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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:STK3-NIPAL2 (FusionGDB2 ID:87576)

Fusion Gene Summary for STK3-NIPAL2

check button Fusion gene summary
Fusion gene informationFusion gene name: STK3-NIPAL2
Fusion gene ID: 87576
HgeneTgene
Gene symbol

STK3

NIPAL2

Gene ID

8428

79815

Gene nameserine/threonine kinase 24NIPA like domain containing 2
SynonymsHEL-S-95|MST3|MST3B|STE20|STK3NPAL2
Cytomap

13q32.2

8q22.2

Type of geneprotein-codingprotein-coding
Descriptionserine/threonine-protein kinase 24STE20-like kinase 3STE20-like kinase MST3epididymis secretory protein Li 95mammalian STE20-like protein kinase 3serine/threonine kinase 24 (STE20 homolog, yeast)sterile 20-like kinase 3NIPA-like protein 2
Modification date2020031320200313
UniProtAcc.

Q9H841

Ensembl transtripts involved in fusion geneENST00000419617, ENST00000523601, 
ENST00000521768, 		ENST00000520545, 
ENST00000341166, ENST00000430223, 
Fusion gene scores* DoF score24 X 16 X 11=42248 X 7 X 8=448
# samples 3011
** MAII scorelog2(30/4224*10)=-3.81557542886257
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(11/448*10)=-2.02599520853294
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: STK3 [Title/Abstract] AND NIPAL2 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointSTK3(99538969)-NIPAL2(99266315), # samples:2
Anticipated loss of major functional domain due to fusion event.STK3-NIPAL2 seems lost the major protein functional domain in Hgene partner, which is a IUPHAR drug target due to the frame-shifted ORF.
STK3-NIPAL2 seems lost the major protein functional domain in Hgene partner, which is a kinase due to the frame-shifted ORF.
STK3-NIPAL2 seems lost the major protein functional domain in Tgene partner, which is a IUPHAR drug target due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneSTK3

GO:0006468

protein phosphorylation

19604147

HgeneSTK3

GO:0042542

response to hydrogen peroxide

22291017

HgeneSTK3

GO:0046777

protein autophosphorylation

17046825|17657516


check buttonFusion gene breakpoints across STK3 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across NIPAL2 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4ESCATCGA-IC-A6RESTK3chr8

99538969

-NIPAL2chr8

99266315

-
ChimerDB4OVTCGA-25-1632STK3chr8

99538969

-NIPAL2chr8

99224729

-
ChimerDB4STADTCGA-D7-6822-01ASTK3chr8

99837743

-NIPAL2chr8

99266315

-


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Fusion Gene ORF analysis for STK3-NIPAL2

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-5UTRENST00000419617ENST00000520545STK3chr8

99538969

-NIPAL2chr8

99224729

-
5CDS-5UTRENST00000523601ENST00000520545STK3chr8

99538969

-NIPAL2chr8

99224729

-
5CDS-intronENST00000419617ENST00000520545STK3chr8

99538969

-NIPAL2chr8

99266315

-
5CDS-intronENST00000419617ENST00000520545STK3chr8

99837743

-NIPAL2chr8

99266315

-
5CDS-intronENST00000523601ENST00000520545STK3chr8

99538969

-NIPAL2chr8

99266315

-
Frame-shiftENST00000523601ENST00000341166STK3chr8

99538969

-NIPAL2chr8

99266315

-
Frame-shiftENST00000523601ENST00000341166STK3chr8

99538969

-NIPAL2chr8

99224729

-
Frame-shiftENST00000523601ENST00000430223STK3chr8

99538969

-NIPAL2chr8

99266315

-
Frame-shiftENST00000523601ENST00000430223STK3chr8

99538969

-NIPAL2chr8

99224729

-
In-frameENST00000419617ENST00000341166STK3chr8

99538969

-NIPAL2chr8

99266315

-
In-frameENST00000419617ENST00000341166STK3chr8

99538969

-NIPAL2chr8

99224729

-
In-frameENST00000419617ENST00000341166STK3chr8

99837743

-NIPAL2chr8

99266315

-
In-frameENST00000419617ENST00000430223STK3chr8

99538969

-NIPAL2chr8

99266315

-
In-frameENST00000419617ENST00000430223STK3chr8

99538969

-NIPAL2chr8

99224729

-
In-frameENST00000419617ENST00000430223STK3chr8

99837743

-NIPAL2chr8

99266315

-
intron-3CDSENST00000521768ENST00000341166STK3chr8

99538969

-NIPAL2chr8

99266315

-
intron-3CDSENST00000521768ENST00000341166STK3chr8

99538969

-NIPAL2chr8

99224729

-
intron-3CDSENST00000521768ENST00000341166STK3chr8

99837743

-NIPAL2chr8

99266315

-
intron-3CDSENST00000521768ENST00000430223STK3chr8

99538969

-NIPAL2chr8

99266315

-
intron-3CDSENST00000521768ENST00000430223STK3chr8

99538969

-NIPAL2chr8

99224729

-
intron-3CDSENST00000521768ENST00000430223STK3chr8

99837743

-NIPAL2chr8

99266315

-
intron-3CDSENST00000523601ENST00000341166STK3chr8

99837743

-NIPAL2chr8

99266315

-
intron-3CDSENST00000523601ENST00000430223STK3chr8

99837743

-NIPAL2chr8

99266315

-
intron-5UTRENST00000521768ENST00000520545STK3chr8

99538969

-NIPAL2chr8

99224729

-
intron-intronENST00000521768ENST00000520545STK3chr8

99538969

-NIPAL2chr8

99266315

-
intron-intronENST00000521768ENST00000520545STK3chr8

99837743

-NIPAL2chr8

99266315

-
intron-intronENST00000523601ENST00000520545STK3chr8

99837743

-NIPAL2chr8

99266315

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000419617STK3chr899538969-ENST00000430223NIPAL2chr899266315-56201458452474809
ENST00000419617STK3chr899538969-ENST00000341166NIPAL2chr899266315-56481458452429794
ENST00000419617STK3chr899538969-ENST00000430223NIPAL2chr899224729-51971458452051668
ENST00000419617STK3chr899538969-ENST00000341166NIPAL2chr899224729-52251458452006653
ENST00000419617STK3chr899837743-ENST00000430223NIPAL2chr899266315-43291671851183332
ENST00000419617STK3chr899837743-ENST00000341166NIPAL2chr899266315-43571671851138317

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000419617ENST00000430223STK3chr899538969-NIPAL2chr899266315-0.0004215370.9995784
ENST00000419617ENST00000341166STK3chr899538969-NIPAL2chr899266315-0.0004589210.99954116
ENST00000419617ENST00000430223STK3chr899538969-NIPAL2chr899224729-0.0004151750.99958485
ENST00000419617ENST00000341166STK3chr899538969-NIPAL2chr899224729-0.000406420.99959356
ENST00000419617ENST00000430223STK3chr899837743-NIPAL2chr899266315-0.0011955590.99880445
ENST00000419617ENST00000341166STK3chr899837743-NIPAL2chr899266315-0.0015394280.99846053

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Fusion Genomic Features for STK3-NIPAL2


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for STK3-NIPAL2


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr8:99538969/chr8:99266315)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
.NIPAL2

Q9H841

FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneSTK3chr8:99538969chr8:99224729ENST00000419617-1011287_328439492.0Coiled coilOntology_term=ECO:0000255
HgeneSTK3chr8:99538969chr8:99266315ENST00000419617-1011287_328439492.0Coiled coilOntology_term=ECO:0000255
HgeneSTK3chr8:99538969chr8:99224729ENST00000419617-1011308_314439492.0Compositional biasNote=Poly-Glu
HgeneSTK3chr8:99538969chr8:99224729ENST00000419617-1011370_375439492.0Compositional biasNote=Poly-Glu
HgeneSTK3chr8:99538969chr8:99266315ENST00000419617-1011308_314439492.0Compositional biasNote=Poly-Glu
HgeneSTK3chr8:99538969chr8:99266315ENST00000419617-1011370_375439492.0Compositional biasNote=Poly-Glu
HgeneSTK3chr8:99538969chr8:99224729ENST00000419617-101127_278439492.0DomainProtein kinase
HgeneSTK3chr8:99538969chr8:99266315ENST00000419617-101127_278439492.0DomainProtein kinase
HgeneSTK3chr8:99538969chr8:99224729ENST00000419617-101133_41439492.0Nucleotide bindingATP
HgeneSTK3chr8:99538969chr8:99266315ENST00000419617-101133_41439492.0Nucleotide bindingATP
TgeneNIPAL2chr8:99538969chr8:99224729ENST00000341166412209_229186369.0TransmembraneHelical
TgeneNIPAL2chr8:99538969chr8:99224729ENST00000341166412243_263186369.0TransmembraneHelical
TgeneNIPAL2chr8:99538969chr8:99224729ENST00000341166412278_298186369.0TransmembraneHelical
TgeneNIPAL2chr8:99538969chr8:99224729ENST00000341166412306_326186369.0TransmembraneHelical
TgeneNIPAL2chr8:99538969chr8:99266315ENST00000341166012110_13045369.0TransmembraneHelical
TgeneNIPAL2chr8:99538969chr8:99266315ENST00000341166012144_16445369.0TransmembraneHelical
TgeneNIPAL2chr8:99538969chr8:99266315ENST00000341166012177_19745369.0TransmembraneHelical
TgeneNIPAL2chr8:99538969chr8:99266315ENST00000341166012209_22945369.0TransmembraneHelical
TgeneNIPAL2chr8:99538969chr8:99266315ENST00000341166012243_26345369.0TransmembraneHelical
TgeneNIPAL2chr8:99538969chr8:99266315ENST00000341166012278_29845369.0TransmembraneHelical
TgeneNIPAL2chr8:99538969chr8:99266315ENST00000341166012306_32645369.0TransmembraneHelical
TgeneNIPAL2chr8:99538969chr8:99266315ENST0000034116601246_6645369.0TransmembraneHelical
TgeneNIPAL2chr8:99538969chr8:99266315ENST0000034116601288_10845369.0TransmembraneHelical
TgeneNIPAL2chr8:99837743chr8:99266315ENST00000341166012110_13045369.0TransmembraneHelical
TgeneNIPAL2chr8:99837743chr8:99266315ENST00000341166012144_16445369.0TransmembraneHelical
TgeneNIPAL2chr8:99837743chr8:99266315ENST00000341166012177_19745369.0TransmembraneHelical
TgeneNIPAL2chr8:99837743chr8:99266315ENST00000341166012209_22945369.0TransmembraneHelical
TgeneNIPAL2chr8:99837743chr8:99266315ENST00000341166012243_26345369.0TransmembraneHelical
TgeneNIPAL2chr8:99837743chr8:99266315ENST00000341166012278_29845369.0TransmembraneHelical
TgeneNIPAL2chr8:99837743chr8:99266315ENST00000341166012306_32645369.0TransmembraneHelical
TgeneNIPAL2chr8:99837743chr8:99266315ENST0000034116601246_6645369.0TransmembraneHelical
TgeneNIPAL2chr8:99837743chr8:99266315ENST0000034116601288_10845369.0TransmembraneHelical

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneSTK3chr8:99538969chr8:99224729ENST00000419617-1011442_475439492.0Coiled coilOntology_term=ECO:0000255
HgeneSTK3chr8:99538969chr8:99266315ENST00000419617-1011442_475439492.0Coiled coilOntology_term=ECO:0000255
HgeneSTK3chr8:99837743chr8:99266315ENST00000419617-111287_3288492.0Coiled coilOntology_term=ECO:0000255
HgeneSTK3chr8:99837743chr8:99266315ENST00000419617-111442_4758492.0Coiled coilOntology_term=ECO:0000255
HgeneSTK3chr8:99837743chr8:99266315ENST00000419617-111308_3148492.0Compositional biasNote=Poly-Glu
HgeneSTK3chr8:99837743chr8:99266315ENST00000419617-111370_3758492.0Compositional biasNote=Poly-Glu
HgeneSTK3chr8:99538969chr8:99224729ENST00000419617-1011437_484439492.0DomainSARAH
HgeneSTK3chr8:99538969chr8:99266315ENST00000419617-1011437_484439492.0DomainSARAH
HgeneSTK3chr8:99837743chr8:99266315ENST00000419617-11127_2788492.0DomainProtein kinase
HgeneSTK3chr8:99837743chr8:99266315ENST00000419617-111437_4848492.0DomainSARAH
HgeneSTK3chr8:99837743chr8:99266315ENST00000419617-11133_418492.0Nucleotide bindingATP
TgeneNIPAL2chr8:99538969chr8:99224729ENST00000341166412110_130186369.0TransmembraneHelical
TgeneNIPAL2chr8:99538969chr8:99224729ENST00000341166412144_164186369.0TransmembraneHelical
TgeneNIPAL2chr8:99538969chr8:99224729ENST00000341166412177_197186369.0TransmembraneHelical
TgeneNIPAL2chr8:99538969chr8:99224729ENST0000034116641246_66186369.0TransmembraneHelical
TgeneNIPAL2chr8:99538969chr8:99224729ENST0000034116641288_108186369.0TransmembraneHelical


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Fusion Gene Sequence for STK3-NIPAL2


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>87576_87576_1_STK3-NIPAL2_STK3_chr8_99538969_ENST00000419617_NIPAL2_chr8_99224729_ENST00000341166_length(transcript)=5225nt_BP=1458nt
CCGCGGAGTTACGGGAAAGTTGGTCCGAGTTCCCAGAGTTTCCCTCTGTGGTGCCCTAGGCTCGGCCGGCCGGTGCCCCGGCTCCTTTCC
TCCTTTCGGCCTTCGCCGTCCACCAGGTCCCTCTCTCTGTCCCCGGCCGCCATGGAGCAGCCGCCGGCGCCTAAGAGTAAACTAAAAAAG
CTGAGTGAAGACAGTTTGACTAAGCAGCCTGAAGAAGTTTTTGATGTATTAGAGAAGCTTGGAGAAGGGTCTTATGGAAGTGTATTTAAA
GCAATACACAAGGAATCCGGTCAAGTTGTCGCAATTAAACAAGTACCTGTTGAATCAGATCTTCAGGAAATAATCAAAGAAATTTCCATA
ATGCAGCAATGTGACAGCCCATATGTTGTAAAGTACTATGGCAGTTATTTTAAGAATACAGACCTCTGGATTGTTATGGAGTACTGTGGC
GCTGGCTCTGTCTCAGACATAATTAGATTACGAAACAAGACATTAATAGAAGATGAAATTGCAACCATTCTTAAATCTACATTGAAAGGA
CTAGAATATTTGCACTTTATGAGAAAAATACACAGAGATATAAAAGCTGGAAATATTCTCCTCAATACAGAAGGACATGCAAAATTGGCA
GATTTTGGAGTGGCTGGTCAGTTAACAGATACAATGGCAAAACGCAATACTGTAATAGGAACTCCATTTTGGATGGCTCCTGAGGTGATT
CAAGAAATAGGCTATAACTGTGTGGCCGACATCTGGTCCCTTGGCATTACTTCTATAGAAATGGCTGAAGGAAAACCTCCTTATGCTGAT
ATACATCCAATGAGGGCTATTTTTATGATTCCCACAAATCCACCACCAACATTCAGAAAGCCAGAACTTTGGTCCGATGATTTCACCGAT
TTTGTTAAAAAGTGTTTGGTGAAGAATCCTGAGCAGAGAGCTACTGCAACACAACTTTTACAGCATCCTTTTATCAAGAATGCCAAACCT
GTATCAATATTAAGAGACCTGATCACAGAAGCTATGGAGATCAAAGCTAAAAGACATGAGGAACAGCAACGAGAATTGGAAGAGGAAGAA
GAAAATTCGGATGAAGATGAGCTGGATTCCCACACCATGGTGAAGACTAGTGTGGAGAGTGTGGGCACCATGCGGGCCACAAGCACGATG
AGTGAAGGGGCCCAGACCATGATTGAACATAATAGCACGATGTTGGAATCCGACTTGGGGACCATGGTGATAAACAGTGAGGATGAGGAA
GAAGAAGATGGAACTATGAAAAGAAATGCAACCTCACCACAAGTACAAAGACCATCTTTCATGGACTACTTTGATAAGCAAGACTTCAAG
AATAAGAGTCACGAAAACTGTAATCAGAACATGCATGAACCCTTCCCTATGTCCAAAAACGTTTTTCCTGATAACTGGAAAGTTCCTCAA
GATGGAGACTTTGACTTTATTTTAGAAATATTAATTTTCTGCATTCTCCTGTATTTCTATAAAAGAAAAGGAATGAAGCATATGGTGATT
CTGCTAACCCTGGTGGCAATTCTAGCCTCATTGACTGTTATTTCAGTAAAGGCCGTCTCAGGCATGATCACTTTTTCTGTGATGGATAAA
ATGCAACTAACTTACCCCATTTTCTATATCATGTTTATCATCATGATAGCATCTTGTGTTTTCCAAGTCAAGTTCCTGAATCAAGCCACG
AAACTCTACAATACGACAACAGTGGTGCCAGTTAATCATATTTTCTTTACAATCAGTGCCATCATTGCAGGTATCATATTTTATCAGGAA
TTCCTTGGTGCTCCTTTTCTCACTGTATTTATATATCTTTTTGGGTGTTTTCTGTCATTCCTTGGTGTATTTTTGGTCACAAGAAATCGA
GAAAAGGAACATCTGCAACAGTCTTATATTGATTTTGGAAATATTCCTGACACAACCCCAGAGAGAAAGGCTTGGAGGGAAACAAATGTT
GGACAAAATACAACCAGATTCACATAGCTTATCCTATGGAACTTTGCCTGATGGAAGTGACTCAACAAAGAGCCAAAGTGGAGAGAAGAA
AGAGGTCTAAATGCTGAGAAGGATGGCTGTTGGCCTGTTATTCGATACCACCTTTTTAAAAAATTGCACATGTTCAATTTGTGTCAGCAG
CTCTTTTATAAGCTAACATGTGCTAGCATTCATTTCAGTCCTTTCCCCCACCTCAGCGTCTATGGACAATCGGGGACTTCCTAAGCTCTG
ACAGTCTAATATTTCCATGGAATGTGATTTGGAGTGTTCCCCACACCCTGGACCTCTCCCTAGTGATTATCTAGCCAGCTACACCTTACT
CAGAGCCCGGCTGCTCTAGCAGGAATGTTGCACAGAAACATACATTTGCGGTTTGGCCACAGGTCGCATAGGTGGCTTCTCCCACGGGTA
GTGTCAGTTGCTTCACTTTAAAAAGTCACTTCAGCCCCACAACCTCACTCCCAAAAGAAAGGTTTGAGAGCGCTCATTTTTTTTCTAAGA
CACCTTTTATAAGCCTCCCTATAAAAATCTCACCTTTCAAGTACTAAGTTAGAATTGCAAGTCATCTTTTCTGAAAACTAATGCTATCAA
AGTCCTCCTTTGAAAATTAAGGGTCTCTTTAAAATTAGAATTTATAAATGGCATTCAGTGATAGTGTACACCAAAATTAAAAGACCTTGA
CTGGTGGGCTTTTTACGTGTAAGGAAGAGGAAGTTTAAGAAGTAGGACTCTGCTTGTTTCAGTAGCCCATGTACTAAAATAGGAACAATG
CAGAGATTAGCACAGCCCCTGCACAAGGCTGACACATAAATTCATGAAGCGTTAGAGACAAAAAGTAGGACTAATGTTTGTTTATTTTTT
AATAAAAATCTAGAATGGTGATGTTTTCTTCAGCTGTATGATTCTATCATACTTGAAACTGAAGAAAAATTTAATATCCTATGTCTTTTT
TATAGATCTTATAATTTATCAAGTGGATTTATATGTCTTATTCTCCATATAAGTCTAAAAAATCACATTTAAATTCTTAGTGATAGTTTC
ACTACACATCATTTCTTCCCAAAGTCATTACCTCAAGCTTTGTAAATTCTTCTAGATAAAAGGAGAGTTGTGATTAGAGAACTGAATTTC
AGCCATTTAAACCTGTAGACATAGAAAACAACCCAGTGGTCAAACCTGAGCTTCAAGAGGAAGCCCAAGTCCTCCTGTTTCCTGAATGGC
TTTTCCACTCCAATTCATCACATATCTGCTAAGACACATTTGCAGGTAGAATCCATAATAATATCTGTTATTTATGATCTACCTAATATT
TAAAGGAGAAGAAAAGAAGTAGCCTTCGTTGCAGCCAACATCCAACAATAAGTCCCACCCTTAATGACATTTCAAAGCCTTCAGATCACT
TCTGACATGTCTGTCCAATATCATTCCAATCAATAGTCTTGCATTTAAATAGGTTGTTTAACTCGGTGGTATTGAGACTGTAACCTTAAT
GGCTCAGGTCTTTTAGCTTTGTTCTTTGTCATAATCTGCACTCCTGGCCAGACTGACCAAACCTGGCTGCAAAGGAAAGAGATTTGAATT
GATCACCAATGTATGAAAAATACAGAACCCATGTCTGGCTCCTAAACTCCTGGTAATAATTCCCGCCATCGTAGCAAGTGTCCCATGCAT
TCAGATAAAGCAGTCATAATTTATGGTGTATTTTACCGAATTGGTCCAGCATATTGGTCCTACAAGGCTCAGCCAAGAAATGTATCTGGT
GCCTTAAACTACAGATTTCTGGTGACTCTTAAAACTGGTTTACAAAGATTGAGAAAACAATTAGATTGAAGAGTTTTGCTTCAAGTAGAC
CTGCATTCATAGCTAGAGTGCATGAGATTTTCAGCACTGTAGAATTTCACACAGGCACAAGCATAACACCAGTACTTTAGCAGCCGCCAA
CAGTTGCATCTATTAAACGTTTTGAGAAATGACATTGACTTATGCACATTTAAGCAATCAACAATGTTTTAGAAGTCCAGGTAACATATA
AAATATATTCAGACCTAGTTTTACTTTCCATATTGTTGCTCCAAAGTAAGGTAAATAGGAGTTTTAGTTGTACTGGCCTGTAAGATTTTT
TAAATTACACAGTGCATGACAACAACTAAAGCCAACTCAGTCCTTCTCTTGGCATTGTGAGTTGAGGACCTTTAGCCAACTGTTAGCTCA
TCTGACTATCTGTCTAGACCAAGGGTCGGCAAAGTTTTCAGTAAAGACCCACAGAGTACATATTTTGGAGTTTGTGTTGTCTGTACCAAC
AGACAGACATGGTGTCTGTCCCAACTACCCAACTCTGCCATTGTAGCACTAAAGCAGCCATAGACAAGATGTAAACAGAAGAGCATGGCT
GTGTTCCAGTAAAACTTTATTTACAGGCCAGGCATGGTGGCTCATGCCTGTAATCCCAGCACTCTGGGAGGCTGAGGCTGACAGATCATC
TGAGGTTAGGAGTTTGGGACCAGCCTGGTCAACATAGTGAAACCCCATCTCTACTAAAAGTACAAAAATTAGCCAGGCATGACGGTGGGT
GCCTGGAGTCCCAGCTACCTGGGAGGCTGAGGCAGGAGAATCACTTGAACCCGGGAGGTGGAGGTTGCAGTGAGCCGAGATCATGCCATT
GCACTCCAGCCTGGGCGACAGAGTAAGACTGTCTCAAAAACAAACAAACAAACAAACAAACAAAAACAAGTGGCCAGTCTGTGAGCTATA
GTTCCCAACACCTGGTCTAGACTCTTCTGCCCTTGCTCTGCAGCTTCTTTCCTGTTGATTGGGCATTCAGGGAAGGAGTTTAAAAAGTGA
CACTCATGGCTCATGACAAATGAGATACTTTGGGAGTGTGGAAACATGGCTTGATATTTGCCTTCAGATATTTTTGCTTATATAAGTTCT
AAATGGAAGTGATAAGTTCATTCTTAGGGTCCAAGTTGAAAGGCAGTGGTTCTTTTGTGAACACCACTAACTACATTCGAAAAGCCTCTC
CAATTCCACATTCCAAGTCTATAACAGCTTTGGAAATGAGTAACAATGACCTCTCATGTAGTAGATTAAAGCAGAGGCCTTTGCCATATG
ATTGTTTTTTGGCTTAAATGTTTGCTTGCCCTGTAACTGTAATACTTTGGTTACCAGAATCACTTGAAAACAAATACAATAAAAAAATTT

>87576_87576_1_STK3-NIPAL2_STK3_chr8_99538969_ENST00000419617_NIPAL2_chr8_99224729_ENST00000341166_length(amino acids)=653AA_BP=1
MWCPRLGRPVPRLLSSFRPSPSTRSLSLSPAAMEQPPAPKSKLKKLSEDSLTKQPEEVFDVLEKLGEGSYGSVFKAIHKESGQVVAIKQV
PVESDLQEIIKEISIMQQCDSPYVVKYYGSYFKNTDLWIVMEYCGAGSVSDIIRLRNKTLIEDEIATILKSTLKGLEYLHFMRKIHRDIK
AGNILLNTEGHAKLADFGVAGQLTDTMAKRNTVIGTPFWMAPEVIQEIGYNCVADIWSLGITSIEMAEGKPPYADIHPMRAIFMIPTNPP
PTFRKPELWSDDFTDFVKKCLVKNPEQRATATQLLQHPFIKNAKPVSILRDLITEAMEIKAKRHEEQQRELEEEEENSDEDELDSHTMVK
TSVESVGTMRATSTMSEGAQTMIEHNSTMLESDLGTMVINSEDEEEEDGTMKRNATSPQVQRPSFMDYFDKQDFKNKSHENCNQNMHEPF
PMSKNVFPDNWKVPQDGDFDFILEILIFCILLYFYKRKGMKHMVILLTLVAILASLTVISVKAVSGMITFSVMDKMQLTYPIFYIMFIIM
IASCVFQVKFLNQATKLYNTTTVVPVNHIFFTISAIIAGIIFYQEFLGAPFLTVFIYLFGCFLSFLGVFLVTRNREKEHLQQSYIDFGNI

--------------------------------------------------------------
>87576_87576_2_STK3-NIPAL2_STK3_chr8_99538969_ENST00000419617_NIPAL2_chr8_99224729_ENST00000430223_length(transcript)=5197nt_BP=1458nt
CCGCGGAGTTACGGGAAAGTTGGTCCGAGTTCCCAGAGTTTCCCTCTGTGGTGCCCTAGGCTCGGCCGGCCGGTGCCCCGGCTCCTTTCC
TCCTTTCGGCCTTCGCCGTCCACCAGGTCCCTCTCTCTGTCCCCGGCCGCCATGGAGCAGCCGCCGGCGCCTAAGAGTAAACTAAAAAAG
CTGAGTGAAGACAGTTTGACTAAGCAGCCTGAAGAAGTTTTTGATGTATTAGAGAAGCTTGGAGAAGGGTCTTATGGAAGTGTATTTAAA
GCAATACACAAGGAATCCGGTCAAGTTGTCGCAATTAAACAAGTACCTGTTGAATCAGATCTTCAGGAAATAATCAAAGAAATTTCCATA
ATGCAGCAATGTGACAGCCCATATGTTGTAAAGTACTATGGCAGTTATTTTAAGAATACAGACCTCTGGATTGTTATGGAGTACTGTGGC
GCTGGCTCTGTCTCAGACATAATTAGATTACGAAACAAGACATTAATAGAAGATGAAATTGCAACCATTCTTAAATCTACATTGAAAGGA
CTAGAATATTTGCACTTTATGAGAAAAATACACAGAGATATAAAAGCTGGAAATATTCTCCTCAATACAGAAGGACATGCAAAATTGGCA
GATTTTGGAGTGGCTGGTCAGTTAACAGATACAATGGCAAAACGCAATACTGTAATAGGAACTCCATTTTGGATGGCTCCTGAGGTGATT
CAAGAAATAGGCTATAACTGTGTGGCCGACATCTGGTCCCTTGGCATTACTTCTATAGAAATGGCTGAAGGAAAACCTCCTTATGCTGAT
ATACATCCAATGAGGGCTATTTTTATGATTCCCACAAATCCACCACCAACATTCAGAAAGCCAGAACTTTGGTCCGATGATTTCACCGAT
TTTGTTAAAAAGTGTTTGGTGAAGAATCCTGAGCAGAGAGCTACTGCAACACAACTTTTACAGCATCCTTTTATCAAGAATGCCAAACCT
GTATCAATATTAAGAGACCTGATCACAGAAGCTATGGAGATCAAAGCTAAAAGACATGAGGAACAGCAACGAGAATTGGAAGAGGAAGAA
GAAAATTCGGATGAAGATGAGCTGGATTCCCACACCATGGTGAAGACTAGTGTGGAGAGTGTGGGCACCATGCGGGCCACAAGCACGATG
AGTGAAGGGGCCCAGACCATGATTGAACATAATAGCACGATGTTGGAATCCGACTTGGGGACCATGGTGATAAACAGTGAGGATGAGGAA
GAAGAAGATGGAACTATGAAAAGAAATGCAACCTCACCACAAGTACAAAGACCATCTTTCATGGACTACTTTGATAAGCAAGACTTCAAG
AATAAGAGTCACGAAAACTGTAATCAGAACATGCATGAACCCTTCCCTATGTCCAAAAACGTTTTTCCTGATAACTGGAAAGTTCCTCAA
GATGGAGACTTTGACTTTATTTTAGAAATATTAATTTTCTGCATTCTCCTGTATTTCTATAAAAGAAAAGGAATGAAGCATATGGTGATT
CTGCTAACCCTGGTGGCAATTCTAGCCTCATTGACTGTTATTTCAGTAAAGGCCGTCTCAGGCATGATCACTTTTTCTGTGATGGATAAA
ATGCAACTAACTTACCCCATTTTCTATATCATGTTTATCATCATGATAGCATCTTGTGTTTTCCAAGTCAAGTTCCTGAATCAAGCCACG
AAACTCTACAATACGACAACAGTGGTGCCAGTTAATCATATTTTCTTTACAATCAGTGCCATCATTGCAGGTATCATATTTTATCAGGAA
TTCCTTGGTGCTCCTTTTCTCACTGTATTTATATATCTTTTTGGGTGTTTTCTGTCATTCCTTGGTGTATTTTTGGTCACAAGAAATCGA
GAAAAGGAACATCTGCAACAGTCTTATATTGATTTTGGAAATATTCCTGGGAAACAAATGTTGGACAAAATACAACCAGATTCACATAGC
TTATCCTATGGAACTTTGCCTGATGGAAGTGACTCAACAAAGAGCCAAAGTGGAGAGAAGAAAGAGGTCTAAATGCTGAGAAGGATGGCT
GTTGGCCTGTTATTCGATACCACCTTTTTAAAAAATTGCACATGTTCAATTTGTGTCAGCAGCTCTTTTATAAGCTAACATGTGCTAGCA
TTCATTTCAGTCCTTTCCCCCACCTCAGCGTCTATGGACAATCGGGGACTTCCTAAGCTCTGACAGTCTAATATTTCCATGGAATGTGAT
TTGGAGTGTTCCCCACACCCTGGACCTCTCCCTAGTGATTATCTAGCCAGCTACACCTTACTCAGAGCCCGGCTGCTCTAGCAGGAATGT
TGCACAGAAACATACATTTGCGGTTTGGCCACAGGTCGCATAGGTGGCTTCTCCCACGGGTAGTGTCAGTTGCTTCACTTTAAAAAGTCA
CTTCAGCCCCACAACCTCACTCCCAAAAGAAAGGTTTGAGAGCGCTCATTTTTTTTCTAAGACACCTTTTATAAGCCTCCCTATAAAAAT
CTCACCTTTCAAGTACTAAGTTAGAATTGCAAGTCATCTTTTCTGAAAACTAATGCTATCAAAGTCCTCCTTTGAAAATTAAGGGTCTCT
TTAAAATTAGAATTTATAAATGGCATTCAGTGATAGTGTACACCAAAATTAAAAGACCTTGACTGGTGGGCTTTTTACGTGTAAGGAAGA
GGAAGTTTAAGAAGTAGGACTCTGCTTGTTTCAGTAGCCCATGTACTAAAATAGGAACAATGCAGAGATTAGCACAGCCCCTGCACAAGG
CTGACACATAAATTCATGAAGCGTTAGAGACAAAAAGTAGGACTAATGTTTGTTTATTTTTTAATAAAAATCTAGAATGGTGATGTTTTC
TTCAGCTGTATGATTCTATCATACTTGAAACTGAAGAAAAATTTAATATCCTATGTCTTTTTTATAGATCTTATAATTTATCAAGTGGAT
TTATATGTCTTATTCTCCATATAAGTCTAAAAAATCACATTTAAATTCTTAGTGATAGTTTCACTACACATCATTTCTTCCCAAAGTCAT
TACCTCAAGCTTTGTAAATTCTTCTAGATAAAAGGAGAGTTGTGATTAGAGAACTGAATTTCAGCCATTTAAACCTGTAGACATAGAAAA
CAACCCAGTGGTCAAACCTGAGCTTCAAGAGGAAGCCCAAGTCCTCCTGTTTCCTGAATGGCTTTTCCACTCCAATTCATCACATATCTG
CTAAGACACATTTGCAGGTAGAATCCATAATAATATCTGTTATTTATGATCTACCTAATATTTAAAGGAGAAGAAAAGAAGTAGCCTTCG
TTGCAGCCAACATCCAACAATAAGTCCCACCCTTAATGACATTTCAAAGCCTTCAGATCACTTCTGACATGTCTGTCCAATATCATTCCA
ATCAATAGTCTTGCATTTAAATAGGTTGTTTAACTCGGTGGTATTGAGACTGTAACCTTAATGGCTCAGGTCTTTTAGCTTTGTTCTTTG
TCATAATCTGCACTCCTGGCCAGACTGACCAAACCTGGCTGCAAAGGAAAGAGATTTGAATTGATCACCAATGTATGAAAAATACAGAAC
CCATGTCTGGCTCCTAAACTCCTGGTAATAATTCCCGCCATCGTAGCAAGTGTCCCATGCATTCAGATAAAGCAGTCATAATTTATGGTG
TATTTTACCGAATTGGTCCAGCATATTGGTCCTACAAGGCTCAGCCAAGAAATGTATCTGGTGCCTTAAACTACAGATTTCTGGTGACTC
TTAAAACTGGTTTACAAAGATTGAGAAAACAATTAGATTGAAGAGTTTTGCTTCAAGTAGACCTGCATTCATAGCTAGAGTGCATGAGAT
TTTCAGCACTGTAGAATTTCACACAGGCACAAGCATAACACCAGTACTTTAGCAGCCGCCAACAGTTGCATCTATTAAACGTTTTGAGAA
ATGACATTGACTTATGCACATTTAAGCAATCAACAATGTTTTAGAAGTCCAGGTAACATATAAAATATATTCAGACCTAGTTTTACTTTC
CATATTGTTGCTCCAAAGTAAGGTAAATAGGAGTTTTAGTTGTACTGGCCTGTAAGATTTTTTAAATTACACAGTGCATGACAACAACTA
AAGCCAACTCAGTCCTTCTCTTGGCATTGTGAGTTGAGGACCTTTAGCCAACTGTTAGCTCATCTGACTATCTGTCTAGACCAAGGGTCG
GCAAAGTTTTCAGTAAAGACCCACAGAGTACATATTTTGGAGTTTGTGTTGTCTGTACCAACAGACAGACATGGTGTCTGTCCCAACTAC
CCAACTCTGCCATTGTAGCACTAAAGCAGCCATAGACAAGATGTAAACAGAAGAGCATGGCTGTGTTCCAGTAAAACTTTATTTACAGGC
CAGGCATGGTGGCTCATGCCTGTAATCCCAGCACTCTGGGAGGCTGAGGCTGACAGATCATCTGAGGTTAGGAGTTTGGGACCAGCCTGG
TCAACATAGTGAAACCCCATCTCTACTAAAAGTACAAAAATTAGCCAGGCATGACGGTGGGTGCCTGGAGTCCCAGCTACCTGGGAGGCT
GAGGCAGGAGAATCACTTGAACCCGGGAGGTGGAGGTTGCAGTGAGCCGAGATCATGCCATTGCACTCCAGCCTGGGCGACAGAGTAAGA
CTGTCTCAAAAACAAACAAACAAACAAACAAACAAAAACAAGTGGCCAGTCTGTGAGCTATAGTTCCCAACACCTGGTCTAGACTCTTCT
GCCCTTGCTCTGCAGCTTCTTTCCTGTTGATTGGGCATTCAGGGAAGGAGTTTAAAAAGTGACACTCATGGCTCATGACAAATGAGATAC
TTTGGGAGTGTGGAAACATGGCTTGATATTTGCCTTCAGATATTTTTGCTTATATAAGTTCTAAATGGAAGTGATAAGTTCATTCTTAGG
GTCCAAGTTGAAAGGCAGTGGTTCTTTTGTGAACACCACTAACTACATTCGAAAAGCCTCTCCAATTCCACATTCCAAGTCTATAACAGC
TTTGGAAATGAGTAACAATGACCTCTCATGTAGTAGATTAAAGCAGAGGCCTTTGCCATATGATTGTTTTTTGGCTTAAATGTTTGCTTG

>87576_87576_2_STK3-NIPAL2_STK3_chr8_99538969_ENST00000419617_NIPAL2_chr8_99224729_ENST00000430223_length(amino acids)=668AA_BP=1
MWCPRLGRPVPRLLSSFRPSPSTRSLSLSPAAMEQPPAPKSKLKKLSEDSLTKQPEEVFDVLEKLGEGSYGSVFKAIHKESGQVVAIKQV
PVESDLQEIIKEISIMQQCDSPYVVKYYGSYFKNTDLWIVMEYCGAGSVSDIIRLRNKTLIEDEIATILKSTLKGLEYLHFMRKIHRDIK
AGNILLNTEGHAKLADFGVAGQLTDTMAKRNTVIGTPFWMAPEVIQEIGYNCVADIWSLGITSIEMAEGKPPYADIHPMRAIFMIPTNPP
PTFRKPELWSDDFTDFVKKCLVKNPEQRATATQLLQHPFIKNAKPVSILRDLITEAMEIKAKRHEEQQRELEEEEENSDEDELDSHTMVK
TSVESVGTMRATSTMSEGAQTMIEHNSTMLESDLGTMVINSEDEEEEDGTMKRNATSPQVQRPSFMDYFDKQDFKNKSHENCNQNMHEPF
PMSKNVFPDNWKVPQDGDFDFILEILIFCILLYFYKRKGMKHMVILLTLVAILASLTVISVKAVSGMITFSVMDKMQLTYPIFYIMFIIM
IASCVFQVKFLNQATKLYNTTTVVPVNHIFFTISAIIAGIIFYQEFLGAPFLTVFIYLFGCFLSFLGVFLVTRNREKEHLQQSYIDFGNI

--------------------------------------------------------------
>87576_87576_3_STK3-NIPAL2_STK3_chr8_99538969_ENST00000419617_NIPAL2_chr8_99266315_ENST00000341166_length(transcript)=5648nt_BP=1458nt
CCGCGGAGTTACGGGAAAGTTGGTCCGAGTTCCCAGAGTTTCCCTCTGTGGTGCCCTAGGCTCGGCCGGCCGGTGCCCCGGCTCCTTTCC
TCCTTTCGGCCTTCGCCGTCCACCAGGTCCCTCTCTCTGTCCCCGGCCGCCATGGAGCAGCCGCCGGCGCCTAAGAGTAAACTAAAAAAG
CTGAGTGAAGACAGTTTGACTAAGCAGCCTGAAGAAGTTTTTGATGTATTAGAGAAGCTTGGAGAAGGGTCTTATGGAAGTGTATTTAAA
GCAATACACAAGGAATCCGGTCAAGTTGTCGCAATTAAACAAGTACCTGTTGAATCAGATCTTCAGGAAATAATCAAAGAAATTTCCATA
ATGCAGCAATGTGACAGCCCATATGTTGTAAAGTACTATGGCAGTTATTTTAAGAATACAGACCTCTGGATTGTTATGGAGTACTGTGGC
GCTGGCTCTGTCTCAGACATAATTAGATTACGAAACAAGACATTAATAGAAGATGAAATTGCAACCATTCTTAAATCTACATTGAAAGGA
CTAGAATATTTGCACTTTATGAGAAAAATACACAGAGATATAAAAGCTGGAAATATTCTCCTCAATACAGAAGGACATGCAAAATTGGCA
GATTTTGGAGTGGCTGGTCAGTTAACAGATACAATGGCAAAACGCAATACTGTAATAGGAACTCCATTTTGGATGGCTCCTGAGGTGATT
CAAGAAATAGGCTATAACTGTGTGGCCGACATCTGGTCCCTTGGCATTACTTCTATAGAAATGGCTGAAGGAAAACCTCCTTATGCTGAT
ATACATCCAATGAGGGCTATTTTTATGATTCCCACAAATCCACCACCAACATTCAGAAAGCCAGAACTTTGGTCCGATGATTTCACCGAT
TTTGTTAAAAAGTGTTTGGTGAAGAATCCTGAGCAGAGAGCTACTGCAACACAACTTTTACAGCATCCTTTTATCAAGAATGCCAAACCT
GTATCAATATTAAGAGACCTGATCACAGAAGCTATGGAGATCAAAGCTAAAAGACATGAGGAACAGCAACGAGAATTGGAAGAGGAAGAA
GAAAATTCGGATGAAGATGAGCTGGATTCCCACACCATGGTGAAGACTAGTGTGGAGAGTGTGGGCACCATGCGGGCCACAAGCACGATG
AGTGAAGGGGCCCAGACCATGATTGAACATAATAGCACGATGTTGGAATCCGACTTGGGGACCATGGTGATAAACAGTGAGGATGAGGAA
GAAGAAGATGGAACTATGAAAAGAAATGCAACCTCACCACAAGTACAAAGACCATCTTTCATGGACTACTTTGATAAGCAAGACTTCAAG
AATAAGAGTCACGAAAACTGTAATCAGAACATGCATGAACCCTTCCCTATGTCCAAAAACGTTTTTCCTGATAACTGGAAAGTTCCTCAA
GATGGAGACTTTGACTTTATTCACCTTTTTGGAGTTTTGCTGGCTATTTTAGGAAACTTGGTGATCAGTATTTCTCTAAATATTCAGAAA
TATTCTCACCTTCAGCTGGCACAACAAGAGCACCCAAGGCCATACTTCAAGAGTGTGCTGTGGTGGGGTGGTGTCCTGCTGATGGCCGTG
GGAGAGACGGGGAACTTTGCAGCCTATGGATTTGCTCCCATTACTCTGATCGCTCCGTTAGGCTGTGTGTCTGTTACAGGTAGTGCCATT
ATTTCTGTTACATTTCTGAAAGACAATTTGAGAGCCTCAGACTTACTCGGTACGACACTGGCATTTGCAGGAACATATTTACTGGTGAAC
TTTGCTCCAAATATAACTCAGGCAATCTCAGCAAGAACAGTACAGTATTACCTTGTCGGATGGCAGTTCCTGATCTATGTGATTTTAGAA
ATATTAATTTTCTGCATTCTCCTGTATTTCTATAAAAGAAAAGGAATGAAGCATATGGTGATTCTGCTAACCCTGGTGGCAATTCTAGCC
TCATTGACTGTTATTTCAGTAAAGGCCGTCTCAGGCATGATCACTTTTTCTGTGATGGATAAAATGCAACTAACTTACCCCATTTTCTAT
ATCATGTTTATCATCATGATAGCATCTTGTGTTTTCCAAGTCAAGTTCCTGAATCAAGCCACGAAACTCTACAATACGACAACAGTGGTG
CCAGTTAATCATATTTTCTTTACAATCAGTGCCATCATTGCAGGTATCATATTTTATCAGGAATTCCTTGGTGCTCCTTTTCTCACTGTA
TTTATATATCTTTTTGGGTGTTTTCTGTCATTCCTTGGTGTATTTTTGGTCACAAGAAATCGAGAAAAGGAACATCTGCAACAGTCTTAT
ATTGATTTTGGAAATATTCCTGACACAACCCCAGAGAGAAAGGCTTGGAGGGAAACAAATGTTGGACAAAATACAACCAGATTCACATAG
CTTATCCTATGGAACTTTGCCTGATGGAAGTGACTCAACAAAGAGCCAAAGTGGAGAGAAGAAAGAGGTCTAAATGCTGAGAAGGATGGC
TGTTGGCCTGTTATTCGATACCACCTTTTTAAAAAATTGCACATGTTCAATTTGTGTCAGCAGCTCTTTTATAAGCTAACATGTGCTAGC
ATTCATTTCAGTCCTTTCCCCCACCTCAGCGTCTATGGACAATCGGGGACTTCCTAAGCTCTGACAGTCTAATATTTCCATGGAATGTGA
TTTGGAGTGTTCCCCACACCCTGGACCTCTCCCTAGTGATTATCTAGCCAGCTACACCTTACTCAGAGCCCGGCTGCTCTAGCAGGAATG
TTGCACAGAAACATACATTTGCGGTTTGGCCACAGGTCGCATAGGTGGCTTCTCCCACGGGTAGTGTCAGTTGCTTCACTTTAAAAAGTC
ACTTCAGCCCCACAACCTCACTCCCAAAAGAAAGGTTTGAGAGCGCTCATTTTTTTTCTAAGACACCTTTTATAAGCCTCCCTATAAAAA
TCTCACCTTTCAAGTACTAAGTTAGAATTGCAAGTCATCTTTTCTGAAAACTAATGCTATCAAAGTCCTCCTTTGAAAATTAAGGGTCTC
TTTAAAATTAGAATTTATAAATGGCATTCAGTGATAGTGTACACCAAAATTAAAAGACCTTGACTGGTGGGCTTTTTACGTGTAAGGAAG
AGGAAGTTTAAGAAGTAGGACTCTGCTTGTTTCAGTAGCCCATGTACTAAAATAGGAACAATGCAGAGATTAGCACAGCCCCTGCACAAG
GCTGACACATAAATTCATGAAGCGTTAGAGACAAAAAGTAGGACTAATGTTTGTTTATTTTTTAATAAAAATCTAGAATGGTGATGTTTT
CTTCAGCTGTATGATTCTATCATACTTGAAACTGAAGAAAAATTTAATATCCTATGTCTTTTTTATAGATCTTATAATTTATCAAGTGGA
TTTATATGTCTTATTCTCCATATAAGTCTAAAAAATCACATTTAAATTCTTAGTGATAGTTTCACTACACATCATTTCTTCCCAAAGTCA
TTACCTCAAGCTTTGTAAATTCTTCTAGATAAAAGGAGAGTTGTGATTAGAGAACTGAATTTCAGCCATTTAAACCTGTAGACATAGAAA
ACAACCCAGTGGTCAAACCTGAGCTTCAAGAGGAAGCCCAAGTCCTCCTGTTTCCTGAATGGCTTTTCCACTCCAATTCATCACATATCT
GCTAAGACACATTTGCAGGTAGAATCCATAATAATATCTGTTATTTATGATCTACCTAATATTTAAAGGAGAAGAAAAGAAGTAGCCTTC
GTTGCAGCCAACATCCAACAATAAGTCCCACCCTTAATGACATTTCAAAGCCTTCAGATCACTTCTGACATGTCTGTCCAATATCATTCC
AATCAATAGTCTTGCATTTAAATAGGTTGTTTAACTCGGTGGTATTGAGACTGTAACCTTAATGGCTCAGGTCTTTTAGCTTTGTTCTTT
GTCATAATCTGCACTCCTGGCCAGACTGACCAAACCTGGCTGCAAAGGAAAGAGATTTGAATTGATCACCAATGTATGAAAAATACAGAA
CCCATGTCTGGCTCCTAAACTCCTGGTAATAATTCCCGCCATCGTAGCAAGTGTCCCATGCATTCAGATAAAGCAGTCATAATTTATGGT
GTATTTTACCGAATTGGTCCAGCATATTGGTCCTACAAGGCTCAGCCAAGAAATGTATCTGGTGCCTTAAACTACAGATTTCTGGTGACT
CTTAAAACTGGTTTACAAAGATTGAGAAAACAATTAGATTGAAGAGTTTTGCTTCAAGTAGACCTGCATTCATAGCTAGAGTGCATGAGA
TTTTCAGCACTGTAGAATTTCACACAGGCACAAGCATAACACCAGTACTTTAGCAGCCGCCAACAGTTGCATCTATTAAACGTTTTGAGA
AATGACATTGACTTATGCACATTTAAGCAATCAACAATGTTTTAGAAGTCCAGGTAACATATAAAATATATTCAGACCTAGTTTTACTTT
CCATATTGTTGCTCCAAAGTAAGGTAAATAGGAGTTTTAGTTGTACTGGCCTGTAAGATTTTTTAAATTACACAGTGCATGACAACAACT
AAAGCCAACTCAGTCCTTCTCTTGGCATTGTGAGTTGAGGACCTTTAGCCAACTGTTAGCTCATCTGACTATCTGTCTAGACCAAGGGTC
GGCAAAGTTTTCAGTAAAGACCCACAGAGTACATATTTTGGAGTTTGTGTTGTCTGTACCAACAGACAGACATGGTGTCTGTCCCAACTA
CCCAACTCTGCCATTGTAGCACTAAAGCAGCCATAGACAAGATGTAAACAGAAGAGCATGGCTGTGTTCCAGTAAAACTTTATTTACAGG
CCAGGCATGGTGGCTCATGCCTGTAATCCCAGCACTCTGGGAGGCTGAGGCTGACAGATCATCTGAGGTTAGGAGTTTGGGACCAGCCTG
GTCAACATAGTGAAACCCCATCTCTACTAAAAGTACAAAAATTAGCCAGGCATGACGGTGGGTGCCTGGAGTCCCAGCTACCTGGGAGGC
TGAGGCAGGAGAATCACTTGAACCCGGGAGGTGGAGGTTGCAGTGAGCCGAGATCATGCCATTGCACTCCAGCCTGGGCGACAGAGTAAG
ACTGTCTCAAAAACAAACAAACAAACAAACAAACAAAAACAAGTGGCCAGTCTGTGAGCTATAGTTCCCAACACCTGGTCTAGACTCTTC
TGCCCTTGCTCTGCAGCTTCTTTCCTGTTGATTGGGCATTCAGGGAAGGAGTTTAAAAAGTGACACTCATGGCTCATGACAAATGAGATA
CTTTGGGAGTGTGGAAACATGGCTTGATATTTGCCTTCAGATATTTTTGCTTATATAAGTTCTAAATGGAAGTGATAAGTTCATTCTTAG
GGTCCAAGTTGAAAGGCAGTGGTTCTTTTGTGAACACCACTAACTACATTCGAAAAGCCTCTCCAATTCCACATTCCAAGTCTATAACAG
CTTTGGAAATGAGTAACAATGACCTCTCATGTAGTAGATTAAAGCAGAGGCCTTTGCCATATGATTGTTTTTTGGCTTAAATGTTTGCTT

>87576_87576_3_STK3-NIPAL2_STK3_chr8_99538969_ENST00000419617_NIPAL2_chr8_99266315_ENST00000341166_length(amino acids)=794AA_BP=1
MWCPRLGRPVPRLLSSFRPSPSTRSLSLSPAAMEQPPAPKSKLKKLSEDSLTKQPEEVFDVLEKLGEGSYGSVFKAIHKESGQVVAIKQV
PVESDLQEIIKEISIMQQCDSPYVVKYYGSYFKNTDLWIVMEYCGAGSVSDIIRLRNKTLIEDEIATILKSTLKGLEYLHFMRKIHRDIK
AGNILLNTEGHAKLADFGVAGQLTDTMAKRNTVIGTPFWMAPEVIQEIGYNCVADIWSLGITSIEMAEGKPPYADIHPMRAIFMIPTNPP
PTFRKPELWSDDFTDFVKKCLVKNPEQRATATQLLQHPFIKNAKPVSILRDLITEAMEIKAKRHEEQQRELEEEEENSDEDELDSHTMVK
TSVESVGTMRATSTMSEGAQTMIEHNSTMLESDLGTMVINSEDEEEEDGTMKRNATSPQVQRPSFMDYFDKQDFKNKSHENCNQNMHEPF
PMSKNVFPDNWKVPQDGDFDFIHLFGVLLAILGNLVISISLNIQKYSHLQLAQQEHPRPYFKSVLWWGGVLLMAVGETGNFAAYGFAPIT
LIAPLGCVSVTGSAIISVTFLKDNLRASDLLGTTLAFAGTYLLVNFAPNITQAISARTVQYYLVGWQFLIYVILEILIFCILLYFYKRKG
MKHMVILLTLVAILASLTVISVKAVSGMITFSVMDKMQLTYPIFYIMFIIMIASCVFQVKFLNQATKLYNTTTVVPVNHIFFTISAIIAG

--------------------------------------------------------------
>87576_87576_4_STK3-NIPAL2_STK3_chr8_99538969_ENST00000419617_NIPAL2_chr8_99266315_ENST00000430223_length(transcript)=5620nt_BP=1458nt
CCGCGGAGTTACGGGAAAGTTGGTCCGAGTTCCCAGAGTTTCCCTCTGTGGTGCCCTAGGCTCGGCCGGCCGGTGCCCCGGCTCCTTTCC
TCCTTTCGGCCTTCGCCGTCCACCAGGTCCCTCTCTCTGTCCCCGGCCGCCATGGAGCAGCCGCCGGCGCCTAAGAGTAAACTAAAAAAG
CTGAGTGAAGACAGTTTGACTAAGCAGCCTGAAGAAGTTTTTGATGTATTAGAGAAGCTTGGAGAAGGGTCTTATGGAAGTGTATTTAAA
GCAATACACAAGGAATCCGGTCAAGTTGTCGCAATTAAACAAGTACCTGTTGAATCAGATCTTCAGGAAATAATCAAAGAAATTTCCATA
ATGCAGCAATGTGACAGCCCATATGTTGTAAAGTACTATGGCAGTTATTTTAAGAATACAGACCTCTGGATTGTTATGGAGTACTGTGGC
GCTGGCTCTGTCTCAGACATAATTAGATTACGAAACAAGACATTAATAGAAGATGAAATTGCAACCATTCTTAAATCTACATTGAAAGGA
CTAGAATATTTGCACTTTATGAGAAAAATACACAGAGATATAAAAGCTGGAAATATTCTCCTCAATACAGAAGGACATGCAAAATTGGCA
GATTTTGGAGTGGCTGGTCAGTTAACAGATACAATGGCAAAACGCAATACTGTAATAGGAACTCCATTTTGGATGGCTCCTGAGGTGATT
CAAGAAATAGGCTATAACTGTGTGGCCGACATCTGGTCCCTTGGCATTACTTCTATAGAAATGGCTGAAGGAAAACCTCCTTATGCTGAT
ATACATCCAATGAGGGCTATTTTTATGATTCCCACAAATCCACCACCAACATTCAGAAAGCCAGAACTTTGGTCCGATGATTTCACCGAT
TTTGTTAAAAAGTGTTTGGTGAAGAATCCTGAGCAGAGAGCTACTGCAACACAACTTTTACAGCATCCTTTTATCAAGAATGCCAAACCT
GTATCAATATTAAGAGACCTGATCACAGAAGCTATGGAGATCAAAGCTAAAAGACATGAGGAACAGCAACGAGAATTGGAAGAGGAAGAA
GAAAATTCGGATGAAGATGAGCTGGATTCCCACACCATGGTGAAGACTAGTGTGGAGAGTGTGGGCACCATGCGGGCCACAAGCACGATG
AGTGAAGGGGCCCAGACCATGATTGAACATAATAGCACGATGTTGGAATCCGACTTGGGGACCATGGTGATAAACAGTGAGGATGAGGAA
GAAGAAGATGGAACTATGAAAAGAAATGCAACCTCACCACAAGTACAAAGACCATCTTTCATGGACTACTTTGATAAGCAAGACTTCAAG
AATAAGAGTCACGAAAACTGTAATCAGAACATGCATGAACCCTTCCCTATGTCCAAAAACGTTTTTCCTGATAACTGGAAAGTTCCTCAA
GATGGAGACTTTGACTTTATTCACCTTTTTGGAGTTTTGCTGGCTATTTTAGGAAACTTGGTGATCAGTATTTCTCTAAATATTCAGAAA
TATTCTCACCTTCAGCTGGCACAACAAGAGCACCCAAGGCCATACTTCAAGAGTGTGCTGTGGTGGGGTGGTGTCCTGCTGATGGCCGTG
GGAGAGACGGGGAACTTTGCAGCCTATGGATTTGCTCCCATTACTCTGATCGCTCCGTTAGGCTGTGTGTCTGTTACAGGTAGTGCCATT
ATTTCTGTTACATTTCTGAAAGACAATTTGAGAGCCTCAGACTTACTCGGTACGACACTGGCATTTGCAGGAACATATTTACTGGTGAAC
TTTGCTCCAAATATAACTCAGGCAATCTCAGCAAGAACAGTACAGTATTACCTTGTCGGATGGCAGTTCCTGATCTATGTGATTTTAGAA
ATATTAATTTTCTGCATTCTCCTGTATTTCTATAAAAGAAAAGGAATGAAGCATATGGTGATTCTGCTAACCCTGGTGGCAATTCTAGCC
TCATTGACTGTTATTTCAGTAAAGGCCGTCTCAGGCATGATCACTTTTTCTGTGATGGATAAAATGCAACTAACTTACCCCATTTTCTAT
ATCATGTTTATCATCATGATAGCATCTTGTGTTTTCCAAGTCAAGTTCCTGAATCAAGCCACGAAACTCTACAATACGACAACAGTGGTG
CCAGTTAATCATATTTTCTTTACAATCAGTGCCATCATTGCAGGTATCATATTTTATCAGGAATTCCTTGGTGCTCCTTTTCTCACTGTA
TTTATATATCTTTTTGGGTGTTTTCTGTCATTCCTTGGTGTATTTTTGGTCACAAGAAATCGAGAAAAGGAACATCTGCAACAGTCTTAT
ATTGATTTTGGAAATATTCCTGGGAAACAAATGTTGGACAAAATACAACCAGATTCACATAGCTTATCCTATGGAACTTTGCCTGATGGA
AGTGACTCAACAAAGAGCCAAAGTGGAGAGAAGAAAGAGGTCTAAATGCTGAGAAGGATGGCTGTTGGCCTGTTATTCGATACCACCTTT
TTAAAAAATTGCACATGTTCAATTTGTGTCAGCAGCTCTTTTATAAGCTAACATGTGCTAGCATTCATTTCAGTCCTTTCCCCCACCTCA
GCGTCTATGGACAATCGGGGACTTCCTAAGCTCTGACAGTCTAATATTTCCATGGAATGTGATTTGGAGTGTTCCCCACACCCTGGACCT
CTCCCTAGTGATTATCTAGCCAGCTACACCTTACTCAGAGCCCGGCTGCTCTAGCAGGAATGTTGCACAGAAACATACATTTGCGGTTTG
GCCACAGGTCGCATAGGTGGCTTCTCCCACGGGTAGTGTCAGTTGCTTCACTTTAAAAAGTCACTTCAGCCCCACAACCTCACTCCCAAA
AGAAAGGTTTGAGAGCGCTCATTTTTTTTCTAAGACACCTTTTATAAGCCTCCCTATAAAAATCTCACCTTTCAAGTACTAAGTTAGAAT
TGCAAGTCATCTTTTCTGAAAACTAATGCTATCAAAGTCCTCCTTTGAAAATTAAGGGTCTCTTTAAAATTAGAATTTATAAATGGCATT
CAGTGATAGTGTACACCAAAATTAAAAGACCTTGACTGGTGGGCTTTTTACGTGTAAGGAAGAGGAAGTTTAAGAAGTAGGACTCTGCTT
GTTTCAGTAGCCCATGTACTAAAATAGGAACAATGCAGAGATTAGCACAGCCCCTGCACAAGGCTGACACATAAATTCATGAAGCGTTAG
AGACAAAAAGTAGGACTAATGTTTGTTTATTTTTTAATAAAAATCTAGAATGGTGATGTTTTCTTCAGCTGTATGATTCTATCATACTTG
AAACTGAAGAAAAATTTAATATCCTATGTCTTTTTTATAGATCTTATAATTTATCAAGTGGATTTATATGTCTTATTCTCCATATAAGTC
TAAAAAATCACATTTAAATTCTTAGTGATAGTTTCACTACACATCATTTCTTCCCAAAGTCATTACCTCAAGCTTTGTAAATTCTTCTAG
ATAAAAGGAGAGTTGTGATTAGAGAACTGAATTTCAGCCATTTAAACCTGTAGACATAGAAAACAACCCAGTGGTCAAACCTGAGCTTCA
AGAGGAAGCCCAAGTCCTCCTGTTTCCTGAATGGCTTTTCCACTCCAATTCATCACATATCTGCTAAGACACATTTGCAGGTAGAATCCA
TAATAATATCTGTTATTTATGATCTACCTAATATTTAAAGGAGAAGAAAAGAAGTAGCCTTCGTTGCAGCCAACATCCAACAATAAGTCC
CACCCTTAATGACATTTCAAAGCCTTCAGATCACTTCTGACATGTCTGTCCAATATCATTCCAATCAATAGTCTTGCATTTAAATAGGTT
GTTTAACTCGGTGGTATTGAGACTGTAACCTTAATGGCTCAGGTCTTTTAGCTTTGTTCTTTGTCATAATCTGCACTCCTGGCCAGACTG
ACCAAACCTGGCTGCAAAGGAAAGAGATTTGAATTGATCACCAATGTATGAAAAATACAGAACCCATGTCTGGCTCCTAAACTCCTGGTA
ATAATTCCCGCCATCGTAGCAAGTGTCCCATGCATTCAGATAAAGCAGTCATAATTTATGGTGTATTTTACCGAATTGGTCCAGCATATT
GGTCCTACAAGGCTCAGCCAAGAAATGTATCTGGTGCCTTAAACTACAGATTTCTGGTGACTCTTAAAACTGGTTTACAAAGATTGAGAA
AACAATTAGATTGAAGAGTTTTGCTTCAAGTAGACCTGCATTCATAGCTAGAGTGCATGAGATTTTCAGCACTGTAGAATTTCACACAGG
CACAAGCATAACACCAGTACTTTAGCAGCCGCCAACAGTTGCATCTATTAAACGTTTTGAGAAATGACATTGACTTATGCACATTTAAGC
AATCAACAATGTTTTAGAAGTCCAGGTAACATATAAAATATATTCAGACCTAGTTTTACTTTCCATATTGTTGCTCCAAAGTAAGGTAAA
TAGGAGTTTTAGTTGTACTGGCCTGTAAGATTTTTTAAATTACACAGTGCATGACAACAACTAAAGCCAACTCAGTCCTTCTCTTGGCAT
TGTGAGTTGAGGACCTTTAGCCAACTGTTAGCTCATCTGACTATCTGTCTAGACCAAGGGTCGGCAAAGTTTTCAGTAAAGACCCACAGA
GTACATATTTTGGAGTTTGTGTTGTCTGTACCAACAGACAGACATGGTGTCTGTCCCAACTACCCAACTCTGCCATTGTAGCACTAAAGC
AGCCATAGACAAGATGTAAACAGAAGAGCATGGCTGTGTTCCAGTAAAACTTTATTTACAGGCCAGGCATGGTGGCTCATGCCTGTAATC
CCAGCACTCTGGGAGGCTGAGGCTGACAGATCATCTGAGGTTAGGAGTTTGGGACCAGCCTGGTCAACATAGTGAAACCCCATCTCTACT
AAAAGTACAAAAATTAGCCAGGCATGACGGTGGGTGCCTGGAGTCCCAGCTACCTGGGAGGCTGAGGCAGGAGAATCACTTGAACCCGGG
AGGTGGAGGTTGCAGTGAGCCGAGATCATGCCATTGCACTCCAGCCTGGGCGACAGAGTAAGACTGTCTCAAAAACAAACAAACAAACAA
ACAAACAAAAACAAGTGGCCAGTCTGTGAGCTATAGTTCCCAACACCTGGTCTAGACTCTTCTGCCCTTGCTCTGCAGCTTCTTTCCTGT
TGATTGGGCATTCAGGGAAGGAGTTTAAAAAGTGACACTCATGGCTCATGACAAATGAGATACTTTGGGAGTGTGGAAACATGGCTTGAT
ATTTGCCTTCAGATATTTTTGCTTATATAAGTTCTAAATGGAAGTGATAAGTTCATTCTTAGGGTCCAAGTTGAAAGGCAGTGGTTCTTT
TGTGAACACCACTAACTACATTCGAAAAGCCTCTCCAATTCCACATTCCAAGTCTATAACAGCTTTGGAAATGAGTAACAATGACCTCTC
ATGTAGTAGATTAAAGCAGAGGCCTTTGCCATATGATTGTTTTTTGGCTTAAATGTTTGCTTGCCCTGTAACTGTAATACTTTGGTTACC

>87576_87576_4_STK3-NIPAL2_STK3_chr8_99538969_ENST00000419617_NIPAL2_chr8_99266315_ENST00000430223_length(amino acids)=809AA_BP=1
MWCPRLGRPVPRLLSSFRPSPSTRSLSLSPAAMEQPPAPKSKLKKLSEDSLTKQPEEVFDVLEKLGEGSYGSVFKAIHKESGQVVAIKQV
PVESDLQEIIKEISIMQQCDSPYVVKYYGSYFKNTDLWIVMEYCGAGSVSDIIRLRNKTLIEDEIATILKSTLKGLEYLHFMRKIHRDIK
AGNILLNTEGHAKLADFGVAGQLTDTMAKRNTVIGTPFWMAPEVIQEIGYNCVADIWSLGITSIEMAEGKPPYADIHPMRAIFMIPTNPP
PTFRKPELWSDDFTDFVKKCLVKNPEQRATATQLLQHPFIKNAKPVSILRDLITEAMEIKAKRHEEQQRELEEEEENSDEDELDSHTMVK
TSVESVGTMRATSTMSEGAQTMIEHNSTMLESDLGTMVINSEDEEEEDGTMKRNATSPQVQRPSFMDYFDKQDFKNKSHENCNQNMHEPF
PMSKNVFPDNWKVPQDGDFDFIHLFGVLLAILGNLVISISLNIQKYSHLQLAQQEHPRPYFKSVLWWGGVLLMAVGETGNFAAYGFAPIT
LIAPLGCVSVTGSAIISVTFLKDNLRASDLLGTTLAFAGTYLLVNFAPNITQAISARTVQYYLVGWQFLIYVILEILIFCILLYFYKRKG
MKHMVILLTLVAILASLTVISVKAVSGMITFSVMDKMQLTYPIFYIMFIIMIASCVFQVKFLNQATKLYNTTTVVPVNHIFFTISAIIAG

--------------------------------------------------------------
>87576_87576_5_STK3-NIPAL2_STK3_chr8_99837743_ENST00000419617_NIPAL2_chr8_99266315_ENST00000341166_length(transcript)=4357nt_BP=167nt
CCGCGGAGTTACGGGAAAGTTGGTCCGAGTTCCCAGAGTTTCCCTCTGTGGTGCCCTAGGCTCGGCCGGCCGGTGCCCCGGCTCCTTTCC
TCCTTTCGGCCTTCGCCGTCCACCAGGTCCCTCTCTCTGTCCCCGGCCGCCATGGAGCAGCCGCCGGCGCCTAAGAGATTCACCTTTTTG
GAGTTTTGCTGGCTATTTTAGGAAACTTGGTGATCAGTATTTCTCTAAATATTCAGAAATATTCTCACCTTCAGCTGGCACAACAAGAGC
ACCCAAGGCCATACTTCAAGAGTGTGCTGTGGTGGGGTGGTGTCCTGCTGATGGCCGTGGGAGAGACGGGGAACTTTGCAGCCTATGGAT
TTGCTCCCATTACTCTGATCGCTCCGTTAGGCTGTGTGTCTGTTACAGGTAGTGCCATTATTTCTGTTACATTTCTGAAAGACAATTTGA
GAGCCTCAGACTTACTCGGTACGACACTGGCATTTGCAGGAACATATTTACTGGTGAACTTTGCTCCAAATATAACTCAGGCAATCTCAG
CAAGAACAGTACAGTATTACCTTGTCGGATGGCAGTTCCTGATCTATGTGATTTTAGAAATATTAATTTTCTGCATTCTCCTGTATTTCT
ATAAAAGAAAAGGAATGAAGCATATGGTGATTCTGCTAACCCTGGTGGCAATTCTAGCCTCATTGACTGTTATTTCAGTAAAGGCCGTCT
CAGGCATGATCACTTTTTCTGTGATGGATAAAATGCAACTAACTTACCCCATTTTCTATATCATGTTTATCATCATGATAGCATCTTGTG
TTTTCCAAGTCAAGTTCCTGAATCAAGCCACGAAACTCTACAATACGACAACAGTGGTGCCAGTTAATCATATTTTCTTTACAATCAGTG
CCATCATTGCAGGTATCATATTTTATCAGGAATTCCTTGGTGCTCCTTTTCTCACTGTATTTATATATCTTTTTGGGTGTTTTCTGTCAT
TCCTTGGTGTATTTTTGGTCACAAGAAATCGAGAAAAGGAACATCTGCAACAGTCTTATATTGATTTTGGAAATATTCCTGACACAACCC
CAGAGAGAAAGGCTTGGAGGGAAACAAATGTTGGACAAAATACAACCAGATTCACATAGCTTATCCTATGGAACTTTGCCTGATGGAAGT
GACTCAACAAAGAGCCAAAGTGGAGAGAAGAAAGAGGTCTAAATGCTGAGAAGGATGGCTGTTGGCCTGTTATTCGATACCACCTTTTTA
AAAAATTGCACATGTTCAATTTGTGTCAGCAGCTCTTTTATAAGCTAACATGTGCTAGCATTCATTTCAGTCCTTTCCCCCACCTCAGCG
TCTATGGACAATCGGGGACTTCCTAAGCTCTGACAGTCTAATATTTCCATGGAATGTGATTTGGAGTGTTCCCCACACCCTGGACCTCTC
CCTAGTGATTATCTAGCCAGCTACACCTTACTCAGAGCCCGGCTGCTCTAGCAGGAATGTTGCACAGAAACATACATTTGCGGTTTGGCC
ACAGGTCGCATAGGTGGCTTCTCCCACGGGTAGTGTCAGTTGCTTCACTTTAAAAAGTCACTTCAGCCCCACAACCTCACTCCCAAAAGA
AAGGTTTGAGAGCGCTCATTTTTTTTCTAAGACACCTTTTATAAGCCTCCCTATAAAAATCTCACCTTTCAAGTACTAAGTTAGAATTGC
AAGTCATCTTTTCTGAAAACTAATGCTATCAAAGTCCTCCTTTGAAAATTAAGGGTCTCTTTAAAATTAGAATTTATAAATGGCATTCAG
TGATAGTGTACACCAAAATTAAAAGACCTTGACTGGTGGGCTTTTTACGTGTAAGGAAGAGGAAGTTTAAGAAGTAGGACTCTGCTTGTT
TCAGTAGCCCATGTACTAAAATAGGAACAATGCAGAGATTAGCACAGCCCCTGCACAAGGCTGACACATAAATTCATGAAGCGTTAGAGA
CAAAAAGTAGGACTAATGTTTGTTTATTTTTTAATAAAAATCTAGAATGGTGATGTTTTCTTCAGCTGTATGATTCTATCATACTTGAAA
CTGAAGAAAAATTTAATATCCTATGTCTTTTTTATAGATCTTATAATTTATCAAGTGGATTTATATGTCTTATTCTCCATATAAGTCTAA
AAAATCACATTTAAATTCTTAGTGATAGTTTCACTACACATCATTTCTTCCCAAAGTCATTACCTCAAGCTTTGTAAATTCTTCTAGATA
AAAGGAGAGTTGTGATTAGAGAACTGAATTTCAGCCATTTAAACCTGTAGACATAGAAAACAACCCAGTGGTCAAACCTGAGCTTCAAGA
GGAAGCCCAAGTCCTCCTGTTTCCTGAATGGCTTTTCCACTCCAATTCATCACATATCTGCTAAGACACATTTGCAGGTAGAATCCATAA
TAATATCTGTTATTTATGATCTACCTAATATTTAAAGGAGAAGAAAAGAAGTAGCCTTCGTTGCAGCCAACATCCAACAATAAGTCCCAC
CCTTAATGACATTTCAAAGCCTTCAGATCACTTCTGACATGTCTGTCCAATATCATTCCAATCAATAGTCTTGCATTTAAATAGGTTGTT
TAACTCGGTGGTATTGAGACTGTAACCTTAATGGCTCAGGTCTTTTAGCTTTGTTCTTTGTCATAATCTGCACTCCTGGCCAGACTGACC
AAACCTGGCTGCAAAGGAAAGAGATTTGAATTGATCACCAATGTATGAAAAATACAGAACCCATGTCTGGCTCCTAAACTCCTGGTAATA
ATTCCCGCCATCGTAGCAAGTGTCCCATGCATTCAGATAAAGCAGTCATAATTTATGGTGTATTTTACCGAATTGGTCCAGCATATTGGT
CCTACAAGGCTCAGCCAAGAAATGTATCTGGTGCCTTAAACTACAGATTTCTGGTGACTCTTAAAACTGGTTTACAAAGATTGAGAAAAC
AATTAGATTGAAGAGTTTTGCTTCAAGTAGACCTGCATTCATAGCTAGAGTGCATGAGATTTTCAGCACTGTAGAATTTCACACAGGCAC
AAGCATAACACCAGTACTTTAGCAGCCGCCAACAGTTGCATCTATTAAACGTTTTGAGAAATGACATTGACTTATGCACATTTAAGCAAT
CAACAATGTTTTAGAAGTCCAGGTAACATATAAAATATATTCAGACCTAGTTTTACTTTCCATATTGTTGCTCCAAAGTAAGGTAAATAG
GAGTTTTAGTTGTACTGGCCTGTAAGATTTTTTAAATTACACAGTGCATGACAACAACTAAAGCCAACTCAGTCCTTCTCTTGGCATTGT
GAGTTGAGGACCTTTAGCCAACTGTTAGCTCATCTGACTATCTGTCTAGACCAAGGGTCGGCAAAGTTTTCAGTAAAGACCCACAGAGTA
CATATTTTGGAGTTTGTGTTGTCTGTACCAACAGACAGACATGGTGTCTGTCCCAACTACCCAACTCTGCCATTGTAGCACTAAAGCAGC
CATAGACAAGATGTAAACAGAAGAGCATGGCTGTGTTCCAGTAAAACTTTATTTACAGGCCAGGCATGGTGGCTCATGCCTGTAATCCCA
GCACTCTGGGAGGCTGAGGCTGACAGATCATCTGAGGTTAGGAGTTTGGGACCAGCCTGGTCAACATAGTGAAACCCCATCTCTACTAAA
AGTACAAAAATTAGCCAGGCATGACGGTGGGTGCCTGGAGTCCCAGCTACCTGGGAGGCTGAGGCAGGAGAATCACTTGAACCCGGGAGG
TGGAGGTTGCAGTGAGCCGAGATCATGCCATTGCACTCCAGCCTGGGCGACAGAGTAAGACTGTCTCAAAAACAAACAAACAAACAAACA
AACAAAAACAAGTGGCCAGTCTGTGAGCTATAGTTCCCAACACCTGGTCTAGACTCTTCTGCCCTTGCTCTGCAGCTTCTTTCCTGTTGA
TTGGGCATTCAGGGAAGGAGTTTAAAAAGTGACACTCATGGCTCATGACAAATGAGATACTTTGGGAGTGTGGAAACATGGCTTGATATT
TGCCTTCAGATATTTTTGCTTATATAAGTTCTAAATGGAAGTGATAAGTTCATTCTTAGGGTCCAAGTTGAAAGGCAGTGGTTCTTTTGT
GAACACCACTAACTACATTCGAAAAGCCTCTCCAATTCCACATTCCAAGTCTATAACAGCTTTGGAAATGAGTAACAATGACCTCTCATG
TAGTAGATTAAAGCAGAGGCCTTTGCCATATGATTGTTTTTTGGCTTAAATGTTTGCTTGCCCTGTAACTGTAATACTTTGGTTACCAGA

>87576_87576_5_STK3-NIPAL2_STK3_chr8_99837743_ENST00000419617_NIPAL2_chr8_99266315_ENST00000341166_length(amino acids)=317AA_BP=
MLAILGNLVISISLNIQKYSHLQLAQQEHPRPYFKSVLWWGGVLLMAVGETGNFAAYGFAPITLIAPLGCVSVTGSAIISVTFLKDNLRA
SDLLGTTLAFAGTYLLVNFAPNITQAISARTVQYYLVGWQFLIYVILEILIFCILLYFYKRKGMKHMVILLTLVAILASLTVISVKAVSG
MITFSVMDKMQLTYPIFYIMFIIMIASCVFQVKFLNQATKLYNTTTVVPVNHIFFTISAIIAGIIFYQEFLGAPFLTVFIYLFGCFLSFL

--------------------------------------------------------------
>87576_87576_6_STK3-NIPAL2_STK3_chr8_99837743_ENST00000419617_NIPAL2_chr8_99266315_ENST00000430223_length(transcript)=4329nt_BP=167nt
CCGCGGAGTTACGGGAAAGTTGGTCCGAGTTCCCAGAGTTTCCCTCTGTGGTGCCCTAGGCTCGGCCGGCCGGTGCCCCGGCTCCTTTCC
TCCTTTCGGCCTTCGCCGTCCACCAGGTCCCTCTCTCTGTCCCCGGCCGCCATGGAGCAGCCGCCGGCGCCTAAGAGATTCACCTTTTTG
GAGTTTTGCTGGCTATTTTAGGAAACTTGGTGATCAGTATTTCTCTAAATATTCAGAAATATTCTCACCTTCAGCTGGCACAACAAGAGC
ACCCAAGGCCATACTTCAAGAGTGTGCTGTGGTGGGGTGGTGTCCTGCTGATGGCCGTGGGAGAGACGGGGAACTTTGCAGCCTATGGAT
TTGCTCCCATTACTCTGATCGCTCCGTTAGGCTGTGTGTCTGTTACAGGTAGTGCCATTATTTCTGTTACATTTCTGAAAGACAATTTGA
GAGCCTCAGACTTACTCGGTACGACACTGGCATTTGCAGGAACATATTTACTGGTGAACTTTGCTCCAAATATAACTCAGGCAATCTCAG
CAAGAACAGTACAGTATTACCTTGTCGGATGGCAGTTCCTGATCTATGTGATTTTAGAAATATTAATTTTCTGCATTCTCCTGTATTTCT
ATAAAAGAAAAGGAATGAAGCATATGGTGATTCTGCTAACCCTGGTGGCAATTCTAGCCTCATTGACTGTTATTTCAGTAAAGGCCGTCT
CAGGCATGATCACTTTTTCTGTGATGGATAAAATGCAACTAACTTACCCCATTTTCTATATCATGTTTATCATCATGATAGCATCTTGTG
TTTTCCAAGTCAAGTTCCTGAATCAAGCCACGAAACTCTACAATACGACAACAGTGGTGCCAGTTAATCATATTTTCTTTACAATCAGTG
CCATCATTGCAGGTATCATATTTTATCAGGAATTCCTTGGTGCTCCTTTTCTCACTGTATTTATATATCTTTTTGGGTGTTTTCTGTCAT
TCCTTGGTGTATTTTTGGTCACAAGAAATCGAGAAAAGGAACATCTGCAACAGTCTTATATTGATTTTGGAAATATTCCTGGGAAACAAA
TGTTGGACAAAATACAACCAGATTCACATAGCTTATCCTATGGAACTTTGCCTGATGGAAGTGACTCAACAAAGAGCCAAAGTGGAGAGA
AGAAAGAGGTCTAAATGCTGAGAAGGATGGCTGTTGGCCTGTTATTCGATACCACCTTTTTAAAAAATTGCACATGTTCAATTTGTGTCA
GCAGCTCTTTTATAAGCTAACATGTGCTAGCATTCATTTCAGTCCTTTCCCCCACCTCAGCGTCTATGGACAATCGGGGACTTCCTAAGC
TCTGACAGTCTAATATTTCCATGGAATGTGATTTGGAGTGTTCCCCACACCCTGGACCTCTCCCTAGTGATTATCTAGCCAGCTACACCT
TACTCAGAGCCCGGCTGCTCTAGCAGGAATGTTGCACAGAAACATACATTTGCGGTTTGGCCACAGGTCGCATAGGTGGCTTCTCCCACG
GGTAGTGTCAGTTGCTTCACTTTAAAAAGTCACTTCAGCCCCACAACCTCACTCCCAAAAGAAAGGTTTGAGAGCGCTCATTTTTTTTCT
AAGACACCTTTTATAAGCCTCCCTATAAAAATCTCACCTTTCAAGTACTAAGTTAGAATTGCAAGTCATCTTTTCTGAAAACTAATGCTA
TCAAAGTCCTCCTTTGAAAATTAAGGGTCTCTTTAAAATTAGAATTTATAAATGGCATTCAGTGATAGTGTACACCAAAATTAAAAGACC
TTGACTGGTGGGCTTTTTACGTGTAAGGAAGAGGAAGTTTAAGAAGTAGGACTCTGCTTGTTTCAGTAGCCCATGTACTAAAATAGGAAC
AATGCAGAGATTAGCACAGCCCCTGCACAAGGCTGACACATAAATTCATGAAGCGTTAGAGACAAAAAGTAGGACTAATGTTTGTTTATT
TTTTAATAAAAATCTAGAATGGTGATGTTTTCTTCAGCTGTATGATTCTATCATACTTGAAACTGAAGAAAAATTTAATATCCTATGTCT
TTTTTATAGATCTTATAATTTATCAAGTGGATTTATATGTCTTATTCTCCATATAAGTCTAAAAAATCACATTTAAATTCTTAGTGATAG
TTTCACTACACATCATTTCTTCCCAAAGTCATTACCTCAAGCTTTGTAAATTCTTCTAGATAAAAGGAGAGTTGTGATTAGAGAACTGAA
TTTCAGCCATTTAAACCTGTAGACATAGAAAACAACCCAGTGGTCAAACCTGAGCTTCAAGAGGAAGCCCAAGTCCTCCTGTTTCCTGAA
TGGCTTTTCCACTCCAATTCATCACATATCTGCTAAGACACATTTGCAGGTAGAATCCATAATAATATCTGTTATTTATGATCTACCTAA
TATTTAAAGGAGAAGAAAAGAAGTAGCCTTCGTTGCAGCCAACATCCAACAATAAGTCCCACCCTTAATGACATTTCAAAGCCTTCAGAT
CACTTCTGACATGTCTGTCCAATATCATTCCAATCAATAGTCTTGCATTTAAATAGGTTGTTTAACTCGGTGGTATTGAGACTGTAACCT
TAATGGCTCAGGTCTTTTAGCTTTGTTCTTTGTCATAATCTGCACTCCTGGCCAGACTGACCAAACCTGGCTGCAAAGGAAAGAGATTTG
AATTGATCACCAATGTATGAAAAATACAGAACCCATGTCTGGCTCCTAAACTCCTGGTAATAATTCCCGCCATCGTAGCAAGTGTCCCAT
GCATTCAGATAAAGCAGTCATAATTTATGGTGTATTTTACCGAATTGGTCCAGCATATTGGTCCTACAAGGCTCAGCCAAGAAATGTATC
TGGTGCCTTAAACTACAGATTTCTGGTGACTCTTAAAACTGGTTTACAAAGATTGAGAAAACAATTAGATTGAAGAGTTTTGCTTCAAGT
AGACCTGCATTCATAGCTAGAGTGCATGAGATTTTCAGCACTGTAGAATTTCACACAGGCACAAGCATAACACCAGTACTTTAGCAGCCG
CCAACAGTTGCATCTATTAAACGTTTTGAGAAATGACATTGACTTATGCACATTTAAGCAATCAACAATGTTTTAGAAGTCCAGGTAACA
TATAAAATATATTCAGACCTAGTTTTACTTTCCATATTGTTGCTCCAAAGTAAGGTAAATAGGAGTTTTAGTTGTACTGGCCTGTAAGAT
TTTTTAAATTACACAGTGCATGACAACAACTAAAGCCAACTCAGTCCTTCTCTTGGCATTGTGAGTTGAGGACCTTTAGCCAACTGTTAG
CTCATCTGACTATCTGTCTAGACCAAGGGTCGGCAAAGTTTTCAGTAAAGACCCACAGAGTACATATTTTGGAGTTTGTGTTGTCTGTAC
CAACAGACAGACATGGTGTCTGTCCCAACTACCCAACTCTGCCATTGTAGCACTAAAGCAGCCATAGACAAGATGTAAACAGAAGAGCAT
GGCTGTGTTCCAGTAAAACTTTATTTACAGGCCAGGCATGGTGGCTCATGCCTGTAATCCCAGCACTCTGGGAGGCTGAGGCTGACAGAT
CATCTGAGGTTAGGAGTTTGGGACCAGCCTGGTCAACATAGTGAAACCCCATCTCTACTAAAAGTACAAAAATTAGCCAGGCATGACGGT
GGGTGCCTGGAGTCCCAGCTACCTGGGAGGCTGAGGCAGGAGAATCACTTGAACCCGGGAGGTGGAGGTTGCAGTGAGCCGAGATCATGC
CATTGCACTCCAGCCTGGGCGACAGAGTAAGACTGTCTCAAAAACAAACAAACAAACAAACAAACAAAAACAAGTGGCCAGTCTGTGAGC
TATAGTTCCCAACACCTGGTCTAGACTCTTCTGCCCTTGCTCTGCAGCTTCTTTCCTGTTGATTGGGCATTCAGGGAAGGAGTTTAAAAA
GTGACACTCATGGCTCATGACAAATGAGATACTTTGGGAGTGTGGAAACATGGCTTGATATTTGCCTTCAGATATTTTTGCTTATATAAG
TTCTAAATGGAAGTGATAAGTTCATTCTTAGGGTCCAAGTTGAAAGGCAGTGGTTCTTTTGTGAACACCACTAACTACATTCGAAAAGCC
TCTCCAATTCCACATTCCAAGTCTATAACAGCTTTGGAAATGAGTAACAATGACCTCTCATGTAGTAGATTAAAGCAGAGGCCTTTGCCA
TATGATTGTTTTTTGGCTTAAATGTTTGCTTGCCCTGTAACTGTAATACTTTGGTTACCAGAATCACTTGAAAACAAATACAATAAAAAA

>87576_87576_6_STK3-NIPAL2_STK3_chr8_99837743_ENST00000419617_NIPAL2_chr8_99266315_ENST00000430223_length(amino acids)=332AA_BP=
MLAILGNLVISISLNIQKYSHLQLAQQEHPRPYFKSVLWWGGVLLMAVGETGNFAAYGFAPITLIAPLGCVSVTGSAIISVTFLKDNLRA
SDLLGTTLAFAGTYLLVNFAPNITQAISARTVQYYLVGWQFLIYVILEILIFCILLYFYKRKGMKHMVILLTLVAILASLTVISVKAVSG
MITFSVMDKMQLTYPIFYIMFIIMIASCVFQVKFLNQATKLYNTTTVVPVNHIFFTISAIIAGIIFYQEFLGAPFLTVFIYLFGCFLSFL

--------------------------------------------------------------

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Fusion Gene PPI Analysis for STK3-NIPAL2


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for STK3-NIPAL2


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for STK3-NIPAL2


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource