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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:STAT3-C1orf43 (FusionGDB2 ID:87239)

Fusion Gene Summary for STAT3-C1orf43

check button Fusion gene summary
Fusion gene informationFusion gene name: STAT3-C1orf43
Fusion gene ID: 87239
HgeneTgene
Gene symbol

STAT3

C1orf43

Gene ID

6774

25912

Gene namesignal transducer and activator of transcription 3chromosome 1 open reading frame 43
SynonymsADMIO|ADMIO1|APRF|HIESHSPC012|NICE-3|NICE3|NS5ATP4|S863-3
Cytomap

17q21.2

1q21.3

Type of geneprotein-codingprotein-coding
Descriptionsignal transducer and activator of transcription 3DNA-binding protein APRFacute-phase response factoruncharacterized protein C1orf43HCV NS5A-transactivated protein 4hepatitis C virus NS5A-transactivated protein 4
Modification date2020032920200327
UniProtAcc.

Q9BWL3

Ensembl transtripts involved in fusion geneENST00000264657, ENST00000389272, 
ENST00000404395, ENST00000585517, 
ENST00000588969, ENST00000590776, 
ENST00000483282, ENST00000368516, 
ENST00000368518, ENST00000350592, 
ENST00000362076, ENST00000368519, 
ENST00000368521, 
Fusion gene scores* DoF score18 X 20 X 10=36005 X 5 X 4=100
# samples 235
** MAII scorelog2(23/3600*10)=-3.96829114027266
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(5/100*10)=-1
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: STAT3 [Title/Abstract] AND C1orf43 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointSTAT3(40497577)-C1orf43(154180124), # samples:2
Anticipated loss of major functional domain due to fusion event.STAT3-C1orf43 seems lost the major protein functional domain in Hgene partner, which is a CGC due to the frame-shifted ORF.
STAT3-C1orf43 seems lost the major protein functional domain in Hgene partner, which is a IUPHAR drug target due to the frame-shifted ORF.
STAT3-C1orf43 seems lost the major protein functional domain in Hgene partner, which is a transcription factor due to the frame-shifted ORF.
STAT3-C1orf43 seems lost the major protein functional domain in Hgene partner, which is a tumor suppressor due to the frame-shifted ORF.
STAT3-C1orf43 seems lost the major protein functional domain in Tgene partner, which is a essential gene due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneSTAT3

GO:0006355

regulation of transcription, DNA-templated

15664994|17344214

HgeneSTAT3

GO:0006606

protein import into nucleus

18234692

HgeneSTAT3

GO:0010507

negative regulation of autophagy

26962683

HgeneSTAT3

GO:0010628

positive regulation of gene expression

23820254

HgeneSTAT3

GO:0030522

intracellular receptor signaling pathway

17324931

HgeneSTAT3

GO:0032355

response to estradiol

12552091

HgeneSTAT3

GO:0032870

cellular response to hormone stimulus

12552091

HgeneSTAT3

GO:0033210

leptin-mediated signaling pathway

17344214

HgeneSTAT3

GO:0035278

miRNA mediated inhibition of translation

23820254

HgeneSTAT3

GO:0044320

cellular response to leptin stimulus

17344214

HgeneSTAT3

GO:0044321

response to leptin

17344214

HgeneSTAT3

GO:0045893

positive regulation of transcription, DNA-templated

19390056

HgeneSTAT3

GO:0045944

positive regulation of transcription by RNA polymerase II

17324931|27050391|31462771

HgeneSTAT3

GO:0051726

regulation of cell cycle

17344214

HgeneSTAT3

GO:0060396

growth hormone receptor signaling pathway

10925297

HgeneSTAT3

GO:0060397

JAK-STAT cascade involved in growth hormone signaling pathway

12552091

HgeneSTAT3

GO:0070102

interleukin-6-mediated signaling pathway

12359225|12552091|17324931|24429361

HgeneSTAT3

GO:1902895

positive regulation of pri-miRNA transcription by RNA polymerase II

19390056|23820254

HgeneSTAT3

GO:2000637

positive regulation of gene silencing by miRNA

23820254


check buttonFusion gene breakpoints across STAT3 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across C1orf43 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4LIHCTCGA-G3-A7M7-01ASTAT3chr17

40497577

-C1orf43chr1

154180124

-


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Fusion Gene ORF analysis for STAT3-C1orf43

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-5UTRENST00000264657ENST00000483282STAT3chr17

40497577

-C1orf43chr1

154180124

-
5CDS-5UTRENST00000389272ENST00000483282STAT3chr17

40497577

-C1orf43chr1

154180124

-
5CDS-5UTRENST00000404395ENST00000483282STAT3chr17

40497577

-C1orf43chr1

154180124

-
5CDS-5UTRENST00000585517ENST00000483282STAT3chr17

40497577

-C1orf43chr1

154180124

-
5CDS-5UTRENST00000588969ENST00000483282STAT3chr17

40497577

-C1orf43chr1

154180124

-
5CDS-intronENST00000264657ENST00000368516STAT3chr17

40497577

-C1orf43chr1

154180124

-
5CDS-intronENST00000264657ENST00000368518STAT3chr17

40497577

-C1orf43chr1

154180124

-
5CDS-intronENST00000389272ENST00000368516STAT3chr17

40497577

-C1orf43chr1

154180124

-
5CDS-intronENST00000389272ENST00000368518STAT3chr17

40497577

-C1orf43chr1

154180124

-
5CDS-intronENST00000404395ENST00000368516STAT3chr17

40497577

-C1orf43chr1

154180124

-
5CDS-intronENST00000404395ENST00000368518STAT3chr17

40497577

-C1orf43chr1

154180124

-
5CDS-intronENST00000585517ENST00000368516STAT3chr17

40497577

-C1orf43chr1

154180124

-
5CDS-intronENST00000585517ENST00000368518STAT3chr17

40497577

-C1orf43chr1

154180124

-
5CDS-intronENST00000588969ENST00000368516STAT3chr17

40497577

-C1orf43chr1

154180124

-
5CDS-intronENST00000588969ENST00000368518STAT3chr17

40497577

-C1orf43chr1

154180124

-
Frame-shiftENST00000264657ENST00000350592STAT3chr17

40497577

-C1orf43chr1

154180124

-
Frame-shiftENST00000264657ENST00000362076STAT3chr17

40497577

-C1orf43chr1

154180124

-
Frame-shiftENST00000264657ENST00000368519STAT3chr17

40497577

-C1orf43chr1

154180124

-
Frame-shiftENST00000264657ENST00000368521STAT3chr17

40497577

-C1orf43chr1

154180124

-
Frame-shiftENST00000389272ENST00000362076STAT3chr17

40497577

-C1orf43chr1

154180124

-
Frame-shiftENST00000404395ENST00000362076STAT3chr17

40497577

-C1orf43chr1

154180124

-
Frame-shiftENST00000585517ENST00000362076STAT3chr17

40497577

-C1orf43chr1

154180124

-
Frame-shiftENST00000588969ENST00000362076STAT3chr17

40497577

-C1orf43chr1

154180124

-
In-frameENST00000389272ENST00000350592STAT3chr17

40497577

-C1orf43chr1

154180124

-
In-frameENST00000389272ENST00000368519STAT3chr17

40497577

-C1orf43chr1

154180124

-
In-frameENST00000389272ENST00000368521STAT3chr17

40497577

-C1orf43chr1

154180124

-
In-frameENST00000404395ENST00000350592STAT3chr17

40497577

-C1orf43chr1

154180124

-
In-frameENST00000404395ENST00000368519STAT3chr17

40497577

-C1orf43chr1

154180124

-
In-frameENST00000404395ENST00000368521STAT3chr17

40497577

-C1orf43chr1

154180124

-
In-frameENST00000585517ENST00000350592STAT3chr17

40497577

-C1orf43chr1

154180124

-
In-frameENST00000585517ENST00000368519STAT3chr17

40497577

-C1orf43chr1

154180124

-
In-frameENST00000585517ENST00000368521STAT3chr17

40497577

-C1orf43chr1

154180124

-
In-frameENST00000588969ENST00000350592STAT3chr17

40497577

-C1orf43chr1

154180124

-
In-frameENST00000588969ENST00000368519STAT3chr17

40497577

-C1orf43chr1

154180124

-
In-frameENST00000588969ENST00000368521STAT3chr17

40497577

-C1orf43chr1

154180124

-
intron-3CDSENST00000590776ENST00000350592STAT3chr17

40497577

-C1orf43chr1

154180124

-
intron-3CDSENST00000590776ENST00000362076STAT3chr17

40497577

-C1orf43chr1

154180124

-
intron-3CDSENST00000590776ENST00000368519STAT3chr17

40497577

-C1orf43chr1

154180124

-
intron-3CDSENST00000590776ENST00000368521STAT3chr17

40497577

-C1orf43chr1

154180124

-
intron-5UTRENST00000590776ENST00000483282STAT3chr17

40497577

-C1orf43chr1

154180124

-
intron-intronENST00000590776ENST00000368516STAT3chr17

40497577

-C1orf43chr1

154180124

-
intron-intronENST00000590776ENST00000368518STAT3chr17

40497577

-C1orf43chr1

154180124

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000585517STAT3chr1740497577-ENST00000368521C1orf43chr1154180124-1480537193732179
ENST00000585517STAT3chr1740497577-ENST00000350592C1orf43chr1154180124-1466537193732179
ENST00000585517STAT3chr1740497577-ENST00000368519C1orf43chr1154180124-1010537193732179
ENST00000389272STAT3chr1740497577-ENST00000368521C1orf43chr1154180124-1340397158592144
ENST00000389272STAT3chr1740497577-ENST00000350592C1orf43chr1154180124-1326397158592144
ENST00000389272STAT3chr1740497577-ENST00000368519C1orf43chr1154180124-870397158592144
ENST00000588969STAT3chr1740497577-ENST00000368521C1orf43chr1154180124-152057713582189
ENST00000588969STAT3chr1740497577-ENST00000350592C1orf43chr1154180124-150657713582189
ENST00000588969STAT3chr1740497577-ENST00000368519C1orf43chr1154180124-105057713582189
ENST00000404395STAT3chr1740497577-ENST00000368521C1orf43chr1154180124-1452509165704179
ENST00000404395STAT3chr1740497577-ENST00000350592C1orf43chr1154180124-1438509165704179
ENST00000404395STAT3chr1740497577-ENST00000368519C1orf43chr1154180124-982509165704179

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000585517ENST00000368521STAT3chr1740497577-C1orf43chr1154180124-0.301788270.6982118
ENST00000585517ENST00000350592STAT3chr1740497577-C1orf43chr1154180124-0.32780770.67219234
ENST00000585517ENST00000368519STAT3chr1740497577-C1orf43chr1154180124-0.119558460.8804416
ENST00000389272ENST00000368521STAT3chr1740497577-C1orf43chr1154180124-0.235829160.7641708
ENST00000389272ENST00000350592STAT3chr1740497577-C1orf43chr1154180124-0.26432850.73567146
ENST00000389272ENST00000368519STAT3chr1740497577-C1orf43chr1154180124-0.07162360.92837644
ENST00000588969ENST00000368521STAT3chr1740497577-C1orf43chr1154180124-0.232230810.7677692
ENST00000588969ENST00000350592STAT3chr1740497577-C1orf43chr1154180124-0.26223740.7377626
ENST00000588969ENST00000368519STAT3chr1740497577-C1orf43chr1154180124-0.122364210.8776358
ENST00000404395ENST00000368521STAT3chr1740497577-C1orf43chr1154180124-0.318335680.68166435
ENST00000404395ENST00000350592STAT3chr1740497577-C1orf43chr1154180124-0.34915970.65084034
ENST00000404395ENST00000368519STAT3chr1740497577-C1orf43chr1154180124-0.153803910.8461961

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Fusion Genomic Features for STAT3-C1orf43


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for STAT3-C1orf43


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr17:40497577/chr1:154180124)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
.C1orf43

Q9BWL3

FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: General regulator of phagocytosis. Required to uptake Gram negative bacterium by macrophages. {ECO:0000269|PubMed:31540829}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneC1orf43chr17:40497577chr1:154180124ENST000003685180611_310190.0TransmembraneHelical

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneSTAT3chr17:40497577chr1:154180124ENST00000264657-424580_670124771.0DomainSH2
HgeneSTAT3chr17:40497577chr1:154180124ENST00000404395-424580_670124770.0DomainSH2
HgeneSTAT3chr17:40497577chr1:154180124ENST00000588969-424580_670124771.0DomainSH2
HgeneSTAT3chr17:40497577chr1:154180124ENST00000264657-424150_162124771.0MotifNote=Essential for nuclear import
HgeneSTAT3chr17:40497577chr1:154180124ENST00000404395-424150_162124770.0MotifNote=Essential for nuclear import
HgeneSTAT3chr17:40497577chr1:154180124ENST00000588969-424150_162124771.0MotifNote=Essential for nuclear import
TgeneC1orf43chr17:40497577chr1:154180124ENST000003505924611_31154220.0TransmembraneHelical
TgeneC1orf43chr17:40497577chr1:154180124ENST000003620763511_31136202.0TransmembraneHelical
TgeneC1orf43chr17:40497577chr1:154180124ENST000003685215711_31188254.0TransmembraneHelical


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Fusion Gene Sequence for STAT3-C1orf43


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>87239_87239_1_STAT3-C1orf43_STAT3_chr17_40497577_ENST00000389272_C1orf43_chr1_154180124_ENST00000350592_length(transcript)=1326nt_BP=397nt
GGGAACAAGCCCCAACCGGATCCTGGACAGGCACCCCGGCTTGGCGCTGTCTCTCCCCCTCGGCTCGGAGAGGCCCTTCGGCCTGAGGGA
GCCTCGCCGCCCGTCCCCGGCACACGCGCAGCCCCGGCCTCTCGGCCTCTGCCGGAGAAACAGGGCATATGCGGCCAGCAAAGAATCACA
TGCCACTTTGGTGTTTCATAATCTCCTGGGAGAGATTGACCAGCAGTATAGCCGCTTCCTGCAAGAGTCGAATGTTCTCTATCAGCACAA
TCTACGAAGAATCAAGCAGTTTCTTCAGAGCAGGTATCTTGAGAAGCCAATGGAGATTGCCCGGATTGTGGCCCGGTGCCTGTGGGAAGA
ATCACGCCTTCTACAGACTGCAGCCACTGCGGCCCAGGGTTAAAGCACGAATTGGGAGCTCTCAGCGACATCACCAGTCAGCAGCCAAAG
ACCTAACTCAGTCCCCTGAGGTCTCCCCAACAACCATCCAGGTGACATACCTCCCCTCCAGTCAGAAGAGTAAACGTGCCAAGCACTTCC
TTGAATTGAAGAGCTTTAAGGATAACTATAACACATTGGAGAGTACTCTGTGACGGAGCTGAAGGACTCTTGCCGTAGATTAAGCCAGTC
AGTTGCAATGTGCAAGACAGGCTGCTTGCCGGGCCGCCCTCGGAACATCTGGCCCAGCAGGCCCAGACTGTATCCATCCAAGTTCCCGTT
GTATCCAGAGTTCTTAGAGCTTGTGTCTAAAGGGTAATTCCCCAACCCTTCCTTATGAGCATTTTTAGAACATTGGCTAAGACTATTTTC
CCCCAGTAGCGCTTTTTTCTGGATTTGCATTCAGGTGTTATTCTTAATGTTTCTGTCAAAGCTTCTTAAAAATCTTCACTTGGTTTCAGC
CATAGTTCACCTTCCCTGTTCCAGGTTTATTTAATTCCAAAGGTGAGAGTTGGAGTGAGATGTCTTCCATATCTATACCTTTGTGCACAG
TTGAATGGGAACTGTTTGGGTTTAGGGCATCTTAGAGTTGATTGATGGAAAAAGCAGACAGGAACTGGTGGGAGGTCAAGTGGGGAAGTT
GGTGAATGTGGAATAACTTACCTTTGTGCTCCACTTAAACCAGATGTGTTGCAGCTTTCCTGACATGCAAGGATCTACTTTAATTCCACA
CTCTCATTAATAAATTGAATAAAAGGGAATGTTTTGGCACCTGATATAATCTGCCAGGCTATGTGACAGTAGGAAGGAATGGTTTCCCCT

>87239_87239_1_STAT3-C1orf43_STAT3_chr17_40497577_ENST00000389272_C1orf43_chr1_154180124_ENST00000350592_length(amino acids)=144AA_BP=79
MRPAKNHMPLWCFIISWERLTSSIAASCKSRMFSISTIYEESSSFFRAGILRSQWRLPGLWPGACGKNHAFYRLQPLRPRVKARIGSSQR

--------------------------------------------------------------
>87239_87239_2_STAT3-C1orf43_STAT3_chr17_40497577_ENST00000389272_C1orf43_chr1_154180124_ENST00000368519_length(transcript)=870nt_BP=397nt
GGGAACAAGCCCCAACCGGATCCTGGACAGGCACCCCGGCTTGGCGCTGTCTCTCCCCCTCGGCTCGGAGAGGCCCTTCGGCCTGAGGGA
GCCTCGCCGCCCGTCCCCGGCACACGCGCAGCCCCGGCCTCTCGGCCTCTGCCGGAGAAACAGGGCATATGCGGCCAGCAAAGAATCACA
TGCCACTTTGGTGTTTCATAATCTCCTGGGAGAGATTGACCAGCAGTATAGCCGCTTCCTGCAAGAGTCGAATGTTCTCTATCAGCACAA
TCTACGAAGAATCAAGCAGTTTCTTCAGAGCAGGTATCTTGAGAAGCCAATGGAGATTGCCCGGATTGTGGCCCGGTGCCTGTGGGAAGA
ATCACGCCTTCTACAGACTGCAGCCACTGCGGCCCAGGGTTAAAGCACGAATTGGGAGCTCTCAGCGACATCACCAGTCAGCAGCCAAAG
ACCTAACTCAGTCCCCTGAGGTCTCCCCAACAACCATCCAGGTGACATACCTCCCCTCCAGTCAGAAGAGTAAACGTGCCAAGCACTTCC
TTGAATTGAAGAGCTTTAAGGATAACTATAACACATTGGAGAGTACTCTGTGACGGAGCTGAAGGACTCTTGCCGTAGATTAAGCCAGTC
AGTTGCAATGTGCAAGACAGGCTGCTTGCCGGGCCGCCCTCGGAACATCTGGCCCAGCAGGCCCAGACTGTATCCATCCAAGTTCCCGTT
GTATCCAGAGTTCTTAGAGCTTGTGTCTAAAGGGTAATTCCCCAACCCTTCCTTATGAGCATTTTTAGAACATTGGCTAAGACTATTTTC

>87239_87239_2_STAT3-C1orf43_STAT3_chr17_40497577_ENST00000389272_C1orf43_chr1_154180124_ENST00000368519_length(amino acids)=144AA_BP=79
MRPAKNHMPLWCFIISWERLTSSIAASCKSRMFSISTIYEESSSFFRAGILRSQWRLPGLWPGACGKNHAFYRLQPLRPRVKARIGSSQR

--------------------------------------------------------------
>87239_87239_3_STAT3-C1orf43_STAT3_chr17_40497577_ENST00000389272_C1orf43_chr1_154180124_ENST00000368521_length(transcript)=1340nt_BP=397nt
GGGAACAAGCCCCAACCGGATCCTGGACAGGCACCCCGGCTTGGCGCTGTCTCTCCCCCTCGGCTCGGAGAGGCCCTTCGGCCTGAGGGA
GCCTCGCCGCCCGTCCCCGGCACACGCGCAGCCCCGGCCTCTCGGCCTCTGCCGGAGAAACAGGGCATATGCGGCCAGCAAAGAATCACA
TGCCACTTTGGTGTTTCATAATCTCCTGGGAGAGATTGACCAGCAGTATAGCCGCTTCCTGCAAGAGTCGAATGTTCTCTATCAGCACAA
TCTACGAAGAATCAAGCAGTTTCTTCAGAGCAGGTATCTTGAGAAGCCAATGGAGATTGCCCGGATTGTGGCCCGGTGCCTGTGGGAAGA
ATCACGCCTTCTACAGACTGCAGCCACTGCGGCCCAGGGTTAAAGCACGAATTGGGAGCTCTCAGCGACATCACCAGTCAGCAGCCAAAG
ACCTAACTCAGTCCCCTGAGGTCTCCCCAACAACCATCCAGGTGACATACCTCCCCTCCAGTCAGAAGAGTAAACGTGCCAAGCACTTCC
TTGAATTGAAGAGCTTTAAGGATAACTATAACACATTGGAGAGTACTCTGTGACGGAGCTGAAGGACTCTTGCCGTAGATTAAGCCAGTC
AGTTGCAATGTGCAAGACAGGCTGCTTGCCGGGCCGCCCTCGGAACATCTGGCCCAGCAGGCCCAGACTGTATCCATCCAAGTTCCCGTT
GTATCCAGAGTTCTTAGAGCTTGTGTCTAAAGGGTAATTCCCCAACCCTTCCTTATGAGCATTTTTAGAACATTGGCTAAGACTATTTTC
CCCCAGTAGCGCTTTTTTCTGGATTTGCATTCAGGTGTTATTCTTAATGTTTCTGTCAAAGCTTCTTAAAAATCTTCACTTGGTTTCAGC
CATAGTTCACCTTCCCTGTTCCAGGTTTATTTAATTCCAAAGGTGAGAGTTGGAGTGAGATGTCTTCCATATCTATACCTTTGTGCACAG
TTGAATGGGAACTGTTTGGGTTTAGGGCATCTTAGAGTTGATTGATGGAAAAAGCAGACAGGAACTGGTGGGAGGTCAAGTGGGGAAGTT
GGTGAATGTGGAATAACTTACCTTTGTGCTCCACTTAAACCAGATGTGTTGCAGCTTTCCTGACATGCAAGGATCTACTTTAATTCCACA
CTCTCATTAATAAATTGAATAAAAGGGAATGTTTTGGCACCTGATATAATCTGCCAGGCTATGTGACAGTAGGAAGGAATGGTTTCCCCT

>87239_87239_3_STAT3-C1orf43_STAT3_chr17_40497577_ENST00000389272_C1orf43_chr1_154180124_ENST00000368521_length(amino acids)=144AA_BP=79
MRPAKNHMPLWCFIISWERLTSSIAASCKSRMFSISTIYEESSSFFRAGILRSQWRLPGLWPGACGKNHAFYRLQPLRPRVKARIGSSQR

--------------------------------------------------------------
>87239_87239_4_STAT3-C1orf43_STAT3_chr17_40497577_ENST00000404395_C1orf43_chr1_154180124_ENST00000350592_length(transcript)=1438nt_BP=509nt
GGATCCTGGACAGGCACCCCGGCTTGGCGCTGTCTCTCCCCCTCGGCTCGGAGAGGCCCTTCGGCCTGAGGGAGCCTCGCCGCCCGTCCC
CGGCACACGCGCAGCCCCGGCCTCTCGGCCTCTGCCGGAGAAACAGGATGGCCCAATGGAATCAGCTACAGCAGCTTGACACACGGTACC
TGGAGCAGCTCCATCAGCTCTACAGTGACAGCTTCCCAATGGAGCTGCGGCAGTTTCTGGCCCCTTGGATTGAGAGTCAAGATTGGGCAT
ATGCGGCCAGCAAAGAATCACATGCCACTTTGGTGTTTCATAATCTCCTGGGAGAGATTGACCAGCAGTATAGCCGCTTCCTGCAAGAGT
CGAATGTTCTCTATCAGCACAATCTACGAAGAATCAAGCAGTTTCTTCAGAGCAGGTATCTTGAGAAGCCAATGGAGATTGCCCGGATTG
TGGCCCGGTGCCTGTGGGAAGAATCACGCCTTCTACAGACTGCAGCCACTGCGGCCCAGGGTTAAAGCACGAATTGGGAGCTCTCAGCGA
CATCACCAGTCAGCAGCCAAAGACCTAACTCAGTCCCCTGAGGTCTCCCCAACAACCATCCAGGTGACATACCTCCCCTCCAGTCAGAAG
AGTAAACGTGCCAAGCACTTCCTTGAATTGAAGAGCTTTAAGGATAACTATAACACATTGGAGAGTACTCTGTGACGGAGCTGAAGGACT
CTTGCCGTAGATTAAGCCAGTCAGTTGCAATGTGCAAGACAGGCTGCTTGCCGGGCCGCCCTCGGAACATCTGGCCCAGCAGGCCCAGAC
TGTATCCATCCAAGTTCCCGTTGTATCCAGAGTTCTTAGAGCTTGTGTCTAAAGGGTAATTCCCCAACCCTTCCTTATGAGCATTTTTAG
AACATTGGCTAAGACTATTTTCCCCCAGTAGCGCTTTTTTCTGGATTTGCATTCAGGTGTTATTCTTAATGTTTCTGTCAAAGCTTCTTA
AAAATCTTCACTTGGTTTCAGCCATAGTTCACCTTCCCTGTTCCAGGTTTATTTAATTCCAAAGGTGAGAGTTGGAGTGAGATGTCTTCC
ATATCTATACCTTTGTGCACAGTTGAATGGGAACTGTTTGGGTTTAGGGCATCTTAGAGTTGATTGATGGAAAAAGCAGACAGGAACTGG
TGGGAGGTCAAGTGGGGAAGTTGGTGAATGTGGAATAACTTACCTTTGTGCTCCACTTAAACCAGATGTGTTGCAGCTTTCCTGACATGC
AAGGATCTACTTTAATTCCACACTCTCATTAATAAATTGAATAAAAGGGAATGTTTTGGCACCTGATATAATCTGCCAGGCTATGTGACA

>87239_87239_4_STAT3-C1orf43_STAT3_chr17_40497577_ENST00000404395_C1orf43_chr1_154180124_ENST00000350592_length(amino acids)=179AA_BP=114
MTHGTWSSSISSTVTASQWSCGSFWPLGLRVKIGHMRPAKNHMPLWCFIISWERLTSSIAASCKSRMFSISTIYEESSSFFRAGILRSQW

--------------------------------------------------------------
>87239_87239_5_STAT3-C1orf43_STAT3_chr17_40497577_ENST00000404395_C1orf43_chr1_154180124_ENST00000368519_length(transcript)=982nt_BP=509nt
GGATCCTGGACAGGCACCCCGGCTTGGCGCTGTCTCTCCCCCTCGGCTCGGAGAGGCCCTTCGGCCTGAGGGAGCCTCGCCGCCCGTCCC
CGGCACACGCGCAGCCCCGGCCTCTCGGCCTCTGCCGGAGAAACAGGATGGCCCAATGGAATCAGCTACAGCAGCTTGACACACGGTACC
TGGAGCAGCTCCATCAGCTCTACAGTGACAGCTTCCCAATGGAGCTGCGGCAGTTTCTGGCCCCTTGGATTGAGAGTCAAGATTGGGCAT
ATGCGGCCAGCAAAGAATCACATGCCACTTTGGTGTTTCATAATCTCCTGGGAGAGATTGACCAGCAGTATAGCCGCTTCCTGCAAGAGT
CGAATGTTCTCTATCAGCACAATCTACGAAGAATCAAGCAGTTTCTTCAGAGCAGGTATCTTGAGAAGCCAATGGAGATTGCCCGGATTG
TGGCCCGGTGCCTGTGGGAAGAATCACGCCTTCTACAGACTGCAGCCACTGCGGCCCAGGGTTAAAGCACGAATTGGGAGCTCTCAGCGA
CATCACCAGTCAGCAGCCAAAGACCTAACTCAGTCCCCTGAGGTCTCCCCAACAACCATCCAGGTGACATACCTCCCCTCCAGTCAGAAG
AGTAAACGTGCCAAGCACTTCCTTGAATTGAAGAGCTTTAAGGATAACTATAACACATTGGAGAGTACTCTGTGACGGAGCTGAAGGACT
CTTGCCGTAGATTAAGCCAGTCAGTTGCAATGTGCAAGACAGGCTGCTTGCCGGGCCGCCCTCGGAACATCTGGCCCAGCAGGCCCAGAC
TGTATCCATCCAAGTTCCCGTTGTATCCAGAGTTCTTAGAGCTTGTGTCTAAAGGGTAATTCCCCAACCCTTCCTTATGAGCATTTTTAG

>87239_87239_5_STAT3-C1orf43_STAT3_chr17_40497577_ENST00000404395_C1orf43_chr1_154180124_ENST00000368519_length(amino acids)=179AA_BP=114
MTHGTWSSSISSTVTASQWSCGSFWPLGLRVKIGHMRPAKNHMPLWCFIISWERLTSSIAASCKSRMFSISTIYEESSSFFRAGILRSQW

--------------------------------------------------------------
>87239_87239_6_STAT3-C1orf43_STAT3_chr17_40497577_ENST00000404395_C1orf43_chr1_154180124_ENST00000368521_length(transcript)=1452nt_BP=509nt
GGATCCTGGACAGGCACCCCGGCTTGGCGCTGTCTCTCCCCCTCGGCTCGGAGAGGCCCTTCGGCCTGAGGGAGCCTCGCCGCCCGTCCC
CGGCACACGCGCAGCCCCGGCCTCTCGGCCTCTGCCGGAGAAACAGGATGGCCCAATGGAATCAGCTACAGCAGCTTGACACACGGTACC
TGGAGCAGCTCCATCAGCTCTACAGTGACAGCTTCCCAATGGAGCTGCGGCAGTTTCTGGCCCCTTGGATTGAGAGTCAAGATTGGGCAT
ATGCGGCCAGCAAAGAATCACATGCCACTTTGGTGTTTCATAATCTCCTGGGAGAGATTGACCAGCAGTATAGCCGCTTCCTGCAAGAGT
CGAATGTTCTCTATCAGCACAATCTACGAAGAATCAAGCAGTTTCTTCAGAGCAGGTATCTTGAGAAGCCAATGGAGATTGCCCGGATTG
TGGCCCGGTGCCTGTGGGAAGAATCACGCCTTCTACAGACTGCAGCCACTGCGGCCCAGGGTTAAAGCACGAATTGGGAGCTCTCAGCGA
CATCACCAGTCAGCAGCCAAAGACCTAACTCAGTCCCCTGAGGTCTCCCCAACAACCATCCAGGTGACATACCTCCCCTCCAGTCAGAAG
AGTAAACGTGCCAAGCACTTCCTTGAATTGAAGAGCTTTAAGGATAACTATAACACATTGGAGAGTACTCTGTGACGGAGCTGAAGGACT
CTTGCCGTAGATTAAGCCAGTCAGTTGCAATGTGCAAGACAGGCTGCTTGCCGGGCCGCCCTCGGAACATCTGGCCCAGCAGGCCCAGAC
TGTATCCATCCAAGTTCCCGTTGTATCCAGAGTTCTTAGAGCTTGTGTCTAAAGGGTAATTCCCCAACCCTTCCTTATGAGCATTTTTAG
AACATTGGCTAAGACTATTTTCCCCCAGTAGCGCTTTTTTCTGGATTTGCATTCAGGTGTTATTCTTAATGTTTCTGTCAAAGCTTCTTA
AAAATCTTCACTTGGTTTCAGCCATAGTTCACCTTCCCTGTTCCAGGTTTATTTAATTCCAAAGGTGAGAGTTGGAGTGAGATGTCTTCC
ATATCTATACCTTTGTGCACAGTTGAATGGGAACTGTTTGGGTTTAGGGCATCTTAGAGTTGATTGATGGAAAAAGCAGACAGGAACTGG
TGGGAGGTCAAGTGGGGAAGTTGGTGAATGTGGAATAACTTACCTTTGTGCTCCACTTAAACCAGATGTGTTGCAGCTTTCCTGACATGC
AAGGATCTACTTTAATTCCACACTCTCATTAATAAATTGAATAAAAGGGAATGTTTTGGCACCTGATATAATCTGCCAGGCTATGTGACA
GTAGGAAGGAATGGTTTCCCCTAACAAGCCCAATGCACTGGTCTGACTTTATAAATTATTTAATAAAATGAACTATTATCAAATAAAACG

>87239_87239_6_STAT3-C1orf43_STAT3_chr17_40497577_ENST00000404395_C1orf43_chr1_154180124_ENST00000368521_length(amino acids)=179AA_BP=114
MTHGTWSSSISSTVTASQWSCGSFWPLGLRVKIGHMRPAKNHMPLWCFIISWERLTSSIAASCKSRMFSISTIYEESSSFFRAGILRSQW

--------------------------------------------------------------
>87239_87239_7_STAT3-C1orf43_STAT3_chr17_40497577_ENST00000585517_C1orf43_chr1_154180124_ENST00000350592_length(transcript)=1466nt_BP=537nt
GCAGCCGAGGGAACAAGCCCCAACCGGATCCTGGACAGGCACCCCGGCTTGGCGCTGTCTCTCCCCCTCGGCTCGGAGAGGCCCTTCGGC
CTGAGGGAGCCTCGCCGCCCGTCCCCGGCACACGCGCAGCCCCGGCCTCTCGGCCTCTGCCGGAGAAACAGCAGGATGGCCCAATGGAAT
CAGCTACAGCAGCTTGACACACGGTACCTGGAGCAGCTCCATCAGCTCTACAGTGACAGCTTCCCAATGGAGCTGCGGCAGTTTCTGGCC
CCTTGGATTGAGAGTCAAGATTGGGCATATGCGGCCAGCAAAGAATCACATGCCACTTTGGTGTTTCATAATCTCCTGGGAGAGATTGAC
CAGCAGTATAGCCGCTTCCTGCAAGAGTCGAATGTTCTCTATCAGCACAATCTACGAAGAATCAAGCAGTTTCTTCAGAGCAGGTATCTT
GAGAAGCCAATGGAGATTGCCCGGATTGTGGCCCGGTGCCTGTGGGAAGAATCACGCCTTCTACAGACTGCAGCCACTGCGGCCCAGGGT
TAAAGCACGAATTGGGAGCTCTCAGCGACATCACCAGTCAGCAGCCAAAGACCTAACTCAGTCCCCTGAGGTCTCCCCAACAACCATCCA
GGTGACATACCTCCCCTCCAGTCAGAAGAGTAAACGTGCCAAGCACTTCCTTGAATTGAAGAGCTTTAAGGATAACTATAACACATTGGA
GAGTACTCTGTGACGGAGCTGAAGGACTCTTGCCGTAGATTAAGCCAGTCAGTTGCAATGTGCAAGACAGGCTGCTTGCCGGGCCGCCCT
CGGAACATCTGGCCCAGCAGGCCCAGACTGTATCCATCCAAGTTCCCGTTGTATCCAGAGTTCTTAGAGCTTGTGTCTAAAGGGTAATTC
CCCAACCCTTCCTTATGAGCATTTTTAGAACATTGGCTAAGACTATTTTCCCCCAGTAGCGCTTTTTTCTGGATTTGCATTCAGGTGTTA
TTCTTAATGTTTCTGTCAAAGCTTCTTAAAAATCTTCACTTGGTTTCAGCCATAGTTCACCTTCCCTGTTCCAGGTTTATTTAATTCCAA
AGGTGAGAGTTGGAGTGAGATGTCTTCCATATCTATACCTTTGTGCACAGTTGAATGGGAACTGTTTGGGTTTAGGGCATCTTAGAGTTG
ATTGATGGAAAAAGCAGACAGGAACTGGTGGGAGGTCAAGTGGGGAAGTTGGTGAATGTGGAATAACTTACCTTTGTGCTCCACTTAAAC
CAGATGTGTTGCAGCTTTCCTGACATGCAAGGATCTACTTTAATTCCACACTCTCATTAATAAATTGAATAAAAGGGAATGTTTTGGCAC
CTGATATAATCTGCCAGGCTATGTGACAGTAGGAAGGAATGGTTTCCCCTAACAAGCCCAATGCACTGGTCTGACTTTATAAATTATTTA

>87239_87239_7_STAT3-C1orf43_STAT3_chr17_40497577_ENST00000585517_C1orf43_chr1_154180124_ENST00000350592_length(amino acids)=179AA_BP=114
MTHGTWSSSISSTVTASQWSCGSFWPLGLRVKIGHMRPAKNHMPLWCFIISWERLTSSIAASCKSRMFSISTIYEESSSFFRAGILRSQW

--------------------------------------------------------------
>87239_87239_8_STAT3-C1orf43_STAT3_chr17_40497577_ENST00000585517_C1orf43_chr1_154180124_ENST00000368519_length(transcript)=1010nt_BP=537nt
GCAGCCGAGGGAACAAGCCCCAACCGGATCCTGGACAGGCACCCCGGCTTGGCGCTGTCTCTCCCCCTCGGCTCGGAGAGGCCCTTCGGC
CTGAGGGAGCCTCGCCGCCCGTCCCCGGCACACGCGCAGCCCCGGCCTCTCGGCCTCTGCCGGAGAAACAGCAGGATGGCCCAATGGAAT
CAGCTACAGCAGCTTGACACACGGTACCTGGAGCAGCTCCATCAGCTCTACAGTGACAGCTTCCCAATGGAGCTGCGGCAGTTTCTGGCC
CCTTGGATTGAGAGTCAAGATTGGGCATATGCGGCCAGCAAAGAATCACATGCCACTTTGGTGTTTCATAATCTCCTGGGAGAGATTGAC
CAGCAGTATAGCCGCTTCCTGCAAGAGTCGAATGTTCTCTATCAGCACAATCTACGAAGAATCAAGCAGTTTCTTCAGAGCAGGTATCTT
GAGAAGCCAATGGAGATTGCCCGGATTGTGGCCCGGTGCCTGTGGGAAGAATCACGCCTTCTACAGACTGCAGCCACTGCGGCCCAGGGT
TAAAGCACGAATTGGGAGCTCTCAGCGACATCACCAGTCAGCAGCCAAAGACCTAACTCAGTCCCCTGAGGTCTCCCCAACAACCATCCA
GGTGACATACCTCCCCTCCAGTCAGAAGAGTAAACGTGCCAAGCACTTCCTTGAATTGAAGAGCTTTAAGGATAACTATAACACATTGGA
GAGTACTCTGTGACGGAGCTGAAGGACTCTTGCCGTAGATTAAGCCAGTCAGTTGCAATGTGCAAGACAGGCTGCTTGCCGGGCCGCCCT
CGGAACATCTGGCCCAGCAGGCCCAGACTGTATCCATCCAAGTTCCCGTTGTATCCAGAGTTCTTAGAGCTTGTGTCTAAAGGGTAATTC
CCCAACCCTTCCTTATGAGCATTTTTAGAACATTGGCTAAGACTATTTTCCCCCAGTAGCGCTTTTTTCTGGATTTGCATTCAGGTGTTA

>87239_87239_8_STAT3-C1orf43_STAT3_chr17_40497577_ENST00000585517_C1orf43_chr1_154180124_ENST00000368519_length(amino acids)=179AA_BP=114
MTHGTWSSSISSTVTASQWSCGSFWPLGLRVKIGHMRPAKNHMPLWCFIISWERLTSSIAASCKSRMFSISTIYEESSSFFRAGILRSQW

--------------------------------------------------------------
>87239_87239_9_STAT3-C1orf43_STAT3_chr17_40497577_ENST00000585517_C1orf43_chr1_154180124_ENST00000368521_length(transcript)=1480nt_BP=537nt
GCAGCCGAGGGAACAAGCCCCAACCGGATCCTGGACAGGCACCCCGGCTTGGCGCTGTCTCTCCCCCTCGGCTCGGAGAGGCCCTTCGGC
CTGAGGGAGCCTCGCCGCCCGTCCCCGGCACACGCGCAGCCCCGGCCTCTCGGCCTCTGCCGGAGAAACAGCAGGATGGCCCAATGGAAT
CAGCTACAGCAGCTTGACACACGGTACCTGGAGCAGCTCCATCAGCTCTACAGTGACAGCTTCCCAATGGAGCTGCGGCAGTTTCTGGCC
CCTTGGATTGAGAGTCAAGATTGGGCATATGCGGCCAGCAAAGAATCACATGCCACTTTGGTGTTTCATAATCTCCTGGGAGAGATTGAC
CAGCAGTATAGCCGCTTCCTGCAAGAGTCGAATGTTCTCTATCAGCACAATCTACGAAGAATCAAGCAGTTTCTTCAGAGCAGGTATCTT
GAGAAGCCAATGGAGATTGCCCGGATTGTGGCCCGGTGCCTGTGGGAAGAATCACGCCTTCTACAGACTGCAGCCACTGCGGCCCAGGGT
TAAAGCACGAATTGGGAGCTCTCAGCGACATCACCAGTCAGCAGCCAAAGACCTAACTCAGTCCCCTGAGGTCTCCCCAACAACCATCCA
GGTGACATACCTCCCCTCCAGTCAGAAGAGTAAACGTGCCAAGCACTTCCTTGAATTGAAGAGCTTTAAGGATAACTATAACACATTGGA
GAGTACTCTGTGACGGAGCTGAAGGACTCTTGCCGTAGATTAAGCCAGTCAGTTGCAATGTGCAAGACAGGCTGCTTGCCGGGCCGCCCT
CGGAACATCTGGCCCAGCAGGCCCAGACTGTATCCATCCAAGTTCCCGTTGTATCCAGAGTTCTTAGAGCTTGTGTCTAAAGGGTAATTC
CCCAACCCTTCCTTATGAGCATTTTTAGAACATTGGCTAAGACTATTTTCCCCCAGTAGCGCTTTTTTCTGGATTTGCATTCAGGTGTTA
TTCTTAATGTTTCTGTCAAAGCTTCTTAAAAATCTTCACTTGGTTTCAGCCATAGTTCACCTTCCCTGTTCCAGGTTTATTTAATTCCAA
AGGTGAGAGTTGGAGTGAGATGTCTTCCATATCTATACCTTTGTGCACAGTTGAATGGGAACTGTTTGGGTTTAGGGCATCTTAGAGTTG
ATTGATGGAAAAAGCAGACAGGAACTGGTGGGAGGTCAAGTGGGGAAGTTGGTGAATGTGGAATAACTTACCTTTGTGCTCCACTTAAAC
CAGATGTGTTGCAGCTTTCCTGACATGCAAGGATCTACTTTAATTCCACACTCTCATTAATAAATTGAATAAAAGGGAATGTTTTGGCAC
CTGATATAATCTGCCAGGCTATGTGACAGTAGGAAGGAATGGTTTCCCCTAACAAGCCCAATGCACTGGTCTGACTTTATAAATTATTTA

>87239_87239_9_STAT3-C1orf43_STAT3_chr17_40497577_ENST00000585517_C1orf43_chr1_154180124_ENST00000368521_length(amino acids)=179AA_BP=114
MTHGTWSSSISSTVTASQWSCGSFWPLGLRVKIGHMRPAKNHMPLWCFIISWERLTSSIAASCKSRMFSISTIYEESSSFFRAGILRSQW

--------------------------------------------------------------
>87239_87239_10_STAT3-C1orf43_STAT3_chr17_40497577_ENST00000588969_C1orf43_chr1_154180124_ENST00000350592_length(transcript)=1506nt_BP=577nt
GCGGCGGCGCAGACTGGGAGGGGGAGCCGGGGGTTCCGACGTCGCAGCCGAGGGAACAAGCCCCAACCGGATCCTGGACAGGCACCCCGG
CTTGGCGCTGTCTCTCCCCCTCGGCTCGGAGAGGCCCTTCGGCCTGAGGGAGCCTCGCCGCCCGTCCCCGGCACACGCGCAGCCCCGGCC
TCTCGGCCTCTGCCGGAGAAACAGGATGGCCCAATGGAATCAGCTACAGCAGCTTGACACACGGTACCTGGAGCAGCTCCATCAGCTCTA
CAGTGACAGCTTCCCAATGGAGCTGCGGCAGTTTCTGGCCCCTTGGATTGAGAGTCAAGATTGGGCATATGCGGCCAGCAAAGAATCACA
TGCCACTTTGGTGTTTCATAATCTCCTGGGAGAGATTGACCAGCAGTATAGCCGCTTCCTGCAAGAGTCGAATGTTCTCTATCAGCACAA
TCTACGAAGAATCAAGCAGTTTCTTCAGAGCAGGTATCTTGAGAAGCCAATGGAGATTGCCCGGATTGTGGCCCGGTGCCTGTGGGAAGA
ATCACGCCTTCTACAGACTGCAGCCACTGCGGCCCAGGGTTAAAGCACGAATTGGGAGCTCTCAGCGACATCACCAGTCAGCAGCCAAAG
ACCTAACTCAGTCCCCTGAGGTCTCCCCAACAACCATCCAGGTGACATACCTCCCCTCCAGTCAGAAGAGTAAACGTGCCAAGCACTTCC
TTGAATTGAAGAGCTTTAAGGATAACTATAACACATTGGAGAGTACTCTGTGACGGAGCTGAAGGACTCTTGCCGTAGATTAAGCCAGTC
AGTTGCAATGTGCAAGACAGGCTGCTTGCCGGGCCGCCCTCGGAACATCTGGCCCAGCAGGCCCAGACTGTATCCATCCAAGTTCCCGTT
GTATCCAGAGTTCTTAGAGCTTGTGTCTAAAGGGTAATTCCCCAACCCTTCCTTATGAGCATTTTTAGAACATTGGCTAAGACTATTTTC
CCCCAGTAGCGCTTTTTTCTGGATTTGCATTCAGGTGTTATTCTTAATGTTTCTGTCAAAGCTTCTTAAAAATCTTCACTTGGTTTCAGC
CATAGTTCACCTTCCCTGTTCCAGGTTTATTTAATTCCAAAGGTGAGAGTTGGAGTGAGATGTCTTCCATATCTATACCTTTGTGCACAG
TTGAATGGGAACTGTTTGGGTTTAGGGCATCTTAGAGTTGATTGATGGAAAAAGCAGACAGGAACTGGTGGGAGGTCAAGTGGGGAAGTT
GGTGAATGTGGAATAACTTACCTTTGTGCTCCACTTAAACCAGATGTGTTGCAGCTTTCCTGACATGCAAGGATCTACTTTAATTCCACA
CTCTCATTAATAAATTGAATAAAAGGGAATGTTTTGGCACCTGATATAATCTGCCAGGCTATGTGACAGTAGGAAGGAATGGTTTCCCCT

>87239_87239_10_STAT3-C1orf43_STAT3_chr17_40497577_ENST00000588969_C1orf43_chr1_154180124_ENST00000350592_length(amino acids)=189AA_BP=
MGGGAGGSDVAAEGTSPNRILDRHPGLALSLPLGSERPFGLREPRRPSPAHAQPRPLGLCRRNRMAQWNQLQQLDTRYLEQLHQLYSDSF
PMELRQFLAPWIESQDWAYAASKESHATLVFHNLLGEIDQQYSRFLQESNVLYQHNLRRIKQFLQSRYLEKPMEIARIVARCLWEESRLL

--------------------------------------------------------------
>87239_87239_11_STAT3-C1orf43_STAT3_chr17_40497577_ENST00000588969_C1orf43_chr1_154180124_ENST00000368519_length(transcript)=1050nt_BP=577nt
GCGGCGGCGCAGACTGGGAGGGGGAGCCGGGGGTTCCGACGTCGCAGCCGAGGGAACAAGCCCCAACCGGATCCTGGACAGGCACCCCGG
CTTGGCGCTGTCTCTCCCCCTCGGCTCGGAGAGGCCCTTCGGCCTGAGGGAGCCTCGCCGCCCGTCCCCGGCACACGCGCAGCCCCGGCC
TCTCGGCCTCTGCCGGAGAAACAGGATGGCCCAATGGAATCAGCTACAGCAGCTTGACACACGGTACCTGGAGCAGCTCCATCAGCTCTA
CAGTGACAGCTTCCCAATGGAGCTGCGGCAGTTTCTGGCCCCTTGGATTGAGAGTCAAGATTGGGCATATGCGGCCAGCAAAGAATCACA
TGCCACTTTGGTGTTTCATAATCTCCTGGGAGAGATTGACCAGCAGTATAGCCGCTTCCTGCAAGAGTCGAATGTTCTCTATCAGCACAA
TCTACGAAGAATCAAGCAGTTTCTTCAGAGCAGGTATCTTGAGAAGCCAATGGAGATTGCCCGGATTGTGGCCCGGTGCCTGTGGGAAGA
ATCACGCCTTCTACAGACTGCAGCCACTGCGGCCCAGGGTTAAAGCACGAATTGGGAGCTCTCAGCGACATCACCAGTCAGCAGCCAAAG
ACCTAACTCAGTCCCCTGAGGTCTCCCCAACAACCATCCAGGTGACATACCTCCCCTCCAGTCAGAAGAGTAAACGTGCCAAGCACTTCC
TTGAATTGAAGAGCTTTAAGGATAACTATAACACATTGGAGAGTACTCTGTGACGGAGCTGAAGGACTCTTGCCGTAGATTAAGCCAGTC
AGTTGCAATGTGCAAGACAGGCTGCTTGCCGGGCCGCCCTCGGAACATCTGGCCCAGCAGGCCCAGACTGTATCCATCCAAGTTCCCGTT
GTATCCAGAGTTCTTAGAGCTTGTGTCTAAAGGGTAATTCCCCAACCCTTCCTTATGAGCATTTTTAGAACATTGGCTAAGACTATTTTC

>87239_87239_11_STAT3-C1orf43_STAT3_chr17_40497577_ENST00000588969_C1orf43_chr1_154180124_ENST00000368519_length(amino acids)=189AA_BP=
MGGGAGGSDVAAEGTSPNRILDRHPGLALSLPLGSERPFGLREPRRPSPAHAQPRPLGLCRRNRMAQWNQLQQLDTRYLEQLHQLYSDSF
PMELRQFLAPWIESQDWAYAASKESHATLVFHNLLGEIDQQYSRFLQESNVLYQHNLRRIKQFLQSRYLEKPMEIARIVARCLWEESRLL

--------------------------------------------------------------
>87239_87239_12_STAT3-C1orf43_STAT3_chr17_40497577_ENST00000588969_C1orf43_chr1_154180124_ENST00000368521_length(transcript)=1520nt_BP=577nt
GCGGCGGCGCAGACTGGGAGGGGGAGCCGGGGGTTCCGACGTCGCAGCCGAGGGAACAAGCCCCAACCGGATCCTGGACAGGCACCCCGG
CTTGGCGCTGTCTCTCCCCCTCGGCTCGGAGAGGCCCTTCGGCCTGAGGGAGCCTCGCCGCCCGTCCCCGGCACACGCGCAGCCCCGGCC
TCTCGGCCTCTGCCGGAGAAACAGGATGGCCCAATGGAATCAGCTACAGCAGCTTGACACACGGTACCTGGAGCAGCTCCATCAGCTCTA
CAGTGACAGCTTCCCAATGGAGCTGCGGCAGTTTCTGGCCCCTTGGATTGAGAGTCAAGATTGGGCATATGCGGCCAGCAAAGAATCACA
TGCCACTTTGGTGTTTCATAATCTCCTGGGAGAGATTGACCAGCAGTATAGCCGCTTCCTGCAAGAGTCGAATGTTCTCTATCAGCACAA
TCTACGAAGAATCAAGCAGTTTCTTCAGAGCAGGTATCTTGAGAAGCCAATGGAGATTGCCCGGATTGTGGCCCGGTGCCTGTGGGAAGA
ATCACGCCTTCTACAGACTGCAGCCACTGCGGCCCAGGGTTAAAGCACGAATTGGGAGCTCTCAGCGACATCACCAGTCAGCAGCCAAAG
ACCTAACTCAGTCCCCTGAGGTCTCCCCAACAACCATCCAGGTGACATACCTCCCCTCCAGTCAGAAGAGTAAACGTGCCAAGCACTTCC
TTGAATTGAAGAGCTTTAAGGATAACTATAACACATTGGAGAGTACTCTGTGACGGAGCTGAAGGACTCTTGCCGTAGATTAAGCCAGTC
AGTTGCAATGTGCAAGACAGGCTGCTTGCCGGGCCGCCCTCGGAACATCTGGCCCAGCAGGCCCAGACTGTATCCATCCAAGTTCCCGTT
GTATCCAGAGTTCTTAGAGCTTGTGTCTAAAGGGTAATTCCCCAACCCTTCCTTATGAGCATTTTTAGAACATTGGCTAAGACTATTTTC
CCCCAGTAGCGCTTTTTTCTGGATTTGCATTCAGGTGTTATTCTTAATGTTTCTGTCAAAGCTTCTTAAAAATCTTCACTTGGTTTCAGC
CATAGTTCACCTTCCCTGTTCCAGGTTTATTTAATTCCAAAGGTGAGAGTTGGAGTGAGATGTCTTCCATATCTATACCTTTGTGCACAG
TTGAATGGGAACTGTTTGGGTTTAGGGCATCTTAGAGTTGATTGATGGAAAAAGCAGACAGGAACTGGTGGGAGGTCAAGTGGGGAAGTT
GGTGAATGTGGAATAACTTACCTTTGTGCTCCACTTAAACCAGATGTGTTGCAGCTTTCCTGACATGCAAGGATCTACTTTAATTCCACA
CTCTCATTAATAAATTGAATAAAAGGGAATGTTTTGGCACCTGATATAATCTGCCAGGCTATGTGACAGTAGGAAGGAATGGTTTCCCCT

>87239_87239_12_STAT3-C1orf43_STAT3_chr17_40497577_ENST00000588969_C1orf43_chr1_154180124_ENST00000368521_length(amino acids)=189AA_BP=
MGGGAGGSDVAAEGTSPNRILDRHPGLALSLPLGSERPFGLREPRRPSPAHAQPRPLGLCRRNRMAQWNQLQQLDTRYLEQLHQLYSDSF
PMELRQFLAPWIESQDWAYAASKESHATLVFHNLLGEIDQQYSRFLQESNVLYQHNLRRIKQFLQSRYLEKPMEIARIVARCLWEESRLL

--------------------------------------------------------------

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Fusion Gene PPI Analysis for STAT3-C1orf43


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for STAT3-C1orf43


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for STAT3-C1orf43


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource