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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:STK24-ANO2 (FusionGDB2 ID:87470)

Fusion Gene Summary for STK24-ANO2

check button Fusion gene summary
Fusion gene informationFusion gene name: STK24-ANO2
Fusion gene ID: 87470
HgeneTgene
Gene symbol

STK24

ANO2

Gene ID

8428

57101

Gene nameserine/threonine kinase 24anoctamin 2
SynonymsHEL-S-95|MST3|MST3B|STE20|STK3C12orf3|TMEM16B
Cytomap

13q32.2

12p13.31

Type of geneprotein-codingprotein-coding
Descriptionserine/threonine-protein kinase 24STE20-like kinase 3STE20-like kinase MST3epididymis secretory protein Li 95mammalian STE20-like protein kinase 3serine/threonine kinase 24 (STE20 homolog, yeast)sterile 20-like kinase 3anoctamin-2anoctamin 2, calcium activated chloride channeltransmembrane protein 16B (eight membrane-spanning domains)
Modification date2020031320200329
UniProtAcc.

Q9NQ90

Ensembl transtripts involved in fusion geneENST00000376547, ENST00000397517, 
ENST00000539966, ENST00000481288, 
ENST00000538154, ENST00000327087, 
ENST00000356134, ENST00000546188, 
Fusion gene scores* DoF score18 X 9 X 11=178212 X 11 X 8=1056
# samples 2515
** MAII scorelog2(25/1782*10)=-2.83349733685984
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(15/1056*10)=-2.81557542886257
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: STK24 [Title/Abstract] AND ANO2 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointSTK24(99171496)-ANO2(5756967), # samples:1
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneSTK24

GO:0006468

protein phosphorylation

19604147

HgeneSTK24

GO:0042542

response to hydrogen peroxide

22291017

HgeneSTK24

GO:0046777

protein autophosphorylation

17046825|17657516


check buttonFusion gene breakpoints across STK24 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across ANO2 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4Non-Cancer61NSTK24chr13

99171496

-ANO2chr12

5756967

-


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Fusion Gene ORF analysis for STK24-ANO2

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-5UTRENST00000376547ENST00000538154STK24chr13

99171496

-ANO2chr12

5756967

-
5CDS-5UTRENST00000397517ENST00000538154STK24chr13

99171496

-ANO2chr12

5756967

-
5CDS-5UTRENST00000539966ENST00000538154STK24chr13

99171496

-ANO2chr12

5756967

-
5UTR-3CDSENST00000481288ENST00000327087STK24chr13

99171496

-ANO2chr12

5756967

-
5UTR-3CDSENST00000481288ENST00000356134STK24chr13

99171496

-ANO2chr12

5756967

-
5UTR-3CDSENST00000481288ENST00000546188STK24chr13

99171496

-ANO2chr12

5756967

-
5UTR-5UTRENST00000481288ENST00000538154STK24chr13

99171496

-ANO2chr12

5756967

-
In-frameENST00000376547ENST00000327087STK24chr13

99171496

-ANO2chr12

5756967

-
In-frameENST00000376547ENST00000356134STK24chr13

99171496

-ANO2chr12

5756967

-
In-frameENST00000376547ENST00000546188STK24chr13

99171496

-ANO2chr12

5756967

-
In-frameENST00000397517ENST00000327087STK24chr13

99171496

-ANO2chr12

5756967

-
In-frameENST00000397517ENST00000356134STK24chr13

99171496

-ANO2chr12

5756967

-
In-frameENST00000397517ENST00000546188STK24chr13

99171496

-ANO2chr12

5756967

-
In-frameENST00000539966ENST00000327087STK24chr13

99171496

-ANO2chr12

5756967

-
In-frameENST00000539966ENST00000356134STK24chr13

99171496

-ANO2chr12

5756967

-
In-frameENST00000539966ENST00000546188STK24chr13

99171496

-ANO2chr12

5756967

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000397517STK24chr1399171496-ENST00000327087ANO2chr125756967-2450350681801577
ENST00000397517STK24chr1399171496-ENST00000546188ANO2chr125756967-2447350681801577
ENST00000397517STK24chr1399171496-ENST00000356134ANO2chr125756967-2447350681801577
ENST00000539966STK24chr1399171496-ENST00000327087ANO2chr125756967-2455355731806577
ENST00000539966STK24chr1399171496-ENST00000546188ANO2chr125756967-2452355731806577
ENST00000539966STK24chr1399171496-ENST00000356134ANO2chr125756967-2452355731806577
ENST00000376547STK24chr1399171496-ENST00000327087ANO2chr125756967-25554551311906591
ENST00000376547STK24chr1399171496-ENST00000546188ANO2chr125756967-25524551311906591
ENST00000376547STK24chr1399171496-ENST00000356134ANO2chr125756967-25524551311906591

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000397517ENST00000327087STK24chr1399171496-ANO2chr125756967-0.0050728650.99492717
ENST00000397517ENST00000546188STK24chr1399171496-ANO2chr125756967-0.0050794590.99492055
ENST00000397517ENST00000356134STK24chr1399171496-ANO2chr125756967-0.0050794590.99492055
ENST00000539966ENST00000327087STK24chr1399171496-ANO2chr125756967-0.0050731830.9949268
ENST00000539966ENST00000546188STK24chr1399171496-ANO2chr125756967-0.0050867370.9949132
ENST00000539966ENST00000356134STK24chr1399171496-ANO2chr125756967-0.0050867370.9949132
ENST00000376547ENST00000327087STK24chr1399171496-ANO2chr125756967-0.0022710220.997729
ENST00000376547ENST00000546188STK24chr1399171496-ANO2chr125756967-0.0022712140.99772877
ENST00000376547ENST00000356134STK24chr1399171496-ANO2chr125756967-0.0022712140.99772877

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Fusion Genomic Features for STK24-ANO2


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for STK24-ANO2


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr13:99171496/chr12:5756967)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
.ANO2

Q9NQ90

FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Calcium-activated chloride channel (CaCC) which may play a role in olfactory signal transduction. Odorant molecules bind to odor-sensing receptors (OSRs), leading to an increase in calcium entry that activates CaCC current which amplifies the depolarization of the OSR cells, ANO2 seems to be the underlying chloride channel involved in this process. May mediate light perception amplification in retina. {ECO:0000269|PubMed:19474308, ECO:0000269|PubMed:20056604, ECO:0000269|PubMed:21890523, ECO:0000269|PubMed:21984732}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneSTK24chr13:99171496chr12:5756967ENST00000376547-21142_50103444.0Nucleotide bindingNote=ATP
HgeneSTK24chr13:99171496chr12:5756967ENST00000397517-21142_5091432.0Nucleotide bindingNote=ATP
TgeneANO2chr13:99171496chr12:5756967ENST0000032708714261001_1003515999.0MotifNote=DLG4 binding (PDZ)
TgeneANO2chr13:99171496chr12:5756967ENST0000035613415271001_10035161000.0MotifNote=DLG4 binding (PDZ)
TgeneANO2chr13:99171496chr12:5756967ENST000003270871426560_582515999.0Topological domainExtracellular
TgeneANO2chr13:99171496chr12:5756967ENST000003270871426604_623515999.0Topological domainCytoplasmic
TgeneANO2chr13:99171496chr12:5756967ENST000003270871426645_748515999.0Topological domainExtracellular
TgeneANO2chr13:99171496chr12:5756967ENST000003270871426770_801515999.0Topological domainCytoplasmic
TgeneANO2chr13:99171496chr12:5756967ENST000003270871426823_907515999.0Topological domainExtracellular
TgeneANO2chr13:99171496chr12:5756967ENST000003270871426929_1003515999.0Topological domainCytoplasmic
TgeneANO2chr13:99171496chr12:5756967ENST000003561341527560_5825161000.0Topological domainExtracellular
TgeneANO2chr13:99171496chr12:5756967ENST000003561341527604_6235161000.0Topological domainCytoplasmic
TgeneANO2chr13:99171496chr12:5756967ENST000003561341527645_7485161000.0Topological domainExtracellular
TgeneANO2chr13:99171496chr12:5756967ENST000003561341527770_8015161000.0Topological domainCytoplasmic
TgeneANO2chr13:99171496chr12:5756967ENST000003561341527823_9075161000.0Topological domainExtracellular
TgeneANO2chr13:99171496chr12:5756967ENST000003561341527929_10035161000.0Topological domainCytoplasmic
TgeneANO2chr13:99171496chr12:5756967ENST000003270871426539_559515999.0TransmembraneHelical
TgeneANO2chr13:99171496chr12:5756967ENST000003270871426583_603515999.0TransmembraneHelical
TgeneANO2chr13:99171496chr12:5756967ENST000003270871426624_644515999.0TransmembraneHelical
TgeneANO2chr13:99171496chr12:5756967ENST000003270871426749_769515999.0TransmembraneHelical
TgeneANO2chr13:99171496chr12:5756967ENST000003270871426802_822515999.0TransmembraneHelical
TgeneANO2chr13:99171496chr12:5756967ENST000003270871426908_928515999.0TransmembraneHelical
TgeneANO2chr13:99171496chr12:5756967ENST000003561341527539_5595161000.0TransmembraneHelical
TgeneANO2chr13:99171496chr12:5756967ENST000003561341527583_6035161000.0TransmembraneHelical
TgeneANO2chr13:99171496chr12:5756967ENST000003561341527624_6445161000.0TransmembraneHelical
TgeneANO2chr13:99171496chr12:5756967ENST000003561341527749_7695161000.0TransmembraneHelical
TgeneANO2chr13:99171496chr12:5756967ENST000003561341527802_8225161000.0TransmembraneHelical
TgeneANO2chr13:99171496chr12:5756967ENST000003561341527908_9285161000.0TransmembraneHelical

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneSTK24chr13:99171496chr12:5756967ENST00000376547-21136_286103444.0DomainProtein kinase
HgeneSTK24chr13:99171496chr12:5756967ENST00000397517-21136_28691432.0DomainProtein kinase
HgeneSTK24chr13:99171496chr12:5756967ENST00000376547-211278_292103444.0MotifNote=Bipartite nuclear localization signal
HgeneSTK24chr13:99171496chr12:5756967ENST00000376547-211335_386103444.0MotifNote=Nuclear export signal (NES)
HgeneSTK24chr13:99171496chr12:5756967ENST00000397517-211278_29291432.0MotifNote=Bipartite nuclear localization signal
HgeneSTK24chr13:99171496chr12:5756967ENST00000397517-211335_38691432.0MotifNote=Nuclear export signal (NES)
HgeneSTK24chr13:99171496chr12:5756967ENST00000376547-211112_114103444.0Nucleotide bindingNote=ATP
HgeneSTK24chr13:99171496chr12:5756967ENST00000397517-211112_11491432.0Nucleotide bindingNote=ATP
TgeneANO2chr13:99171496chr12:5756967ENST0000032708714261_365515999.0Topological domainCytoplasmic
TgeneANO2chr13:99171496chr12:5756967ENST000003270871426387_434515999.0Topological domainExtracellular
TgeneANO2chr13:99171496chr12:5756967ENST000003270871426456_538515999.0Topological domainCytoplasmic
TgeneANO2chr13:99171496chr12:5756967ENST0000035613415271_3655161000.0Topological domainCytoplasmic
TgeneANO2chr13:99171496chr12:5756967ENST000003561341527387_4345161000.0Topological domainExtracellular
TgeneANO2chr13:99171496chr12:5756967ENST000003561341527456_5385161000.0Topological domainCytoplasmic
TgeneANO2chr13:99171496chr12:5756967ENST000003270871426366_386515999.0TransmembraneHelical
TgeneANO2chr13:99171496chr12:5756967ENST000003270871426435_455515999.0TransmembraneHelical
TgeneANO2chr13:99171496chr12:5756967ENST000003561341527366_3865161000.0TransmembraneHelical
TgeneANO2chr13:99171496chr12:5756967ENST000003561341527435_4555161000.0TransmembraneHelical


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Fusion Gene Sequence for STK24-ANO2


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>87470_87470_1_STK24-ANO2_STK24_chr13_99171496_ENST00000376547_ANO2_chr12_5756967_ENST00000327087_length(transcript)=2555nt_BP=455nt
TTTGGGTTAGGGAGAGTGCTTTCGTTTGTTTTAAATGGGAGAAACTGGAGCATGTTGCCAAGGGCAGAGAGCCAGCAGAGAGGGGTGAAT
GGAAGAAGGAGCGAGAAGGGGGTTACTGACGAAGCCTTATCCTGGAGGAGAGAAGGATGGACTCCAGAGCCCAGCTTTGGGGACTGGCCT
TGAATAAAAGGAGGGCCACTCTACCTCATCCTGGAGGGAGCACGAACCTAAAGGCAGACCCAGAAGAGCTTTTTACAAAACTAGAGAAAA
TTGGGAAGGGCTCCTTTGGAGAGGTGTTCAAAGGCATTGACAATCGGACTCAGAAAGTGGTTGCCATAAAGATCATTGATCTGGAAGAAG
CTGAAGATGAGATAGAGGACATTCAACAAGAAATCACAGTGCTGAGTCAGTGTGACAGTCCATATGTAACCAAATATTATGGATCCTATC
TGAAGGATGATGAAGATAAACTGACCTGGAAGGATCGTTTCCCAGGTTACCTGATGAACTTTGCCTCCATCTTATTCATGATTGCCCTGA
CATTCTCAATCGTCTTTGGGGTGATAGTGTATCGAATAACAACTGCAGCCGCTCTGTCTCTCAATAAGGCTACACGCTCCAATGTCCGGG
TGACAGTGACAGCAACAGCAGTCATCATCAACCTCGTGGTCATCCTCATCCTGGACGAGATCTACGGCGCTGTGGCCAAGTGGCTCACCA
AAATTGAGGTTCCGAAAACAGAACAGACTTTTGAAGAGCGCCTGATCCTCAAAGCTTTCTTGCTCAAGTTTGTCAATGCCTACTCCCCCA
TCTTCTATGTGGCCTTTTTCAAAGGGAGGTTTGTGGGCAGGCCTGGAAGCTACGTCTATGTATTCGATGGTTACCGCATGGAAGAGTGTG
CTCCAGGGGGCTGTCTCATGGAGCTCTGCATTCAGCTCAGCATCATCATGTTGGGGAAGCAGTTGATCCAGAACAACATCTTTGAGATTG
GAGTCCCGAAGCTAAAGAAACTATTTCGAAAGCTGAAAGATGAGACCGAAGCTGGAGAAACTGACTCTGCCCATTCGAAACATCCAGAGC
AGTGGGACCTAGACTACAGCTTGGAACCATACACAGGACTGACTCCGGAGTACATGGAAATGATCATCCAGTTTGGTTTTGTCACCCTCT
TCGTGGCCTCCTTTCCCCTGGCACCTGTGTTTGCCCTCCTCAACAACGTCATTGAAGTGCGGCTCGATGCAAAGAAGTTTGTTACAGAGC
TGAGACGGCCGGATGCTGTAAGAACCAAAGATATCGGAATCTGGTTTGACATTCTCTCTGGAATTGGCAAGTTCTCTGTTATCAGCAACG
CTTTTGTCATTGCGATCACCTCCGACTTTATCCCCCGCCTGGTGTACCAGTACTCCTACAGTCACAATGGGACTCTGCACGGCTTTGTCA
ACCACACCCTCTCCTTTTTCAACGTCAGCCAGCTGAAGGAGGGGACGCAGCCAGAAAACTCACAGTTTGACCAGGAGGTTCAGTTCTGCA
GGTTTAAGGATTACCGAGAGCCGCCATGGGCCCCGAACCCTTATGAGTTTTCGAAACAGTACTGGTTTATTCTGTCCGCCCGTCTGGCTT
TTGTCATAATCTTCCAGAACCTCGTGATGTTCCTGAGCGTCCTCGTGGACTGGATGATTCCAGACATCCCCACGGACATCAGCGACCAGA
TCAAGAAAGAGAAGAGCTTATTAGTGGATTTCTTCCTGAAAGAGGAGCATGAGAAGCTCAAGCTGATGGATGAGCCGGCTCTGAGGAGCC
CAGGAGGTGGGGATCGAAGCAGGAGCCGGGCAGCCAGCTCAGCACCTTCAGGCCAAAGCCAGCTGGGCAGCATGATGTCGTCAGGCTCTC
AGCACACCAATGTGTGAGCAGTTCAGCCTGCAGCAGAGGAGGGCACGGCAGCAGAGACACGCACATGCACGTAAGCATGTTCCTACACCC
ACATGGCGTGCTGTCTGTCTGCAGGGGCCTGGCTTGATGGGGTCTTGAAGAGGGGGCAGTGTGTAAAAAGAAAGAGCCTGACAGAATGAG
TGTAGGAAGGAAGAGAAATGATGCTACATCTCAGAAACTTCAAGCTTAAGTTTCTTTTAGGTCCCCTTTTAAGCTGCATCCTTTTGAGGG
ATTGGAACCCCACTGGGGTCTCTCCACCCCAGAGTCTCAGGCACCGCGAGCATTCCCATGTACCCTGGGGCACCCTCTTGTACTTCACCA
TCATTTCTGACTTTGACCAGCTGTAAGAGAAATGCAGTCAGGAGCACAGCATCCCCTACTTACTATCACTACAAGAAAACTGAGTCACTT
GCAGTGGGGCTGCCACAGTCTCAGCAGATGCAAATTAAGTTACAAGGCTGAATGGTGCAGCCGCTGGACCTGATAGTAAGGTGCAAAGGT
CCAAACCTGGGCTTGTCTCCACTTCACGTCACAAAAACGTTTGGAGCTAAATGCAGATAACCATCATTTTATGAAAGTTCAGATTTAAAA

>87470_87470_1_STK24-ANO2_STK24_chr13_99171496_ENST00000376547_ANO2_chr12_5756967_ENST00000327087_length(amino acids)=591AA_BP=108
MEERRMDSRAQLWGLALNKRRATLPHPGGSTNLKADPEELFTKLEKIGKGSFGEVFKGIDNRTQKVVAIKIIDLEEAEDEIEDIQQEITV
LSQCDSPYVTKYYGSYLKDDEDKLTWKDRFPGYLMNFASILFMIALTFSIVFGVIVYRITTAAALSLNKATRSNVRVTVTATAVIINLVV
ILILDEIYGAVAKWLTKIEVPKTEQTFEERLILKAFLLKFVNAYSPIFYVAFFKGRFVGRPGSYVYVFDGYRMEECAPGGCLMELCIQLS
IIMLGKQLIQNNIFEIGVPKLKKLFRKLKDETEAGETDSAHSKHPEQWDLDYSLEPYTGLTPEYMEMIIQFGFVTLFVASFPLAPVFALL
NNVIEVRLDAKKFVTELRRPDAVRTKDIGIWFDILSGIGKFSVISNAFVIAITSDFIPRLVYQYSYSHNGTLHGFVNHTLSFFNVSQLKE
GTQPENSQFDQEVQFCRFKDYREPPWAPNPYEFSKQYWFILSARLAFVIIFQNLVMFLSVLVDWMIPDIPTDISDQIKKEKSLLVDFFLK

--------------------------------------------------------------
>87470_87470_2_STK24-ANO2_STK24_chr13_99171496_ENST00000376547_ANO2_chr12_5756967_ENST00000356134_length(transcript)=2552nt_BP=455nt
TTTGGGTTAGGGAGAGTGCTTTCGTTTGTTTTAAATGGGAGAAACTGGAGCATGTTGCCAAGGGCAGAGAGCCAGCAGAGAGGGGTGAAT
GGAAGAAGGAGCGAGAAGGGGGTTACTGACGAAGCCTTATCCTGGAGGAGAGAAGGATGGACTCCAGAGCCCAGCTTTGGGGACTGGCCT
TGAATAAAAGGAGGGCCACTCTACCTCATCCTGGAGGGAGCACGAACCTAAAGGCAGACCCAGAAGAGCTTTTTACAAAACTAGAGAAAA
TTGGGAAGGGCTCCTTTGGAGAGGTGTTCAAAGGCATTGACAATCGGACTCAGAAAGTGGTTGCCATAAAGATCATTGATCTGGAAGAAG
CTGAAGATGAGATAGAGGACATTCAACAAGAAATCACAGTGCTGAGTCAGTGTGACAGTCCATATGTAACCAAATATTATGGATCCTATC
TGAAGGATGATGAAGATAAACTGACCTGGAAGGATCGTTTCCCAGGTTACCTGATGAACTTTGCCTCCATCTTATTCATGATTGCCCTGA
CATTCTCAATCGTCTTTGGGGTGATAGTGTATCGAATAACAACTGCAGCCGCTCTGTCTCTCAATAAGGCTACACGCTCCAATGTCCGGG
TGACAGTGACAGCAACAGCAGTCATCATCAACCTCGTGGTCATCCTCATCCTGGACGAGATCTACGGCGCTGTGGCCAAGTGGCTCACCA
AAATTGAGGTTCCGAAAACAGAACAGACTTTTGAAGAGCGCCTGATCCTCAAAGCTTTCTTGCTCAAGTTTGTCAATGCCTACTCCCCCA
TCTTCTATGTGGCCTTTTTCAAAGGGAGGTTTGTGGGCAGGCCTGGAAGCTACGTCTATGTATTCGATGGTTACCGCATGGAAGAGTGTG
CTCCAGGGGGCTGTCTCATGGAGCTCTGCATTCAGCTCAGCATCATCATGTTGGGGAAGCAGTTGATCCAGAACAACATCTTTGAGATTG
GAGTCCCGAAGCTAAAGAAACTATTTCGAAAGCTGAAAGATGAGACCGAAGCTGGAGAAACTGACTCTGCCCATTCGAAACATCCAGAGC
AGTGGGACCTAGACTACAGCTTGGAACCATACACAGGACTGACTCCGGAGTACATGGAAATGATCATCCAGTTTGGTTTTGTCACCCTCT
TCGTGGCCTCCTTTCCCCTGGCACCTGTGTTTGCCCTCCTCAACAACGTCATTGAAGTGCGGCTCGATGCAAAGAAGTTTGTTACAGAGC
TGAGACGGCCGGATGCTGTAAGAACCAAAGATATCGGAATCTGGTTTGACATTCTCTCTGGAATTGGCAAGTTCTCTGTTATCAGCAACG
CTTTTGTCATTGCGATCACCTCCGACTTTATCCCCCGCCTGGTGTACCAGTACTCCTACAGTCACAATGGGACTCTGCACGGCTTTGTCA
ACCACACCCTCTCCTTTTTCAACGTCAGCCAGCTGAAGGAGGGGACGCAGCCAGAAAACTCACAGTTTGACCAGGAGGTTCAGTTCTGCA
GGTTTAAGGATTACCGAGAGCCGCCATGGGCCCCGAACCCTTATGAGTTTTCGAAACAGTACTGGTTTATTCTGTCCGCCCGTCTGGCTT
TTGTCATAATCTTCCAGAACCTCGTGATGTTCCTGAGCGTCCTCGTGGACTGGATGATTCCAGACATCCCCACGGACATCAGCGACCAGA
TCAAGAAAGAGAAGAGCTTATTAGTGGATTTCTTCCTGAAAGAGGAGCATGAGAAGCTCAAGCTGATGGATGAGCCGGCTCTGAGGAGCC
CAGGAGGTGGGGATCGAAGCAGGAGCCGGGCAGCCAGCTCAGCACCTTCAGGCCAAAGCCAGCTGGGCAGCATGATGTCGTCAGGCTCTC
AGCACACCAATGTGTGAGCAGTTCAGCCTGCAGCAGAGGAGGGCACGGCAGCAGAGACACGCACATGCACGTAAGCATGTTCCTACACCC
ACATGGCGTGCTGTCTGTCTGCAGGGGCCTGGCTTGATGGGGTCTTGAAGAGGGGGCAGTGTGTAAAAAGAAAGAGCCTGACAGAATGAG
TGTAGGAAGGAAGAGAAATGATGCTACATCTCAGAAACTTCAAGCTTAAGTTTCTTTTAGGTCCCCTTTTAAGCTGCATCCTTTTGAGGG
ATTGGAACCCCACTGGGGTCTCTCCACCCCAGAGTCTCAGGCACCGCGAGCATTCCCATGTACCCTGGGGCACCCTCTTGTACTTCACCA
TCATTTCTGACTTTGACCAGCTGTAAGAGAAATGCAGTCAGGAGCACAGCATCCCCTACTTACTATCACTACAAGAAAACTGAGTCACTT
GCAGTGGGGCTGCCACAGTCTCAGCAGATGCAAATTAAGTTACAAGGCTGAATGGTGCAGCCGCTGGACCTGATAGTAAGGTGCAAAGGT
CCAAACCTGGGCTTGTCTCCACTTCACGTCACAAAAACGTTTGGAGCTAAATGCAGATAACCATCATTTTATGAAAGTTCAGATTTAAAA

>87470_87470_2_STK24-ANO2_STK24_chr13_99171496_ENST00000376547_ANO2_chr12_5756967_ENST00000356134_length(amino acids)=591AA_BP=108
MEERRMDSRAQLWGLALNKRRATLPHPGGSTNLKADPEELFTKLEKIGKGSFGEVFKGIDNRTQKVVAIKIIDLEEAEDEIEDIQQEITV
LSQCDSPYVTKYYGSYLKDDEDKLTWKDRFPGYLMNFASILFMIALTFSIVFGVIVYRITTAAALSLNKATRSNVRVTVTATAVIINLVV
ILILDEIYGAVAKWLTKIEVPKTEQTFEERLILKAFLLKFVNAYSPIFYVAFFKGRFVGRPGSYVYVFDGYRMEECAPGGCLMELCIQLS
IIMLGKQLIQNNIFEIGVPKLKKLFRKLKDETEAGETDSAHSKHPEQWDLDYSLEPYTGLTPEYMEMIIQFGFVTLFVASFPLAPVFALL
NNVIEVRLDAKKFVTELRRPDAVRTKDIGIWFDILSGIGKFSVISNAFVIAITSDFIPRLVYQYSYSHNGTLHGFVNHTLSFFNVSQLKE
GTQPENSQFDQEVQFCRFKDYREPPWAPNPYEFSKQYWFILSARLAFVIIFQNLVMFLSVLVDWMIPDIPTDISDQIKKEKSLLVDFFLK

--------------------------------------------------------------
>87470_87470_3_STK24-ANO2_STK24_chr13_99171496_ENST00000376547_ANO2_chr12_5756967_ENST00000546188_length(transcript)=2552nt_BP=455nt
TTTGGGTTAGGGAGAGTGCTTTCGTTTGTTTTAAATGGGAGAAACTGGAGCATGTTGCCAAGGGCAGAGAGCCAGCAGAGAGGGGTGAAT
GGAAGAAGGAGCGAGAAGGGGGTTACTGACGAAGCCTTATCCTGGAGGAGAGAAGGATGGACTCCAGAGCCCAGCTTTGGGGACTGGCCT
TGAATAAAAGGAGGGCCACTCTACCTCATCCTGGAGGGAGCACGAACCTAAAGGCAGACCCAGAAGAGCTTTTTACAAAACTAGAGAAAA
TTGGGAAGGGCTCCTTTGGAGAGGTGTTCAAAGGCATTGACAATCGGACTCAGAAAGTGGTTGCCATAAAGATCATTGATCTGGAAGAAG
CTGAAGATGAGATAGAGGACATTCAACAAGAAATCACAGTGCTGAGTCAGTGTGACAGTCCATATGTAACCAAATATTATGGATCCTATC
TGAAGGATGATGAAGATAAACTGACCTGGAAGGATCGTTTCCCAGGTTACCTGATGAACTTTGCCTCCATCTTATTCATGATTGCCCTGA
CATTCTCAATCGTCTTTGGGGTGATAGTGTATCGAATAACAACTGCAGCCGCTCTGTCTCTCAATAAGGCTACACGCTCCAATGTCCGGG
TGACAGTGACAGCAACAGCAGTCATCATCAACCTCGTGGTCATCCTCATCCTGGACGAGATCTACGGCGCTGTGGCCAAGTGGCTCACCA
AAATTGAGGTTCCGAAAACAGAACAGACTTTTGAAGAGCGCCTGATCCTCAAAGCTTTCTTGCTCAAGTTTGTCAATGCCTACTCCCCCA
TCTTCTATGTGGCCTTTTTCAAAGGGAGGTTTGTGGGCAGGCCTGGAAGCTACGTCTATGTATTCGATGGTTACCGCATGGAAGAGTGTG
CTCCAGGGGGCTGTCTCATGGAGCTCTGCATTCAGCTCAGCATCATCATGTTGGGGAAGCAGTTGATCCAGAACAACATCTTTGAGATTG
GAGTCCCGAAGCTAAAGAAACTATTTCGAAAGCTGAAAGATGAGACCGAAGCTGGAGAAACTGACTCTGCCCATTCGAAACATCCAGAGC
AGTGGGACCTAGACTACAGCTTGGAACCATACACAGGACTGACTCCGGAGTACATGGAAATGATCATCCAGTTTGGTTTTGTCACCCTCT
TCGTGGCCTCCTTTCCCCTGGCACCTGTGTTTGCCCTCCTCAACAACGTCATTGAAGTGCGGCTCGATGCAAAGAAGTTTGTTACAGAGC
TGAGACGGCCGGATGCTGTAAGAACCAAAGATATCGGAATCTGGTTTGACATTCTCTCTGGAATTGGCAAGTTCTCTGTTATCAGCAACG
CTTTTGTCATTGCGATCACCTCCGACTTTATCCCCCGCCTGGTGTACCAGTACTCCTACAGTCACAATGGGACTCTGCACGGCTTTGTCA
ACCACACCCTCTCCTTTTTCAACGTCAGCCAGCTGAAGGAGGGGACGCAGCCAGAAAACTCACAGTTTGACCAGGAGGTTCAGTTCTGCA
GGTTTAAGGATTACCGAGAGCCGCCATGGGCCCCGAACCCTTATGAGTTTTCGAAACAGTACTGGTTTATTCTGTCCGCCCGTCTGGCTT
TTGTCATAATCTTCCAGAACCTCGTGATGTTCCTGAGCGTCCTCGTGGACTGGATGATTCCAGACATCCCCACGGACATCAGCGACCAGA
TCAAGAAAGAGAAGAGCTTATTAGTGGATTTCTTCCTGAAAGAGGAGCATGAGAAGCTCAAGCTGATGGATGAGCCGGCTCTGAGGAGCC
CAGGAGGTGGGGATCGAAGCAGGAGCCGGGCAGCCAGCTCAGCACCTTCAGGCCAAAGCCAGCTGGGCAGCATGATGTCGTCAGGCTCTC
AGCACACCAATGTGTGAGCAGTTCAGCCTGCAGCAGAGGAGGGCACGGCAGCAGAGACACGCACATGCACGTAAGCATGTTCCTACACCC
ACATGGCGTGCTGTCTGTCTGCAGGGGCCTGGCTTGATGGGGTCTTGAAGAGGGGGCAGTGTGTAAAAAGAAAGAGCCTGACAGAATGAG
TGTAGGAAGGAAGAGAAATGATGCTACATCTCAGAAACTTCAAGCTTAAGTTTCTTTTAGGTCCCCTTTTAAGCTGCATCCTTTTGAGGG
ATTGGAACCCCACTGGGGTCTCTCCACCCCAGAGTCTCAGGCACCGCGAGCATTCCCATGTACCCTGGGGCACCCTCTTGTACTTCACCA
TCATTTCTGACTTTGACCAGCTGTAAGAGAAATGCAGTCAGGAGCACAGCATCCCCTACTTACTATCACTACAAGAAAACTGAGTCACTT
GCAGTGGGGCTGCCACAGTCTCAGCAGATGCAAATTAAGTTACAAGGCTGAATGGTGCAGCCGCTGGACCTGATAGTAAGGTGCAAAGGT
CCAAACCTGGGCTTGTCTCCACTTCACGTCACAAAAACGTTTGGAGCTAAATGCAGATAACCATCATTTTATGAAAGTTCAGATTTAAAA

>87470_87470_3_STK24-ANO2_STK24_chr13_99171496_ENST00000376547_ANO2_chr12_5756967_ENST00000546188_length(amino acids)=591AA_BP=108
MEERRMDSRAQLWGLALNKRRATLPHPGGSTNLKADPEELFTKLEKIGKGSFGEVFKGIDNRTQKVVAIKIIDLEEAEDEIEDIQQEITV
LSQCDSPYVTKYYGSYLKDDEDKLTWKDRFPGYLMNFASILFMIALTFSIVFGVIVYRITTAAALSLNKATRSNVRVTVTATAVIINLVV
ILILDEIYGAVAKWLTKIEVPKTEQTFEERLILKAFLLKFVNAYSPIFYVAFFKGRFVGRPGSYVYVFDGYRMEECAPGGCLMELCIQLS
IIMLGKQLIQNNIFEIGVPKLKKLFRKLKDETEAGETDSAHSKHPEQWDLDYSLEPYTGLTPEYMEMIIQFGFVTLFVASFPLAPVFALL
NNVIEVRLDAKKFVTELRRPDAVRTKDIGIWFDILSGIGKFSVISNAFVIAITSDFIPRLVYQYSYSHNGTLHGFVNHTLSFFNVSQLKE
GTQPENSQFDQEVQFCRFKDYREPPWAPNPYEFSKQYWFILSARLAFVIIFQNLVMFLSVLVDWMIPDIPTDISDQIKKEKSLLVDFFLK

--------------------------------------------------------------
>87470_87470_4_STK24-ANO2_STK24_chr13_99171496_ENST00000397517_ANO2_chr12_5756967_ENST00000327087_length(transcript)=2450nt_BP=350nt
GCCCGCGGGCCTCGCCGCCCCGCGCGGATCGTCGCGGCCCGGCCGTCCCGTCCCAGGAAGTGGCCGTCCTGAGCGCCATGGCTCACTCCC
CGGTGCAGTCGGGCCTGCCCGGCATGCAGAACCTAAAGGCAGACCCAGAAGAGCTTTTTACAAAACTAGAGAAAATTGGGAAGGGCTCCT
TTGGAGAGGTGTTCAAAGGCATTGACAATCGGACTCAGAAAGTGGTTGCCATAAAGATCATTGATCTGGAAGAAGCTGAAGATGAGATAG
AGGACATTCAACAAGAAATCACAGTGCTGAGTCAGTGTGACAGTCCATATGTAACCAAATATTATGGATCCTATCTGAAGGATGATGAAG
ATAAACTGACCTGGAAGGATCGTTTCCCAGGTTACCTGATGAACTTTGCCTCCATCTTATTCATGATTGCCCTGACATTCTCAATCGTCT
TTGGGGTGATAGTGTATCGAATAACAACTGCAGCCGCTCTGTCTCTCAATAAGGCTACACGCTCCAATGTCCGGGTGACAGTGACAGCAA
CAGCAGTCATCATCAACCTCGTGGTCATCCTCATCCTGGACGAGATCTACGGCGCTGTGGCCAAGTGGCTCACCAAAATTGAGGTTCCGA
AAACAGAACAGACTTTTGAAGAGCGCCTGATCCTCAAAGCTTTCTTGCTCAAGTTTGTCAATGCCTACTCCCCCATCTTCTATGTGGCCT
TTTTCAAAGGGAGGTTTGTGGGCAGGCCTGGAAGCTACGTCTATGTATTCGATGGTTACCGCATGGAAGAGTGTGCTCCAGGGGGCTGTC
TCATGGAGCTCTGCATTCAGCTCAGCATCATCATGTTGGGGAAGCAGTTGATCCAGAACAACATCTTTGAGATTGGAGTCCCGAAGCTAA
AGAAACTATTTCGAAAGCTGAAAGATGAGACCGAAGCTGGAGAAACTGACTCTGCCCATTCGAAACATCCAGAGCAGTGGGACCTAGACT
ACAGCTTGGAACCATACACAGGACTGACTCCGGAGTACATGGAAATGATCATCCAGTTTGGTTTTGTCACCCTCTTCGTGGCCTCCTTTC
CCCTGGCACCTGTGTTTGCCCTCCTCAACAACGTCATTGAAGTGCGGCTCGATGCAAAGAAGTTTGTTACAGAGCTGAGACGGCCGGATG
CTGTAAGAACCAAAGATATCGGAATCTGGTTTGACATTCTCTCTGGAATTGGCAAGTTCTCTGTTATCAGCAACGCTTTTGTCATTGCGA
TCACCTCCGACTTTATCCCCCGCCTGGTGTACCAGTACTCCTACAGTCACAATGGGACTCTGCACGGCTTTGTCAACCACACCCTCTCCT
TTTTCAACGTCAGCCAGCTGAAGGAGGGGACGCAGCCAGAAAACTCACAGTTTGACCAGGAGGTTCAGTTCTGCAGGTTTAAGGATTACC
GAGAGCCGCCATGGGCCCCGAACCCTTATGAGTTTTCGAAACAGTACTGGTTTATTCTGTCCGCCCGTCTGGCTTTTGTCATAATCTTCC
AGAACCTCGTGATGTTCCTGAGCGTCCTCGTGGACTGGATGATTCCAGACATCCCCACGGACATCAGCGACCAGATCAAGAAAGAGAAGA
GCTTATTAGTGGATTTCTTCCTGAAAGAGGAGCATGAGAAGCTCAAGCTGATGGATGAGCCGGCTCTGAGGAGCCCAGGAGGTGGGGATC
GAAGCAGGAGCCGGGCAGCCAGCTCAGCACCTTCAGGCCAAAGCCAGCTGGGCAGCATGATGTCGTCAGGCTCTCAGCACACCAATGTGT
GAGCAGTTCAGCCTGCAGCAGAGGAGGGCACGGCAGCAGAGACACGCACATGCACGTAAGCATGTTCCTACACCCACATGGCGTGCTGTC
TGTCTGCAGGGGCCTGGCTTGATGGGGTCTTGAAGAGGGGGCAGTGTGTAAAAAGAAAGAGCCTGACAGAATGAGTGTAGGAAGGAAGAG
AAATGATGCTACATCTCAGAAACTTCAAGCTTAAGTTTCTTTTAGGTCCCCTTTTAAGCTGCATCCTTTTGAGGGATTGGAACCCCACTG
GGGTCTCTCCACCCCAGAGTCTCAGGCACCGCGAGCATTCCCATGTACCCTGGGGCACCCTCTTGTACTTCACCATCATTTCTGACTTTG
ACCAGCTGTAAGAGAAATGCAGTCAGGAGCACAGCATCCCCTACTTACTATCACTACAAGAAAACTGAGTCACTTGCAGTGGGGCTGCCA
CAGTCTCAGCAGATGCAAATTAAGTTACAAGGCTGAATGGTGCAGCCGCTGGACCTGATAGTAAGGTGCAAAGGTCCAAACCTGGGCTTG
TCTCCACTTCACGTCACAAAAACGTTTGGAGCTAAATGCAGATAACCATCATTTTATGAAAGTTCAGATTTAAAATAATAAAATAAATGG

>87470_87470_4_STK24-ANO2_STK24_chr13_99171496_ENST00000397517_ANO2_chr12_5756967_ENST00000327087_length(amino acids)=577AA_BP=94
MSAMAHSPVQSGLPGMQNLKADPEELFTKLEKIGKGSFGEVFKGIDNRTQKVVAIKIIDLEEAEDEIEDIQQEITVLSQCDSPYVTKYYG
SYLKDDEDKLTWKDRFPGYLMNFASILFMIALTFSIVFGVIVYRITTAAALSLNKATRSNVRVTVTATAVIINLVVILILDEIYGAVAKW
LTKIEVPKTEQTFEERLILKAFLLKFVNAYSPIFYVAFFKGRFVGRPGSYVYVFDGYRMEECAPGGCLMELCIQLSIIMLGKQLIQNNIF
EIGVPKLKKLFRKLKDETEAGETDSAHSKHPEQWDLDYSLEPYTGLTPEYMEMIIQFGFVTLFVASFPLAPVFALLNNVIEVRLDAKKFV
TELRRPDAVRTKDIGIWFDILSGIGKFSVISNAFVIAITSDFIPRLVYQYSYSHNGTLHGFVNHTLSFFNVSQLKEGTQPENSQFDQEVQ
FCRFKDYREPPWAPNPYEFSKQYWFILSARLAFVIIFQNLVMFLSVLVDWMIPDIPTDISDQIKKEKSLLVDFFLKEEHEKLKLMDEPAL

--------------------------------------------------------------
>87470_87470_5_STK24-ANO2_STK24_chr13_99171496_ENST00000397517_ANO2_chr12_5756967_ENST00000356134_length(transcript)=2447nt_BP=350nt
GCCCGCGGGCCTCGCCGCCCCGCGCGGATCGTCGCGGCCCGGCCGTCCCGTCCCAGGAAGTGGCCGTCCTGAGCGCCATGGCTCACTCCC
CGGTGCAGTCGGGCCTGCCCGGCATGCAGAACCTAAAGGCAGACCCAGAAGAGCTTTTTACAAAACTAGAGAAAATTGGGAAGGGCTCCT
TTGGAGAGGTGTTCAAAGGCATTGACAATCGGACTCAGAAAGTGGTTGCCATAAAGATCATTGATCTGGAAGAAGCTGAAGATGAGATAG
AGGACATTCAACAAGAAATCACAGTGCTGAGTCAGTGTGACAGTCCATATGTAACCAAATATTATGGATCCTATCTGAAGGATGATGAAG
ATAAACTGACCTGGAAGGATCGTTTCCCAGGTTACCTGATGAACTTTGCCTCCATCTTATTCATGATTGCCCTGACATTCTCAATCGTCT
TTGGGGTGATAGTGTATCGAATAACAACTGCAGCCGCTCTGTCTCTCAATAAGGCTACACGCTCCAATGTCCGGGTGACAGTGACAGCAA
CAGCAGTCATCATCAACCTCGTGGTCATCCTCATCCTGGACGAGATCTACGGCGCTGTGGCCAAGTGGCTCACCAAAATTGAGGTTCCGA
AAACAGAACAGACTTTTGAAGAGCGCCTGATCCTCAAAGCTTTCTTGCTCAAGTTTGTCAATGCCTACTCCCCCATCTTCTATGTGGCCT
TTTTCAAAGGGAGGTTTGTGGGCAGGCCTGGAAGCTACGTCTATGTATTCGATGGTTACCGCATGGAAGAGTGTGCTCCAGGGGGCTGTC
TCATGGAGCTCTGCATTCAGCTCAGCATCATCATGTTGGGGAAGCAGTTGATCCAGAACAACATCTTTGAGATTGGAGTCCCGAAGCTAA
AGAAACTATTTCGAAAGCTGAAAGATGAGACCGAAGCTGGAGAAACTGACTCTGCCCATTCGAAACATCCAGAGCAGTGGGACCTAGACT
ACAGCTTGGAACCATACACAGGACTGACTCCGGAGTACATGGAAATGATCATCCAGTTTGGTTTTGTCACCCTCTTCGTGGCCTCCTTTC
CCCTGGCACCTGTGTTTGCCCTCCTCAACAACGTCATTGAAGTGCGGCTCGATGCAAAGAAGTTTGTTACAGAGCTGAGACGGCCGGATG
CTGTAAGAACCAAAGATATCGGAATCTGGTTTGACATTCTCTCTGGAATTGGCAAGTTCTCTGTTATCAGCAACGCTTTTGTCATTGCGA
TCACCTCCGACTTTATCCCCCGCCTGGTGTACCAGTACTCCTACAGTCACAATGGGACTCTGCACGGCTTTGTCAACCACACCCTCTCCT
TTTTCAACGTCAGCCAGCTGAAGGAGGGGACGCAGCCAGAAAACTCACAGTTTGACCAGGAGGTTCAGTTCTGCAGGTTTAAGGATTACC
GAGAGCCGCCATGGGCCCCGAACCCTTATGAGTTTTCGAAACAGTACTGGTTTATTCTGTCCGCCCGTCTGGCTTTTGTCATAATCTTCC
AGAACCTCGTGATGTTCCTGAGCGTCCTCGTGGACTGGATGATTCCAGACATCCCCACGGACATCAGCGACCAGATCAAGAAAGAGAAGA
GCTTATTAGTGGATTTCTTCCTGAAAGAGGAGCATGAGAAGCTCAAGCTGATGGATGAGCCGGCTCTGAGGAGCCCAGGAGGTGGGGATC
GAAGCAGGAGCCGGGCAGCCAGCTCAGCACCTTCAGGCCAAAGCCAGCTGGGCAGCATGATGTCGTCAGGCTCTCAGCACACCAATGTGT
GAGCAGTTCAGCCTGCAGCAGAGGAGGGCACGGCAGCAGAGACACGCACATGCACGTAAGCATGTTCCTACACCCACATGGCGTGCTGTC
TGTCTGCAGGGGCCTGGCTTGATGGGGTCTTGAAGAGGGGGCAGTGTGTAAAAAGAAAGAGCCTGACAGAATGAGTGTAGGAAGGAAGAG
AAATGATGCTACATCTCAGAAACTTCAAGCTTAAGTTTCTTTTAGGTCCCCTTTTAAGCTGCATCCTTTTGAGGGATTGGAACCCCACTG
GGGTCTCTCCACCCCAGAGTCTCAGGCACCGCGAGCATTCCCATGTACCCTGGGGCACCCTCTTGTACTTCACCATCATTTCTGACTTTG
ACCAGCTGTAAGAGAAATGCAGTCAGGAGCACAGCATCCCCTACTTACTATCACTACAAGAAAACTGAGTCACTTGCAGTGGGGCTGCCA
CAGTCTCAGCAGATGCAAATTAAGTTACAAGGCTGAATGGTGCAGCCGCTGGACCTGATAGTAAGGTGCAAAGGTCCAAACCTGGGCTTG
TCTCCACTTCACGTCACAAAAACGTTTGGAGCTAAATGCAGATAACCATCATTTTATGAAAGTTCAGATTTAAAATAATAAAATAAATGG

>87470_87470_5_STK24-ANO2_STK24_chr13_99171496_ENST00000397517_ANO2_chr12_5756967_ENST00000356134_length(amino acids)=577AA_BP=94
MSAMAHSPVQSGLPGMQNLKADPEELFTKLEKIGKGSFGEVFKGIDNRTQKVVAIKIIDLEEAEDEIEDIQQEITVLSQCDSPYVTKYYG
SYLKDDEDKLTWKDRFPGYLMNFASILFMIALTFSIVFGVIVYRITTAAALSLNKATRSNVRVTVTATAVIINLVVILILDEIYGAVAKW
LTKIEVPKTEQTFEERLILKAFLLKFVNAYSPIFYVAFFKGRFVGRPGSYVYVFDGYRMEECAPGGCLMELCIQLSIIMLGKQLIQNNIF
EIGVPKLKKLFRKLKDETEAGETDSAHSKHPEQWDLDYSLEPYTGLTPEYMEMIIQFGFVTLFVASFPLAPVFALLNNVIEVRLDAKKFV
TELRRPDAVRTKDIGIWFDILSGIGKFSVISNAFVIAITSDFIPRLVYQYSYSHNGTLHGFVNHTLSFFNVSQLKEGTQPENSQFDQEVQ
FCRFKDYREPPWAPNPYEFSKQYWFILSARLAFVIIFQNLVMFLSVLVDWMIPDIPTDISDQIKKEKSLLVDFFLKEEHEKLKLMDEPAL

--------------------------------------------------------------
>87470_87470_6_STK24-ANO2_STK24_chr13_99171496_ENST00000397517_ANO2_chr12_5756967_ENST00000546188_length(transcript)=2447nt_BP=350nt
GCCCGCGGGCCTCGCCGCCCCGCGCGGATCGTCGCGGCCCGGCCGTCCCGTCCCAGGAAGTGGCCGTCCTGAGCGCCATGGCTCACTCCC
CGGTGCAGTCGGGCCTGCCCGGCATGCAGAACCTAAAGGCAGACCCAGAAGAGCTTTTTACAAAACTAGAGAAAATTGGGAAGGGCTCCT
TTGGAGAGGTGTTCAAAGGCATTGACAATCGGACTCAGAAAGTGGTTGCCATAAAGATCATTGATCTGGAAGAAGCTGAAGATGAGATAG
AGGACATTCAACAAGAAATCACAGTGCTGAGTCAGTGTGACAGTCCATATGTAACCAAATATTATGGATCCTATCTGAAGGATGATGAAG
ATAAACTGACCTGGAAGGATCGTTTCCCAGGTTACCTGATGAACTTTGCCTCCATCTTATTCATGATTGCCCTGACATTCTCAATCGTCT
TTGGGGTGATAGTGTATCGAATAACAACTGCAGCCGCTCTGTCTCTCAATAAGGCTACACGCTCCAATGTCCGGGTGACAGTGACAGCAA
CAGCAGTCATCATCAACCTCGTGGTCATCCTCATCCTGGACGAGATCTACGGCGCTGTGGCCAAGTGGCTCACCAAAATTGAGGTTCCGA
AAACAGAACAGACTTTTGAAGAGCGCCTGATCCTCAAAGCTTTCTTGCTCAAGTTTGTCAATGCCTACTCCCCCATCTTCTATGTGGCCT
TTTTCAAAGGGAGGTTTGTGGGCAGGCCTGGAAGCTACGTCTATGTATTCGATGGTTACCGCATGGAAGAGTGTGCTCCAGGGGGCTGTC
TCATGGAGCTCTGCATTCAGCTCAGCATCATCATGTTGGGGAAGCAGTTGATCCAGAACAACATCTTTGAGATTGGAGTCCCGAAGCTAA
AGAAACTATTTCGAAAGCTGAAAGATGAGACCGAAGCTGGAGAAACTGACTCTGCCCATTCGAAACATCCAGAGCAGTGGGACCTAGACT
ACAGCTTGGAACCATACACAGGACTGACTCCGGAGTACATGGAAATGATCATCCAGTTTGGTTTTGTCACCCTCTTCGTGGCCTCCTTTC
CCCTGGCACCTGTGTTTGCCCTCCTCAACAACGTCATTGAAGTGCGGCTCGATGCAAAGAAGTTTGTTACAGAGCTGAGACGGCCGGATG
CTGTAAGAACCAAAGATATCGGAATCTGGTTTGACATTCTCTCTGGAATTGGCAAGTTCTCTGTTATCAGCAACGCTTTTGTCATTGCGA
TCACCTCCGACTTTATCCCCCGCCTGGTGTACCAGTACTCCTACAGTCACAATGGGACTCTGCACGGCTTTGTCAACCACACCCTCTCCT
TTTTCAACGTCAGCCAGCTGAAGGAGGGGACGCAGCCAGAAAACTCACAGTTTGACCAGGAGGTTCAGTTCTGCAGGTTTAAGGATTACC
GAGAGCCGCCATGGGCCCCGAACCCTTATGAGTTTTCGAAACAGTACTGGTTTATTCTGTCCGCCCGTCTGGCTTTTGTCATAATCTTCC
AGAACCTCGTGATGTTCCTGAGCGTCCTCGTGGACTGGATGATTCCAGACATCCCCACGGACATCAGCGACCAGATCAAGAAAGAGAAGA
GCTTATTAGTGGATTTCTTCCTGAAAGAGGAGCATGAGAAGCTCAAGCTGATGGATGAGCCGGCTCTGAGGAGCCCAGGAGGTGGGGATC
GAAGCAGGAGCCGGGCAGCCAGCTCAGCACCTTCAGGCCAAAGCCAGCTGGGCAGCATGATGTCGTCAGGCTCTCAGCACACCAATGTGT
GAGCAGTTCAGCCTGCAGCAGAGGAGGGCACGGCAGCAGAGACACGCACATGCACGTAAGCATGTTCCTACACCCACATGGCGTGCTGTC
TGTCTGCAGGGGCCTGGCTTGATGGGGTCTTGAAGAGGGGGCAGTGTGTAAAAAGAAAGAGCCTGACAGAATGAGTGTAGGAAGGAAGAG
AAATGATGCTACATCTCAGAAACTTCAAGCTTAAGTTTCTTTTAGGTCCCCTTTTAAGCTGCATCCTTTTGAGGGATTGGAACCCCACTG
GGGTCTCTCCACCCCAGAGTCTCAGGCACCGCGAGCATTCCCATGTACCCTGGGGCACCCTCTTGTACTTCACCATCATTTCTGACTTTG
ACCAGCTGTAAGAGAAATGCAGTCAGGAGCACAGCATCCCCTACTTACTATCACTACAAGAAAACTGAGTCACTTGCAGTGGGGCTGCCA
CAGTCTCAGCAGATGCAAATTAAGTTACAAGGCTGAATGGTGCAGCCGCTGGACCTGATAGTAAGGTGCAAAGGTCCAAACCTGGGCTTG
TCTCCACTTCACGTCACAAAAACGTTTGGAGCTAAATGCAGATAACCATCATTTTATGAAAGTTCAGATTTAAAATAATAAAATAAATGG

>87470_87470_6_STK24-ANO2_STK24_chr13_99171496_ENST00000397517_ANO2_chr12_5756967_ENST00000546188_length(amino acids)=577AA_BP=94
MSAMAHSPVQSGLPGMQNLKADPEELFTKLEKIGKGSFGEVFKGIDNRTQKVVAIKIIDLEEAEDEIEDIQQEITVLSQCDSPYVTKYYG
SYLKDDEDKLTWKDRFPGYLMNFASILFMIALTFSIVFGVIVYRITTAAALSLNKATRSNVRVTVTATAVIINLVVILILDEIYGAVAKW
LTKIEVPKTEQTFEERLILKAFLLKFVNAYSPIFYVAFFKGRFVGRPGSYVYVFDGYRMEECAPGGCLMELCIQLSIIMLGKQLIQNNIF
EIGVPKLKKLFRKLKDETEAGETDSAHSKHPEQWDLDYSLEPYTGLTPEYMEMIIQFGFVTLFVASFPLAPVFALLNNVIEVRLDAKKFV
TELRRPDAVRTKDIGIWFDILSGIGKFSVISNAFVIAITSDFIPRLVYQYSYSHNGTLHGFVNHTLSFFNVSQLKEGTQPENSQFDQEVQ
FCRFKDYREPPWAPNPYEFSKQYWFILSARLAFVIIFQNLVMFLSVLVDWMIPDIPTDISDQIKKEKSLLVDFFLKEEHEKLKLMDEPAL

--------------------------------------------------------------
>87470_87470_7_STK24-ANO2_STK24_chr13_99171496_ENST00000539966_ANO2_chr12_5756967_ENST00000327087_length(transcript)=2455nt_BP=355nt
GCGCGGCCCGCGGGCCTCGCCGCCCCGCGCGGATCGTCGCGGCCCGGCCGTCCCGTCCCAGGAAGTGGCCGTCCTGAGCGCCATGGCTCA
CTCCCCGGTGCAGTCGGGCCTGCCCGGCATGCAGAACCTAAAGGCAGACCCAGAAGAGCTTTTTACAAAACTAGAGAAAATTGGGAAGGG
CTCCTTTGGAGAGGTGTTCAAAGGCATTGACAATCGGACTCAGAAAGTGGTTGCCATAAAGATCATTGATCTGGAAGAAGCTGAAGATGA
GATAGAGGACATTCAACAAGAAATCACAGTGCTGAGTCAGTGTGACAGTCCATATGTAACCAAATATTATGGATCCTATCTGAAGGATGA
TGAAGATAAACTGACCTGGAAGGATCGTTTCCCAGGTTACCTGATGAACTTTGCCTCCATCTTATTCATGATTGCCCTGACATTCTCAAT
CGTCTTTGGGGTGATAGTGTATCGAATAACAACTGCAGCCGCTCTGTCTCTCAATAAGGCTACACGCTCCAATGTCCGGGTGACAGTGAC
AGCAACAGCAGTCATCATCAACCTCGTGGTCATCCTCATCCTGGACGAGATCTACGGCGCTGTGGCCAAGTGGCTCACCAAAATTGAGGT
TCCGAAAACAGAACAGACTTTTGAAGAGCGCCTGATCCTCAAAGCTTTCTTGCTCAAGTTTGTCAATGCCTACTCCCCCATCTTCTATGT
GGCCTTTTTCAAAGGGAGGTTTGTGGGCAGGCCTGGAAGCTACGTCTATGTATTCGATGGTTACCGCATGGAAGAGTGTGCTCCAGGGGG
CTGTCTCATGGAGCTCTGCATTCAGCTCAGCATCATCATGTTGGGGAAGCAGTTGATCCAGAACAACATCTTTGAGATTGGAGTCCCGAA
GCTAAAGAAACTATTTCGAAAGCTGAAAGATGAGACCGAAGCTGGAGAAACTGACTCTGCCCATTCGAAACATCCAGAGCAGTGGGACCT
AGACTACAGCTTGGAACCATACACAGGACTGACTCCGGAGTACATGGAAATGATCATCCAGTTTGGTTTTGTCACCCTCTTCGTGGCCTC
CTTTCCCCTGGCACCTGTGTTTGCCCTCCTCAACAACGTCATTGAAGTGCGGCTCGATGCAAAGAAGTTTGTTACAGAGCTGAGACGGCC
GGATGCTGTAAGAACCAAAGATATCGGAATCTGGTTTGACATTCTCTCTGGAATTGGCAAGTTCTCTGTTATCAGCAACGCTTTTGTCAT
TGCGATCACCTCCGACTTTATCCCCCGCCTGGTGTACCAGTACTCCTACAGTCACAATGGGACTCTGCACGGCTTTGTCAACCACACCCT
CTCCTTTTTCAACGTCAGCCAGCTGAAGGAGGGGACGCAGCCAGAAAACTCACAGTTTGACCAGGAGGTTCAGTTCTGCAGGTTTAAGGA
TTACCGAGAGCCGCCATGGGCCCCGAACCCTTATGAGTTTTCGAAACAGTACTGGTTTATTCTGTCCGCCCGTCTGGCTTTTGTCATAAT
CTTCCAGAACCTCGTGATGTTCCTGAGCGTCCTCGTGGACTGGATGATTCCAGACATCCCCACGGACATCAGCGACCAGATCAAGAAAGA
GAAGAGCTTATTAGTGGATTTCTTCCTGAAAGAGGAGCATGAGAAGCTCAAGCTGATGGATGAGCCGGCTCTGAGGAGCCCAGGAGGTGG
GGATCGAAGCAGGAGCCGGGCAGCCAGCTCAGCACCTTCAGGCCAAAGCCAGCTGGGCAGCATGATGTCGTCAGGCTCTCAGCACACCAA
TGTGTGAGCAGTTCAGCCTGCAGCAGAGGAGGGCACGGCAGCAGAGACACGCACATGCACGTAAGCATGTTCCTACACCCACATGGCGTG
CTGTCTGTCTGCAGGGGCCTGGCTTGATGGGGTCTTGAAGAGGGGGCAGTGTGTAAAAAGAAAGAGCCTGACAGAATGAGTGTAGGAAGG
AAGAGAAATGATGCTACATCTCAGAAACTTCAAGCTTAAGTTTCTTTTAGGTCCCCTTTTAAGCTGCATCCTTTTGAGGGATTGGAACCC
CACTGGGGTCTCTCCACCCCAGAGTCTCAGGCACCGCGAGCATTCCCATGTACCCTGGGGCACCCTCTTGTACTTCACCATCATTTCTGA
CTTTGACCAGCTGTAAGAGAAATGCAGTCAGGAGCACAGCATCCCCTACTTACTATCACTACAAGAAAACTGAGTCACTTGCAGTGGGGC
TGCCACAGTCTCAGCAGATGCAAATTAAGTTACAAGGCTGAATGGTGCAGCCGCTGGACCTGATAGTAAGGTGCAAAGGTCCAAACCTGG
GCTTGTCTCCACTTCACGTCACAAAAACGTTTGGAGCTAAATGCAGATAACCATCATTTTATGAAAGTTCAGATTTAAAATAATAAAATA

>87470_87470_7_STK24-ANO2_STK24_chr13_99171496_ENST00000539966_ANO2_chr12_5756967_ENST00000327087_length(amino acids)=577AA_BP=94
MSAMAHSPVQSGLPGMQNLKADPEELFTKLEKIGKGSFGEVFKGIDNRTQKVVAIKIIDLEEAEDEIEDIQQEITVLSQCDSPYVTKYYG
SYLKDDEDKLTWKDRFPGYLMNFASILFMIALTFSIVFGVIVYRITTAAALSLNKATRSNVRVTVTATAVIINLVVILILDEIYGAVAKW
LTKIEVPKTEQTFEERLILKAFLLKFVNAYSPIFYVAFFKGRFVGRPGSYVYVFDGYRMEECAPGGCLMELCIQLSIIMLGKQLIQNNIF
EIGVPKLKKLFRKLKDETEAGETDSAHSKHPEQWDLDYSLEPYTGLTPEYMEMIIQFGFVTLFVASFPLAPVFALLNNVIEVRLDAKKFV
TELRRPDAVRTKDIGIWFDILSGIGKFSVISNAFVIAITSDFIPRLVYQYSYSHNGTLHGFVNHTLSFFNVSQLKEGTQPENSQFDQEVQ
FCRFKDYREPPWAPNPYEFSKQYWFILSARLAFVIIFQNLVMFLSVLVDWMIPDIPTDISDQIKKEKSLLVDFFLKEEHEKLKLMDEPAL

--------------------------------------------------------------
>87470_87470_8_STK24-ANO2_STK24_chr13_99171496_ENST00000539966_ANO2_chr12_5756967_ENST00000356134_length(transcript)=2452nt_BP=355nt
GCGCGGCCCGCGGGCCTCGCCGCCCCGCGCGGATCGTCGCGGCCCGGCCGTCCCGTCCCAGGAAGTGGCCGTCCTGAGCGCCATGGCTCA
CTCCCCGGTGCAGTCGGGCCTGCCCGGCATGCAGAACCTAAAGGCAGACCCAGAAGAGCTTTTTACAAAACTAGAGAAAATTGGGAAGGG
CTCCTTTGGAGAGGTGTTCAAAGGCATTGACAATCGGACTCAGAAAGTGGTTGCCATAAAGATCATTGATCTGGAAGAAGCTGAAGATGA
GATAGAGGACATTCAACAAGAAATCACAGTGCTGAGTCAGTGTGACAGTCCATATGTAACCAAATATTATGGATCCTATCTGAAGGATGA
TGAAGATAAACTGACCTGGAAGGATCGTTTCCCAGGTTACCTGATGAACTTTGCCTCCATCTTATTCATGATTGCCCTGACATTCTCAAT
CGTCTTTGGGGTGATAGTGTATCGAATAACAACTGCAGCCGCTCTGTCTCTCAATAAGGCTACACGCTCCAATGTCCGGGTGACAGTGAC
AGCAACAGCAGTCATCATCAACCTCGTGGTCATCCTCATCCTGGACGAGATCTACGGCGCTGTGGCCAAGTGGCTCACCAAAATTGAGGT
TCCGAAAACAGAACAGACTTTTGAAGAGCGCCTGATCCTCAAAGCTTTCTTGCTCAAGTTTGTCAATGCCTACTCCCCCATCTTCTATGT
GGCCTTTTTCAAAGGGAGGTTTGTGGGCAGGCCTGGAAGCTACGTCTATGTATTCGATGGTTACCGCATGGAAGAGTGTGCTCCAGGGGG
CTGTCTCATGGAGCTCTGCATTCAGCTCAGCATCATCATGTTGGGGAAGCAGTTGATCCAGAACAACATCTTTGAGATTGGAGTCCCGAA
GCTAAAGAAACTATTTCGAAAGCTGAAAGATGAGACCGAAGCTGGAGAAACTGACTCTGCCCATTCGAAACATCCAGAGCAGTGGGACCT
AGACTACAGCTTGGAACCATACACAGGACTGACTCCGGAGTACATGGAAATGATCATCCAGTTTGGTTTTGTCACCCTCTTCGTGGCCTC
CTTTCCCCTGGCACCTGTGTTTGCCCTCCTCAACAACGTCATTGAAGTGCGGCTCGATGCAAAGAAGTTTGTTACAGAGCTGAGACGGCC
GGATGCTGTAAGAACCAAAGATATCGGAATCTGGTTTGACATTCTCTCTGGAATTGGCAAGTTCTCTGTTATCAGCAACGCTTTTGTCAT
TGCGATCACCTCCGACTTTATCCCCCGCCTGGTGTACCAGTACTCCTACAGTCACAATGGGACTCTGCACGGCTTTGTCAACCACACCCT
CTCCTTTTTCAACGTCAGCCAGCTGAAGGAGGGGACGCAGCCAGAAAACTCACAGTTTGACCAGGAGGTTCAGTTCTGCAGGTTTAAGGA
TTACCGAGAGCCGCCATGGGCCCCGAACCCTTATGAGTTTTCGAAACAGTACTGGTTTATTCTGTCCGCCCGTCTGGCTTTTGTCATAAT
CTTCCAGAACCTCGTGATGTTCCTGAGCGTCCTCGTGGACTGGATGATTCCAGACATCCCCACGGACATCAGCGACCAGATCAAGAAAGA
GAAGAGCTTATTAGTGGATTTCTTCCTGAAAGAGGAGCATGAGAAGCTCAAGCTGATGGATGAGCCGGCTCTGAGGAGCCCAGGAGGTGG
GGATCGAAGCAGGAGCCGGGCAGCCAGCTCAGCACCTTCAGGCCAAAGCCAGCTGGGCAGCATGATGTCGTCAGGCTCTCAGCACACCAA
TGTGTGAGCAGTTCAGCCTGCAGCAGAGGAGGGCACGGCAGCAGAGACACGCACATGCACGTAAGCATGTTCCTACACCCACATGGCGTG
CTGTCTGTCTGCAGGGGCCTGGCTTGATGGGGTCTTGAAGAGGGGGCAGTGTGTAAAAAGAAAGAGCCTGACAGAATGAGTGTAGGAAGG
AAGAGAAATGATGCTACATCTCAGAAACTTCAAGCTTAAGTTTCTTTTAGGTCCCCTTTTAAGCTGCATCCTTTTGAGGGATTGGAACCC
CACTGGGGTCTCTCCACCCCAGAGTCTCAGGCACCGCGAGCATTCCCATGTACCCTGGGGCACCCTCTTGTACTTCACCATCATTTCTGA
CTTTGACCAGCTGTAAGAGAAATGCAGTCAGGAGCACAGCATCCCCTACTTACTATCACTACAAGAAAACTGAGTCACTTGCAGTGGGGC
TGCCACAGTCTCAGCAGATGCAAATTAAGTTACAAGGCTGAATGGTGCAGCCGCTGGACCTGATAGTAAGGTGCAAAGGTCCAAACCTGG
GCTTGTCTCCACTTCACGTCACAAAAACGTTTGGAGCTAAATGCAGATAACCATCATTTTATGAAAGTTCAGATTTAAAATAATAAAATA

>87470_87470_8_STK24-ANO2_STK24_chr13_99171496_ENST00000539966_ANO2_chr12_5756967_ENST00000356134_length(amino acids)=577AA_BP=94
MSAMAHSPVQSGLPGMQNLKADPEELFTKLEKIGKGSFGEVFKGIDNRTQKVVAIKIIDLEEAEDEIEDIQQEITVLSQCDSPYVTKYYG
SYLKDDEDKLTWKDRFPGYLMNFASILFMIALTFSIVFGVIVYRITTAAALSLNKATRSNVRVTVTATAVIINLVVILILDEIYGAVAKW
LTKIEVPKTEQTFEERLILKAFLLKFVNAYSPIFYVAFFKGRFVGRPGSYVYVFDGYRMEECAPGGCLMELCIQLSIIMLGKQLIQNNIF
EIGVPKLKKLFRKLKDETEAGETDSAHSKHPEQWDLDYSLEPYTGLTPEYMEMIIQFGFVTLFVASFPLAPVFALLNNVIEVRLDAKKFV
TELRRPDAVRTKDIGIWFDILSGIGKFSVISNAFVIAITSDFIPRLVYQYSYSHNGTLHGFVNHTLSFFNVSQLKEGTQPENSQFDQEVQ
FCRFKDYREPPWAPNPYEFSKQYWFILSARLAFVIIFQNLVMFLSVLVDWMIPDIPTDISDQIKKEKSLLVDFFLKEEHEKLKLMDEPAL

--------------------------------------------------------------
>87470_87470_9_STK24-ANO2_STK24_chr13_99171496_ENST00000539966_ANO2_chr12_5756967_ENST00000546188_length(transcript)=2452nt_BP=355nt
GCGCGGCCCGCGGGCCTCGCCGCCCCGCGCGGATCGTCGCGGCCCGGCCGTCCCGTCCCAGGAAGTGGCCGTCCTGAGCGCCATGGCTCA
CTCCCCGGTGCAGTCGGGCCTGCCCGGCATGCAGAACCTAAAGGCAGACCCAGAAGAGCTTTTTACAAAACTAGAGAAAATTGGGAAGGG
CTCCTTTGGAGAGGTGTTCAAAGGCATTGACAATCGGACTCAGAAAGTGGTTGCCATAAAGATCATTGATCTGGAAGAAGCTGAAGATGA
GATAGAGGACATTCAACAAGAAATCACAGTGCTGAGTCAGTGTGACAGTCCATATGTAACCAAATATTATGGATCCTATCTGAAGGATGA
TGAAGATAAACTGACCTGGAAGGATCGTTTCCCAGGTTACCTGATGAACTTTGCCTCCATCTTATTCATGATTGCCCTGACATTCTCAAT
CGTCTTTGGGGTGATAGTGTATCGAATAACAACTGCAGCCGCTCTGTCTCTCAATAAGGCTACACGCTCCAATGTCCGGGTGACAGTGAC
AGCAACAGCAGTCATCATCAACCTCGTGGTCATCCTCATCCTGGACGAGATCTACGGCGCTGTGGCCAAGTGGCTCACCAAAATTGAGGT
TCCGAAAACAGAACAGACTTTTGAAGAGCGCCTGATCCTCAAAGCTTTCTTGCTCAAGTTTGTCAATGCCTACTCCCCCATCTTCTATGT
GGCCTTTTTCAAAGGGAGGTTTGTGGGCAGGCCTGGAAGCTACGTCTATGTATTCGATGGTTACCGCATGGAAGAGTGTGCTCCAGGGGG
CTGTCTCATGGAGCTCTGCATTCAGCTCAGCATCATCATGTTGGGGAAGCAGTTGATCCAGAACAACATCTTTGAGATTGGAGTCCCGAA
GCTAAAGAAACTATTTCGAAAGCTGAAAGATGAGACCGAAGCTGGAGAAACTGACTCTGCCCATTCGAAACATCCAGAGCAGTGGGACCT
AGACTACAGCTTGGAACCATACACAGGACTGACTCCGGAGTACATGGAAATGATCATCCAGTTTGGTTTTGTCACCCTCTTCGTGGCCTC
CTTTCCCCTGGCACCTGTGTTTGCCCTCCTCAACAACGTCATTGAAGTGCGGCTCGATGCAAAGAAGTTTGTTACAGAGCTGAGACGGCC
GGATGCTGTAAGAACCAAAGATATCGGAATCTGGTTTGACATTCTCTCTGGAATTGGCAAGTTCTCTGTTATCAGCAACGCTTTTGTCAT
TGCGATCACCTCCGACTTTATCCCCCGCCTGGTGTACCAGTACTCCTACAGTCACAATGGGACTCTGCACGGCTTTGTCAACCACACCCT
CTCCTTTTTCAACGTCAGCCAGCTGAAGGAGGGGACGCAGCCAGAAAACTCACAGTTTGACCAGGAGGTTCAGTTCTGCAGGTTTAAGGA
TTACCGAGAGCCGCCATGGGCCCCGAACCCTTATGAGTTTTCGAAACAGTACTGGTTTATTCTGTCCGCCCGTCTGGCTTTTGTCATAAT
CTTCCAGAACCTCGTGATGTTCCTGAGCGTCCTCGTGGACTGGATGATTCCAGACATCCCCACGGACATCAGCGACCAGATCAAGAAAGA
GAAGAGCTTATTAGTGGATTTCTTCCTGAAAGAGGAGCATGAGAAGCTCAAGCTGATGGATGAGCCGGCTCTGAGGAGCCCAGGAGGTGG
GGATCGAAGCAGGAGCCGGGCAGCCAGCTCAGCACCTTCAGGCCAAAGCCAGCTGGGCAGCATGATGTCGTCAGGCTCTCAGCACACCAA
TGTGTGAGCAGTTCAGCCTGCAGCAGAGGAGGGCACGGCAGCAGAGACACGCACATGCACGTAAGCATGTTCCTACACCCACATGGCGTG
CTGTCTGTCTGCAGGGGCCTGGCTTGATGGGGTCTTGAAGAGGGGGCAGTGTGTAAAAAGAAAGAGCCTGACAGAATGAGTGTAGGAAGG
AAGAGAAATGATGCTACATCTCAGAAACTTCAAGCTTAAGTTTCTTTTAGGTCCCCTTTTAAGCTGCATCCTTTTGAGGGATTGGAACCC
CACTGGGGTCTCTCCACCCCAGAGTCTCAGGCACCGCGAGCATTCCCATGTACCCTGGGGCACCCTCTTGTACTTCACCATCATTTCTGA
CTTTGACCAGCTGTAAGAGAAATGCAGTCAGGAGCACAGCATCCCCTACTTACTATCACTACAAGAAAACTGAGTCACTTGCAGTGGGGC
TGCCACAGTCTCAGCAGATGCAAATTAAGTTACAAGGCTGAATGGTGCAGCCGCTGGACCTGATAGTAAGGTGCAAAGGTCCAAACCTGG
GCTTGTCTCCACTTCACGTCACAAAAACGTTTGGAGCTAAATGCAGATAACCATCATTTTATGAAAGTTCAGATTTAAAATAATAAAATA

>87470_87470_9_STK24-ANO2_STK24_chr13_99171496_ENST00000539966_ANO2_chr12_5756967_ENST00000546188_length(amino acids)=577AA_BP=94
MSAMAHSPVQSGLPGMQNLKADPEELFTKLEKIGKGSFGEVFKGIDNRTQKVVAIKIIDLEEAEDEIEDIQQEITVLSQCDSPYVTKYYG
SYLKDDEDKLTWKDRFPGYLMNFASILFMIALTFSIVFGVIVYRITTAAALSLNKATRSNVRVTVTATAVIINLVVILILDEIYGAVAKW
LTKIEVPKTEQTFEERLILKAFLLKFVNAYSPIFYVAFFKGRFVGRPGSYVYVFDGYRMEECAPGGCLMELCIQLSIIMLGKQLIQNNIF
EIGVPKLKKLFRKLKDETEAGETDSAHSKHPEQWDLDYSLEPYTGLTPEYMEMIIQFGFVTLFVASFPLAPVFALLNNVIEVRLDAKKFV
TELRRPDAVRTKDIGIWFDILSGIGKFSVISNAFVIAITSDFIPRLVYQYSYSHNGTLHGFVNHTLSFFNVSQLKEGTQPENSQFDQEVQ
FCRFKDYREPPWAPNPYEFSKQYWFILSARLAFVIIFQNLVMFLSVLVDWMIPDIPTDISDQIKKEKSLLVDFFLKEEHEKLKLMDEPAL

--------------------------------------------------------------

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Fusion Gene PPI Analysis for STK24-ANO2


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for STK24-ANO2


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for STK24-ANO2


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource