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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:STARD10-HOMER3 (FusionGDB2 ID:87151)

Fusion Gene Summary for STARD10-HOMER3

check button Fusion gene summary
Fusion gene informationFusion gene name: STARD10-HOMER3
Fusion gene ID: 87151
HgeneTgene
Gene symbol

STARD10

HOMER3

Gene ID

10809

9454

Gene nameStAR related lipid transfer domain containing 10homer scaffold protein 3
SynonymsCGI-52|NY-CO-28|PCTP2|SDCCAG28HOMER-3|VESL3
Cytomap

11q13.4

19p13.11

Type of geneprotein-codingprotein-coding
DescriptionSTART domain-containing protein 10PCTP-LPCTP-like proteinSTART domain containing 10StAR-related lipid transfer (START) domain containing 10antigen NY-CO-28serologically defined colon cancer antigen 28stAR-related lipid transfer protein 10homer protein homolog 3Homer, neuronal immediate early gene, 3homer homolog 3homer scaffolding protein 3
Modification date2020031320200327
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000545082, ENST00000334805, 
ENST00000538437, ENST00000538536, 
ENST00000543304, 		ENST00000221222, 
ENST00000433218, ENST00000539827, 
ENST00000542541, ENST00000355887, 
ENST00000392351, ENST00000594439, 
ENST00000594794, 
Fusion gene scores* DoF score10 X 7 X 6=4203 X 3 X 3=27
# samples 103
** MAII scorelog2(10/420*10)=-2.0703893278914
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(3/27*10)=0.15200309344505
effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs).
DoF>8 and MAII>0
Context

PubMed: STARD10 [Title/Abstract] AND HOMER3 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointSTARD10(72492103)-HOMER3(19040294), # samples:1
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check buttonFusion gene breakpoints across STARD10 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across HOMER3 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4BRCATCGA-A2-A0CW-01ASTARD10chr11

72492103

-HOMER3chr19

19040294

-


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Fusion Gene ORF analysis for STARD10-HOMER3

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
Frame-shiftENST00000545082ENST00000221222STARD10chr11

72492103

-HOMER3chr19

19040294

-
Frame-shiftENST00000545082ENST00000433218STARD10chr11

72492103

-HOMER3chr19

19040294

-
Frame-shiftENST00000545082ENST00000539827STARD10chr11

72492103

-HOMER3chr19

19040294

-
Frame-shiftENST00000545082ENST00000542541STARD10chr11

72492103

-HOMER3chr19

19040294

-
In-frameENST00000545082ENST00000355887STARD10chr11

72492103

-HOMER3chr19

19040294

-
In-frameENST00000545082ENST00000392351STARD10chr11

72492103

-HOMER3chr19

19040294

-
In-frameENST00000545082ENST00000594439STARD10chr11

72492103

-HOMER3chr19

19040294

-
In-frameENST00000545082ENST00000594794STARD10chr11

72492103

-HOMER3chr19

19040294

-
intron-3CDSENST00000334805ENST00000221222STARD10chr11

72492103

-HOMER3chr19

19040294

-
intron-3CDSENST00000334805ENST00000355887STARD10chr11

72492103

-HOMER3chr19

19040294

-
intron-3CDSENST00000334805ENST00000392351STARD10chr11

72492103

-HOMER3chr19

19040294

-
intron-3CDSENST00000334805ENST00000433218STARD10chr11

72492103

-HOMER3chr19

19040294

-
intron-3CDSENST00000334805ENST00000539827STARD10chr11

72492103

-HOMER3chr19

19040294

-
intron-3CDSENST00000334805ENST00000542541STARD10chr11

72492103

-HOMER3chr19

19040294

-
intron-3CDSENST00000334805ENST00000594439STARD10chr11

72492103

-HOMER3chr19

19040294

-
intron-3CDSENST00000334805ENST00000594794STARD10chr11

72492103

-HOMER3chr19

19040294

-
intron-3CDSENST00000538437ENST00000221222STARD10chr11

72492103

-HOMER3chr19

19040294

-
intron-3CDSENST00000538437ENST00000355887STARD10chr11

72492103

-HOMER3chr19

19040294

-
intron-3CDSENST00000538437ENST00000392351STARD10chr11

72492103

-HOMER3chr19

19040294

-
intron-3CDSENST00000538437ENST00000433218STARD10chr11

72492103

-HOMER3chr19

19040294

-
intron-3CDSENST00000538437ENST00000539827STARD10chr11

72492103

-HOMER3chr19

19040294

-
intron-3CDSENST00000538437ENST00000542541STARD10chr11

72492103

-HOMER3chr19

19040294

-
intron-3CDSENST00000538437ENST00000594439STARD10chr11

72492103

-HOMER3chr19

19040294

-
intron-3CDSENST00000538437ENST00000594794STARD10chr11

72492103

-HOMER3chr19

19040294

-
intron-3CDSENST00000538536ENST00000221222STARD10chr11

72492103

-HOMER3chr19

19040294

-
intron-3CDSENST00000538536ENST00000355887STARD10chr11

72492103

-HOMER3chr19

19040294

-
intron-3CDSENST00000538536ENST00000392351STARD10chr11

72492103

-HOMER3chr19

19040294

-
intron-3CDSENST00000538536ENST00000433218STARD10chr11

72492103

-HOMER3chr19

19040294

-
intron-3CDSENST00000538536ENST00000539827STARD10chr11

72492103

-HOMER3chr19

19040294

-
intron-3CDSENST00000538536ENST00000542541STARD10chr11

72492103

-HOMER3chr19

19040294

-
intron-3CDSENST00000538536ENST00000594439STARD10chr11

72492103

-HOMER3chr19

19040294

-
intron-3CDSENST00000538536ENST00000594794STARD10chr11

72492103

-HOMER3chr19

19040294

-
intron-3CDSENST00000543304ENST00000221222STARD10chr11

72492103

-HOMER3chr19

19040294

-
intron-3CDSENST00000543304ENST00000355887STARD10chr11

72492103

-HOMER3chr19

19040294

-
intron-3CDSENST00000543304ENST00000392351STARD10chr11

72492103

-HOMER3chr19

19040294

-
intron-3CDSENST00000543304ENST00000433218STARD10chr11

72492103

-HOMER3chr19

19040294

-
intron-3CDSENST00000543304ENST00000539827STARD10chr11

72492103

-HOMER3chr19

19040294

-
intron-3CDSENST00000543304ENST00000542541STARD10chr11

72492103

-HOMER3chr19

19040294

-
intron-3CDSENST00000543304ENST00000594439STARD10chr11

72492103

-HOMER3chr19

19040294

-
intron-3CDSENST00000543304ENST00000594794STARD10chr11

72492103

-HOMER3chr19

19040294

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000545082STARD10chr1172492103-ENST00000392351HOMER3chr1919040294-69541237420127
ENST00000545082STARD10chr1172492103-ENST00000594794HOMER3chr1919040294-69241237420127
ENST00000545082STARD10chr1172492103-ENST00000594439HOMER3chr1919040294-4594123860129
ENST00000545082STARD10chr1172492103-ENST00000355887HOMER3chr1919040294-45541237420127

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000545082ENST00000392351STARD10chr1172492103-HOMER3chr1919040294-0.63903430.36096573
ENST00000545082ENST00000594794STARD10chr1172492103-HOMER3chr1919040294-0.62180940.37819055
ENST00000545082ENST00000594439STARD10chr1172492103-HOMER3chr1919040294-0.70593470.29406524
ENST00000545082ENST00000355887STARD10chr1172492103-HOMER3chr1919040294-0.70462830.2953717

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Fusion Genomic Features for STARD10-HOMER3


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for STARD10-HOMER3


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr11:72492103/chr19:19040294)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneHOMER3chr11:72492103chr19:19040294ENST0000022122209191_2430359.0Coiled coilOntology_term=ECO:0000255
TgeneHOMER3chr11:72492103chr19:19040294ENST0000022122209254_3580359.0Coiled coilOntology_term=ECO:0000255
TgeneHOMER3chr11:72492103chr19:19040294ENST00000355887010191_2430359.0Coiled coilOntology_term=ECO:0000255
TgeneHOMER3chr11:72492103chr19:19040294ENST00000355887010254_3580359.0Coiled coilOntology_term=ECO:0000255
TgeneHOMER3chr11:72492103chr19:19040294ENST00000392351010191_2430362.0Coiled coilOntology_term=ECO:0000255
TgeneHOMER3chr11:72492103chr19:19040294ENST00000392351010254_3580362.0Coiled coilOntology_term=ECO:0000255
TgeneHOMER3chr11:72492103chr19:19040294ENST00000433218010191_2430359.0Coiled coilOntology_term=ECO:0000255
TgeneHOMER3chr11:72492103chr19:19040294ENST00000433218010254_3580359.0Coiled coilOntology_term=ECO:0000255
TgeneHOMER3chr11:72492103chr19:19040294ENST0000053982709191_2430362.0Coiled coilOntology_term=ECO:0000255
TgeneHOMER3chr11:72492103chr19:19040294ENST0000053982709254_3580362.0Coiled coilOntology_term=ECO:0000255
TgeneHOMER3chr11:72492103chr19:19040294ENST00000542541010191_2430362.0Coiled coilOntology_term=ECO:0000255
TgeneHOMER3chr11:72492103chr19:19040294ENST00000542541010254_3580362.0Coiled coilOntology_term=ECO:0000255
TgeneHOMER3chr11:72492103chr19:19040294ENST0000059443908191_2430326.0Coiled coilOntology_term=ECO:0000255
TgeneHOMER3chr11:72492103chr19:19040294ENST0000059443908254_3580326.0Coiled coilOntology_term=ECO:0000255
TgeneHOMER3chr11:72492103chr19:19040294ENST0000022122209206_2110359.0Compositional biasNote=Poly-Ala
TgeneHOMER3chr11:72492103chr19:19040294ENST00000355887010206_2110359.0Compositional biasNote=Poly-Ala
TgeneHOMER3chr11:72492103chr19:19040294ENST00000392351010206_2110362.0Compositional biasNote=Poly-Ala
TgeneHOMER3chr11:72492103chr19:19040294ENST00000433218010206_2110359.0Compositional biasNote=Poly-Ala
TgeneHOMER3chr11:72492103chr19:19040294ENST0000053982709206_2110362.0Compositional biasNote=Poly-Ala
TgeneHOMER3chr11:72492103chr19:19040294ENST00000542541010206_2110362.0Compositional biasNote=Poly-Ala
TgeneHOMER3chr11:72492103chr19:19040294ENST0000059443908206_2110326.0Compositional biasNote=Poly-Ala
TgeneHOMER3chr11:72492103chr19:19040294ENST00000221222091_1130359.0DomainWH1
TgeneHOMER3chr11:72492103chr19:19040294ENST000003558870101_1130359.0DomainWH1
TgeneHOMER3chr11:72492103chr19:19040294ENST000003923510101_1130362.0DomainWH1
TgeneHOMER3chr11:72492103chr19:19040294ENST000004332180101_1130359.0DomainWH1
TgeneHOMER3chr11:72492103chr19:19040294ENST00000539827091_1130362.0DomainWH1
TgeneHOMER3chr11:72492103chr19:19040294ENST000005425410101_1130362.0DomainWH1
TgeneHOMER3chr11:72492103chr19:19040294ENST00000594439081_1130326.0DomainWH1

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneSTARD10chr11:72492103chr19:19040294ENST00000334805-1714_2240292.0DomainSTART
HgeneSTARD10chr11:72492103chr19:19040294ENST00000543304-1814_2240292.0DomainSTART


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Fusion Gene Sequence for STARD10-HOMER3


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>87151_87151_1_STARD10-HOMER3_STARD10_chr11_72492103_ENST00000545082_HOMER3_chr19_19040294_ENST00000355887_length(transcript)=455nt_BP=412nt
CCCGAGCCCCCAGCCTAGCCGGGAGGGGCGCGCGGGGCTGGGGCCCGGGGCGGGGCCGGGCGGCGGGACCCACTGCTCCTCCCACCAGAG
CCCCCGCGCGGCCCCGGGTCTCCCGGGCAGCTGCGGCGGCGGCGCTGGCACCCCGGCCCCGGCGGGCCCCGGCGGAGCGGCGGGCAAAGG
TCCCAGGAAGGTGGCGTCAGCATCTGCAGCCGCGTCGACGTTGTCGGAGCCTCCGCGGAGGACCCAGGAGAGCCGGACTAGGACCAGGGC
CCTGGGCCTCCCCACACTCCCCATGGAGAAGCTGGCGGCCTCTACAGAGCCCCAAGGGCCTCGGCCGGTCCTGGGCCGTGAGAGTGTCCA
GGTGCCCGATGACCAAGACTTTCGCAGCTTCCGGTCAGAGTGTGAGGCTGAGGCTGCGTGAGGGCCTGGCCCGCCTGGCTGAGGCTGCGC

>87151_87151_1_STARD10-HOMER3_STARD10_chr11_72492103_ENST00000545082_HOMER3_chr19_19040294_ENST00000355887_length(amino acids)=127AA_BP=
MGPGAGPGGGTHCSSHQSPRAAPGLPGSCGGGAGTPAPAGPGGAAGKGPRKVASASAAASTLSEPPRRTQESRTRTRALGLPTLPMEKLA

--------------------------------------------------------------
>87151_87151_2_STARD10-HOMER3_STARD10_chr11_72492103_ENST00000545082_HOMER3_chr19_19040294_ENST00000392351_length(transcript)=695nt_BP=412nt
CCCGAGCCCCCAGCCTAGCCGGGAGGGGCGCGCGGGGCTGGGGCCCGGGGCGGGGCCGGGCGGCGGGACCCACTGCTCCTCCCACCAGAG
CCCCCGCGCGGCCCCGGGTCTCCCGGGCAGCTGCGGCGGCGGCGCTGGCACCCCGGCCCCGGCGGGCCCCGGCGGAGCGGCGGGCAAAGG
TCCCAGGAAGGTGGCGTCAGCATCTGCAGCCGCGTCGACGTTGTCGGAGCCTCCGCGGAGGACCCAGGAGAGCCGGACTAGGACCAGGGC
CCTGGGCCTCCCCACACTCCCCATGGAGAAGCTGGCGGCCTCTACAGAGCCCCAAGGGCCTCGGCCGGTCCTGGGCCGTGAGAGTGTCCA
GGTGCCCGATGACCAAGACTTTCGCAGCTTCCGGTCAGAGTGTGAGGCTGAGGCTGCGTGAGGGCCTGGCCCGCCTGGCTGAGGCTGCGC
CCTGAGCCGGGGCTGGTTTTCTATGAACGATTCCGGCCTGGGATGCGGGCCAGGCTGCAGGCGGCATAGTTGGGCCCATTCGTCCTGGAA
AGGGACTGGGGGGTCCCAACTTAGCCCTGGGTGGGCCGGGCCGGGCTGGGCTGGGGTGGGCCCCAGTCGGCTCTGGTTGTTGGCAGCTTT

>87151_87151_2_STARD10-HOMER3_STARD10_chr11_72492103_ENST00000545082_HOMER3_chr19_19040294_ENST00000392351_length(amino acids)=127AA_BP=
MGPGAGPGGGTHCSSHQSPRAAPGLPGSCGGGAGTPAPAGPGGAAGKGPRKVASASAAASTLSEPPRRTQESRTRTRALGLPTLPMEKLA

--------------------------------------------------------------
>87151_87151_3_STARD10-HOMER3_STARD10_chr11_72492103_ENST00000545082_HOMER3_chr19_19040294_ENST00000594439_length(transcript)=459nt_BP=412nt
CCCGAGCCCCCAGCCTAGCCGGGAGGGGCGCGCGGGGCTGGGGCCCGGGGCGGGGCCGGGCGGCGGGACCCACTGCTCCTCCCACCAGAG
CCCCCGCGCGGCCCCGGGTCTCCCGGGCAGCTGCGGCGGCGGCGCTGGCACCCCGGCCCCGGCGGGCCCCGGCGGAGCGGCGGGCAAAGG
TCCCAGGAAGGTGGCGTCAGCATCTGCAGCCGCGTCGACGTTGTCGGAGCCTCCGCGGAGGACCCAGGAGAGCCGGACTAGGACCAGGGC
CCTGGGCCTCCCCACACTCCCCATGGAGAAGCTGGCGGCCTCTACAGAGCCCCAAGGGCCTCGGCCGGTCCTGGGCCGTGAGAGTGTCCA
GGTGCCCGATGACCAAGACTTTCGCAGCTTCCGGTCAGAGTGTGAGGCTGAGGCTGCGTGAGGGCCTGGCCCGCCTGGCTGAGGCTGCGC

>87151_87151_3_STARD10-HOMER3_STARD10_chr11_72492103_ENST00000545082_HOMER3_chr19_19040294_ENST00000594439_length(amino acids)=129AA_BP=
MRKSWSSGTWTLSRPRTGRGPWGSVEAASFSMGSVGRPRALVLVRLSWVLRGGSDNVDAAADADATFLGPLPAAPPGPAGAGVPAPPPQL

--------------------------------------------------------------
>87151_87151_4_STARD10-HOMER3_STARD10_chr11_72492103_ENST00000545082_HOMER3_chr19_19040294_ENST00000594794_length(transcript)=692nt_BP=412nt
CCCGAGCCCCCAGCCTAGCCGGGAGGGGCGCGCGGGGCTGGGGCCCGGGGCGGGGCCGGGCGGCGGGACCCACTGCTCCTCCCACCAGAG
CCCCCGCGCGGCCCCGGGTCTCCCGGGCAGCTGCGGCGGCGGCGCTGGCACCCCGGCCCCGGCGGGCCCCGGCGGAGCGGCGGGCAAAGG
TCCCAGGAAGGTGGCGTCAGCATCTGCAGCCGCGTCGACGTTGTCGGAGCCTCCGCGGAGGACCCAGGAGAGCCGGACTAGGACCAGGGC
CCTGGGCCTCCCCACACTCCCCATGGAGAAGCTGGCGGCCTCTACAGAGCCCCAAGGGCCTCGGCCGGTCCTGGGCCGTGAGAGTGTCCA
GGTGCCCGATGACCAAGACTTTCGCAGCTTCCGGTCAGAGTGTGAGGCTGAGGCTGCGTGAGGGCCTGGCCCGCCTGGCTGAGGCTGCGC
CCTGAGCCGGGGCTGGTTTTCTATGAACGATTCCGGCCTGGGATGCGGGCCAGGCTGCAGGCGGCATAGTTGGGCCCATTCGTCCTGGAA
AGGGACTGGGGGGTCCCAACTTAGCCCTGGGTGGGCCGGGCCGGGCTGGGCTGGGGTGGGCCCCAGTCGGCTCTGGTTGTTGGCAGCTTT

>87151_87151_4_STARD10-HOMER3_STARD10_chr11_72492103_ENST00000545082_HOMER3_chr19_19040294_ENST00000594794_length(amino acids)=127AA_BP=
MGPGAGPGGGTHCSSHQSPRAAPGLPGSCGGGAGTPAPAGPGGAAGKGPRKVASASAAASTLSEPPRRTQESRTRTRALGLPTLPMEKLA

--------------------------------------------------------------

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Fusion Gene PPI Analysis for STARD10-HOMER3


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for STARD10-HOMER3


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for STARD10-HOMER3


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource