FusionGDB Logo

Home

Download

Statistics

Examples

Help

Contact
Center for Computational Systems Medicine
leaf

Fusion Gene Summary

leaf

Fusion Gene ORF analysis

leaf

Fusion Genomic Features

leaf

Fusion Protein Features

leaf

Fusion Gene Sequence

leaf

Fusion Gene PPI analysis

leaf

Related Drugs

leaf

Related Diseases

Fusion gene:SRRT-GAPDH (FusionGDB2 ID:86572)

Fusion Gene Summary for SRRT-GAPDH

check button Fusion gene summary
Fusion gene informationFusion gene name: SRRT-GAPDH
Fusion gene ID: 86572
HgeneTgene
Gene symbol

SRRT

GAPDH

Gene ID

51593

2597

Gene nameserrate, RNA effector moleculeglyceraldehyde-3-phosphate dehydrogenase
SynonymsARS2|ASR2|serrateG3PD|GAPD|HEL-S-162eP
Cytomap

7q22.1

12p13.31

Type of geneprotein-codingprotein-coding
Descriptionserrate RNA effector molecule homologarsenate resistance protein 2arsenate resistance protein ARS2arsenite resistance proteinarsenite-resistance protein 2glyceraldehyde-3-phosphate dehydrogenaseOCAS, p38 componentOct1 coactivator in S phase, 38 Kd componentaging-associated gene 9 proteinepididymis secretory sperm binding protein Li 162ePpeptidyl-cysteine S-nitrosylase GAPDH
Modification date2020031320200327
UniProtAcc.

P04406

Ensembl transtripts involved in fusion geneENST00000347433, ENST00000388793, 
ENST00000432932, ENST00000457580, 
ENST00000396856, ENST00000396858, 
ENST00000396859, ENST00000229239, 
ENST00000396861, 
Fusion gene scores* DoF score9 X 8 X 3=21627 X 29 X 8=6264
# samples 1031
** MAII scorelog2(10/216*10)=-1.11103131238874
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(31/6264*10)=-4.3367440920168
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: SRRT [Title/Abstract] AND GAPDH [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointSRRT(100484540)-GAPDH(6647322), # samples:1
Anticipated loss of major functional domain due to fusion event.SRRT-GAPDH seems lost the major protein functional domain in Hgene partner, which is a essential gene due to the frame-shifted ORF.
SRRT-GAPDH seems lost the major protein functional domain in Tgene partner, which is a cell metabolism gene due to the frame-shifted ORF.
SRRT-GAPDH seems lost the major protein functional domain in Tgene partner, which is a essential gene due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
TgeneGAPDH

GO:0010951

negative regulation of endopeptidase activity

22832495

TgeneGAPDH

GO:0017148

negative regulation of translation

23071094

TgeneGAPDH

GO:0031640

killing of cells of other organism

22832495

TgeneGAPDH

GO:0050715

positive regulation of cytokine secretion

22832495

TgeneGAPDH

GO:0050832

defense response to fungus

22832495

TgeneGAPDH

GO:0051873

killing by host of symbiont cells

22832495

TgeneGAPDH

GO:0052501

positive regulation by organism of apoptotic process in other organism involved in symbiotic interaction

22832495

TgeneGAPDH

GO:0061844

antimicrobial humoral immune response mediated by antimicrobial peptide

22832495

TgeneGAPDH

GO:0071346

cellular response to interferon-gamma

15479637


check buttonFusion gene breakpoints across SRRT (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across GAPDH (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChiTaRS5.0N/ABF820683SRRTchr7

100484540

+GAPDHchr12

6647322

+


Top

Fusion Gene ORF analysis for SRRT-GAPDH

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
Frame-shiftENST00000347433ENST00000396856SRRTchr7

100484540

+GAPDHchr12

6647322

+
Frame-shiftENST00000347433ENST00000396858SRRTchr7

100484540

+GAPDHchr12

6647322

+
Frame-shiftENST00000347433ENST00000396859SRRTchr7

100484540

+GAPDHchr12

6647322

+
Frame-shiftENST00000388793ENST00000396856SRRTchr7

100484540

+GAPDHchr12

6647322

+
Frame-shiftENST00000388793ENST00000396858SRRTchr7

100484540

+GAPDHchr12

6647322

+
Frame-shiftENST00000388793ENST00000396859SRRTchr7

100484540

+GAPDHchr12

6647322

+
Frame-shiftENST00000432932ENST00000396856SRRTchr7

100484540

+GAPDHchr12

6647322

+
Frame-shiftENST00000432932ENST00000396858SRRTchr7

100484540

+GAPDHchr12

6647322

+
Frame-shiftENST00000432932ENST00000396859SRRTchr7

100484540

+GAPDHchr12

6647322

+
Frame-shiftENST00000457580ENST00000396856SRRTchr7

100484540

+GAPDHchr12

6647322

+
Frame-shiftENST00000457580ENST00000396858SRRTchr7

100484540

+GAPDHchr12

6647322

+
Frame-shiftENST00000457580ENST00000396859SRRTchr7

100484540

+GAPDHchr12

6647322

+
In-frameENST00000347433ENST00000229239SRRTchr7

100484540

+GAPDHchr12

6647322

+
In-frameENST00000347433ENST00000396861SRRTchr7

100484540

+GAPDHchr12

6647322

+
In-frameENST00000388793ENST00000229239SRRTchr7

100484540

+GAPDHchr12

6647322

+
In-frameENST00000388793ENST00000396861SRRTchr7

100484540

+GAPDHchr12

6647322

+
In-frameENST00000432932ENST00000229239SRRTchr7

100484540

+GAPDHchr12

6647322

+
In-frameENST00000432932ENST00000396861SRRTchr7

100484540

+GAPDHchr12

6647322

+
In-frameENST00000457580ENST00000229239SRRTchr7

100484540

+GAPDHchr12

6647322

+
In-frameENST00000457580ENST00000396861SRRTchr7

100484540

+GAPDHchr12

6647322

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000457580SRRTchr7100484540+ENST00000229239GAPDHchr126647322+213119162201902560
ENST00000457580SRRTchr7100484540+ENST00000396861GAPDHchr126647322+211919162201902560
ENST00000388793SRRTchr7100484540+ENST00000229239GAPDHchr126647322+212819132201899559
ENST00000388793SRRTchr7100484540+ENST00000396861GAPDHchr126647322+211619132201899559
ENST00000432932SRRTchr7100484540+ENST00000229239GAPDHchr126647322+206918541611840559
ENST00000432932SRRTchr7100484540+ENST00000396861GAPDHchr126647322+205718541611840559
ENST00000347433SRRTchr7100484540+ENST00000229239GAPDHchr126647322+206918541581840560
ENST00000347433SRRTchr7100484540+ENST00000396861GAPDHchr126647322+205718541581840560

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000457580ENST00000229239SRRTchr7100484540+GAPDHchr126647322+0.0107733210.9892267
ENST00000457580ENST00000396861SRRTchr7100484540+GAPDHchr126647322+0.0109043080.98909575
ENST00000388793ENST00000229239SRRTchr7100484540+GAPDHchr126647322+0.0106524510.9893476
ENST00000388793ENST00000396861SRRTchr7100484540+GAPDHchr126647322+0.0107819370.9892181
ENST00000432932ENST00000229239SRRTchr7100484540+GAPDHchr126647322+0.011584660.98841536
ENST00000432932ENST00000396861SRRTchr7100484540+GAPDHchr126647322+0.0117368340.9882632
ENST00000347433ENST00000229239SRRTchr7100484540+GAPDHchr126647322+0.0118003370.9881997
ENST00000347433ENST00000396861SRRTchr7100484540+GAPDHchr126647322+0.0119556450.9880443

Top

Fusion Genomic Features for SRRT-GAPDH


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

Top

Fusion Protein Features for SRRT-GAPDH


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr7:100484540/chr12:6647322)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
.GAPDH

P04406

FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Has both glyceraldehyde-3-phosphate dehydrogenase and nitrosylase activities, thereby playing a role in glycolysis and nuclear functions, respectively. Participates in nuclear events including transcription, RNA transport, DNA replication and apoptosis. Nuclear functions are probably due to the nitrosylase activity that mediates cysteine S-nitrosylation of nuclear target proteins such as SIRT1, HDAC2 and PRKDC. Modulates the organization and assembly of the cytoskeleton. Facilitates the CHP1-dependent microtubule and membrane associations through its ability to stimulate the binding of CHP1 to microtubules (By similarity). Glyceraldehyde-3-phosphate dehydrogenase is a key enzyme in glycolysis that catalyzes the first step of the pathway by converting D-glyceraldehyde 3-phosphate (G3P) into 3-phospho-D-glyceroyl phosphate. Component of the GAIT (gamma interferon-activated inhibitor of translation) complex which mediates interferon-gamma-induced transcript-selective translation inhibition in inflammation processes. Upon interferon-gamma treatment assembles into the GAIT complex which binds to stem loop-containing GAIT elements in the 3'-UTR of diverse inflammatory mRNAs (such as ceruplasmin) and suppresses their translation. {ECO:0000250, ECO:0000269|PubMed:11724794, ECO:0000269|PubMed:23071094, ECO:0000269|PubMed:3170585}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneGAPDHchr7:100484540chr12:6647322ENST0000022923909245_2500336.0Motif[IL]-x-C-x-x-[DE] motif
TgeneGAPDHchr7:100484540chr12:6647322ENST0000039685808245_2500294.0Motif[IL]-x-C-x-x-[DE] motif
TgeneGAPDHchr7:100484540chr12:6647322ENST0000039685908245_2500336.0Motif[IL]-x-C-x-x-[DE] motif
TgeneGAPDHchr7:100484540chr12:6647322ENST0000039686109245_2500336.0Motif[IL]-x-C-x-x-[DE] motif
TgeneGAPDHchr7:100484540chr12:6647322ENST000002292390913_140336.0Nucleotide bindingNAD
TgeneGAPDHchr7:100484540chr12:6647322ENST000003968580813_140294.0Nucleotide bindingNAD
TgeneGAPDHchr7:100484540chr12:6647322ENST000003968590813_140336.0Nucleotide bindingNAD
TgeneGAPDHchr7:100484540chr12:6647322ENST000003968610913_140336.0Nucleotide bindingNAD
TgeneGAPDHchr7:100484540chr12:6647322ENST0000022923909151_1530336.0RegionGlyceraldehyde 3-phosphate binding
TgeneGAPDHchr7:100484540chr12:6647322ENST0000022923909211_2120336.0RegionGlyceraldehyde 3-phosphate binding
TgeneGAPDHchr7:100484540chr12:6647322ENST0000039685808151_1530294.0RegionGlyceraldehyde 3-phosphate binding
TgeneGAPDHchr7:100484540chr12:6647322ENST0000039685808211_2120294.0RegionGlyceraldehyde 3-phosphate binding
TgeneGAPDHchr7:100484540chr12:6647322ENST0000039685908151_1530336.0RegionGlyceraldehyde 3-phosphate binding
TgeneGAPDHchr7:100484540chr12:6647322ENST0000039685908211_2120336.0RegionGlyceraldehyde 3-phosphate binding
TgeneGAPDHchr7:100484540chr12:6647322ENST0000039686109151_1530336.0RegionGlyceraldehyde 3-phosphate binding
TgeneGAPDHchr7:100484540chr12:6647322ENST0000039686109211_2120336.0RegionGlyceraldehyde 3-phosphate binding

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneSRRTchr7:100484540chr12:6647322ENST00000347433+12010_820877.0Compositional biasNote=Arg-rich
HgeneSRRTchr7:100484540chr12:6647322ENST00000347433+120258_4020877.0Compositional biasNote=Glu-rich
HgeneSRRTchr7:100484540chr12:6647322ENST00000347433+120760_8280877.0Compositional biasNote=Pro-rich
HgeneSRRTchr7:100484540chr12:6647322ENST00000388793+12010_820876.0Compositional biasNote=Arg-rich
HgeneSRRTchr7:100484540chr12:6647322ENST00000388793+120258_4020876.0Compositional biasNote=Glu-rich
HgeneSRRTchr7:100484540chr12:6647322ENST00000388793+120760_8280876.0Compositional biasNote=Pro-rich
HgeneSRRTchr7:100484540chr12:6647322ENST00000432932+12010_820872.0Compositional biasNote=Arg-rich
HgeneSRRTchr7:100484540chr12:6647322ENST00000432932+120258_4020872.0Compositional biasNote=Glu-rich
HgeneSRRTchr7:100484540chr12:6647322ENST00000432932+120760_8280872.0Compositional biasNote=Pro-rich
HgeneSRRTchr7:100484540chr12:6647322ENST00000457580+12010_820873.0Compositional biasNote=Arg-rich
HgeneSRRTchr7:100484540chr12:6647322ENST00000457580+120258_4020873.0Compositional biasNote=Glu-rich
HgeneSRRTchr7:100484540chr12:6647322ENST00000457580+120760_8280873.0Compositional biasNote=Pro-rich


Top

Fusion Gene Sequence for SRRT-GAPDH


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>86572_86572_1_SRRT-GAPDH_SRRT_chr7_100484540_ENST00000347433_GAPDH_chr12_6647322_ENST00000229239_length(transcript)=2069nt_BP=1854nt
GTTCGCCTCTCTTCGGCCCTCTACTCAAGAGCTCCGTCTCCGTCTCGCCCTCCTCGAAGTCCTCGTCGCGCGCCCGCGACCCAGGTCGCC
CTGAAATCTAGCCCGTCCGAGCGCGAGTCCAACGCCGCGGCCGCACCAAGGCCCCCTCAGACCGTGCCATGGGTGACAGTGATGACGAGT
ACGATCGAAGGCGCAGGGACAAGTTCAGAAGAGAGCGCAGCGACTACGACCGTTCCCGCGAGAGAGATGAAAGACGTCGAGGGGACGATT
GGAATGACAGAGAGTGGGACCGTGGCCGTGAGCGCCGTAGTCGGGGTGAATATCGGGACTATGACCGGAATCGGCGAGAGCGCTTCTCGC
CACCTCGCCACGAACTCAGCCCGCCACAGAAGCGCATGAGGAGAGACTGGGATGAGCACAGCTCTGACCCATACCACAGTGGCTATGAGA
TGCCCTATGCTGGGGGGGGTGGGGGCCCAACTTATGGCCCCCCTCAGCCCTGGGGCCACCCTGACGTCCACATCATGCAGCACCATGTCC
TGCCTATCCAGGCCAGGCTGGGCAGCATTGCAGAGATTGACCTGGGTGTGCCGCCGCCCGTGATGAAGACCTTCAAGGAGTTTCTCCTCT
CCCTGGATGACTCGGTGGATGAGACGGAGGCCGTCAAGCGCTATAATGACTACAAGCTGGATTTCCGGAGGCAACAGATGCAGGATTTCT
TCCTGGCGCACAAAGATGAGGAGTGGTTTCGGTCTAAGTACCACCCAGATGAGGTGGGGAAGCGTCGGCAGGAGGCCCGGGGGGCCCTGC
AAAACCGACTGAGGGTCTTCCTGTCCCTCATGGAGACTGGCTGGTTTGATAACCTTCTCCTGGACATAGACAAAGCTGATGCCATTGTCA
AGATGCTGGATGCAGCCGTGATTAAGATGGAAGGAGGCACGGAGAATGATCTTCGCATCCTGGAGCAGGAGGAGGAGGAGGAGCAGGCAG
GAAAGCCTGGGGAGCCCAGCAAGAAAGAAGAAGGACGGGCTGGAGCAGGCCTAGGGGACGGGGAGCGCAAAACCAACGACAAGGATGAGA
AGAAGGAAGACGGCAAGCAGGCTGAGAATGACAGTTCTAATGATGACAAAACAAAGAAGTCGGAGGGTGATGGGGACAAGGAAGAGAAGA
AAGAAGACTCCGAGAAGGAAGCCAAAAAGAGTAGCAAGAAGCGGAACCGGAAGCACAGTGGTGACGACAGCTTTGACGAGGGCAGCGTGT
CAGAGTCTGAGTCGGAGTCAGAGAGCGGCCAGGCTGAGGAGGAGAAGGAGGAGGCCGAAGAAGCGCTCAAGGAGAAGGAGAAGCCCAAGG
AAGAAGAATGGGAGAAGCCCAAGGACGCCGCGGGGCTGGAGTGCAAGCCGCGGCCGCTGCATAAGACCTGCTCCCTCTTCATGCGCAACA
TCGCGCCCAACATCTCCCGGGCCGAGATCATCTCCCTTTGTAAAAGGTACCCAGGCTTTATGCGGGTGGCGCTCTCAGAGCCCCAGCCAG
AGAGGAGGTTTTTCCGTCGTGGCTGGGTGACCTTCGACCGCAGTGTTAACATTAAAGAGATCTGTTGGAACCTGCAGAACATCCGTCTCC
GGGAGTGTGAGCTGAGCCCTGGTGTGAACAGGGACCTGACCCGGCGCGTTCGCAACATCAACGGCATCACCCAGCACAAGCAGATTGTGC
GCAACGACATCAAGCTGGCGGCCAAGCTGATCCACACGCTGGATGACAGGACACAGCTTTGGGCCTCAGAACCAGGGACGCCTCCCCTGC
CCACGAGGGAACCCGGCAGAGATCAACGTGGAGCGGGATGAGAAGTTGATTAAGCCTCCAAGGAGTAAGACCCCTGGACCACCAGCCCCA
GCAAGAGCACAAGAGGAAGAGAGAGACCCTCACTGCTGGGGAGTCCCTGCCACACTCAGTCCCCCACCACACTGAATCTCCCCTCCTCAC

>86572_86572_1_SRRT-GAPDH_SRRT_chr7_100484540_ENST00000347433_GAPDH_chr12_6647322_ENST00000229239_length(amino acids)=560AA_BP=
MGDSDDEYDRRRRDKFRRERSDYDRSRERDERRRGDDWNDREWDRGRERRSRGEYRDYDRNRRERFSPPRHELSPPQKRMRRDWDEHSSD
PYHSGYEMPYAGGGGGPTYGPPQPWGHPDVHIMQHHVLPIQARLGSIAEIDLGVPPPVMKTFKEFLLSLDDSVDETEAVKRYNDYKLDFR
RQQMQDFFLAHKDEEWFRSKYHPDEVGKRRQEARGALQNRLRVFLSLMETGWFDNLLLDIDKADAIVKMLDAAVIKMEGGTENDLRILEQ
EEEEEQAGKPGEPSKKEEGRAGAGLGDGERKTNDKDEKKEDGKQAENDSSNDDKTKKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDD
SFDEGSVSESESESESGQAEEEKEEAEEALKEKEKPKEEEWEKPKDAAGLECKPRPLHKTCSLFMRNIAPNISRAEIISLCKRYPGFMRV
ALSEPQPERRFFRRGWVTFDRSVNIKEICWNLQNIRLRECELSPGVNRDLTRRVRNINGITQHKQIVRNDIKLAAKLIHTLDDRTQLWAS

--------------------------------------------------------------
>86572_86572_2_SRRT-GAPDH_SRRT_chr7_100484540_ENST00000347433_GAPDH_chr12_6647322_ENST00000396861_length(transcript)=2057nt_BP=1854nt
GTTCGCCTCTCTTCGGCCCTCTACTCAAGAGCTCCGTCTCCGTCTCGCCCTCCTCGAAGTCCTCGTCGCGCGCCCGCGACCCAGGTCGCC
CTGAAATCTAGCCCGTCCGAGCGCGAGTCCAACGCCGCGGCCGCACCAAGGCCCCCTCAGACCGTGCCATGGGTGACAGTGATGACGAGT
ACGATCGAAGGCGCAGGGACAAGTTCAGAAGAGAGCGCAGCGACTACGACCGTTCCCGCGAGAGAGATGAAAGACGTCGAGGGGACGATT
GGAATGACAGAGAGTGGGACCGTGGCCGTGAGCGCCGTAGTCGGGGTGAATATCGGGACTATGACCGGAATCGGCGAGAGCGCTTCTCGC
CACCTCGCCACGAACTCAGCCCGCCACAGAAGCGCATGAGGAGAGACTGGGATGAGCACAGCTCTGACCCATACCACAGTGGCTATGAGA
TGCCCTATGCTGGGGGGGGTGGGGGCCCAACTTATGGCCCCCCTCAGCCCTGGGGCCACCCTGACGTCCACATCATGCAGCACCATGTCC
TGCCTATCCAGGCCAGGCTGGGCAGCATTGCAGAGATTGACCTGGGTGTGCCGCCGCCCGTGATGAAGACCTTCAAGGAGTTTCTCCTCT
CCCTGGATGACTCGGTGGATGAGACGGAGGCCGTCAAGCGCTATAATGACTACAAGCTGGATTTCCGGAGGCAACAGATGCAGGATTTCT
TCCTGGCGCACAAAGATGAGGAGTGGTTTCGGTCTAAGTACCACCCAGATGAGGTGGGGAAGCGTCGGCAGGAGGCCCGGGGGGCCCTGC
AAAACCGACTGAGGGTCTTCCTGTCCCTCATGGAGACTGGCTGGTTTGATAACCTTCTCCTGGACATAGACAAAGCTGATGCCATTGTCA
AGATGCTGGATGCAGCCGTGATTAAGATGGAAGGAGGCACGGAGAATGATCTTCGCATCCTGGAGCAGGAGGAGGAGGAGGAGCAGGCAG
GAAAGCCTGGGGAGCCCAGCAAGAAAGAAGAAGGACGGGCTGGAGCAGGCCTAGGGGACGGGGAGCGCAAAACCAACGACAAGGATGAGA
AGAAGGAAGACGGCAAGCAGGCTGAGAATGACAGTTCTAATGATGACAAAACAAAGAAGTCGGAGGGTGATGGGGACAAGGAAGAGAAGA
AAGAAGACTCCGAGAAGGAAGCCAAAAAGAGTAGCAAGAAGCGGAACCGGAAGCACAGTGGTGACGACAGCTTTGACGAGGGCAGCGTGT
CAGAGTCTGAGTCGGAGTCAGAGAGCGGCCAGGCTGAGGAGGAGAAGGAGGAGGCCGAAGAAGCGCTCAAGGAGAAGGAGAAGCCCAAGG
AAGAAGAATGGGAGAAGCCCAAGGACGCCGCGGGGCTGGAGTGCAAGCCGCGGCCGCTGCATAAGACCTGCTCCCTCTTCATGCGCAACA
TCGCGCCCAACATCTCCCGGGCCGAGATCATCTCCCTTTGTAAAAGGTACCCAGGCTTTATGCGGGTGGCGCTCTCAGAGCCCCAGCCAG
AGAGGAGGTTTTTCCGTCGTGGCTGGGTGACCTTCGACCGCAGTGTTAACATTAAAGAGATCTGTTGGAACCTGCAGAACATCCGTCTCC
GGGAGTGTGAGCTGAGCCCTGGTGTGAACAGGGACCTGACCCGGCGCGTTCGCAACATCAACGGCATCACCCAGCACAAGCAGATTGTGC
GCAACGACATCAAGCTGGCGGCCAAGCTGATCCACACGCTGGATGACAGGACACAGCTTTGGGCCTCAGAACCAGGGACGCCTCCCCTGC
CCACGAGGGAACCCGGCAGAGATCAACGTGGAGCGGGATGAGAAGTTGATTAAGCCTCCAAGGAGTAAGACCCCTGGACCACCAGCCCCA
GCAAGAGCACAAGAGGAAGAGAGAGACCCTCACTGCTGGGGAGTCCCTGCCACACTCAGTCCCCCACCACACTGAATCTCCCCTCCTCAC

>86572_86572_2_SRRT-GAPDH_SRRT_chr7_100484540_ENST00000347433_GAPDH_chr12_6647322_ENST00000396861_length(amino acids)=560AA_BP=
MGDSDDEYDRRRRDKFRRERSDYDRSRERDERRRGDDWNDREWDRGRERRSRGEYRDYDRNRRERFSPPRHELSPPQKRMRRDWDEHSSD
PYHSGYEMPYAGGGGGPTYGPPQPWGHPDVHIMQHHVLPIQARLGSIAEIDLGVPPPVMKTFKEFLLSLDDSVDETEAVKRYNDYKLDFR
RQQMQDFFLAHKDEEWFRSKYHPDEVGKRRQEARGALQNRLRVFLSLMETGWFDNLLLDIDKADAIVKMLDAAVIKMEGGTENDLRILEQ
EEEEEQAGKPGEPSKKEEGRAGAGLGDGERKTNDKDEKKEDGKQAENDSSNDDKTKKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDD
SFDEGSVSESESESESGQAEEEKEEAEEALKEKEKPKEEEWEKPKDAAGLECKPRPLHKTCSLFMRNIAPNISRAEIISLCKRYPGFMRV
ALSEPQPERRFFRRGWVTFDRSVNIKEICWNLQNIRLRECELSPGVNRDLTRRVRNINGITQHKQIVRNDIKLAAKLIHTLDDRTQLWAS

--------------------------------------------------------------
>86572_86572_3_SRRT-GAPDH_SRRT_chr7_100484540_ENST00000388793_GAPDH_chr12_6647322_ENST00000229239_length(transcript)=2128nt_BP=1913nt
GGGTGACGCAGGCGCAGCGCGGGCTGCGCGCGCTACTGCCCATCCCCGGTTGTCCCACTTTTGTTCGCCTCTCTTCGGCCCTCTACTCAA
GAGCTCCGTCTCCGTCTCGCCCTCCTCGAAGTCCTCGTCGCGCGCCCGCGACCCAGGTCGCCCTGAAATCTAGCCCGTCCGAGCGCGAGT
CCAACGCCGCGGCCGCACCAAGGCCCCCTCAGACCGTGCCATGGGTGACAGTGATGACGAGTACGATCGAAGGCGCAGGGACAAGTTCAG
AAGAGAGCGCAGCGACTACGACCGTTCCCGCGAGAGAGATGAAAGACGTCGAGGGGACGATTGGAATGACAGAGAGTGGGACCGTGGCCG
TGAGCGCCGTAGTCGGGGTGAATATCGGGACTATGACCGGAATCGGCGAGAGCGCTTCTCGCCACCTCGCCACGAACTCAGCCCGCCACA
GAAGCGCATGAGGAGAGACTGGGATGAGCACAGCTCTGACCCATACCACAGTGGCTATGAGATGCCCTATGCTGGGGGGGGTGGGGGCCC
AACTTATGGCCCCCCTCAGCCCTGGGGCCACCCTGACGTCCACATCATGCAGCACCATGTCCTGCCTATCCAGGCCAGGCTGGGCAGCAT
TGCAGAGATTGACCTGGGTGTGCCGCCGCCCGTGATGAAGACCTTCAAGGAGTTTCTCCTCTCCCTGGATGACTCGGTGGATGAGACGGA
GGCCGTCAAGCGCTATAATGACTACAAGCTGGATTTCCGGAGGCAACAGATGCAGGATTTCTTCCTGGCGCACAAAGATGAGGAGTGGTT
TCGGTCTAAGTACCACCCAGATGAGGTGGGGAAGCGTCGGCAGGAGGCCCGGGGGGCCCTGCAAAACCGACTGAGGGTCTTCCTGTCCCT
CATGGAGACTGGCTGGTTTGATAACCTTCTCCTGGACATAGACAAAGCTGATGCCATTGTCAAGATGCTGGATGCAGCCGTGATTAAGAT
GGAAGGAGGCACGGAGAATGATCTTCGCATCCTGGAGCAGGAGGAGGAGGAGGAGCAGGCAGGAAAGCCTGGGGAGCCCAGCAAGAAAGA
AGAAGGACGGGCTGGAGCAGGCCTAGGGGACGGGGAGCGCAAAACCAACGACAAGGATGAGAAGAAGGAAGACGGCAAGCAGGCTGAGAA
TGACAGTTCTAATGATGACAAAACAAAGAAGTCGGAGGGTGATGGGGACAAGGAAGAGAAGAAAGAAGACTCCGAGAAGGAAGCCAAAAA
GAGTAGCAAGAAGCGGAACCGGAAGCACAGTGGTGACGACAGCTTTGACGAGGGCAGCGTGTCAGAGTCTGAGTCGGAGTCAGAGAGCGG
CCAGGCTGAGGAGGAGAAGGAGGAGGCCGAAGCGCTCAAGGAGAAGGAGAAGCCCAAGGAAGAAGAATGGGAGAAGCCCAAGGACGCCGC
GGGGCTGGAGTGCAAGCCGCGGCCGCTGCATAAGACCTGCTCCCTCTTCATGCGCAACATCGCGCCCAACATCTCCCGGGCCGAGATCAT
CTCCCTTTGTAAAAGGTACCCAGGCTTTATGCGGGTGGCGCTCTCAGAGCCCCAGCCAGAGAGGAGGTTTTTCCGTCGTGGCTGGGTGAC
CTTCGACCGCAGTGTTAACATTAAAGAGATCTGTTGGAACCTGCAGAACATCCGTCTCCGGGAGTGTGAGCTGAGCCCTGGTGTGAACAG
GGACCTGACCCGGCGCGTTCGCAACATCAACGGCATCACCCAGCACAAGCAGATTGTGCGCAACGACATCAAGCTGGCGGCCAAGCTGAT
CCACACGCTGGATGACAGGACACAGCTTTGGGCCTCAGAACCAGGGACGCCTCCCCTGCCCACGAGGGAACCCGGCAGAGATCAACGTGG
AGCGGGATGAGAAGTTGATTAAGCCTCCAAGGAGTAAGACCCCTGGACCACCAGCCCCAGCAAGAGCACAAGAGGAAGAGAGAGACCCTC
ACTGCTGGGGAGTCCCTGCCACACTCAGTCCCCCACCACACTGAATCTCCCCTCCTCACAGTTGCCATGTAGACCCCTTGAAGAGGGGAG

>86572_86572_3_SRRT-GAPDH_SRRT_chr7_100484540_ENST00000388793_GAPDH_chr12_6647322_ENST00000229239_length(amino acids)=559AA_BP=
MGDSDDEYDRRRRDKFRRERSDYDRSRERDERRRGDDWNDREWDRGRERRSRGEYRDYDRNRRERFSPPRHELSPPQKRMRRDWDEHSSD
PYHSGYEMPYAGGGGGPTYGPPQPWGHPDVHIMQHHVLPIQARLGSIAEIDLGVPPPVMKTFKEFLLSLDDSVDETEAVKRYNDYKLDFR
RQQMQDFFLAHKDEEWFRSKYHPDEVGKRRQEARGALQNRLRVFLSLMETGWFDNLLLDIDKADAIVKMLDAAVIKMEGGTENDLRILEQ
EEEEEQAGKPGEPSKKEEGRAGAGLGDGERKTNDKDEKKEDGKQAENDSSNDDKTKKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDD
SFDEGSVSESESESESGQAEEEKEEAEALKEKEKPKEEEWEKPKDAAGLECKPRPLHKTCSLFMRNIAPNISRAEIISLCKRYPGFMRVA
LSEPQPERRFFRRGWVTFDRSVNIKEICWNLQNIRLRECELSPGVNRDLTRRVRNINGITQHKQIVRNDIKLAAKLIHTLDDRTQLWASE

--------------------------------------------------------------
>86572_86572_4_SRRT-GAPDH_SRRT_chr7_100484540_ENST00000388793_GAPDH_chr12_6647322_ENST00000396861_length(transcript)=2116nt_BP=1913nt
GGGTGACGCAGGCGCAGCGCGGGCTGCGCGCGCTACTGCCCATCCCCGGTTGTCCCACTTTTGTTCGCCTCTCTTCGGCCCTCTACTCAA
GAGCTCCGTCTCCGTCTCGCCCTCCTCGAAGTCCTCGTCGCGCGCCCGCGACCCAGGTCGCCCTGAAATCTAGCCCGTCCGAGCGCGAGT
CCAACGCCGCGGCCGCACCAAGGCCCCCTCAGACCGTGCCATGGGTGACAGTGATGACGAGTACGATCGAAGGCGCAGGGACAAGTTCAG
AAGAGAGCGCAGCGACTACGACCGTTCCCGCGAGAGAGATGAAAGACGTCGAGGGGACGATTGGAATGACAGAGAGTGGGACCGTGGCCG
TGAGCGCCGTAGTCGGGGTGAATATCGGGACTATGACCGGAATCGGCGAGAGCGCTTCTCGCCACCTCGCCACGAACTCAGCCCGCCACA
GAAGCGCATGAGGAGAGACTGGGATGAGCACAGCTCTGACCCATACCACAGTGGCTATGAGATGCCCTATGCTGGGGGGGGTGGGGGCCC
AACTTATGGCCCCCCTCAGCCCTGGGGCCACCCTGACGTCCACATCATGCAGCACCATGTCCTGCCTATCCAGGCCAGGCTGGGCAGCAT
TGCAGAGATTGACCTGGGTGTGCCGCCGCCCGTGATGAAGACCTTCAAGGAGTTTCTCCTCTCCCTGGATGACTCGGTGGATGAGACGGA
GGCCGTCAAGCGCTATAATGACTACAAGCTGGATTTCCGGAGGCAACAGATGCAGGATTTCTTCCTGGCGCACAAAGATGAGGAGTGGTT
TCGGTCTAAGTACCACCCAGATGAGGTGGGGAAGCGTCGGCAGGAGGCCCGGGGGGCCCTGCAAAACCGACTGAGGGTCTTCCTGTCCCT
CATGGAGACTGGCTGGTTTGATAACCTTCTCCTGGACATAGACAAAGCTGATGCCATTGTCAAGATGCTGGATGCAGCCGTGATTAAGAT
GGAAGGAGGCACGGAGAATGATCTTCGCATCCTGGAGCAGGAGGAGGAGGAGGAGCAGGCAGGAAAGCCTGGGGAGCCCAGCAAGAAAGA
AGAAGGACGGGCTGGAGCAGGCCTAGGGGACGGGGAGCGCAAAACCAACGACAAGGATGAGAAGAAGGAAGACGGCAAGCAGGCTGAGAA
TGACAGTTCTAATGATGACAAAACAAAGAAGTCGGAGGGTGATGGGGACAAGGAAGAGAAGAAAGAAGACTCCGAGAAGGAAGCCAAAAA
GAGTAGCAAGAAGCGGAACCGGAAGCACAGTGGTGACGACAGCTTTGACGAGGGCAGCGTGTCAGAGTCTGAGTCGGAGTCAGAGAGCGG
CCAGGCTGAGGAGGAGAAGGAGGAGGCCGAAGCGCTCAAGGAGAAGGAGAAGCCCAAGGAAGAAGAATGGGAGAAGCCCAAGGACGCCGC
GGGGCTGGAGTGCAAGCCGCGGCCGCTGCATAAGACCTGCTCCCTCTTCATGCGCAACATCGCGCCCAACATCTCCCGGGCCGAGATCAT
CTCCCTTTGTAAAAGGTACCCAGGCTTTATGCGGGTGGCGCTCTCAGAGCCCCAGCCAGAGAGGAGGTTTTTCCGTCGTGGCTGGGTGAC
CTTCGACCGCAGTGTTAACATTAAAGAGATCTGTTGGAACCTGCAGAACATCCGTCTCCGGGAGTGTGAGCTGAGCCCTGGTGTGAACAG
GGACCTGACCCGGCGCGTTCGCAACATCAACGGCATCACCCAGCACAAGCAGATTGTGCGCAACGACATCAAGCTGGCGGCCAAGCTGAT
CCACACGCTGGATGACAGGACACAGCTTTGGGCCTCAGAACCAGGGACGCCTCCCCTGCCCACGAGGGAACCCGGCAGAGATCAACGTGG
AGCGGGATGAGAAGTTGATTAAGCCTCCAAGGAGTAAGACCCCTGGACCACCAGCCCCAGCAAGAGCACAAGAGGAAGAGAGAGACCCTC
ACTGCTGGGGAGTCCCTGCCACACTCAGTCCCCCACCACACTGAATCTCCCCTCCTCACAGTTGCCATGTAGACCCCTTGAAGAGGGGAG

>86572_86572_4_SRRT-GAPDH_SRRT_chr7_100484540_ENST00000388793_GAPDH_chr12_6647322_ENST00000396861_length(amino acids)=559AA_BP=
MGDSDDEYDRRRRDKFRRERSDYDRSRERDERRRGDDWNDREWDRGRERRSRGEYRDYDRNRRERFSPPRHELSPPQKRMRRDWDEHSSD
PYHSGYEMPYAGGGGGPTYGPPQPWGHPDVHIMQHHVLPIQARLGSIAEIDLGVPPPVMKTFKEFLLSLDDSVDETEAVKRYNDYKLDFR
RQQMQDFFLAHKDEEWFRSKYHPDEVGKRRQEARGALQNRLRVFLSLMETGWFDNLLLDIDKADAIVKMLDAAVIKMEGGTENDLRILEQ
EEEEEQAGKPGEPSKKEEGRAGAGLGDGERKTNDKDEKKEDGKQAENDSSNDDKTKKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDD
SFDEGSVSESESESESGQAEEEKEEAEALKEKEKPKEEEWEKPKDAAGLECKPRPLHKTCSLFMRNIAPNISRAEIISLCKRYPGFMRVA
LSEPQPERRFFRRGWVTFDRSVNIKEICWNLQNIRLRECELSPGVNRDLTRRVRNINGITQHKQIVRNDIKLAAKLIHTLDDRTQLWASE

--------------------------------------------------------------
>86572_86572_5_SRRT-GAPDH_SRRT_chr7_100484540_ENST00000432932_GAPDH_chr12_6647322_ENST00000229239_length(transcript)=2069nt_BP=1854nt
TTTGTTCGCCTCTCTTCGGCCCTCTACTCAAGAGCTCCGTCTCCGTCTCGCCCTCCTCGAAGTCCTCGTCGCGCGCCCGCGACCCAGGTC
GCCCTGAAATCTAGCCCGTCCGAGCGCGAGTCCAACGCCGCGGCCGCACCAAGGCCCCCTCAGACCGTGCCATGGGTGACAGTGATGACG
AGTACGATCGAAGGCGCAGGGACAAGTTCAGAAGAGAGCGCAGCGACTACGACCGTTCCCGCGAGAGAGATGAAAGACGTCGAGGGGACG
ATTGGAATGACAGAGAGTGGGACCGTGGCCGTGAGCGCCGTAGTCGGGGTGAATATCGGGACTATGACCGGAATCGGCGAGAGCGCTTCT
CGCCACCTCGCCACGAACTCAGCCCGCCACAGAAGCGCATGAGGAGAGACTGGGATGAGCACAGCTCTGACCCATACCACAGTGGCTATG
AGATGCCCTATGCTGGGGGGGGTGGGGGCCCAACTTATGGCCCCCCTCAGCCCTGGGGCCACCCTGACGTCCACATCATGCAGCACCATG
TCCTGCCTATCCAGGCCAGGCTGGGCAGCATTGCAGAGATTGACCTGGGTGTGCCGCCGCCCGTGATGAAGACCTTCAAGGAGTTTCTCC
TCTCCCTGGATGACTCGGTGGATGAGACGGAGGCCGTCAAGCGCTATAATGACTACAAGCTGGATTTCCGGAGGCAACAGATGCAGGATT
TCTTCCTGGCGCACAAAGATGAGGAGTGGTTTCGGTCTAAGTACCACCCAGATGAGGTGGGGAAGCGTCGGCAGGAGGCCCGGGGGGCCC
TGCAAAACCGACTGAGGGTCTTCCTGTCCCTCATGGAGACTGGCTGGTTTGATAACCTTCTCCTGGACATAGACAAAGCTGATGCCATTG
TCAAGATGCTGGATGCAGCCGTGATTAAGATGGAAGGAGGCACGGAGAATGATCTTCGCATCCTGGAGCAGGAGGAGGAGGAGGAGCAGG
CAGGAAAGCCTGGGGAGCCCAGCAAGAAAGAAGAAGGACGGGCTGGAGCAGGCCTAGGGGACGGGGAGCGCAAAACCAACGACAAGGATG
AGAAGAAGGAAGACGGCAAGCAGGCTGAGAATGACAGTTCTAATGATGACAAAACAAAGAAGTCGGAGGGTGATGGGGACAAGGAAGAGA
AGAAAGAAGACTCCGAGAAGGAAGCCAAAAAGAGTAGCAAGAAGCGGAACCGGAAGCACAGTGGTGACGACAGCTTTGACGAGGGCAGCG
TGTCAGAGTCTGAGTCGGAGTCAGAGAGCGGCCAGGCTGAGGAGGAGAAGGAGGAGGCCGAAGCGCTCAAGGAGAAGGAGAAGCCCAAGG
AAGAAGAATGGGAGAAGCCCAAGGACGCCGCGGGGCTGGAGTGCAAGCCGCGGCCGCTGCATAAGACCTGCTCCCTCTTCATGCGCAACA
TCGCGCCCAACATCTCCCGGGCCGAGATCATCTCCCTTTGTAAAAGGTACCCAGGCTTTATGCGGGTGGCGCTCTCAGAGCCCCAGCCAG
AGAGGAGGTTTTTCCGTCGTGGCTGGGTGACCTTCGACCGCAGTGTTAACATTAAAGAGATCTGTTGGAACCTGCAGAACATCCGTCTCC
GGGAGTGTGAGCTGAGCCCTGGTGTGAACAGGGACCTGACCCGGCGCGTTCGCAACATCAACGGCATCACCCAGCACAAGCAGATTGTGC
GCAACGACATCAAGCTGGCGGCCAAGCTGATCCACACGCTGGATGACAGGACACAGCTTTGGGCCTCAGAACCAGGGACGCCTCCCCTGC
CCACGAGGGAACCCGGCAGAGATCAACGTGGAGCGGGATGAGAAGTTGATTAAGCCTCCAAGGAGTAAGACCCCTGGACCACCAGCCCCA
GCAAGAGCACAAGAGGAAGAGAGAGACCCTCACTGCTGGGGAGTCCCTGCCACACTCAGTCCCCCACCACACTGAATCTCCCCTCCTCAC

>86572_86572_5_SRRT-GAPDH_SRRT_chr7_100484540_ENST00000432932_GAPDH_chr12_6647322_ENST00000229239_length(amino acids)=559AA_BP=
MGDSDDEYDRRRRDKFRRERSDYDRSRERDERRRGDDWNDREWDRGRERRSRGEYRDYDRNRRERFSPPRHELSPPQKRMRRDWDEHSSD
PYHSGYEMPYAGGGGGPTYGPPQPWGHPDVHIMQHHVLPIQARLGSIAEIDLGVPPPVMKTFKEFLLSLDDSVDETEAVKRYNDYKLDFR
RQQMQDFFLAHKDEEWFRSKYHPDEVGKRRQEARGALQNRLRVFLSLMETGWFDNLLLDIDKADAIVKMLDAAVIKMEGGTENDLRILEQ
EEEEEQAGKPGEPSKKEEGRAGAGLGDGERKTNDKDEKKEDGKQAENDSSNDDKTKKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDD
SFDEGSVSESESESESGQAEEEKEEAEALKEKEKPKEEEWEKPKDAAGLECKPRPLHKTCSLFMRNIAPNISRAEIISLCKRYPGFMRVA
LSEPQPERRFFRRGWVTFDRSVNIKEICWNLQNIRLRECELSPGVNRDLTRRVRNINGITQHKQIVRNDIKLAAKLIHTLDDRTQLWASE

--------------------------------------------------------------
>86572_86572_6_SRRT-GAPDH_SRRT_chr7_100484540_ENST00000432932_GAPDH_chr12_6647322_ENST00000396861_length(transcript)=2057nt_BP=1854nt
TTTGTTCGCCTCTCTTCGGCCCTCTACTCAAGAGCTCCGTCTCCGTCTCGCCCTCCTCGAAGTCCTCGTCGCGCGCCCGCGACCCAGGTC
GCCCTGAAATCTAGCCCGTCCGAGCGCGAGTCCAACGCCGCGGCCGCACCAAGGCCCCCTCAGACCGTGCCATGGGTGACAGTGATGACG
AGTACGATCGAAGGCGCAGGGACAAGTTCAGAAGAGAGCGCAGCGACTACGACCGTTCCCGCGAGAGAGATGAAAGACGTCGAGGGGACG
ATTGGAATGACAGAGAGTGGGACCGTGGCCGTGAGCGCCGTAGTCGGGGTGAATATCGGGACTATGACCGGAATCGGCGAGAGCGCTTCT
CGCCACCTCGCCACGAACTCAGCCCGCCACAGAAGCGCATGAGGAGAGACTGGGATGAGCACAGCTCTGACCCATACCACAGTGGCTATG
AGATGCCCTATGCTGGGGGGGGTGGGGGCCCAACTTATGGCCCCCCTCAGCCCTGGGGCCACCCTGACGTCCACATCATGCAGCACCATG
TCCTGCCTATCCAGGCCAGGCTGGGCAGCATTGCAGAGATTGACCTGGGTGTGCCGCCGCCCGTGATGAAGACCTTCAAGGAGTTTCTCC
TCTCCCTGGATGACTCGGTGGATGAGACGGAGGCCGTCAAGCGCTATAATGACTACAAGCTGGATTTCCGGAGGCAACAGATGCAGGATT
TCTTCCTGGCGCACAAAGATGAGGAGTGGTTTCGGTCTAAGTACCACCCAGATGAGGTGGGGAAGCGTCGGCAGGAGGCCCGGGGGGCCC
TGCAAAACCGACTGAGGGTCTTCCTGTCCCTCATGGAGACTGGCTGGTTTGATAACCTTCTCCTGGACATAGACAAAGCTGATGCCATTG
TCAAGATGCTGGATGCAGCCGTGATTAAGATGGAAGGAGGCACGGAGAATGATCTTCGCATCCTGGAGCAGGAGGAGGAGGAGGAGCAGG
CAGGAAAGCCTGGGGAGCCCAGCAAGAAAGAAGAAGGACGGGCTGGAGCAGGCCTAGGGGACGGGGAGCGCAAAACCAACGACAAGGATG
AGAAGAAGGAAGACGGCAAGCAGGCTGAGAATGACAGTTCTAATGATGACAAAACAAAGAAGTCGGAGGGTGATGGGGACAAGGAAGAGA
AGAAAGAAGACTCCGAGAAGGAAGCCAAAAAGAGTAGCAAGAAGCGGAACCGGAAGCACAGTGGTGACGACAGCTTTGACGAGGGCAGCG
TGTCAGAGTCTGAGTCGGAGTCAGAGAGCGGCCAGGCTGAGGAGGAGAAGGAGGAGGCCGAAGCGCTCAAGGAGAAGGAGAAGCCCAAGG
AAGAAGAATGGGAGAAGCCCAAGGACGCCGCGGGGCTGGAGTGCAAGCCGCGGCCGCTGCATAAGACCTGCTCCCTCTTCATGCGCAACA
TCGCGCCCAACATCTCCCGGGCCGAGATCATCTCCCTTTGTAAAAGGTACCCAGGCTTTATGCGGGTGGCGCTCTCAGAGCCCCAGCCAG
AGAGGAGGTTTTTCCGTCGTGGCTGGGTGACCTTCGACCGCAGTGTTAACATTAAAGAGATCTGTTGGAACCTGCAGAACATCCGTCTCC
GGGAGTGTGAGCTGAGCCCTGGTGTGAACAGGGACCTGACCCGGCGCGTTCGCAACATCAACGGCATCACCCAGCACAAGCAGATTGTGC
GCAACGACATCAAGCTGGCGGCCAAGCTGATCCACACGCTGGATGACAGGACACAGCTTTGGGCCTCAGAACCAGGGACGCCTCCCCTGC
CCACGAGGGAACCCGGCAGAGATCAACGTGGAGCGGGATGAGAAGTTGATTAAGCCTCCAAGGAGTAAGACCCCTGGACCACCAGCCCCA
GCAAGAGCACAAGAGGAAGAGAGAGACCCTCACTGCTGGGGAGTCCCTGCCACACTCAGTCCCCCACCACACTGAATCTCCCCTCCTCAC

>86572_86572_6_SRRT-GAPDH_SRRT_chr7_100484540_ENST00000432932_GAPDH_chr12_6647322_ENST00000396861_length(amino acids)=559AA_BP=
MGDSDDEYDRRRRDKFRRERSDYDRSRERDERRRGDDWNDREWDRGRERRSRGEYRDYDRNRRERFSPPRHELSPPQKRMRRDWDEHSSD
PYHSGYEMPYAGGGGGPTYGPPQPWGHPDVHIMQHHVLPIQARLGSIAEIDLGVPPPVMKTFKEFLLSLDDSVDETEAVKRYNDYKLDFR
RQQMQDFFLAHKDEEWFRSKYHPDEVGKRRQEARGALQNRLRVFLSLMETGWFDNLLLDIDKADAIVKMLDAAVIKMEGGTENDLRILEQ
EEEEEQAGKPGEPSKKEEGRAGAGLGDGERKTNDKDEKKEDGKQAENDSSNDDKTKKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDD
SFDEGSVSESESESESGQAEEEKEEAEALKEKEKPKEEEWEKPKDAAGLECKPRPLHKTCSLFMRNIAPNISRAEIISLCKRYPGFMRVA
LSEPQPERRFFRRGWVTFDRSVNIKEICWNLQNIRLRECELSPGVNRDLTRRVRNINGITQHKQIVRNDIKLAAKLIHTLDDRTQLWASE

--------------------------------------------------------------
>86572_86572_7_SRRT-GAPDH_SRRT_chr7_100484540_ENST00000457580_GAPDH_chr12_6647322_ENST00000229239_length(transcript)=2131nt_BP=1916nt
GGGTGACGCAGGCGCAGCGCGGGCTGCGCGCGCTACTGCCCATCCCCGGTTGTCCCACTTTTGTTCGCCTCTCTTCGGCCCTCTACTCAA
GAGCTCCGTCTCCGTCTCGCCCTCCTCGAAGTCCTCGTCGCGCGCCCGCGACCCAGGTCGCCCTGAAATCTAGCCCGTCCGAGCGCGAGT
CCAACGCCGCGGCCGCACCAAGGCCCCCTCAGACCGTGCCATGGGTGACAGTGATGACGAGTACGATCGAAGGCGCAGGGACAAGTTCAG
AAGAGAGCGCAGCGACTACGACCGTTCCCGCGAGAGAGATGAAAGACGTCGAGGGGACGATTGGAATGACAGAGAGTGGGACCGTGGCCG
TGAGCGCCGTAGTCGGGGTGAATATCGGGACTATGACCGGAATCGGCGAGAGCGCTTCTCGCCACCTCGCCACGAACTCAGCCCGCCACA
GAAGCGCATGAGGAGAGACTGGGATGAGCACAGCTCTGACCCATACCACAGTGGCTATGAGATGCCCTATGCTGGGGGGGGTGGGGGCCC
AACTTATGGCCCCCCTCAGCCCTGGGGCCACCCTGACGTCCACATCATGCAGCACCATGTCCTGCCTATCCAGGCCAGGCTGGGCAGCAT
TGCAGAGATTGACCTGGGTGTGCCGCCGCCCGTGATGAAGACCTTCAAGGAGTTTCTCCTCTCCCTGGATGACTCGGTGGATGAGACGGA
GGCCGTCAAGCGCTATAATGACTACAAGCTGGATTTCCGGAGGCAACAGATGCAGGATTTCTTCCTGGCGCACAAAGATGAGGAGTGGTT
TCGGTCTAAGTACCACCCAGATGAGGTGGGGAAGCGTCGGCAGGAGGCCCGGGGGGCCCTGCAAAACCGACTGAGGGTCTTCCTGTCCCT
CATGGAGACTGGCTGGTTTGATAACCTTCTCCTGGACATAGACAAAGCTGATGCCATTGTCAAGATGCTGGATGCAGCCGTGATTAAGAT
GGAAGGAGGCACGGAGAATGATCTTCGCATCCTGGAGCAGGAGGAGGAGGAGGAGCAGGCAGGAAAGCCTGGGGAGCCCAGCAAGAAAGA
AGAAGGACGGGCTGGAGCAGGCCTAGGGGACGGGGAGCGCAAAACCAACGACAAGGATGAGAAGAAGGAAGACGGCAAGCAGGCTGAGAA
TGACAGTTCTAATGATGACAAAACAAAGAAGTCGGAGGGTGATGGGGACAAGGAAGAGAAGAAAGAAGACTCCGAGAAGGAAGCCAAAAA
GAGTAGCAAGAAGCGGAACCGGAAGCACAGTGGTGACGACAGCTTTGACGAGGGCAGCGTGTCAGAGTCTGAGTCGGAGTCAGAGAGCGG
CCAGGCTGAGGAGGAGAAGGAGGAGGCCGAAGAAGCGCTCAAGGAGAAGGAGAAGCCCAAGGAAGAAGAATGGGAGAAGCCCAAGGACGC
CGCGGGGCTGGAGTGCAAGCCGCGGCCGCTGCATAAGACCTGCTCCCTCTTCATGCGCAACATCGCGCCCAACATCTCCCGGGCCGAGAT
CATCTCCCTTTGTAAAAGGTACCCAGGCTTTATGCGGGTGGCGCTCTCAGAGCCCCAGCCAGAGAGGAGGTTTTTCCGTCGTGGCTGGGT
GACCTTCGACCGCAGTGTTAACATTAAAGAGATCTGTTGGAACCTGCAGAACATCCGTCTCCGGGAGTGTGAGCTGAGCCCTGGTGTGAA
CAGGGACCTGACCCGGCGCGTTCGCAACATCAACGGCATCACCCAGCACAAGCAGATTGTGCGCAACGACATCAAGCTGGCGGCCAAGCT
GATCCACACGCTGGATGACAGGACACAGCTTTGGGCCTCAGAACCAGGGACGCCTCCCCTGCCCACGAGGGAACCCGGCAGAGATCAACG
TGGAGCGGGATGAGAAGTTGATTAAGCCTCCAAGGAGTAAGACCCCTGGACCACCAGCCCCAGCAAGAGCACAAGAGGAAGAGAGAGACC
CTCACTGCTGGGGAGTCCCTGCCACACTCAGTCCCCCACCACACTGAATCTCCCCTCCTCACAGTTGCCATGTAGACCCCTTGAAGAGGG

>86572_86572_7_SRRT-GAPDH_SRRT_chr7_100484540_ENST00000457580_GAPDH_chr12_6647322_ENST00000229239_length(amino acids)=560AA_BP=
MGDSDDEYDRRRRDKFRRERSDYDRSRERDERRRGDDWNDREWDRGRERRSRGEYRDYDRNRRERFSPPRHELSPPQKRMRRDWDEHSSD
PYHSGYEMPYAGGGGGPTYGPPQPWGHPDVHIMQHHVLPIQARLGSIAEIDLGVPPPVMKTFKEFLLSLDDSVDETEAVKRYNDYKLDFR
RQQMQDFFLAHKDEEWFRSKYHPDEVGKRRQEARGALQNRLRVFLSLMETGWFDNLLLDIDKADAIVKMLDAAVIKMEGGTENDLRILEQ
EEEEEQAGKPGEPSKKEEGRAGAGLGDGERKTNDKDEKKEDGKQAENDSSNDDKTKKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDD
SFDEGSVSESESESESGQAEEEKEEAEEALKEKEKPKEEEWEKPKDAAGLECKPRPLHKTCSLFMRNIAPNISRAEIISLCKRYPGFMRV
ALSEPQPERRFFRRGWVTFDRSVNIKEICWNLQNIRLRECELSPGVNRDLTRRVRNINGITQHKQIVRNDIKLAAKLIHTLDDRTQLWAS

--------------------------------------------------------------
>86572_86572_8_SRRT-GAPDH_SRRT_chr7_100484540_ENST00000457580_GAPDH_chr12_6647322_ENST00000396861_length(transcript)=2119nt_BP=1916nt
GGGTGACGCAGGCGCAGCGCGGGCTGCGCGCGCTACTGCCCATCCCCGGTTGTCCCACTTTTGTTCGCCTCTCTTCGGCCCTCTACTCAA
GAGCTCCGTCTCCGTCTCGCCCTCCTCGAAGTCCTCGTCGCGCGCCCGCGACCCAGGTCGCCCTGAAATCTAGCCCGTCCGAGCGCGAGT
CCAACGCCGCGGCCGCACCAAGGCCCCCTCAGACCGTGCCATGGGTGACAGTGATGACGAGTACGATCGAAGGCGCAGGGACAAGTTCAG
AAGAGAGCGCAGCGACTACGACCGTTCCCGCGAGAGAGATGAAAGACGTCGAGGGGACGATTGGAATGACAGAGAGTGGGACCGTGGCCG
TGAGCGCCGTAGTCGGGGTGAATATCGGGACTATGACCGGAATCGGCGAGAGCGCTTCTCGCCACCTCGCCACGAACTCAGCCCGCCACA
GAAGCGCATGAGGAGAGACTGGGATGAGCACAGCTCTGACCCATACCACAGTGGCTATGAGATGCCCTATGCTGGGGGGGGTGGGGGCCC
AACTTATGGCCCCCCTCAGCCCTGGGGCCACCCTGACGTCCACATCATGCAGCACCATGTCCTGCCTATCCAGGCCAGGCTGGGCAGCAT
TGCAGAGATTGACCTGGGTGTGCCGCCGCCCGTGATGAAGACCTTCAAGGAGTTTCTCCTCTCCCTGGATGACTCGGTGGATGAGACGGA
GGCCGTCAAGCGCTATAATGACTACAAGCTGGATTTCCGGAGGCAACAGATGCAGGATTTCTTCCTGGCGCACAAAGATGAGGAGTGGTT
TCGGTCTAAGTACCACCCAGATGAGGTGGGGAAGCGTCGGCAGGAGGCCCGGGGGGCCCTGCAAAACCGACTGAGGGTCTTCCTGTCCCT
CATGGAGACTGGCTGGTTTGATAACCTTCTCCTGGACATAGACAAAGCTGATGCCATTGTCAAGATGCTGGATGCAGCCGTGATTAAGAT
GGAAGGAGGCACGGAGAATGATCTTCGCATCCTGGAGCAGGAGGAGGAGGAGGAGCAGGCAGGAAAGCCTGGGGAGCCCAGCAAGAAAGA
AGAAGGACGGGCTGGAGCAGGCCTAGGGGACGGGGAGCGCAAAACCAACGACAAGGATGAGAAGAAGGAAGACGGCAAGCAGGCTGAGAA
TGACAGTTCTAATGATGACAAAACAAAGAAGTCGGAGGGTGATGGGGACAAGGAAGAGAAGAAAGAAGACTCCGAGAAGGAAGCCAAAAA
GAGTAGCAAGAAGCGGAACCGGAAGCACAGTGGTGACGACAGCTTTGACGAGGGCAGCGTGTCAGAGTCTGAGTCGGAGTCAGAGAGCGG
CCAGGCTGAGGAGGAGAAGGAGGAGGCCGAAGAAGCGCTCAAGGAGAAGGAGAAGCCCAAGGAAGAAGAATGGGAGAAGCCCAAGGACGC
CGCGGGGCTGGAGTGCAAGCCGCGGCCGCTGCATAAGACCTGCTCCCTCTTCATGCGCAACATCGCGCCCAACATCTCCCGGGCCGAGAT
CATCTCCCTTTGTAAAAGGTACCCAGGCTTTATGCGGGTGGCGCTCTCAGAGCCCCAGCCAGAGAGGAGGTTTTTCCGTCGTGGCTGGGT
GACCTTCGACCGCAGTGTTAACATTAAAGAGATCTGTTGGAACCTGCAGAACATCCGTCTCCGGGAGTGTGAGCTGAGCCCTGGTGTGAA
CAGGGACCTGACCCGGCGCGTTCGCAACATCAACGGCATCACCCAGCACAAGCAGATTGTGCGCAACGACATCAAGCTGGCGGCCAAGCT
GATCCACACGCTGGATGACAGGACACAGCTTTGGGCCTCAGAACCAGGGACGCCTCCCCTGCCCACGAGGGAACCCGGCAGAGATCAACG
TGGAGCGGGATGAGAAGTTGATTAAGCCTCCAAGGAGTAAGACCCCTGGACCACCAGCCCCAGCAAGAGCACAAGAGGAAGAGAGAGACC
CTCACTGCTGGGGAGTCCCTGCCACACTCAGTCCCCCACCACACTGAATCTCCCCTCCTCACAGTTGCCATGTAGACCCCTTGAAGAGGG

>86572_86572_8_SRRT-GAPDH_SRRT_chr7_100484540_ENST00000457580_GAPDH_chr12_6647322_ENST00000396861_length(amino acids)=560AA_BP=
MGDSDDEYDRRRRDKFRRERSDYDRSRERDERRRGDDWNDREWDRGRERRSRGEYRDYDRNRRERFSPPRHELSPPQKRMRRDWDEHSSD
PYHSGYEMPYAGGGGGPTYGPPQPWGHPDVHIMQHHVLPIQARLGSIAEIDLGVPPPVMKTFKEFLLSLDDSVDETEAVKRYNDYKLDFR
RQQMQDFFLAHKDEEWFRSKYHPDEVGKRRQEARGALQNRLRVFLSLMETGWFDNLLLDIDKADAIVKMLDAAVIKMEGGTENDLRILEQ
EEEEEQAGKPGEPSKKEEGRAGAGLGDGERKTNDKDEKKEDGKQAENDSSNDDKTKKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDD
SFDEGSVSESESESESGQAEEEKEEAEEALKEKEKPKEEEWEKPKDAAGLECKPRPLHKTCSLFMRNIAPNISRAEIISLCKRYPGFMRV
ALSEPQPERRFFRRGWVTFDRSVNIKEICWNLQNIRLRECELSPGVNRDLTRRVRNINGITQHKQIVRNDIKLAAKLIHTLDDRTQLWAS

--------------------------------------------------------------

Top

Fusion Gene PPI Analysis for SRRT-GAPDH


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with
TgeneGAPDHchr7:100484540chr12:6647322ENST00000229239092_1480336.0WARS1
TgeneGAPDHchr7:100484540chr12:6647322ENST00000396858082_1480294.0WARS1
TgeneGAPDHchr7:100484540chr12:6647322ENST00000396859082_1480336.0WARS1
TgeneGAPDHchr7:100484540chr12:6647322ENST00000396861092_1480336.0WARS1


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


Top

Related Drugs for SRRT-GAPDH


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

Top

Related Diseases for SRRT-GAPDH


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource