FusionGDB Logo

Home

Download

Statistics

Examples

Help

Contact
Center for Computational Systems Medicine
leaf

Fusion Gene Summary

leaf

Fusion Gene ORF analysis

leaf

Fusion Genomic Features

leaf

Fusion Protein Features

leaf

Fusion Gene Sequence

leaf

Fusion Gene PPI analysis

leaf

Related Drugs

leaf

Related Diseases

Fusion gene:STRBP-PRKACB (FusionGDB2 ID:87699)

Fusion Gene Summary for STRBP-PRKACB

check button Fusion gene summary
Fusion gene informationFusion gene name: STRBP-PRKACB
Fusion gene ID: 87699
HgeneTgene
Gene symbol

STRBP

PRKACB

Gene ID

55342

5567

Gene namespermatid perinuclear RNA binding proteinprotein kinase cAMP-activated catalytic subunit beta
SynonymsHEL162|ILF3L|SPNR|p74PKA C-beta|PKACB
Cytomap

9q33.3

1p31.1

Type of geneprotein-codingprotein-coding
Descriptionspermatid perinuclear RNA-binding proteinepididymis luminal protein 162epididymis secretory sperm binding proteincAMP-dependent protein kinase catalytic subunit betacAMP-dependent protein kinase catalytic beta subunit isoform 4abprotein kinase A catalytic subunit betaprotein kinase, cAMP-dependent, beta catalytic subunitprotein kinase, cAMP-dependent, catalytic,
Modification date2020031320200313
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000348403, ENST00000360998, 
ENST00000447404, ENST00000530364, 
ENST00000370680, ENST00000370688, 
ENST00000470673, ENST00000370682, 
ENST00000370685, ENST00000370689, 
ENST00000394838, ENST00000394839, 
Fusion gene scores* DoF score9 X 12 X 9=97211 X 8 X 7=616
# samples 1812
** MAII scorelog2(18/972*10)=-2.43295940727611
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(12/616*10)=-2.35989594508638
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: STRBP [Title/Abstract] AND PRKACB [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointSTRBP(125890493)-PRKACB(84700863), # samples:1
Anticipated loss of major functional domain due to fusion event.STRBP-PRKACB seems lost the major protein functional domain in Tgene partner, which is a cell metabolism gene due to the frame-shifted ORF.
STRBP-PRKACB seems lost the major protein functional domain in Tgene partner, which is a IUPHAR drug target due to the frame-shifted ORF.
STRBP-PRKACB seems lost the major protein functional domain in Tgene partner, which is a kinase due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
TgenePRKACB

GO:0006468

protein phosphorylation

12420224|21880142


check buttonFusion gene breakpoints across STRBP (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across PRKACB (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4STADTCGA-HU-A4GJ-01ASTRBPchr9

125890493

-PRKACBchr1

84700863

+


Top

Fusion Gene ORF analysis for STRBP-PRKACB

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000348403ENST00000370680STRBPchr9

125890493

-PRKACBchr1

84700863

+
5CDS-intronENST00000348403ENST00000370688STRBPchr9

125890493

-PRKACBchr1

84700863

+
5CDS-intronENST00000348403ENST00000470673STRBPchr9

125890493

-PRKACBchr1

84700863

+
5CDS-intronENST00000360998ENST00000370680STRBPchr9

125890493

-PRKACBchr1

84700863

+
5CDS-intronENST00000360998ENST00000370688STRBPchr9

125890493

-PRKACBchr1

84700863

+
5CDS-intronENST00000360998ENST00000470673STRBPchr9

125890493

-PRKACBchr1

84700863

+
5CDS-intronENST00000447404ENST00000370680STRBPchr9

125890493

-PRKACBchr1

84700863

+
5CDS-intronENST00000447404ENST00000370688STRBPchr9

125890493

-PRKACBchr1

84700863

+
5CDS-intronENST00000447404ENST00000470673STRBPchr9

125890493

-PRKACBchr1

84700863

+
Frame-shiftENST00000348403ENST00000370682STRBPchr9

125890493

-PRKACBchr1

84700863

+
Frame-shiftENST00000348403ENST00000370685STRBPchr9

125890493

-PRKACBchr1

84700863

+
Frame-shiftENST00000348403ENST00000370689STRBPchr9

125890493

-PRKACBchr1

84700863

+
Frame-shiftENST00000348403ENST00000394838STRBPchr9

125890493

-PRKACBchr1

84700863

+
Frame-shiftENST00000348403ENST00000394839STRBPchr9

125890493

-PRKACBchr1

84700863

+
Frame-shiftENST00000360998ENST00000370682STRBPchr9

125890493

-PRKACBchr1

84700863

+
Frame-shiftENST00000360998ENST00000370685STRBPchr9

125890493

-PRKACBchr1

84700863

+
Frame-shiftENST00000360998ENST00000370689STRBPchr9

125890493

-PRKACBchr1

84700863

+
Frame-shiftENST00000360998ENST00000394838STRBPchr9

125890493

-PRKACBchr1

84700863

+
Frame-shiftENST00000360998ENST00000394839STRBPchr9

125890493

-PRKACBchr1

84700863

+
In-frameENST00000447404ENST00000370682STRBPchr9

125890493

-PRKACBchr1

84700863

+
In-frameENST00000447404ENST00000370685STRBPchr9

125890493

-PRKACBchr1

84700863

+
In-frameENST00000447404ENST00000370689STRBPchr9

125890493

-PRKACBchr1

84700863

+
In-frameENST00000447404ENST00000394838STRBPchr9

125890493

-PRKACBchr1

84700863

+
In-frameENST00000447404ENST00000394839STRBPchr9

125890493

-PRKACBchr1

84700863

+
intron-3CDSENST00000530364ENST00000370682STRBPchr9

125890493

-PRKACBchr1

84700863

+
intron-3CDSENST00000530364ENST00000370685STRBPchr9

125890493

-PRKACBchr1

84700863

+
intron-3CDSENST00000530364ENST00000370689STRBPchr9

125890493

-PRKACBchr1

84700863

+
intron-3CDSENST00000530364ENST00000394838STRBPchr9

125890493

-PRKACBchr1

84700863

+
intron-3CDSENST00000530364ENST00000394839STRBPchr9

125890493

-PRKACBchr1

84700863

+
intron-intronENST00000530364ENST00000370680STRBPchr9

125890493

-PRKACBchr1

84700863

+
intron-intronENST00000530364ENST00000370688STRBPchr9

125890493

-PRKACBchr1

84700863

+
intron-intronENST00000530364ENST00000470673STRBPchr9

125890493

-PRKACBchr1

84700863

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000447404STRBPchr9125890493-ENST00000370689PRKACBchr184700863+556622473052251648
ENST00000447404STRBPchr9125890493-ENST00000370685PRKACBchr184700863+556622473052251648
ENST00000447404STRBPchr9125890493-ENST00000394838PRKACBchr184700863+555722473052251648
ENST00000447404STRBPchr9125890493-ENST00000370682PRKACBchr184700863+555722473052251648
ENST00000447404STRBPchr9125890493-ENST00000394839PRKACBchr184700863+556622473052251648

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000447404ENST00000370689STRBPchr9125890493-PRKACBchr184700863+0.0001422940.99985766
ENST00000447404ENST00000370685STRBPchr9125890493-PRKACBchr184700863+0.0001422940.99985766
ENST00000447404ENST00000394838STRBPchr9125890493-PRKACBchr184700863+0.0001419390.999858
ENST00000447404ENST00000370682STRBPchr9125890493-PRKACBchr184700863+0.0001419390.999858
ENST00000447404ENST00000394839STRBPchr9125890493-PRKACBchr184700863+0.0001422940.99985766

Top

Fusion Genomic Features for STRBP-PRKACB


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
STRBPchr9125890492-PRKACBchr184700862+0.0246067810.97539324
STRBPchr9125890492-PRKACBchr184700862+0.0246067810.97539324

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

Top

Fusion Protein Features for STRBP-PRKACB


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr9:125890493/chr1:84700863)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneSTRBPchr9:125890493chr1:84700863ENST00000348403-1819584_587647673.0Compositional biasNote=Poly-Lys
HgeneSTRBPchr9:125890493chr1:84700863ENST00000360998-1819584_587633659.0Compositional biasNote=Poly-Lys
HgeneSTRBPchr9:125890493chr1:84700863ENST00000447404-1718584_587647673.0Compositional biasNote=Poly-Lys
HgeneSTRBPchr9:125890493chr1:84700863ENST00000348403-1819387_453647673.0DomainDRBM 1
HgeneSTRBPchr9:125890493chr1:84700863ENST00000348403-1819510_576647673.0DomainDRBM 2
HgeneSTRBPchr9:125890493chr1:84700863ENST00000348403-18195_363647673.0DomainDZF
HgeneSTRBPchr9:125890493chr1:84700863ENST00000360998-1819387_453633659.0DomainDRBM 1
HgeneSTRBPchr9:125890493chr1:84700863ENST00000360998-1819510_576633659.0DomainDRBM 2
HgeneSTRBPchr9:125890493chr1:84700863ENST00000360998-18195_363633659.0DomainDZF
HgeneSTRBPchr9:125890493chr1:84700863ENST00000447404-1718387_453647673.0DomainDRBM 1
HgeneSTRBPchr9:125890493chr1:84700863ENST00000447404-1718510_576647673.0DomainDRBM 2
HgeneSTRBPchr9:125890493chr1:84700863ENST00000447404-17185_363647673.0DomainDZF
TgenePRKACBchr9:125890493chr1:84700863ENST0000037068809299_3510258.0DomainAGC-kinase C-terminal
TgenePRKACBchr9:125890493chr1:84700863ENST000003706880944_2980258.0DomainProtein kinase
TgenePRKACBchr9:125890493chr1:84700863ENST00000394839911299_351280322.0DomainAGC-kinase C-terminal
TgenePRKACBchr9:125890493chr1:84700863ENST000003706880950_580258.0Nucleotide bindingATP

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgenePRKACBchr9:125890493chr1:84700863ENST000003706821012299_351314356.0DomainAGC-kinase C-terminal
TgenePRKACBchr9:125890493chr1:84700863ENST00000370682101244_298314356.0DomainProtein kinase
TgenePRKACBchr9:125890493chr1:84700863ENST00000370685810299_351357399.0DomainAGC-kinase C-terminal
TgenePRKACBchr9:125890493chr1:84700863ENST0000037068581044_298357399.0DomainProtein kinase
TgenePRKACBchr9:125890493chr1:84700863ENST00000370689810299_351310352.0DomainAGC-kinase C-terminal
TgenePRKACBchr9:125890493chr1:84700863ENST0000037068981044_298310352.0DomainProtein kinase
TgenePRKACBchr9:125890493chr1:84700863ENST000003948381113299_351317359.0DomainAGC-kinase C-terminal
TgenePRKACBchr9:125890493chr1:84700863ENST00000394838111344_298317359.0DomainProtein kinase
TgenePRKACBchr9:125890493chr1:84700863ENST0000039483991144_298280322.0DomainProtein kinase
TgenePRKACBchr9:125890493chr1:84700863ENST00000370682101250_58314356.0Nucleotide bindingATP
TgenePRKACBchr9:125890493chr1:84700863ENST0000037068581050_58357399.0Nucleotide bindingATP
TgenePRKACBchr9:125890493chr1:84700863ENST0000037068981050_58310352.0Nucleotide bindingATP
TgenePRKACBchr9:125890493chr1:84700863ENST00000394838111350_58317359.0Nucleotide bindingATP
TgenePRKACBchr9:125890493chr1:84700863ENST0000039483991150_58280322.0Nucleotide bindingATP


Top

Fusion Gene Sequence for STRBP-PRKACB


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>87699_87699_1_STRBP-PRKACB_STRBP_chr9_125890493_ENST00000447404_PRKACB_chr1_84700863_ENST00000370682_length(transcript)=5557nt_BP=2247nt
CCGGAGCCGCGAGCGCCACCAGGGCAGCAGCCGCCGCAGCCGCCGCCGCTGGGCAGAGGAGCCGGAGACGCGAGCGGGCGAGGTGGCGGC
GGCGGCGGAGCGGGAGCGGGTACCGGGCGCGGGCAGAGCGCGGCGGCGCGGGTGTGTTCCAGAGAACAAGCCTTCAGACATTTGCTATAT
TGACGCTGAGCTGTCAGGGGACTCAGGCTTATGAGGAGGTATTGTTACACAAAACAGTGTCTAGTGAAGACGACAAGAAAGAGGGGAAAG
GATCGGAAAAAGAAGCTAAAATACTATAGAAAACCATGAGATCTATTCGATCTTTTGCTAATGATGATCGCCATGTTATGGTGAAACATT
CAACAATCTATCCATCTCCGGAGGAACTTGAAGCTGTTCAGAATATGGTATCTACTGTTGAATGTGCTCTTAAACATGTCTCAGATTGGT
TGGATGAAACAAATAAAGGCACAAAAACAGAGGGTGAGACAGAAGTGAAGAAAGATGAGGCCGGAGAAAACTATTCCAAGGATCAAGGTG
GTCGGACATTGTGTGGTGTAATGAGGATTGGCCTGGTTGCAAAAGGCTTGCTGATTAAAGATGATATGGACTTGGAGCTGGTTTTAATGT
GCAAAGACAAACCCACAGAGACCCTGTTAAATACAGTCAAAGATAATCTTCCTATTCAGATTCAGAAACTCACAGAAGAGAAATATCAAG
TGGAACAATGTGTAAATGAGGCATCTATTATAATTCGGAATACAAAAGAGCCCACGCTAACTTTGAAGGTGATACTTACCTCACCTCTAA
TTAGGGACGAATTGGAGAAGAAGGATGGAGAAAATGTTTCGATGAAAGATCCTCCGGACTTATTGGACAGGCAGAAATGCCTGAACGCCT
TGGCGTCTCTTCGACATGCCAAATGGTTTCAGGCAAGGGCAAATGGATTAAAATCATGTGTAATTGTCCTCCGCATTCTGCGTGATTTGT
GCAACAGAGTCCCCACATGGGCACCATTGAAAGGATGGCCACTAGAACTTATATGTGAAAAGTCTATAGGTACTTGTAATAGACCTTTGG
GCGCTGGGGAGGCCTTGAGACGAGTAATGGAGTGTTTGGCATCTGGAATACTACTTCCTGGGGGTCCTGGTCTTCATGATCCTTGTGAGC
GAGACCCAACAGATGCTCTGAGCTATATGACCATCCAGCAAAAAGAAGATATTACCCACAGTGCACAGCATGCACTCAGACTATCAGCCT
TTGGCCAGATTTACAAAGTGCTGGAGATGGACCCCCTTCCATCTAGTAAGCCTTTTCAGAAGTATTCCTGGTCAGTTACTGATAAAGAAG
GTGCTGGGTCTTCAGCTCTAAAGAGGCCATTTGAAGATGGATTAGGGGATGATAAAGACCCCAACAAGAAGATGAAACGAAACTTAAGGA
AAATTCTGGATAGTAAAGCAATAGACCTTATGAATGCACTAATGAGGCTAAATCAGATCAGGCCTGGGCTTCAGTATAAGCTCCTATCTC
AGTCTGGCCCCGTTCATGCCCCAGTCTTCACAATGTCTGTAGATGTGGATGGCACAACATATGAAGCCTCAGGACCATCCAAGAAAACAG
CAAAACTTCACGTAGCGGTGAAGGTATTGCAGGCAATGGGATATCCAACAGGCTTTGATGCAGATATTGAATGTATGAGTTCCGATGAAA
AATCAGATAATGAAAGTAAAAATGAAACAGTGTCTTCAAACTCAAGCAATAATACTGGAAATTCTACAACTGAAACCTCCAGTACCTTAG
AGGTAAGAACTCAGGGCCCTATCCTCACAGCAAGTGGCAAAAACCCTGTAATGGAGCTCAATGAAAAAAGAAGAGGTCTCAAGTATGAAC
TCATCTCAGAGACTGGTGGAAGCCATGACAAGCGCTTTGTAATGGAGGTAGAAGTAGATGGACAGAAATTCAGAGGCGCAGGTCCAAATA
AGAAAGTGGCAAAGGCGAGTGCAGCTTTAGCTGCCTTGGAGAAACTGTTTTCTGGACCCAATGCGGCAAATAATAAGAAAAAGAAGATTA
TCCCTCAGGCAAAGGGCGTTGTGAATACAGCTGTGTCTGCAGCAGTCCAAGCTGTTCGGGGCAGAGGAAGAGGAACTCTAACAAGGGGAG
CTTTTGTTGGGGCGACAGCTGCTCCTGGCTACATAGCTCCAGGCTATGGAACACCATATGGTTACAGCACAGCTGCCCCTGCCTATGGTT
GAAGCTCCATTCATACCAAAGTTTAGAGGCTCTGGAGATACCAGCAACTTTGATGACTATGAAGAAGAAGATATCCGTGTCTCTATAACA
GAAAAATGTGCAAAAGAATTTGGTGAATTTTAAAGAGGAACAAGATGACATCTGAGCTCACACTCAGTGTTTGCACTCTGTTGAGAGATA
AGGTAGAGCTGAGACCGTCCTTGTTGAAGCAGTTACCTAGTTCCTTCATTCCAACGACTGAGTGAGGTCTTTATTGCCATCATCCCGTGT
GCGCACTCTGCATCCACCTATGTAACAAGGCACCGCTAAGCAAGCATTGTCTGTGCCATAACACAGTACTAGACCACTTTCTTACTTCTC
TTTGGGTTGTCTTTCTCCTCTCCTATATCCATTTCTTCCTTTTCCAATTTCATTGGTTTTCTCTAAACAGTGCTCCATTTTATTTTGTTG
GTGTTTCAGATGGGCAGTGTTATGGCTACGTGATATTTGAAGGGAAGGATAAGTGTTGCTTTCAGTAGTTATTGCCAATATTGTTGTTGG
TCAATGGCTTGAAGATAAACTTTCTAATAATTATTATTTCTTTGAGTAGCTCAGACTTGGTTTTGCCAAAACTCTTGGTAATTTTTGAAG
ATAGACTGTCTTATCACCAAGGAAATTTATACAAATTAAGACTAACTTTCTTGGAATTCACTATTCTGGCAATAAATTTTGGTAGACTAA
TACAGTACAGCTAGACCCAGAAATTTGGAAGGCTGTAGATCAGAGGTTCTAGTTCCCTTTCCCTCCTTTTATATCCTCCTCTCCTTGAGT
AATGAAGTGACCAGCCTGTGTAGTGTGACAAACGTGTCTCATTCAGCAGGAAAAACTAATGATATGGATCATCACCCAGATTCTCTCACT
TGGTACCAGCATTTCTGTAGGTATTAGAGAAGAGTTCTAAGTTTTCTAAACCTTAACTGTTCCTTAAGGATTTTAGCCAGTATTTTAATA
GAACATGATTAATGAAAGTGACAAATTTTAAATTTTCTCTAATAGTCCTCATCATAAACTTTTTAAAGGAAAATAAGCAAACTAAAAAGA
ACATTGGTTTAGATAAATACTTATACTTTGCAAAGTCAAAAATGGCTTGATTTTTGGAAACAATATAGAGGTATTCATATTTAAATGAGG
GTTTACATTTGTTTTGTTTTGTAACCGTTAAAAAGAAGTTGTTTCCAGCTAATTATTGTGGTGTACTATATTTGTGAGCCTAGGGTAGGG
GCACTGCTGCAACTTCTGCTTTCATCCCATGCCTCATCAATGAGGAAAGGGAACAAAGTGTATAAAACTGCCACAATTGTATTTTAATTT
TGAGGTATGATATTTTCAGATATTTCATAATTTCTAACCTCTGTTCTCTCAGTAAACAGAATGTCTGATCGATCATGCAGATACAATGTT
GGTATTTGAGAGGTTAGTTTTTTTCCTACACTTTTTTTTGCCAACTGACTTAACAACATTGCTGTCAGGTGGAAATTTCAAGCACTTTTG
CACATTTAGTTCAGTGTTTGTTGAGAATCCATGGCTTAACCCACTTGTTTTGCTATTTTTTTCTTTGCTTTTAATTTTCCCCATCTGATT
TTATCTCTGCGTTTCAGTGACCTACCTTAAAACAACACACGAGAAGAGTTAAACTGGGTTCATTTTAATGATCAATTTACCTGCATATAA
AATTTATTTTTAATCAAGCTGATCTTAATGTATATAATCATTCTATTTGCTTTATTATCGGTGCAGGTAGGTCATTAACACCACTTCTTT
TCATCTGTACCACACCCTGGTGAAACCTTTGAAGACATAAAAAAAACCTGTCTGAGATGTTCTTTCTACCAATCTATATGTCTTTCGGTT
ATCAAGTGTTTCTGCATGGTAATGTCATGTAAATGCTGATATTGATTTCACTGGTCCATCTATATTTAAAACGTGCAAGAAAAAAATAAA
ATACTCTGCTCTAGCAAGTTTTGTGTAACAAAGGCATATCGTCATGTTAATAAATTTAAAACATCATTCGTATAAAATATTTTAATTTTC
TTGTATTTCATTTAGACCCAAGAACATGCTGACCAATGTGTTCTATATGTAAACTACAAATTCTATGGTAGCTTTGTTGTATATTATTGT
AAAATTATTTTAATAAGTCATGGGGATGACAATTTGATTATTACAATTTAGTTTTCAGTAATCAAAAAGATTTCTATGAATTCTAAAAAA
TATTTTTTTCTATGAAATTACTAGTGCCCAGCTGTAGAATCTACCTTAGGTAGATGATCCCTAGACATACGTTGGTTTTGAGGGCTATTC
AGCCATTCCATTTTACTCTCTATTTAAAGGCCGTGAGCAAGCTTGTCATGAGCAAATATGTCAAGGGAGTCAATTTCTGACCAATCAAGT
ACACTAAATTAGAATATTTTTAAAGTATGTAACATTCCCAGTTTCAGCCACAATTTAGCCAAGAATAAGATAAAAACTTGAATAAGAAGT
AAGTAGCATAAATCAGTATTTAACCTAAAATTACATATTTGAAACAGAAGATATTATGTTATGCTCAGTAAATAATTAAGAGATGGCATT
GTGTAAGAAGGAGCCCTAGACTGAAAGTCAAGACATCTGAATTTCAGGCTGGAAAACTATCAGTATGATCTCAGCCTCAGTTCTCTTGTC
TGTAAAATGGAAGAACTGGATTAGGCAGTTTGTAAGATTCCTCCTAACTTTCACAGTCGATGACAAGATTGTCTTTTTATCTGATATTTT
GAAGGGTATATTGCTTTGAAGTAAGTCTCAATAAGGCAATATATTTTAGGGCATCTTTCTTCTTATCTCTGACAGTGTTCTTAAAATTAT
TTGAATATCATAAGAGCCTTGGTGTCTGTCCTAATTCCTTTCTCACTCACCGATGCTGAATACCCAGTTGAATCAAACTGTCAACCTACC
AAAAACGATATTGTGGCTTATGGGTATTGCTGTCTCATTCTTGGTATATTCTTGTGTTAACTGCCCATTGGCCTGAAAATACTCATTGTA
AGCCTGAAAAAAAAAATCTTTCCCACTGTTTTTTCTGCTTGTTGTAAGAATCAAATGAAATAATGTATGTGAAAGCACCTTGTAAACTGT
AACCTATCAATGTAAAATGTTAAGGTGTGTTGTTATTTCATTAATTACTTCTTTGTTTAGAATGGAATTTCCTATGCACTACTGTAGCTA

>87699_87699_1_STRBP-PRKACB_STRBP_chr9_125890493_ENST00000447404_PRKACB_chr1_84700863_ENST00000370682_length(amino acids)=648AA_BP=
MRSIRSFANDDRHVMVKHSTIYPSPEELEAVQNMVSTVECALKHVSDWLDETNKGTKTEGETEVKKDEAGENYSKDQGGRTLCGVMRIGL
VAKGLLIKDDMDLELVLMCKDKPTETLLNTVKDNLPIQIQKLTEEKYQVEQCVNEASIIIRNTKEPTLTLKVILTSPLIRDELEKKDGEN
VSMKDPPDLLDRQKCLNALASLRHAKWFQARANGLKSCVIVLRILRDLCNRVPTWAPLKGWPLELICEKSIGTCNRPLGAGEALRRVMEC
LASGILLPGGPGLHDPCERDPTDALSYMTIQQKEDITHSAQHALRLSAFGQIYKVLEMDPLPSSKPFQKYSWSVTDKEGAGSSALKRPFE
DGLGDDKDPNKKMKRNLRKILDSKAIDLMNALMRLNQIRPGLQYKLLSQSGPVHAPVFTMSVDVDGTTYEASGPSKKTAKLHVAVKVLQA
MGYPTGFDADIECMSSDEKSDNESKNETVSSNSSNNTGNSTTETSSTLEVRTQGPILTASGKNPVMELNEKRRGLKYELISETGGSHDKR
FVMEVEVDGQKFRGAGPNKKVAKASAALAALEKLFSGPNAANNKKKKIIPQAKGVVNTAVSAAVQAVRGRGRGTLTRGAFVGATAAPGYI

--------------------------------------------------------------
>87699_87699_2_STRBP-PRKACB_STRBP_chr9_125890493_ENST00000447404_PRKACB_chr1_84700863_ENST00000370685_length(transcript)=5566nt_BP=2247nt
CCGGAGCCGCGAGCGCCACCAGGGCAGCAGCCGCCGCAGCCGCCGCCGCTGGGCAGAGGAGCCGGAGACGCGAGCGGGCGAGGTGGCGGC
GGCGGCGGAGCGGGAGCGGGTACCGGGCGCGGGCAGAGCGCGGCGGCGCGGGTGTGTTCCAGAGAACAAGCCTTCAGACATTTGCTATAT
TGACGCTGAGCTGTCAGGGGACTCAGGCTTATGAGGAGGTATTGTTACACAAAACAGTGTCTAGTGAAGACGACAAGAAAGAGGGGAAAG
GATCGGAAAAAGAAGCTAAAATACTATAGAAAACCATGAGATCTATTCGATCTTTTGCTAATGATGATCGCCATGTTATGGTGAAACATT
CAACAATCTATCCATCTCCGGAGGAACTTGAAGCTGTTCAGAATATGGTATCTACTGTTGAATGTGCTCTTAAACATGTCTCAGATTGGT
TGGATGAAACAAATAAAGGCACAAAAACAGAGGGTGAGACAGAAGTGAAGAAAGATGAGGCCGGAGAAAACTATTCCAAGGATCAAGGTG
GTCGGACATTGTGTGGTGTAATGAGGATTGGCCTGGTTGCAAAAGGCTTGCTGATTAAAGATGATATGGACTTGGAGCTGGTTTTAATGT
GCAAAGACAAACCCACAGAGACCCTGTTAAATACAGTCAAAGATAATCTTCCTATTCAGATTCAGAAACTCACAGAAGAGAAATATCAAG
TGGAACAATGTGTAAATGAGGCATCTATTATAATTCGGAATACAAAAGAGCCCACGCTAACTTTGAAGGTGATACTTACCTCACCTCTAA
TTAGGGACGAATTGGAGAAGAAGGATGGAGAAAATGTTTCGATGAAAGATCCTCCGGACTTATTGGACAGGCAGAAATGCCTGAACGCCT
TGGCGTCTCTTCGACATGCCAAATGGTTTCAGGCAAGGGCAAATGGATTAAAATCATGTGTAATTGTCCTCCGCATTCTGCGTGATTTGT
GCAACAGAGTCCCCACATGGGCACCATTGAAAGGATGGCCACTAGAACTTATATGTGAAAAGTCTATAGGTACTTGTAATAGACCTTTGG
GCGCTGGGGAGGCCTTGAGACGAGTAATGGAGTGTTTGGCATCTGGAATACTACTTCCTGGGGGTCCTGGTCTTCATGATCCTTGTGAGC
GAGACCCAACAGATGCTCTGAGCTATATGACCATCCAGCAAAAAGAAGATATTACCCACAGTGCACAGCATGCACTCAGACTATCAGCCT
TTGGCCAGATTTACAAAGTGCTGGAGATGGACCCCCTTCCATCTAGTAAGCCTTTTCAGAAGTATTCCTGGTCAGTTACTGATAAAGAAG
GTGCTGGGTCTTCAGCTCTAAAGAGGCCATTTGAAGATGGATTAGGGGATGATAAAGACCCCAACAAGAAGATGAAACGAAACTTAAGGA
AAATTCTGGATAGTAAAGCAATAGACCTTATGAATGCACTAATGAGGCTAAATCAGATCAGGCCTGGGCTTCAGTATAAGCTCCTATCTC
AGTCTGGCCCCGTTCATGCCCCAGTCTTCACAATGTCTGTAGATGTGGATGGCACAACATATGAAGCCTCAGGACCATCCAAGAAAACAG
CAAAACTTCACGTAGCGGTGAAGGTATTGCAGGCAATGGGATATCCAACAGGCTTTGATGCAGATATTGAATGTATGAGTTCCGATGAAA
AATCAGATAATGAAAGTAAAAATGAAACAGTGTCTTCAAACTCAAGCAATAATACTGGAAATTCTACAACTGAAACCTCCAGTACCTTAG
AGGTAAGAACTCAGGGCCCTATCCTCACAGCAAGTGGCAAAAACCCTGTAATGGAGCTCAATGAAAAAAGAAGAGGTCTCAAGTATGAAC
TCATCTCAGAGACTGGTGGAAGCCATGACAAGCGCTTTGTAATGGAGGTAGAAGTAGATGGACAGAAATTCAGAGGCGCAGGTCCAAATA
AGAAAGTGGCAAAGGCGAGTGCAGCTTTAGCTGCCTTGGAGAAACTGTTTTCTGGACCCAATGCGGCAAATAATAAGAAAAAGAAGATTA
TCCCTCAGGCAAAGGGCGTTGTGAATACAGCTGTGTCTGCAGCAGTCCAAGCTGTTCGGGGCAGAGGAAGAGGAACTCTAACAAGGGGAG
CTTTTGTTGGGGCGACAGCTGCTCCTGGCTACATAGCTCCAGGCTATGGAACACCATATGGTTACAGCACAGCTGCCCCTGCCTATGGTT
GAAGCTCCATTCATACCAAAGTTTAGAGGCTCTGGAGATACCAGCAACTTTGATGACTATGAAGAAGAAGATATCCGTGTCTCTATAACA
GAAAAATGTGCAAAAGAATTTGGTGAATTTTAAAGAGGAACAAGATGACATCTGAGCTCACACTCAGTGTTTGCACTCTGTTGAGAGATA
AGGTAGAGCTGAGACCGTCCTTGTTGAAGCAGTTACCTAGTTCCTTCATTCCAACGACTGAGTGAGGTCTTTATTGCCATCATCCCGTGT
GCGCACTCTGCATCCACCTATGTAACAAGGCACCGCTAAGCAAGCATTGTCTGTGCCATAACACAGTACTAGACCACTTTCTTACTTCTC
TTTGGGTTGTCTTTCTCCTCTCCTATATCCATTTCTTCCTTTTCCAATTTCATTGGTTTTCTCTAAACAGTGCTCCATTTTATTTTGTTG
GTGTTTCAGATGGGCAGTGTTATGGCTACGTGATATTTGAAGGGAAGGATAAGTGTTGCTTTCAGTAGTTATTGCCAATATTGTTGTTGG
TCAATGGCTTGAAGATAAACTTTCTAATAATTATTATTTCTTTGAGTAGCTCAGACTTGGTTTTGCCAAAACTCTTGGTAATTTTTGAAG
ATAGACTGTCTTATCACCAAGGAAATTTATACAAATTAAGACTAACTTTCTTGGAATTCACTATTCTGGCAATAAATTTTGGTAGACTAA
TACAGTACAGCTAGACCCAGAAATTTGGAAGGCTGTAGATCAGAGGTTCTAGTTCCCTTTCCCTCCTTTTATATCCTCCTCTCCTTGAGT
AATGAAGTGACCAGCCTGTGTAGTGTGACAAACGTGTCTCATTCAGCAGGAAAAACTAATGATATGGATCATCACCCAGATTCTCTCACT
TGGTACCAGCATTTCTGTAGGTATTAGAGAAGAGTTCTAAGTTTTCTAAACCTTAACTGTTCCTTAAGGATTTTAGCCAGTATTTTAATA
GAACATGATTAATGAAAGTGACAAATTTTAAATTTTCTCTAATAGTCCTCATCATAAACTTTTTAAAGGAAAATAAGCAAACTAAAAAGA
ACATTGGTTTAGATAAATACTTATACTTTGCAAAGTCAAAAATGGCTTGATTTTTGGAAACAATATAGAGGTATTCATATTTAAATGAGG
GTTTACATTTGTTTTGTTTTGTAACCGTTAAAAAGAAGTTGTTTCCAGCTAATTATTGTGGTGTACTATATTTGTGAGCCTAGGGTAGGG
GCACTGCTGCAACTTCTGCTTTCATCCCATGCCTCATCAATGAGGAAAGGGAACAAAGTGTATAAAACTGCCACAATTGTATTTTAATTT
TGAGGTATGATATTTTCAGATATTTCATAATTTCTAACCTCTGTTCTCTCAGTAAACAGAATGTCTGATCGATCATGCAGATACAATGTT
GGTATTTGAGAGGTTAGTTTTTTTCCTACACTTTTTTTTGCCAACTGACTTAACAACATTGCTGTCAGGTGGAAATTTCAAGCACTTTTG
CACATTTAGTTCAGTGTTTGTTGAGAATCCATGGCTTAACCCACTTGTTTTGCTATTTTTTTCTTTGCTTTTAATTTTCCCCATCTGATT
TTATCTCTGCGTTTCAGTGACCTACCTTAAAACAACACACGAGAAGAGTTAAACTGGGTTCATTTTAATGATCAATTTACCTGCATATAA
AATTTATTTTTAATCAAGCTGATCTTAATGTATATAATCATTCTATTTGCTTTATTATCGGTGCAGGTAGGTCATTAACACCACTTCTTT
TCATCTGTACCACACCCTGGTGAAACCTTTGAAGACATAAAAAAAACCTGTCTGAGATGTTCTTTCTACCAATCTATATGTCTTTCGGTT
ATCAAGTGTTTCTGCATGGTAATGTCATGTAAATGCTGATATTGATTTCACTGGTCCATCTATATTTAAAACGTGCAAGAAAAAAATAAA
ATACTCTGCTCTAGCAAGTTTTGTGTAACAAAGGCATATCGTCATGTTAATAAATTTAAAACATCATTCGTATAAAATATTTTAATTTTC
TTGTATTTCATTTAGACCCAAGAACATGCTGACCAATGTGTTCTATATGTAAACTACAAATTCTATGGTAGCTTTGTTGTATATTATTGT
AAAATTATTTTAATAAGTCATGGGGATGACAATTTGATTATTACAATTTAGTTTTCAGTAATCAAAAAGATTTCTATGAATTCTAAAAAA
TATTTTTTTCTATGAAATTACTAGTGCCCAGCTGTAGAATCTACCTTAGGTAGATGATCCCTAGACATACGTTGGTTTTGAGGGCTATTC
AGCCATTCCATTTTACTCTCTATTTAAAGGCCGTGAGCAAGCTTGTCATGAGCAAATATGTCAAGGGAGTCAATTTCTGACCAATCAAGT
ACACTAAATTAGAATATTTTTAAAGTATGTAACATTCCCAGTTTCAGCCACAATTTAGCCAAGAATAAGATAAAAACTTGAATAAGAAGT
AAGTAGCATAAATCAGTATTTAACCTAAAATTACATATTTGAAACAGAAGATATTATGTTATGCTCAGTAAATAATTAAGAGATGGCATT
GTGTAAGAAGGAGCCCTAGACTGAAAGTCAAGACATCTGAATTTCAGGCTGGAAAACTATCAGTATGATCTCAGCCTCAGTTCTCTTGTC
TGTAAAATGGAAGAACTGGATTAGGCAGTTTGTAAGATTCCTCCTAACTTTCACAGTCGATGACAAGATTGTCTTTTTATCTGATATTTT
GAAGGGTATATTGCTTTGAAGTAAGTCTCAATAAGGCAATATATTTTAGGGCATCTTTCTTCTTATCTCTGACAGTGTTCTTAAAATTAT
TTGAATATCATAAGAGCCTTGGTGTCTGTCCTAATTCCTTTCTCACTCACCGATGCTGAATACCCAGTTGAATCAAACTGTCAACCTACC
AAAAACGATATTGTGGCTTATGGGTATTGCTGTCTCATTCTTGGTATATTCTTGTGTTAACTGCCCATTGGCCTGAAAATACTCATTGTA
AGCCTGAAAAAAAAAATCTTTCCCACTGTTTTTTCTGCTTGTTGTAAGAATCAAATGAAATAATGTATGTGAAAGCACCTTGTAAACTGT
AACCTATCAATGTAAAATGTTAAGGTGTGTTGTTATTTCATTAATTACTTCTTTGTTTAGAATGGAATTTCCTATGCACTACTGTAGCTA

>87699_87699_2_STRBP-PRKACB_STRBP_chr9_125890493_ENST00000447404_PRKACB_chr1_84700863_ENST00000370685_length(amino acids)=648AA_BP=
MRSIRSFANDDRHVMVKHSTIYPSPEELEAVQNMVSTVECALKHVSDWLDETNKGTKTEGETEVKKDEAGENYSKDQGGRTLCGVMRIGL
VAKGLLIKDDMDLELVLMCKDKPTETLLNTVKDNLPIQIQKLTEEKYQVEQCVNEASIIIRNTKEPTLTLKVILTSPLIRDELEKKDGEN
VSMKDPPDLLDRQKCLNALASLRHAKWFQARANGLKSCVIVLRILRDLCNRVPTWAPLKGWPLELICEKSIGTCNRPLGAGEALRRVMEC
LASGILLPGGPGLHDPCERDPTDALSYMTIQQKEDITHSAQHALRLSAFGQIYKVLEMDPLPSSKPFQKYSWSVTDKEGAGSSALKRPFE
DGLGDDKDPNKKMKRNLRKILDSKAIDLMNALMRLNQIRPGLQYKLLSQSGPVHAPVFTMSVDVDGTTYEASGPSKKTAKLHVAVKVLQA
MGYPTGFDADIECMSSDEKSDNESKNETVSSNSSNNTGNSTTETSSTLEVRTQGPILTASGKNPVMELNEKRRGLKYELISETGGSHDKR
FVMEVEVDGQKFRGAGPNKKVAKASAALAALEKLFSGPNAANNKKKKIIPQAKGVVNTAVSAAVQAVRGRGRGTLTRGAFVGATAAPGYI

--------------------------------------------------------------
>87699_87699_3_STRBP-PRKACB_STRBP_chr9_125890493_ENST00000447404_PRKACB_chr1_84700863_ENST00000370689_length(transcript)=5566nt_BP=2247nt
CCGGAGCCGCGAGCGCCACCAGGGCAGCAGCCGCCGCAGCCGCCGCCGCTGGGCAGAGGAGCCGGAGACGCGAGCGGGCGAGGTGGCGGC
GGCGGCGGAGCGGGAGCGGGTACCGGGCGCGGGCAGAGCGCGGCGGCGCGGGTGTGTTCCAGAGAACAAGCCTTCAGACATTTGCTATAT
TGACGCTGAGCTGTCAGGGGACTCAGGCTTATGAGGAGGTATTGTTACACAAAACAGTGTCTAGTGAAGACGACAAGAAAGAGGGGAAAG
GATCGGAAAAAGAAGCTAAAATACTATAGAAAACCATGAGATCTATTCGATCTTTTGCTAATGATGATCGCCATGTTATGGTGAAACATT
CAACAATCTATCCATCTCCGGAGGAACTTGAAGCTGTTCAGAATATGGTATCTACTGTTGAATGTGCTCTTAAACATGTCTCAGATTGGT
TGGATGAAACAAATAAAGGCACAAAAACAGAGGGTGAGACAGAAGTGAAGAAAGATGAGGCCGGAGAAAACTATTCCAAGGATCAAGGTG
GTCGGACATTGTGTGGTGTAATGAGGATTGGCCTGGTTGCAAAAGGCTTGCTGATTAAAGATGATATGGACTTGGAGCTGGTTTTAATGT
GCAAAGACAAACCCACAGAGACCCTGTTAAATACAGTCAAAGATAATCTTCCTATTCAGATTCAGAAACTCACAGAAGAGAAATATCAAG
TGGAACAATGTGTAAATGAGGCATCTATTATAATTCGGAATACAAAAGAGCCCACGCTAACTTTGAAGGTGATACTTACCTCACCTCTAA
TTAGGGACGAATTGGAGAAGAAGGATGGAGAAAATGTTTCGATGAAAGATCCTCCGGACTTATTGGACAGGCAGAAATGCCTGAACGCCT
TGGCGTCTCTTCGACATGCCAAATGGTTTCAGGCAAGGGCAAATGGATTAAAATCATGTGTAATTGTCCTCCGCATTCTGCGTGATTTGT
GCAACAGAGTCCCCACATGGGCACCATTGAAAGGATGGCCACTAGAACTTATATGTGAAAAGTCTATAGGTACTTGTAATAGACCTTTGG
GCGCTGGGGAGGCCTTGAGACGAGTAATGGAGTGTTTGGCATCTGGAATACTACTTCCTGGGGGTCCTGGTCTTCATGATCCTTGTGAGC
GAGACCCAACAGATGCTCTGAGCTATATGACCATCCAGCAAAAAGAAGATATTACCCACAGTGCACAGCATGCACTCAGACTATCAGCCT
TTGGCCAGATTTACAAAGTGCTGGAGATGGACCCCCTTCCATCTAGTAAGCCTTTTCAGAAGTATTCCTGGTCAGTTACTGATAAAGAAG
GTGCTGGGTCTTCAGCTCTAAAGAGGCCATTTGAAGATGGATTAGGGGATGATAAAGACCCCAACAAGAAGATGAAACGAAACTTAAGGA
AAATTCTGGATAGTAAAGCAATAGACCTTATGAATGCACTAATGAGGCTAAATCAGATCAGGCCTGGGCTTCAGTATAAGCTCCTATCTC
AGTCTGGCCCCGTTCATGCCCCAGTCTTCACAATGTCTGTAGATGTGGATGGCACAACATATGAAGCCTCAGGACCATCCAAGAAAACAG
CAAAACTTCACGTAGCGGTGAAGGTATTGCAGGCAATGGGATATCCAACAGGCTTTGATGCAGATATTGAATGTATGAGTTCCGATGAAA
AATCAGATAATGAAAGTAAAAATGAAACAGTGTCTTCAAACTCAAGCAATAATACTGGAAATTCTACAACTGAAACCTCCAGTACCTTAG
AGGTAAGAACTCAGGGCCCTATCCTCACAGCAAGTGGCAAAAACCCTGTAATGGAGCTCAATGAAAAAAGAAGAGGTCTCAAGTATGAAC
TCATCTCAGAGACTGGTGGAAGCCATGACAAGCGCTTTGTAATGGAGGTAGAAGTAGATGGACAGAAATTCAGAGGCGCAGGTCCAAATA
AGAAAGTGGCAAAGGCGAGTGCAGCTTTAGCTGCCTTGGAGAAACTGTTTTCTGGACCCAATGCGGCAAATAATAAGAAAAAGAAGATTA
TCCCTCAGGCAAAGGGCGTTGTGAATACAGCTGTGTCTGCAGCAGTCCAAGCTGTTCGGGGCAGAGGAAGAGGAACTCTAACAAGGGGAG
CTTTTGTTGGGGCGACAGCTGCTCCTGGCTACATAGCTCCAGGCTATGGAACACCATATGGTTACAGCACAGCTGCCCCTGCCTATGGTT
GAAGCTCCATTCATACCAAAGTTTAGAGGCTCTGGAGATACCAGCAACTTTGATGACTATGAAGAAGAAGATATCCGTGTCTCTATAACA
GAAAAATGTGCAAAAGAATTTGGTGAATTTTAAAGAGGAACAAGATGACATCTGAGCTCACACTCAGTGTTTGCACTCTGTTGAGAGATA
AGGTAGAGCTGAGACCGTCCTTGTTGAAGCAGTTACCTAGTTCCTTCATTCCAACGACTGAGTGAGGTCTTTATTGCCATCATCCCGTGT
GCGCACTCTGCATCCACCTATGTAACAAGGCACCGCTAAGCAAGCATTGTCTGTGCCATAACACAGTACTAGACCACTTTCTTACTTCTC
TTTGGGTTGTCTTTCTCCTCTCCTATATCCATTTCTTCCTTTTCCAATTTCATTGGTTTTCTCTAAACAGTGCTCCATTTTATTTTGTTG
GTGTTTCAGATGGGCAGTGTTATGGCTACGTGATATTTGAAGGGAAGGATAAGTGTTGCTTTCAGTAGTTATTGCCAATATTGTTGTTGG
TCAATGGCTTGAAGATAAACTTTCTAATAATTATTATTTCTTTGAGTAGCTCAGACTTGGTTTTGCCAAAACTCTTGGTAATTTTTGAAG
ATAGACTGTCTTATCACCAAGGAAATTTATACAAATTAAGACTAACTTTCTTGGAATTCACTATTCTGGCAATAAATTTTGGTAGACTAA
TACAGTACAGCTAGACCCAGAAATTTGGAAGGCTGTAGATCAGAGGTTCTAGTTCCCTTTCCCTCCTTTTATATCCTCCTCTCCTTGAGT
AATGAAGTGACCAGCCTGTGTAGTGTGACAAACGTGTCTCATTCAGCAGGAAAAACTAATGATATGGATCATCACCCAGATTCTCTCACT
TGGTACCAGCATTTCTGTAGGTATTAGAGAAGAGTTCTAAGTTTTCTAAACCTTAACTGTTCCTTAAGGATTTTAGCCAGTATTTTAATA
GAACATGATTAATGAAAGTGACAAATTTTAAATTTTCTCTAATAGTCCTCATCATAAACTTTTTAAAGGAAAATAAGCAAACTAAAAAGA
ACATTGGTTTAGATAAATACTTATACTTTGCAAAGTCAAAAATGGCTTGATTTTTGGAAACAATATAGAGGTATTCATATTTAAATGAGG
GTTTACATTTGTTTTGTTTTGTAACCGTTAAAAAGAAGTTGTTTCCAGCTAATTATTGTGGTGTACTATATTTGTGAGCCTAGGGTAGGG
GCACTGCTGCAACTTCTGCTTTCATCCCATGCCTCATCAATGAGGAAAGGGAACAAAGTGTATAAAACTGCCACAATTGTATTTTAATTT
TGAGGTATGATATTTTCAGATATTTCATAATTTCTAACCTCTGTTCTCTCAGTAAACAGAATGTCTGATCGATCATGCAGATACAATGTT
GGTATTTGAGAGGTTAGTTTTTTTCCTACACTTTTTTTTGCCAACTGACTTAACAACATTGCTGTCAGGTGGAAATTTCAAGCACTTTTG
CACATTTAGTTCAGTGTTTGTTGAGAATCCATGGCTTAACCCACTTGTTTTGCTATTTTTTTCTTTGCTTTTAATTTTCCCCATCTGATT
TTATCTCTGCGTTTCAGTGACCTACCTTAAAACAACACACGAGAAGAGTTAAACTGGGTTCATTTTAATGATCAATTTACCTGCATATAA
AATTTATTTTTAATCAAGCTGATCTTAATGTATATAATCATTCTATTTGCTTTATTATCGGTGCAGGTAGGTCATTAACACCACTTCTTT
TCATCTGTACCACACCCTGGTGAAACCTTTGAAGACATAAAAAAAACCTGTCTGAGATGTTCTTTCTACCAATCTATATGTCTTTCGGTT
ATCAAGTGTTTCTGCATGGTAATGTCATGTAAATGCTGATATTGATTTCACTGGTCCATCTATATTTAAAACGTGCAAGAAAAAAATAAA
ATACTCTGCTCTAGCAAGTTTTGTGTAACAAAGGCATATCGTCATGTTAATAAATTTAAAACATCATTCGTATAAAATATTTTAATTTTC
TTGTATTTCATTTAGACCCAAGAACATGCTGACCAATGTGTTCTATATGTAAACTACAAATTCTATGGTAGCTTTGTTGTATATTATTGT
AAAATTATTTTAATAAGTCATGGGGATGACAATTTGATTATTACAATTTAGTTTTCAGTAATCAAAAAGATTTCTATGAATTCTAAAAAA
TATTTTTTTCTATGAAATTACTAGTGCCCAGCTGTAGAATCTACCTTAGGTAGATGATCCCTAGACATACGTTGGTTTTGAGGGCTATTC
AGCCATTCCATTTTACTCTCTATTTAAAGGCCGTGAGCAAGCTTGTCATGAGCAAATATGTCAAGGGAGTCAATTTCTGACCAATCAAGT
ACACTAAATTAGAATATTTTTAAAGTATGTAACATTCCCAGTTTCAGCCACAATTTAGCCAAGAATAAGATAAAAACTTGAATAAGAAGT
AAGTAGCATAAATCAGTATTTAACCTAAAATTACATATTTGAAACAGAAGATATTATGTTATGCTCAGTAAATAATTAAGAGATGGCATT
GTGTAAGAAGGAGCCCTAGACTGAAAGTCAAGACATCTGAATTTCAGGCTGGAAAACTATCAGTATGATCTCAGCCTCAGTTCTCTTGTC
TGTAAAATGGAAGAACTGGATTAGGCAGTTTGTAAGATTCCTCCTAACTTTCACAGTCGATGACAAGATTGTCTTTTTATCTGATATTTT
GAAGGGTATATTGCTTTGAAGTAAGTCTCAATAAGGCAATATATTTTAGGGCATCTTTCTTCTTATCTCTGACAGTGTTCTTAAAATTAT
TTGAATATCATAAGAGCCTTGGTGTCTGTCCTAATTCCTTTCTCACTCACCGATGCTGAATACCCAGTTGAATCAAACTGTCAACCTACC
AAAAACGATATTGTGGCTTATGGGTATTGCTGTCTCATTCTTGGTATATTCTTGTGTTAACTGCCCATTGGCCTGAAAATACTCATTGTA
AGCCTGAAAAAAAAAATCTTTCCCACTGTTTTTTCTGCTTGTTGTAAGAATCAAATGAAATAATGTATGTGAAAGCACCTTGTAAACTGT
AACCTATCAATGTAAAATGTTAAGGTGTGTTGTTATTTCATTAATTACTTCTTTGTTTAGAATGGAATTTCCTATGCACTACTGTAGCTA

>87699_87699_3_STRBP-PRKACB_STRBP_chr9_125890493_ENST00000447404_PRKACB_chr1_84700863_ENST00000370689_length(amino acids)=648AA_BP=
MRSIRSFANDDRHVMVKHSTIYPSPEELEAVQNMVSTVECALKHVSDWLDETNKGTKTEGETEVKKDEAGENYSKDQGGRTLCGVMRIGL
VAKGLLIKDDMDLELVLMCKDKPTETLLNTVKDNLPIQIQKLTEEKYQVEQCVNEASIIIRNTKEPTLTLKVILTSPLIRDELEKKDGEN
VSMKDPPDLLDRQKCLNALASLRHAKWFQARANGLKSCVIVLRILRDLCNRVPTWAPLKGWPLELICEKSIGTCNRPLGAGEALRRVMEC
LASGILLPGGPGLHDPCERDPTDALSYMTIQQKEDITHSAQHALRLSAFGQIYKVLEMDPLPSSKPFQKYSWSVTDKEGAGSSALKRPFE
DGLGDDKDPNKKMKRNLRKILDSKAIDLMNALMRLNQIRPGLQYKLLSQSGPVHAPVFTMSVDVDGTTYEASGPSKKTAKLHVAVKVLQA
MGYPTGFDADIECMSSDEKSDNESKNETVSSNSSNNTGNSTTETSSTLEVRTQGPILTASGKNPVMELNEKRRGLKYELISETGGSHDKR
FVMEVEVDGQKFRGAGPNKKVAKASAALAALEKLFSGPNAANNKKKKIIPQAKGVVNTAVSAAVQAVRGRGRGTLTRGAFVGATAAPGYI

--------------------------------------------------------------
>87699_87699_4_STRBP-PRKACB_STRBP_chr9_125890493_ENST00000447404_PRKACB_chr1_84700863_ENST00000394838_length(transcript)=5557nt_BP=2247nt
CCGGAGCCGCGAGCGCCACCAGGGCAGCAGCCGCCGCAGCCGCCGCCGCTGGGCAGAGGAGCCGGAGACGCGAGCGGGCGAGGTGGCGGC
GGCGGCGGAGCGGGAGCGGGTACCGGGCGCGGGCAGAGCGCGGCGGCGCGGGTGTGTTCCAGAGAACAAGCCTTCAGACATTTGCTATAT
TGACGCTGAGCTGTCAGGGGACTCAGGCTTATGAGGAGGTATTGTTACACAAAACAGTGTCTAGTGAAGACGACAAGAAAGAGGGGAAAG
GATCGGAAAAAGAAGCTAAAATACTATAGAAAACCATGAGATCTATTCGATCTTTTGCTAATGATGATCGCCATGTTATGGTGAAACATT
CAACAATCTATCCATCTCCGGAGGAACTTGAAGCTGTTCAGAATATGGTATCTACTGTTGAATGTGCTCTTAAACATGTCTCAGATTGGT
TGGATGAAACAAATAAAGGCACAAAAACAGAGGGTGAGACAGAAGTGAAGAAAGATGAGGCCGGAGAAAACTATTCCAAGGATCAAGGTG
GTCGGACATTGTGTGGTGTAATGAGGATTGGCCTGGTTGCAAAAGGCTTGCTGATTAAAGATGATATGGACTTGGAGCTGGTTTTAATGT
GCAAAGACAAACCCACAGAGACCCTGTTAAATACAGTCAAAGATAATCTTCCTATTCAGATTCAGAAACTCACAGAAGAGAAATATCAAG
TGGAACAATGTGTAAATGAGGCATCTATTATAATTCGGAATACAAAAGAGCCCACGCTAACTTTGAAGGTGATACTTACCTCACCTCTAA
TTAGGGACGAATTGGAGAAGAAGGATGGAGAAAATGTTTCGATGAAAGATCCTCCGGACTTATTGGACAGGCAGAAATGCCTGAACGCCT
TGGCGTCTCTTCGACATGCCAAATGGTTTCAGGCAAGGGCAAATGGATTAAAATCATGTGTAATTGTCCTCCGCATTCTGCGTGATTTGT
GCAACAGAGTCCCCACATGGGCACCATTGAAAGGATGGCCACTAGAACTTATATGTGAAAAGTCTATAGGTACTTGTAATAGACCTTTGG
GCGCTGGGGAGGCCTTGAGACGAGTAATGGAGTGTTTGGCATCTGGAATACTACTTCCTGGGGGTCCTGGTCTTCATGATCCTTGTGAGC
GAGACCCAACAGATGCTCTGAGCTATATGACCATCCAGCAAAAAGAAGATATTACCCACAGTGCACAGCATGCACTCAGACTATCAGCCT
TTGGCCAGATTTACAAAGTGCTGGAGATGGACCCCCTTCCATCTAGTAAGCCTTTTCAGAAGTATTCCTGGTCAGTTACTGATAAAGAAG
GTGCTGGGTCTTCAGCTCTAAAGAGGCCATTTGAAGATGGATTAGGGGATGATAAAGACCCCAACAAGAAGATGAAACGAAACTTAAGGA
AAATTCTGGATAGTAAAGCAATAGACCTTATGAATGCACTAATGAGGCTAAATCAGATCAGGCCTGGGCTTCAGTATAAGCTCCTATCTC
AGTCTGGCCCCGTTCATGCCCCAGTCTTCACAATGTCTGTAGATGTGGATGGCACAACATATGAAGCCTCAGGACCATCCAAGAAAACAG
CAAAACTTCACGTAGCGGTGAAGGTATTGCAGGCAATGGGATATCCAACAGGCTTTGATGCAGATATTGAATGTATGAGTTCCGATGAAA
AATCAGATAATGAAAGTAAAAATGAAACAGTGTCTTCAAACTCAAGCAATAATACTGGAAATTCTACAACTGAAACCTCCAGTACCTTAG
AGGTAAGAACTCAGGGCCCTATCCTCACAGCAAGTGGCAAAAACCCTGTAATGGAGCTCAATGAAAAAAGAAGAGGTCTCAAGTATGAAC
TCATCTCAGAGACTGGTGGAAGCCATGACAAGCGCTTTGTAATGGAGGTAGAAGTAGATGGACAGAAATTCAGAGGCGCAGGTCCAAATA
AGAAAGTGGCAAAGGCGAGTGCAGCTTTAGCTGCCTTGGAGAAACTGTTTTCTGGACCCAATGCGGCAAATAATAAGAAAAAGAAGATTA
TCCCTCAGGCAAAGGGCGTTGTGAATACAGCTGTGTCTGCAGCAGTCCAAGCTGTTCGGGGCAGAGGAAGAGGAACTCTAACAAGGGGAG
CTTTTGTTGGGGCGACAGCTGCTCCTGGCTACATAGCTCCAGGCTATGGAACACCATATGGTTACAGCACAGCTGCCCCTGCCTATGGTT
GAAGCTCCATTCATACCAAAGTTTAGAGGCTCTGGAGATACCAGCAACTTTGATGACTATGAAGAAGAAGATATCCGTGTCTCTATAACA
GAAAAATGTGCAAAAGAATTTGGTGAATTTTAAAGAGGAACAAGATGACATCTGAGCTCACACTCAGTGTTTGCACTCTGTTGAGAGATA
AGGTAGAGCTGAGACCGTCCTTGTTGAAGCAGTTACCTAGTTCCTTCATTCCAACGACTGAGTGAGGTCTTTATTGCCATCATCCCGTGT
GCGCACTCTGCATCCACCTATGTAACAAGGCACCGCTAAGCAAGCATTGTCTGTGCCATAACACAGTACTAGACCACTTTCTTACTTCTC
TTTGGGTTGTCTTTCTCCTCTCCTATATCCATTTCTTCCTTTTCCAATTTCATTGGTTTTCTCTAAACAGTGCTCCATTTTATTTTGTTG
GTGTTTCAGATGGGCAGTGTTATGGCTACGTGATATTTGAAGGGAAGGATAAGTGTTGCTTTCAGTAGTTATTGCCAATATTGTTGTTGG
TCAATGGCTTGAAGATAAACTTTCTAATAATTATTATTTCTTTGAGTAGCTCAGACTTGGTTTTGCCAAAACTCTTGGTAATTTTTGAAG
ATAGACTGTCTTATCACCAAGGAAATTTATACAAATTAAGACTAACTTTCTTGGAATTCACTATTCTGGCAATAAATTTTGGTAGACTAA
TACAGTACAGCTAGACCCAGAAATTTGGAAGGCTGTAGATCAGAGGTTCTAGTTCCCTTTCCCTCCTTTTATATCCTCCTCTCCTTGAGT
AATGAAGTGACCAGCCTGTGTAGTGTGACAAACGTGTCTCATTCAGCAGGAAAAACTAATGATATGGATCATCACCCAGATTCTCTCACT
TGGTACCAGCATTTCTGTAGGTATTAGAGAAGAGTTCTAAGTTTTCTAAACCTTAACTGTTCCTTAAGGATTTTAGCCAGTATTTTAATA
GAACATGATTAATGAAAGTGACAAATTTTAAATTTTCTCTAATAGTCCTCATCATAAACTTTTTAAAGGAAAATAAGCAAACTAAAAAGA
ACATTGGTTTAGATAAATACTTATACTTTGCAAAGTCAAAAATGGCTTGATTTTTGGAAACAATATAGAGGTATTCATATTTAAATGAGG
GTTTACATTTGTTTTGTTTTGTAACCGTTAAAAAGAAGTTGTTTCCAGCTAATTATTGTGGTGTACTATATTTGTGAGCCTAGGGTAGGG
GCACTGCTGCAACTTCTGCTTTCATCCCATGCCTCATCAATGAGGAAAGGGAACAAAGTGTATAAAACTGCCACAATTGTATTTTAATTT
TGAGGTATGATATTTTCAGATATTTCATAATTTCTAACCTCTGTTCTCTCAGTAAACAGAATGTCTGATCGATCATGCAGATACAATGTT
GGTATTTGAGAGGTTAGTTTTTTTCCTACACTTTTTTTTGCCAACTGACTTAACAACATTGCTGTCAGGTGGAAATTTCAAGCACTTTTG
CACATTTAGTTCAGTGTTTGTTGAGAATCCATGGCTTAACCCACTTGTTTTGCTATTTTTTTCTTTGCTTTTAATTTTCCCCATCTGATT
TTATCTCTGCGTTTCAGTGACCTACCTTAAAACAACACACGAGAAGAGTTAAACTGGGTTCATTTTAATGATCAATTTACCTGCATATAA
AATTTATTTTTAATCAAGCTGATCTTAATGTATATAATCATTCTATTTGCTTTATTATCGGTGCAGGTAGGTCATTAACACCACTTCTTT
TCATCTGTACCACACCCTGGTGAAACCTTTGAAGACATAAAAAAAACCTGTCTGAGATGTTCTTTCTACCAATCTATATGTCTTTCGGTT
ATCAAGTGTTTCTGCATGGTAATGTCATGTAAATGCTGATATTGATTTCACTGGTCCATCTATATTTAAAACGTGCAAGAAAAAAATAAA
ATACTCTGCTCTAGCAAGTTTTGTGTAACAAAGGCATATCGTCATGTTAATAAATTTAAAACATCATTCGTATAAAATATTTTAATTTTC
TTGTATTTCATTTAGACCCAAGAACATGCTGACCAATGTGTTCTATATGTAAACTACAAATTCTATGGTAGCTTTGTTGTATATTATTGT
AAAATTATTTTAATAAGTCATGGGGATGACAATTTGATTATTACAATTTAGTTTTCAGTAATCAAAAAGATTTCTATGAATTCTAAAAAA
TATTTTTTTCTATGAAATTACTAGTGCCCAGCTGTAGAATCTACCTTAGGTAGATGATCCCTAGACATACGTTGGTTTTGAGGGCTATTC
AGCCATTCCATTTTACTCTCTATTTAAAGGCCGTGAGCAAGCTTGTCATGAGCAAATATGTCAAGGGAGTCAATTTCTGACCAATCAAGT
ACACTAAATTAGAATATTTTTAAAGTATGTAACATTCCCAGTTTCAGCCACAATTTAGCCAAGAATAAGATAAAAACTTGAATAAGAAGT
AAGTAGCATAAATCAGTATTTAACCTAAAATTACATATTTGAAACAGAAGATATTATGTTATGCTCAGTAAATAATTAAGAGATGGCATT
GTGTAAGAAGGAGCCCTAGACTGAAAGTCAAGACATCTGAATTTCAGGCTGGAAAACTATCAGTATGATCTCAGCCTCAGTTCTCTTGTC
TGTAAAATGGAAGAACTGGATTAGGCAGTTTGTAAGATTCCTCCTAACTTTCACAGTCGATGACAAGATTGTCTTTTTATCTGATATTTT
GAAGGGTATATTGCTTTGAAGTAAGTCTCAATAAGGCAATATATTTTAGGGCATCTTTCTTCTTATCTCTGACAGTGTTCTTAAAATTAT
TTGAATATCATAAGAGCCTTGGTGTCTGTCCTAATTCCTTTCTCACTCACCGATGCTGAATACCCAGTTGAATCAAACTGTCAACCTACC
AAAAACGATATTGTGGCTTATGGGTATTGCTGTCTCATTCTTGGTATATTCTTGTGTTAACTGCCCATTGGCCTGAAAATACTCATTGTA
AGCCTGAAAAAAAAAATCTTTCCCACTGTTTTTTCTGCTTGTTGTAAGAATCAAATGAAATAATGTATGTGAAAGCACCTTGTAAACTGT
AACCTATCAATGTAAAATGTTAAGGTGTGTTGTTATTTCATTAATTACTTCTTTGTTTAGAATGGAATTTCCTATGCACTACTGTAGCTA

>87699_87699_4_STRBP-PRKACB_STRBP_chr9_125890493_ENST00000447404_PRKACB_chr1_84700863_ENST00000394838_length(amino acids)=648AA_BP=
MRSIRSFANDDRHVMVKHSTIYPSPEELEAVQNMVSTVECALKHVSDWLDETNKGTKTEGETEVKKDEAGENYSKDQGGRTLCGVMRIGL
VAKGLLIKDDMDLELVLMCKDKPTETLLNTVKDNLPIQIQKLTEEKYQVEQCVNEASIIIRNTKEPTLTLKVILTSPLIRDELEKKDGEN
VSMKDPPDLLDRQKCLNALASLRHAKWFQARANGLKSCVIVLRILRDLCNRVPTWAPLKGWPLELICEKSIGTCNRPLGAGEALRRVMEC
LASGILLPGGPGLHDPCERDPTDALSYMTIQQKEDITHSAQHALRLSAFGQIYKVLEMDPLPSSKPFQKYSWSVTDKEGAGSSALKRPFE
DGLGDDKDPNKKMKRNLRKILDSKAIDLMNALMRLNQIRPGLQYKLLSQSGPVHAPVFTMSVDVDGTTYEASGPSKKTAKLHVAVKVLQA
MGYPTGFDADIECMSSDEKSDNESKNETVSSNSSNNTGNSTTETSSTLEVRTQGPILTASGKNPVMELNEKRRGLKYELISETGGSHDKR
FVMEVEVDGQKFRGAGPNKKVAKASAALAALEKLFSGPNAANNKKKKIIPQAKGVVNTAVSAAVQAVRGRGRGTLTRGAFVGATAAPGYI

--------------------------------------------------------------
>87699_87699_5_STRBP-PRKACB_STRBP_chr9_125890493_ENST00000447404_PRKACB_chr1_84700863_ENST00000394839_length(transcript)=5566nt_BP=2247nt
CCGGAGCCGCGAGCGCCACCAGGGCAGCAGCCGCCGCAGCCGCCGCCGCTGGGCAGAGGAGCCGGAGACGCGAGCGGGCGAGGTGGCGGC
GGCGGCGGAGCGGGAGCGGGTACCGGGCGCGGGCAGAGCGCGGCGGCGCGGGTGTGTTCCAGAGAACAAGCCTTCAGACATTTGCTATAT
TGACGCTGAGCTGTCAGGGGACTCAGGCTTATGAGGAGGTATTGTTACACAAAACAGTGTCTAGTGAAGACGACAAGAAAGAGGGGAAAG
GATCGGAAAAAGAAGCTAAAATACTATAGAAAACCATGAGATCTATTCGATCTTTTGCTAATGATGATCGCCATGTTATGGTGAAACATT
CAACAATCTATCCATCTCCGGAGGAACTTGAAGCTGTTCAGAATATGGTATCTACTGTTGAATGTGCTCTTAAACATGTCTCAGATTGGT
TGGATGAAACAAATAAAGGCACAAAAACAGAGGGTGAGACAGAAGTGAAGAAAGATGAGGCCGGAGAAAACTATTCCAAGGATCAAGGTG
GTCGGACATTGTGTGGTGTAATGAGGATTGGCCTGGTTGCAAAAGGCTTGCTGATTAAAGATGATATGGACTTGGAGCTGGTTTTAATGT
GCAAAGACAAACCCACAGAGACCCTGTTAAATACAGTCAAAGATAATCTTCCTATTCAGATTCAGAAACTCACAGAAGAGAAATATCAAG
TGGAACAATGTGTAAATGAGGCATCTATTATAATTCGGAATACAAAAGAGCCCACGCTAACTTTGAAGGTGATACTTACCTCACCTCTAA
TTAGGGACGAATTGGAGAAGAAGGATGGAGAAAATGTTTCGATGAAAGATCCTCCGGACTTATTGGACAGGCAGAAATGCCTGAACGCCT
TGGCGTCTCTTCGACATGCCAAATGGTTTCAGGCAAGGGCAAATGGATTAAAATCATGTGTAATTGTCCTCCGCATTCTGCGTGATTTGT
GCAACAGAGTCCCCACATGGGCACCATTGAAAGGATGGCCACTAGAACTTATATGTGAAAAGTCTATAGGTACTTGTAATAGACCTTTGG
GCGCTGGGGAGGCCTTGAGACGAGTAATGGAGTGTTTGGCATCTGGAATACTACTTCCTGGGGGTCCTGGTCTTCATGATCCTTGTGAGC
GAGACCCAACAGATGCTCTGAGCTATATGACCATCCAGCAAAAAGAAGATATTACCCACAGTGCACAGCATGCACTCAGACTATCAGCCT
TTGGCCAGATTTACAAAGTGCTGGAGATGGACCCCCTTCCATCTAGTAAGCCTTTTCAGAAGTATTCCTGGTCAGTTACTGATAAAGAAG
GTGCTGGGTCTTCAGCTCTAAAGAGGCCATTTGAAGATGGATTAGGGGATGATAAAGACCCCAACAAGAAGATGAAACGAAACTTAAGGA
AAATTCTGGATAGTAAAGCAATAGACCTTATGAATGCACTAATGAGGCTAAATCAGATCAGGCCTGGGCTTCAGTATAAGCTCCTATCTC
AGTCTGGCCCCGTTCATGCCCCAGTCTTCACAATGTCTGTAGATGTGGATGGCACAACATATGAAGCCTCAGGACCATCCAAGAAAACAG
CAAAACTTCACGTAGCGGTGAAGGTATTGCAGGCAATGGGATATCCAACAGGCTTTGATGCAGATATTGAATGTATGAGTTCCGATGAAA
AATCAGATAATGAAAGTAAAAATGAAACAGTGTCTTCAAACTCAAGCAATAATACTGGAAATTCTACAACTGAAACCTCCAGTACCTTAG
AGGTAAGAACTCAGGGCCCTATCCTCACAGCAAGTGGCAAAAACCCTGTAATGGAGCTCAATGAAAAAAGAAGAGGTCTCAAGTATGAAC
TCATCTCAGAGACTGGTGGAAGCCATGACAAGCGCTTTGTAATGGAGGTAGAAGTAGATGGACAGAAATTCAGAGGCGCAGGTCCAAATA
AGAAAGTGGCAAAGGCGAGTGCAGCTTTAGCTGCCTTGGAGAAACTGTTTTCTGGACCCAATGCGGCAAATAATAAGAAAAAGAAGATTA
TCCCTCAGGCAAAGGGCGTTGTGAATACAGCTGTGTCTGCAGCAGTCCAAGCTGTTCGGGGCAGAGGAAGAGGAACTCTAACAAGGGGAG
CTTTTGTTGGGGCGACAGCTGCTCCTGGCTACATAGCTCCAGGCTATGGAACACCATATGGTTACAGCACAGCTGCCCCTGCCTATGGTT
GAAGCTCCATTCATACCAAAGTTTAGAGGCTCTGGAGATACCAGCAACTTTGATGACTATGAAGAAGAAGATATCCGTGTCTCTATAACA
GAAAAATGTGCAAAAGAATTTGGTGAATTTTAAAGAGGAACAAGATGACATCTGAGCTCACACTCAGTGTTTGCACTCTGTTGAGAGATA
AGGTAGAGCTGAGACCGTCCTTGTTGAAGCAGTTACCTAGTTCCTTCATTCCAACGACTGAGTGAGGTCTTTATTGCCATCATCCCGTGT
GCGCACTCTGCATCCACCTATGTAACAAGGCACCGCTAAGCAAGCATTGTCTGTGCCATAACACAGTACTAGACCACTTTCTTACTTCTC
TTTGGGTTGTCTTTCTCCTCTCCTATATCCATTTCTTCCTTTTCCAATTTCATTGGTTTTCTCTAAACAGTGCTCCATTTTATTTTGTTG
GTGTTTCAGATGGGCAGTGTTATGGCTACGTGATATTTGAAGGGAAGGATAAGTGTTGCTTTCAGTAGTTATTGCCAATATTGTTGTTGG
TCAATGGCTTGAAGATAAACTTTCTAATAATTATTATTTCTTTGAGTAGCTCAGACTTGGTTTTGCCAAAACTCTTGGTAATTTTTGAAG
ATAGACTGTCTTATCACCAAGGAAATTTATACAAATTAAGACTAACTTTCTTGGAATTCACTATTCTGGCAATAAATTTTGGTAGACTAA
TACAGTACAGCTAGACCCAGAAATTTGGAAGGCTGTAGATCAGAGGTTCTAGTTCCCTTTCCCTCCTTTTATATCCTCCTCTCCTTGAGT
AATGAAGTGACCAGCCTGTGTAGTGTGACAAACGTGTCTCATTCAGCAGGAAAAACTAATGATATGGATCATCACCCAGATTCTCTCACT
TGGTACCAGCATTTCTGTAGGTATTAGAGAAGAGTTCTAAGTTTTCTAAACCTTAACTGTTCCTTAAGGATTTTAGCCAGTATTTTAATA
GAACATGATTAATGAAAGTGACAAATTTTAAATTTTCTCTAATAGTCCTCATCATAAACTTTTTAAAGGAAAATAAGCAAACTAAAAAGA
ACATTGGTTTAGATAAATACTTATACTTTGCAAAGTCAAAAATGGCTTGATTTTTGGAAACAATATAGAGGTATTCATATTTAAATGAGG
GTTTACATTTGTTTTGTTTTGTAACCGTTAAAAAGAAGTTGTTTCCAGCTAATTATTGTGGTGTACTATATTTGTGAGCCTAGGGTAGGG
GCACTGCTGCAACTTCTGCTTTCATCCCATGCCTCATCAATGAGGAAAGGGAACAAAGTGTATAAAACTGCCACAATTGTATTTTAATTT
TGAGGTATGATATTTTCAGATATTTCATAATTTCTAACCTCTGTTCTCTCAGTAAACAGAATGTCTGATCGATCATGCAGATACAATGTT
GGTATTTGAGAGGTTAGTTTTTTTCCTACACTTTTTTTTGCCAACTGACTTAACAACATTGCTGTCAGGTGGAAATTTCAAGCACTTTTG
CACATTTAGTTCAGTGTTTGTTGAGAATCCATGGCTTAACCCACTTGTTTTGCTATTTTTTTCTTTGCTTTTAATTTTCCCCATCTGATT
TTATCTCTGCGTTTCAGTGACCTACCTTAAAACAACACACGAGAAGAGTTAAACTGGGTTCATTTTAATGATCAATTTACCTGCATATAA
AATTTATTTTTAATCAAGCTGATCTTAATGTATATAATCATTCTATTTGCTTTATTATCGGTGCAGGTAGGTCATTAACACCACTTCTTT
TCATCTGTACCACACCCTGGTGAAACCTTTGAAGACATAAAAAAAACCTGTCTGAGATGTTCTTTCTACCAATCTATATGTCTTTCGGTT
ATCAAGTGTTTCTGCATGGTAATGTCATGTAAATGCTGATATTGATTTCACTGGTCCATCTATATTTAAAACGTGCAAGAAAAAAATAAA
ATACTCTGCTCTAGCAAGTTTTGTGTAACAAAGGCATATCGTCATGTTAATAAATTTAAAACATCATTCGTATAAAATATTTTAATTTTC
TTGTATTTCATTTAGACCCAAGAACATGCTGACCAATGTGTTCTATATGTAAACTACAAATTCTATGGTAGCTTTGTTGTATATTATTGT
AAAATTATTTTAATAAGTCATGGGGATGACAATTTGATTATTACAATTTAGTTTTCAGTAATCAAAAAGATTTCTATGAATTCTAAAAAA
TATTTTTTTCTATGAAATTACTAGTGCCCAGCTGTAGAATCTACCTTAGGTAGATGATCCCTAGACATACGTTGGTTTTGAGGGCTATTC
AGCCATTCCATTTTACTCTCTATTTAAAGGCCGTGAGCAAGCTTGTCATGAGCAAATATGTCAAGGGAGTCAATTTCTGACCAATCAAGT
ACACTAAATTAGAATATTTTTAAAGTATGTAACATTCCCAGTTTCAGCCACAATTTAGCCAAGAATAAGATAAAAACTTGAATAAGAAGT
AAGTAGCATAAATCAGTATTTAACCTAAAATTACATATTTGAAACAGAAGATATTATGTTATGCTCAGTAAATAATTAAGAGATGGCATT
GTGTAAGAAGGAGCCCTAGACTGAAAGTCAAGACATCTGAATTTCAGGCTGGAAAACTATCAGTATGATCTCAGCCTCAGTTCTCTTGTC
TGTAAAATGGAAGAACTGGATTAGGCAGTTTGTAAGATTCCTCCTAACTTTCACAGTCGATGACAAGATTGTCTTTTTATCTGATATTTT
GAAGGGTATATTGCTTTGAAGTAAGTCTCAATAAGGCAATATATTTTAGGGCATCTTTCTTCTTATCTCTGACAGTGTTCTTAAAATTAT
TTGAATATCATAAGAGCCTTGGTGTCTGTCCTAATTCCTTTCTCACTCACCGATGCTGAATACCCAGTTGAATCAAACTGTCAACCTACC
AAAAACGATATTGTGGCTTATGGGTATTGCTGTCTCATTCTTGGTATATTCTTGTGTTAACTGCCCATTGGCCTGAAAATACTCATTGTA
AGCCTGAAAAAAAAAATCTTTCCCACTGTTTTTTCTGCTTGTTGTAAGAATCAAATGAAATAATGTATGTGAAAGCACCTTGTAAACTGT
AACCTATCAATGTAAAATGTTAAGGTGTGTTGTTATTTCATTAATTACTTCTTTGTTTAGAATGGAATTTCCTATGCACTACTGTAGCTA

>87699_87699_5_STRBP-PRKACB_STRBP_chr9_125890493_ENST00000447404_PRKACB_chr1_84700863_ENST00000394839_length(amino acids)=648AA_BP=
MRSIRSFANDDRHVMVKHSTIYPSPEELEAVQNMVSTVECALKHVSDWLDETNKGTKTEGETEVKKDEAGENYSKDQGGRTLCGVMRIGL
VAKGLLIKDDMDLELVLMCKDKPTETLLNTVKDNLPIQIQKLTEEKYQVEQCVNEASIIIRNTKEPTLTLKVILTSPLIRDELEKKDGEN
VSMKDPPDLLDRQKCLNALASLRHAKWFQARANGLKSCVIVLRILRDLCNRVPTWAPLKGWPLELICEKSIGTCNRPLGAGEALRRVMEC
LASGILLPGGPGLHDPCERDPTDALSYMTIQQKEDITHSAQHALRLSAFGQIYKVLEMDPLPSSKPFQKYSWSVTDKEGAGSSALKRPFE
DGLGDDKDPNKKMKRNLRKILDSKAIDLMNALMRLNQIRPGLQYKLLSQSGPVHAPVFTMSVDVDGTTYEASGPSKKTAKLHVAVKVLQA
MGYPTGFDADIECMSSDEKSDNESKNETVSSNSSNNTGNSTTETSSTLEVRTQGPILTASGKNPVMELNEKRRGLKYELISETGGSHDKR
FVMEVEVDGQKFRGAGPNKKVAKASAALAALEKLFSGPNAANNKKKKIIPQAKGVVNTAVSAAVQAVRGRGRGTLTRGAFVGATAAPGYI

--------------------------------------------------------------

Top

Fusion Gene PPI Analysis for STRBP-PRKACB


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


Top

Related Drugs for STRBP-PRKACB


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

Top

Related Diseases for STRBP-PRKACB


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource