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 | Fusion Gene Summary |
| Fusion Gene ORF analysis |
| Fusion Genomic Features |
| Fusion Protein Features |
| Fusion Gene Sequence |
| Fusion Gene PPI analysis |
| Related Drugs |
| Related Diseases |
Fusion gene:SRGAP1-TBC1D30 (FusionGDB2 ID:86350) |
Fusion Gene Summary for SRGAP1-TBC1D30 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: SRGAP1-TBC1D30 | Fusion gene ID: 86350 | Hgene | Tgene | Gene symbol | SRGAP1 | TBC1D30 | Gene ID | 57522 | 23329 |
| Gene name | SLIT-ROBO Rho GTPase activating protein 1 | TBC1 domain family member 30 | |
| Synonyms | ARHGAP13|NMTC2 | - | |
| Cytomap | 12q14.2 | 12q14.3 | |
| Type of gene | protein-coding | protein-coding | |
| Description | SLIT-ROBO Rho GTPase-activating protein 1rho GTPase-activating protein 13 | TBC1 domain family member 30 | |
| Modification date | 20200313 | 20200313 | |
| UniProtAcc | . | . | |
| Ensembl transtripts involved in fusion gene | ENST00000355086, ENST00000357825, ENST00000543397, | ENST00000456757, ENST00000539867, ENST00000229088, ENST00000542120, | |
| Fusion gene scores | * DoF score | 20 X 14 X 11=3080 | 14 X 11 X 8=1232 |
| # samples | 21 | 16 | |
| ** MAII score | log2(21/3080*10)=-3.87446911791614 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(16/1232*10)=-2.94485844580754 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: SRGAP1 [Title/Abstract] AND TBC1D30 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Most frequent breakpoint | SRGAP1(64410792)-TBC1D30(65258448), # samples:2 | ||
| Anticipated loss of major functional domain due to fusion event. | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Tgene | TBC1D30 | GO:0043547 | positive regulation of GTPase activity | 17646400 |
| Fusion gene breakpoints across SRGAP1 (5'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
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| Fusion gene breakpoints across TBC1D30 (3'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
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| Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Source | Disease | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| ChimerDB4 | CHOL | TCGA-W5-AA2X-01A | SRGAP1 | chr12 | 64410792 | + | TBC1D30 | chr12 | 65258448 | + |
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Fusion Gene ORF analysis for SRGAP1-TBC1D30 |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| 5CDS-intron | ENST00000355086 | ENST00000456757 | SRGAP1 | chr12 | 64410792 | + | TBC1D30 | chr12 | 65258448 | + |
| 5CDS-intron | ENST00000355086 | ENST00000539867 | SRGAP1 | chr12 | 64410792 | + | TBC1D30 | chr12 | 65258448 | + |
| 5CDS-intron | ENST00000357825 | ENST00000456757 | SRGAP1 | chr12 | 64410792 | + | TBC1D30 | chr12 | 65258448 | + |
| 5CDS-intron | ENST00000357825 | ENST00000539867 | SRGAP1 | chr12 | 64410792 | + | TBC1D30 | chr12 | 65258448 | + |
| 5CDS-intron | ENST00000543397 | ENST00000456757 | SRGAP1 | chr12 | 64410792 | + | TBC1D30 | chr12 | 65258448 | + |
| 5CDS-intron | ENST00000543397 | ENST00000539867 | SRGAP1 | chr12 | 64410792 | + | TBC1D30 | chr12 | 65258448 | + |
| In-frame | ENST00000355086 | ENST00000229088 | SRGAP1 | chr12 | 64410792 | + | TBC1D30 | chr12 | 65258448 | + |
| In-frame | ENST00000355086 | ENST00000542120 | SRGAP1 | chr12 | 64410792 | + | TBC1D30 | chr12 | 65258448 | + |
| In-frame | ENST00000357825 | ENST00000229088 | SRGAP1 | chr12 | 64410792 | + | TBC1D30 | chr12 | 65258448 | + |
| In-frame | ENST00000357825 | ENST00000542120 | SRGAP1 | chr12 | 64410792 | + | TBC1D30 | chr12 | 65258448 | + |
| In-frame | ENST00000543397 | ENST00000229088 | SRGAP1 | chr12 | 64410792 | + | TBC1D30 | chr12 | 65258448 | + |
| In-frame | ENST00000543397 | ENST00000542120 | SRGAP1 | chr12 | 64410792 | + | TBC1D30 | chr12 | 65258448 | + |
| ORFfinder result based on the fusion transcript sequence of in-frame fusion genes. |
| Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | Seq length (transcript) | BP loci (transcript) | Predicted start (transcript) | Predicted stop (transcript) | Seq length (amino acids) |
| ENST00000355086 | SRGAP1 | chr12 | 64410792 | + | ENST00000542120 | TBC1D30 | chr12 | 65258448 | + | 7505 | 1013 | 524 | 2260 | 578 |
| ENST00000355086 | SRGAP1 | chr12 | 64410792 | + | ENST00000229088 | TBC1D30 | chr12 | 65258448 | + | 4776 | 1013 | 524 | 2260 | 578 |
| ENST00000357825 | SRGAP1 | chr12 | 64410792 | + | ENST00000542120 | TBC1D30 | chr12 | 65258448 | + | 7037 | 545 | 56 | 1792 | 578 |
| ENST00000357825 | SRGAP1 | chr12 | 64410792 | + | ENST00000229088 | TBC1D30 | chr12 | 65258448 | + | 4308 | 545 | 56 | 1792 | 578 |
| ENST00000543397 | SRGAP1 | chr12 | 64410792 | + | ENST00000542120 | TBC1D30 | chr12 | 65258448 | + | 8336 | 1844 | 1400 | 3091 | 563 |
| ENST00000543397 | SRGAP1 | chr12 | 64410792 | + | ENST00000229088 | TBC1D30 | chr12 | 65258448 | + | 5607 | 1844 | 1400 | 3091 | 563 |
| DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated. |
| Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | No-coding score | Coding score |
| ENST00000355086 | ENST00000542120 | SRGAP1 | chr12 | 64410792 | + | TBC1D30 | chr12 | 65258448 | + | 0.000498136 | 0.9995018 |
| ENST00000355086 | ENST00000229088 | SRGAP1 | chr12 | 64410792 | + | TBC1D30 | chr12 | 65258448 | + | 0.001375471 | 0.99862456 |
| ENST00000357825 | ENST00000542120 | SRGAP1 | chr12 | 64410792 | + | TBC1D30 | chr12 | 65258448 | + | 0.000439764 | 0.9995602 |
| ENST00000357825 | ENST00000229088 | SRGAP1 | chr12 | 64410792 | + | TBC1D30 | chr12 | 65258448 | + | 0.001142642 | 0.9988574 |
| ENST00000543397 | ENST00000542120 | SRGAP1 | chr12 | 64410792 | + | TBC1D30 | chr12 | 65258448 | + | 0.000702475 | 0.9992975 |
| ENST00000543397 | ENST00000229088 | SRGAP1 | chr12 | 64410792 | + | TBC1D30 | chr12 | 65258448 | + | 0.001095926 | 0.9989041 |
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Fusion Genomic Features for SRGAP1-TBC1D30 |
| FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints. |
| Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | 1-p | p (fusion gene breakpoint) |
| SRGAP1 | chr12 | 64410792 | + | TBC1D30 | chr12 | 65258447 | + | 0.003032745 | 0.99696726 |
| SRGAP1 | chr12 | 64410792 | + | TBC1D30 | chr12 | 65258447 | + | 0.003032745 | 0.99696726 |
| Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page. |
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| Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page. |
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Fusion Protein Features for SRGAP1-TBC1D30 |
| Four levels of functional features of fusion genes Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr12:64410792/chr12:65258448) - FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels. - How to search 1. Put your fusion gene symbol. 2. Press the tab key until there will be shown the breakpoint information filled. 4. Go down and press 'Search' tab twice. 4. Go down to have the hyperlink of the search result. 5. Click the hyperlink. 6. See the FGviewer result for your fusion gene. |
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| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| . | . |
| FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}. | FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | SRGAP1 | chr12:64410792 | chr12:65258448 | ENST00000355086 | + | 4 | 22 | 351_390 | 163 | 1086.0 | Coiled coil | Ontology_term=ECO:0000255 |
| Hgene | SRGAP1 | chr12:64410792 | chr12:65258448 | ENST00000355086 | + | 4 | 22 | 956_985 | 163 | 1086.0 | Coiled coil | Ontology_term=ECO:0000255 |
| Hgene | SRGAP1 | chr12:64410792 | chr12:65258448 | ENST00000357825 | + | 4 | 22 | 351_390 | 163 | 1063.0 | Coiled coil | Ontology_term=ECO:0000255 |
| Hgene | SRGAP1 | chr12:64410792 | chr12:65258448 | ENST00000357825 | + | 4 | 22 | 956_985 | 163 | 1063.0 | Coiled coil | Ontology_term=ECO:0000255 |
| Hgene | SRGAP1 | chr12:64410792 | chr12:65258448 | ENST00000355086 | + | 4 | 22 | 1027_1032 | 163 | 1086.0 | Compositional bias | Note=Poly-Ser |
| Hgene | SRGAP1 | chr12:64410792 | chr12:65258448 | ENST00000355086 | + | 4 | 22 | 854_857 | 163 | 1086.0 | Compositional bias | Note=Poly-Pro |
| Hgene | SRGAP1 | chr12:64410792 | chr12:65258448 | ENST00000355086 | + | 4 | 22 | 909_912 | 163 | 1086.0 | Compositional bias | Note=Poly-Arg |
| Hgene | SRGAP1 | chr12:64410792 | chr12:65258448 | ENST00000357825 | + | 4 | 22 | 1027_1032 | 163 | 1063.0 | Compositional bias | Note=Poly-Ser |
| Hgene | SRGAP1 | chr12:64410792 | chr12:65258448 | ENST00000357825 | + | 4 | 22 | 854_857 | 163 | 1063.0 | Compositional bias | Note=Poly-Pro |
| Hgene | SRGAP1 | chr12:64410792 | chr12:65258448 | ENST00000357825 | + | 4 | 22 | 909_912 | 163 | 1063.0 | Compositional bias | Note=Poly-Arg |
| Hgene | SRGAP1 | chr12:64410792 | chr12:65258448 | ENST00000355086 | + | 4 | 22 | 19_314 | 163 | 1086.0 | Domain | F-BAR |
| Hgene | SRGAP1 | chr12:64410792 | chr12:65258448 | ENST00000355086 | + | 4 | 22 | 506_694 | 163 | 1086.0 | Domain | Rho-GAP |
| Hgene | SRGAP1 | chr12:64410792 | chr12:65258448 | ENST00000355086 | + | 4 | 22 | 743_802 | 163 | 1086.0 | Domain | SH3 |
| Hgene | SRGAP1 | chr12:64410792 | chr12:65258448 | ENST00000357825 | + | 4 | 22 | 19_314 | 163 | 1063.0 | Domain | F-BAR |
| Hgene | SRGAP1 | chr12:64410792 | chr12:65258448 | ENST00000357825 | + | 4 | 22 | 506_694 | 163 | 1063.0 | Domain | Rho-GAP |
| Hgene | SRGAP1 | chr12:64410792 | chr12:65258448 | ENST00000357825 | + | 4 | 22 | 743_802 | 163 | 1063.0 | Domain | SH3 |
| Tgene | TBC1D30 | chr12:64410792 | chr12:65258448 | ENST00000229088 | 8 | 13 | 249_457 | 509 | 925.0 | Domain | Rab-GAP TBC | |
| Tgene | TBC1D30 | chr12:64410792 | chr12:65258448 | ENST00000539867 | 7 | 12 | 249_457 | 346 | 762.0 | Domain | Rab-GAP TBC |
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Fusion Gene Sequence for SRGAP1-TBC1D30 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones. |
| >86350_86350_1_SRGAP1-TBC1D30_SRGAP1_chr12_64410792_ENST00000355086_TBC1D30_chr12_65258448_ENST00000229088_length(transcript)=4776nt_BP=1013nt CGGGACCCTTGAGCGCCGGAGCCGACAGCTGGAGGCAGGAAGGGAGGGTTGTGGCGCCCGAGCTGGGCGCGTTCCCAGCGCCTGCCCTCC GCCGCTGGCCCTGTCCCGGGCGCCCGGTGCGGGTCTCGAACAATGGTGCGGAGCGCCGGCGCGAGCCCCGCGCCCGCCCAGCGGCCGTAG AGGAAGTGGCCGGGCTCCCGGCGAGGTGGGCAGGGAGACGTCCCCCGCCACTCGCTGGCTGGAGTTTGCCTGCGCGTCCGGCCTCTCCCC CGGGGATCCCCTGGGATTACCGACGGAGCTCAATTTCGAGAGTATGGTGCCAGCGCCCGGGCTAATCTAGTCCTCTCTACTCGCTCTTTT TCCCCTCCTCCTCCTACTTCTCCTCTCCCTCCTCCCTTCCCTCGGGTCGGCGCTGCCTCTGGATTGCCTGCGTGTGGGAGTACAACTCTG CCTCTCCAAGGAGAACGGGTTGTGACCACTGAACAAAACTTGCCCATTGAAAGCAAACCCGGAACAGCTGGATAATGTCCACCCCGAGCC GATTCAAGAAGGACAAAGAGATCATAGCCGAGTATGAAAGTCAAGTCAAAGAAATTCGAGCTCAACTGGTAGAACAACAAAAATGCCTGG AGCAGCAAACGGAGATGCGAGTTCAGCTTCTCCAGGATCTGCAAGATTTCTTCCGAAAAAAAGCTGAAATTGAGACGGAATATTCCCGGA ATCTAGAGAAGTTAGCAGAAAGGTTCATGGCAAAAACAAGAAGCACTAAGGATCATCAACAATACAAGAAAGACCAGAACCTGTTGTCTC CAGTGAACTGCTGGTATTTGCTCCTGAACCAAGTAAGGAGAGAAAGCAAAGACCATGCAACCTTGAGTGACATCTATCTGAACAATGTGA TTATGCGGTTCATGCAGATAAGTGAGGATTCTACCAGGATGTTTAAAAAGAGCAAAGAGATTGCATTCCAACTTCATGAGGATTTAATGA AGGTTCTTAATGAGCTTTATACGACTGTTTATTCCATGGCTCCGTTCCCTTTCCCACAATTGGCAGAGTTGAGGGAAAAATACACCTACA ACATTACACCGTTCCCAGCCACAGTTAAACCCACCTCAGTTTCTGGACGACATAGTAAGGCCAGAGACAGTGATGAAGAGAATGACCCAG ACGATGAGGATGCTGTCGTTAATGCAGTGGGGTGTCTTGGACCTTTTAGTGGGTTCCTGGCTCCTGAACTGCAGAAGTACCAAAAACAAA TTAAAGAGCCAAATGAGGAGCAGAGTCTGAGATCTAATAACATTGCAGAGCTGAGTCCAGGAGCAATCAATTCCTGTCGAAGTGAATACC ATGCAGCTTTTAACAGTATGATGATGGAACGCATGACCACAGATATCAATGCACTGAAGCGGCAGTACTCTCGAATTAAAAAGAAGCAAC AGCAGCAGGTTCATCAGGTGTACATCAGGGCAGACAAAGGGCCAGTGACCAGCATTCTCCCGTCTCAGGTAAACAGTTCTCCAGTTATAA ACCACCTTCTTTTAGGAAAGAAGATGAAAATGACTAACAGAGCTGCCAAGAATGCTGTCATCCACATCCCTGGTCACACAGGAGGGAAAA TATCTCCTGTCCCCTACGAAGACCTTAAGACGAAGCTCAACTCCCCGTGGCGAACTCACATCCGAGTCCACAAAAAGAACATGCCAAGGA CCAAGAGTCATCCGGGCTGTGGGGACACCGTAGGGCTGATAGATGAGCAGAACGAGGCCAGCAAGACCAATGGGCTGGGGGCAGCAGAGG CATTCCCCTCTGGTTGTACAGCGACAGCTGGGAGAGAAGGCAGCAGCCCTGAAGGCAGTACCAGGAGGACGATCGAGGGGCAGTCTCCGG AGCCGGTGTTCGGAGATGCTGATGTGGATGTGTCTGCAGTTCAGGCGAAGTTGGGAGCCCTGGAACTGAACCAGAGGGATGCTGCAGCTG AAACTGAGCTCAGGGTGCACCCACCCTGCCAGCGGCACTGCCCAGAGCCGCCGAGTGCACCCGAAGAAAACAAAGCCACCAGCAAAGCTC CCCAAGGCAGCAACTCAAAAACCCCCATCTTTAGCCCTTTTCCCAGCGTCAAGCCCCTGCGGAAATCTGCTACTGCCAGGAACTTGGGAT TATATGGCCCTACAGAAAGAACCCCAACTGTGCACTTTCCTCAAATGAGTAGGAGCTTCAGCAAACCCGGCGGTGGAAACAGTGGCACTA AAAAACGATGATGTCTCCCCGAAACTTTGTATCTGGACTCACCTTTTCACAGTAGTATAAGGGTTGCAGCTGAATGGCTCTAAAAGAGTT TTATTTGTCCAGTGAAAATGAATAGGTTCAGGGATGAGCAACAGCCCATAAAAAATGGGAACTGGAAGTTTTATAATAGGAGTTAGAACA GGGCTGTTTTCCCAGCTACTTGCTAACTGACGAAGTGGATTCTTGTGGCAAAATAAATATTGTGGTTTTATAGTGTGAAGTTTTCCCAAT TTTTCATTGTGAGCTGTTTAAAAAAGACTATATCTAGATTGTTAACTCTCGTCCATCCTTCTGTTCTGGGGGCCTTCAGAGTCCCTGTGA CAGCACCCCCAAACCTTCCAGTTCTCTGGGTGTTACTAATACTCAAGCATGCACATACCAGCTTGCTAGGACAGAAACTGTAAAAAGAAA GTAAGTTTCTTCGTTACAAAAAACTTCCTGATTTTCCTTTTCATGCTTTACGGAGGGGATTGTGTCGTGTGAGATTTCCCACAGTACCAG TTTCAAATTTTTTTTTTATTCTTATGCTAAATCATAGGAGAAAAATCTAGATAGCCTTTCTTTAACTGTCTATTTCTACCTGCAAAATGA AGAAAACCTTTCATCTGTTGAAATTTCAATCGATAACCCAGCTGAAGATCTTATGCACAGGACACACTTGGCATATGCTTTACGCAGTTG CTCCGGACAGCTTGCTCGCGCCACTGAGCTTTTCCTGAGGTTTGTGTTCGCCTCTCAAGGAGAGCTTTGATCCTCAGTGGTACGGATGAC TTGATGGGCTCCATGCGGAGCCTGGCCTGCATCCCCCACCACACAGCTCACTCACCCACCAGCTCTAGACTGCAGACGCACAAGGCCTCT GCTCAGAAGCCAGAACACAGCACCTGTGACTCTGTTACTTGAATTTTGTGCTTTTTGATTGGAGTCCTTTGTTGAGTACTTTGTTAATTG AACACTGCCTTTCTCTGGAGAAGGCCCCAGTGCTTTCTAGCTCCCTCTCACTCCTGCCCTTTCTAGCTCTCTCTCACCCAGCGGGTCAGG GATAGCACCTCTTGTCTCCACTATGCAGATGGGAACTCTGAGCCACACAGAGGTGAAGTAGCACTTCAGTTACTCAAGGTCAGTACTCTC GGTATTCCAAGTGACTTAGCCACATTTCCTTCAGTGCAATAGGTGGGTTTAATGCTCTTTGTACACAGATGTATTGGCTACATAGCGTGT AAAAACCAAGACTGGGAAGCCATTCACTAAAATCCCTCCTGACTCAAAGGACCTGTCTCCAGATGGTACAGAGTCCCTTGATGGCATTTT ACAAAACCAGCTCTGACTTCCTTATCCTGAACAGGGAGTTTATTTTAAAAATGCTTCATGCACCTGTTATTTGGCTGAACAGAAGGCTCA CTCCTCAATCCCCTTCTCCTCGCCATCATTAGAGGAATAGACTCAGCCTTCATGTTTGTCTCTGGAAGACGATTGGCGATACTTGCAGGA ATATTGTTGATGCAGCCAATATTAATTTGAGCTAATGGATTGTTAATTCTGAAACGAAAACTGTAACTGTAGAGCAGGCTTTTACTATGA GAGGTACTACTTTTTATAATAGAGAATGTGGTTGTGTGGGCTTTTTTTGAACAGAAAACACAACAATGACCTATACCGTGAGAAAAGCCA TTTTATCTTCTTCGTGGTATTTTTACCCCCAAAGGAACTGAAGATGGAAAATATGACTAATAAGTTATTGCAGTTTTGGTCTTGAATTCT GTGCCATCTGAAGTTAGCATCCAGCTTCTTAAAAAGCAGCCACGCCTACAGCCTGTTTTTTGGGAAGGCTGTAGGTGGAGAGATGGGCTT ATTTTGCATACCACCCTCAGGGCCCAGAGACCCACTGCATTTTCCAAAGTTAAGCAAATGACACCATTTTCTTCCATCAGCTAAACTTTA CAGATAATAGTGTTTCCACCTCATATCCTTTTCTTTGCCCCTTCTCAAATGAGTCAGAATAGTCATGTTCCCCTTGAGGGATGTCTGACT TGAATGGAGAATTGTTCTTTCCTCTCTTGAATCAGCTCACTAGCTCCCTGATGGTCTGGGTTCAAGGAAATGGTTAATGAGGTAGAGGCC ACTTATACAAGTCCTTGGGATTGTACCATTGCTGTCCACAAACTTAGTATCAACAACACATGCTGTGCCCTGTGAACACTCTCCTCTCAC CTATTTCCAGGGTTGGTCTTCCTGAGAAGGGGATGGATGAGGTAACACACAGTTTGGGATACGTATCTGTTGAATGAATGAATAAGTGAA AGGATAATAGTCCTCTGAGGTAAAAATGGCCTTGTCAGAATTTTGAAAATCCAACAGATTCCTATTAAAGCACTCTGTGTACCAATAACA TGCATGCATTGTACCAAGTAATCACAATGTGAATTGGTCAATTTATGAGCCTTGCCTACTTTAGAAAATAAAGAAACCTGCAGTAGCCTC >86350_86350_1_SRGAP1-TBC1D30_SRGAP1_chr12_64410792_ENST00000355086_TBC1D30_chr12_65258448_ENST00000229088_length(amino acids)=578AA_BP=163 MSTPSRFKKDKEIIAEYESQVKEIRAQLVEQQKCLEQQTEMRVQLLQDLQDFFRKKAEIETEYSRNLEKLAERFMAKTRSTKDHQQYKKD QNLLSPVNCWYLLLNQVRRESKDHATLSDIYLNNVIMRFMQISEDSTRMFKKSKEIAFQLHEDLMKVLNELYTTVYSMAPFPFPQLAELR EKYTYNITPFPATVKPTSVSGRHSKARDSDEENDPDDEDAVVNAVGCLGPFSGFLAPELQKYQKQIKEPNEEQSLRSNNIAELSPGAINS CRSEYHAAFNSMMMERMTTDINALKRQYSRIKKKQQQQVHQVYIRADKGPVTSILPSQVNSSPVINHLLLGKKMKMTNRAAKNAVIHIPG HTGGKISPVPYEDLKTKLNSPWRTHIRVHKKNMPRTKSHPGCGDTVGLIDEQNEASKTNGLGAAEAFPSGCTATAGREGSSPEGSTRRTI EGQSPEPVFGDADVDVSAVQAKLGALELNQRDAAAETELRVHPPCQRHCPEPPSAPEENKATSKAPQGSNSKTPIFSPFPSVKPLRKSAT -------------------------------------------------------------- >86350_86350_2_SRGAP1-TBC1D30_SRGAP1_chr12_64410792_ENST00000355086_TBC1D30_chr12_65258448_ENST00000542120_length(transcript)=7505nt_BP=1013nt CGGGACCCTTGAGCGCCGGAGCCGACAGCTGGAGGCAGGAAGGGAGGGTTGTGGCGCCCGAGCTGGGCGCGTTCCCAGCGCCTGCCCTCC GCCGCTGGCCCTGTCCCGGGCGCCCGGTGCGGGTCTCGAACAATGGTGCGGAGCGCCGGCGCGAGCCCCGCGCCCGCCCAGCGGCCGTAG AGGAAGTGGCCGGGCTCCCGGCGAGGTGGGCAGGGAGACGTCCCCCGCCACTCGCTGGCTGGAGTTTGCCTGCGCGTCCGGCCTCTCCCC CGGGGATCCCCTGGGATTACCGACGGAGCTCAATTTCGAGAGTATGGTGCCAGCGCCCGGGCTAATCTAGTCCTCTCTACTCGCTCTTTT TCCCCTCCTCCTCCTACTTCTCCTCTCCCTCCTCCCTTCCCTCGGGTCGGCGCTGCCTCTGGATTGCCTGCGTGTGGGAGTACAACTCTG CCTCTCCAAGGAGAACGGGTTGTGACCACTGAACAAAACTTGCCCATTGAAAGCAAACCCGGAACAGCTGGATAATGTCCACCCCGAGCC GATTCAAGAAGGACAAAGAGATCATAGCCGAGTATGAAAGTCAAGTCAAAGAAATTCGAGCTCAACTGGTAGAACAACAAAAATGCCTGG AGCAGCAAACGGAGATGCGAGTTCAGCTTCTCCAGGATCTGCAAGATTTCTTCCGAAAAAAAGCTGAAATTGAGACGGAATATTCCCGGA ATCTAGAGAAGTTAGCAGAAAGGTTCATGGCAAAAACAAGAAGCACTAAGGATCATCAACAATACAAGAAAGACCAGAACCTGTTGTCTC CAGTGAACTGCTGGTATTTGCTCCTGAACCAAGTAAGGAGAGAAAGCAAAGACCATGCAACCTTGAGTGACATCTATCTGAACAATGTGA TTATGCGGTTCATGCAGATAAGTGAGGATTCTACCAGGATGTTTAAAAAGAGCAAAGAGATTGCATTCCAACTTCATGAGGATTTAATGA AGGTTCTTAATGAGCTTTATACGACTGTTTATTCCATGGCTCCGTTCCCTTTCCCACAATTGGCAGAGTTGAGGGAAAAATACACCTACA ACATTACACCGTTCCCAGCCACAGTTAAACCCACCTCAGTTTCTGGACGACATAGTAAGGCCAGAGACAGTGATGAAGAGAATGACCCAG ACGATGAGGATGCTGTCGTTAATGCAGTGGGGTGTCTTGGACCTTTTAGTGGGTTCCTGGCTCCTGAACTGCAGAAGTACCAAAAACAAA TTAAAGAGCCAAATGAGGAGCAGAGTCTGAGATCTAATAACATTGCAGAGCTGAGTCCAGGAGCAATCAATTCCTGTCGAAGTGAATACC ATGCAGCTTTTAACAGTATGATGATGGAACGCATGACCACAGATATCAATGCACTGAAGCGGCAGTACTCTCGAATTAAAAAGAAGCAAC AGCAGCAGGTTCATCAGGTGTACATCAGGGCAGACAAAGGGCCAGTGACCAGCATTCTCCCGTCTCAGGTAAACAGTTCTCCAGTTATAA ACCACCTTCTTTTAGGAAAGAAGATGAAAATGACTAACAGAGCTGCCAAGAATGCTGTCATCCACATCCCTGGTCACACAGGAGGGAAAA TATCTCCTGTCCCCTACGAAGACCTTAAGACGAAGCTCAACTCCCCGTGGCGAACTCACATCCGAGTCCACAAAAAGAACATGCCAAGGA CCAAGAGTCATCCGGGCTGTGGGGACACCGTAGGGCTGATAGATGAGCAGAACGAGGCCAGCAAGACCAATGGGCTGGGGGCAGCAGAGG CATTCCCCTCTGGTTGTACAGCGACAGCTGGGAGAGAAGGCAGCAGCCCTGAAGGCAGTACCAGGAGGACGATCGAGGGGCAGTCTCCGG AGCCGGTGTTCGGAGATGCTGATGTGGATGTGTCTGCAGTTCAGGCGAAGTTGGGAGCCCTGGAACTGAACCAGAGGGATGCTGCAGCTG AAACTGAGCTCAGGGTGCACCCACCCTGCCAGCGGCACTGCCCAGAGCCGCCGAGTGCACCCGAAGAAAACAAAGCCACCAGCAAAGCTC CCCAAGGCAGCAACTCAAAAACCCCCATCTTTAGCCCTTTTCCCAGCGTCAAGCCCCTGCGGAAATCTGCTACTGCCAGGAACTTGGGAT TATATGGCCCTACAGAAAGAACCCCAACTGTGCACTTTCCTCAAATGAGTAGGAGCTTCAGCAAACCCGGCGGTGGAAACAGTGGCACTA AAAAACGATGATGTCTCCCCGAAACTTTGTATCTGGACTCACCTTTTCACAGTAGTATAAGGGTTGCAGCTGAATGGCTCTAAAAGAGTT TTATTTGTCCAGTGAAAATGAATAGGTTCAGGGATGAGCAACAGCCCATAAAAAATGGGAACTGGAAGTTTTATAATAGGAGTTAGAACA GGGCTGTTTTCCCAGCTACTTGCTAACTGACGAAGTGGATTCTTGTGGCAAAATAAATATTGTGGTTTTATAGTGTGAAGTTTTCCCAAT TTTTCATTGTGAGCTGTTTAAAAAAGACTATATCTAGATTGTTAACTCTCGTCCATCCTTCTGTTCTGGGGGCCTTCAGAGTCCCTGTGA CAGCACCCCCAAACCTTCCAGTTCTCTGGGTGTTACTAATACTCAAGCATGCACATACCAGCTTGCTAGGACAGAAACTGTAAAAAGAAA GTAAGTTTCTTCGTTACAAAAAACTTCCTGATTTTCCTTTTCATGCTTTACGGAGGGGATTGTGTCGTGTGAGATTTCCCACAGTACCAG TTTCAAATTTTTTTTTTATTCTTATGCTAAATCATAGGAGAAAAATCTAGATAGCCTTTCTTTAACTGTCTATTTCTACCTGCAAAATGA AGAAAACCTTTCATCTGTTGAAATTTCAATCGATAACCCAGCTGAAGATCTTATGCACAGGACACACTTGGCATATGCTTTACGCAGTTG CTCCGGACAGCTTGCTCGCGCCACTGAGCTTTTCCTGAGGTTTGTGTTCGCCTCTCAAGGAGAGCTTTGATCCTCAGTGGTACGGATGAC TTGATGGGCTCCATGCGGAGCCTGGCCTGCATCCCCCACCACACAGCTCACTCACCCACCAGCTCTAGACTGCAGACGCACAAGGCCTCT GCTCAGAAGCCAGAACACAGCACCTGTGACTCTGTTACTTGAATTTTGTGCTTTTTGATTGGAGTCCTTTGTTGAGTACTTTGTTAATTG AACACTGCCTTTCTCTGGAGAAGGCCCCAGTGCTTTCTAGCTCCCTCTCACTCCTGCCCTTTCTAGCTCTCTCTCACCCAGCGGGTCAGG GATAGCACCTCTTGTCTCCACTATGCAGATGGGAACTCTGAGCCACACAGAGGTGAAGTAGCACTTCAGTTACTCAAGGTCAGTACTCTC GGTATTCCAAGTGACTTAGCCACATTTCCTTCAGTGCAATAGGTGGGTTTAATGCTCTTTGTACACAGATGTATTGGCTACATAGCGTGT AAAAACCAAGACTGGGAAGCCATTCACTAAAATCCCTCCTGACTCAAAGGACCTGTCTCCAGATGGTACAGAGTCCCTTGATGGCATTTT ACAAAACCAGCTCTGACTTCCTTATCCTGAACAGGGAGTTTATTTTAAAAATGCTTCATGCACCTGTTATTTGGCTGAACAGAAGGCTCA CTCCTCAATCCCCTTCTCCTCGCCATCATTAGAGGAATAGACTCAGCCTTCATGTTTGTCTCTGGAAGACGATTGGCGATACTTGCAGGA ATATTGTTGATGCAGCCAATATTAATTTGAGCTAATGGATTGTTAATTCTGAAACGAAAACTGTAACTGTAGAGCAGGCTTTTACTATGA GAGGTACTACTTTTTATAATAGAGAATGTGGTTGTGTGGGCTTTTTTTGAACAGAAAACACAACAATGACCTATACCGTGAGAAAAGCCA TTTTATCTTCTTCGTGGTATTTTTACCCCCAAAGGAACTGAAGATGGAAAATATGACTAATAAGTTATTGCAGTTTTGGTCTTGAATTCT GTGCCATCTGAAGTTAGCATCCAGCTTCTTAAAAAGCAGCCACGCCTACAGCCTGTTTTTTGGGAAGGCTGTAGGTGGAGAGATGGGCTT ATTTTGCATACCACCCTCAGGGCCCAGAGACCCACTGCATTTTCCAAAGTTAAGCAAATGACACCATTTTCTTCCATCAGCTAAACTTTA CAGATAATAGTGTTTCCACCTCATATCCTTTTCTTTGCCCCTTCTCAAATGAGTCAGAATAGTCATGTTCCCCTTGAGGGATGTCTGACT TGAATGGAGAATTGTTCTTTCCTCTCTTGAATCAGCTCACTAGCTCCCTGATGGTCTGGGTTCAAGGAAATGGTTAATGAGGTAGAGGCC ACTTATACAAGTCCTTGGGATTGTACCATTGCTGTCCACAAACTTAGTATCAACAACACATGCTGTGCCCTGTGAACACTCTCCTCTCAC CTATTTCCAGGGTTGGTCTTCCTGAGAAGGGGATGGATGAGGTAACACACAGTTTGGGATACGTATCTGTTGAATGAATGAATAAGTGAA AGGATAATAGTCCTCTGAGGTAAAAATGGCCTTGTCAGAATTTTGAAAATCCAACAGATTCCTATTAAAGCACTCTGTGTACCAATAACA TGCATGCATTGTACCAAGTAATCACAATGTGAATTGGTCAATTTATGAGCCTTGCCTACTTTAGAAAATAAAGAAACCTGCAGTAGCCTC TACCACACAGCATGTACAAAGACCAGTATGGACTTGCTATCTTCCCTATGTATTGGACACTGTATGCAAACACCAGAAGTACTTAACAAG TAGTGGTTTCTTGATTTTTAGATATGTCTGTAGCCTCTTAGCCCTTTTGCCGGGAATCAACTCATTCTGATGCCTCTGCACCTCAGTTCC TCTTACAAAAGCCTCCAGATGATCTAAATCTAGTTAGCAATGTCAGCCTGTGGACTGCAGCTGTTTGGGACATTGTATTCCTTTGTTTGT CTCTTGTTGTTCTGAAGGATTGTATTGATCACAAAGCTATATGCATAAAGATTCTCATTGTTGTAACTGTTCTGCCATTTTCTGAGTGCA AGCATGGAACACTGTTGTGACAGTCCCTTCTCCCTTCTTCCTTCTTCCTTCACCCCCAACCCCAGACCCCCCTTGGTCACATGAACCAGG GAAACAGCCCAATAAGCTCTATCTCCCCCAGTCTAATCGCTGGGTTGCAGGGTGGCCTGTGACCTGCCCAGCATTTGCAGACTCGCTGGT TCCTGAATATGAGTAAGCACAGAGTTTACCTAGAGAGTTTACCTAAAATTAACCTTTAGATCTACTATTTATTTTTGTCTTAATAAAATG AACAATAAATATAGTTTAGCTGCATGGCATTAAGGATTCTGTATGAATAGATGTATAGTTGCTGCCATCTCCCCATATAAAAACTCTCTT TACATCGTTTCTGAGCCACTTTCTTTGCTGTCTGCAGCATTTAAAATATATTATTTTTCCTAATTAGAAAAGTCACAGGTTTTAGAAAAT TGGGAAAACAAAAAGAGCATAAAGAATCATCAATACTCTGATATAGATATAGATCTTTCCAGTACGTTTGTGTATGTGTGTACACGCCAT TATCTACAAAAAAGTTATGTTGAACATGGTAGTTTAAGCTGTCTTTCTGGTAAATGCTCTTATACAATATGATTTTTAGTGACTAATATT CCCTAATGTGTTCATGCCAGAATTCACATAACCAGTACCTTGTCAAATAGGAGGTTTCTGATTAGATAGTAGTAGAGACAGTATCCTGTT ACATGTATGTACATAGCCCGAATTATTTTCTTAGGATATGCGTATAGAAGTGGAGTTGAAGGGTCAGGAAATATGTCCATTTTTAAGATA CATATATCTCCAAATTGCCATTCTTAAAGGTTGGAGTTATACAAGTAGTGAATGAGAATGCCTGCTTCTCTACATCCTGGAAGAGGCAGC AGTCTCTTTCCTTTTTTTTCCTTTCTATGACTTCTAGTGTGGAAGTGCCAACAGAAGTGTTTTAGAAGCAGTGATAATGAACACTCATAA CACCCATACCTCATTCCTGACTTTTAAAAGAAGCATTAAGTAAGATGTTGAGGTTTCTGGTAGGTGCCTATTATTAGGTTAAGAAAATTC CCTTTTATTCTTTGCTTGCTAAGAGTTTTCTTCATCAACAGGTATTGAATTTCATAAAAAGAACTTTAATTGTATCTTTTGAGAAGGGAA TAGTACTTGAGACTTGGTATCCTGAACTCAAAGAAATAGCCATTACTAGGTTTTGTCAAAGAATACCAGATATTTTAGAGTTGGAAGTTA TGCAGTAAAAGCTTTATGTGCAAATGTTCATTGAAGTATTAAATGTACTAATGGAAACCTGAAAACAATATAAACATCTGGGAATAGGGG AGATGTTTGGATGAATTATGATTCATCCCCAGGATGGAAATGTGAAGGCCGGTGAGTATTTGGACCATTGAAGTGGGAGTTATCTGTTAT CCACATCAGGCAGCTCAGAGTAAAGTCAGCAAGTCTACAGTCATAGAGCCACCAGGATACAGTGATGGATGGGAGGCCTTTGCTGGACAG TGGCTGAAGGCAGAACTGTTGGAGTGGTTCTTCCACAAAGGCAGCCAGTGCTCACCTGAATGGGGACTGGTACTGTAGGTATTGGGTCAG CTTTCATGCCGTTCCCTGCTGGCCATCTCCCAATGCTGAATGTCTGACTCAGTTCAGGCTGCTGTAACAAAGTACCATAGACTGAGGTGG CTTAAACACAGACATTTCTTTCTCACAGTTCTGGAGGCTGAGAAGTCAAAGATCAACGTGTCTGCAAATTTGGTATCTGGTGAGGAAGGG CCCTCTTCCTGGTTTGCAGATGGCTACCTTCTCACTGTGTCCTCACACAATGGAGAAAGGGAGTATGTTTTGGTCTCTTCCTCTTCTGAT AAGGGCACTAACCTCATCATGAGGGTCCCATCCTCCTGGTGTCATCTAAACCTAATTACCTCCCAATGGCCCCGCCTTCAAATACCATCA CGTTGAAGGTTGCTTCCTTCCTGGTCGTTTGCTCTGGTGAGACCAAATGACCTGCAAAGTGTCACTTGATTCCATTCTCTCCATCCCTTC CATCCCAGGCAATCTTTATCTAGCTACACCAACCTGTGCCCCAGGGGCTTCAAGAGTTGTTGTTGTTTTAACATTAAAAAACCAGAAAGT TCACTTGTTTCTTAGTGTTTACATCCTTGCTATAACAATTCTAGTTTTCCTTTAGGCAATGCTGATCACTGGGAAGGAGGTGGATCAATT CTCCTATGGGACCAACAGTTTTCTGGGAAGAAACTTCCTGATACCTCAGCCTAGGAATCTCCCTATCCCTGGAGAGTCCAGGAATCTATA >86350_86350_2_SRGAP1-TBC1D30_SRGAP1_chr12_64410792_ENST00000355086_TBC1D30_chr12_65258448_ENST00000542120_length(amino acids)=578AA_BP=163 MSTPSRFKKDKEIIAEYESQVKEIRAQLVEQQKCLEQQTEMRVQLLQDLQDFFRKKAEIETEYSRNLEKLAERFMAKTRSTKDHQQYKKD QNLLSPVNCWYLLLNQVRRESKDHATLSDIYLNNVIMRFMQISEDSTRMFKKSKEIAFQLHEDLMKVLNELYTTVYSMAPFPFPQLAELR EKYTYNITPFPATVKPTSVSGRHSKARDSDEENDPDDEDAVVNAVGCLGPFSGFLAPELQKYQKQIKEPNEEQSLRSNNIAELSPGAINS CRSEYHAAFNSMMMERMTTDINALKRQYSRIKKKQQQQVHQVYIRADKGPVTSILPSQVNSSPVINHLLLGKKMKMTNRAAKNAVIHIPG HTGGKISPVPYEDLKTKLNSPWRTHIRVHKKNMPRTKSHPGCGDTVGLIDEQNEASKTNGLGAAEAFPSGCTATAGREGSSPEGSTRRTI EGQSPEPVFGDADVDVSAVQAKLGALELNQRDAAAETELRVHPPCQRHCPEPPSAPEENKATSKAPQGSNSKTPIFSPFPSVKPLRKSAT -------------------------------------------------------------- >86350_86350_3_SRGAP1-TBC1D30_SRGAP1_chr12_64410792_ENST00000357825_TBC1D30_chr12_65258448_ENST00000229088_length(transcript)=4308nt_BP=545nt GTTGTGACCACTGAACAAAACTTGCCCATTGAAAGCAAACCCGGAACAGCTGGATAATGTCCACCCCGAGCCGATTCAAGAAGGACAAAG AGATCATAGCCGAGTATGAAAGTCAAGTCAAAGAAATTCGAGCTCAACTGGTAGAACAACAAAAATGCCTGGAGCAGCAAACGGAGATGC GAGTTCAGCTTCTCCAGGATCTGCAAGATTTCTTCCGAAAAAAAGCTGAAATTGAGACGGAATATTCCCGGAATCTAGAGAAGTTAGCAG AAAGGTTCATGGCAAAAACAAGAAGCACTAAGGATCATCAACAATACAAGAAAGACCAGAACCTGTTGTCTCCAGTGAACTGCTGGTATT TGCTCCTGAACCAAGTAAGGAGAGAAAGCAAAGACCATGCAACCTTGAGTGACATCTATCTGAACAATGTGATTATGCGGTTCATGCAGA TAAGTGAGGATTCTACCAGGATGTTTAAAAAGAGCAAAGAGATTGCATTCCAACTTCATGAGGATTTAATGAAGGTTCTTAATGAGCTTT ATACGACTGTTTATTCCATGGCTCCGTTCCCTTTCCCACAATTGGCAGAGTTGAGGGAAAAATACACCTACAACATTACACCGTTCCCAG CCACAGTTAAACCCACCTCAGTTTCTGGACGACATAGTAAGGCCAGAGACAGTGATGAAGAGAATGACCCAGACGATGAGGATGCTGTCG TTAATGCAGTGGGGTGTCTTGGACCTTTTAGTGGGTTCCTGGCTCCTGAACTGCAGAAGTACCAAAAACAAATTAAAGAGCCAAATGAGG AGCAGAGTCTGAGATCTAATAACATTGCAGAGCTGAGTCCAGGAGCAATCAATTCCTGTCGAAGTGAATACCATGCAGCTTTTAACAGTA TGATGATGGAACGCATGACCACAGATATCAATGCACTGAAGCGGCAGTACTCTCGAATTAAAAAGAAGCAACAGCAGCAGGTTCATCAGG TGTACATCAGGGCAGACAAAGGGCCAGTGACCAGCATTCTCCCGTCTCAGGTAAACAGTTCTCCAGTTATAAACCACCTTCTTTTAGGAA AGAAGATGAAAATGACTAACAGAGCTGCCAAGAATGCTGTCATCCACATCCCTGGTCACACAGGAGGGAAAATATCTCCTGTCCCCTACG AAGACCTTAAGACGAAGCTCAACTCCCCGTGGCGAACTCACATCCGAGTCCACAAAAAGAACATGCCAAGGACCAAGAGTCATCCGGGCT GTGGGGACACCGTAGGGCTGATAGATGAGCAGAACGAGGCCAGCAAGACCAATGGGCTGGGGGCAGCAGAGGCATTCCCCTCTGGTTGTA CAGCGACAGCTGGGAGAGAAGGCAGCAGCCCTGAAGGCAGTACCAGGAGGACGATCGAGGGGCAGTCTCCGGAGCCGGTGTTCGGAGATG CTGATGTGGATGTGTCTGCAGTTCAGGCGAAGTTGGGAGCCCTGGAACTGAACCAGAGGGATGCTGCAGCTGAAACTGAGCTCAGGGTGC ACCCACCCTGCCAGCGGCACTGCCCAGAGCCGCCGAGTGCACCCGAAGAAAACAAAGCCACCAGCAAAGCTCCCCAAGGCAGCAACTCAA AAACCCCCATCTTTAGCCCTTTTCCCAGCGTCAAGCCCCTGCGGAAATCTGCTACTGCCAGGAACTTGGGATTATATGGCCCTACAGAAA GAACCCCAACTGTGCACTTTCCTCAAATGAGTAGGAGCTTCAGCAAACCCGGCGGTGGAAACAGTGGCACTAAAAAACGATGATGTCTCC CCGAAACTTTGTATCTGGACTCACCTTTTCACAGTAGTATAAGGGTTGCAGCTGAATGGCTCTAAAAGAGTTTTATTTGTCCAGTGAAAA TGAATAGGTTCAGGGATGAGCAACAGCCCATAAAAAATGGGAACTGGAAGTTTTATAATAGGAGTTAGAACAGGGCTGTTTTCCCAGCTA CTTGCTAACTGACGAAGTGGATTCTTGTGGCAAAATAAATATTGTGGTTTTATAGTGTGAAGTTTTCCCAATTTTTCATTGTGAGCTGTT TAAAAAAGACTATATCTAGATTGTTAACTCTCGTCCATCCTTCTGTTCTGGGGGCCTTCAGAGTCCCTGTGACAGCACCCCCAAACCTTC CAGTTCTCTGGGTGTTACTAATACTCAAGCATGCACATACCAGCTTGCTAGGACAGAAACTGTAAAAAGAAAGTAAGTTTCTTCGTTACA AAAAACTTCCTGATTTTCCTTTTCATGCTTTACGGAGGGGATTGTGTCGTGTGAGATTTCCCACAGTACCAGTTTCAAATTTTTTTTTTA TTCTTATGCTAAATCATAGGAGAAAAATCTAGATAGCCTTTCTTTAACTGTCTATTTCTACCTGCAAAATGAAGAAAACCTTTCATCTGT TGAAATTTCAATCGATAACCCAGCTGAAGATCTTATGCACAGGACACACTTGGCATATGCTTTACGCAGTTGCTCCGGACAGCTTGCTCG CGCCACTGAGCTTTTCCTGAGGTTTGTGTTCGCCTCTCAAGGAGAGCTTTGATCCTCAGTGGTACGGATGACTTGATGGGCTCCATGCGG AGCCTGGCCTGCATCCCCCACCACACAGCTCACTCACCCACCAGCTCTAGACTGCAGACGCACAAGGCCTCTGCTCAGAAGCCAGAACAC AGCACCTGTGACTCTGTTACTTGAATTTTGTGCTTTTTGATTGGAGTCCTTTGTTGAGTACTTTGTTAATTGAACACTGCCTTTCTCTGG AGAAGGCCCCAGTGCTTTCTAGCTCCCTCTCACTCCTGCCCTTTCTAGCTCTCTCTCACCCAGCGGGTCAGGGATAGCACCTCTTGTCTC CACTATGCAGATGGGAACTCTGAGCCACACAGAGGTGAAGTAGCACTTCAGTTACTCAAGGTCAGTACTCTCGGTATTCCAAGTGACTTA GCCACATTTCCTTCAGTGCAATAGGTGGGTTTAATGCTCTTTGTACACAGATGTATTGGCTACATAGCGTGTAAAAACCAAGACTGGGAA GCCATTCACTAAAATCCCTCCTGACTCAAAGGACCTGTCTCCAGATGGTACAGAGTCCCTTGATGGCATTTTACAAAACCAGCTCTGACT TCCTTATCCTGAACAGGGAGTTTATTTTAAAAATGCTTCATGCACCTGTTATTTGGCTGAACAGAAGGCTCACTCCTCAATCCCCTTCTC CTCGCCATCATTAGAGGAATAGACTCAGCCTTCATGTTTGTCTCTGGAAGACGATTGGCGATACTTGCAGGAATATTGTTGATGCAGCCA ATATTAATTTGAGCTAATGGATTGTTAATTCTGAAACGAAAACTGTAACTGTAGAGCAGGCTTTTACTATGAGAGGTACTACTTTTTATA ATAGAGAATGTGGTTGTGTGGGCTTTTTTTGAACAGAAAACACAACAATGACCTATACCGTGAGAAAAGCCATTTTATCTTCTTCGTGGT ATTTTTACCCCCAAAGGAACTGAAGATGGAAAATATGACTAATAAGTTATTGCAGTTTTGGTCTTGAATTCTGTGCCATCTGAAGTTAGC ATCCAGCTTCTTAAAAAGCAGCCACGCCTACAGCCTGTTTTTTGGGAAGGCTGTAGGTGGAGAGATGGGCTTATTTTGCATACCACCCTC AGGGCCCAGAGACCCACTGCATTTTCCAAAGTTAAGCAAATGACACCATTTTCTTCCATCAGCTAAACTTTACAGATAATAGTGTTTCCA CCTCATATCCTTTTCTTTGCCCCTTCTCAAATGAGTCAGAATAGTCATGTTCCCCTTGAGGGATGTCTGACTTGAATGGAGAATTGTTCT TTCCTCTCTTGAATCAGCTCACTAGCTCCCTGATGGTCTGGGTTCAAGGAAATGGTTAATGAGGTAGAGGCCACTTATACAAGTCCTTGG GATTGTACCATTGCTGTCCACAAACTTAGTATCAACAACACATGCTGTGCCCTGTGAACACTCTCCTCTCACCTATTTCCAGGGTTGGTC TTCCTGAGAAGGGGATGGATGAGGTAACACACAGTTTGGGATACGTATCTGTTGAATGAATGAATAAGTGAAAGGATAATAGTCCTCTGA GGTAAAAATGGCCTTGTCAGAATTTTGAAAATCCAACAGATTCCTATTAAAGCACTCTGTGTACCAATAACATGCATGCATTGTACCAAG >86350_86350_3_SRGAP1-TBC1D30_SRGAP1_chr12_64410792_ENST00000357825_TBC1D30_chr12_65258448_ENST00000229088_length(amino acids)=578AA_BP=163 MSTPSRFKKDKEIIAEYESQVKEIRAQLVEQQKCLEQQTEMRVQLLQDLQDFFRKKAEIETEYSRNLEKLAERFMAKTRSTKDHQQYKKD QNLLSPVNCWYLLLNQVRRESKDHATLSDIYLNNVIMRFMQISEDSTRMFKKSKEIAFQLHEDLMKVLNELYTTVYSMAPFPFPQLAELR EKYTYNITPFPATVKPTSVSGRHSKARDSDEENDPDDEDAVVNAVGCLGPFSGFLAPELQKYQKQIKEPNEEQSLRSNNIAELSPGAINS CRSEYHAAFNSMMMERMTTDINALKRQYSRIKKKQQQQVHQVYIRADKGPVTSILPSQVNSSPVINHLLLGKKMKMTNRAAKNAVIHIPG HTGGKISPVPYEDLKTKLNSPWRTHIRVHKKNMPRTKSHPGCGDTVGLIDEQNEASKTNGLGAAEAFPSGCTATAGREGSSPEGSTRRTI EGQSPEPVFGDADVDVSAVQAKLGALELNQRDAAAETELRVHPPCQRHCPEPPSAPEENKATSKAPQGSNSKTPIFSPFPSVKPLRKSAT -------------------------------------------------------------- >86350_86350_4_SRGAP1-TBC1D30_SRGAP1_chr12_64410792_ENST00000357825_TBC1D30_chr12_65258448_ENST00000542120_length(transcript)=7037nt_BP=545nt GTTGTGACCACTGAACAAAACTTGCCCATTGAAAGCAAACCCGGAACAGCTGGATAATGTCCACCCCGAGCCGATTCAAGAAGGACAAAG AGATCATAGCCGAGTATGAAAGTCAAGTCAAAGAAATTCGAGCTCAACTGGTAGAACAACAAAAATGCCTGGAGCAGCAAACGGAGATGC GAGTTCAGCTTCTCCAGGATCTGCAAGATTTCTTCCGAAAAAAAGCTGAAATTGAGACGGAATATTCCCGGAATCTAGAGAAGTTAGCAG AAAGGTTCATGGCAAAAACAAGAAGCACTAAGGATCATCAACAATACAAGAAAGACCAGAACCTGTTGTCTCCAGTGAACTGCTGGTATT TGCTCCTGAACCAAGTAAGGAGAGAAAGCAAAGACCATGCAACCTTGAGTGACATCTATCTGAACAATGTGATTATGCGGTTCATGCAGA TAAGTGAGGATTCTACCAGGATGTTTAAAAAGAGCAAAGAGATTGCATTCCAACTTCATGAGGATTTAATGAAGGTTCTTAATGAGCTTT ATACGACTGTTTATTCCATGGCTCCGTTCCCTTTCCCACAATTGGCAGAGTTGAGGGAAAAATACACCTACAACATTACACCGTTCCCAG CCACAGTTAAACCCACCTCAGTTTCTGGACGACATAGTAAGGCCAGAGACAGTGATGAAGAGAATGACCCAGACGATGAGGATGCTGTCG TTAATGCAGTGGGGTGTCTTGGACCTTTTAGTGGGTTCCTGGCTCCTGAACTGCAGAAGTACCAAAAACAAATTAAAGAGCCAAATGAGG AGCAGAGTCTGAGATCTAATAACATTGCAGAGCTGAGTCCAGGAGCAATCAATTCCTGTCGAAGTGAATACCATGCAGCTTTTAACAGTA TGATGATGGAACGCATGACCACAGATATCAATGCACTGAAGCGGCAGTACTCTCGAATTAAAAAGAAGCAACAGCAGCAGGTTCATCAGG TGTACATCAGGGCAGACAAAGGGCCAGTGACCAGCATTCTCCCGTCTCAGGTAAACAGTTCTCCAGTTATAAACCACCTTCTTTTAGGAA AGAAGATGAAAATGACTAACAGAGCTGCCAAGAATGCTGTCATCCACATCCCTGGTCACACAGGAGGGAAAATATCTCCTGTCCCCTACG AAGACCTTAAGACGAAGCTCAACTCCCCGTGGCGAACTCACATCCGAGTCCACAAAAAGAACATGCCAAGGACCAAGAGTCATCCGGGCT GTGGGGACACCGTAGGGCTGATAGATGAGCAGAACGAGGCCAGCAAGACCAATGGGCTGGGGGCAGCAGAGGCATTCCCCTCTGGTTGTA CAGCGACAGCTGGGAGAGAAGGCAGCAGCCCTGAAGGCAGTACCAGGAGGACGATCGAGGGGCAGTCTCCGGAGCCGGTGTTCGGAGATG CTGATGTGGATGTGTCTGCAGTTCAGGCGAAGTTGGGAGCCCTGGAACTGAACCAGAGGGATGCTGCAGCTGAAACTGAGCTCAGGGTGC ACCCACCCTGCCAGCGGCACTGCCCAGAGCCGCCGAGTGCACCCGAAGAAAACAAAGCCACCAGCAAAGCTCCCCAAGGCAGCAACTCAA AAACCCCCATCTTTAGCCCTTTTCCCAGCGTCAAGCCCCTGCGGAAATCTGCTACTGCCAGGAACTTGGGATTATATGGCCCTACAGAAA GAACCCCAACTGTGCACTTTCCTCAAATGAGTAGGAGCTTCAGCAAACCCGGCGGTGGAAACAGTGGCACTAAAAAACGATGATGTCTCC CCGAAACTTTGTATCTGGACTCACCTTTTCACAGTAGTATAAGGGTTGCAGCTGAATGGCTCTAAAAGAGTTTTATTTGTCCAGTGAAAA TGAATAGGTTCAGGGATGAGCAACAGCCCATAAAAAATGGGAACTGGAAGTTTTATAATAGGAGTTAGAACAGGGCTGTTTTCCCAGCTA CTTGCTAACTGACGAAGTGGATTCTTGTGGCAAAATAAATATTGTGGTTTTATAGTGTGAAGTTTTCCCAATTTTTCATTGTGAGCTGTT TAAAAAAGACTATATCTAGATTGTTAACTCTCGTCCATCCTTCTGTTCTGGGGGCCTTCAGAGTCCCTGTGACAGCACCCCCAAACCTTC CAGTTCTCTGGGTGTTACTAATACTCAAGCATGCACATACCAGCTTGCTAGGACAGAAACTGTAAAAAGAAAGTAAGTTTCTTCGTTACA AAAAACTTCCTGATTTTCCTTTTCATGCTTTACGGAGGGGATTGTGTCGTGTGAGATTTCCCACAGTACCAGTTTCAAATTTTTTTTTTA TTCTTATGCTAAATCATAGGAGAAAAATCTAGATAGCCTTTCTTTAACTGTCTATTTCTACCTGCAAAATGAAGAAAACCTTTCATCTGT TGAAATTTCAATCGATAACCCAGCTGAAGATCTTATGCACAGGACACACTTGGCATATGCTTTACGCAGTTGCTCCGGACAGCTTGCTCG CGCCACTGAGCTTTTCCTGAGGTTTGTGTTCGCCTCTCAAGGAGAGCTTTGATCCTCAGTGGTACGGATGACTTGATGGGCTCCATGCGG AGCCTGGCCTGCATCCCCCACCACACAGCTCACTCACCCACCAGCTCTAGACTGCAGACGCACAAGGCCTCTGCTCAGAAGCCAGAACAC AGCACCTGTGACTCTGTTACTTGAATTTTGTGCTTTTTGATTGGAGTCCTTTGTTGAGTACTTTGTTAATTGAACACTGCCTTTCTCTGG AGAAGGCCCCAGTGCTTTCTAGCTCCCTCTCACTCCTGCCCTTTCTAGCTCTCTCTCACCCAGCGGGTCAGGGATAGCACCTCTTGTCTC CACTATGCAGATGGGAACTCTGAGCCACACAGAGGTGAAGTAGCACTTCAGTTACTCAAGGTCAGTACTCTCGGTATTCCAAGTGACTTA GCCACATTTCCTTCAGTGCAATAGGTGGGTTTAATGCTCTTTGTACACAGATGTATTGGCTACATAGCGTGTAAAAACCAAGACTGGGAA GCCATTCACTAAAATCCCTCCTGACTCAAAGGACCTGTCTCCAGATGGTACAGAGTCCCTTGATGGCATTTTACAAAACCAGCTCTGACT TCCTTATCCTGAACAGGGAGTTTATTTTAAAAATGCTTCATGCACCTGTTATTTGGCTGAACAGAAGGCTCACTCCTCAATCCCCTTCTC CTCGCCATCATTAGAGGAATAGACTCAGCCTTCATGTTTGTCTCTGGAAGACGATTGGCGATACTTGCAGGAATATTGTTGATGCAGCCA ATATTAATTTGAGCTAATGGATTGTTAATTCTGAAACGAAAACTGTAACTGTAGAGCAGGCTTTTACTATGAGAGGTACTACTTTTTATA ATAGAGAATGTGGTTGTGTGGGCTTTTTTTGAACAGAAAACACAACAATGACCTATACCGTGAGAAAAGCCATTTTATCTTCTTCGTGGT ATTTTTACCCCCAAAGGAACTGAAGATGGAAAATATGACTAATAAGTTATTGCAGTTTTGGTCTTGAATTCTGTGCCATCTGAAGTTAGC ATCCAGCTTCTTAAAAAGCAGCCACGCCTACAGCCTGTTTTTTGGGAAGGCTGTAGGTGGAGAGATGGGCTTATTTTGCATACCACCCTC AGGGCCCAGAGACCCACTGCATTTTCCAAAGTTAAGCAAATGACACCATTTTCTTCCATCAGCTAAACTTTACAGATAATAGTGTTTCCA CCTCATATCCTTTTCTTTGCCCCTTCTCAAATGAGTCAGAATAGTCATGTTCCCCTTGAGGGATGTCTGACTTGAATGGAGAATTGTTCT TTCCTCTCTTGAATCAGCTCACTAGCTCCCTGATGGTCTGGGTTCAAGGAAATGGTTAATGAGGTAGAGGCCACTTATACAAGTCCTTGG GATTGTACCATTGCTGTCCACAAACTTAGTATCAACAACACATGCTGTGCCCTGTGAACACTCTCCTCTCACCTATTTCCAGGGTTGGTC TTCCTGAGAAGGGGATGGATGAGGTAACACACAGTTTGGGATACGTATCTGTTGAATGAATGAATAAGTGAAAGGATAATAGTCCTCTGA GGTAAAAATGGCCTTGTCAGAATTTTGAAAATCCAACAGATTCCTATTAAAGCACTCTGTGTACCAATAACATGCATGCATTGTACCAAG TAATCACAATGTGAATTGGTCAATTTATGAGCCTTGCCTACTTTAGAAAATAAAGAAACCTGCAGTAGCCTCTACCACACAGCATGTACA AAGACCAGTATGGACTTGCTATCTTCCCTATGTATTGGACACTGTATGCAAACACCAGAAGTACTTAACAAGTAGTGGTTTCTTGATTTT TAGATATGTCTGTAGCCTCTTAGCCCTTTTGCCGGGAATCAACTCATTCTGATGCCTCTGCACCTCAGTTCCTCTTACAAAAGCCTCCAG ATGATCTAAATCTAGTTAGCAATGTCAGCCTGTGGACTGCAGCTGTTTGGGACATTGTATTCCTTTGTTTGTCTCTTGTTGTTCTGAAGG ATTGTATTGATCACAAAGCTATATGCATAAAGATTCTCATTGTTGTAACTGTTCTGCCATTTTCTGAGTGCAAGCATGGAACACTGTTGT GACAGTCCCTTCTCCCTTCTTCCTTCTTCCTTCACCCCCAACCCCAGACCCCCCTTGGTCACATGAACCAGGGAAACAGCCCAATAAGCT CTATCTCCCCCAGTCTAATCGCTGGGTTGCAGGGTGGCCTGTGACCTGCCCAGCATTTGCAGACTCGCTGGTTCCTGAATATGAGTAAGC ACAGAGTTTACCTAGAGAGTTTACCTAAAATTAACCTTTAGATCTACTATTTATTTTTGTCTTAATAAAATGAACAATAAATATAGTTTA GCTGCATGGCATTAAGGATTCTGTATGAATAGATGTATAGTTGCTGCCATCTCCCCATATAAAAACTCTCTTTACATCGTTTCTGAGCCA CTTTCTTTGCTGTCTGCAGCATTTAAAATATATTATTTTTCCTAATTAGAAAAGTCACAGGTTTTAGAAAATTGGGAAAACAAAAAGAGC ATAAAGAATCATCAATACTCTGATATAGATATAGATCTTTCCAGTACGTTTGTGTATGTGTGTACACGCCATTATCTACAAAAAAGTTAT GTTGAACATGGTAGTTTAAGCTGTCTTTCTGGTAAATGCTCTTATACAATATGATTTTTAGTGACTAATATTCCCTAATGTGTTCATGCC AGAATTCACATAACCAGTACCTTGTCAAATAGGAGGTTTCTGATTAGATAGTAGTAGAGACAGTATCCTGTTACATGTATGTACATAGCC CGAATTATTTTCTTAGGATATGCGTATAGAAGTGGAGTTGAAGGGTCAGGAAATATGTCCATTTTTAAGATACATATATCTCCAAATTGC CATTCTTAAAGGTTGGAGTTATACAAGTAGTGAATGAGAATGCCTGCTTCTCTACATCCTGGAAGAGGCAGCAGTCTCTTTCCTTTTTTT TCCTTTCTATGACTTCTAGTGTGGAAGTGCCAACAGAAGTGTTTTAGAAGCAGTGATAATGAACACTCATAACACCCATACCTCATTCCT GACTTTTAAAAGAAGCATTAAGTAAGATGTTGAGGTTTCTGGTAGGTGCCTATTATTAGGTTAAGAAAATTCCCTTTTATTCTTTGCTTG CTAAGAGTTTTCTTCATCAACAGGTATTGAATTTCATAAAAAGAACTTTAATTGTATCTTTTGAGAAGGGAATAGTACTTGAGACTTGGT ATCCTGAACTCAAAGAAATAGCCATTACTAGGTTTTGTCAAAGAATACCAGATATTTTAGAGTTGGAAGTTATGCAGTAAAAGCTTTATG TGCAAATGTTCATTGAAGTATTAAATGTACTAATGGAAACCTGAAAACAATATAAACATCTGGGAATAGGGGAGATGTTTGGATGAATTA TGATTCATCCCCAGGATGGAAATGTGAAGGCCGGTGAGTATTTGGACCATTGAAGTGGGAGTTATCTGTTATCCACATCAGGCAGCTCAG AGTAAAGTCAGCAAGTCTACAGTCATAGAGCCACCAGGATACAGTGATGGATGGGAGGCCTTTGCTGGACAGTGGCTGAAGGCAGAACTG TTGGAGTGGTTCTTCCACAAAGGCAGCCAGTGCTCACCTGAATGGGGACTGGTACTGTAGGTATTGGGTCAGCTTTCATGCCGTTCCCTG CTGGCCATCTCCCAATGCTGAATGTCTGACTCAGTTCAGGCTGCTGTAACAAAGTACCATAGACTGAGGTGGCTTAAACACAGACATTTC TTTCTCACAGTTCTGGAGGCTGAGAAGTCAAAGATCAACGTGTCTGCAAATTTGGTATCTGGTGAGGAAGGGCCCTCTTCCTGGTTTGCA GATGGCTACCTTCTCACTGTGTCCTCACACAATGGAGAAAGGGAGTATGTTTTGGTCTCTTCCTCTTCTGATAAGGGCACTAACCTCATC ATGAGGGTCCCATCCTCCTGGTGTCATCTAAACCTAATTACCTCCCAATGGCCCCGCCTTCAAATACCATCACGTTGAAGGTTGCTTCCT TCCTGGTCGTTTGCTCTGGTGAGACCAAATGACCTGCAAAGTGTCACTTGATTCCATTCTCTCCATCCCTTCCATCCCAGGCAATCTTTA TCTAGCTACACCAACCTGTGCCCCAGGGGCTTCAAGAGTTGTTGTTGTTTTAACATTAAAAAACCAGAAAGTTCACTTGTTTCTTAGTGT TTACATCCTTGCTATAACAATTCTAGTTTTCCTTTAGGCAATGCTGATCACTGGGAAGGAGGTGGATCAATTCTCCTATGGGACCAACAG TTTTCTGGGAAGAAACTTCCTGATACCTCAGCCTAGGAATCTCCCTATCCCTGGAGAGTCCAGGAATCTATATTAAAACATGAAACAAAG >86350_86350_4_SRGAP1-TBC1D30_SRGAP1_chr12_64410792_ENST00000357825_TBC1D30_chr12_65258448_ENST00000542120_length(amino acids)=578AA_BP=163 MSTPSRFKKDKEIIAEYESQVKEIRAQLVEQQKCLEQQTEMRVQLLQDLQDFFRKKAEIETEYSRNLEKLAERFMAKTRSTKDHQQYKKD QNLLSPVNCWYLLLNQVRRESKDHATLSDIYLNNVIMRFMQISEDSTRMFKKSKEIAFQLHEDLMKVLNELYTTVYSMAPFPFPQLAELR EKYTYNITPFPATVKPTSVSGRHSKARDSDEENDPDDEDAVVNAVGCLGPFSGFLAPELQKYQKQIKEPNEEQSLRSNNIAELSPGAINS CRSEYHAAFNSMMMERMTTDINALKRQYSRIKKKQQQQVHQVYIRADKGPVTSILPSQVNSSPVINHLLLGKKMKMTNRAAKNAVIHIPG HTGGKISPVPYEDLKTKLNSPWRTHIRVHKKNMPRTKSHPGCGDTVGLIDEQNEASKTNGLGAAEAFPSGCTATAGREGSSPEGSTRRTI EGQSPEPVFGDADVDVSAVQAKLGALELNQRDAAAETELRVHPPCQRHCPEPPSAPEENKATSKAPQGSNSKTPIFSPFPSVKPLRKSAT -------------------------------------------------------------- >86350_86350_5_SRGAP1-TBC1D30_SRGAP1_chr12_64410792_ENST00000543397_TBC1D30_chr12_65258448_ENST00000229088_length(transcript)=5607nt_BP=1844nt CTTGCTGTTAATGAACTTGGTTAAACATGGTCAAGTGTATGTATGTATATATTATCAGTACTGGCCTTCTCTATCTAAGAGGAATAGCAA GAAATTTAGAGACATTATTTGGACATTGATTTCTACTAACTCCACTGAATTAGATTCAGCCTTCACTTTTTGGGAAATGCACGGACACTG GGAAAGATGAAATGAAGAAGTTTTCCAGCATGATGTTCTTGTCTTTGGAGCTTAGCCTTACTTAGGTCTTAGAACAAAAACAAGTCGGTA GTTATTAGTTACTGTATCTCATTTTCCAAAACACACGTTTCTTTGTTACAGTCATTTACACATATTTTTGCATGCCACATTTTTGCTTTT GAGCTTTTGCTGAATCACTAAATGACCACCTTTCATGTTCCTAATGTATTAAAATTATCAGAGGATTCTTTGAGGATTAAATGTGTCAGT AAGGGTATTATTTTGAACAATGCGTAAAAGGTGAAGGCCAGCTGAAGAGGCCTTTTTGTTGTGAACAGAATAATATACTGGAATCTGAGG ACTGCACTGTTATGAATGGATTATTTGGCTATGGAAAGAAGTTATTTTTAGGCACAGCATCCCTATAAGCCCTGAAGCTATGTGTTTTAC AAACTAGAAATTATGCACTAAATAAAAATTACCAGATGTCAGTCTCTGTATGTGCCAAATGGCAAATGTGTAATGGTTCAGAGCCTGGAA GAAATGATGCTTATTTCTTTGCCATTCAAACTCAAAAGGGATAGCTGAGGTAGAGTGCTGTTGAAAAAATTGCAGTGTTTCCAGCTACCC AAAGATGTTACGAATTGTTATCTGAAAGGCTTTCATTCTTTCCCCTCATGGCTCGTTGTGTGTTTGTGGCATTACAAATGTAACCCACAT ATTTATTCTAATTTATTACATTCTTTCCTGAGGCTCCTCTTGTTCTTTTAAAGGGTCAGCAGATAACTTATTTTAAGAATCAACCTGGAC ACAGTATTCTAACAAAGGTCCAATACAGAGCTAAATAAATAATAGGAGTCATAGCCAGACACAGTGACTCACGCCTGTAATCCCAACATT TTGGGAGGCCAAGGCGGGTGGATTACCTGGTGGTGCATGCCTGTAGTCTCAGCTACTCAGGAGGCTGAGGCAGGAGAATCACTTGAACCC GGGACGCAGAGGTTACAGTGAACCGAGATTGCGCCACTGCACTCCAGCCTGGGCAACAGAGCGAGACCTCTATCTCAAAAATAAATAAAT AAATACATTTAAAATATATATATATATATATATATATATATATATATATATATATATATATATATATATATTTATATATATTTCGTGACT TATATCTTGCACATACCAGCATACCTCATTAATTTTAATGTAACCATCCATTGGCTTCTCTTCTCTCCTTAGAAATTCGAGCTCAACTGG TAGAACAACAAAAATGCCTGGAGCAGCAAACGGAGATGCGAGTTCAGCTTCTCCAGGATCTGCAAGATTTCTTCCGAAAAAAAGCTGAAA TTGAGACGGAATATTCCCGGAATCTAGAGAAGTTAGCAGAAAGGTTCATGGCAAAAACAAGAAGCACTAAGGATCATCAACAATACAAGA AAGACCAGAACCTGTTGTCTCCAGTGAACTGCTGGTATTTGCTCCTGAACCAAGTAAGGAGAGAAAGCAAAGACCATGCAACCTTGAGTG ACATCTATCTGAACAATGTGATTATGCGGTTCATGCAGATAAGTGAGGATTCTACCAGGATGTTTAAAAAGAGCAAAGAGATTGCATTCC AACTTCATGAGGATTTAATGAAGGTTCTTAATGAGCTTTATACGACTGTTTATTCCATGGCTCCGTTCCCTTTCCCACAATTGGCAGAGT TGAGGGAAAAATACACCTACAACATTACACCGTTCCCAGCCACAGTTAAACCCACCTCAGTTTCTGGACGACATAGTAAGGCCAGAGACA GTGATGAAGAGAATGACCCAGACGATGAGGATGCTGTCGTTAATGCAGTGGGGTGTCTTGGACCTTTTAGTGGGTTCCTGGCTCCTGAAC TGCAGAAGTACCAAAAACAAATTAAAGAGCCAAATGAGGAGCAGAGTCTGAGATCTAATAACATTGCAGAGCTGAGTCCAGGAGCAATCA ATTCCTGTCGAAGTGAATACCATGCAGCTTTTAACAGTATGATGATGGAACGCATGACCACAGATATCAATGCACTGAAGCGGCAGTACT CTCGAATTAAAAAGAAGCAACAGCAGCAGGTTCATCAGGTGTACATCAGGGCAGACAAAGGGCCAGTGACCAGCATTCTCCCGTCTCAGG TAAACAGTTCTCCAGTTATAAACCACCTTCTTTTAGGAAAGAAGATGAAAATGACTAACAGAGCTGCCAAGAATGCTGTCATCCACATCC CTGGTCACACAGGAGGGAAAATATCTCCTGTCCCCTACGAAGACCTTAAGACGAAGCTCAACTCCCCGTGGCGAACTCACATCCGAGTCC ACAAAAAGAACATGCCAAGGACCAAGAGTCATCCGGGCTGTGGGGACACCGTAGGGCTGATAGATGAGCAGAACGAGGCCAGCAAGACCA ATGGGCTGGGGGCAGCAGAGGCATTCCCCTCTGGTTGTACAGCGACAGCTGGGAGAGAAGGCAGCAGCCCTGAAGGCAGTACCAGGAGGA CGATCGAGGGGCAGTCTCCGGAGCCGGTGTTCGGAGATGCTGATGTGGATGTGTCTGCAGTTCAGGCGAAGTTGGGAGCCCTGGAACTGA ACCAGAGGGATGCTGCAGCTGAAACTGAGCTCAGGGTGCACCCACCCTGCCAGCGGCACTGCCCAGAGCCGCCGAGTGCACCCGAAGAAA ACAAAGCCACCAGCAAAGCTCCCCAAGGCAGCAACTCAAAAACCCCCATCTTTAGCCCTTTTCCCAGCGTCAAGCCCCTGCGGAAATCTG CTACTGCCAGGAACTTGGGATTATATGGCCCTACAGAAAGAACCCCAACTGTGCACTTTCCTCAAATGAGTAGGAGCTTCAGCAAACCCG GCGGTGGAAACAGTGGCACTAAAAAACGATGATGTCTCCCCGAAACTTTGTATCTGGACTCACCTTTTCACAGTAGTATAAGGGTTGCAG CTGAATGGCTCTAAAAGAGTTTTATTTGTCCAGTGAAAATGAATAGGTTCAGGGATGAGCAACAGCCCATAAAAAATGGGAACTGGAAGT TTTATAATAGGAGTTAGAACAGGGCTGTTTTCCCAGCTACTTGCTAACTGACGAAGTGGATTCTTGTGGCAAAATAAATATTGTGGTTTT ATAGTGTGAAGTTTTCCCAATTTTTCATTGTGAGCTGTTTAAAAAAGACTATATCTAGATTGTTAACTCTCGTCCATCCTTCTGTTCTGG GGGCCTTCAGAGTCCCTGTGACAGCACCCCCAAACCTTCCAGTTCTCTGGGTGTTACTAATACTCAAGCATGCACATACCAGCTTGCTAG GACAGAAACTGTAAAAAGAAAGTAAGTTTCTTCGTTACAAAAAACTTCCTGATTTTCCTTTTCATGCTTTACGGAGGGGATTGTGTCGTG TGAGATTTCCCACAGTACCAGTTTCAAATTTTTTTTTTATTCTTATGCTAAATCATAGGAGAAAAATCTAGATAGCCTTTCTTTAACTGT CTATTTCTACCTGCAAAATGAAGAAAACCTTTCATCTGTTGAAATTTCAATCGATAACCCAGCTGAAGATCTTATGCACAGGACACACTT GGCATATGCTTTACGCAGTTGCTCCGGACAGCTTGCTCGCGCCACTGAGCTTTTCCTGAGGTTTGTGTTCGCCTCTCAAGGAGAGCTTTG ATCCTCAGTGGTACGGATGACTTGATGGGCTCCATGCGGAGCCTGGCCTGCATCCCCCACCACACAGCTCACTCACCCACCAGCTCTAGA CTGCAGACGCACAAGGCCTCTGCTCAGAAGCCAGAACACAGCACCTGTGACTCTGTTACTTGAATTTTGTGCTTTTTGATTGGAGTCCTT TGTTGAGTACTTTGTTAATTGAACACTGCCTTTCTCTGGAGAAGGCCCCAGTGCTTTCTAGCTCCCTCTCACTCCTGCCCTTTCTAGCTC TCTCTCACCCAGCGGGTCAGGGATAGCACCTCTTGTCTCCACTATGCAGATGGGAACTCTGAGCCACACAGAGGTGAAGTAGCACTTCAG TTACTCAAGGTCAGTACTCTCGGTATTCCAAGTGACTTAGCCACATTTCCTTCAGTGCAATAGGTGGGTTTAATGCTCTTTGTACACAGA TGTATTGGCTACATAGCGTGTAAAAACCAAGACTGGGAAGCCATTCACTAAAATCCCTCCTGACTCAAAGGACCTGTCTCCAGATGGTAC AGAGTCCCTTGATGGCATTTTACAAAACCAGCTCTGACTTCCTTATCCTGAACAGGGAGTTTATTTTAAAAATGCTTCATGCACCTGTTA TTTGGCTGAACAGAAGGCTCACTCCTCAATCCCCTTCTCCTCGCCATCATTAGAGGAATAGACTCAGCCTTCATGTTTGTCTCTGGAAGA CGATTGGCGATACTTGCAGGAATATTGTTGATGCAGCCAATATTAATTTGAGCTAATGGATTGTTAATTCTGAAACGAAAACTGTAACTG TAGAGCAGGCTTTTACTATGAGAGGTACTACTTTTTATAATAGAGAATGTGGTTGTGTGGGCTTTTTTTGAACAGAAAACACAACAATGA CCTATACCGTGAGAAAAGCCATTTTATCTTCTTCGTGGTATTTTTACCCCCAAAGGAACTGAAGATGGAAAATATGACTAATAAGTTATT GCAGTTTTGGTCTTGAATTCTGTGCCATCTGAAGTTAGCATCCAGCTTCTTAAAAAGCAGCCACGCCTACAGCCTGTTTTTTGGGAAGGC TGTAGGTGGAGAGATGGGCTTATTTTGCATACCACCCTCAGGGCCCAGAGACCCACTGCATTTTCCAAAGTTAAGCAAATGACACCATTT TCTTCCATCAGCTAAACTTTACAGATAATAGTGTTTCCACCTCATATCCTTTTCTTTGCCCCTTCTCAAATGAGTCAGAATAGTCATGTT CCCCTTGAGGGATGTCTGACTTGAATGGAGAATTGTTCTTTCCTCTCTTGAATCAGCTCACTAGCTCCCTGATGGTCTGGGTTCAAGGAA ATGGTTAATGAGGTAGAGGCCACTTATACAAGTCCTTGGGATTGTACCATTGCTGTCCACAAACTTAGTATCAACAACACATGCTGTGCC CTGTGAACACTCTCCTCTCACCTATTTCCAGGGTTGGTCTTCCTGAGAAGGGGATGGATGAGGTAACACACAGTTTGGGATACGTATCTG TTGAATGAATGAATAAGTGAAAGGATAATAGTCCTCTGAGGTAAAAATGGCCTTGTCAGAATTTTGAAAATCCAACAGATTCCTATTAAA GCACTCTGTGTACCAATAACATGCATGCATTGTACCAAGTAATCACAATGTGAATTGGTCAATTTATGAGCCTTGCCTACTTTAGAAAAT >86350_86350_5_SRGAP1-TBC1D30_SRGAP1_chr12_64410792_ENST00000543397_TBC1D30_chr12_65258448_ENST00000229088_length(amino acids)=563AA_BP=148 MASLLSLEIRAQLVEQQKCLEQQTEMRVQLLQDLQDFFRKKAEIETEYSRNLEKLAERFMAKTRSTKDHQQYKKDQNLLSPVNCWYLLLN QVRRESKDHATLSDIYLNNVIMRFMQISEDSTRMFKKSKEIAFQLHEDLMKVLNELYTTVYSMAPFPFPQLAELREKYTYNITPFPATVK PTSVSGRHSKARDSDEENDPDDEDAVVNAVGCLGPFSGFLAPELQKYQKQIKEPNEEQSLRSNNIAELSPGAINSCRSEYHAAFNSMMME RMTTDINALKRQYSRIKKKQQQQVHQVYIRADKGPVTSILPSQVNSSPVINHLLLGKKMKMTNRAAKNAVIHIPGHTGGKISPVPYEDLK TKLNSPWRTHIRVHKKNMPRTKSHPGCGDTVGLIDEQNEASKTNGLGAAEAFPSGCTATAGREGSSPEGSTRRTIEGQSPEPVFGDADVD VSAVQAKLGALELNQRDAAAETELRVHPPCQRHCPEPPSAPEENKATSKAPQGSNSKTPIFSPFPSVKPLRKSATARNLGLYGPTERTPT -------------------------------------------------------------- >86350_86350_6_SRGAP1-TBC1D30_SRGAP1_chr12_64410792_ENST00000543397_TBC1D30_chr12_65258448_ENST00000542120_length(transcript)=8336nt_BP=1844nt CTTGCTGTTAATGAACTTGGTTAAACATGGTCAAGTGTATGTATGTATATATTATCAGTACTGGCCTTCTCTATCTAAGAGGAATAGCAA GAAATTTAGAGACATTATTTGGACATTGATTTCTACTAACTCCACTGAATTAGATTCAGCCTTCACTTTTTGGGAAATGCACGGACACTG GGAAAGATGAAATGAAGAAGTTTTCCAGCATGATGTTCTTGTCTTTGGAGCTTAGCCTTACTTAGGTCTTAGAACAAAAACAAGTCGGTA GTTATTAGTTACTGTATCTCATTTTCCAAAACACACGTTTCTTTGTTACAGTCATTTACACATATTTTTGCATGCCACATTTTTGCTTTT GAGCTTTTGCTGAATCACTAAATGACCACCTTTCATGTTCCTAATGTATTAAAATTATCAGAGGATTCTTTGAGGATTAAATGTGTCAGT AAGGGTATTATTTTGAACAATGCGTAAAAGGTGAAGGCCAGCTGAAGAGGCCTTTTTGTTGTGAACAGAATAATATACTGGAATCTGAGG ACTGCACTGTTATGAATGGATTATTTGGCTATGGAAAGAAGTTATTTTTAGGCACAGCATCCCTATAAGCCCTGAAGCTATGTGTTTTAC AAACTAGAAATTATGCACTAAATAAAAATTACCAGATGTCAGTCTCTGTATGTGCCAAATGGCAAATGTGTAATGGTTCAGAGCCTGGAA GAAATGATGCTTATTTCTTTGCCATTCAAACTCAAAAGGGATAGCTGAGGTAGAGTGCTGTTGAAAAAATTGCAGTGTTTCCAGCTACCC AAAGATGTTACGAATTGTTATCTGAAAGGCTTTCATTCTTTCCCCTCATGGCTCGTTGTGTGTTTGTGGCATTACAAATGTAACCCACAT ATTTATTCTAATTTATTACATTCTTTCCTGAGGCTCCTCTTGTTCTTTTAAAGGGTCAGCAGATAACTTATTTTAAGAATCAACCTGGAC ACAGTATTCTAACAAAGGTCCAATACAGAGCTAAATAAATAATAGGAGTCATAGCCAGACACAGTGACTCACGCCTGTAATCCCAACATT TTGGGAGGCCAAGGCGGGTGGATTACCTGGTGGTGCATGCCTGTAGTCTCAGCTACTCAGGAGGCTGAGGCAGGAGAATCACTTGAACCC GGGACGCAGAGGTTACAGTGAACCGAGATTGCGCCACTGCACTCCAGCCTGGGCAACAGAGCGAGACCTCTATCTCAAAAATAAATAAAT AAATACATTTAAAATATATATATATATATATATATATATATATATATATATATATATATATATATATATATTTATATATATTTCGTGACT TATATCTTGCACATACCAGCATACCTCATTAATTTTAATGTAACCATCCATTGGCTTCTCTTCTCTCCTTAGAAATTCGAGCTCAACTGG TAGAACAACAAAAATGCCTGGAGCAGCAAACGGAGATGCGAGTTCAGCTTCTCCAGGATCTGCAAGATTTCTTCCGAAAAAAAGCTGAAA TTGAGACGGAATATTCCCGGAATCTAGAGAAGTTAGCAGAAAGGTTCATGGCAAAAACAAGAAGCACTAAGGATCATCAACAATACAAGA AAGACCAGAACCTGTTGTCTCCAGTGAACTGCTGGTATTTGCTCCTGAACCAAGTAAGGAGAGAAAGCAAAGACCATGCAACCTTGAGTG ACATCTATCTGAACAATGTGATTATGCGGTTCATGCAGATAAGTGAGGATTCTACCAGGATGTTTAAAAAGAGCAAAGAGATTGCATTCC AACTTCATGAGGATTTAATGAAGGTTCTTAATGAGCTTTATACGACTGTTTATTCCATGGCTCCGTTCCCTTTCCCACAATTGGCAGAGT TGAGGGAAAAATACACCTACAACATTACACCGTTCCCAGCCACAGTTAAACCCACCTCAGTTTCTGGACGACATAGTAAGGCCAGAGACA GTGATGAAGAGAATGACCCAGACGATGAGGATGCTGTCGTTAATGCAGTGGGGTGTCTTGGACCTTTTAGTGGGTTCCTGGCTCCTGAAC TGCAGAAGTACCAAAAACAAATTAAAGAGCCAAATGAGGAGCAGAGTCTGAGATCTAATAACATTGCAGAGCTGAGTCCAGGAGCAATCA ATTCCTGTCGAAGTGAATACCATGCAGCTTTTAACAGTATGATGATGGAACGCATGACCACAGATATCAATGCACTGAAGCGGCAGTACT CTCGAATTAAAAAGAAGCAACAGCAGCAGGTTCATCAGGTGTACATCAGGGCAGACAAAGGGCCAGTGACCAGCATTCTCCCGTCTCAGG TAAACAGTTCTCCAGTTATAAACCACCTTCTTTTAGGAAAGAAGATGAAAATGACTAACAGAGCTGCCAAGAATGCTGTCATCCACATCC CTGGTCACACAGGAGGGAAAATATCTCCTGTCCCCTACGAAGACCTTAAGACGAAGCTCAACTCCCCGTGGCGAACTCACATCCGAGTCC ACAAAAAGAACATGCCAAGGACCAAGAGTCATCCGGGCTGTGGGGACACCGTAGGGCTGATAGATGAGCAGAACGAGGCCAGCAAGACCA ATGGGCTGGGGGCAGCAGAGGCATTCCCCTCTGGTTGTACAGCGACAGCTGGGAGAGAAGGCAGCAGCCCTGAAGGCAGTACCAGGAGGA CGATCGAGGGGCAGTCTCCGGAGCCGGTGTTCGGAGATGCTGATGTGGATGTGTCTGCAGTTCAGGCGAAGTTGGGAGCCCTGGAACTGA ACCAGAGGGATGCTGCAGCTGAAACTGAGCTCAGGGTGCACCCACCCTGCCAGCGGCACTGCCCAGAGCCGCCGAGTGCACCCGAAGAAA ACAAAGCCACCAGCAAAGCTCCCCAAGGCAGCAACTCAAAAACCCCCATCTTTAGCCCTTTTCCCAGCGTCAAGCCCCTGCGGAAATCTG CTACTGCCAGGAACTTGGGATTATATGGCCCTACAGAAAGAACCCCAACTGTGCACTTTCCTCAAATGAGTAGGAGCTTCAGCAAACCCG GCGGTGGAAACAGTGGCACTAAAAAACGATGATGTCTCCCCGAAACTTTGTATCTGGACTCACCTTTTCACAGTAGTATAAGGGTTGCAG CTGAATGGCTCTAAAAGAGTTTTATTTGTCCAGTGAAAATGAATAGGTTCAGGGATGAGCAACAGCCCATAAAAAATGGGAACTGGAAGT TTTATAATAGGAGTTAGAACAGGGCTGTTTTCCCAGCTACTTGCTAACTGACGAAGTGGATTCTTGTGGCAAAATAAATATTGTGGTTTT ATAGTGTGAAGTTTTCCCAATTTTTCATTGTGAGCTGTTTAAAAAAGACTATATCTAGATTGTTAACTCTCGTCCATCCTTCTGTTCTGG GGGCCTTCAGAGTCCCTGTGACAGCACCCCCAAACCTTCCAGTTCTCTGGGTGTTACTAATACTCAAGCATGCACATACCAGCTTGCTAG GACAGAAACTGTAAAAAGAAAGTAAGTTTCTTCGTTACAAAAAACTTCCTGATTTTCCTTTTCATGCTTTACGGAGGGGATTGTGTCGTG TGAGATTTCCCACAGTACCAGTTTCAAATTTTTTTTTTATTCTTATGCTAAATCATAGGAGAAAAATCTAGATAGCCTTTCTTTAACTGT CTATTTCTACCTGCAAAATGAAGAAAACCTTTCATCTGTTGAAATTTCAATCGATAACCCAGCTGAAGATCTTATGCACAGGACACACTT GGCATATGCTTTACGCAGTTGCTCCGGACAGCTTGCTCGCGCCACTGAGCTTTTCCTGAGGTTTGTGTTCGCCTCTCAAGGAGAGCTTTG ATCCTCAGTGGTACGGATGACTTGATGGGCTCCATGCGGAGCCTGGCCTGCATCCCCCACCACACAGCTCACTCACCCACCAGCTCTAGA CTGCAGACGCACAAGGCCTCTGCTCAGAAGCCAGAACACAGCACCTGTGACTCTGTTACTTGAATTTTGTGCTTTTTGATTGGAGTCCTT TGTTGAGTACTTTGTTAATTGAACACTGCCTTTCTCTGGAGAAGGCCCCAGTGCTTTCTAGCTCCCTCTCACTCCTGCCCTTTCTAGCTC TCTCTCACCCAGCGGGTCAGGGATAGCACCTCTTGTCTCCACTATGCAGATGGGAACTCTGAGCCACACAGAGGTGAAGTAGCACTTCAG TTACTCAAGGTCAGTACTCTCGGTATTCCAAGTGACTTAGCCACATTTCCTTCAGTGCAATAGGTGGGTTTAATGCTCTTTGTACACAGA TGTATTGGCTACATAGCGTGTAAAAACCAAGACTGGGAAGCCATTCACTAAAATCCCTCCTGACTCAAAGGACCTGTCTCCAGATGGTAC AGAGTCCCTTGATGGCATTTTACAAAACCAGCTCTGACTTCCTTATCCTGAACAGGGAGTTTATTTTAAAAATGCTTCATGCACCTGTTA TTTGGCTGAACAGAAGGCTCACTCCTCAATCCCCTTCTCCTCGCCATCATTAGAGGAATAGACTCAGCCTTCATGTTTGTCTCTGGAAGA CGATTGGCGATACTTGCAGGAATATTGTTGATGCAGCCAATATTAATTTGAGCTAATGGATTGTTAATTCTGAAACGAAAACTGTAACTG TAGAGCAGGCTTTTACTATGAGAGGTACTACTTTTTATAATAGAGAATGTGGTTGTGTGGGCTTTTTTTGAACAGAAAACACAACAATGA CCTATACCGTGAGAAAAGCCATTTTATCTTCTTCGTGGTATTTTTACCCCCAAAGGAACTGAAGATGGAAAATATGACTAATAAGTTATT GCAGTTTTGGTCTTGAATTCTGTGCCATCTGAAGTTAGCATCCAGCTTCTTAAAAAGCAGCCACGCCTACAGCCTGTTTTTTGGGAAGGC TGTAGGTGGAGAGATGGGCTTATTTTGCATACCACCCTCAGGGCCCAGAGACCCACTGCATTTTCCAAAGTTAAGCAAATGACACCATTT TCTTCCATCAGCTAAACTTTACAGATAATAGTGTTTCCACCTCATATCCTTTTCTTTGCCCCTTCTCAAATGAGTCAGAATAGTCATGTT CCCCTTGAGGGATGTCTGACTTGAATGGAGAATTGTTCTTTCCTCTCTTGAATCAGCTCACTAGCTCCCTGATGGTCTGGGTTCAAGGAA ATGGTTAATGAGGTAGAGGCCACTTATACAAGTCCTTGGGATTGTACCATTGCTGTCCACAAACTTAGTATCAACAACACATGCTGTGCC CTGTGAACACTCTCCTCTCACCTATTTCCAGGGTTGGTCTTCCTGAGAAGGGGATGGATGAGGTAACACACAGTTTGGGATACGTATCTG TTGAATGAATGAATAAGTGAAAGGATAATAGTCCTCTGAGGTAAAAATGGCCTTGTCAGAATTTTGAAAATCCAACAGATTCCTATTAAA GCACTCTGTGTACCAATAACATGCATGCATTGTACCAAGTAATCACAATGTGAATTGGTCAATTTATGAGCCTTGCCTACTTTAGAAAAT AAAGAAACCTGCAGTAGCCTCTACCACACAGCATGTACAAAGACCAGTATGGACTTGCTATCTTCCCTATGTATTGGACACTGTATGCAA ACACCAGAAGTACTTAACAAGTAGTGGTTTCTTGATTTTTAGATATGTCTGTAGCCTCTTAGCCCTTTTGCCGGGAATCAACTCATTCTG ATGCCTCTGCACCTCAGTTCCTCTTACAAAAGCCTCCAGATGATCTAAATCTAGTTAGCAATGTCAGCCTGTGGACTGCAGCTGTTTGGG ACATTGTATTCCTTTGTTTGTCTCTTGTTGTTCTGAAGGATTGTATTGATCACAAAGCTATATGCATAAAGATTCTCATTGTTGTAACTG TTCTGCCATTTTCTGAGTGCAAGCATGGAACACTGTTGTGACAGTCCCTTCTCCCTTCTTCCTTCTTCCTTCACCCCCAACCCCAGACCC CCCTTGGTCACATGAACCAGGGAAACAGCCCAATAAGCTCTATCTCCCCCAGTCTAATCGCTGGGTTGCAGGGTGGCCTGTGACCTGCCC AGCATTTGCAGACTCGCTGGTTCCTGAATATGAGTAAGCACAGAGTTTACCTAGAGAGTTTACCTAAAATTAACCTTTAGATCTACTATT TATTTTTGTCTTAATAAAATGAACAATAAATATAGTTTAGCTGCATGGCATTAAGGATTCTGTATGAATAGATGTATAGTTGCTGCCATC TCCCCATATAAAAACTCTCTTTACATCGTTTCTGAGCCACTTTCTTTGCTGTCTGCAGCATTTAAAATATATTATTTTTCCTAATTAGAA AAGTCACAGGTTTTAGAAAATTGGGAAAACAAAAAGAGCATAAAGAATCATCAATACTCTGATATAGATATAGATCTTTCCAGTACGTTT GTGTATGTGTGTACACGCCATTATCTACAAAAAAGTTATGTTGAACATGGTAGTTTAAGCTGTCTTTCTGGTAAATGCTCTTATACAATA TGATTTTTAGTGACTAATATTCCCTAATGTGTTCATGCCAGAATTCACATAACCAGTACCTTGTCAAATAGGAGGTTTCTGATTAGATAG TAGTAGAGACAGTATCCTGTTACATGTATGTACATAGCCCGAATTATTTTCTTAGGATATGCGTATAGAAGTGGAGTTGAAGGGTCAGGA AATATGTCCATTTTTAAGATACATATATCTCCAAATTGCCATTCTTAAAGGTTGGAGTTATACAAGTAGTGAATGAGAATGCCTGCTTCT CTACATCCTGGAAGAGGCAGCAGTCTCTTTCCTTTTTTTTCCTTTCTATGACTTCTAGTGTGGAAGTGCCAACAGAAGTGTTTTAGAAGC AGTGATAATGAACACTCATAACACCCATACCTCATTCCTGACTTTTAAAAGAAGCATTAAGTAAGATGTTGAGGTTTCTGGTAGGTGCCT ATTATTAGGTTAAGAAAATTCCCTTTTATTCTTTGCTTGCTAAGAGTTTTCTTCATCAACAGGTATTGAATTTCATAAAAAGAACTTTAA TTGTATCTTTTGAGAAGGGAATAGTACTTGAGACTTGGTATCCTGAACTCAAAGAAATAGCCATTACTAGGTTTTGTCAAAGAATACCAG ATATTTTAGAGTTGGAAGTTATGCAGTAAAAGCTTTATGTGCAAATGTTCATTGAAGTATTAAATGTACTAATGGAAACCTGAAAACAAT ATAAACATCTGGGAATAGGGGAGATGTTTGGATGAATTATGATTCATCCCCAGGATGGAAATGTGAAGGCCGGTGAGTATTTGGACCATT GAAGTGGGAGTTATCTGTTATCCACATCAGGCAGCTCAGAGTAAAGTCAGCAAGTCTACAGTCATAGAGCCACCAGGATACAGTGATGGA TGGGAGGCCTTTGCTGGACAGTGGCTGAAGGCAGAACTGTTGGAGTGGTTCTTCCACAAAGGCAGCCAGTGCTCACCTGAATGGGGACTG GTACTGTAGGTATTGGGTCAGCTTTCATGCCGTTCCCTGCTGGCCATCTCCCAATGCTGAATGTCTGACTCAGTTCAGGCTGCTGTAACA AAGTACCATAGACTGAGGTGGCTTAAACACAGACATTTCTTTCTCACAGTTCTGGAGGCTGAGAAGTCAAAGATCAACGTGTCTGCAAAT TTGGTATCTGGTGAGGAAGGGCCCTCTTCCTGGTTTGCAGATGGCTACCTTCTCACTGTGTCCTCACACAATGGAGAAAGGGAGTATGTT TTGGTCTCTTCCTCTTCTGATAAGGGCACTAACCTCATCATGAGGGTCCCATCCTCCTGGTGTCATCTAAACCTAATTACCTCCCAATGG CCCCGCCTTCAAATACCATCACGTTGAAGGTTGCTTCCTTCCTGGTCGTTTGCTCTGGTGAGACCAAATGACCTGCAAAGTGTCACTTGA TTCCATTCTCTCCATCCCTTCCATCCCAGGCAATCTTTATCTAGCTACACCAACCTGTGCCCCAGGGGCTTCAAGAGTTGTTGTTGTTTT AACATTAAAAAACCAGAAAGTTCACTTGTTTCTTAGTGTTTACATCCTTGCTATAACAATTCTAGTTTTCCTTTAGGCAATGCTGATCAC TGGGAAGGAGGTGGATCAATTCTCCTATGGGACCAACAGTTTTCTGGGAAGAAACTTCCTGATACCTCAGCCTAGGAATCTCCCTATCCC >86350_86350_6_SRGAP1-TBC1D30_SRGAP1_chr12_64410792_ENST00000543397_TBC1D30_chr12_65258448_ENST00000542120_length(amino acids)=563AA_BP=148 MASLLSLEIRAQLVEQQKCLEQQTEMRVQLLQDLQDFFRKKAEIETEYSRNLEKLAERFMAKTRSTKDHQQYKKDQNLLSPVNCWYLLLN QVRRESKDHATLSDIYLNNVIMRFMQISEDSTRMFKKSKEIAFQLHEDLMKVLNELYTTVYSMAPFPFPQLAELREKYTYNITPFPATVK PTSVSGRHSKARDSDEENDPDDEDAVVNAVGCLGPFSGFLAPELQKYQKQIKEPNEEQSLRSNNIAELSPGAINSCRSEYHAAFNSMMME RMTTDINALKRQYSRIKKKQQQQVHQVYIRADKGPVTSILPSQVNSSPVINHLLLGKKMKMTNRAAKNAVIHIPGHTGGKISPVPYEDLK TKLNSPWRTHIRVHKKNMPRTKSHPGCGDTVGLIDEQNEASKTNGLGAAEAFPSGCTATAGREGSSPEGSTRRTIEGQSPEPVFGDADVD VSAVQAKLGALELNQRDAAAETELRVHPPCQRHCPEPPSAPEENKATSKAPQGSNSKTPIFSPFPSVKPLRKSATARNLGLYGPTERTPT -------------------------------------------------------------- |
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Fusion Gene PPI Analysis for SRGAP1-TBC1D30 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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Related Drugs for SRGAP1-TBC1D30 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.8 2021-05-08) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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Related Diseases for SRGAP1-TBC1D30 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
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