAAGTTATATTGGGCAGTGGCTCCAATCTGTGGACCAGTATTTCAGCTTTCCCTGAAGA
TCAGGCAGGGTGCCATTCATTGTCTTTCTCTCCTAGCCCCCTCAGGAAAGAAGGACTATATTTGTACTGTACCCTAGGGGTTCTGGAAGG
GAAAACATGGAATCAGGATTCTATAGACTGATAGGCCCTATCCACAAGGGCCATGACTGGGAAAAGGTATGGGAGCAGAAGGAGAATTGG
GATTTTAGGGTGCAGCTACGCTCACCCTAAACTTTTGGTGGCCTGGGGCATGTCTTGAGGCCCAGACTGTTAACCAGGCTCTGCTGGCCT
GTTTACTCGTCACCACCTCTGCACCTGCTGTCTTGAGACTCCATCCAGCCCCAGGCACGCCACCTGCTCCTGAGCCTCCACTATCTCCCT
GTGACGGGTGAACTTCGTGTACTGTGTCTCGGGTCCATATATGAATTGTGAGCAGGGTTCATCTATTTTAAACACAGATGTTTACAAAAT

>86161_86161_3_SPTB-RAB15_SPTB_chr14_65263275_ENST00000389722_RAB15_chr14_65415451_ENST00000533601_length(amino acids)=521AA_BP=446
MTSATEFENVGNQPPYSRINARWDAPDDELDNDNSSARLFERSRIKALADEREVVQKKTFTKWVNSHLARVSCRITDLYKDLRDGRMLIK
LLEVLSGEMLPKPTKGKMRIHCLENVDKALQFLKEQRVHLENMGSHDIVDGNHRLVLGLIWTIILRFQIQDIVVQTQEGRETRSAKDALL
LWCQMKTAGYPHVNVTNFTSSWKDGLAFNALIHKHRPDLIDFDKLKDSNARHNLEHAFNVAERQLGIIPLLDPEDVFTENPDEKSIITYV
VAFYHYFSKMKVLAVEGKRVGKVIDHAIETEKMIEKYSGLASDLLTWIEQTITVLNSRKFANSLTGVQQQLQAFSTYRTVEKPPKFQEKG
NLEVLLFTIQSRMRANNQKVYTPHDGKLVSDINRAWESLEEAEYRRELALRNELIRQEKLEQLARRFDRKAAMRETWLSENQRLVAQLAK

--------------------------------------------------------------
>86161_86161_4_SPTB-RAB15_SPTB_chr14_65263275_ENST00000542895_RAB15_chr14_65415451_ENST00000533601_length(transcript)=4201nt_BP=1438nt
CGCCACCCCCGGGCTCGGGGTGGCCCCCGCTTCAGTCCCAGGGCAGGGATCCTTCCATGAAGACTGAGGCAGGCGGAGCTGCTAAGAGCC
TGCTGACATGACATCGGCCACAGAGTTTGAAAATGTGGGCAACCAGCCACCTTACAGCAGGATCAATGCCCGCTGGGACGCCCCAGACGA
CGAGCTGGATAATGACAACAGCTCAGCCAGGCTCTTTGAGAGGTCCCGGATAAAGGCCTTGGCAGATGAGCGGGAAGTTGTTCAGAAAAA
GACCTTCACGAAATGGGTGAACTCGCACCTGGCTCGAGTGTCCTGCCGCATCACCGATCTCTACAAGGACCTGCGGGATGGGCGCATGCT
CATCAAGCTGCTGGAGGTGCTCTCTGGAGAGATGCTGCCAAAGCCCACCAAGGGGAAGATGCGCATCCACTGCCTGGAGAATGTGGACAA
GGCTCTCCAGTTCCTCAAGGAGCAGCGTGTACACCTGGAGAACATGGGCTCCCACGACATTGTAGATGGCAACCACCGCCTGGTCCTGGG
CCTCATCTGGACCATCATCCTCCGCTTCCAGATTCAGGACATTGTGGTCCAAACTCAGGAAGGTCGTGAAACACGCTCAGCCAAGGATGC
GTTGCTGTTGTGGTGTCAGATGAAGACGGCAGGCTACCCTCATGTTAATGTCACCAACTTTACCTCCAGCTGGAAGGATGGCTTGGCCTT
TAATGCCCTGATACACAAGCACCGGCCCGACCTGATCGACTTTGATAAGCTGAAGGACTCCAATGCCCGGCACAACCTGGAGCACGCATT
CAATGTGGCTGAGCGCCAGCTGGGCATCATCCCGCTCCTCGACCCCGAAGATGTCTTTACGGAAAACCCTGATGAGAAATCCATCATCAC
CTATGTGGTGGCCTTTTACCACTACTTCTCCAAGATGAAGGTGCTGGCAGTGGAGGGCAAGCGTGTCGGCAAGGTTATTGACCATGCCAT
TGAGACTGAGAAGATGATTGAAAAGTACAGCGGGCTAGCCTCGGACCTGCTCACCTGGATCGAGCAGACCATCACTGTCCTGAACAGCCG
CAAGTTTGCCAACTCGCTGACGGGCGTCCAGCAGCAGCTGCAGGCCTTCAGCACCTACCGCACCGTGGAGAAGCCGCCCAAGTTTCAAGA
GAAGGGGAATCTGGAAGTTCTACTTTTTACCATCCAGTCCCGGATGAGAGCCAACAATCAGAAAGTGTACACACCCCACGATGGGAAACT
AGTGTCTGACATCAACAGGGCCTGGGAAAGCCTGGAGGAAGCTGAGTATCGGCGGGAGCTGGCCCTGAGAAATGAGCTCATTCGGCAGGA
GAAGCTAGAGCAACTGGCCCGGCGCTTTGACCGGAAGGCCGCAATGAGAGAGACCTGGCTCAGTGAAAACCAGCGCCTCGTGGCCCAGCT
GGCGAAGGAGTATGGCATGGACTTCTATGAAACAAGTGCCTGCACCAACCTCAACATTAAAGAGTCATTCACGCGTCTGACAGAGCTGGT
GCTGCAGGCCCATAGGAAGGAGCTGGAAGGCCTCCGGATGCGTGCCAGCAATGAGTTGGCACTGGCAGAGCTGGAGGAGGAGGAGGGCAA
ACCCGAGGGCCCAGCGAACTCTTCGAAAACCTGCTGGTGCTGAGTCCTGTGTGGGGCACCCCACACGACACCCCTCTTCCCTCAGGAGGC
CCGTGGGCAGACAGGGGAGCCGGGGCTTTGCCCTGCTGCTGTCCTCTCGTGTGATGACCCTATTGAGTATCAGTAGCCACTACTCCCCCT
GCCTGGCCCTGAGAGCGGCTCTGCTGTCATCTCAAGCAGCCCCTGTCCCCAGCCCGTCCACCCTGGAGTGGTCTTCTTCAGCCTGTTTCC
CCAGCCACAGGCCTGCTACGACCCCCACGATGTGCCGCAAGCACTGTCTCACCATCCCGCACCCACCAGACAACAGCCAGGGCTGGAGTC
CAGGCCACTTTCAGCTGCTCCTTTCTCCGTGCATCGTGTCTCTTCTCTGCTTTTTCTCTCTTCCCCCACTTCTCTTTCTCTGACCCCTCC
CCTCCGGTGCGTTTCGTATCAAAGCTCCTCAAACCCCGTCCCCCGTGTGTCCTGCTGTGTGCAGCTCGCTCTTTCCTTCCTTCCTAAGCT
ATCCAAGGGGATGGACCCAGGCTCGTGGGGAGGTTCCACCCTTGGATCCAGGAAGAACCCTCCACCCTGCCTCGTGGGTGGGCCAAAGGC
TACAGGGTGCTTCTTCCTCTTCCCCCACCCCCACTGTCCCTCATGTGCCATGGGCCTGCCTCCCCAGTGACCTGCGAAAGTGGAGCATCG
AGGTAGGAGGGAAACGGCAACCAGGGAGTCCTCGAGCCTGGGGCTGCCCTACCTCTACCCATTCCCCGACCAGAGCTTTGCCCTTGCTTG
GCTGCCCGCCTGCCTCTTTGGGGAACTGAGCTCAGAGGCAGGTGCTTCAGAGAAGGAAACAAAATGAGGGGTGGCAGGGATAAAAAGTCA
CCTCCATTCTCTACCTCCCATGCAGCATGAACACAATTTCTCTCCACCTGGCTCCCAAATTTAAAGATGTGGACCAAGGCCTGTGGGTAC
TCCAGGGGCAAGGAGAGCCCTGGGGTCAGTGACACTGTCAGGCCAACCATGCACTCCACAAAGGGGAGCATTTGGAAATGAAGGACTAGC
TCCTATGTATCAGGTTAAGAGCAAGGGAGAGCTGGCCAGGGACAGCAGTTTGCACAGCAGAGGGGAATGTAGCAACAGCAGGGCCTCCTA
GGCCCCATCTTCCATTTCTTAGGTAAGAAGAGCATTTCCTCAGACTCCCAGGCGGAGGACTGAGCCTAGCCTTCAGCAACCAAGGTTCTC
CTGGGACCCAAAGTTTATGGGAGAAGGGCAAAGACTTCATGGGAAGAGAGAAGGAAGGCCCTGGGTAGAAACGCTTGGTGCTGTTCTCTT
TGGCCTTTAAGACAAAGCGCTCATCTTGCCCTCTACCTCCTGATAGGCTTGAGGGTTTGCCAACCACACTGTGGCTACAGGTGGAGGGAA
GAGGACTCCTTCCTCCAGAGTGCTATGTTCAGGAAGTTTCTTTAACCCCATATGGCCCAAGAGTAGCTCGTAGGAGGCCCTTTAAAGACG
GAACAAGTAATTTACCAGTTCTACTGGGGTTCCTGCCCACCGTCCCAAGGTGGGCGAGGCCTAGGAAGAGGGTCATTCTTAAGCCACACA
TTAGCTGCACTGCGTGGCTGCAGCCAAAACAAAGAACTGGGTGTTGAGTATTCATCAACTAAGAACCAAAATCCAGGGCACTCATATGTG
AAGGATAAGAACCTCACTTCCTTACTCCTCCAAAAAGAAGTGGGGAAAGAACCATCAAACCTTTCCTCCTGACTTACCAAACCAGGAAAA
CAGCAGGAGAGGGTGGCTCAGGACTTAGGGACAGGGTATAGCTTAGATGGTGGAAAGCAAAGGAGAGCAGGAAGTTGTAAATCACTGGCT
AATGAGAAAAGGAGACAGCTAACTCTAGGATGAAGCTGTGACTAGGCTGGAGTTGCTTCCTTGAAGATGGGACTCCTTGGGTATCAAGAC
CTATGCCACATCACACTGGGGCTAGGGAAGTAGGTGATGCCAGCCCTCAAGTCTGTCTTCAGCCAGGGACTTGAGAAGTTATATTGGGCA
GTGGCTCCAATCTGTGGACCAGTATTTCAGCTTTCCCTGAAGATCAGGCAGGGTGCCATTCATTGTCTTTCTCTCCTAGCCCCCTCAGGA
AAGAAGGACTATATTTGTACTGTACCCTAGGGGTTCTGGAAGGGAAAACATGGAATCAGGATTCTATAGACTGATAGGCCCTATCCACAA
GGGCCATGACTGGGAAAAGGTATGGGAGCAGAAGGAGAATTGGGATTTTAGGGTGCAGCTACGCTCACCCTAAACTTTTGGTGGCCTGGG
GCATGTCTTGAGGCCCAGACTGTTAACCAGGCTCTGCTGGCCTGTTTACTCGTCACCACCTCTGCACCTGCTGTCTTGAGACTCCATCCA
GCCCCAGGCACGCCACCTGCTCCTGAGCCTCCACTATCTCCCTGTGACGGGTGAACTTCGTGTACTGTGTCTCGGGTCCATATATGAATT

>86161_86161_4_SPTB-RAB15_SPTB_chr14_65263275_ENST00000542895_RAB15_chr14_65415451_ENST00000533601_length(amino acids)=521AA_BP=446
MTSATEFENVGNQPPYSRINARWDAPDDELDNDNSSARLFERSRIKALADEREVVQKKTFTKWVNSHLARVSCRITDLYKDLRDGRMLIK
LLEVLSGEMLPKPTKGKMRIHCLENVDKALQFLKEQRVHLENMGSHDIVDGNHRLVLGLIWTIILRFQIQDIVVQTQEGRETRSAKDALL
LWCQMKTAGYPHVNVTNFTSSWKDGLAFNALIHKHRPDLIDFDKLKDSNARHNLEHAFNVAERQLGIIPLLDPEDVFTENPDEKSIITYV
VAFYHYFSKMKVLAVEGKRVGKVIDHAIETEKMIEKYSGLASDLLTWIEQTITVLNSRKFANSLTGVQQQLQAFSTYRTVEKPPKFQEKG
NLEVLLFTIQSRMRANNQKVYTPHDGKLVSDINRAWESLEEAEYRRELALRNELIRQEKLEQLARRFDRKAAMRETWLSENQRLVAQLAK

--------------------------------------------------------------
>86161_86161_5_SPTB-RAB15_SPTB_chr14_65263275_ENST00000556626_RAB15_chr14_65415451_ENST00000533601_length(transcript)=4247nt_BP=1484nt
GTGCCAGGAGCCCCGCGCTGCCCTCCTCCCCCTGCGCCGCCGCCGCCGCCACCCCCGGGCTCGGGGTGGCCCCCGCTTCAGTCCCAGGGC
AGGGATCCTTCCATGAAGACTGAGGCAGGCGGAGCTGCTAAGAGCCTGCTGACATGACATCGGCCACAGAGTTTGAAAATGTGGGCAACC
AGCCACCTTACAGCAGGATCAATGCCCGCTGGGACGCCCCAGACGACGAGCTGGATAATGACAACAGCTCAGCCAGGCTCTTTGAGAGGT
CCCGGATAAAGGCCTTGGCAGATGAGCGGGAAGTTGTTCAGAAAAAGACCTTCACGAAATGGGTGAACTCGCACCTGGCTCGAGTGTCCT
GCCGCATCACCGATCTCTACAAGGACCTGCGGGATGGGCGCATGCTCATCAAGCTGCTGGAGGTGCTCTCTGGAGAGATGCTGCCAAAGC
CCACCAAGGGGAAGATGCGCATCCACTGCCTGGAGAATGTGGACAAGGCTCTCCAGTTCCTCAAGGAGCAGCGTGTACACCTGGAGAACA
TGGGCTCCCACGACATTGTAGATGGCAACCACCGCCTGGTCCTGGGCCTCATCTGGACCATCATCCTCCGCTTCCAGATTCAGGACATTG
TGGTCCAAACTCAGGAAGGTCGTGAAACACGCTCAGCCAAGGATGCGTTGCTGTTGTGGTGTCAGATGAAGACGGCAGGCTACCCTCATG
TTAATGTCACCAACTTTACCTCCAGCTGGAAGGATGGCTTGGCCTTTAATGCCCTGATACACAAGCACCGGCCCGACCTGATCGACTTTG
ATAAGCTGAAGGACTCCAATGCCCGGCACAACCTGGAGCACGCATTCAATGTGGCTGAGCGCCAGCTGGGCATCATCCCGCTCCTCGACC
CCGAAGATGTCTTTACGGAAAACCCTGATGAGAAATCCATCATCACCTATGTGGTGGCCTTTTACCACTACTTCTCCAAGATGAAGGTGC
TGGCAGTGGAGGGCAAGCGTGTCGGCAAGGTTATTGACCATGCCATTGAGACTGAGAAGATGATTGAAAAGTACAGCGGGCTAGCCTCGG
ACCTGCTCACCTGGATCGAGCAGACCATCACTGTCCTGAACAGCCGCAAGTTTGCCAACTCGCTGACGGGCGTCCAGCAGCAGCTGCAGG
CCTTCAGCACCTACCGCACCGTGGAGAAGCCGCCCAAGTTTCAAGAGAAGGGGAATCTGGAAGTTCTACTTTTTACCATCCAGTCCCGGA
TGAGAGCCAACAATCAGAAAGTGTACACACCCCACGATGGGAAACTAGTGTCTGACATCAACAGGGCCTGGGAAAGCCTGGAGGAAGCTG
AGTATCGGCGGGAGCTGGCCCTGAGAAATGAGCTCATTCGGCAGGAGAAGCTAGAGCAACTGGCCCGGCGCTTTGACCGGAAGGCCGCAA
TGAGAGAGACCTGGCTCAGTGAAAACCAGCGCCTCGTGGCCCAGCTGGCGAAGGAGTATGGCATGGACTTCTATGAAACAAGTGCCTGCA
CCAACCTCAACATTAAAGAGTCATTCACGCGTCTGACAGAGCTGGTGCTGCAGGCCCATAGGAAGGAGCTGGAAGGCCTCCGGATGCGTG
CCAGCAATGAGTTGGCACTGGCAGAGCTGGAGGAGGAGGAGGGCAAACCCGAGGGCCCAGCGAACTCTTCGAAAACCTGCTGGTGCTGAG
TCCTGTGTGGGGCACCCCACACGACACCCCTCTTCCCTCAGGAGGCCCGTGGGCAGACAGGGGAGCCGGGGCTTTGCCCTGCTGCTGTCC
TCTCGTGTGATGACCCTATTGAGTATCAGTAGCCACTACTCCCCCTGCCTGGCCCTGAGAGCGGCTCTGCTGTCATCTCAAGCAGCCCCT
GTCCCCAGCCCGTCCACCCTGGAGTGGTCTTCTTCAGCCTGTTTCCCCAGCCACAGGCCTGCTACGACCCCCACGATGTGCCGCAAGCAC
TGTCTCACCATCCCGCACCCACCAGACAACAGCCAGGGCTGGAGTCCAGGCCACTTTCAGCTGCTCCTTTCTCCGTGCATCGTGTCTCTT
CTCTGCTTTTTCTCTCTTCCCCCACTTCTCTTTCTCTGACCCCTCCCCTCCGGTGCGTTTCGTATCAAAGCTCCTCAAACCCCGTCCCCC
GTGTGTCCTGCTGTGTGCAGCTCGCTCTTTCCTTCCTTCCTAAGCTATCCAAGGGGATGGACCCAGGCTCGTGGGGAGGTTCCACCCTTG
GATCCAGGAAGAACCCTCCACCCTGCCTCGTGGGTGGGCCAAAGGCTACAGGGTGCTTCTTCCTCTTCCCCCACCCCCACTGTCCCTCAT
GTGCCATGGGCCTGCCTCCCCAGTGACCTGCGAAAGTGGAGCATCGAGGTAGGAGGGAAACGGCAACCAGGGAGTCCTCGAGCCTGGGGC
TGCCCTACCTCTACCCATTCCCCGACCAGAGCTTTGCCCTTGCTTGGCTGCCCGCCTGCCTCTTTGGGGAACTGAGCTCAGAGGCAGGTG
CTTCAGAGAAGGAAACAAAATGAGGGGTGGCAGGGATAAAAAGTCACCTCCATTCTCTACCTCCCATGCAGCATGAACACAATTTCTCTC
CACCTGGCTCCCAAATTTAAAGATGTGGACCAAGGCCTGTGGGTACTCCAGGGGCAAGGAGAGCCCTGGGGTCAGTGACACTGTCAGGCC
AACCATGCACTCCACAAAGGGGAGCATTTGGAAATGAAGGACTAGCTCCTATGTATCAGGTTAAGAGCAAGGGAGAGCTGGCCAGGGACA
GCAGTTTGCACAGCAGAGGGGAATGTAGCAACAGCAGGGCCTCCTAGGCCCCATCTTCCATTTCTTAGGTAAGAAGAGCATTTCCTCAGA
CTCCCAGGCGGAGGACTGAGCCTAGCCTTCAGCAACCAAGGTTCTCCTGGGACCCAAAGTTTATGGGAGAAGGGCAAAGACTTCATGGGA
AGAGAGAAGGAAGGCCCTGGGTAGAAACGCTTGGTGCTGTTCTCTTTGGCCTTTAAGACAAAGCGCTCATCTTGCCCTCTACCTCCTGAT
AGGCTTGAGGGTTTGCCAACCACACTGTGGCTACAGGTGGAGGGAAGAGGACTCCTTCCTCCAGAGTGCTATGTTCAGGAAGTTTCTTTA
ACCCCATATGGCCCAAGAGTAGCTCGTAGGAGGCCCTTTAAAGACGGAACAAGTAATTTACCAGTTCTACTGGGGTTCCTGCCCACCGTC
CCAAGGTGGGCGAGGCCTAGGAAGAGGGTCATTCTTAAGCCACACATTAGCTGCACTGCGTGGCTGCAGCCAAAACAAAGAACTGGGTGT
TGAGTATTCATCAACTAAGAACCAAAATCCAGGGCACTCATATGTGAAGGATAAGAACCTCACTTCCTTACTCCTCCAAAAAGAAGTGGG
GAAAGAACCATCAAACCTTTCCTCCTGACTTACCAAACCAGGAAAACAGCAGGAGAGGGTGGCTCAGGACTTAGGGACAGGGTATAGCTT
AGATGGTGGAAAGCAAAGGAGAGCAGGAAGTTGTAAATCACTGGCTAATGAGAAAAGGAGACAGCTAACTCTAGGATGAAGCTGTGACTA
GGCTGGAGTTGCTTCCTTGAAGATGGGACTCCTTGGGTATCAAGACCTATGCCACATCACACTGGGGCTAGGGAAGTAGGTGATGCCAGC
CCTCAAGTCTGTCTTCAGCCAGGGACTTGAGAAGTTATATTGGGCAGTGGCTCCAATCTGTGGACCAGTATTTCAGCTTTCCCTGAAGAT
CAGGCAGGGTGCCATTCATTGTCTTTCTCTCCTAGCCCCCTCAGGAAAGAAGGACTATATTTGTACTGTACCCTAGGGGTTCTGGAAGGG
AAAACATGGAATCAGGATTCTATAGACTGATAGGCCCTATCCACAAGGGCCATGACTGGGAAAAGGTATGGGAGCAGAAGGAGAATTGGG
ATTTTAGGGTGCAGCTACGCTCACCCTAAACTTTTGGTGGCCTGGGGCATGTCTTGAGGCCCAGACTGTTAACCAGGCTCTGCTGGCCTG
TTTACTCGTCACCACCTCTGCACCTGCTGTCTTGAGACTCCATCCAGCCCCAGGCACGCCACCTGCTCCTGAGCCTCCACTATCTCCCTG
TGACGGGTGAACTTCGTGTACTGTGTCTCGGGTCCATATATGAATTGTGAGCAGGGTTCATCTATTTTAAACACAGATGTTTACAAAATA

>86161_86161_5_SPTB-RAB15_SPTB_chr14_65263275_ENST00000556626_RAB15_chr14_65415451_ENST00000533601_length(amino acids)=521AA_BP=446
MTSATEFENVGNQPPYSRINARWDAPDDELDNDNSSARLFERSRIKALADEREVVQKKTFTKWVNSHLARVSCRITDLYKDLRDGRMLIK
LLEVLSGEMLPKPTKGKMRIHCLENVDKALQFLKEQRVHLENMGSHDIVDGNHRLVLGLIWTIILRFQIQDIVVQTQEGRETRSAKDALL
LWCQMKTAGYPHVNVTNFTSSWKDGLAFNALIHKHRPDLIDFDKLKDSNARHNLEHAFNVAERQLGIIPLLDPEDVFTENPDEKSIITYV
VAFYHYFSKMKVLAVEGKRVGKVIDHAIETEKMIEKYSGLASDLLTWIEQTITVLNSRKFANSLTGVQQQLQAFSTYRTVEKPPKFQEKG
NLEVLLFTIQSRMRANNQKVYTPHDGKLVSDINRAWESLEEAEYRRELALRNELIRQEKLEQLARRFDRKAAMRETWLSENQRLVAQLAK

--------------------------------------------------------------

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Fusion Gene PPI Analysis for SPTB-RAB15


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for SPTB-RAB15


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for SPTB-RAB15


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource