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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:STIP1-PAK1 (FusionGDB2 ID:87428)

Fusion Gene Summary for STIP1-PAK1

check button Fusion gene summary
Fusion gene informationFusion gene name: STIP1-PAK1
Fusion gene ID: 87428
HgeneTgene
Gene symbol

STIP1

PAK1

Gene ID

10963

5585

Gene namestress induced phosphoprotein 1protein kinase N1
SynonymsHEL-S-94n|HOP|IEF-SSP-3521|P60|STI1|STI1LDBK|PAK-1|PAK1|PKN|PKN-ALPHA|PRK1|PRKCL1
Cytomap

11q13.1

19p13.12

Type of geneprotein-codingprotein-coding
Descriptionstress-induced-phosphoprotein 1Hsp70/Hsp90-organizing proteinNY-REN-11 antigenepididymis secretory sperm binding protein Li 94nhsc70/Hsp90-organizing proteinrenal carcinoma antigen NY-REN-11transformation-sensitive protein IEF SSP 3521serine/threonine-protein kinase N1protease-activated kinase 1protein kinase C-like 1protein kinase C-like PKNprotein kinase C-related kinase 1protein kinase PKN-alphaserine-threonine kinase Nserine/threonine protein kinase N
Modification date2020032920200329
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000305218, ENST00000538945, 
ENST00000543847, ENST00000358794, 
ENST00000540501, 		ENST00000525542, 
ENST00000278568, ENST00000356341, 
ENST00000528203, ENST00000530617, 
Fusion gene scores* DoF score14 X 8 X 10=112022 X 17 X 10=3740
# samples 1526
** MAII scorelog2(15/1120*10)=-2.90046432644909
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(26/3740*10)=-3.84645474174655
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: STIP1 [Title/Abstract] AND PAK1 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointSTIP1(63953742)-PAK1(77043912), # samples:3
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
TgenePAK1

GO:0006357

regulation of transcription by RNA polymerase II

12514133

TgenePAK1

GO:0006468

protein phosphorylation

17332740

TgenePAK1

GO:0035407

histone H3-T11 phosphorylation

18066052


check buttonFusion gene breakpoints across STIP1 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across PAK1 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4LUSCTCGA-94-7557-01ASTIP1chr11

63953742

+PAK1chr11

77043912

-
ChimerDB4LUSCTCGA-94-7557STIP1chr11

63953742

+PAK1chr11

77043912

-


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Fusion Gene ORF analysis for STIP1-PAK1

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-5UTRENST00000305218ENST00000525542STIP1chr11

63953742

+PAK1chr11

77043912

-
5CDS-5UTRENST00000538945ENST00000525542STIP1chr11

63953742

+PAK1chr11

77043912

-
5CDS-5UTRENST00000543847ENST00000525542STIP1chr11

63953742

+PAK1chr11

77043912

-
In-frameENST00000305218ENST00000278568STIP1chr11

63953742

+PAK1chr11

77043912

-
In-frameENST00000305218ENST00000356341STIP1chr11

63953742

+PAK1chr11

77043912

-
In-frameENST00000305218ENST00000528203STIP1chr11

63953742

+PAK1chr11

77043912

-
In-frameENST00000305218ENST00000530617STIP1chr11

63953742

+PAK1chr11

77043912

-
In-frameENST00000538945ENST00000278568STIP1chr11

63953742

+PAK1chr11

77043912

-
In-frameENST00000538945ENST00000356341STIP1chr11

63953742

+PAK1chr11

77043912

-
In-frameENST00000538945ENST00000528203STIP1chr11

63953742

+PAK1chr11

77043912

-
In-frameENST00000538945ENST00000530617STIP1chr11

63953742

+PAK1chr11

77043912

-
In-frameENST00000543847ENST00000278568STIP1chr11

63953742

+PAK1chr11

77043912

-
In-frameENST00000543847ENST00000356341STIP1chr11

63953742

+PAK1chr11

77043912

-
In-frameENST00000543847ENST00000528203STIP1chr11

63953742

+PAK1chr11

77043912

-
In-frameENST00000543847ENST00000530617STIP1chr11

63953742

+PAK1chr11

77043912

-
intron-3CDSENST00000358794ENST00000278568STIP1chr11

63953742

+PAK1chr11

77043912

-
intron-3CDSENST00000358794ENST00000356341STIP1chr11

63953742

+PAK1chr11

77043912

-
intron-3CDSENST00000358794ENST00000528203STIP1chr11

63953742

+PAK1chr11

77043912

-
intron-3CDSENST00000358794ENST00000530617STIP1chr11

63953742

+PAK1chr11

77043912

-
intron-3CDSENST00000540501ENST00000278568STIP1chr11

63953742

+PAK1chr11

77043912

-
intron-3CDSENST00000540501ENST00000356341STIP1chr11

63953742

+PAK1chr11

77043912

-
intron-3CDSENST00000540501ENST00000528203STIP1chr11

63953742

+PAK1chr11

77043912

-
intron-3CDSENST00000540501ENST00000530617STIP1chr11

63953742

+PAK1chr11

77043912

-
intron-5UTRENST00000358794ENST00000525542STIP1chr11

63953742

+PAK1chr11

77043912

-
intron-5UTRENST00000540501ENST00000525542STIP1chr11

63953742

+PAK1chr11

77043912

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000305218STIP1chr1163953742+ENST00000356341PAK1chr1177043912-19481561230892112
ENST00000305218STIP1chr1163953742+ENST00000530617PAK1chr1177043912-14321561024686112
ENST00000305218STIP1chr1163953742+ENST00000278568PAK1chr1177043912-75615614740485
ENST00000305218STIP1chr1163953742+ENST00000528203PAK1chr1177043912-68015660631995
ENST00000538945STIP1chr1163953742+ENST00000356341PAK1chr1177043912-1859671141803112
ENST00000538945STIP1chr1163953742+ENST00000530617PAK1chr1177043912-134367935597112
ENST00000538945STIP1chr1163953742+ENST00000278568PAK1chr1177043912-667675831585
ENST00000538945STIP1chr1163953742+ENST00000528203PAK1chr1177043912-5916751723095
ENST00000543847STIP1chr1163953742+ENST00000356341PAK1chr1177043912-1838461120782112
ENST00000543847STIP1chr1163953742+ENST00000530617PAK1chr1177043912-132246914576112
ENST00000543847STIP1chr1163953742+ENST00000278568PAK1chr1177043912-646463729485
ENST00000543847STIP1chr1163953742+ENST00000528203PAK1chr1177043912-5704649620995

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000305218ENST00000356341STIP1chr1163953742+PAK1chr1177043912-0.101660630.8983394
ENST00000305218ENST00000530617STIP1chr1163953742+PAK1chr1177043912-0.305151520.6948485
ENST00000305218ENST00000278568STIP1chr1163953742+PAK1chr1177043912-0.0396008570.9603991
ENST00000305218ENST00000528203STIP1chr1163953742+PAK1chr1177043912-0.0291920680.97080797
ENST00000538945ENST00000356341STIP1chr1163953742+PAK1chr1177043912-0.164540340.83545965
ENST00000538945ENST00000530617STIP1chr1163953742+PAK1chr1177043912-0.59294210.40705788
ENST00000538945ENST00000278568STIP1chr1163953742+PAK1chr1177043912-0.0527145940.94728535
ENST00000538945ENST00000528203STIP1chr1163953742+PAK1chr1177043912-0.0242582950.97574174
ENST00000543847ENST00000356341STIP1chr1163953742+PAK1chr1177043912-0.365447130.63455284
ENST00000543847ENST00000530617STIP1chr1163953742+PAK1chr1177043912-0.65959560.34040433
ENST00000543847ENST00000278568STIP1chr1163953742+PAK1chr1177043912-0.0501453280.9498546
ENST00000543847ENST00000528203STIP1chr1163953742+PAK1chr1177043912-0.0260468550.9739532

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Fusion Genomic Features for STIP1-PAK1


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for STIP1-PAK1


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr11:63953742/chr11:77043912)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneSTIP1chr11:63953742chr11:77043912ENST00000305218+114130_1693544.0DomainNote=STI1 1
HgeneSTIP1chr11:63953742chr11:77043912ENST00000305218+114492_5313544.0DomainNote=STI1 2
HgeneSTIP1chr11:63953742chr11:77043912ENST00000305218+114222_2393544.0MotifBipartite nuclear localization signal
HgeneSTIP1chr11:63953742chr11:77043912ENST00000305218+114225_2583544.0RepeatNote=TPR 4
HgeneSTIP1chr11:63953742chr11:77043912ENST00000305218+114259_2923544.0RepeatNote=TPR 5
HgeneSTIP1chr11:63953742chr11:77043912ENST00000305218+114300_3333544.0RepeatNote=TPR 6
HgeneSTIP1chr11:63953742chr11:77043912ENST00000305218+114360_3933544.0RepeatNote=TPR 7
HgeneSTIP1chr11:63953742chr11:77043912ENST00000305218+11438_713544.0RepeatNote=TPR 2
HgeneSTIP1chr11:63953742chr11:77043912ENST00000305218+114394_4273544.0RepeatNote=TPR 8
HgeneSTIP1chr11:63953742chr11:77043912ENST00000305218+114428_4613544.0RepeatNote=TPR 9
HgeneSTIP1chr11:63953742chr11:77043912ENST00000305218+1144_373544.0RepeatNote=TPR 1
HgeneSTIP1chr11:63953742chr11:77043912ENST00000305218+11472_1053544.0RepeatNote=TPR 3
TgenePAK1chr11:63953742chr11:77043912ENST000002785681216270_521471554.0DomainProtein kinase
TgenePAK1chr11:63953742chr11:77043912ENST00000278568121675_88471554.0DomainCRIB
TgenePAK1chr11:63953742chr11:77043912ENST000003563411215270_521471546.0DomainProtein kinase
TgenePAK1chr11:63953742chr11:77043912ENST00000356341121575_88471546.0DomainCRIB
TgenePAK1chr11:63953742chr11:77043912ENST000002785681216276_284471554.0Nucleotide bindingNote=ATP
TgenePAK1chr11:63953742chr11:77043912ENST000002785681216345_347471554.0Nucleotide bindingNote=ATP
TgenePAK1chr11:63953742chr11:77043912ENST000003563411215276_284471546.0Nucleotide bindingNote=ATP
TgenePAK1chr11:63953742chr11:77043912ENST000003563411215345_347471546.0Nucleotide bindingNote=ATP
TgenePAK1chr11:63953742chr11:77043912ENST00000278568121670_140471554.0RegionNote=Autoregulatory region
TgenePAK1chr11:63953742chr11:77043912ENST00000278568121675_105471554.0RegionNote=GTPase-binding
TgenePAK1chr11:63953742chr11:77043912ENST00000356341121570_140471546.0RegionNote=Autoregulatory region
TgenePAK1chr11:63953742chr11:77043912ENST00000356341121575_105471546.0RegionNote=GTPase-binding


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Fusion Gene Sequence for STIP1-PAK1


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>87428_87428_1_STIP1-PAK1_STIP1_chr11_63953742_ENST00000305218_PAK1_chr11_77043912_ENST00000278568_length(transcript)=756nt_BP=156nt
CTAGAAGAACTCGACCAGTGAGCAGGCGAGGAAGGGGCGGGAGCCGGGGTCCCGGTAGCTTCTAGTAGGTTCCAGAAGGCGGCGCGTGCG
GTTGGGAACGCGGAGCGGACGGATTCGATTCAACGGGGTTCCGGACCGCGCTGCGCTATGGAGCAGGCCTTGTACCTCATTGCCACCAAT
GGGACCCCAGAACTTCAGAACCCAGAGAAGCTGTCAGCTATCTTCCGGGACTTTCTGAACCGCTGTCTCGAGATGGATGTGGAGAAGAGA
GGTTCAGCTAAAGAGCTGCTACAGGTGAGAAAACTGAGGTTTCAAGTGTTTAGTAACTTTTCCATGATAGCTGCATCAATTCCTGAAGAT
TGCCAAGCCCCTCTCCAGCCTCACTCCACTGATTGCTGCAGCTAAGGAGGCAACAAAGAACAATCACTAAAACCACACTCACCCCAGCCT
CATTGTGCCAAGCCTTCTGTGAGATAAATGCACATTTCAGAAATTCCAACTCCTGATGCCCTCTTCTCCTTGCCTTGCTTCTCCCATTTC
CTGATCTAGCACTCCTCAAGACTTTGATCCTTGGAAACCGTGTGTCCAGCATTGAAGAGAACTGCAACTGAATGACTAATCAGATGATGG
CCATTTCTAAATAAGGAATTTCCTCCCAATTCATGGATATGAGGGTGGTTTATGATTAAGGGTTTATATAAATAAATGTTTCTAGTCTTC

>87428_87428_1_STIP1-PAK1_STIP1_chr11_63953742_ENST00000305218_PAK1_chr11_77043912_ENST00000278568_length(amino acids)=85AA_BP=2

--------------------------------------------------------------
>87428_87428_2_STIP1-PAK1_STIP1_chr11_63953742_ENST00000305218_PAK1_chr11_77043912_ENST00000356341_length(transcript)=1948nt_BP=156nt
CTAGAAGAACTCGACCAGTGAGCAGGCGAGGAAGGGGCGGGAGCCGGGGTCCCGGTAGCTTCTAGTAGGTTCCAGAAGGCGGCGCGTGCG
GTTGGGAACGCGGAGCGGACGGATTCGATTCAACGGGGTTCCGGACCGCGCTGCGCTATGGAGCAGGCCTTGTACCTCATTGCCACCAAT
GGGACCCCAGAACTTCAGAACCCAGAGAAGCTGTCAGCTATCTTCCGGGACTTTCTGAACCGCTGTCTCGAGATGGATGTGGAGAAGAGA
GGTTCAGCTAAAGAGCTGCTACAGCATCAATTCCTGAAGATTGCCAAGCCCCTCTCCAGCCTCACTCCACTGATTGCTGCAGCTAAGGAG
GCAACAAAGAACAATCACTAAAACCACACTCACCCCAGCCTCATTGTGCCAAGCCTTCTGTGAGATAAATGCACATTTCAGAAATTCCAA
CTCCTGATGCCCTCTTCTCCTTGCCTTGCTTCTCCCATTTCCTGATCTAGCACTCCTCAAGACTTTGATCCTTGGAAACCGTGTGTCCAG
CATTGAAGAGAACTGCAACTGAATGACTAATCAGATGATGGCCATTTCTAAATAAGGAATTTCCTCCCAATTCATGGATATGAGGGTGGT
TTATGATTAAGGGTTTATATAAATAAATGTTTCTAGTCTTCCGTGTGTCAAAATCCTCACCTCCTTCATAACCATCTCCCACAATTAATT
CTTGACTATATAAATTTATGGTTTGATAATATTATCAATTTGTAATCAATTGAGATTTCTTTAGTGCTTGCTTTTCTGTGACTCAACTGC
CCAGACACCTCATTGTACTTGAAAACTGGAACAGCTTGGGAATGCCATGGGGTTTGATAATCTGCCAGGGACATGAAGAGGCTCAGCTTC
CTGGACCATGACTTTGGCTCAGCTGATCCTGACATGGGAGAACAACCACATTTTTCTTTGTGTGTGCTTCTAGCAGCTGTTCGGGAGGAC
CTTGACCCAATAGTGTTCCCATGCTGTTTCTTGTGAAATGCTCTCGGCTATGTAGCAGCTTTTGATTCCCTGCATACCCTAGGCTGCTGC
CCCTATCCTGTCCCTTGTTTATAACATTGAGAGGTTTTCTAGGGCACATACTGAGTGAGAGCAGTGTTGAGAAGTCGGGGAAAATGGTGA
CTACTTTTAGAGCAAGGCTGGGCATCAGCACCTGTCCAGCTCTACTTGTGTGATGTTTCAGGAACTCAGCCCCTTTTTCTGCCTAGGATA
AGGAGCTGAAAGATTAACTTGGATCTTCTAATGGTCCAAATCTTTTGGTCACAATAAAGAGTCTCCAAATTAGAGACTGCATGTTAGTTC
TGGATGGATTTGGTGGCCTGACATGATACCCTGCCAGCTGTGAGGGGACCCCGTTTTTAAGATGCATGGCCAAGCTCTCTGCAAATGGAA
ATGCTTACACTGGGTGTTGGGGATGTTTGCTACCTCCTGCTATTTTTGTGGTTTTGGTTCTCCCACTATGGTAGGACCCCTGGCCAGCAT
TGTGGCTTGTCATGTCAGCCCCATTGACTACCTTCTCATGCTCTGAGGTACTACTGCCTCTGCAGCACAAATTTCTATTTCTGTCAATAA
AAGGAGATGAAAATATTCTATTGGAGTATGCCTTTCTTTTTTCTCTTCGTTTTTTCTTTCCTTTTCTAATTTTTTATATGAAATAATGAG
TAGTTTCTTCCTGAACCATTTGAGAGTGGTAAGTTGCAGATAGAATGCCCCTTTACCACTATATACCTGAATGTGTATTCTTTCTTTTTA
ACACTTTTATTTTAAATATAAATTAAGAGAAATGGGCCAAAACCATTTGTATTGTTTAAAGAATAATTATAAACACACTTGTATCCACCA

>87428_87428_2_STIP1-PAK1_STIP1_chr11_63953742_ENST00000305218_PAK1_chr11_77043912_ENST00000356341_length(amino acids)=112AA_BP=
MKHHTSRAGQVLMPSLALKVVTIFPDFSTLLSLSMCPRKPLNVINKGQDRGSSLGYAGNQKLLHSREHFTRNSMGTLLGQGPPEQLLEAH

--------------------------------------------------------------
>87428_87428_3_STIP1-PAK1_STIP1_chr11_63953742_ENST00000305218_PAK1_chr11_77043912_ENST00000528203_length(transcript)=680nt_BP=156nt
CTAGAAGAACTCGACCAGTGAGCAGGCGAGGAAGGGGCGGGAGCCGGGGTCCCGGTAGCTTCTAGTAGGTTCCAGAAGGCGGCGCGTGCG
GTTGGGAACGCGGAGCGGACGGATTCGATTCAACGGGGTTCCGGACCGCGCTGCGCTATGGAGCAGGCCTTGTACCTCATTGCCACCAAT
GGGACCCCAGAACTTCAGAACCCAGAGAAGCTGTCAGCTATCTTCCGGGACTTTCTGAACCGCTGTCTCGAGATGGATGTGGAGAAGAGA
GGTTCAGCTAAAGAGCTGCTACAGGTGAGAAAACTGAGGTTTCAAGTGTTTAGTAACTTTTCCATGATAGCTGCATCAATTCCTGAAGAT
TGCCAAGCCCCTCTCCAGCCTCACTCCACTGATTGCTGCAGCTAAGGAGGCAACAAAGAACAATCACTAAAACCACACTCACCCCAGCCT
CATTGTGCCAAGCCTTCTGTGAGATAAATGCACATTTCAGAAATTCCAACTCCTGATGCCCTCTTCTCCTTGCCTTGCTTCTCCCATTTC
CTGATCTAGCACTCCTCAAGACTTTGATCCTTGGAAACCGTGTGTCCAGCATTGAAGAGAACTGCAACTGAATGACTAATCAGATGATGG

>87428_87428_3_STIP1-PAK1_STIP1_chr11_63953742_ENST00000305218_PAK1_chr11_77043912_ENST00000528203_length(amino acids)=95AA_BP=
MQFSSMLDTRFPRIKVLRSARSGNGRSKARRRGHQELEFLKCAFISQKAWHNEAGVSVVLVIVLCCLLSCSNQWSEAGEGLGNLQELMQL

--------------------------------------------------------------
>87428_87428_4_STIP1-PAK1_STIP1_chr11_63953742_ENST00000305218_PAK1_chr11_77043912_ENST00000530617_length(transcript)=1432nt_BP=156nt
CTAGAAGAACTCGACCAGTGAGCAGGCGAGGAAGGGGCGGGAGCCGGGGTCCCGGTAGCTTCTAGTAGGTTCCAGAAGGCGGCGCGTGCG
GTTGGGAACGCGGAGCGGACGGATTCGATTCAACGGGGTTCCGGACCGCGCTGCGCTATGGAGCAGGCCTTGTACCTCATTGCCACCAAT
GGGACCCCAGAACTTCAGAACCCAGAGAAGCTGTCAGCTATCTTCCGGGACTTTCTGAACCGCTGTCTCGAGATGGATGTGGAGAAGAGA
GGTTCAGCTAAAGAGCTGCTACAGCACTCCTCAAGACTTTGATCCTTGGAAACCGTGTGTCCAGCATTGAAGAGAACTGCAACTGAATGA
CTAATCAGATGATGGCCATTTCTAAATAAGGAATTTCCTCCCAATTCATGGATATGAGGGTGGTTTATGATTAAGGGTTTATATAAATAA
ATGTTTCTAGTCTTCCGTGTGTCAAAATCCTCACCTCCTTCATAACCATCTCCCACAATTAATTCTTGACTATATAAATTTATGGTTTGA
TAATATTATCAATTTGTAATCAATTGAGATTTCTTTAGTGCTTGCTTTTCTGTGACTCAACTGCCCAGACACCTCATTGTACTTGAAAAC
TGGAACAGCTTGGGAATGCCATGGGGTTTGATAATCTGCCAGGGACATGAAGAGGCTCAGCTTCCTGGACCATGACTTTGGCTCAGCTGA
TCCTGACATGGGAGAACAACCACATTTTTCTTTGTGTGTGCTTCTAGCAGCTGTTCGGGAGGACCTTGACCCAATAGTGTTCCCATGCTG
TTTCTTGTGAAATGCTCTCGGCTATGTAGCAGCTTTTGATTCCCTGCATACCCTAGGCTGCTGCCCCTATCCTGTCCCTTGTTTATAACA
TTGAGAGGTTTTCTAGGGCACATACTGAGTGAGAGCAGTGTTGAGAAGTCGGGGAAAATGGTGACTACTTTTAGAGCAAGGCTGGGCATC
AGCACCTGTCCAGCTCTACTTGTGTGATGTTTCAGGAACTCAGCCCCTTTTTCTGCCTAGGATAAGGAGCTGAAAGATTAACTTGGATCT
TCTAATGGTCCAAATCTTTTGGTCACAATAAAGAGTCTCCAAATTAGAGACTGCATGTTAGTTCTGGATGGATTTGGTGGCCTGACATGA
TACCCTGCCAGCTGTGAGGGGACCCCGTTTTTAAGATGCATGGCCAAGCTCTCTGCAAATGGAAATGCTTACACTGGGTGTTGGGGATGT
TTGCTACCTCCTGCTATTTTTGTGGTTTTGGTTCTCCCACTATGGTAGGACCCCTGGCCAGCATTGTGGCTTGTCATGTCAGCCCCATTG

>87428_87428_4_STIP1-PAK1_STIP1_chr11_63953742_ENST00000305218_PAK1_chr11_77043912_ENST00000530617_length(amino acids)=112AA_BP=
MKHHTSRAGQVLMPSLALKVVTIFPDFSTLLSLSMCPRKPLNVINKGQDRGSSLGYAGNQKLLHSREHFTRNSMGTLLGQGPPEQLLEAH

--------------------------------------------------------------
>87428_87428_5_STIP1-PAK1_STIP1_chr11_63953742_ENST00000538945_PAK1_chr11_77043912_ENST00000278568_length(transcript)=667nt_BP=67nt
GGTTGGGAACGCGGAGCGGACGGATTCGATTCAACGGGGTTCCGGACCGCGCTGCGCTATGGAGCAGGCCTTGTACCTCATTGCCACCAA
TGGGACCCCAGAACTTCAGAACCCAGAGAAGCTGTCAGCTATCTTCCGGGACTTTCTGAACCGCTGTCTCGAGATGGATGTGGAGAAGAG
AGGTTCAGCTAAAGAGCTGCTACAGGTGAGAAAACTGAGGTTTCAAGTGTTTAGTAACTTTTCCATGATAGCTGCATCAATTCCTGAAGA
TTGCCAAGCCCCTCTCCAGCCTCACTCCACTGATTGCTGCAGCTAAGGAGGCAACAAAGAACAATCACTAAAACCACACTCACCCCAGCC
TCATTGTGCCAAGCCTTCTGTGAGATAAATGCACATTTCAGAAATTCCAACTCCTGATGCCCTCTTCTCCTTGCCTTGCTTCTCCCATTT
CCTGATCTAGCACTCCTCAAGACTTTGATCCTTGGAAACCGTGTGTCCAGCATTGAAGAGAACTGCAACTGAATGACTAATCAGATGATG
GCCATTTCTAAATAAGGAATTTCCTCCCAATTCATGGATATGAGGGTGGTTTATGATTAAGGGTTTATATAAATAAATGTTTCTAGTCTT

>87428_87428_5_STIP1-PAK1_STIP1_chr11_63953742_ENST00000538945_PAK1_chr11_77043912_ENST00000278568_length(amino acids)=85AA_BP=2

--------------------------------------------------------------
>87428_87428_6_STIP1-PAK1_STIP1_chr11_63953742_ENST00000538945_PAK1_chr11_77043912_ENST00000356341_length(transcript)=1859nt_BP=67nt
GGTTGGGAACGCGGAGCGGACGGATTCGATTCAACGGGGTTCCGGACCGCGCTGCGCTATGGAGCAGGCCTTGTACCTCATTGCCACCAA
TGGGACCCCAGAACTTCAGAACCCAGAGAAGCTGTCAGCTATCTTCCGGGACTTTCTGAACCGCTGTCTCGAGATGGATGTGGAGAAGAG
AGGTTCAGCTAAAGAGCTGCTACAGCATCAATTCCTGAAGATTGCCAAGCCCCTCTCCAGCCTCACTCCACTGATTGCTGCAGCTAAGGA
GGCAACAAAGAACAATCACTAAAACCACACTCACCCCAGCCTCATTGTGCCAAGCCTTCTGTGAGATAAATGCACATTTCAGAAATTCCA
ACTCCTGATGCCCTCTTCTCCTTGCCTTGCTTCTCCCATTTCCTGATCTAGCACTCCTCAAGACTTTGATCCTTGGAAACCGTGTGTCCA
GCATTGAAGAGAACTGCAACTGAATGACTAATCAGATGATGGCCATTTCTAAATAAGGAATTTCCTCCCAATTCATGGATATGAGGGTGG
TTTATGATTAAGGGTTTATATAAATAAATGTTTCTAGTCTTCCGTGTGTCAAAATCCTCACCTCCTTCATAACCATCTCCCACAATTAAT
TCTTGACTATATAAATTTATGGTTTGATAATATTATCAATTTGTAATCAATTGAGATTTCTTTAGTGCTTGCTTTTCTGTGACTCAACTG
CCCAGACACCTCATTGTACTTGAAAACTGGAACAGCTTGGGAATGCCATGGGGTTTGATAATCTGCCAGGGACATGAAGAGGCTCAGCTT
CCTGGACCATGACTTTGGCTCAGCTGATCCTGACATGGGAGAACAACCACATTTTTCTTTGTGTGTGCTTCTAGCAGCTGTTCGGGAGGA
CCTTGACCCAATAGTGTTCCCATGCTGTTTCTTGTGAAATGCTCTCGGCTATGTAGCAGCTTTTGATTCCCTGCATACCCTAGGCTGCTG
CCCCTATCCTGTCCCTTGTTTATAACATTGAGAGGTTTTCTAGGGCACATACTGAGTGAGAGCAGTGTTGAGAAGTCGGGGAAAATGGTG
ACTACTTTTAGAGCAAGGCTGGGCATCAGCACCTGTCCAGCTCTACTTGTGTGATGTTTCAGGAACTCAGCCCCTTTTTCTGCCTAGGAT
AAGGAGCTGAAAGATTAACTTGGATCTTCTAATGGTCCAAATCTTTTGGTCACAATAAAGAGTCTCCAAATTAGAGACTGCATGTTAGTT
CTGGATGGATTTGGTGGCCTGACATGATACCCTGCCAGCTGTGAGGGGACCCCGTTTTTAAGATGCATGGCCAAGCTCTCTGCAAATGGA
AATGCTTACACTGGGTGTTGGGGATGTTTGCTACCTCCTGCTATTTTTGTGGTTTTGGTTCTCCCACTATGGTAGGACCCCTGGCCAGCA
TTGTGGCTTGTCATGTCAGCCCCATTGACTACCTTCTCATGCTCTGAGGTACTACTGCCTCTGCAGCACAAATTTCTATTTCTGTCAATA
AAAGGAGATGAAAATATTCTATTGGAGTATGCCTTTCTTTTTTCTCTTCGTTTTTTCTTTCCTTTTCTAATTTTTTATATGAAATAATGA
GTAGTTTCTTCCTGAACCATTTGAGAGTGGTAAGTTGCAGATAGAATGCCCCTTTACCACTATATACCTGAATGTGTATTCTTTCTTTTT
AACACTTTTATTTTAAATATAAATTAAGAGAAATGGGCCAAAACCATTTGTATTGTTTAAAGAATAATTATAAACACACTTGTATCCACC

>87428_87428_6_STIP1-PAK1_STIP1_chr11_63953742_ENST00000538945_PAK1_chr11_77043912_ENST00000356341_length(amino acids)=112AA_BP=
MKHHTSRAGQVLMPSLALKVVTIFPDFSTLLSLSMCPRKPLNVINKGQDRGSSLGYAGNQKLLHSREHFTRNSMGTLLGQGPPEQLLEAH

--------------------------------------------------------------
>87428_87428_7_STIP1-PAK1_STIP1_chr11_63953742_ENST00000538945_PAK1_chr11_77043912_ENST00000528203_length(transcript)=591nt_BP=67nt
GGTTGGGAACGCGGAGCGGACGGATTCGATTCAACGGGGTTCCGGACCGCGCTGCGCTATGGAGCAGGCCTTGTACCTCATTGCCACCAA
TGGGACCCCAGAACTTCAGAACCCAGAGAAGCTGTCAGCTATCTTCCGGGACTTTCTGAACCGCTGTCTCGAGATGGATGTGGAGAAGAG
AGGTTCAGCTAAAGAGCTGCTACAGGTGAGAAAACTGAGGTTTCAAGTGTTTAGTAACTTTTCCATGATAGCTGCATCAATTCCTGAAGA
TTGCCAAGCCCCTCTCCAGCCTCACTCCACTGATTGCTGCAGCTAAGGAGGCAACAAAGAACAATCACTAAAACCACACTCACCCCAGCC
TCATTGTGCCAAGCCTTCTGTGAGATAAATGCACATTTCAGAAATTCCAACTCCTGATGCCCTCTTCTCCTTGCCTTGCTTCTCCCATTT
CCTGATCTAGCACTCCTCAAGACTTTGATCCTTGGAAACCGTGTGTCCAGCATTGAAGAGAACTGCAACTGAATGACTAATCAGATGATG

>87428_87428_7_STIP1-PAK1_STIP1_chr11_63953742_ENST00000538945_PAK1_chr11_77043912_ENST00000528203_length(amino acids)=95AA_BP=
MQFSSMLDTRFPRIKVLRSARSGNGRSKARRRGHQELEFLKCAFISQKAWHNEAGVSVVLVIVLCCLLSCSNQWSEAGEGLGNLQELMQL

--------------------------------------------------------------
>87428_87428_8_STIP1-PAK1_STIP1_chr11_63953742_ENST00000538945_PAK1_chr11_77043912_ENST00000530617_length(transcript)=1343nt_BP=67nt
GGTTGGGAACGCGGAGCGGACGGATTCGATTCAACGGGGTTCCGGACCGCGCTGCGCTATGGAGCAGGCCTTGTACCTCATTGCCACCAA
TGGGACCCCAGAACTTCAGAACCCAGAGAAGCTGTCAGCTATCTTCCGGGACTTTCTGAACCGCTGTCTCGAGATGGATGTGGAGAAGAG
AGGTTCAGCTAAAGAGCTGCTACAGCACTCCTCAAGACTTTGATCCTTGGAAACCGTGTGTCCAGCATTGAAGAGAACTGCAACTGAATG
ACTAATCAGATGATGGCCATTTCTAAATAAGGAATTTCCTCCCAATTCATGGATATGAGGGTGGTTTATGATTAAGGGTTTATATAAATA
AATGTTTCTAGTCTTCCGTGTGTCAAAATCCTCACCTCCTTCATAACCATCTCCCACAATTAATTCTTGACTATATAAATTTATGGTTTG
ATAATATTATCAATTTGTAATCAATTGAGATTTCTTTAGTGCTTGCTTTTCTGTGACTCAACTGCCCAGACACCTCATTGTACTTGAAAA
CTGGAACAGCTTGGGAATGCCATGGGGTTTGATAATCTGCCAGGGACATGAAGAGGCTCAGCTTCCTGGACCATGACTTTGGCTCAGCTG
ATCCTGACATGGGAGAACAACCACATTTTTCTTTGTGTGTGCTTCTAGCAGCTGTTCGGGAGGACCTTGACCCAATAGTGTTCCCATGCT
GTTTCTTGTGAAATGCTCTCGGCTATGTAGCAGCTTTTGATTCCCTGCATACCCTAGGCTGCTGCCCCTATCCTGTCCCTTGTTTATAAC
ATTGAGAGGTTTTCTAGGGCACATACTGAGTGAGAGCAGTGTTGAGAAGTCGGGGAAAATGGTGACTACTTTTAGAGCAAGGCTGGGCAT
CAGCACCTGTCCAGCTCTACTTGTGTGATGTTTCAGGAACTCAGCCCCTTTTTCTGCCTAGGATAAGGAGCTGAAAGATTAACTTGGATC
TTCTAATGGTCCAAATCTTTTGGTCACAATAAAGAGTCTCCAAATTAGAGACTGCATGTTAGTTCTGGATGGATTTGGTGGCCTGACATG
ATACCCTGCCAGCTGTGAGGGGACCCCGTTTTTAAGATGCATGGCCAAGCTCTCTGCAAATGGAAATGCTTACACTGGGTGTTGGGGATG
TTTGCTACCTCCTGCTATTTTTGTGGTTTTGGTTCTCCCACTATGGTAGGACCCCTGGCCAGCATTGTGGCTTGTCATGTCAGCCCCATT

>87428_87428_8_STIP1-PAK1_STIP1_chr11_63953742_ENST00000538945_PAK1_chr11_77043912_ENST00000530617_length(amino acids)=112AA_BP=
MKHHTSRAGQVLMPSLALKVVTIFPDFSTLLSLSMCPRKPLNVINKGQDRGSSLGYAGNQKLLHSREHFTRNSMGTLLGQGPPEQLLEAH

--------------------------------------------------------------
>87428_87428_9_STIP1-PAK1_STIP1_chr11_63953742_ENST00000543847_PAK1_chr11_77043912_ENST00000278568_length(transcript)=646nt_BP=46nt
GGATTCGATTCAACGGGGTTCCGGACCGCGCTGCGCTATGGAGCAGGCCTTGTACCTCATTGCCACCAATGGGACCCCAGAACTTCAGAA
CCCAGAGAAGCTGTCAGCTATCTTCCGGGACTTTCTGAACCGCTGTCTCGAGATGGATGTGGAGAAGAGAGGTTCAGCTAAAGAGCTGCT
ACAGGTGAGAAAACTGAGGTTTCAAGTGTTTAGTAACTTTTCCATGATAGCTGCATCAATTCCTGAAGATTGCCAAGCCCCTCTCCAGCC
TCACTCCACTGATTGCTGCAGCTAAGGAGGCAACAAAGAACAATCACTAAAACCACACTCACCCCAGCCTCATTGTGCCAAGCCTTCTGT
GAGATAAATGCACATTTCAGAAATTCCAACTCCTGATGCCCTCTTCTCCTTGCCTTGCTTCTCCCATTTCCTGATCTAGCACTCCTCAAG
ACTTTGATCCTTGGAAACCGTGTGTCCAGCATTGAAGAGAACTGCAACTGAATGACTAATCAGATGATGGCCATTTCTAAATAAGGAATT
TCCTCCCAATTCATGGATATGAGGGTGGTTTATGATTAAGGGTTTATATAAATAAATGTTTCTAGTCTTCCGTGTGTCAAAATCCTCACC

>87428_87428_9_STIP1-PAK1_STIP1_chr11_63953742_ENST00000543847_PAK1_chr11_77043912_ENST00000278568_length(amino acids)=85AA_BP=2

--------------------------------------------------------------
>87428_87428_10_STIP1-PAK1_STIP1_chr11_63953742_ENST00000543847_PAK1_chr11_77043912_ENST00000356341_length(transcript)=1838nt_BP=46nt
GGATTCGATTCAACGGGGTTCCGGACCGCGCTGCGCTATGGAGCAGGCCTTGTACCTCATTGCCACCAATGGGACCCCAGAACTTCAGAA
CCCAGAGAAGCTGTCAGCTATCTTCCGGGACTTTCTGAACCGCTGTCTCGAGATGGATGTGGAGAAGAGAGGTTCAGCTAAAGAGCTGCT
ACAGCATCAATTCCTGAAGATTGCCAAGCCCCTCTCCAGCCTCACTCCACTGATTGCTGCAGCTAAGGAGGCAACAAAGAACAATCACTA
AAACCACACTCACCCCAGCCTCATTGTGCCAAGCCTTCTGTGAGATAAATGCACATTTCAGAAATTCCAACTCCTGATGCCCTCTTCTCC
TTGCCTTGCTTCTCCCATTTCCTGATCTAGCACTCCTCAAGACTTTGATCCTTGGAAACCGTGTGTCCAGCATTGAAGAGAACTGCAACT
GAATGACTAATCAGATGATGGCCATTTCTAAATAAGGAATTTCCTCCCAATTCATGGATATGAGGGTGGTTTATGATTAAGGGTTTATAT
AAATAAATGTTTCTAGTCTTCCGTGTGTCAAAATCCTCACCTCCTTCATAACCATCTCCCACAATTAATTCTTGACTATATAAATTTATG
GTTTGATAATATTATCAATTTGTAATCAATTGAGATTTCTTTAGTGCTTGCTTTTCTGTGACTCAACTGCCCAGACACCTCATTGTACTT
GAAAACTGGAACAGCTTGGGAATGCCATGGGGTTTGATAATCTGCCAGGGACATGAAGAGGCTCAGCTTCCTGGACCATGACTTTGGCTC
AGCTGATCCTGACATGGGAGAACAACCACATTTTTCTTTGTGTGTGCTTCTAGCAGCTGTTCGGGAGGACCTTGACCCAATAGTGTTCCC
ATGCTGTTTCTTGTGAAATGCTCTCGGCTATGTAGCAGCTTTTGATTCCCTGCATACCCTAGGCTGCTGCCCCTATCCTGTCCCTTGTTT
ATAACATTGAGAGGTTTTCTAGGGCACATACTGAGTGAGAGCAGTGTTGAGAAGTCGGGGAAAATGGTGACTACTTTTAGAGCAAGGCTG
GGCATCAGCACCTGTCCAGCTCTACTTGTGTGATGTTTCAGGAACTCAGCCCCTTTTTCTGCCTAGGATAAGGAGCTGAAAGATTAACTT
GGATCTTCTAATGGTCCAAATCTTTTGGTCACAATAAAGAGTCTCCAAATTAGAGACTGCATGTTAGTTCTGGATGGATTTGGTGGCCTG
ACATGATACCCTGCCAGCTGTGAGGGGACCCCGTTTTTAAGATGCATGGCCAAGCTCTCTGCAAATGGAAATGCTTACACTGGGTGTTGG
GGATGTTTGCTACCTCCTGCTATTTTTGTGGTTTTGGTTCTCCCACTATGGTAGGACCCCTGGCCAGCATTGTGGCTTGTCATGTCAGCC
CCATTGACTACCTTCTCATGCTCTGAGGTACTACTGCCTCTGCAGCACAAATTTCTATTTCTGTCAATAAAAGGAGATGAAAATATTCTA
TTGGAGTATGCCTTTCTTTTTTCTCTTCGTTTTTTCTTTCCTTTTCTAATTTTTTATATGAAATAATGAGTAGTTTCTTCCTGAACCATT
TGAGAGTGGTAAGTTGCAGATAGAATGCCCCTTTACCACTATATACCTGAATGTGTATTCTTTCTTTTTAACACTTTTATTTTAAATATA
AATTAAGAGAAATGGGCCAAAACCATTTGTATTGTTTAAAGAATAATTATAAACACACTTGTATCCACCAAATCAAGAAATGGAACACTG

>87428_87428_10_STIP1-PAK1_STIP1_chr11_63953742_ENST00000543847_PAK1_chr11_77043912_ENST00000356341_length(amino acids)=112AA_BP=
MKHHTSRAGQVLMPSLALKVVTIFPDFSTLLSLSMCPRKPLNVINKGQDRGSSLGYAGNQKLLHSREHFTRNSMGTLLGQGPPEQLLEAH

--------------------------------------------------------------
>87428_87428_11_STIP1-PAK1_STIP1_chr11_63953742_ENST00000543847_PAK1_chr11_77043912_ENST00000528203_length(transcript)=570nt_BP=46nt
GGATTCGATTCAACGGGGTTCCGGACCGCGCTGCGCTATGGAGCAGGCCTTGTACCTCATTGCCACCAATGGGACCCCAGAACTTCAGAA
CCCAGAGAAGCTGTCAGCTATCTTCCGGGACTTTCTGAACCGCTGTCTCGAGATGGATGTGGAGAAGAGAGGTTCAGCTAAAGAGCTGCT
ACAGGTGAGAAAACTGAGGTTTCAAGTGTTTAGTAACTTTTCCATGATAGCTGCATCAATTCCTGAAGATTGCCAAGCCCCTCTCCAGCC
TCACTCCACTGATTGCTGCAGCTAAGGAGGCAACAAAGAACAATCACTAAAACCACACTCACCCCAGCCTCATTGTGCCAAGCCTTCTGT
GAGATAAATGCACATTTCAGAAATTCCAACTCCTGATGCCCTCTTCTCCTTGCCTTGCTTCTCCCATTTCCTGATCTAGCACTCCTCAAG
ACTTTGATCCTTGGAAACCGTGTGTCCAGCATTGAAGAGAACTGCAACTGAATGACTAATCAGATGATGGCCATTTCTAAATAAGGAATT

>87428_87428_11_STIP1-PAK1_STIP1_chr11_63953742_ENST00000543847_PAK1_chr11_77043912_ENST00000528203_length(amino acids)=95AA_BP=
MQFSSMLDTRFPRIKVLRSARSGNGRSKARRRGHQELEFLKCAFISQKAWHNEAGVSVVLVIVLCCLLSCSNQWSEAGEGLGNLQELMQL

--------------------------------------------------------------
>87428_87428_12_STIP1-PAK1_STIP1_chr11_63953742_ENST00000543847_PAK1_chr11_77043912_ENST00000530617_length(transcript)=1322nt_BP=46nt
GGATTCGATTCAACGGGGTTCCGGACCGCGCTGCGCTATGGAGCAGGCCTTGTACCTCATTGCCACCAATGGGACCCCAGAACTTCAGAA
CCCAGAGAAGCTGTCAGCTATCTTCCGGGACTTTCTGAACCGCTGTCTCGAGATGGATGTGGAGAAGAGAGGTTCAGCTAAAGAGCTGCT
ACAGCACTCCTCAAGACTTTGATCCTTGGAAACCGTGTGTCCAGCATTGAAGAGAACTGCAACTGAATGACTAATCAGATGATGGCCATT
TCTAAATAAGGAATTTCCTCCCAATTCATGGATATGAGGGTGGTTTATGATTAAGGGTTTATATAAATAAATGTTTCTAGTCTTCCGTGT
GTCAAAATCCTCACCTCCTTCATAACCATCTCCCACAATTAATTCTTGACTATATAAATTTATGGTTTGATAATATTATCAATTTGTAAT
CAATTGAGATTTCTTTAGTGCTTGCTTTTCTGTGACTCAACTGCCCAGACACCTCATTGTACTTGAAAACTGGAACAGCTTGGGAATGCC
ATGGGGTTTGATAATCTGCCAGGGACATGAAGAGGCTCAGCTTCCTGGACCATGACTTTGGCTCAGCTGATCCTGACATGGGAGAACAAC
CACATTTTTCTTTGTGTGTGCTTCTAGCAGCTGTTCGGGAGGACCTTGACCCAATAGTGTTCCCATGCTGTTTCTTGTGAAATGCTCTCG
GCTATGTAGCAGCTTTTGATTCCCTGCATACCCTAGGCTGCTGCCCCTATCCTGTCCCTTGTTTATAACATTGAGAGGTTTTCTAGGGCA
CATACTGAGTGAGAGCAGTGTTGAGAAGTCGGGGAAAATGGTGACTACTTTTAGAGCAAGGCTGGGCATCAGCACCTGTCCAGCTCTACT
TGTGTGATGTTTCAGGAACTCAGCCCCTTTTTCTGCCTAGGATAAGGAGCTGAAAGATTAACTTGGATCTTCTAATGGTCCAAATCTTTT
GGTCACAATAAAGAGTCTCCAAATTAGAGACTGCATGTTAGTTCTGGATGGATTTGGTGGCCTGACATGATACCCTGCCAGCTGTGAGGG
GACCCCGTTTTTAAGATGCATGGCCAAGCTCTCTGCAAATGGAAATGCTTACACTGGGTGTTGGGGATGTTTGCTACCTCCTGCTATTTT
TGTGGTTTTGGTTCTCCCACTATGGTAGGACCCCTGGCCAGCATTGTGGCTTGTCATGTCAGCCCCATTGACTACCTTCTCATGCTCTGA

>87428_87428_12_STIP1-PAK1_STIP1_chr11_63953742_ENST00000543847_PAK1_chr11_77043912_ENST00000530617_length(amino acids)=112AA_BP=
MKHHTSRAGQVLMPSLALKVVTIFPDFSTLLSLSMCPRKPLNVINKGQDRGSSLGYAGNQKLLHSREHFTRNSMGTLLGQGPPEQLLEAH

--------------------------------------------------------------

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Fusion Gene PPI Analysis for STIP1-PAK1


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with
TgenePAK1chr11:63953742chr11:77043912ENST000002785681216132_270471.0554.0CRIPAK
TgenePAK1chr11:63953742chr11:77043912ENST000003563411215132_270471.0546.0CRIPAK


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for STIP1-PAK1


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for STIP1-PAK1


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource