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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:STAMBP-AQP4 (FusionGDB2 ID:87129)

Fusion Gene Summary for STAMBP-AQP4

check button Fusion gene summary
Fusion gene informationFusion gene name: STAMBP-AQP4
Fusion gene ID: 87129
HgeneTgene
Gene symbol

STAMBP

AQP4

Gene ID

10617

361

Gene nameSTAM binding proteinaquaporin 4
SynonymsAMSH|MICCAPMIWC|WCH4
Cytomap

2p13.1

18q11.2

Type of geneprotein-codingprotein-coding
DescriptionSTAM-binding proteinassociated molecule with the SH3 domain of STAMendosome-associated ubiquitin isopeptidasetesticular secretory protein Li 54aquaporin-4aquaporin type4mercurial-insensitive water channel
Modification date2020031320200329
UniProtAcc.

P55087

Ensembl transtripts involved in fusion geneENST00000339566, ENST00000394070, 
ENST00000394073, ENST00000409707, 
ENST00000536064, ENST00000486458, 
ENST00000440832, ENST00000581374, 
ENST00000583022, ENST00000383168, 
Fusion gene scores* DoF score5 X 4 X 3=605 X 3 X 4=60
# samples 66
** MAII scorelog2(6/60*10)=0log2(6/60*10)=0
Context

PubMed: STAMBP [Title/Abstract] AND AQP4 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointSTAMBP(74058186)-AQP4(24442560), # samples:2
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
TgeneAQP4

GO:0006833

water transport

8601457|19383790

TgeneAQP4

GO:0051289

protein homotetramerization

19383790

TgeneAQP4

GO:0071346

cellular response to interferon-gamma

17645239


check buttonFusion gene breakpoints across STAMBP (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across AQP4 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4KIRCTCGA-CZ-4854-01ASTAMBPchr2

74058186

+AQP4chr18

24442560

-


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Fusion Gene ORF analysis for STAMBP-AQP4

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-5UTRENST00000339566ENST00000440832STAMBPchr2

74058186

+AQP4chr18

24442560

-
5CDS-5UTRENST00000339566ENST00000581374STAMBPchr2

74058186

+AQP4chr18

24442560

-
5CDS-5UTRENST00000394070ENST00000440832STAMBPchr2

74058186

+AQP4chr18

24442560

-
5CDS-5UTRENST00000394070ENST00000581374STAMBPchr2

74058186

+AQP4chr18

24442560

-
5CDS-5UTRENST00000394073ENST00000440832STAMBPchr2

74058186

+AQP4chr18

24442560

-
5CDS-5UTRENST00000394073ENST00000581374STAMBPchr2

74058186

+AQP4chr18

24442560

-
5CDS-5UTRENST00000409707ENST00000440832STAMBPchr2

74058186

+AQP4chr18

24442560

-
5CDS-5UTRENST00000409707ENST00000581374STAMBPchr2

74058186

+AQP4chr18

24442560

-
5CDS-5UTRENST00000536064ENST00000440832STAMBPchr2

74058186

+AQP4chr18

24442560

-
5CDS-5UTRENST00000536064ENST00000581374STAMBPchr2

74058186

+AQP4chr18

24442560

-
5CDS-intronENST00000339566ENST00000583022STAMBPchr2

74058186

+AQP4chr18

24442560

-
5CDS-intronENST00000394070ENST00000583022STAMBPchr2

74058186

+AQP4chr18

24442560

-
5CDS-intronENST00000394073ENST00000583022STAMBPchr2

74058186

+AQP4chr18

24442560

-
5CDS-intronENST00000409707ENST00000583022STAMBPchr2

74058186

+AQP4chr18

24442560

-
5CDS-intronENST00000536064ENST00000583022STAMBPchr2

74058186

+AQP4chr18

24442560

-
In-frameENST00000339566ENST00000383168STAMBPchr2

74058186

+AQP4chr18

24442560

-
In-frameENST00000394070ENST00000383168STAMBPchr2

74058186

+AQP4chr18

24442560

-
In-frameENST00000394073ENST00000383168STAMBPchr2

74058186

+AQP4chr18

24442560

-
In-frameENST00000409707ENST00000383168STAMBPchr2

74058186

+AQP4chr18

24442560

-
In-frameENST00000536064ENST00000383168STAMBPchr2

74058186

+AQP4chr18

24442560

-
intron-3CDSENST00000486458ENST00000383168STAMBPchr2

74058186

+AQP4chr18

24442560

-
intron-5UTRENST00000486458ENST00000440832STAMBPchr2

74058186

+AQP4chr18

24442560

-
intron-5UTRENST00000486458ENST00000581374STAMBPchr2

74058186

+AQP4chr18

24442560

-
intron-intronENST00000486458ENST00000583022STAMBPchr2

74058186

+AQP4chr18

24442560

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000339566STAMBPchr274058186+ENST00000383168AQP4chr1824442560-5366253411192383
ENST00000409707STAMBPchr274058186+ENST00000383168AQP4chr1824442560-5363250381189383
ENST00000394073STAMBPchr274058186+ENST00000383168AQP4chr1824442560-5505392451331428
ENST00000394070STAMBPchr274058186+ENST00000383168AQP4chr1824442560-58197062031645480
ENST00000536064STAMBPchr274058186+ENST00000383168AQP4chr1824442560-5474361141300428

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000339566ENST00000383168STAMBPchr274058186+AQP4chr1824442560-0.0001801970.9998198
ENST00000409707ENST00000383168STAMBPchr274058186+AQP4chr1824442560-0.0001807940.9998192
ENST00000394073ENST00000383168STAMBPchr274058186+AQP4chr1824442560-0.000177820.9998222
ENST00000394070ENST00000383168STAMBPchr274058186+AQP4chr1824442560-0.000188330.9998117
ENST00000536064ENST00000383168STAMBPchr274058186+AQP4chr1824442560-0.0001817760.99981827

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Fusion Genomic Features for STAMBP-AQP4


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for STAMBP-AQP4


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr2:74058186/chr18:24442560)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
.AQP4

P55087

FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Forms a water-specific channel (PubMed:7559426, PubMed:8601457, PubMed:19383790). Plays an important role in brain water homeostasis and in glymphatic solute transport. Required for a normal rate of water exchange across the blood brain interface. Required for normal levels of cerebrospinal fluid influx into the brain cortex and parenchyma along paravascular spaces that surround penetrating arteries, and for normal drainage of interstitial fluid along paravenous drainage pathways. Thereby, it is required for normal clearance of solutes from the brain interstitial fluid, including soluble beta-amyloid peptides derived from APP. Plays a redundant role in urinary water homeostasis and urinary concentrating ability (By similarity). {ECO:0000250|UniProtKB:P55088, ECO:0000269|PubMed:19383790, ECO:0000269|PubMed:7559426, ECO:0000269|PubMed:8601457}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneAQP4chr2:74058186chr18:24442560ENST0000038316805209_22210324.0IntramembraneDiscontinuously helical
TgeneAQP4chr2:74058186chr18:24442560ENST000003831680594_10110324.0IntramembraneDiscontinuously helical
TgeneAQP4chr2:74058186chr18:24442560ENST0000044083205209_2220302.0IntramembraneDiscontinuously helical
TgeneAQP4chr2:74058186chr18:24442560ENST000004408320594_1010302.0IntramembraneDiscontinuously helical
TgeneAQP4chr2:74058186chr18:24442560ENST0000058137404209_2220302.0IntramembraneDiscontinuously helical
TgeneAQP4chr2:74058186chr18:24442560ENST000005813740494_1010302.0IntramembraneDiscontinuously helical
TgeneAQP4chr2:74058186chr18:24442560ENST0000038316805213_21510324.0MotifNPA 2
TgeneAQP4chr2:74058186chr18:24442560ENST000003831680597_9910324.0MotifNPA 1
TgeneAQP4chr2:74058186chr18:24442560ENST0000044083205213_2150302.0MotifNPA 2
TgeneAQP4chr2:74058186chr18:24442560ENST000004408320597_990302.0MotifNPA 1
TgeneAQP4chr2:74058186chr18:24442560ENST0000058137404213_2150302.0MotifNPA 2
TgeneAQP4chr2:74058186chr18:24442560ENST000005813740497_990302.0MotifNPA 1
TgeneAQP4chr2:74058186chr18:24442560ENST0000038316805102_11510324.0Topological domainCytoplasmic
TgeneAQP4chr2:74058186chr18:24442560ENST0000038316805137_15510324.0Topological domainExtracellular
TgeneAQP4chr2:74058186chr18:24442560ENST0000038316805177_18410324.0Topological domainCytoplasmic
TgeneAQP4chr2:74058186chr18:24442560ENST0000038316805206_20810324.0Topological domainExtracellular
TgeneAQP4chr2:74058186chr18:24442560ENST0000038316805223_23110324.0Topological domainExtracellular
TgeneAQP4chr2:74058186chr18:24442560ENST0000038316805253_32310324.0Topological domainCytoplasmic
TgeneAQP4chr2:74058186chr18:24442560ENST000003831680558_6910324.0Topological domainExtracellular
TgeneAQP4chr2:74058186chr18:24442560ENST000003831680590_9310324.0Topological domainCytoplasmic
TgeneAQP4chr2:74058186chr18:24442560ENST0000044083205102_1150302.0Topological domainCytoplasmic
TgeneAQP4chr2:74058186chr18:24442560ENST0000044083205137_1550302.0Topological domainExtracellular
TgeneAQP4chr2:74058186chr18:24442560ENST0000044083205177_1840302.0Topological domainCytoplasmic
TgeneAQP4chr2:74058186chr18:24442560ENST00000440832051_360302.0Topological domainCytoplasmic
TgeneAQP4chr2:74058186chr18:24442560ENST0000044083205206_2080302.0Topological domainExtracellular
TgeneAQP4chr2:74058186chr18:24442560ENST0000044083205223_2310302.0Topological domainExtracellular
TgeneAQP4chr2:74058186chr18:24442560ENST0000044083205253_3230302.0Topological domainCytoplasmic
TgeneAQP4chr2:74058186chr18:24442560ENST000004408320558_690302.0Topological domainExtracellular
TgeneAQP4chr2:74058186chr18:24442560ENST000004408320590_930302.0Topological domainCytoplasmic
TgeneAQP4chr2:74058186chr18:24442560ENST0000058137404102_1150302.0Topological domainCytoplasmic
TgeneAQP4chr2:74058186chr18:24442560ENST0000058137404137_1550302.0Topological domainExtracellular
TgeneAQP4chr2:74058186chr18:24442560ENST0000058137404177_1840302.0Topological domainCytoplasmic
TgeneAQP4chr2:74058186chr18:24442560ENST00000581374041_360302.0Topological domainCytoplasmic
TgeneAQP4chr2:74058186chr18:24442560ENST0000058137404206_2080302.0Topological domainExtracellular
TgeneAQP4chr2:74058186chr18:24442560ENST0000058137404223_2310302.0Topological domainExtracellular
TgeneAQP4chr2:74058186chr18:24442560ENST0000058137404253_3230302.0Topological domainCytoplasmic
TgeneAQP4chr2:74058186chr18:24442560ENST000005813740458_690302.0Topological domainExtracellular
TgeneAQP4chr2:74058186chr18:24442560ENST000005813740490_930302.0Topological domainCytoplasmic
TgeneAQP4chr2:74058186chr18:24442560ENST0000038316805116_13610324.0TransmembraneHelical
TgeneAQP4chr2:74058186chr18:24442560ENST0000038316805156_17610324.0TransmembraneHelical
TgeneAQP4chr2:74058186chr18:24442560ENST0000038316805185_20510324.0TransmembraneHelical
TgeneAQP4chr2:74058186chr18:24442560ENST0000038316805232_25210324.0TransmembraneHelical
TgeneAQP4chr2:74058186chr18:24442560ENST000003831680537_5710324.0TransmembraneHelical
TgeneAQP4chr2:74058186chr18:24442560ENST000003831680570_8910324.0TransmembraneHelical
TgeneAQP4chr2:74058186chr18:24442560ENST0000044083205116_1360302.0TransmembraneHelical
TgeneAQP4chr2:74058186chr18:24442560ENST0000044083205156_1760302.0TransmembraneHelical
TgeneAQP4chr2:74058186chr18:24442560ENST0000044083205185_2050302.0TransmembraneHelical
TgeneAQP4chr2:74058186chr18:24442560ENST0000044083205232_2520302.0TransmembraneHelical
TgeneAQP4chr2:74058186chr18:24442560ENST000004408320537_570302.0TransmembraneHelical
TgeneAQP4chr2:74058186chr18:24442560ENST000004408320570_890302.0TransmembraneHelical
TgeneAQP4chr2:74058186chr18:24442560ENST0000058137404116_1360302.0TransmembraneHelical
TgeneAQP4chr2:74058186chr18:24442560ENST0000058137404156_1760302.0TransmembraneHelical
TgeneAQP4chr2:74058186chr18:24442560ENST0000058137404185_2050302.0TransmembraneHelical
TgeneAQP4chr2:74058186chr18:24442560ENST0000058137404232_2520302.0TransmembraneHelical
TgeneAQP4chr2:74058186chr18:24442560ENST000005813740437_570302.0TransmembraneHelical
TgeneAQP4chr2:74058186chr18:24442560ENST000005813740470_890302.0TransmembraneHelical

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneSTAMBPchr2:74058186chr18:24442560ENST00000339566+210104_17767425.0Compositional biasNote=Glu-rich
HgeneSTAMBPchr2:74058186chr18:24442560ENST00000394070+210104_17767425.0Compositional biasNote=Glu-rich
HgeneSTAMBPchr2:74058186chr18:24442560ENST00000394073+311104_17767425.0Compositional biasNote=Glu-rich
HgeneSTAMBPchr2:74058186chr18:24442560ENST00000409707+211104_17767507.3333333333333Compositional biasNote=Glu-rich
HgeneSTAMBPchr2:74058186chr18:24442560ENST00000339566+210257_38867425.0DomainMPN
HgeneSTAMBPchr2:74058186chr18:24442560ENST00000394070+210257_38867425.0DomainMPN
HgeneSTAMBPchr2:74058186chr18:24442560ENST00000394073+311257_38867425.0DomainMPN
HgeneSTAMBPchr2:74058186chr18:24442560ENST00000409707+211257_38867507.3333333333333DomainMPN
HgeneSTAMBPchr2:74058186chr18:24442560ENST00000339566+210335_34867425.0MotifJAMM motif
HgeneSTAMBPchr2:74058186chr18:24442560ENST00000394070+210335_34867425.0MotifJAMM motif
HgeneSTAMBPchr2:74058186chr18:24442560ENST00000394073+311335_34867425.0MotifJAMM motif
HgeneSTAMBPchr2:74058186chr18:24442560ENST00000409707+211335_34867507.3333333333333MotifJAMM motif
TgeneAQP4chr2:74058186chr18:24442560ENST00000383168051_3610324.0Topological domainCytoplasmic


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Fusion Gene Sequence for STAMBP-AQP4


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>87129_87129_1_STAMBP-AQP4_STAMBP_chr2_74058186_ENST00000339566_AQP4_chr18_24442560_ENST00000383168_length(transcript)=5366nt_BP=253nt
ACGTTTCCGGAACCTCCGGGTGTCATCCGCGGGGAAAGAACTTGGTCCTGATGTCTGACCATGGAGATGTGAGCCTCCCGCCCGAAGACC
GGGTGAGGGCTCTCTCCCAGCTGGGTAGTGCGGTAGAGGTGAATGAAGACATTCCACCCCGTCGGTACTTCCGCTCTGGAGTTGAGATTA
TCCGAATGGCATCCATTTACTCTGAGGAAGGCAACATTGAACATGCCTTCATCCTCTATAACAAGTATATCACTAAGTGTGGACCTTTGT
GTACCAGAGAGAACATCATGGTGGCTTTCAAAGGGGTCTGGACTCAAGCTTTCTGGAAAGCAGTCACAGCGGAATTTCTGGCCATGCTTA
TTTTTGTTCTCCTCAGCCTGGGATCCACCATCAACTGGGGTGGAACAGAAAAGCCTTTACCGGTCGACATGGTTCTCATCTCCCTTTGCT
TTGGACTCAGCATTGCAACCATGGTGCAGTGCTTTGGCCATATCAGCGGTGGCCACATCAACCCTGCAGTGACTGTGGCCATGGTGTGCA
CCAGGAAGATCAGCATCGCCAAGTCTGTCTTCTACATCGCAGCCCAGTGCCTGGGGGCCATCATTGGAGCAGGAATCCTCTATCTGGTCA
CACCTCCCAGTGTGGTGGGAGGCCTGGGAGTCACCATGGTTCATGGAAATCTTACCGCTGGTCATGGTCTCCTGGTTGAGTTGATAATCA
CATTTCAATTGGTGTTTACTATCTTTGCCAGCTGTGATTCCAAACGGACTGATGTCACTGGCTCAATAGCTTTAGCAATTGGATTTTCTG
TTGCAATTGGACATTTATTTGCAATCAATTATACTGGTGCCAGCATGAATCCCGCCCGATCCTTTGGACCTGCAGTTATCATGGGAAATT
GGGAAAACCATTGGATATATTGGGTTGGGCCCATCATAGGAGCTGTCCTCGCTGGTGGCCTTTATGAGTATGTCTTCTGTCCAGATGTTG
AATTCAAACGTCGTTTTAAAGAAGCCTTCAGCAAAGCTGCCCAGCAAACAAAAGGAAGCTACATGGAGGTGGAGGACAACAGGAGTCAGG
TAGAGACGGATGACCTGATTCTAAAACCTGGAGTGGTGCATGTGATTGACGTTGACCGGGGAGAGGAGAAGAAGGGGAAAGACCAATCTG
GAGAGGTATTGTCTTCAGTATGACTAGAAGATCGCACTGAAAGCAGACAAGACTCCTTAGAACTGTCCTCAGATTTCCTTCCACCCATTA
AGGAAACAGATTTGTTATAAATTAGAAATGTGCAGGTTTGTTGTTTCATGTCATATTACTCAGTCTAAACAATAAATATTTCATAATTTA
CAAAGGAGGAACGGAAGAAACCTATTGTGAATTCCAAATCTAAAAAAAGAAATATTTTTAAAATGTTCTTAAGCAAATATATACCTATTT
TATCTAGTTACCTTTCATTAACAACCAATTTTAACCGTGTGTCAAGATTTGGTTAAGTCTTGCCTGACAGAACTCAAAGACACGTCTATC
AGCTTATTCCTTCTCTACTGGAATATTGGTATAGTCAATTCTTATTTGAATATTTATTCTATTAAACTGAGTTTAACAATGGCAAAATAC
AGTATGTCACAGTCATGCACATTCAAGAGAGAAAATATAACAAGTTCTTTTATGAGCAATCCCTTATGCATAGACTACCTTGGCAAAAGA
GCATTAGCAAGTGTCACTGCTCATCAGTTACTTCCTTCCATTTATATCACAAATACCCAAGTTTCAATTCTAACTTCATTTCATGGTATT
TCTTCCTCCTCAATGCCCAAGGTAATGTGGGACTAAAGCCCAGAAATTTGAAAAGAATATTCAGAAATCCTTCCCAAATCATAAGGGCAC
CTATTGAGATTCAAGACAAGCAGACTCGTAAAATCTTGTAGAGGCAGAGGCAAAGTTATCATCATACAAAAATCACAAACAAAAAGGAGA
TCTGTATTCGGGTATCAAACGGTTGATCTGTTTTCAGTGCACACCCTCAAATGCACCACACCAGTTTTACGATCTAAGCTTTTAACCCCT
TTACCACTTTGCTTATTTTTAAAAAATTTATTGGCAAAACTGGGGATTTTGTTTGTAACTTTGGTTATCTATATTTAAACATTAGCTGAG
ACATATTTTTGATAACAAGAACTTAGCTAGTTGAGTCCTGGCTTTTTGTTGATTATTAAGCTGTGTTCACTCTAGAAGGTGTAAAGGCCC
TGTCCCAATCTCTGCTCTCTCACTTCTCGTGACATTTGTTGATAATCTTTACTGCAAGTGTAATGATATTTGAGTGAATTAAAATGCATG
ACAGACAAGGTACAACATGGTTGCAGAATAAAAGGGTGAGGACATCAGATCACTCTGTATTCAAAGCTTACTAGACGAACAATCTTTCAT
TTCTGGATATATTGTAGCTAACCCAACACATTTTTAAACTATTTTTGTTACTGACTCACTTACTTGTCAAAATAATTGGTTTTTCTGTCC
TGCTTTGCCTTTTGTCACTAGAATGTTCTCCAGAAACCCCAGTTTCTGTCATCTTAACTGTCTAGTCTAGCCGTTAACTTAGACAAAGAA
GTGCAAATGTCAATTTCACTAAACAAAAGCTATTAGAAGTAAAGCAGAAACCTATCACTGCAAGGAGTGACTTGTAAATAACTGATGATC
AAGGGCTGTCTTCTCTCAAGCATGGTTCCAACTCTGTGTCACTTTTTAGCGTTAATGGCAGTTGTGTGTCTGTGGCAGTGAGATAATGGA
CCACTATTAAACCTGATTCTCTTCGGTGCTAGGAAAGAGTGATGTGTGAGATTCCCAGAGAGTCGTCACACCAGTGTTATGCCTGGGAGT
GCCACTGGCATACCGCAGGTGCCTAAATCCCAGGCCCCTTTCTCAGGGGGCGTGGCCACACCACACACTGCGCCAGTGACACATAGTTAC
TTCCTGGCTGGGACGGCACCTATAGAAACTAGGGTACAAATCTCCCAAAGATGGTTTGCACCGTCATTTCAAATGTTTGCACAATATACC
ACTTAGAGGCTTAAAATCAGGGTGGTTCAGTTCAAAAGGTAATATCAACCGTCAGCAAACATGTCAGTTTAAAAATAAGTTCGGTTAACA
AGGAAGTGTTAAGCAGATTTTTTGAATACACTTACAATATACTGGCTTATAATCATTTTTATTCTGCCATATGGTTTATTTCATATACAC
TCACTTTTACACTCACTTCCAATTATAGCATTCAATAAGTTACGGTTAAAGAAAAGTGAATGGTGTTTTTGTAATTTGTTTTCTAGTAGC
TAGCAGAGAGCCTGGCACATAGTATGTATTCAAAACAAGTGTGTTAATTAATAAAAATATATAAATCTCATTTGAGATTTAAGAATATAA
ATAATTTTCTTTTAATCTTTATTTTGCTCAATATTTAATAGGAAGTATGATTTCAAGGACTACTAAAGGAAGGCAATATACATGTGAAAA
CCATAAAATACATTTTTTGCATTCTACTATTTTTAGGGGCATGAAATGAATGAAAGCTTTAGCACTTTTTTGCCCCTACATATGAGACAA
CATATTTTGTATTTCACTCAAGGCTCTGCCAGTAAAAAGTAATGAAATTGTACCTTTCTAATGACATCTATGCAGCAGGGGTCTATCGCC
TTGTGGATGGCACCAAATTATCCAAGTGTATTAGGAGACTGGGGCTTTTTTCTTTAATCCCTTCTTATTAATGAAGTGCATAGTGCTGCT
CCCAGGAGACCACTGCTGACAGATACACAGAGAAGAGATCAGAGAGGAAAAACTGGGAAGACATAAATGAATTATACCCAGCCATGAAAC
AATGCCAACTGTCTCTTCCCTAAGGAAGAGTACAAGTACCCTAAAATTGAAAGGTGGTCCCTACACTGAAAACGCACATAGTTTGTCAAA
AGTGTACAAAAGGGAAAGAGTCTTATTTTAAGCTTTCAGGCTTTCTTAAAAACTTGGGGACCAGAATTTCAATGTATGTTTCCATTGTTG
AAGATAACATTTTCTTCAAAGAGCCTTAACCTTTTGTACTGGAAGGAAATATTTTCTGGACTTAAGTAGTTGCCTAAATTTAAGATTCCT
ACACTTTATTTCTGCCATTGATGCTTTTCCTAAACCCTTATACTATCTTTTTATTATCTGAGCCTTTTCCTAATGCAGCTCATAGGTGCT
AGCTAGAGCTGCTGCTCAGTATTGAAGACTTTACAAGGAGATTAGAAATCTTTGGAAAACATATGTGATGAAATTGAGCTATATGATTTA
TCAGAGATCTGATTCCAAAGAGCACAGAATACTGTTCTCAGACCATGAAACCAGACAACACATGTATTGGTTTAAACTCGATAATGACAG
GAAAATTCCAAACTAGAGCAGTAAATTCAAATGGTAAGATGAATCCTAGAAGGCCTCTGATTGCAGCATGTTGACACCAACCTCACGTTA
CGAACAATTCACAGAGAATTTGCCTTTGTGGCAACTGAAGATGGAAGTCTGGGGGGCACAGACAACCTTATCAAACAATATAAAAGCCAA
TATAAATTCTCATAAGCACTATAGAATTTGCAAATTCAGAACATTTTATACCTAAAAGTAATTCTGTCTTTCCTAAAGTGTTTTTAACAT
GAAAATTAGTAGGAAGATGTGGTTACTATTTGGAAAGTGTAATGTAACAAAACTCTCTTTTGTTACCACAAATTTTGTGAGTTTAGTACT
CTACAGATTGCCCCATAAGAGCAGTAGCTTTTGAAACTCATAATTCTCTGAAATAAATGAAAGACATTTAATTCAAGGATCAAAAATTGT
GGCCATCTTTGCAAATGACTACCTATAGCCTGTGAAAATACATTTCAAAAAATGTTATGTGCAATGAACACTAAATTTAAGAGCAGTTAC
AGTGTGACTCACTCATGTTTAAAAAAAATCGAAGAGCTAAAAAATACGTCTAATTTATGTAACCCATTGGAATGTATTTCTAGGTTCTCT
TCAGGATTAATTAAATAAACATGCAATTTATGAAAACATATAAACAATTATTTATCACTTTTATGACCCAAATCACAATAAAATTGTCAT
TTAGGATAAACTGGGGAGAATAGACTGAACATATGGTTATATTCACAGTTATTTATTAACTTAAATGTTATTCCAACATTAGAGCTAATG
TTAAAAAGATTTAAACTGTAACGTCTAATATTTGGAATAATATATTAAAGTATTAGCACTGTGGTTGATTTTCTTGAATTATGTTGCATC

>87129_87129_1_STAMBP-AQP4_STAMBP_chr2_74058186_ENST00000339566_AQP4_chr18_24442560_ENST00000383168_length(amino acids)=383AA_BP=71
MVLMSDHGDVSLPPEDRVRALSQLGSAVEVNEDIPPRRYFRSGVEIIRMASIYSEEGNIEHAFILYNKYITKCGPLCTRENIMVAFKGVW
TQAFWKAVTAEFLAMLIFVLLSLGSTINWGGTEKPLPVDMVLISLCFGLSIATMVQCFGHISGGHINPAVTVAMVCTRKISIAKSVFYIA
AQCLGAIIGAGILYLVTPPSVVGGLGVTMVHGNLTAGHGLLVELIITFQLVFTIFASCDSKRTDVTGSIALAIGFSVAIGHLFAINYTGA
SMNPARSFGPAVIMGNWENHWIYWVGPIIGAVLAGGLYEYVFCPDVEFKRRFKEAFSKAAQQTKGSYMEVEDNRSQVETDDLILKPGVVH

--------------------------------------------------------------
>87129_87129_2_STAMBP-AQP4_STAMBP_chr2_74058186_ENST00000394070_AQP4_chr18_24442560_ENST00000383168_length(transcript)=5819nt_BP=706nt
GGTGGGGCAGGGCCTCCGAGCGTGGTTGGACTTTGAAGGGGATCGGCCGCCGTGAGTGTGGGGCCTGCAGCCTACTCTCCCCGAGTCCCC
TGCCCGGCCTGCCTCGCTCGAGGCACCCGACGGCTTCTGTCTCCGCGGGCTGGCGCCTGACCAGCCAGGCCCAGCGGTTCCCCGCCTACT
GCATTTGAAAGATCCCGAAAACCCTGGATGATTGTGCCTGGGGTTGGCAAGTTCGTCTTGAGTGCCTTCAAGAAGGGTTCCTCAAGCAGT
TGTCGATAGAGCCCTCCCTACTGTATACGCCCCCTCCGCTCATTCCTGCTACTTCCTTTCTCCTCCTCGTATTTCCCCCTCGGTCCTTTA
CGCCGCCTTTCCCCCTCATTTGCAGATGCTGCATCCCCTTTTTGGAATTGCTCAACCAGGTGGTAACCGGCGCCGCTTCCTGGCCTTGGG
AGGTGGTTCCTTTCTTAACCCACAAGAACCTCTCCCAAGAGAACTTGGTCCTGATGTCTGACCATGGAGATGTGAGCCTCCCGCCCGAAG
ACCGGGTGAGGGCTCTCTCCCAGCTGGGTAGTGCGGTAGAGGTGAATGAAGACATTCCACCCCGTCGGTACTTCCGCTCTGGAGTTGAGA
TTATCCGAATGGCATCCATTTACTCTGAGGAAGGCAACATTGAACATGCCTTCATCCTCTATAACAAGTATATCACTAAGTGTGGACCTT
TGTGTACCAGAGAGAACATCATGGTGGCTTTCAAAGGGGTCTGGACTCAAGCTTTCTGGAAAGCAGTCACAGCGGAATTTCTGGCCATGC
TTATTTTTGTTCTCCTCAGCCTGGGATCCACCATCAACTGGGGTGGAACAGAAAAGCCTTTACCGGTCGACATGGTTCTCATCTCCCTTT
GCTTTGGACTCAGCATTGCAACCATGGTGCAGTGCTTTGGCCATATCAGCGGTGGCCACATCAACCCTGCAGTGACTGTGGCCATGGTGT
GCACCAGGAAGATCAGCATCGCCAAGTCTGTCTTCTACATCGCAGCCCAGTGCCTGGGGGCCATCATTGGAGCAGGAATCCTCTATCTGG
TCACACCTCCCAGTGTGGTGGGAGGCCTGGGAGTCACCATGGTTCATGGAAATCTTACCGCTGGTCATGGTCTCCTGGTTGAGTTGATAA
TCACATTTCAATTGGTGTTTACTATCTTTGCCAGCTGTGATTCCAAACGGACTGATGTCACTGGCTCAATAGCTTTAGCAATTGGATTTT
CTGTTGCAATTGGACATTTATTTGCAATCAATTATACTGGTGCCAGCATGAATCCCGCCCGATCCTTTGGACCTGCAGTTATCATGGGAA
ATTGGGAAAACCATTGGATATATTGGGTTGGGCCCATCATAGGAGCTGTCCTCGCTGGTGGCCTTTATGAGTATGTCTTCTGTCCAGATG
TTGAATTCAAACGTCGTTTTAAAGAAGCCTTCAGCAAAGCTGCCCAGCAAACAAAAGGAAGCTACATGGAGGTGGAGGACAACAGGAGTC
AGGTAGAGACGGATGACCTGATTCTAAAACCTGGAGTGGTGCATGTGATTGACGTTGACCGGGGAGAGGAGAAGAAGGGGAAAGACCAAT
CTGGAGAGGTATTGTCTTCAGTATGACTAGAAGATCGCACTGAAAGCAGACAAGACTCCTTAGAACTGTCCTCAGATTTCCTTCCACCCA
TTAAGGAAACAGATTTGTTATAAATTAGAAATGTGCAGGTTTGTTGTTTCATGTCATATTACTCAGTCTAAACAATAAATATTTCATAAT
TTACAAAGGAGGAACGGAAGAAACCTATTGTGAATTCCAAATCTAAAAAAAGAAATATTTTTAAAATGTTCTTAAGCAAATATATACCTA
TTTTATCTAGTTACCTTTCATTAACAACCAATTTTAACCGTGTGTCAAGATTTGGTTAAGTCTTGCCTGACAGAACTCAAAGACACGTCT
ATCAGCTTATTCCTTCTCTACTGGAATATTGGTATAGTCAATTCTTATTTGAATATTTATTCTATTAAACTGAGTTTAACAATGGCAAAA
TACAGTATGTCACAGTCATGCACATTCAAGAGAGAAAATATAACAAGTTCTTTTATGAGCAATCCCTTATGCATAGACTACCTTGGCAAA
AGAGCATTAGCAAGTGTCACTGCTCATCAGTTACTTCCTTCCATTTATATCACAAATACCCAAGTTTCAATTCTAACTTCATTTCATGGT
ATTTCTTCCTCCTCAATGCCCAAGGTAATGTGGGACTAAAGCCCAGAAATTTGAAAAGAATATTCAGAAATCCTTCCCAAATCATAAGGG
CACCTATTGAGATTCAAGACAAGCAGACTCGTAAAATCTTGTAGAGGCAGAGGCAAAGTTATCATCATACAAAAATCACAAACAAAAAGG
AGATCTGTATTCGGGTATCAAACGGTTGATCTGTTTTCAGTGCACACCCTCAAATGCACCACACCAGTTTTACGATCTAAGCTTTTAACC
CCTTTACCACTTTGCTTATTTTTAAAAAATTTATTGGCAAAACTGGGGATTTTGTTTGTAACTTTGGTTATCTATATTTAAACATTAGCT
GAGACATATTTTTGATAACAAGAACTTAGCTAGTTGAGTCCTGGCTTTTTGTTGATTATTAAGCTGTGTTCACTCTAGAAGGTGTAAAGG
CCCTGTCCCAATCTCTGCTCTCTCACTTCTCGTGACATTTGTTGATAATCTTTACTGCAAGTGTAATGATATTTGAGTGAATTAAAATGC
ATGACAGACAAGGTACAACATGGTTGCAGAATAAAAGGGTGAGGACATCAGATCACTCTGTATTCAAAGCTTACTAGACGAACAATCTTT
CATTTCTGGATATATTGTAGCTAACCCAACACATTTTTAAACTATTTTTGTTACTGACTCACTTACTTGTCAAAATAATTGGTTTTTCTG
TCCTGCTTTGCCTTTTGTCACTAGAATGTTCTCCAGAAACCCCAGTTTCTGTCATCTTAACTGTCTAGTCTAGCCGTTAACTTAGACAAA
GAAGTGCAAATGTCAATTTCACTAAACAAAAGCTATTAGAAGTAAAGCAGAAACCTATCACTGCAAGGAGTGACTTGTAAATAACTGATG
ATCAAGGGCTGTCTTCTCTCAAGCATGGTTCCAACTCTGTGTCACTTTTTAGCGTTAATGGCAGTTGTGTGTCTGTGGCAGTGAGATAAT
GGACCACTATTAAACCTGATTCTCTTCGGTGCTAGGAAAGAGTGATGTGTGAGATTCCCAGAGAGTCGTCACACCAGTGTTATGCCTGGG
AGTGCCACTGGCATACCGCAGGTGCCTAAATCCCAGGCCCCTTTCTCAGGGGGCGTGGCCACACCACACACTGCGCCAGTGACACATAGT
TACTTCCTGGCTGGGACGGCACCTATAGAAACTAGGGTACAAATCTCCCAAAGATGGTTTGCACCGTCATTTCAAATGTTTGCACAATAT
ACCACTTAGAGGCTTAAAATCAGGGTGGTTCAGTTCAAAAGGTAATATCAACCGTCAGCAAACATGTCAGTTTAAAAATAAGTTCGGTTA
ACAAGGAAGTGTTAAGCAGATTTTTTGAATACACTTACAATATACTGGCTTATAATCATTTTTATTCTGCCATATGGTTTATTTCATATA
CACTCACTTTTACACTCACTTCCAATTATAGCATTCAATAAGTTACGGTTAAAGAAAAGTGAATGGTGTTTTTGTAATTTGTTTTCTAGT
AGCTAGCAGAGAGCCTGGCACATAGTATGTATTCAAAACAAGTGTGTTAATTAATAAAAATATATAAATCTCATTTGAGATTTAAGAATA
TAAATAATTTTCTTTTAATCTTTATTTTGCTCAATATTTAATAGGAAGTATGATTTCAAGGACTACTAAAGGAAGGCAATATACATGTGA
AAACCATAAAATACATTTTTTGCATTCTACTATTTTTAGGGGCATGAAATGAATGAAAGCTTTAGCACTTTTTTGCCCCTACATATGAGA
CAACATATTTTGTATTTCACTCAAGGCTCTGCCAGTAAAAAGTAATGAAATTGTACCTTTCTAATGACATCTATGCAGCAGGGGTCTATC
GCCTTGTGGATGGCACCAAATTATCCAAGTGTATTAGGAGACTGGGGCTTTTTTCTTTAATCCCTTCTTATTAATGAAGTGCATAGTGCT
GCTCCCAGGAGACCACTGCTGACAGATACACAGAGAAGAGATCAGAGAGGAAAAACTGGGAAGACATAAATGAATTATACCCAGCCATGA
AACAATGCCAACTGTCTCTTCCCTAAGGAAGAGTACAAGTACCCTAAAATTGAAAGGTGGTCCCTACACTGAAAACGCACATAGTTTGTC
AAAAGTGTACAAAAGGGAAAGAGTCTTATTTTAAGCTTTCAGGCTTTCTTAAAAACTTGGGGACCAGAATTTCAATGTATGTTTCCATTG
TTGAAGATAACATTTTCTTCAAAGAGCCTTAACCTTTTGTACTGGAAGGAAATATTTTCTGGACTTAAGTAGTTGCCTAAATTTAAGATT
CCTACACTTTATTTCTGCCATTGATGCTTTTCCTAAACCCTTATACTATCTTTTTATTATCTGAGCCTTTTCCTAATGCAGCTCATAGGT
GCTAGCTAGAGCTGCTGCTCAGTATTGAAGACTTTACAAGGAGATTAGAAATCTTTGGAAAACATATGTGATGAAATTGAGCTATATGAT
TTATCAGAGATCTGATTCCAAAGAGCACAGAATACTGTTCTCAGACCATGAAACCAGACAACACATGTATTGGTTTAAACTCGATAATGA
CAGGAAAATTCCAAACTAGAGCAGTAAATTCAAATGGTAAGATGAATCCTAGAAGGCCTCTGATTGCAGCATGTTGACACCAACCTCACG
TTACGAACAATTCACAGAGAATTTGCCTTTGTGGCAACTGAAGATGGAAGTCTGGGGGGCACAGACAACCTTATCAAACAATATAAAAGC
CAATATAAATTCTCATAAGCACTATAGAATTTGCAAATTCAGAACATTTTATACCTAAAAGTAATTCTGTCTTTCCTAAAGTGTTTTTAA
CATGAAAATTAGTAGGAAGATGTGGTTACTATTTGGAAAGTGTAATGTAACAAAACTCTCTTTTGTTACCACAAATTTTGTGAGTTTAGT
ACTCTACAGATTGCCCCATAAGAGCAGTAGCTTTTGAAACTCATAATTCTCTGAAATAAATGAAAGACATTTAATTCAAGGATCAAAAAT
TGTGGCCATCTTTGCAAATGACTACCTATAGCCTGTGAAAATACATTTCAAAAAATGTTATGTGCAATGAACACTAAATTTAAGAGCAGT
TACAGTGTGACTCACTCATGTTTAAAAAAAATCGAAGAGCTAAAAAATACGTCTAATTTATGTAACCCATTGGAATGTATTTCTAGGTTC
TCTTCAGGATTAATTAAATAAACATGCAATTTATGAAAACATATAAACAATTATTTATCACTTTTATGACCCAAATCACAATAAAATTGT
CATTTAGGATAAACTGGGGAGAATAGACTGAACATATGGTTATATTCACAGTTATTTATTAACTTAAATGTTATTCCAACATTAGAGCTA
ATGTTAAAAAGATTTAAACTGTAACGTCTAATATTTGGAATAATATATTAAAGTATTAGCACTGTGGTTGATTTTCTTGAATTATGTTGC

>87129_87129_2_STAMBP-AQP4_STAMBP_chr2_74058186_ENST00000394070_AQP4_chr18_24442560_ENST00000383168_length(amino acids)=480AA_BP=168
MDDCAWGWQVRLECLQEGFLKQLSIEPSLLYTPPPLIPATSFLLLVFPPRSFTPPFPLICRCCIPFLELLNQVVTGAASWPWEVVPFLTH
KNLSQENLVLMSDHGDVSLPPEDRVRALSQLGSAVEVNEDIPPRRYFRSGVEIIRMASIYSEEGNIEHAFILYNKYITKCGPLCTRENIM
VAFKGVWTQAFWKAVTAEFLAMLIFVLLSLGSTINWGGTEKPLPVDMVLISLCFGLSIATMVQCFGHISGGHINPAVTVAMVCTRKISIA
KSVFYIAAQCLGAIIGAGILYLVTPPSVVGGLGVTMVHGNLTAGHGLLVELIITFQLVFTIFASCDSKRTDVTGSIALAIGFSVAIGHLF
AINYTGASMNPARSFGPAVIMGNWENHWIYWVGPIIGAVLAGGLYEYVFCPDVEFKRRFKEAFSKAAQQTKGSYMEVEDNRSQVETDDLI

--------------------------------------------------------------
>87129_87129_3_STAMBP-AQP4_STAMBP_chr2_74058186_ENST00000394073_AQP4_chr18_24442560_ENST00000383168_length(transcript)=5505nt_BP=392nt
GGGAAGGGTCCCGGGAACGTGGTGGGGCAGGGCCTCCGAGCGTGGTTGGACTTTGAAGGGGATCGGCCGCCATGCTGCATCCCCTTTTTG
GAATTGCTCAACCAGGTGGTAACCGGCGCCGCTTCCTGGCCTTGGGAGGTGGTTCCTTTCTTAACCCACAAGAACCTCTCCCAAGAGAAC
TTGGTCCTGATGTCTGACCATGGAGATGTGAGCCTCCCGCCCGAAGACCGGGTGAGGGCTCTCTCCCAGCTGGGTAGTGCGGTAGAGGTG
AATGAAGACATTCCACCCCGTCGGTACTTCCGCTCTGGAGTTGAGATTATCCGAATGGCATCCATTTACTCTGAGGAAGGCAACATTGAA
CATGCCTTCATCCTCTATAACAAGTATATCACTAAGTGTGGACCTTTGTGTACCAGAGAGAACATCATGGTGGCTTTCAAAGGGGTCTGG
ACTCAAGCTTTCTGGAAAGCAGTCACAGCGGAATTTCTGGCCATGCTTATTTTTGTTCTCCTCAGCCTGGGATCCACCATCAACTGGGGT
GGAACAGAAAAGCCTTTACCGGTCGACATGGTTCTCATCTCCCTTTGCTTTGGACTCAGCATTGCAACCATGGTGCAGTGCTTTGGCCAT
ATCAGCGGTGGCCACATCAACCCTGCAGTGACTGTGGCCATGGTGTGCACCAGGAAGATCAGCATCGCCAAGTCTGTCTTCTACATCGCA
GCCCAGTGCCTGGGGGCCATCATTGGAGCAGGAATCCTCTATCTGGTCACACCTCCCAGTGTGGTGGGAGGCCTGGGAGTCACCATGGTT
CATGGAAATCTTACCGCTGGTCATGGTCTCCTGGTTGAGTTGATAATCACATTTCAATTGGTGTTTACTATCTTTGCCAGCTGTGATTCC
AAACGGACTGATGTCACTGGCTCAATAGCTTTAGCAATTGGATTTTCTGTTGCAATTGGACATTTATTTGCAATCAATTATACTGGTGCC
AGCATGAATCCCGCCCGATCCTTTGGACCTGCAGTTATCATGGGAAATTGGGAAAACCATTGGATATATTGGGTTGGGCCCATCATAGGA
GCTGTCCTCGCTGGTGGCCTTTATGAGTATGTCTTCTGTCCAGATGTTGAATTCAAACGTCGTTTTAAAGAAGCCTTCAGCAAAGCTGCC
CAGCAAACAAAAGGAAGCTACATGGAGGTGGAGGACAACAGGAGTCAGGTAGAGACGGATGACCTGATTCTAAAACCTGGAGTGGTGCAT
GTGATTGACGTTGACCGGGGAGAGGAGAAGAAGGGGAAAGACCAATCTGGAGAGGTATTGTCTTCAGTATGACTAGAAGATCGCACTGAA
AGCAGACAAGACTCCTTAGAACTGTCCTCAGATTTCCTTCCACCCATTAAGGAAACAGATTTGTTATAAATTAGAAATGTGCAGGTTTGT
TGTTTCATGTCATATTACTCAGTCTAAACAATAAATATTTCATAATTTACAAAGGAGGAACGGAAGAAACCTATTGTGAATTCCAAATCT
AAAAAAAGAAATATTTTTAAAATGTTCTTAAGCAAATATATACCTATTTTATCTAGTTACCTTTCATTAACAACCAATTTTAACCGTGTG
TCAAGATTTGGTTAAGTCTTGCCTGACAGAACTCAAAGACACGTCTATCAGCTTATTCCTTCTCTACTGGAATATTGGTATAGTCAATTC
TTATTTGAATATTTATTCTATTAAACTGAGTTTAACAATGGCAAAATACAGTATGTCACAGTCATGCACATTCAAGAGAGAAAATATAAC
AAGTTCTTTTATGAGCAATCCCTTATGCATAGACTACCTTGGCAAAAGAGCATTAGCAAGTGTCACTGCTCATCAGTTACTTCCTTCCAT
TTATATCACAAATACCCAAGTTTCAATTCTAACTTCATTTCATGGTATTTCTTCCTCCTCAATGCCCAAGGTAATGTGGGACTAAAGCCC
AGAAATTTGAAAAGAATATTCAGAAATCCTTCCCAAATCATAAGGGCACCTATTGAGATTCAAGACAAGCAGACTCGTAAAATCTTGTAG
AGGCAGAGGCAAAGTTATCATCATACAAAAATCACAAACAAAAAGGAGATCTGTATTCGGGTATCAAACGGTTGATCTGTTTTCAGTGCA
CACCCTCAAATGCACCACACCAGTTTTACGATCTAAGCTTTTAACCCCTTTACCACTTTGCTTATTTTTAAAAAATTTATTGGCAAAACT
GGGGATTTTGTTTGTAACTTTGGTTATCTATATTTAAACATTAGCTGAGACATATTTTTGATAACAAGAACTTAGCTAGTTGAGTCCTGG
CTTTTTGTTGATTATTAAGCTGTGTTCACTCTAGAAGGTGTAAAGGCCCTGTCCCAATCTCTGCTCTCTCACTTCTCGTGACATTTGTTG
ATAATCTTTACTGCAAGTGTAATGATATTTGAGTGAATTAAAATGCATGACAGACAAGGTACAACATGGTTGCAGAATAAAAGGGTGAGG
ACATCAGATCACTCTGTATTCAAAGCTTACTAGACGAACAATCTTTCATTTCTGGATATATTGTAGCTAACCCAACACATTTTTAAACTA
TTTTTGTTACTGACTCACTTACTTGTCAAAATAATTGGTTTTTCTGTCCTGCTTTGCCTTTTGTCACTAGAATGTTCTCCAGAAACCCCA
GTTTCTGTCATCTTAACTGTCTAGTCTAGCCGTTAACTTAGACAAAGAAGTGCAAATGTCAATTTCACTAAACAAAAGCTATTAGAAGTA
AAGCAGAAACCTATCACTGCAAGGAGTGACTTGTAAATAACTGATGATCAAGGGCTGTCTTCTCTCAAGCATGGTTCCAACTCTGTGTCA
CTTTTTAGCGTTAATGGCAGTTGTGTGTCTGTGGCAGTGAGATAATGGACCACTATTAAACCTGATTCTCTTCGGTGCTAGGAAAGAGTG
ATGTGTGAGATTCCCAGAGAGTCGTCACACCAGTGTTATGCCTGGGAGTGCCACTGGCATACCGCAGGTGCCTAAATCCCAGGCCCCTTT
CTCAGGGGGCGTGGCCACACCACACACTGCGCCAGTGACACATAGTTACTTCCTGGCTGGGACGGCACCTATAGAAACTAGGGTACAAAT
CTCCCAAAGATGGTTTGCACCGTCATTTCAAATGTTTGCACAATATACCACTTAGAGGCTTAAAATCAGGGTGGTTCAGTTCAAAAGGTA
ATATCAACCGTCAGCAAACATGTCAGTTTAAAAATAAGTTCGGTTAACAAGGAAGTGTTAAGCAGATTTTTTGAATACACTTACAATATA
CTGGCTTATAATCATTTTTATTCTGCCATATGGTTTATTTCATATACACTCACTTTTACACTCACTTCCAATTATAGCATTCAATAAGTT
ACGGTTAAAGAAAAGTGAATGGTGTTTTTGTAATTTGTTTTCTAGTAGCTAGCAGAGAGCCTGGCACATAGTATGTATTCAAAACAAGTG
TGTTAATTAATAAAAATATATAAATCTCATTTGAGATTTAAGAATATAAATAATTTTCTTTTAATCTTTATTTTGCTCAATATTTAATAG
GAAGTATGATTTCAAGGACTACTAAAGGAAGGCAATATACATGTGAAAACCATAAAATACATTTTTTGCATTCTACTATTTTTAGGGGCA
TGAAATGAATGAAAGCTTTAGCACTTTTTTGCCCCTACATATGAGACAACATATTTTGTATTTCACTCAAGGCTCTGCCAGTAAAAAGTA
ATGAAATTGTACCTTTCTAATGACATCTATGCAGCAGGGGTCTATCGCCTTGTGGATGGCACCAAATTATCCAAGTGTATTAGGAGACTG
GGGCTTTTTTCTTTAATCCCTTCTTATTAATGAAGTGCATAGTGCTGCTCCCAGGAGACCACTGCTGACAGATACACAGAGAAGAGATCA
GAGAGGAAAAACTGGGAAGACATAAATGAATTATACCCAGCCATGAAACAATGCCAACTGTCTCTTCCCTAAGGAAGAGTACAAGTACCC
TAAAATTGAAAGGTGGTCCCTACACTGAAAACGCACATAGTTTGTCAAAAGTGTACAAAAGGGAAAGAGTCTTATTTTAAGCTTTCAGGC
TTTCTTAAAAACTTGGGGACCAGAATTTCAATGTATGTTTCCATTGTTGAAGATAACATTTTCTTCAAAGAGCCTTAACCTTTTGTACTG
GAAGGAAATATTTTCTGGACTTAAGTAGTTGCCTAAATTTAAGATTCCTACACTTTATTTCTGCCATTGATGCTTTTCCTAAACCCTTAT
ACTATCTTTTTATTATCTGAGCCTTTTCCTAATGCAGCTCATAGGTGCTAGCTAGAGCTGCTGCTCAGTATTGAAGACTTTACAAGGAGA
TTAGAAATCTTTGGAAAACATATGTGATGAAATTGAGCTATATGATTTATCAGAGATCTGATTCCAAAGAGCACAGAATACTGTTCTCAG
ACCATGAAACCAGACAACACATGTATTGGTTTAAACTCGATAATGACAGGAAAATTCCAAACTAGAGCAGTAAATTCAAATGGTAAGATG
AATCCTAGAAGGCCTCTGATTGCAGCATGTTGACACCAACCTCACGTTACGAACAATTCACAGAGAATTTGCCTTTGTGGCAACTGAAGA
TGGAAGTCTGGGGGGCACAGACAACCTTATCAAACAATATAAAAGCCAATATAAATTCTCATAAGCACTATAGAATTTGCAAATTCAGAA
CATTTTATACCTAAAAGTAATTCTGTCTTTCCTAAAGTGTTTTTAACATGAAAATTAGTAGGAAGATGTGGTTACTATTTGGAAAGTGTA
ATGTAACAAAACTCTCTTTTGTTACCACAAATTTTGTGAGTTTAGTACTCTACAGATTGCCCCATAAGAGCAGTAGCTTTTGAAACTCAT
AATTCTCTGAAATAAATGAAAGACATTTAATTCAAGGATCAAAAATTGTGGCCATCTTTGCAAATGACTACCTATAGCCTGTGAAAATAC
ATTTCAAAAAATGTTATGTGCAATGAACACTAAATTTAAGAGCAGTTACAGTGTGACTCACTCATGTTTAAAAAAAATCGAAGAGCTAAA
AAATACGTCTAATTTATGTAACCCATTGGAATGTATTTCTAGGTTCTCTTCAGGATTAATTAAATAAACATGCAATTTATGAAAACATAT
AAACAATTATTTATCACTTTTATGACCCAAATCACAATAAAATTGTCATTTAGGATAAACTGGGGAGAATAGACTGAACATATGGTTATA
TTCACAGTTATTTATTAACTTAAATGTTATTCCAACATTAGAGCTAATGTTAAAAAGATTTAAACTGTAACGTCTAATATTTGGAATAAT
ATATTAAAGTATTAGCACTGTGGTTGATTTTCTTGAATTATGTTGCATCTTGTACTACTAAGCTTGTGAAAATAAACATTTGGATGTTTT

>87129_87129_3_STAMBP-AQP4_STAMBP_chr2_74058186_ENST00000394073_AQP4_chr18_24442560_ENST00000383168_length(amino acids)=428AA_BP=116
MDFEGDRPPCCIPFLELLNQVVTGAASWPWEVVPFLTHKNLSQENLVLMSDHGDVSLPPEDRVRALSQLGSAVEVNEDIPPRRYFRSGVE
IIRMASIYSEEGNIEHAFILYNKYITKCGPLCTRENIMVAFKGVWTQAFWKAVTAEFLAMLIFVLLSLGSTINWGGTEKPLPVDMVLISL
CFGLSIATMVQCFGHISGGHINPAVTVAMVCTRKISIAKSVFYIAAQCLGAIIGAGILYLVTPPSVVGGLGVTMVHGNLTAGHGLLVELI
ITFQLVFTIFASCDSKRTDVTGSIALAIGFSVAIGHLFAINYTGASMNPARSFGPAVIMGNWENHWIYWVGPIIGAVLAGGLYEYVFCPD

--------------------------------------------------------------
>87129_87129_4_STAMBP-AQP4_STAMBP_chr2_74058186_ENST00000409707_AQP4_chr18_24442560_ENST00000383168_length(transcript)=5363nt_BP=250nt
TTTCCGGAACCTCCGGGTGTCATCCGCGGGGAAAGAACTTGGTCCTGATGTCTGACCATGGAGATGTGAGCCTCCCGCCCGAAGACCGGG
TGAGGGCTCTCTCCCAGCTGGGTAGTGCGGTAGAGGTGAATGAAGACATTCCACCCCGTCGGTACTTCCGCTCTGGAGTTGAGATTATCC
GAATGGCATCCATTTACTCTGAGGAAGGCAACATTGAACATGCCTTCATCCTCTATAACAAGTATATCACTAAGTGTGGACCTTTGTGTA
CCAGAGAGAACATCATGGTGGCTTTCAAAGGGGTCTGGACTCAAGCTTTCTGGAAAGCAGTCACAGCGGAATTTCTGGCCATGCTTATTT
TTGTTCTCCTCAGCCTGGGATCCACCATCAACTGGGGTGGAACAGAAAAGCCTTTACCGGTCGACATGGTTCTCATCTCCCTTTGCTTTG
GACTCAGCATTGCAACCATGGTGCAGTGCTTTGGCCATATCAGCGGTGGCCACATCAACCCTGCAGTGACTGTGGCCATGGTGTGCACCA
GGAAGATCAGCATCGCCAAGTCTGTCTTCTACATCGCAGCCCAGTGCCTGGGGGCCATCATTGGAGCAGGAATCCTCTATCTGGTCACAC
CTCCCAGTGTGGTGGGAGGCCTGGGAGTCACCATGGTTCATGGAAATCTTACCGCTGGTCATGGTCTCCTGGTTGAGTTGATAATCACAT
TTCAATTGGTGTTTACTATCTTTGCCAGCTGTGATTCCAAACGGACTGATGTCACTGGCTCAATAGCTTTAGCAATTGGATTTTCTGTTG
CAATTGGACATTTATTTGCAATCAATTATACTGGTGCCAGCATGAATCCCGCCCGATCCTTTGGACCTGCAGTTATCATGGGAAATTGGG
AAAACCATTGGATATATTGGGTTGGGCCCATCATAGGAGCTGTCCTCGCTGGTGGCCTTTATGAGTATGTCTTCTGTCCAGATGTTGAAT
TCAAACGTCGTTTTAAAGAAGCCTTCAGCAAAGCTGCCCAGCAAACAAAAGGAAGCTACATGGAGGTGGAGGACAACAGGAGTCAGGTAG
AGACGGATGACCTGATTCTAAAACCTGGAGTGGTGCATGTGATTGACGTTGACCGGGGAGAGGAGAAGAAGGGGAAAGACCAATCTGGAG
AGGTATTGTCTTCAGTATGACTAGAAGATCGCACTGAAAGCAGACAAGACTCCTTAGAACTGTCCTCAGATTTCCTTCCACCCATTAAGG
AAACAGATTTGTTATAAATTAGAAATGTGCAGGTTTGTTGTTTCATGTCATATTACTCAGTCTAAACAATAAATATTTCATAATTTACAA
AGGAGGAACGGAAGAAACCTATTGTGAATTCCAAATCTAAAAAAAGAAATATTTTTAAAATGTTCTTAAGCAAATATATACCTATTTTAT
CTAGTTACCTTTCATTAACAACCAATTTTAACCGTGTGTCAAGATTTGGTTAAGTCTTGCCTGACAGAACTCAAAGACACGTCTATCAGC
TTATTCCTTCTCTACTGGAATATTGGTATAGTCAATTCTTATTTGAATATTTATTCTATTAAACTGAGTTTAACAATGGCAAAATACAGT
ATGTCACAGTCATGCACATTCAAGAGAGAAAATATAACAAGTTCTTTTATGAGCAATCCCTTATGCATAGACTACCTTGGCAAAAGAGCA
TTAGCAAGTGTCACTGCTCATCAGTTACTTCCTTCCATTTATATCACAAATACCCAAGTTTCAATTCTAACTTCATTTCATGGTATTTCT
TCCTCCTCAATGCCCAAGGTAATGTGGGACTAAAGCCCAGAAATTTGAAAAGAATATTCAGAAATCCTTCCCAAATCATAAGGGCACCTA
TTGAGATTCAAGACAAGCAGACTCGTAAAATCTTGTAGAGGCAGAGGCAAAGTTATCATCATACAAAAATCACAAACAAAAAGGAGATCT
GTATTCGGGTATCAAACGGTTGATCTGTTTTCAGTGCACACCCTCAAATGCACCACACCAGTTTTACGATCTAAGCTTTTAACCCCTTTA
CCACTTTGCTTATTTTTAAAAAATTTATTGGCAAAACTGGGGATTTTGTTTGTAACTTTGGTTATCTATATTTAAACATTAGCTGAGACA
TATTTTTGATAACAAGAACTTAGCTAGTTGAGTCCTGGCTTTTTGTTGATTATTAAGCTGTGTTCACTCTAGAAGGTGTAAAGGCCCTGT
CCCAATCTCTGCTCTCTCACTTCTCGTGACATTTGTTGATAATCTTTACTGCAAGTGTAATGATATTTGAGTGAATTAAAATGCATGACA
GACAAGGTACAACATGGTTGCAGAATAAAAGGGTGAGGACATCAGATCACTCTGTATTCAAAGCTTACTAGACGAACAATCTTTCATTTC
TGGATATATTGTAGCTAACCCAACACATTTTTAAACTATTTTTGTTACTGACTCACTTACTTGTCAAAATAATTGGTTTTTCTGTCCTGC
TTTGCCTTTTGTCACTAGAATGTTCTCCAGAAACCCCAGTTTCTGTCATCTTAACTGTCTAGTCTAGCCGTTAACTTAGACAAAGAAGTG
CAAATGTCAATTTCACTAAACAAAAGCTATTAGAAGTAAAGCAGAAACCTATCACTGCAAGGAGTGACTTGTAAATAACTGATGATCAAG
GGCTGTCTTCTCTCAAGCATGGTTCCAACTCTGTGTCACTTTTTAGCGTTAATGGCAGTTGTGTGTCTGTGGCAGTGAGATAATGGACCA
CTATTAAACCTGATTCTCTTCGGTGCTAGGAAAGAGTGATGTGTGAGATTCCCAGAGAGTCGTCACACCAGTGTTATGCCTGGGAGTGCC
ACTGGCATACCGCAGGTGCCTAAATCCCAGGCCCCTTTCTCAGGGGGCGTGGCCACACCACACACTGCGCCAGTGACACATAGTTACTTC
CTGGCTGGGACGGCACCTATAGAAACTAGGGTACAAATCTCCCAAAGATGGTTTGCACCGTCATTTCAAATGTTTGCACAATATACCACT
TAGAGGCTTAAAATCAGGGTGGTTCAGTTCAAAAGGTAATATCAACCGTCAGCAAACATGTCAGTTTAAAAATAAGTTCGGTTAACAAGG
AAGTGTTAAGCAGATTTTTTGAATACACTTACAATATACTGGCTTATAATCATTTTTATTCTGCCATATGGTTTATTTCATATACACTCA
CTTTTACACTCACTTCCAATTATAGCATTCAATAAGTTACGGTTAAAGAAAAGTGAATGGTGTTTTTGTAATTTGTTTTCTAGTAGCTAG
CAGAGAGCCTGGCACATAGTATGTATTCAAAACAAGTGTGTTAATTAATAAAAATATATAAATCTCATTTGAGATTTAAGAATATAAATA
ATTTTCTTTTAATCTTTATTTTGCTCAATATTTAATAGGAAGTATGATTTCAAGGACTACTAAAGGAAGGCAATATACATGTGAAAACCA
TAAAATACATTTTTTGCATTCTACTATTTTTAGGGGCATGAAATGAATGAAAGCTTTAGCACTTTTTTGCCCCTACATATGAGACAACAT
ATTTTGTATTTCACTCAAGGCTCTGCCAGTAAAAAGTAATGAAATTGTACCTTTCTAATGACATCTATGCAGCAGGGGTCTATCGCCTTG
TGGATGGCACCAAATTATCCAAGTGTATTAGGAGACTGGGGCTTTTTTCTTTAATCCCTTCTTATTAATGAAGTGCATAGTGCTGCTCCC
AGGAGACCACTGCTGACAGATACACAGAGAAGAGATCAGAGAGGAAAAACTGGGAAGACATAAATGAATTATACCCAGCCATGAAACAAT
GCCAACTGTCTCTTCCCTAAGGAAGAGTACAAGTACCCTAAAATTGAAAGGTGGTCCCTACACTGAAAACGCACATAGTTTGTCAAAAGT
GTACAAAAGGGAAAGAGTCTTATTTTAAGCTTTCAGGCTTTCTTAAAAACTTGGGGACCAGAATTTCAATGTATGTTTCCATTGTTGAAG
ATAACATTTTCTTCAAAGAGCCTTAACCTTTTGTACTGGAAGGAAATATTTTCTGGACTTAAGTAGTTGCCTAAATTTAAGATTCCTACA
CTTTATTTCTGCCATTGATGCTTTTCCTAAACCCTTATACTATCTTTTTATTATCTGAGCCTTTTCCTAATGCAGCTCATAGGTGCTAGC
TAGAGCTGCTGCTCAGTATTGAAGACTTTACAAGGAGATTAGAAATCTTTGGAAAACATATGTGATGAAATTGAGCTATATGATTTATCA
GAGATCTGATTCCAAAGAGCACAGAATACTGTTCTCAGACCATGAAACCAGACAACACATGTATTGGTTTAAACTCGATAATGACAGGAA
AATTCCAAACTAGAGCAGTAAATTCAAATGGTAAGATGAATCCTAGAAGGCCTCTGATTGCAGCATGTTGACACCAACCTCACGTTACGA
ACAATTCACAGAGAATTTGCCTTTGTGGCAACTGAAGATGGAAGTCTGGGGGGCACAGACAACCTTATCAAACAATATAAAAGCCAATAT
AAATTCTCATAAGCACTATAGAATTTGCAAATTCAGAACATTTTATACCTAAAAGTAATTCTGTCTTTCCTAAAGTGTTTTTAACATGAA
AATTAGTAGGAAGATGTGGTTACTATTTGGAAAGTGTAATGTAACAAAACTCTCTTTTGTTACCACAAATTTTGTGAGTTTAGTACTCTA
CAGATTGCCCCATAAGAGCAGTAGCTTTTGAAACTCATAATTCTCTGAAATAAATGAAAGACATTTAATTCAAGGATCAAAAATTGTGGC
CATCTTTGCAAATGACTACCTATAGCCTGTGAAAATACATTTCAAAAAATGTTATGTGCAATGAACACTAAATTTAAGAGCAGTTACAGT
GTGACTCACTCATGTTTAAAAAAAATCGAAGAGCTAAAAAATACGTCTAATTTATGTAACCCATTGGAATGTATTTCTAGGTTCTCTTCA
GGATTAATTAAATAAACATGCAATTTATGAAAACATATAAACAATTATTTATCACTTTTATGACCCAAATCACAATAAAATTGTCATTTA
GGATAAACTGGGGAGAATAGACTGAACATATGGTTATATTCACAGTTATTTATTAACTTAAATGTTATTCCAACATTAGAGCTAATGTTA
AAAAGATTTAAACTGTAACGTCTAATATTTGGAATAATATATTAAAGTATTAGCACTGTGGTTGATTTTCTTGAATTATGTTGCATCTTG

>87129_87129_4_STAMBP-AQP4_STAMBP_chr2_74058186_ENST00000409707_AQP4_chr18_24442560_ENST00000383168_length(amino acids)=383AA_BP=71
MVLMSDHGDVSLPPEDRVRALSQLGSAVEVNEDIPPRRYFRSGVEIIRMASIYSEEGNIEHAFILYNKYITKCGPLCTRENIMVAFKGVW
TQAFWKAVTAEFLAMLIFVLLSLGSTINWGGTEKPLPVDMVLISLCFGLSIATMVQCFGHISGGHINPAVTVAMVCTRKISIAKSVFYIA
AQCLGAIIGAGILYLVTPPSVVGGLGVTMVHGNLTAGHGLLVELIITFQLVFTIFASCDSKRTDVTGSIALAIGFSVAIGHLFAINYTGA
SMNPARSFGPAVIMGNWENHWIYWVGPIIGAVLAGGLYEYVFCPDVEFKRRFKEAFSKAAQQTKGSYMEVEDNRSQVETDDLILKPGVVH

--------------------------------------------------------------
>87129_87129_5_STAMBP-AQP4_STAMBP_chr2_74058186_ENST00000536064_AQP4_chr18_24442560_ENST00000383168_length(transcript)=5474nt_BP=361nt
GCCTCCGAGCGTGGTTGGACTTTGAAGGGGATCGGCCGCCATGCTGCATCCCCTTTTTGGAATTGCTCAACCAGGTGGTAACCGGCGCCG
CTTCCTGGCCTTGGGAGGTGGTTCCTTTCTTAACCCACAAGAACCTCTCCCAAGAGAACTTGGTCCTGATGTCTGACCATGGAGATGTGA
GCCTCCCGCCCGAAGACCGGGTGAGGGCTCTCTCCCAGCTGGGTAGTGCGGTAGAGGTGAATGAAGACATTCCACCCCGTCGGTACTTCC
GCTCTGGAGTTGAGATTATCCGAATGGCATCCATTTACTCTGAGGAAGGCAACATTGAACATGCCTTCATCCTCTATAACAAGTATATCA
CTAAGTGTGGACCTTTGTGTACCAGAGAGAACATCATGGTGGCTTTCAAAGGGGTCTGGACTCAAGCTTTCTGGAAAGCAGTCACAGCGG
AATTTCTGGCCATGCTTATTTTTGTTCTCCTCAGCCTGGGATCCACCATCAACTGGGGTGGAACAGAAAAGCCTTTACCGGTCGACATGG
TTCTCATCTCCCTTTGCTTTGGACTCAGCATTGCAACCATGGTGCAGTGCTTTGGCCATATCAGCGGTGGCCACATCAACCCTGCAGTGA
CTGTGGCCATGGTGTGCACCAGGAAGATCAGCATCGCCAAGTCTGTCTTCTACATCGCAGCCCAGTGCCTGGGGGCCATCATTGGAGCAG
GAATCCTCTATCTGGTCACACCTCCCAGTGTGGTGGGAGGCCTGGGAGTCACCATGGTTCATGGAAATCTTACCGCTGGTCATGGTCTCC
TGGTTGAGTTGATAATCACATTTCAATTGGTGTTTACTATCTTTGCCAGCTGTGATTCCAAACGGACTGATGTCACTGGCTCAATAGCTT
TAGCAATTGGATTTTCTGTTGCAATTGGACATTTATTTGCAATCAATTATACTGGTGCCAGCATGAATCCCGCCCGATCCTTTGGACCTG
CAGTTATCATGGGAAATTGGGAAAACCATTGGATATATTGGGTTGGGCCCATCATAGGAGCTGTCCTCGCTGGTGGCCTTTATGAGTATG
TCTTCTGTCCAGATGTTGAATTCAAACGTCGTTTTAAAGAAGCCTTCAGCAAAGCTGCCCAGCAAACAAAAGGAAGCTACATGGAGGTGG
AGGACAACAGGAGTCAGGTAGAGACGGATGACCTGATTCTAAAACCTGGAGTGGTGCATGTGATTGACGTTGACCGGGGAGAGGAGAAGA
AGGGGAAAGACCAATCTGGAGAGGTATTGTCTTCAGTATGACTAGAAGATCGCACTGAAAGCAGACAAGACTCCTTAGAACTGTCCTCAG
ATTTCCTTCCACCCATTAAGGAAACAGATTTGTTATAAATTAGAAATGTGCAGGTTTGTTGTTTCATGTCATATTACTCAGTCTAAACAA
TAAATATTTCATAATTTACAAAGGAGGAACGGAAGAAACCTATTGTGAATTCCAAATCTAAAAAAAGAAATATTTTTAAAATGTTCTTAA
GCAAATATATACCTATTTTATCTAGTTACCTTTCATTAACAACCAATTTTAACCGTGTGTCAAGATTTGGTTAAGTCTTGCCTGACAGAA
CTCAAAGACACGTCTATCAGCTTATTCCTTCTCTACTGGAATATTGGTATAGTCAATTCTTATTTGAATATTTATTCTATTAAACTGAGT
TTAACAATGGCAAAATACAGTATGTCACAGTCATGCACATTCAAGAGAGAAAATATAACAAGTTCTTTTATGAGCAATCCCTTATGCATA
GACTACCTTGGCAAAAGAGCATTAGCAAGTGTCACTGCTCATCAGTTACTTCCTTCCATTTATATCACAAATACCCAAGTTTCAATTCTA
ACTTCATTTCATGGTATTTCTTCCTCCTCAATGCCCAAGGTAATGTGGGACTAAAGCCCAGAAATTTGAAAAGAATATTCAGAAATCCTT
CCCAAATCATAAGGGCACCTATTGAGATTCAAGACAAGCAGACTCGTAAAATCTTGTAGAGGCAGAGGCAAAGTTATCATCATACAAAAA
TCACAAACAAAAAGGAGATCTGTATTCGGGTATCAAACGGTTGATCTGTTTTCAGTGCACACCCTCAAATGCACCACACCAGTTTTACGA
TCTAAGCTTTTAACCCCTTTACCACTTTGCTTATTTTTAAAAAATTTATTGGCAAAACTGGGGATTTTGTTTGTAACTTTGGTTATCTAT
ATTTAAACATTAGCTGAGACATATTTTTGATAACAAGAACTTAGCTAGTTGAGTCCTGGCTTTTTGTTGATTATTAAGCTGTGTTCACTC
TAGAAGGTGTAAAGGCCCTGTCCCAATCTCTGCTCTCTCACTTCTCGTGACATTTGTTGATAATCTTTACTGCAAGTGTAATGATATTTG
AGTGAATTAAAATGCATGACAGACAAGGTACAACATGGTTGCAGAATAAAAGGGTGAGGACATCAGATCACTCTGTATTCAAAGCTTACT
AGACGAACAATCTTTCATTTCTGGATATATTGTAGCTAACCCAACACATTTTTAAACTATTTTTGTTACTGACTCACTTACTTGTCAAAA
TAATTGGTTTTTCTGTCCTGCTTTGCCTTTTGTCACTAGAATGTTCTCCAGAAACCCCAGTTTCTGTCATCTTAACTGTCTAGTCTAGCC
GTTAACTTAGACAAAGAAGTGCAAATGTCAATTTCACTAAACAAAAGCTATTAGAAGTAAAGCAGAAACCTATCACTGCAAGGAGTGACT
TGTAAATAACTGATGATCAAGGGCTGTCTTCTCTCAAGCATGGTTCCAACTCTGTGTCACTTTTTAGCGTTAATGGCAGTTGTGTGTCTG
TGGCAGTGAGATAATGGACCACTATTAAACCTGATTCTCTTCGGTGCTAGGAAAGAGTGATGTGTGAGATTCCCAGAGAGTCGTCACACC
AGTGTTATGCCTGGGAGTGCCACTGGCATACCGCAGGTGCCTAAATCCCAGGCCCCTTTCTCAGGGGGCGTGGCCACACCACACACTGCG
CCAGTGACACATAGTTACTTCCTGGCTGGGACGGCACCTATAGAAACTAGGGTACAAATCTCCCAAAGATGGTTTGCACCGTCATTTCAA
ATGTTTGCACAATATACCACTTAGAGGCTTAAAATCAGGGTGGTTCAGTTCAAAAGGTAATATCAACCGTCAGCAAACATGTCAGTTTAA
AAATAAGTTCGGTTAACAAGGAAGTGTTAAGCAGATTTTTTGAATACACTTACAATATACTGGCTTATAATCATTTTTATTCTGCCATAT
GGTTTATTTCATATACACTCACTTTTACACTCACTTCCAATTATAGCATTCAATAAGTTACGGTTAAAGAAAAGTGAATGGTGTTTTTGT
AATTTGTTTTCTAGTAGCTAGCAGAGAGCCTGGCACATAGTATGTATTCAAAACAAGTGTGTTAATTAATAAAAATATATAAATCTCATT
TGAGATTTAAGAATATAAATAATTTTCTTTTAATCTTTATTTTGCTCAATATTTAATAGGAAGTATGATTTCAAGGACTACTAAAGGAAG
GCAATATACATGTGAAAACCATAAAATACATTTTTTGCATTCTACTATTTTTAGGGGCATGAAATGAATGAAAGCTTTAGCACTTTTTTG
CCCCTACATATGAGACAACATATTTTGTATTTCACTCAAGGCTCTGCCAGTAAAAAGTAATGAAATTGTACCTTTCTAATGACATCTATG
CAGCAGGGGTCTATCGCCTTGTGGATGGCACCAAATTATCCAAGTGTATTAGGAGACTGGGGCTTTTTTCTTTAATCCCTTCTTATTAAT
GAAGTGCATAGTGCTGCTCCCAGGAGACCACTGCTGACAGATACACAGAGAAGAGATCAGAGAGGAAAAACTGGGAAGACATAAATGAAT
TATACCCAGCCATGAAACAATGCCAACTGTCTCTTCCCTAAGGAAGAGTACAAGTACCCTAAAATTGAAAGGTGGTCCCTACACTGAAAA
CGCACATAGTTTGTCAAAAGTGTACAAAAGGGAAAGAGTCTTATTTTAAGCTTTCAGGCTTTCTTAAAAACTTGGGGACCAGAATTTCAA
TGTATGTTTCCATTGTTGAAGATAACATTTTCTTCAAAGAGCCTTAACCTTTTGTACTGGAAGGAAATATTTTCTGGACTTAAGTAGTTG
CCTAAATTTAAGATTCCTACACTTTATTTCTGCCATTGATGCTTTTCCTAAACCCTTATACTATCTTTTTATTATCTGAGCCTTTTCCTA
ATGCAGCTCATAGGTGCTAGCTAGAGCTGCTGCTCAGTATTGAAGACTTTACAAGGAGATTAGAAATCTTTGGAAAACATATGTGATGAA
ATTGAGCTATATGATTTATCAGAGATCTGATTCCAAAGAGCACAGAATACTGTTCTCAGACCATGAAACCAGACAACACATGTATTGGTT
TAAACTCGATAATGACAGGAAAATTCCAAACTAGAGCAGTAAATTCAAATGGTAAGATGAATCCTAGAAGGCCTCTGATTGCAGCATGTT
GACACCAACCTCACGTTACGAACAATTCACAGAGAATTTGCCTTTGTGGCAACTGAAGATGGAAGTCTGGGGGGCACAGACAACCTTATC
AAACAATATAAAAGCCAATATAAATTCTCATAAGCACTATAGAATTTGCAAATTCAGAACATTTTATACCTAAAAGTAATTCTGTCTTTC
CTAAAGTGTTTTTAACATGAAAATTAGTAGGAAGATGTGGTTACTATTTGGAAAGTGTAATGTAACAAAACTCTCTTTTGTTACCACAAA
TTTTGTGAGTTTAGTACTCTACAGATTGCCCCATAAGAGCAGTAGCTTTTGAAACTCATAATTCTCTGAAATAAATGAAAGACATTTAAT
TCAAGGATCAAAAATTGTGGCCATCTTTGCAAATGACTACCTATAGCCTGTGAAAATACATTTCAAAAAATGTTATGTGCAATGAACACT
AAATTTAAGAGCAGTTACAGTGTGACTCACTCATGTTTAAAAAAAATCGAAGAGCTAAAAAATACGTCTAATTTATGTAACCCATTGGAA
TGTATTTCTAGGTTCTCTTCAGGATTAATTAAATAAACATGCAATTTATGAAAACATATAAACAATTATTTATCACTTTTATGACCCAAA
TCACAATAAAATTGTCATTTAGGATAAACTGGGGAGAATAGACTGAACATATGGTTATATTCACAGTTATTTATTAACTTAAATGTTATT
CCAACATTAGAGCTAATGTTAAAAAGATTTAAACTGTAACGTCTAATATTTGGAATAATATATTAAAGTATTAGCACTGTGGTTGATTTT

>87129_87129_5_STAMBP-AQP4_STAMBP_chr2_74058186_ENST00000536064_AQP4_chr18_24442560_ENST00000383168_length(amino acids)=428AA_BP=116
MDFEGDRPPCCIPFLELLNQVVTGAASWPWEVVPFLTHKNLSQENLVLMSDHGDVSLPPEDRVRALSQLGSAVEVNEDIPPRRYFRSGVE
IIRMASIYSEEGNIEHAFILYNKYITKCGPLCTRENIMVAFKGVWTQAFWKAVTAEFLAMLIFVLLSLGSTINWGGTEKPLPVDMVLISL
CFGLSIATMVQCFGHISGGHINPAVTVAMVCTRKISIAKSVFYIAAQCLGAIIGAGILYLVTPPSVVGGLGVTMVHGNLTAGHGLLVELI
ITFQLVFTIFASCDSKRTDVTGSIALAIGFSVAIGHLFAINYTGASMNPARSFGPAVIMGNWENHWIYWVGPIIGAVLAGGLYEYVFCPD

--------------------------------------------------------------

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Fusion Gene PPI Analysis for STAMBP-AQP4


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with
HgeneSTAMBPchr2:74058186chr18:24442560ENST00000339566+2101_12767.66666666666667425.0CHMP3
HgeneSTAMBPchr2:74058186chr18:24442560ENST00000394070+2101_12767.66666666666667425.0CHMP3
HgeneSTAMBPchr2:74058186chr18:24442560ENST00000394073+3111_12767.66666666666667425.0CHMP3
HgeneSTAMBPchr2:74058186chr18:24442560ENST00000409707+2111_12767.66666666666667507.3333333333333CHMP3
HgeneSTAMBPchr2:74058186chr18:24442560ENST00000339566+210227_23167.66666666666667425.0STAM
HgeneSTAMBPchr2:74058186chr18:24442560ENST00000394070+210227_23167.66666666666667425.0STAM
HgeneSTAMBPchr2:74058186chr18:24442560ENST00000394073+311227_23167.66666666666667425.0STAM
HgeneSTAMBPchr2:74058186chr18:24442560ENST00000409707+211227_23167.66666666666667507.3333333333333STAM


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for STAMBP-AQP4


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for STAMBP-AQP4


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource