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	Fusion Gene Summary
	Fusion Gene ORF analysis
	Fusion Genomic Features
	Fusion Protein Features
	Fusion Gene Sequence
	Fusion Gene PPI analysis
	Related Drugs
	Related Diseases

Fusion gene:B3GALNT2-LYST (FusionGDB2 ID:8661)

Fusion Gene Summary for B3GALNT2-LYST

Fusion gene summary

Fusion gene information	Fusion gene name: B3GALNT2-LYST
	Fusion gene ID: 8661
		Hgene	Tgene
	Gene symbol	B3GALNT2	LYST
	Gene ID	148789	1130
	Gene name	beta-1,3-N-acetylgalactosaminyltransferase 2	lysosomal trafficking regulator
	Synonyms	B3GalNAc-T2\|MDDGA11	CHS\|CHS1
	Cytomap	1q42.3	1q42.3
	Type of gene	protein-coding	protein-coding
	Description	UDP-GalNAc:beta-1,3-N-acetylgalactosaminyltransferase 2UDP-GalNAc:betaGlcNAc beta-1,3-galactosaminyltransferase, polypeptide 2beta-1,3-GalNAc-T2	lysosomal-trafficking regulatorChediak-Higashi syndrome 1beige homolog
	Modification date	20200313	20200313
	UniProtAcc	.	Q99698
	Ensembl transtripts involved in fusion gene	ENST00000313984, ENST00000366600, ENST00000494378,	ENST00000473037, ENST00000536965, ENST00000389793, ENST00000389794,
Fusion gene scores	* DoF score	7 X 8 X 7=392	8 X 8 X 5=320
	# samples	8	8
	** MAII score	log2(8/392*10)=-2.29278174922785 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0	log2(8/320*10)=-2 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0
Context	PubMed: B3GALNT2 [Title/Abstract] AND LYST [Title/Abstract] AND fusion [Title/Abstract]
Most frequent breakpoint	B3GALNT2(235647638)-LYST(235850347), # samples:1
Anticipated loss of major functional domain due to fusion event.

* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Partner	Gene	GO ID	GO term	PubMed ID
Hgene	B3GALNT2	GO:0006493	protein O-linked glycosylation	23929950

Fusion gene breakpoints across B3GALNT2 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion gene breakpoints across LYST (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

Source	Disease	Sample	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
ChimerDB4	BLCA	TCGA-G2-AA3B-01A	B3GALNT2	chr1	235647638	-	LYST	chr1	235850347	-

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Fusion Gene ORF analysis for B3GALNT2-LYST

Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

ORF	Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
5CDS-5UTR	ENST00000313984	ENST00000473037	B3GALNT2	chr1	235647638	-	LYST	chr1	235850347	-
5CDS-5UTR	ENST00000366600	ENST00000473037	B3GALNT2	chr1	235647638	-	LYST	chr1	235850347	-
5CDS-intron	ENST00000313984	ENST00000536965	B3GALNT2	chr1	235647638	-	LYST	chr1	235850347	-
5CDS-intron	ENST00000366600	ENST00000536965	B3GALNT2	chr1	235647638	-	LYST	chr1	235850347	-
5UTR-3CDS	ENST00000494378	ENST00000389793	B3GALNT2	chr1	235647638	-	LYST	chr1	235850347	-
5UTR-3CDS	ENST00000494378	ENST00000389794	B3GALNT2	chr1	235647638	-	LYST	chr1	235850347	-
5UTR-5UTR	ENST00000494378	ENST00000473037	B3GALNT2	chr1	235647638	-	LYST	chr1	235850347	-
5UTR-intron	ENST00000494378	ENST00000536965	B3GALNT2	chr1	235647638	-	LYST	chr1	235850347	-
In-frame	ENST00000313984	ENST00000389793	B3GALNT2	chr1	235647638	-	LYST	chr1	235850347	-
In-frame	ENST00000313984	ENST00000389794	B3GALNT2	chr1	235647638	-	LYST	chr1	235850347	-
In-frame	ENST00000366600	ENST00000389793	B3GALNT2	chr1	235647638	-	LYST	chr1	235850347	-
In-frame	ENST00000366600	ENST00000389794	B3GALNT2	chr1	235647638	-	LYST	chr1	235850347	-

ORFfinder result based on the fusion transcript sequence of in-frame fusion genes.

Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	Seq length (transcript)	BP loci (transcript)	Predicted start (transcript)	Predicted stop (transcript)	Seq length (amino acids)
ENST00000366600	B3GALNT2	chr1	235647638	-	ENST00000389794	LYST	chr1	235850347	-	3388	784	49	1488	479
ENST00000366600	B3GALNT2	chr1	235647638	-	ENST00000389793	LYST	chr1	235850347	-	3379	784	49	1488	479
ENST00000313984	B3GALNT2	chr1	235647638	-	ENST00000389794	LYST	chr1	235850347	-	3452	848	170	1552	460
ENST00000313984	B3GALNT2	chr1	235647638	-	ENST00000389793	LYST	chr1	235850347	-	3443	848	170	1552	460

DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.

Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	No-coding score	Coding score
ENST00000366600	ENST00000389794	B3GALNT2	chr1	235647638	-	LYST	chr1	235850347	-	0.000388398	0.9996117
ENST00000366600	ENST00000389793	B3GALNT2	chr1	235647638	-	LYST	chr1	235850347	-	0.000392793	0.99960726
ENST00000313984	ENST00000389794	B3GALNT2	chr1	235647638	-	LYST	chr1	235850347	-	0.000770922	0.9992291
ENST00000313984	ENST00000389793	B3GALNT2	chr1	235647638	-	LYST	chr1	235850347	-	0.000778956	0.9992211

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Fusion Genomic Features for B3GALNT2-LYST

FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.

Hgene

Hchr

Hbp

Hstrand

Tgene

Tchr

Tbp

Tstrand

1-p

p (fusion gene breakpoint)

Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.

Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for B3GALNT2-LYST

Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr1:235647638/chr1:235850347)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.

Main function of each fusion partner protein. (from UniProt)

Hgene	Tgene
.	LYST Q99698
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.	FUNCTION: Adapter protein that regulates and/or fission of intracellular vesicles such as lysosomes (PubMed:11984006, PubMed:25216107). Might regulate trafficking of effectors involved in exocytosis (PubMed:25425525). In cytotoxic T-cells and natural killer (NK) cells, has role in the regulation of size, number and exocytosis of lytic granules (PubMed:26478006). In macrophages and dendritic cells, regulates phagosome maturation by controlling the conversion of early phagosomal compartments into late phagosomes (By similarity). In macrophages and dendritic cells, specifically involved in TLR3- and TLR4-induced production of pro-inflammatory cytokines by regulating the endosomal TLR3- TICAM1/TRIF and TLR4- TICAM1/TRIF signaling pathways (PubMed:27881733). {ECO:0000250\|UniProtKB:P97412, ECO:0000269\|PubMed:11984006, ECO:0000269\|PubMed:25216107, ECO:0000269\|PubMed:25425525, ECO:0000269\|PubMed:26478006, ECO:0000269\|PubMed:27881733}.

Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at
download page

* Minus value of BPloci means that the break pointn is located before the CDS.

- In-frame and retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

Hgene

B3GALNT2

chr1:235647638

chr1:235850347

ENST00000313984

1_6

226

327.0

Topological domain

Cytoplasmic

Hgene

B3GALNT2

chr1:235647638

chr1:235850347

ENST00000366600

1_6

185

501.0

Topological domain

Cytoplasmic

Hgene

B3GALNT2

chr1:235647638

chr1:235850347

ENST00000313984

7_23

226

327.0

Transmembrane

Helical%3B Signal-anchor for type II membrane protein

Hgene

B3GALNT2

chr1:235647638

chr1:235850347

ENST00000366600

7_23

185

501.0

Transmembrane

Helical%3B Signal-anchor for type II membrane protein

Tgene

LYST

chr1:235647638

chr1:235850347

ENST00000389793

3614_3653

3567

3802.0

Repeat

Note=WD 4

Tgene

LYST

chr1:235647638

chr1:235850347

ENST00000389793

3656_3699

3567

3802.0

Repeat

Note=WD 5

Tgene

LYST

chr1:235647638

chr1:235850347

ENST00000389793

3700_3744

3567

3802.0

Repeat

Note=WD 6

Tgene

LYST

chr1:235647638

chr1:235850347

ENST00000389793

3749_3788

3567

3802.0

Repeat

Note=WD 7

Tgene

LYST

chr1:235647638

chr1:235850347

ENST00000389794

3614_3653

3567

3802.0

Repeat

Note=WD 4

Tgene

LYST

chr1:235647638

chr1:235850347

ENST00000389794

3656_3699

3567

3802.0

Repeat

Note=WD 5

Tgene

LYST

chr1:235647638

chr1:235850347

ENST00000389794

3700_3744

3567

3802.0

Repeat

Note=WD 6

Tgene

LYST

chr1:235647638

chr1:235850347

ENST00000389794

3749_3788

3567

3802.0

Repeat

Note=WD 7

- In-frame and not-retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

Hgene

B3GALNT2

chr1:235647638

chr1:235850347

ENST00000313984

24_500

226

327.0

Topological domain

Lumenal

Hgene

B3GALNT2

chr1:235647638

chr1:235850347

ENST00000366600

24_500

185

501.0

Topological domain

Lumenal

Tgene

LYST

chr1:235647638

chr1:235850347

ENST00000389793

2448_2452

3567

3802.0

Compositional bias

Note=Poly-Leu

Tgene

LYST

chr1:235647638

chr1:235850347

ENST00000389793

31_36

3567

3802.0

Compositional bias

Note=Poly-Glu

Tgene

LYST

chr1:235647638

chr1:235850347

ENST00000389794

2448_2452

3567

3802.0

Compositional bias

Note=Poly-Leu

Tgene

LYST

chr1:235647638

chr1:235850347

ENST00000389794

31_36

3567

3802.0

Compositional bias

Note=Poly-Glu

Tgene

LYST

chr1:235647638

chr1:235850347

ENST00000389793

3009_3115

3567

3802.0

Domain

BEACH-type PH

Tgene

LYST

chr1:235647638

chr1:235850347

ENST00000389793

3120_3422

3567

3802.0

Domain

BEACH

Tgene

LYST

chr1:235647638

chr1:235850347

ENST00000389794

3009_3115

3567

3802.0

Domain

BEACH-type PH

Tgene

LYST

chr1:235647638

chr1:235850347

ENST00000389794

3120_3422

3567

3802.0

Domain

BEACH

Tgene

LYST

chr1:235647638

chr1:235850347

ENST00000389793

1582_1626

3567

3802.0

Repeat

Note=WD 2

Tgene

LYST

chr1:235647638

chr1:235850347

ENST00000389793

3563_3602

3567

3802.0

Repeat

Note=WD 3

Tgene

LYST

chr1:235647638

chr1:235850347

ENST00000389793

662_700

3567

3802.0

Repeat

Note=WD 1

Tgene

LYST

chr1:235647638

chr1:235850347

ENST00000389794

1582_1626

3567

3802.0

Repeat

Note=WD 2

Tgene

LYST

chr1:235647638

chr1:235850347

ENST00000389794

3563_3602

3567

3802.0

Repeat

Note=WD 3

Tgene

LYST

chr1:235647638

chr1:235850347

ENST00000389794

662_700

3567

3802.0

Repeat

Note=WD 1

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Fusion Gene Sequence for B3GALNT2-LYST

For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.

>8661_8661_1_B3GALNT2-LYST_B3GALNT2_chr1_235647638_ENST00000313984_LYST_chr1_235850347_ENST00000389793_length(transcript)=3443nt_BP=848nt
GGAGGAGCGGGGCCGGGAGCTGCGAGGAGCCCTCCAGACGTCGCCGAGCGCGAGGGCGGGCGTGCTCGGAGTGGTCGCTCGTCAGCCGCC
GCCCCTCAGTCTCCGCACTTGCAGGTCCCCTCCCTCTCCGCCGGGACGCGGGAGAGCCCGGCTCGCGGCGGGGGCGGCCAATGCGAAACT
GGCTGGTGCTGCTGTGCCCGTGTGTGCTCGGGGCCGCGCTGCACCTCTGGCTGCGGCTGCGCTCCCCGCCGCCCGCCTGCGCCTCCGGGG
CCGGCCCTGCAGGTGGAGTCTCACTCTTGTTGCCCAGGCTGGAGTGCAATGGCGCGGTCTCGGCTCACCCCAACCTCCACCTCCCGGGTT
CAAGAGATTCTCCTGCCTCAGCCTCCCAAGTAGCTGGGATAACAGATCAGTTGGCCTTATTTCCTCAGTGGAAATCTACTCACTATGATG
TGGTAGTTGGCGTGTTGTCAGCTCGCAATAACCATGAACTTCGAAACGTGATAAGAAGCACCTGGATGAGACATTTGCTACAGCATCCCA
CATTAAGTCAACGTGTGCTTGTGAAGTTCATAATAGGTGCTCATGGCTGTGAAGTGCCTGTGGAAGACAGGGAAGATCCTTATTCCTGTA
AACTACTCAACATCACAAATCCAGTTTTGAATCAGGAAATTGAAGCGTTCAGTCTGTCCGAAGACACTTCATCGGGGCTGCCTGAGGATC
GAGTTGTCAGCGTGAGTTTCCGAGTTCTCTACCCCATCGTTATTACCAGTCTTGGAGTGTTCTACGATGCCAATGATGTGGGTTTCCAGA
GGAACATCACTGTCAAACTTTATCAGGCAGAACAAGAGGTGACTAGTTGTGCTTGGGTGCCTGACAGTTGCCAGCTGTTTACTGGAAGCA
AATGCGGTGTCATCACAGCCTACACAAACAGATTTACAAGCAGCACGCCATCAGAAATAGAAATGGAGACTCAAATACATCTCTATGGTC
ACACAGAAGAGATAACCAGCTTATTTGTTTGCAAACCATACAGTATACTGATAAGTGTGAGCAGAGACGGAACCTGCATCATATGGGATT
TAAACAGGTTATGCTATGTACAAAGTCTGGCGGGACACAAAAGCCCTGTCACAGCTGTCTCTGCCAGTGAAACCTCAGGTGATATTGCTA
CTGTGTGTGATTCAGCTGGCGGAGGCAGTGACCTCAGACTCTGGACGGTGAACGGGGATCTCGTTGGACATGTCCACTGCAGGGAGATCA
TCTGTTCCGTGGCTTTCTCCAACCAGCCTGAGGGAGTATCTATCAATGTAATCGCTGGGGGATTAGAAAATGGAATTGTAAGGTTATGGA
GCACATGGGACTTAAAGCCTGTGAGAGAAATTACATTTCCCAAATCAAATAAGCCCATCATCAGCCTTACATTTTCTTGTGATGGCCACC
ATTTGTACACAGCAAACAGTGATGGGACCGTGATTGCCTGGTGTCGGAAGGACCAGCAGCGCTTGAAACAGCCAATGTTCTATTCCTTCC
TTAGCAGCTATGCAGCCGGGTGAATGCGAATGAACTTCACGTTCTCCAAAGCACTTTAACTCCAAACTAGATTTGTTGACTTCACCAGTT
TTAGGAGGTTGAACCTAAAGAAATGGATGACTGGACAAACCATCCAAATAATGATAAAGTCTATTCATCTGCACAAAATTCTGAAGAGTC
ACATGATCCTAAGAGGAAAGTTCTGTTCTATTTTAGTGATAATCTGGAAGATTGTGTCAATATGCACTAGCCAACAAGTTTTAAGCCTCG
CATGGTACATTAAAATGATATTCTTAAAATTTTTTCCCACCAAGGTATTCCAAAGAAAATATTAAGGTCTCCCCTTTTTCTATGATTCCA
AAAGGACCAGTAGAATTTAAATTGGTTGGTTGATTGTTTATATAAAACACACTAAAATTATATTTTAAAAGTTTACTGCCATGAAATACT
CCTCCCACCACACACACATGCTCCAAAAGAGGAAAGAAAAAAAGATAATTTTTAGGACTTGATAATTGCTTTCTTTGAGAAGCAAATTAT
TCAGTAGGTGCCTCTGTACCAAATATTTTATGGAATATCTAAATACTAAAATAAACTATGAATGAATCTCAAAATTAGGCAGTTTTTGCC
AGTTGCTTTCTTAGCTCAAAGGAGAACCAGAATTTTTTTGACAGCCACAAACAAGAATACAGGTATCTTGGATTTCAGACACATTCTGTT
TCTTCATAAAAATTTTACTTAAAATCTGTAACGCTAGATATTGACTATCCTTAGTTGAGTCACTGAGGTTTAAACACAATGGTAAGTCTT
AAAGTCTGCTATTTACAGAGCATTGAATCTGTACCAATTTGCAATAGAAAGCCTTCAGTATGCAAGAAGTTTGCATGGGTATTAAGAACA
CAGCCTAAATAAGGCATTTGATCTAATCTGCAGGAAGAATTTTCTTCCCCAAAACAGAATTATAAAAGCTTACTTTAAACAGGAGGCAGA
ATAATTCTTTTAGGAAACCATTTCATTCTGTTTCTACTAACCTATACCATCTGAGAATTCTAGGAAGAATAATAAAATCTCGTGTATTCC
ACAGCAAACTTACATACCATAAAGACAGAATTCCTAAACATCTTGGAGCCGTCTGTCTCTCCCATATGATGGCTGTCTGTATATTTTTAC
TTGGGGTGCTGCTTTATTGGCTTTGAAAACACTGTCAGATAAGCTCAGTAATATGTTACCATGGGATAAAAATATGTATCCCTGCCTAAG
AATAACTTGTGCATTTGTTATGGAAATTTAATTCATATGGTGTTTACAGTACTACTTTTGTAACTTCCAGACTTTCTAAAACATTCTGCT
TAAAAACCATATAAAATATAATTCCAAAGTCTCTGCTGTCAAGATAGATTCGAGAGAAAGCACGTGGCCATGTATGCTTTAACCTTAAAC
TGCATACACATGTAGTGATACCTAGGCTGCATTTAGATCACCGTGTGCTCAGGCCAGGTGTGAATCCTGAGGTCCATGGAGGTGCAGAGA
TGAGATTACTCCTATTCACGTTGAAGTGATTTGCTTTGTTAACAAAAAATTGCAGCTATTGTCTAGCTTTCATTTTTTTACTGAGAACTT
TAAATTAGTCCCCTATTAGAATAGGGTTGCTACTCATCTTTTTTTAAAAACCGAATTTCATCATTTATCTAAAGAGAAAATATGCAGAAT
AACTGGTCTTGTTAAGAGTGCAATATTATATTTTTATGTAAAAATAAAAATTAATTTGGGGGGATTATTTATTCAGCATGAAACCTAATA
TGTATATGTTTGAAATACTTCATAATGTGCATGTTGTAGCAAACATTTCTGTAAATTATCACAAGCTCTGTTACCTTTATATACACTGCC

>8661_8661_1_B3GALNT2-LYST_B3GALNT2_chr1_235647638_ENST00000313984_LYST_chr1_235850347_ENST00000389793_length(amino acids)=460AA_BP=40
MRNWLVLLCPCVLGAALHLWLRLRSPPPACASGAGPAGGVSLLLPRLECNGAVSAHPNLHLPGSRDSPASASQVAGITDQLALFPQWKST
HYDVVVGVLSARNNHELRNVIRSTWMRHLLQHPTLSQRVLVKFIIGAHGCEVPVEDREDPYSCKLLNITNPVLNQEIEAFSLSEDTSSGL
PEDRVVSVSFRVLYPIVITSLGVFYDANDVGFQRNITVKLYQAEQEVTSCAWVPDSCQLFTGSKCGVITAYTNRFTSSTPSEIEMETQIH
LYGHTEEITSLFVCKPYSILISVSRDGTCIIWDLNRLCYVQSLAGHKSPVTAVSASETSGDIATVCDSAGGGSDLRLWTVNGDLVGHVHC
REIICSVAFSNQPEGVSINVIAGGLENGIVRLWSTWDLKPVREITFPKSNKPIISLTFSCDGHHLYTANSDGTVIAWCRKDQQRLKQPMF

--------------------------------------------------------------
>8661_8661_2_B3GALNT2-LYST_B3GALNT2_chr1_235647638_ENST00000313984_LYST_chr1_235850347_ENST00000389794_length(transcript)=3452nt_BP=848nt
GGAGGAGCGGGGCCGGGAGCTGCGAGGAGCCCTCCAGACGTCGCCGAGCGCGAGGGCGGGCGTGCTCGGAGTGGTCGCTCGTCAGCCGCC
GCCCCTCAGTCTCCGCACTTGCAGGTCCCCTCCCTCTCCGCCGGGACGCGGGAGAGCCCGGCTCGCGGCGGGGGCGGCCAATGCGAAACT
GGCTGGTGCTGCTGTGCCCGTGTGTGCTCGGGGCCGCGCTGCACCTCTGGCTGCGGCTGCGCTCCCCGCCGCCCGCCTGCGCCTCCGGGG
CCGGCCCTGCAGGTGGAGTCTCACTCTTGTTGCCCAGGCTGGAGTGCAATGGCGCGGTCTCGGCTCACCCCAACCTCCACCTCCCGGGTT
CAAGAGATTCTCCTGCCTCAGCCTCCCAAGTAGCTGGGATAACAGATCAGTTGGCCTTATTTCCTCAGTGGAAATCTACTCACTATGATG
TGGTAGTTGGCGTGTTGTCAGCTCGCAATAACCATGAACTTCGAAACGTGATAAGAAGCACCTGGATGAGACATTTGCTACAGCATCCCA
CATTAAGTCAACGTGTGCTTGTGAAGTTCATAATAGGTGCTCATGGCTGTGAAGTGCCTGTGGAAGACAGGGAAGATCCTTATTCCTGTA
AACTACTCAACATCACAAATCCAGTTTTGAATCAGGAAATTGAAGCGTTCAGTCTGTCCGAAGACACTTCATCGGGGCTGCCTGAGGATC
GAGTTGTCAGCGTGAGTTTCCGAGTTCTCTACCCCATCGTTATTACCAGTCTTGGAGTGTTCTACGATGCCAATGATGTGGGTTTCCAGA
GGAACATCACTGTCAAACTTTATCAGGCAGAACAAGAGGTGACTAGTTGTGCTTGGGTGCCTGACAGTTGCCAGCTGTTTACTGGAAGCA
AATGCGGTGTCATCACAGCCTACACAAACAGATTTACAAGCAGCACGCCATCAGAAATAGAAATGGAGACTCAAATACATCTCTATGGTC
ACACAGAAGAGATAACCAGCTTATTTGTTTGCAAACCATACAGTATACTGATAAGTGTGAGCAGAGACGGAACCTGCATCATATGGGATT
TAAACAGGTTATGCTATGTACAAAGTCTGGCGGGACACAAAAGCCCTGTCACAGCTGTCTCTGCCAGTGAAACCTCAGGTGATATTGCTA
CTGTGTGTGATTCAGCTGGCGGAGGCAGTGACCTCAGACTCTGGACGGTGAACGGGGATCTCGTTGGACATGTCCACTGCAGGGAGATCA
TCTGTTCCGTGGCTTTCTCCAACCAGCCTGAGGGAGTATCTATCAATGTAATCGCTGGGGGATTAGAAAATGGAATTGTAAGGTTATGGA
GCACATGGGACTTAAAGCCTGTGAGAGAAATTACATTTCCCAAATCAAATAAGCCCATCATCAGCCTTACATTTTCTTGTGATGGCCACC
ATTTGTACACAGCAAACAGTGATGGGACCGTGATTGCCTGGTGTCGGAAGGACCAGCAGCGCTTGAAACAGCCAATGTTCTATTCCTTCC
TTAGCAGCTATGCAGCCGGGTGAATGCGAATGAACTTCACGTTCTCCAAAGCACTTTAACTCCAAACTAGATTTGTTGACTTCACCAGTT
TTAGGAGGTTGAACCTAAAGAAATGGATGACTGGACAAACCATCCAAATAATGATAAAGTCTATTCATCTGCACAAAATTCTGAAGAGTC
ACATGATCCTAAGAGGAAAGTTCTGTTCTATTTTAGTGATAATCTGGAAGATTGTGTCAATATGCACTAGCCAACAAGTTTTAAGCCTCG
CATGGTACATTAAAATGATATTCTTAAAATTTTTTCCCACCAAGGTATTCCAAAGAAAATATTAAGGTCTCCCCTTTTTCTATGATTCCA
AAAGGACCAGTAGAATTTAAATTGGTTGGTTGATTGTTTATATAAAACACACTAAAATTATATTTTAAAAGTTTACTGCCATGAAATACT
CCTCCCACCACACACACATGCTCCAAAAGAGGAAAGAAAAAAAGATAATTTTTAGGACTTGATAATTGCTTTCTTTGAGAAGCAAATTAT
TCAGTAGGTGCCTCTGTACCAAATATTTTATGGAATATCTAAATACTAAAATAAACTATGAATGAATCTCAAAATTAGGCAGTTTTTGCC
AGTTGCTTTCTTAGCTCAAAGGAGAACCAGAATTTTTTTGACAGCCACAAACAAGAATACAGGTATCTTGGATTTCAGACACATTCTGTT
TCTTCATAAAAATTTTACTTAAAATCTGTAACGCTAGATATTGACTATCCTTAGTTGAGTCACTGAGGTTTAAACACAATGGTAAGTCTT
AAAGTCTGCTATTTACAGAGCATTGAATCTGTACCAATTTGCAATAGAAAGCCTTCAGTATGCAAGAAGTTTGCATGGGTATTAAGAACA
CAGCCTAAATAAGGCATTTGATCTAATCTGCAGGAAGAATTTTCTTCCCCAAAACAGAATTATAAAAGCTTACTTTAAACAGGAGGCAGA
ATAATTCTTTTAGGAAACCATTTCATTCTGTTTCTACTAACCTATACCATCTGAGAATTCTAGGAAGAATAATAAAATCTCGTGTATTCC
ACAGCAAACTTACATACCATAAAGACAGAATTCCTAAACATCTTGGAGCCGTCTGTCTCTCCCATATGATGGCTGTCTGTATATTTTTAC
TTGGGGTGCTGCTTTATTGGCTTTGAAAACACTGTCAGATAAGCTCAGTAATATGTTACCATGGGATAAAAATATGTATCCCTGCCTAAG
AATAACTTGTGCATTTGTTATGGAAATTTAATTCATATGGTGTTTACAGTACTACTTTTGTAACTTCCAGACTTTCTAAAACATTCTGCT
TAAAAACCATATAAAATATAATTCCAAAGTCTCTGCTGTCAAGATAGATTCGAGAGAAAGCACGTGGCCATGTATGCTTTAACCTTAAAC
TGCATACACATGTAGTGATACCTAGGCTGCATTTAGATCACCGTGTGCTCAGGCCAGGTGTGAATCCTGAGGTCCATGGAGGTGCAGAGA
TGAGATTACTCCTATTCACGTTGAAGTGATTTGCTTTGTTAACAAAAAATTGCAGCTATTGTCTAGCTTTCATTTTTTTACTGAGAACTT
TAAATTAGTCCCCTATTAGAATAGGGTTGCTACTCATCTTTTTTTAAAAACCGAATTTCATCATTTATCTAAAGAGAAAATATGCAGAAT
AACTGGTCTTGTTAAGAGTGCAATATTATATTTTTATGTAAAAATAAAAATTAATTTGGGGGGATTATTTATTCAGCATGAAACCTAATA
TGTATATGTTTGAAATACTTCATAATGTGCATGTTGTAGCAAACATTTCTGTAAATTATCACAAGCTCTGTTACCTTTATATACACTGCC

>8661_8661_2_B3GALNT2-LYST_B3GALNT2_chr1_235647638_ENST00000313984_LYST_chr1_235850347_ENST00000389794_length(amino acids)=460AA_BP=40
MRNWLVLLCPCVLGAALHLWLRLRSPPPACASGAGPAGGVSLLLPRLECNGAVSAHPNLHLPGSRDSPASASQVAGITDQLALFPQWKST
HYDVVVGVLSARNNHELRNVIRSTWMRHLLQHPTLSQRVLVKFIIGAHGCEVPVEDREDPYSCKLLNITNPVLNQEIEAFSLSEDTSSGL
PEDRVVSVSFRVLYPIVITSLGVFYDANDVGFQRNITVKLYQAEQEVTSCAWVPDSCQLFTGSKCGVITAYTNRFTSSTPSEIEMETQIH
LYGHTEEITSLFVCKPYSILISVSRDGTCIIWDLNRLCYVQSLAGHKSPVTAVSASETSGDIATVCDSAGGGSDLRLWTVNGDLVGHVHC
REIICSVAFSNQPEGVSINVIAGGLENGIVRLWSTWDLKPVREITFPKSNKPIISLTFSCDGHHLYTANSDGTVIAWCRKDQQRLKQPMF

--------------------------------------------------------------
>8661_8661_3_B3GALNT2-LYST_B3GALNT2_chr1_235647638_ENST00000366600_LYST_chr1_235850347_ENST00000389793_length(transcript)=3379nt_BP=784nt
AGGCGGAGGGGGCGGGGCTTCGGCCGGCTAAGCCGCGGCCACCCGCGGTCTGAGGGACCGGAGGAGCGGGGCCGGGAGCTGCGAGGAGCC
CTCCAGACGTCGCCGAGCGCGAGGGCGGGCGTGCTCGGAGTGGTCGCTCGTCAGCCGCCGCCCCTCAGTCTCCGCACTTGCAGGTCCCCT
CCCTCTCCGCCGGGACGCGGGAGAGCCCGGCTCGCGGCGGGGGCGGCCAATGCGAAACTGGCTGGTGCTGCTGTGCCCGTGTGTGCTCGG
GGCCGCGCTGCACCTCTGGCTGCGGCTGCGCTCCCCGCCGCCCGCCTGCGCCTCCGGGGCCGGCCCTGCAGATCAGTTGGCCTTATTTCC
TCAGTGGAAATCTACTCACTATGATGTGGTAGTTGGCGTGTTGTCAGCTCGCAATAACCATGAACTTCGAAACGTGATAAGAAGCACCTG
GATGAGACATTTGCTACAGCATCCCACATTAAGTCAACGTGTGCTTGTGAAGTTCATAATAGGTGCTCATGGCTGTGAAGTGCCTGTGGA
AGACAGGGAAGATCCTTATTCCTGTAAACTACTCAACATCACAAATCCAGTTTTGAATCAGGAAATTGAAGCGTTCAGTCTGTCCGAAGA
CACTTCATCGGGGCTGCCTGAGGATCGAGTTGTCAGCGTGAGTTTCCGAGTTCTCTACCCCATCGTTATTACCAGTCTTGGAGTGTTCTA
CGATGCCAATGATGTGGGTTTCCAGAGGAACATCACTGTCAAACTTTATCAGGCAGAACAAGAGGTGACTAGTTGTGCTTGGGTGCCTGA
CAGTTGCCAGCTGTTTACTGGAAGCAAATGCGGTGTCATCACAGCCTACACAAACAGATTTACAAGCAGCACGCCATCAGAAATAGAAAT
GGAGACTCAAATACATCTCTATGGTCACACAGAAGAGATAACCAGCTTATTTGTTTGCAAACCATACAGTATACTGATAAGTGTGAGCAG
AGACGGAACCTGCATCATATGGGATTTAAACAGGTTATGCTATGTACAAAGTCTGGCGGGACACAAAAGCCCTGTCACAGCTGTCTCTGC
CAGTGAAACCTCAGGTGATATTGCTACTGTGTGTGATTCAGCTGGCGGAGGCAGTGACCTCAGACTCTGGACGGTGAACGGGGATCTCGT
TGGACATGTCCACTGCAGGGAGATCATCTGTTCCGTGGCTTTCTCCAACCAGCCTGAGGGAGTATCTATCAATGTAATCGCTGGGGGATT
AGAAAATGGAATTGTAAGGTTATGGAGCACATGGGACTTAAAGCCTGTGAGAGAAATTACATTTCCCAAATCAAATAAGCCCATCATCAG
CCTTACATTTTCTTGTGATGGCCACCATTTGTACACAGCAAACAGTGATGGGACCGTGATTGCCTGGTGTCGGAAGGACCAGCAGCGCTT
GAAACAGCCAATGTTCTATTCCTTCCTTAGCAGCTATGCAGCCGGGTGAATGCGAATGAACTTCACGTTCTCCAAAGCACTTTAACTCCA
AACTAGATTTGTTGACTTCACCAGTTTTAGGAGGTTGAACCTAAAGAAATGGATGACTGGACAAACCATCCAAATAATGATAAAGTCTAT
TCATCTGCACAAAATTCTGAAGAGTCACATGATCCTAAGAGGAAAGTTCTGTTCTATTTTAGTGATAATCTGGAAGATTGTGTCAATATG
CACTAGCCAACAAGTTTTAAGCCTCGCATGGTACATTAAAATGATATTCTTAAAATTTTTTCCCACCAAGGTATTCCAAAGAAAATATTA
AGGTCTCCCCTTTTTCTATGATTCCAAAAGGACCAGTAGAATTTAAATTGGTTGGTTGATTGTTTATATAAAACACACTAAAATTATATT
TTAAAAGTTTACTGCCATGAAATACTCCTCCCACCACACACACATGCTCCAAAAGAGGAAAGAAAAAAAGATAATTTTTAGGACTTGATA
ATTGCTTTCTTTGAGAAGCAAATTATTCAGTAGGTGCCTCTGTACCAAATATTTTATGGAATATCTAAATACTAAAATAAACTATGAATG
AATCTCAAAATTAGGCAGTTTTTGCCAGTTGCTTTCTTAGCTCAAAGGAGAACCAGAATTTTTTTGACAGCCACAAACAAGAATACAGGT
ATCTTGGATTTCAGACACATTCTGTTTCTTCATAAAAATTTTACTTAAAATCTGTAACGCTAGATATTGACTATCCTTAGTTGAGTCACT
GAGGTTTAAACACAATGGTAAGTCTTAAAGTCTGCTATTTACAGAGCATTGAATCTGTACCAATTTGCAATAGAAAGCCTTCAGTATGCA
AGAAGTTTGCATGGGTATTAAGAACACAGCCTAAATAAGGCATTTGATCTAATCTGCAGGAAGAATTTTCTTCCCCAAAACAGAATTATA
AAAGCTTACTTTAAACAGGAGGCAGAATAATTCTTTTAGGAAACCATTTCATTCTGTTTCTACTAACCTATACCATCTGAGAATTCTAGG
AAGAATAATAAAATCTCGTGTATTCCACAGCAAACTTACATACCATAAAGACAGAATTCCTAAACATCTTGGAGCCGTCTGTCTCTCCCA
TATGATGGCTGTCTGTATATTTTTACTTGGGGTGCTGCTTTATTGGCTTTGAAAACACTGTCAGATAAGCTCAGTAATATGTTACCATGG
GATAAAAATATGTATCCCTGCCTAAGAATAACTTGTGCATTTGTTATGGAAATTTAATTCATATGGTGTTTACAGTACTACTTTTGTAAC
TTCCAGACTTTCTAAAACATTCTGCTTAAAAACCATATAAAATATAATTCCAAAGTCTCTGCTGTCAAGATAGATTCGAGAGAAAGCACG
TGGCCATGTATGCTTTAACCTTAAACTGCATACACATGTAGTGATACCTAGGCTGCATTTAGATCACCGTGTGCTCAGGCCAGGTGTGAA
TCCTGAGGTCCATGGAGGTGCAGAGATGAGATTACTCCTATTCACGTTGAAGTGATTTGCTTTGTTAACAAAAAATTGCAGCTATTGTCT
AGCTTTCATTTTTTTACTGAGAACTTTAAATTAGTCCCCTATTAGAATAGGGTTGCTACTCATCTTTTTTTAAAAACCGAATTTCATCAT
TTATCTAAAGAGAAAATATGCAGAATAACTGGTCTTGTTAAGAGTGCAATATTATATTTTTATGTAAAAATAAAAATTAATTTGGGGGGA
TTATTTATTCAGCATGAAACCTAATATGTATATGTTTGAAATACTTCATAATGTGCATGTTGTAGCAAACATTTCTGTAAATTATCACAA

>8661_8661_3_B3GALNT2-LYST_B3GALNT2_chr1_235647638_ENST00000366600_LYST_chr1_235850347_ENST00000389793_length(amino acids)=479AA_BP=245
MRDRRSGAGSCEEPSRRRRARGRACSEWSLVSRRPSVSALAGPLPLRRDAGEPGSRRGRPMRNWLVLLCPCVLGAALHLWLRLRSPPPAC
ASGAGPADQLALFPQWKSTHYDVVVGVLSARNNHELRNVIRSTWMRHLLQHPTLSQRVLVKFIIGAHGCEVPVEDREDPYSCKLLNITNP
VLNQEIEAFSLSEDTSSGLPEDRVVSVSFRVLYPIVITSLGVFYDANDVGFQRNITVKLYQAEQEVTSCAWVPDSCQLFTGSKCGVITAY
TNRFTSSTPSEIEMETQIHLYGHTEEITSLFVCKPYSILISVSRDGTCIIWDLNRLCYVQSLAGHKSPVTAVSASETSGDIATVCDSAGG
GSDLRLWTVNGDLVGHVHCREIICSVAFSNQPEGVSINVIAGGLENGIVRLWSTWDLKPVREITFPKSNKPIISLTFSCDGHHLYTANSD

--------------------------------------------------------------
>8661_8661_4_B3GALNT2-LYST_B3GALNT2_chr1_235647638_ENST00000366600_LYST_chr1_235850347_ENST00000389794_length(transcript)=3388nt_BP=784nt
AGGCGGAGGGGGCGGGGCTTCGGCCGGCTAAGCCGCGGCCACCCGCGGTCTGAGGGACCGGAGGAGCGGGGCCGGGAGCTGCGAGGAGCC
CTCCAGACGTCGCCGAGCGCGAGGGCGGGCGTGCTCGGAGTGGTCGCTCGTCAGCCGCCGCCCCTCAGTCTCCGCACTTGCAGGTCCCCT
CCCTCTCCGCCGGGACGCGGGAGAGCCCGGCTCGCGGCGGGGGCGGCCAATGCGAAACTGGCTGGTGCTGCTGTGCCCGTGTGTGCTCGG
GGCCGCGCTGCACCTCTGGCTGCGGCTGCGCTCCCCGCCGCCCGCCTGCGCCTCCGGGGCCGGCCCTGCAGATCAGTTGGCCTTATTTCC
TCAGTGGAAATCTACTCACTATGATGTGGTAGTTGGCGTGTTGTCAGCTCGCAATAACCATGAACTTCGAAACGTGATAAGAAGCACCTG
GATGAGACATTTGCTACAGCATCCCACATTAAGTCAACGTGTGCTTGTGAAGTTCATAATAGGTGCTCATGGCTGTGAAGTGCCTGTGGA
AGACAGGGAAGATCCTTATTCCTGTAAACTACTCAACATCACAAATCCAGTTTTGAATCAGGAAATTGAAGCGTTCAGTCTGTCCGAAGA
CACTTCATCGGGGCTGCCTGAGGATCGAGTTGTCAGCGTGAGTTTCCGAGTTCTCTACCCCATCGTTATTACCAGTCTTGGAGTGTTCTA
CGATGCCAATGATGTGGGTTTCCAGAGGAACATCACTGTCAAACTTTATCAGGCAGAACAAGAGGTGACTAGTTGTGCTTGGGTGCCTGA
CAGTTGCCAGCTGTTTACTGGAAGCAAATGCGGTGTCATCACAGCCTACACAAACAGATTTACAAGCAGCACGCCATCAGAAATAGAAAT
GGAGACTCAAATACATCTCTATGGTCACACAGAAGAGATAACCAGCTTATTTGTTTGCAAACCATACAGTATACTGATAAGTGTGAGCAG
AGACGGAACCTGCATCATATGGGATTTAAACAGGTTATGCTATGTACAAAGTCTGGCGGGACACAAAAGCCCTGTCACAGCTGTCTCTGC
CAGTGAAACCTCAGGTGATATTGCTACTGTGTGTGATTCAGCTGGCGGAGGCAGTGACCTCAGACTCTGGACGGTGAACGGGGATCTCGT
TGGACATGTCCACTGCAGGGAGATCATCTGTTCCGTGGCTTTCTCCAACCAGCCTGAGGGAGTATCTATCAATGTAATCGCTGGGGGATT
AGAAAATGGAATTGTAAGGTTATGGAGCACATGGGACTTAAAGCCTGTGAGAGAAATTACATTTCCCAAATCAAATAAGCCCATCATCAG
CCTTACATTTTCTTGTGATGGCCACCATTTGTACACAGCAAACAGTGATGGGACCGTGATTGCCTGGTGTCGGAAGGACCAGCAGCGCTT
GAAACAGCCAATGTTCTATTCCTTCCTTAGCAGCTATGCAGCCGGGTGAATGCGAATGAACTTCACGTTCTCCAAAGCACTTTAACTCCA
AACTAGATTTGTTGACTTCACCAGTTTTAGGAGGTTGAACCTAAAGAAATGGATGACTGGACAAACCATCCAAATAATGATAAAGTCTAT
TCATCTGCACAAAATTCTGAAGAGTCACATGATCCTAAGAGGAAAGTTCTGTTCTATTTTAGTGATAATCTGGAAGATTGTGTCAATATG
CACTAGCCAACAAGTTTTAAGCCTCGCATGGTACATTAAAATGATATTCTTAAAATTTTTTCCCACCAAGGTATTCCAAAGAAAATATTA
AGGTCTCCCCTTTTTCTATGATTCCAAAAGGACCAGTAGAATTTAAATTGGTTGGTTGATTGTTTATATAAAACACACTAAAATTATATT
TTAAAAGTTTACTGCCATGAAATACTCCTCCCACCACACACACATGCTCCAAAAGAGGAAAGAAAAAAAGATAATTTTTAGGACTTGATA
ATTGCTTTCTTTGAGAAGCAAATTATTCAGTAGGTGCCTCTGTACCAAATATTTTATGGAATATCTAAATACTAAAATAAACTATGAATG
AATCTCAAAATTAGGCAGTTTTTGCCAGTTGCTTTCTTAGCTCAAAGGAGAACCAGAATTTTTTTGACAGCCACAAACAAGAATACAGGT
ATCTTGGATTTCAGACACATTCTGTTTCTTCATAAAAATTTTACTTAAAATCTGTAACGCTAGATATTGACTATCCTTAGTTGAGTCACT
GAGGTTTAAACACAATGGTAAGTCTTAAAGTCTGCTATTTACAGAGCATTGAATCTGTACCAATTTGCAATAGAAAGCCTTCAGTATGCA
AGAAGTTTGCATGGGTATTAAGAACACAGCCTAAATAAGGCATTTGATCTAATCTGCAGGAAGAATTTTCTTCCCCAAAACAGAATTATA
AAAGCTTACTTTAAACAGGAGGCAGAATAATTCTTTTAGGAAACCATTTCATTCTGTTTCTACTAACCTATACCATCTGAGAATTCTAGG
AAGAATAATAAAATCTCGTGTATTCCACAGCAAACTTACATACCATAAAGACAGAATTCCTAAACATCTTGGAGCCGTCTGTCTCTCCCA
TATGATGGCTGTCTGTATATTTTTACTTGGGGTGCTGCTTTATTGGCTTTGAAAACACTGTCAGATAAGCTCAGTAATATGTTACCATGG
GATAAAAATATGTATCCCTGCCTAAGAATAACTTGTGCATTTGTTATGGAAATTTAATTCATATGGTGTTTACAGTACTACTTTTGTAAC
TTCCAGACTTTCTAAAACATTCTGCTTAAAAACCATATAAAATATAATTCCAAAGTCTCTGCTGTCAAGATAGATTCGAGAGAAAGCACG
TGGCCATGTATGCTTTAACCTTAAACTGCATACACATGTAGTGATACCTAGGCTGCATTTAGATCACCGTGTGCTCAGGCCAGGTGTGAA
TCCTGAGGTCCATGGAGGTGCAGAGATGAGATTACTCCTATTCACGTTGAAGTGATTTGCTTTGTTAACAAAAAATTGCAGCTATTGTCT
AGCTTTCATTTTTTTACTGAGAACTTTAAATTAGTCCCCTATTAGAATAGGGTTGCTACTCATCTTTTTTTAAAAACCGAATTTCATCAT
TTATCTAAAGAGAAAATATGCAGAATAACTGGTCTTGTTAAGAGTGCAATATTATATTTTTATGTAAAAATAAAAATTAATTTGGGGGGA
TTATTTATTCAGCATGAAACCTAATATGTATATGTTTGAAATACTTCATAATGTGCATGTTGTAGCAAACATTTCTGTAAATTATCACAA

>8661_8661_4_B3GALNT2-LYST_B3GALNT2_chr1_235647638_ENST00000366600_LYST_chr1_235850347_ENST00000389794_length(amino acids)=479AA_BP=245
MRDRRSGAGSCEEPSRRRRARGRACSEWSLVSRRPSVSALAGPLPLRRDAGEPGSRRGRPMRNWLVLLCPCVLGAALHLWLRLRSPPPAC
ASGAGPADQLALFPQWKSTHYDVVVGVLSARNNHELRNVIRSTWMRHLLQHPTLSQRVLVKFIIGAHGCEVPVEDREDPYSCKLLNITNP
VLNQEIEAFSLSEDTSSGLPEDRVVSVSFRVLYPIVITSLGVFYDANDVGFQRNITVKLYQAEQEVTSCAWVPDSCQLFTGSKCGVITAY
TNRFTSSTPSEIEMETQIHLYGHTEEITSLFVCKPYSILISVSRDGTCIIWDLNRLCYVQSLAGHKSPVTAVSASETSGDIATVCDSAGG
GSDLRLWTVNGDLVGHVHCREIICSVAFSNQPEGVSINVIAGGLENGIVRLWSTWDLKPVREITFPKSNKPIISLTFSCDGHHLYTANSD

--------------------------------------------------------------

Top

Fusion Gene PPI Analysis for B3GALNT2-LYST

Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in
ChiPPI page.

Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)

Hgene

Hgene's interactors

Tgene

Tgene's interactors

- Retained PPIs in in-frame fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Still interaction with

- Lost PPIs in in-frame fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Interaction lost with

- Retained PPIs, but lost function due to frame-shift fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Interaction lost with

Top

Related Drugs for B3GALNT2-LYST

Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)

Partner

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

Top

Related Diseases for B3GALNT2-LYST

Diseases associated with fusion partners.
(DisGeNet 4.0)

Partner

Gene

Disease ID

Disease name

# pubmeds

Source