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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:SRSF7-HNRNPLL (FusionGDB2 ID:86647)

Fusion Gene Summary for SRSF7-HNRNPLL

check button Fusion gene summary
Fusion gene informationFusion gene name: SRSF7-HNRNPLL
Fusion gene ID: 86647
HgeneTgene
Gene symbol

SRSF7

HNRNPLL

Gene ID

6432

92906

Gene nameserine and arginine rich splicing factor 7heterogeneous nuclear ribonucleoprotein L like
Synonyms9G8|AAG3|SFRS7HNRPLL|SRRF
Cytomap

2p22.1

2p22.1

Type of geneprotein-codingprotein-coding
Descriptionserine/arginine-rich splicing factor 7SR splicing factor 7aging-associated protein 3splicing factor 9G8splicing factor, arginine/serine-rich 7, 35kDaheterogeneous nuclear ribonucleoprotein L-likestromal RNA regulating factor
Modification date2020031320200327
UniProtAcc.

Q8WVV9

Ensembl transtripts involved in fusion geneENST00000313117, ENST00000409276, 
ENST00000446327, 		ENST00000498516, 
ENST00000358367, ENST00000378915, 
ENST00000409328, ENST00000449105, 
ENST00000608859, ENST00000409636, 
ENST00000410076, 
Fusion gene scores* DoF score4 X 4 X 2=326 X 7 X 4=168
# samples 46
** MAII scorelog2(4/32*10)=0.321928094887362
effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs).
DoF>8 and MAII>0		log2(6/168*10)=-1.48542682717024
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: SRSF7 [Title/Abstract] AND HNRNPLL [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointSRSF7(38973286)-HNRNPLL(38829742), # samples:2
Anticipated loss of major functional domain due to fusion event.SRSF7-HNRNPLL seems lost the major protein functional domain in Hgene partner, which is a essential gene due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneSRSF7

GO:0008380

RNA splicing

8013463

HgeneSRSF7

GO:0048025

negative regulation of mRNA splicing, via spliceosome

15009664

TgeneHNRNPLL

GO:0033120

positive regulation of RNA splicing

18669861


check buttonFusion gene breakpoints across SRSF7 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across HNRNPLL (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4CESCTCGA-DS-A1O9-01ASRSF7chr2

38973286

-HNRNPLLchr2

38829742

-
ChimerDB4CESCTCGA-DS-A1O9SRSF7chr2

38973286

-HNRNPLLchr2

38829742

-


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Fusion Gene ORF analysis for SRSF7-HNRNPLL

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-5UTRENST00000313117ENST00000498516SRSF7chr2

38973286

-HNRNPLLchr2

38829742

-
5CDS-5UTRENST00000409276ENST00000498516SRSF7chr2

38973286

-HNRNPLLchr2

38829742

-
Frame-shiftENST00000313117ENST00000358367SRSF7chr2

38973286

-HNRNPLLchr2

38829742

-
Frame-shiftENST00000313117ENST00000378915SRSF7chr2

38973286

-HNRNPLLchr2

38829742

-
Frame-shiftENST00000313117ENST00000409328SRSF7chr2

38973286

-HNRNPLLchr2

38829742

-
Frame-shiftENST00000313117ENST00000449105SRSF7chr2

38973286

-HNRNPLLchr2

38829742

-
Frame-shiftENST00000313117ENST00000608859SRSF7chr2

38973286

-HNRNPLLchr2

38829742

-
Frame-shiftENST00000409276ENST00000358367SRSF7chr2

38973286

-HNRNPLLchr2

38829742

-
Frame-shiftENST00000409276ENST00000378915SRSF7chr2

38973286

-HNRNPLLchr2

38829742

-
Frame-shiftENST00000409276ENST00000409328SRSF7chr2

38973286

-HNRNPLLchr2

38829742

-
Frame-shiftENST00000409276ENST00000449105SRSF7chr2

38973286

-HNRNPLLchr2

38829742

-
Frame-shiftENST00000409276ENST00000608859SRSF7chr2

38973286

-HNRNPLLchr2

38829742

-
In-frameENST00000313117ENST00000409636SRSF7chr2

38973286

-HNRNPLLchr2

38829742

-
In-frameENST00000313117ENST00000410076SRSF7chr2

38973286

-HNRNPLLchr2

38829742

-
In-frameENST00000409276ENST00000409636SRSF7chr2

38973286

-HNRNPLLchr2

38829742

-
In-frameENST00000409276ENST00000410076SRSF7chr2

38973286

-HNRNPLLchr2

38829742

-
intron-3CDSENST00000446327ENST00000358367SRSF7chr2

38973286

-HNRNPLLchr2

38829742

-
intron-3CDSENST00000446327ENST00000378915SRSF7chr2

38973286

-HNRNPLLchr2

38829742

-
intron-3CDSENST00000446327ENST00000409328SRSF7chr2

38973286

-HNRNPLLchr2

38829742

-
intron-3CDSENST00000446327ENST00000409636SRSF7chr2

38973286

-HNRNPLLchr2

38829742

-
intron-3CDSENST00000446327ENST00000410076SRSF7chr2

38973286

-HNRNPLLchr2

38829742

-
intron-3CDSENST00000446327ENST00000449105SRSF7chr2

38973286

-HNRNPLLchr2

38829742

-
intron-3CDSENST00000446327ENST00000608859SRSF7chr2

38973286

-HNRNPLLchr2

38829742

-
intron-5UTRENST00000446327ENST00000498516SRSF7chr2

38973286

-HNRNPLLchr2

38829742

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000313117SRSF7chr238973286-ENST00000409636HNRNPLLchr238829742-4707900522502816
ENST00000313117SRSF7chr238973286-ENST00000410076HNRNPLLchr238829742-2514900521716554
ENST00000409276SRSF7chr238973286-ENST00000409636HNRNPLLchr238829742-4562755152357780
ENST00000409276SRSF7chr238973286-ENST00000410076HNRNPLLchr238829742-2369755151571518

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000313117ENST00000409636SRSF7chr238973286-HNRNPLLchr238829742-0.0002985630.99970144
ENST00000313117ENST00000410076SRSF7chr238973286-HNRNPLLchr238829742-0.0027929760.997207
ENST00000409276ENST00000409636SRSF7chr238973286-HNRNPLLchr238829742-0.0002767990.99972314
ENST00000409276ENST00000410076SRSF7chr238973286-HNRNPLLchr238829742-0.0034117040.99658835

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Fusion Genomic Features for SRSF7-HNRNPLL


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for SRSF7-HNRNPLL


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr2:38973286/chr2:38829742)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
.HNRNPLL

Q8WVV9

FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: RNA-binding protein that functions as regulator of alternative splicing for multiple target mRNAs, including PTPRC/CD45 and STAT5A. Required for alternative splicing of PTPRC. {ECO:0000269|PubMed:18669861}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneSRSF7chr2:38973286chr2:38829742ENST00000313117-7811_84220239.0DomainRRM
HgeneSRSF7chr2:38973286chr2:38829742ENST00000313117-78153_160220239.0RepeatNote=1
HgeneSRSF7chr2:38973286chr2:38829742ENST00000313117-78161_168220239.0RepeatNote=2
HgeneSRSF7chr2:38973286chr2:38829742ENST00000313117-78169_176220239.0RepeatNote=3
HgeneSRSF7chr2:38973286chr2:38829742ENST00000313117-78177_184220239.0RepeatNote=4
HgeneSRSF7chr2:38973286chr2:38829742ENST00000313117-78211_218220239.0RepeatNote=5%3B approximate
HgeneSRSF7chr2:38973286chr2:38829742ENST00000313117-78104_120220239.0Zinc fingerCCHC-type
TgeneHNRNPLLchr2:38973286chr2:38829742ENST000004096360142_73538.0Compositional biasNote=Poly-Ser
TgeneHNRNPLLchr2:38973286chr2:38829742ENST0000040963601449_573538.0Compositional biasNote=Poly-Gly
TgeneHNRNPLLchr2:38973286chr2:38829742ENST00000410076072_73276.0Compositional biasNote=Poly-Ser
TgeneHNRNPLLchr2:38973286chr2:38829742ENST000004100760749_573276.0Compositional biasNote=Poly-Gly
TgeneHNRNPLLchr2:38973286chr2:38829742ENST00000409636014166_2443538.0DomainRRM 2
TgeneHNRNPLLchr2:38973286chr2:38829742ENST00000409636014335_4093538.0DomainRRM 3
TgeneHNRNPLLchr2:38973286chr2:38829742ENST0000040963601476_1503538.0DomainRRM 1
TgeneHNRNPLLchr2:38973286chr2:38829742ENST0000041007607166_2443276.0DomainRRM 2
TgeneHNRNPLLchr2:38973286chr2:38829742ENST0000041007607335_4093276.0DomainRRM 3
TgeneHNRNPLLchr2:38973286chr2:38829742ENST000004100760776_1503276.0DomainRRM 1

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneSRSF7chr2:38973286chr2:38829742ENST00000313117-78121_238220239.0Compositional biasNote=Arg/Ser-rich (RS domain)
HgeneSRSF7chr2:38973286chr2:38829742ENST00000446327-17121_2380227.0Compositional biasNote=Arg/Ser-rich (RS domain)
HgeneSRSF7chr2:38973286chr2:38829742ENST00000446327-1711_840227.0DomainRRM
HgeneSRSF7chr2:38973286chr2:38829742ENST00000313117-78153_226220239.0RegionNote=6 X 8 AA repeats of R-R-S-R-S-X-S-X
HgeneSRSF7chr2:38973286chr2:38829742ENST00000446327-17153_2260227.0RegionNote=6 X 8 AA repeats of R-R-S-R-S-X-S-X
HgeneSRSF7chr2:38973286chr2:38829742ENST00000313117-78219_226220239.0RepeatNote=6%3B approximate
HgeneSRSF7chr2:38973286chr2:38829742ENST00000446327-17153_1600227.0RepeatNote=1
HgeneSRSF7chr2:38973286chr2:38829742ENST00000446327-17161_1680227.0RepeatNote=2
HgeneSRSF7chr2:38973286chr2:38829742ENST00000446327-17169_1760227.0RepeatNote=3
HgeneSRSF7chr2:38973286chr2:38829742ENST00000446327-17177_1840227.0RepeatNote=4
HgeneSRSF7chr2:38973286chr2:38829742ENST00000446327-17211_2180227.0RepeatNote=5%3B approximate
HgeneSRSF7chr2:38973286chr2:38829742ENST00000446327-17219_2260227.0RepeatNote=6%3B approximate
HgeneSRSF7chr2:38973286chr2:38829742ENST00000446327-17104_1200227.0Zinc fingerCCHC-type


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Fusion Gene Sequence for SRSF7-HNRNPLL


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>86647_86647_1_SRSF7-HNRNPLL_SRSF7_chr2_38973286_ENST00000313117_HNRNPLL_chr2_38829742_ENST00000409636_length(transcript)=4707nt_BP=900nt
AGTCTCTTCAGTTCCTTCCGCGTCGTTTCTTGGCTGTTTCCGCCCAGCTCCTTTGTGCCGCGCAGAACAACGAGATGACGCATGCGCAAA
GCGCAGCGGCCGCATATATAAACGCGAACCCGGGCTCTTCCTCGTAGTGCCGCCGGGACTCTTGGCGGGTGAAGGTGTGTGTCAGCTTTT
GCGTCACTCGAGCCCTGGGCGCTGCTTGCTAAAGAGCCGAGCACGCGGGTCTGTCATCATGTCGCGTTACGGGCGGTACGGAGGAGAAAC
CAAGGTGTATGTTGGTAACCTGGGAACTGGCGCTGGCAAAGGAGAGTTAGAAAGGGCTTTCAGTTATTATGGTCCTTTAAGAACTGTATG
GATTGCGAGAAATCCTCCAGGATTTGCCTTTGTGGAATTCGAAGATCCTAGAGATGCAGAAGATGCAGTACGAGGACTGGATGGAAAGGT
GATTTGTGGCTCCCGAGTGAGGGTTGAACTATCGACAGGCATGCCTCGGAGATCACGTTTTGATAGACCACCTGCCCGACGTCCCTTTGA
TCCAAATGATAGATGCTATGAGTGTGGCGAAAAGGGACATTATGCTTATGATTGTCATCGTTACAGCCGGCGAAGAAGAAGCAGGTCACG
GTCTAGATCACATTCTCGATCCAGAGGAAGGCGATACTCTCGCTCACGCAGCAGGAGCAGGGGACGAAGGTCAAGGTCAGCATCTCCTCG
ACGATCAAGATCTATCTCTCTTCGTAGATCAAGATCAGCTTCACTCAGAAGATCTAGGTCTGGTTCTATAAAAGGATCGAGGTATTTCCA
ATCCCCGTCGAGGTCAAGATCAAGATCCAGGTCTATTTCACGACCAAGAAGCAGCCGATCAAAGTCCAGATCTCCATCTCCAAAAAGAAG
GGAGACGTACGAGGAGGACCGGGAGTACGAGAGCCAGGCCAAGCGTCTCAAGACCGAGGAGGGGGAGATCGACTACTCGGCCGAGGAAGG
CGAGAACCGCCGGGAAGCGACGCCCCGGGGCGGGGGCGATGGCGGCGGCGGCGGCCGGAGCTTCTCTCAGCCGGAGGCAGGTGGAAGTCA
TCATAAAGTTTCTGTTTCACCCGTCGTCCATGTTCGAGGACTCTGTGAATCTGTGGTGGAAGCAGACCTCGTGGAAGCGCTGGAAAAATT
TGGGACAATATGCTATGTGATGATGATGCCATTTAAACGACAGGCTCTAGTGGAATTTGAAAACATAGATAGTGCCAAAGAATGTGTGAC
ATTTGCTGCAGATGAACCCGTGTACATTGCTGGTCAACAGGCTTTTTTCAACTATTCTACAAGCAAAAGGATCACTCGGCCAGGAAATAC
TGATGATCCATCAGGAGGCAACAAAGTTCTTCTGCTCTCAATTCAGAATCCGCTTTATCCAATTACAGTGGATGTTTTATATACTGTATG
CAACCCTGTTGGCAAAGTGCAACGTATTGTTATATTCAAGAGAAATGGGATACAAGCAATGGTTGAGTTTGAATCAGTCCTTTGTGCCCA
GAAAGCTAAAGCAGCACTCAATGGAGCTGATATATATGCTGGATGTTGCACACTAAAAATTGAATATGCACGGCCAACTCGTCTAAATGT
TATTAGGAATGACAATGACAGTTGGGACTACACTAAACCATATTTGGGAAGACGAGATAGAGGAAAGGGTCGCCAGAGACAAGCCATTTT
GGGAGAACACCCTTCTTCGTTTAGACATGATGGCTATGGATCCCATGGTCCATTATTGCCTTTACCAAGTCGTTACAGAATGGGCTCTCG
AGATACACCTGAACTTGTTGCTTATCCATTACCACAGGCTTCTTCCTCTTACATGCATGGAGGAAATCCCTCTGGTTCAGTTGTAATGGT
TAGTGGATTACATCAACTAAAAATGAATTGTTCAAGAGTCTTCAACCTGTTCTGCTTATATGGAAATATTGAGAAGGTAAAATTTATGAA
GACCATTCCTGGTACAGCACTGGTAGAAATGGGTGATGAGTATGCTGTAGAAAGAGCTGTCACACACCTTAATAATGTCAAATTATTTGG
GAAAAGACTTAATGTTTGCGTGTCTAAACAACATTCAGTTGTTCCAAGTCAAATATTTGAGCTGGAGGATGGTACCAGCAGCTACAAAGA
TTTTGCAATGAGCAAAAATAATCGCTTTACAAGTGCTGGCCAAGCATCTAAGAATATAATCCAGCCACCCTCCTGTGTTTTGCATTATTA
TAATGTTCCATTGTGTGTCACAGAAGAGACCTTCACAAAGTTGTGTAATGACCATGAAGTTCTTACATTCATCAAATATAAAGTGTTTGA
TGCAAAACCTTCAGCCAAAACACTTTCTGGGCTATTAGAATGGGAGTGCAAAACTGATGCAGTAGAAGCCCTTACGGCACTGAATCACTA
TCAGATAAGAGTGCCGAATGGTTCCAATCCCTATACATTGAAGCTTTGCTTTTCTACATCATCCCATTTATAAGAAGAGAAGAGCATGTT
AGAATTTATGTTCACCTTTATTACAATTTCAAAGCTACACTTCATTAAAAAAAAATCTAAAATGGTTGATCTCATGTTGCCTTGCTTACT
TTAAGATCCTGTTCTGTAATAAACATATTTTGCCTTGAGTAAATTTGTTGTAAGCTTAAATATTGAATTGTTTTCATTTTAAGATAGAAT
ATCATAATGTAGACTATCTACAGCTTCATTGTAGATTATACAGATATATGATTTCTAACCTTATTACTGGAATTTTTCTTCCACAGTAAA
AATATATTTGCATTCTTAATGCTAATTATCTGCAAGTATTTTTTCATTGTGTAAGAGATTAATGCAGGTGAAAGTATTGCATTTTAATAT
AGAATTCCTATTATATGTTTAGATGTTTAAGTATGTTGCAGTTACTCATATTAAACATAACTTGTATATTTATTATTTTAATGAAGTTTG
AGAATAACGTTACATATGTTGAATTTTAAGTACTACAGATTTAACTGATTTTATATTTCTGAAAGGCTAACAGACATGGATACACGTGTA
CAGTATGCATTCAAACTTATTTAAATTGGTGTATTTTTTTTTAAGTCACTGTCCATTTGTATTGACATGCCTCTGTTTCTAGTCCAGTTT
GGAGATTTTATAAAGTTATAACAATGAGTTAATGTGTTCATTTTCATTTGTTGCATGTGACTTAAATACAGCTAGTATTTGGCATTGAGA
TTTTAATAGAGGTTATAATTAACAGTTCCTCTTATAGATAATAATCTGGGATCCATGGGTGGGCTTCAGAGAATCTGTGTACCCCCTAAA
ATTGTATGTAGAATTTTGGATATTTACATTTTTATTTTTTAACTCTTGGATCCATCAGTAATATGTATTTTTCTATATGGTACAAGATTT
AAGGATCTAATTTTATTTTTATTCCAAACAGATAGCTATTTGTCTCAATACCATTTATTAAACATTCTTTCTCCCACTGGATCTGTTTTT
TTTTTCTTTTTAAGATAATAGATTTTATACATAGGCAAGTAAGATTTAAGGACCAAACATGGTATTAAGAGACTATAGCACGATTGTTAC
CAAGTTCACAGCTTTTTTACAATAGAAAAACTGATGTGGCCATTTTGTTTTCATCTTTAAAAGAAGGGAGAATATGTGTCATCTACCTAG
AATAACTGATATCAGTAGTTGACAATATCAGTTTTGTAATCCTGACACTTTTAAACAAATTTGTAAATGAAAGTTCCATTTAGATCTTTT
GTAAAGACTTTATTTTAAATTTTAATATAAAAAATCCTTTTAGAAATAAGGCAGGCATTTACAATTTTAGAGCTGTTTAATAGGAAGTTT
AGATGGAAACTAAACACACATTAACATTTATTTCCCCTCATTTTGATGGCAGTGGACCAGCATTTAGCCCTCTAAAGATAAAGAAAAAAT
TAAATTTAATCTAGAAGTATTTTAGACCCTTATCACAGAACCCAGTAAGTTATGCCAAGGGTAACTGTGTGAACTGTGTTCGATACTGGG
CTATGTATGTTTCTTATTCATTGCCAATTTAATACCTAAGTTTATCTAACTTTACAATAAAGCTTTTTTTCCCCTATAAATACTTTTCTA
CCTCTTTTGAAAAATTGAAATACCTTAATTTTGGTTTATGTAATAGTTGTCTACGTTCCTTCCTCCTCTGAAAATTAATGTGGGTTGTCA
GAATTACAGACTTTTTAATGCCTAAGATTTTAAGAAATAAACCTGTAGGTGTTGGCAGGACTTATTTCATTTAGATTTTAATTAGTTTAG
ATGTGTAGAAATGATTTTTATCTGTAAGGCTCTCTCTCCACCAAAATAAGTGAATTGTTTGGGAGTAAACTAGTTGGTAAGTTGGGCCTT
GCTGATAGATTTATACACTGGTGTGTAAGCCCTATACTGCTGCTGTCACTAATGTTTTTGATAGTTTACTTAGGCATGACTGCTGTTAAT
GAAGTTTGCTTTGTGAATACTCTCTCTTTCCTTAGCCTTGGCAACATTCTTCTCTGTGCTATCTTTATGCTTTTAGAAGAACTAGAAAAA
GCAGATTTAAGAACTGTAAAGAAATAATACTAGCTTTGAGTTTTTAAAAAAAATATTGAAATCCCATCTCTGTATCCAAATCCTACTACA

>86647_86647_1_SRSF7-HNRNPLL_SRSF7_chr2_38973286_ENST00000313117_HNRNPLL_chr2_38829742_ENST00000409636_length(amino acids)=816AA_BP=1
MCRAEQRDDACAKRSGRIYKREPGLFLVVPPGLLAGEGVCQLLRHSSPGRCLLKSRARGSVIMSRYGRYGGETKVYVGNLGTGAGKGELE
RAFSYYGPLRTVWIARNPPGFAFVEFEDPRDAEDAVRGLDGKVICGSRVRVELSTGMPRRSRFDRPPARRPFDPNDRCYECGEKGHYAYD
CHRYSRRRRSRSRSRSHSRSRGRRYSRSRSRSRGRRSRSASPRRSRSISLRRSRSASLRRSRSGSIKGSRYFQSPSRSRSRSRSISRPRS
SRSKSRSPSPKRRETYEEDREYESQAKRLKTEEGEIDYSAEEGENRREATPRGGGDGGGGGRSFSQPEAGGSHHKVSVSPVVHVRGLCES
VVEADLVEALEKFGTICYVMMMPFKRQALVEFENIDSAKECVTFAADEPVYIAGQQAFFNYSTSKRITRPGNTDDPSGGNKVLLLSIQNP
LYPITVDVLYTVCNPVGKVQRIVIFKRNGIQAMVEFESVLCAQKAKAALNGADIYAGCCTLKIEYARPTRLNVIRNDNDSWDYTKPYLGR
RDRGKGRQRQAILGEHPSSFRHDGYGSHGPLLPLPSRYRMGSRDTPELVAYPLPQASSSYMHGGNPSGSVVMVSGLHQLKMNCSRVFNLF
CLYGNIEKVKFMKTIPGTALVEMGDEYAVERAVTHLNNVKLFGKRLNVCVSKQHSVVPSQIFELEDGTSSYKDFAMSKNNRFTSAGQASK
NIIQPPSCVLHYYNVPLCVTEETFTKLCNDHEVLTFIKYKVFDAKPSAKTLSGLLEWECKTDAVEALTALNHYQIRVPNGSNPYTLKLCF

--------------------------------------------------------------
>86647_86647_2_SRSF7-HNRNPLL_SRSF7_chr2_38973286_ENST00000313117_HNRNPLL_chr2_38829742_ENST00000410076_length(transcript)=2514nt_BP=900nt
AGTCTCTTCAGTTCCTTCCGCGTCGTTTCTTGGCTGTTTCCGCCCAGCTCCTTTGTGCCGCGCAGAACAACGAGATGACGCATGCGCAAA
GCGCAGCGGCCGCATATATAAACGCGAACCCGGGCTCTTCCTCGTAGTGCCGCCGGGACTCTTGGCGGGTGAAGGTGTGTGTCAGCTTTT
GCGTCACTCGAGCCCTGGGCGCTGCTTGCTAAAGAGCCGAGCACGCGGGTCTGTCATCATGTCGCGTTACGGGCGGTACGGAGGAGAAAC
CAAGGTGTATGTTGGTAACCTGGGAACTGGCGCTGGCAAAGGAGAGTTAGAAAGGGCTTTCAGTTATTATGGTCCTTTAAGAACTGTATG
GATTGCGAGAAATCCTCCAGGATTTGCCTTTGTGGAATTCGAAGATCCTAGAGATGCAGAAGATGCAGTACGAGGACTGGATGGAAAGGT
GATTTGTGGCTCCCGAGTGAGGGTTGAACTATCGACAGGCATGCCTCGGAGATCACGTTTTGATAGACCACCTGCCCGACGTCCCTTTGA
TCCAAATGATAGATGCTATGAGTGTGGCGAAAAGGGACATTATGCTTATGATTGTCATCGTTACAGCCGGCGAAGAAGAAGCAGGTCACG
GTCTAGATCACATTCTCGATCCAGAGGAAGGCGATACTCTCGCTCACGCAGCAGGAGCAGGGGACGAAGGTCAAGGTCAGCATCTCCTCG
ACGATCAAGATCTATCTCTCTTCGTAGATCAAGATCAGCTTCACTCAGAAGATCTAGGTCTGGTTCTATAAAAGGATCGAGGTATTTCCA
ATCCCCGTCGAGGTCAAGATCAAGATCCAGGTCTATTTCACGACCAAGAAGCAGCCGATCAAAGTCCAGATCTCCATCTCCAAAAAGAAG
GGAGACGTACGAGGAGGACCGGGAGTACGAGAGCCAGGCCAAGCGTCTCAAGACCGAGGAGGGGGAGATCGACTACTCGGCCGAGGAAGG
CGAGAACCGCCGGGAAGCGACGCCCCGGGGCGGGGGCGATGGCGGCGGCGGCGGCCGGAGCTTCTCTCAGCCGGAGGCAGGTGGAAGTCA
TCATAAAGTTTCTGTTTCACCCGTCGTCCATGTTCGAGGACTCTGTGAATCTGTGGTGGAAGCAGACCTCGTGGAAGCGCTGGAAAAATT
TGGGACAATATGCTATGTGATGATGATGCCATTTAAACGACAGGCTCTAGTGGAATTTGAAAACATAGATAGTGCCAAAGAATGTGTGAC
ATTTGCTGCAGATGAACCCGTGTACATTGCTGGTCAACAGGCTTTTTTCAACTATTCTACAAGCAAAAGGATCACTCGGCCAGGAAATAC
TGATGATCCATCAGGAGGCAACAAAGTTCTTCTGCTCTCAATTCAGAATCCGCTTTATCCAATTACAGTGGATGTTTTATATACTGTATG
CAACCCTGTTGGCAAAGTGCAACGTATTGTTATATTCAAGAGAAATGGGATACAAGCAATGGTTGAGTTTGAATCAGTCCTTTGTGCCCA
GAAAGCTAAAGCAGCACTCAATGGAGCTGATATATATGCTGGATGTTGCACACTAAAAATTGAATATGCACGGCCAACTCGTCTAAATGT
TATTAGGAATGACAATGACAGTTGGGACTACACTAAACCATATTTGGGAAGACGAGGTAGGTATTTTATACATTTTAGAATGTACTTGAT
CTGCTGACAAATTTTTATATGCAGTTAGATTCTTTTTTCCTGAGATGAGCTAGTTAATTCAAATGAAAACCTTGTTGATGAATGCTTTTG
TTGCAAAAGGCCATGTAATGCTGGAAAATAACCTTGAACATTAGTGCCCCCTACTGGTATGTACTGAGCTATTTATATTTAGTTCAACAA
GGAGCCCACACATTCAGGCACGCCCGCAGTTCAAGGACTTGCATTTCTCCAAGCAGCTCTCTCTCTTTGGAGGAGAGGAAACTGATTCAG
AATATTCCTTACAAACTGCAAACTTGCACACTGCTTCTCTATGGAAAGGACTTTCCCCCAAGCTGGACGAGGCATTAAGAAGGATAGAGG
ACTCCAGCAGGCTGACTCTACACTTCATCATGCACAACATCGGCATCAGCAAAAAGCCCTCTGAAAAACTCAGACTCGCAATTCACCTTG
ACTGCATACTGCATGCACCATCACCCCAAGTTTTTAAAGGAGGACACTTAACAGTACTTCAGAATTGCATGGGATGAACACCATGATAGA
CTGTGCCCATTTATACAAGTTGTATGTATATATTGGTCTGATTTCCCTTAAGGTTTCAGTTGTAGAATTTAAGACTTTCCACTAACGGAA
ACTAGACTTCATCTGCAATGTTGTAAATCTTAATGCCCATTACTGTGACTGTGTGCAGCTTAGATTCAAATTGTTAATTGGCAAATAACC

>86647_86647_2_SRSF7-HNRNPLL_SRSF7_chr2_38973286_ENST00000313117_HNRNPLL_chr2_38829742_ENST00000410076_length(amino acids)=554AA_BP=1
MCRAEQRDDACAKRSGRIYKREPGLFLVVPPGLLAGEGVCQLLRHSSPGRCLLKSRARGSVIMSRYGRYGGETKVYVGNLGTGAGKGELE
RAFSYYGPLRTVWIARNPPGFAFVEFEDPRDAEDAVRGLDGKVICGSRVRVELSTGMPRRSRFDRPPARRPFDPNDRCYECGEKGHYAYD
CHRYSRRRRSRSRSRSHSRSRGRRYSRSRSRSRGRRSRSASPRRSRSISLRRSRSASLRRSRSGSIKGSRYFQSPSRSRSRSRSISRPRS
SRSKSRSPSPKRRETYEEDREYESQAKRLKTEEGEIDYSAEEGENRREATPRGGGDGGGGGRSFSQPEAGGSHHKVSVSPVVHVRGLCES
VVEADLVEALEKFGTICYVMMMPFKRQALVEFENIDSAKECVTFAADEPVYIAGQQAFFNYSTSKRITRPGNTDDPSGGNKVLLLSIQNP
LYPITVDVLYTVCNPVGKVQRIVIFKRNGIQAMVEFESVLCAQKAKAALNGADIYAGCCTLKIEYARPTRLNVIRNDNDSWDYTKPYLGR

--------------------------------------------------------------
>86647_86647_3_SRSF7-HNRNPLL_SRSF7_chr2_38973286_ENST00000409276_HNRNPLL_chr2_38829742_ENST00000409636_length(transcript)=4562nt_BP=755nt
GTGCCGCCGGGACTCTTGGCGGGTGAAGGTGTGTGTCAGCTTTTGCGTCACTCGAGCCCTGGGCGCTGCTTGCTAAAGAGCCGAGCACGC
GGGTCTGTCATCATGTCGCGTTACGGGCGGTACGGAGGAGAAACCAAGGTGTATGTTGGTAACCTGGGAACTGGCGCTGGCAAAGGAGAG
TTAGAAAGGGCTTTCAGTTATTATGGTCCTTTAAGAACTGTATGGATTGCGAGAAATCCTCCAGGATTTGCCTTTGTGGAATTCGAAGAT
CCTAGAGATGCAGAAGATGCAGTACGAGGACTGGATGGAAAGGTGATTTGTGGCTCCCGAGTGAGGGTTGAACTATCGACAGGCATGCCT
CGGAGATCACGTTTTGATAGACCACCTGCCCGACGTCCCTTTGATCCAAATGATAGATGCTATGAGTGTGGCGAAAAGGGACATTATGCT
TATGATTGTCATCGTTACAGCCGGCGAAGAAGAAGCAGGTCACGGTCTAGATCACATTCTCGATCCAGAGGAAGGCGATACTCTCGCTCA
CGCAGCAGGAGCAGGGGACGAAGGTCAAGGTCAGCATCTCCTCGACGATCAAGATCTATCTCTCTTCGTAGATCAAGATCAGCTTCACTC
AGAAGATCTAGGTCTGGTTCTATAAAAGGATCGAGATCCCCGTCGAGGTCAAGATCAAGATCCAGGTCTATTTCACGACCAAGAAGCAGC
CGATCAAAGTCCAGATCTCCATCTCCAAAAAGAAGGGAGACGTACGAGGAGGACCGGGAGTACGAGAGCCAGGCCAAGCGTCTCAAGACC
GAGGAGGGGGAGATCGACTACTCGGCCGAGGAAGGCGAGAACCGCCGGGAAGCGACGCCCCGGGGCGGGGGCGATGGCGGCGGCGGCGGC
CGGAGCTTCTCTCAGCCGGAGGCAGGTGGAAGTCATCATAAAGTTTCTGTTTCACCCGTCGTCCATGTTCGAGGACTCTGTGAATCTGTG
GTGGAAGCAGACCTCGTGGAAGCGCTGGAAAAATTTGGGACAATATGCTATGTGATGATGATGCCATTTAAACGACAGGCTCTAGTGGAA
TTTGAAAACATAGATAGTGCCAAAGAATGTGTGACATTTGCTGCAGATGAACCCGTGTACATTGCTGGTCAACAGGCTTTTTTCAACTAT
TCTACAAGCAAAAGGATCACTCGGCCAGGAAATACTGATGATCCATCAGGAGGCAACAAAGTTCTTCTGCTCTCAATTCAGAATCCGCTT
TATCCAATTACAGTGGATGTTTTATATACTGTATGCAACCCTGTTGGCAAAGTGCAACGTATTGTTATATTCAAGAGAAATGGGATACAA
GCAATGGTTGAGTTTGAATCAGTCCTTTGTGCCCAGAAAGCTAAAGCAGCACTCAATGGAGCTGATATATATGCTGGATGTTGCACACTA
AAAATTGAATATGCACGGCCAACTCGTCTAAATGTTATTAGGAATGACAATGACAGTTGGGACTACACTAAACCATATTTGGGAAGACGA
GATAGAGGAAAGGGTCGCCAGAGACAAGCCATTTTGGGAGAACACCCTTCTTCGTTTAGACATGATGGCTATGGATCCCATGGTCCATTA
TTGCCTTTACCAAGTCGTTACAGAATGGGCTCTCGAGATACACCTGAACTTGTTGCTTATCCATTACCACAGGCTTCTTCCTCTTACATG
CATGGAGGAAATCCCTCTGGTTCAGTTGTAATGGTTAGTGGATTACATCAACTAAAAATGAATTGTTCAAGAGTCTTCAACCTGTTCTGC
TTATATGGAAATATTGAGAAGGTAAAATTTATGAAGACCATTCCTGGTACAGCACTGGTAGAAATGGGTGATGAGTATGCTGTAGAAAGA
GCTGTCACACACCTTAATAATGTCAAATTATTTGGGAAAAGACTTAATGTTTGCGTGTCTAAACAACATTCAGTTGTTCCAAGTCAAATA
TTTGAGCTGGAGGATGGTACCAGCAGCTACAAAGATTTTGCAATGAGCAAAAATAATCGCTTTACAAGTGCTGGCCAAGCATCTAAGAAT
ATAATCCAGCCACCCTCCTGTGTTTTGCATTATTATAATGTTCCATTGTGTGTCACAGAAGAGACCTTCACAAAGTTGTGTAATGACCAT
GAAGTTCTTACATTCATCAAATATAAAGTGTTTGATGCAAAACCTTCAGCCAAAACACTTTCTGGGCTATTAGAATGGGAGTGCAAAACT
GATGCAGTAGAAGCCCTTACGGCACTGAATCACTATCAGATAAGAGTGCCGAATGGTTCCAATCCCTATACATTGAAGCTTTGCTTTTCT
ACATCATCCCATTTATAAGAAGAGAAGAGCATGTTAGAATTTATGTTCACCTTTATTACAATTTCAAAGCTACACTTCATTAAAAAAAAA
TCTAAAATGGTTGATCTCATGTTGCCTTGCTTACTTTAAGATCCTGTTCTGTAATAAACATATTTTGCCTTGAGTAAATTTGTTGTAAGC
TTAAATATTGAATTGTTTTCATTTTAAGATAGAATATCATAATGTAGACTATCTACAGCTTCATTGTAGATTATACAGATATATGATTTC
TAACCTTATTACTGGAATTTTTCTTCCACAGTAAAAATATATTTGCATTCTTAATGCTAATTATCTGCAAGTATTTTTTCATTGTGTAAG
AGATTAATGCAGGTGAAAGTATTGCATTTTAATATAGAATTCCTATTATATGTTTAGATGTTTAAGTATGTTGCAGTTACTCATATTAAA
CATAACTTGTATATTTATTATTTTAATGAAGTTTGAGAATAACGTTACATATGTTGAATTTTAAGTACTACAGATTTAACTGATTTTATA
TTTCTGAAAGGCTAACAGACATGGATACACGTGTACAGTATGCATTCAAACTTATTTAAATTGGTGTATTTTTTTTTAAGTCACTGTCCA
TTTGTATTGACATGCCTCTGTTTCTAGTCCAGTTTGGAGATTTTATAAAGTTATAACAATGAGTTAATGTGTTCATTTTCATTTGTTGCA
TGTGACTTAAATACAGCTAGTATTTGGCATTGAGATTTTAATAGAGGTTATAATTAACAGTTCCTCTTATAGATAATAATCTGGGATCCA
TGGGTGGGCTTCAGAGAATCTGTGTACCCCCTAAAATTGTATGTAGAATTTTGGATATTTACATTTTTATTTTTTAACTCTTGGATCCAT
CAGTAATATGTATTTTTCTATATGGTACAAGATTTAAGGATCTAATTTTATTTTTATTCCAAACAGATAGCTATTTGTCTCAATACCATT
TATTAAACATTCTTTCTCCCACTGGATCTGTTTTTTTTTTCTTTTTAAGATAATAGATTTTATACATAGGCAAGTAAGATTTAAGGACCA
AACATGGTATTAAGAGACTATAGCACGATTGTTACCAAGTTCACAGCTTTTTTACAATAGAAAAACTGATGTGGCCATTTTGTTTTCATC
TTTAAAAGAAGGGAGAATATGTGTCATCTACCTAGAATAACTGATATCAGTAGTTGACAATATCAGTTTTGTAATCCTGACACTTTTAAA
CAAATTTGTAAATGAAAGTTCCATTTAGATCTTTTGTAAAGACTTTATTTTAAATTTTAATATAAAAAATCCTTTTAGAAATAAGGCAGG
CATTTACAATTTTAGAGCTGTTTAATAGGAAGTTTAGATGGAAACTAAACACACATTAACATTTATTTCCCCTCATTTTGATGGCAGTGG
ACCAGCATTTAGCCCTCTAAAGATAAAGAAAAAATTAAATTTAATCTAGAAGTATTTTAGACCCTTATCACAGAACCCAGTAAGTTATGC
CAAGGGTAACTGTGTGAACTGTGTTCGATACTGGGCTATGTATGTTTCTTATTCATTGCCAATTTAATACCTAAGTTTATCTAACTTTAC
AATAAAGCTTTTTTTCCCCTATAAATACTTTTCTACCTCTTTTGAAAAATTGAAATACCTTAATTTTGGTTTATGTAATAGTTGTCTACG
TTCCTTCCTCCTCTGAAAATTAATGTGGGTTGTCAGAATTACAGACTTTTTAATGCCTAAGATTTTAAGAAATAAACCTGTAGGTGTTGG
CAGGACTTATTTCATTTAGATTTTAATTAGTTTAGATGTGTAGAAATGATTTTTATCTGTAAGGCTCTCTCTCCACCAAAATAAGTGAAT
TGTTTGGGAGTAAACTAGTTGGTAAGTTGGGCCTTGCTGATAGATTTATACACTGGTGTGTAAGCCCTATACTGCTGCTGTCACTAATGT
TTTTGATAGTTTACTTAGGCATGACTGCTGTTAATGAAGTTTGCTTTGTGAATACTCTCTCTTTCCTTAGCCTTGGCAACATTCTTCTCT
GTGCTATCTTTATGCTTTTAGAAGAACTAGAAAAAGCAGATTTAAGAACTGTAAAGAAATAATACTAGCTTTGAGTTTTTAAAAAAAATA

>86647_86647_3_SRSF7-HNRNPLL_SRSF7_chr2_38973286_ENST00000409276_HNRNPLL_chr2_38829742_ENST00000409636_length(amino acids)=780AA_BP=149
MAGEGVCQLLRHSSPGRCLLKSRARGSVIMSRYGRYGGETKVYVGNLGTGAGKGELERAFSYYGPLRTVWIARNPPGFAFVEFEDPRDAE
DAVRGLDGKVICGSRVRVELSTGMPRRSRFDRPPARRPFDPNDRCYECGEKGHYAYDCHRYSRRRRSRSRSRSHSRSRGRRYSRSRSRSR
GRRSRSASPRRSRSISLRRSRSASLRRSRSGSIKGSRSPSRSRSRSRSISRPRSSRSKSRSPSPKRRETYEEDREYESQAKRLKTEEGEI
DYSAEEGENRREATPRGGGDGGGGGRSFSQPEAGGSHHKVSVSPVVHVRGLCESVVEADLVEALEKFGTICYVMMMPFKRQALVEFENID
SAKECVTFAADEPVYIAGQQAFFNYSTSKRITRPGNTDDPSGGNKVLLLSIQNPLYPITVDVLYTVCNPVGKVQRIVIFKRNGIQAMVEF
ESVLCAQKAKAALNGADIYAGCCTLKIEYARPTRLNVIRNDNDSWDYTKPYLGRRDRGKGRQRQAILGEHPSSFRHDGYGSHGPLLPLPS
RYRMGSRDTPELVAYPLPQASSSYMHGGNPSGSVVMVSGLHQLKMNCSRVFNLFCLYGNIEKVKFMKTIPGTALVEMGDEYAVERAVTHL
NNVKLFGKRLNVCVSKQHSVVPSQIFELEDGTSSYKDFAMSKNNRFTSAGQASKNIIQPPSCVLHYYNVPLCVTEETFTKLCNDHEVLTF

--------------------------------------------------------------
>86647_86647_4_SRSF7-HNRNPLL_SRSF7_chr2_38973286_ENST00000409276_HNRNPLL_chr2_38829742_ENST00000410076_length(transcript)=2369nt_BP=755nt
GTGCCGCCGGGACTCTTGGCGGGTGAAGGTGTGTGTCAGCTTTTGCGTCACTCGAGCCCTGGGCGCTGCTTGCTAAAGAGCCGAGCACGC
GGGTCTGTCATCATGTCGCGTTACGGGCGGTACGGAGGAGAAACCAAGGTGTATGTTGGTAACCTGGGAACTGGCGCTGGCAAAGGAGAG
TTAGAAAGGGCTTTCAGTTATTATGGTCCTTTAAGAACTGTATGGATTGCGAGAAATCCTCCAGGATTTGCCTTTGTGGAATTCGAAGAT
CCTAGAGATGCAGAAGATGCAGTACGAGGACTGGATGGAAAGGTGATTTGTGGCTCCCGAGTGAGGGTTGAACTATCGACAGGCATGCCT
CGGAGATCACGTTTTGATAGACCACCTGCCCGACGTCCCTTTGATCCAAATGATAGATGCTATGAGTGTGGCGAAAAGGGACATTATGCT
TATGATTGTCATCGTTACAGCCGGCGAAGAAGAAGCAGGTCACGGTCTAGATCACATTCTCGATCCAGAGGAAGGCGATACTCTCGCTCA
CGCAGCAGGAGCAGGGGACGAAGGTCAAGGTCAGCATCTCCTCGACGATCAAGATCTATCTCTCTTCGTAGATCAAGATCAGCTTCACTC
AGAAGATCTAGGTCTGGTTCTATAAAAGGATCGAGATCCCCGTCGAGGTCAAGATCAAGATCCAGGTCTATTTCACGACCAAGAAGCAGC
CGATCAAAGTCCAGATCTCCATCTCCAAAAAGAAGGGAGACGTACGAGGAGGACCGGGAGTACGAGAGCCAGGCCAAGCGTCTCAAGACC
GAGGAGGGGGAGATCGACTACTCGGCCGAGGAAGGCGAGAACCGCCGGGAAGCGACGCCCCGGGGCGGGGGCGATGGCGGCGGCGGCGGC
CGGAGCTTCTCTCAGCCGGAGGCAGGTGGAAGTCATCATAAAGTTTCTGTTTCACCCGTCGTCCATGTTCGAGGACTCTGTGAATCTGTG
GTGGAAGCAGACCTCGTGGAAGCGCTGGAAAAATTTGGGACAATATGCTATGTGATGATGATGCCATTTAAACGACAGGCTCTAGTGGAA
TTTGAAAACATAGATAGTGCCAAAGAATGTGTGACATTTGCTGCAGATGAACCCGTGTACATTGCTGGTCAACAGGCTTTTTTCAACTAT
TCTACAAGCAAAAGGATCACTCGGCCAGGAAATACTGATGATCCATCAGGAGGCAACAAAGTTCTTCTGCTCTCAATTCAGAATCCGCTT
TATCCAATTACAGTGGATGTTTTATATACTGTATGCAACCCTGTTGGCAAAGTGCAACGTATTGTTATATTCAAGAGAAATGGGATACAA
GCAATGGTTGAGTTTGAATCAGTCCTTTGTGCCCAGAAAGCTAAAGCAGCACTCAATGGAGCTGATATATATGCTGGATGTTGCACACTA
AAAATTGAATATGCACGGCCAACTCGTCTAAATGTTATTAGGAATGACAATGACAGTTGGGACTACACTAAACCATATTTGGGAAGACGA
GGTAGGTATTTTATACATTTTAGAATGTACTTGATCTGCTGACAAATTTTTATATGCAGTTAGATTCTTTTTTCCTGAGATGAGCTAGTT
AATTCAAATGAAAACCTTGTTGATGAATGCTTTTGTTGCAAAAGGCCATGTAATGCTGGAAAATAACCTTGAACATTAGTGCCCCCTACT
GGTATGTACTGAGCTATTTATATTTAGTTCAACAAGGAGCCCACACATTCAGGCACGCCCGCAGTTCAAGGACTTGCATTTCTCCAAGCA
GCTCTCTCTCTTTGGAGGAGAGGAAACTGATTCAGAATATTCCTTACAAACTGCAAACTTGCACACTGCTTCTCTATGGAAAGGACTTTC
CCCCAAGCTGGACGAGGCATTAAGAAGGATAGAGGACTCCAGCAGGCTGACTCTACACTTCATCATGCACAACATCGGCATCAGCAAAAA
GCCCTCTGAAAAACTCAGACTCGCAATTCACCTTGACTGCATACTGCATGCACCATCACCCCAAGTTTTTAAAGGAGGACACTTAACAGT
ACTTCAGAATTGCATGGGATGAACACCATGATAGACTGTGCCCATTTATACAAGTTGTATGTATATATTGGTCTGATTTCCCTTAAGGTT
TCAGTTGTAGAATTTAAGACTTTCCACTAACGGAAACTAGACTTCATCTGCAATGTTGTAAATCTTAATGCCCATTACTGTGACTGTGTG
CAGCTTAGATTCAAATTGTTAATTGGCAAATAACCAGGACCAGTTTATTAACAGGTCTTGGGAATTGATAATGCTCAACCAATCCACACA

>86647_86647_4_SRSF7-HNRNPLL_SRSF7_chr2_38973286_ENST00000409276_HNRNPLL_chr2_38829742_ENST00000410076_length(amino acids)=518AA_BP=149
MAGEGVCQLLRHSSPGRCLLKSRARGSVIMSRYGRYGGETKVYVGNLGTGAGKGELERAFSYYGPLRTVWIARNPPGFAFVEFEDPRDAE
DAVRGLDGKVICGSRVRVELSTGMPRRSRFDRPPARRPFDPNDRCYECGEKGHYAYDCHRYSRRRRSRSRSRSHSRSRGRRYSRSRSRSR
GRRSRSASPRRSRSISLRRSRSASLRRSRSGSIKGSRSPSRSRSRSRSISRPRSSRSKSRSPSPKRRETYEEDREYESQAKRLKTEEGEI
DYSAEEGENRREATPRGGGDGGGGGRSFSQPEAGGSHHKVSVSPVVHVRGLCESVVEADLVEALEKFGTICYVMMMPFKRQALVEFENID
SAKECVTFAADEPVYIAGQQAFFNYSTSKRITRPGNTDDPSGGNKVLLLSIQNPLYPITVDVLYTVCNPVGKVQRIVIFKRNGIQAMVEF

--------------------------------------------------------------

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Fusion Gene PPI Analysis for SRSF7-HNRNPLL


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for SRSF7-HNRNPLL


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for SRSF7-HNRNPLL


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource