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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:STRN-HEATR5B (FusionGDB2 ID:87738)

Fusion Gene Summary for STRN-HEATR5B

check button Fusion gene summary
Fusion gene informationFusion gene name: STRN-HEATR5B
Fusion gene ID: 87738
HgeneTgene
Gene symbol

STRN

HEATR5B

Gene ID

6801

54497

Gene namestriatinHEAT repeat containing 5B
SynonymsPPP2R6A|SG2NA|STRN1-
Cytomap

2p22.2

2p22.2

Type of geneprotein-codingprotein-coding
Descriptionstriatinprotein phosphatase 2 regulatory subunit B'''alphastriatin, calmodulin binding proteinHEAT repeat-containing protein 5B
Modification date2020031320200313
UniProtAcc.

Q9P2D3

Ensembl transtripts involved in fusion geneENST00000263918, ENST00000379213, 
ENST00000233099, ENST00000354531, 
Fusion gene scores* DoF score10 X 14 X 10=14004 X 7 X 6=168
# samples 158
** MAII scorelog2(15/1400*10)=-3.22239242133645
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(8/168*10)=-1.0703893278914
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: STRN [Title/Abstract] AND HEATR5B [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointSTRN(37193373)-HEATR5B(37216002), # samples:2
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check buttonFusion gene breakpoints across STRN (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across HEATR5B (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4BRCATCGA-BH-A0BP-01ASTRNchr2

37121041

-HEATR5Bchr2

37293053

-
ChimerDB4CESCTCGA-HM-A6W2-01ASTRNchr2

37193373

-HEATR5Bchr2

37195744

-
ChimerDB4LUSCTCGA-94-8491-01ASTRNchr2

37096697

-HEATR5Bchr2

37208937

-
ChimerDB4SARCTCGA-KD-A5QS-01ASTRNchr2

37193373

-HEATR5Bchr2

37216002

-


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Fusion Gene ORF analysis for STRN-HEATR5B

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000263918ENST00000233099STRNchr2

37193373

-HEATR5Bchr2

37195744

-
5CDS-intronENST00000263918ENST00000354531STRNchr2

37193373

-HEATR5Bchr2

37195744

-
5CDS-intronENST00000379213ENST00000233099STRNchr2

37193373

-HEATR5Bchr2

37195744

-
5CDS-intronENST00000379213ENST00000354531STRNchr2

37193373

-HEATR5Bchr2

37195744

-
In-frameENST00000263918ENST00000233099STRNchr2

37121041

-HEATR5Bchr2

37293053

-
In-frameENST00000263918ENST00000233099STRNchr2

37096697

-HEATR5Bchr2

37208937

-
In-frameENST00000263918ENST00000233099STRNchr2

37193373

-HEATR5Bchr2

37216002

-
In-frameENST00000263918ENST00000354531STRNchr2

37121041

-HEATR5Bchr2

37293053

-
In-frameENST00000263918ENST00000354531STRNchr2

37096697

-HEATR5Bchr2

37208937

-
In-frameENST00000263918ENST00000354531STRNchr2

37193373

-HEATR5Bchr2

37216002

-
In-frameENST00000379213ENST00000233099STRNchr2

37121041

-HEATR5Bchr2

37293053

-
In-frameENST00000379213ENST00000233099STRNchr2

37096697

-HEATR5Bchr2

37208937

-
In-frameENST00000379213ENST00000233099STRNchr2

37193373

-HEATR5Bchr2

37216002

-
In-frameENST00000379213ENST00000354531STRNchr2

37121041

-HEATR5Bchr2

37293053

-
In-frameENST00000379213ENST00000354531STRNchr2

37096697

-HEATR5Bchr2

37208937

-
In-frameENST00000379213ENST00000354531STRNchr2

37193373

-HEATR5Bchr2

37216002

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000263918STRNchr237096697-ENST00000233099HEATR5Bchr237208937-2406150891562517
ENST00000263918STRNchr237096697-ENST00000354531HEATR5Bchr237208937-2293150891562517
ENST00000379213STRNchr237096697-ENST00000233099HEATR5Bchr237208937-2250135201406468
ENST00000379213STRNchr237096697-ENST00000354531HEATR5Bchr237208937-2137135201406468
ENST00000263918STRNchr237121041-ENST00000233099HEATR5Bchr237293053-6572940959781989
ENST00000263918STRNchr237121041-ENST00000354531HEATR5Bchr237293053-6192940957111900
ENST00000379213STRNchr237121041-ENST00000233099HEATR5Bchr237293053-6527895059331977
ENST00000379213STRNchr237121041-ENST00000354531HEATR5Bchr237293053-6147895056661888

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000263918ENST00000233099STRNchr237096697-HEATR5Bchr237208937-0.0004268660.9995732
ENST00000263918ENST00000354531STRNchr237096697-HEATR5Bchr237208937-0.0005459290.9994541
ENST00000379213ENST00000233099STRNchr237096697-HEATR5Bchr237208937-0.0004117540.9995883
ENST00000379213ENST00000354531STRNchr237096697-HEATR5Bchr237208937-0.0005290320.999471
ENST00000263918ENST00000233099STRNchr237121041-HEATR5Bchr237293053-0.0003947530.99960524
ENST00000263918ENST00000354531STRNchr237121041-HEATR5Bchr237293053-0.0008019910.999198
ENST00000379213ENST00000233099STRNchr237121041-HEATR5Bchr237293053-0.000369360.9996306
ENST00000379213ENST00000354531STRNchr237121041-HEATR5Bchr237293053-0.0007516060.9992483

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Fusion Genomic Features for STRN-HEATR5B


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for STRN-HEATR5B


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr2:37193373/chr2:37216002)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
.HEATR5B

Q9P2D3

FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Component of clathrin-coated vesicles (PubMed:15758025). Component of the aftiphilin/p200/gamma-synergin complex, which plays roles in AP1G1/AP-1-mediated protein trafficking including the trafficking of transferrin from early to recycling endosomes, and the membrane trafficking of furin and the lysosomal enzyme cathepsin D between the trans-Golgi network (TGN) and endosomes (PubMed:15758025). {ECO:0000269|PubMed:15758025}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneSTRNchr2:37096697chr2:37208937ENST00000263918-111853_120499781.0Coiled coilOntology_term=ECO:0000255
HgeneSTRNchr2:37096697chr2:37208937ENST00000379213-111853_120450732.0Coiled coilOntology_term=ECO:0000255
HgeneSTRNchr2:37121041chr2:37293053ENST00000263918-71853_120310781.0Coiled coilOntology_term=ECO:0000255
HgeneSTRNchr2:37121041chr2:37293053ENST00000379213-81853_120298732.0Coiled coilOntology_term=ECO:0000255
HgeneSTRNchr2:37096697chr2:37208937ENST00000263918-1118149_166499781.0RegionCalmodulin-binding
HgeneSTRNchr2:37096697chr2:37208937ENST00000263918-111855_63499781.0RegionCaveolin-binding
HgeneSTRNchr2:37096697chr2:37208937ENST00000379213-1118149_166450732.0RegionCalmodulin-binding
HgeneSTRNchr2:37096697chr2:37208937ENST00000379213-111855_63450732.0RegionCaveolin-binding
HgeneSTRNchr2:37121041chr2:37293053ENST00000263918-718149_166310781.0RegionCalmodulin-binding
HgeneSTRNchr2:37121041chr2:37293053ENST00000263918-71855_63310781.0RegionCaveolin-binding
HgeneSTRNchr2:37121041chr2:37293053ENST00000379213-818149_166298732.0RegionCalmodulin-binding
HgeneSTRNchr2:37121041chr2:37293053ENST00000379213-81855_63298732.0RegionCaveolin-binding
HgeneSTRNchr2:37193373chr2:37216002ENST00000263918-11855_6378781.0RegionCaveolin-binding
HgeneSTRNchr2:37193373chr2:37216002ENST00000379213-21855_6366732.0RegionCaveolin-binding
HgeneSTRNchr2:37096697chr2:37208937ENST00000263918-1118461_500499781.0RepeatNote=WD 1
TgeneHEATR5Bchr2:37121041chr2:37293053ENST000002330997361062_10993922072.0RepeatNote=HEAT 2
TgeneHEATR5Bchr2:37121041chr2:37293053ENST000002330997361290_13273922072.0RepeatNote=HEAT 3
TgeneHEATR5Bchr2:37121041chr2:37293053ENST00000233099736848_8853922072.0RepeatNote=HEAT 1
TgeneHEATR5Bchr2:37121041chr2:37293053ENST000003545317351062_10993921983.0RepeatNote=HEAT 2
TgeneHEATR5Bchr2:37121041chr2:37293053ENST000003545317351290_13273921983.0RepeatNote=HEAT 3
TgeneHEATR5Bchr2:37121041chr2:37293053ENST00000354531735848_8853921983.0RepeatNote=HEAT 1

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneSTRNchr2:37193373chr2:37216002ENST00000263918-11853_12078781.0Coiled coilOntology_term=ECO:0000255
HgeneSTRNchr2:37193373chr2:37216002ENST00000379213-21853_12066732.0Coiled coilOntology_term=ECO:0000255
HgeneSTRNchr2:37193373chr2:37216002ENST00000263918-118149_16678781.0RegionCalmodulin-binding
HgeneSTRNchr2:37193373chr2:37216002ENST00000379213-218149_16666732.0RegionCalmodulin-binding
HgeneSTRNchr2:37096697chr2:37208937ENST00000263918-1118514_553499781.0RepeatNote=WD 2
HgeneSTRNchr2:37096697chr2:37208937ENST00000263918-1118567_606499781.0RepeatNote=WD 3
HgeneSTRNchr2:37096697chr2:37208937ENST00000263918-1118662_701499781.0RepeatNote=WD 4
HgeneSTRNchr2:37096697chr2:37208937ENST00000263918-1118704_743499781.0RepeatNote=WD 5
HgeneSTRNchr2:37096697chr2:37208937ENST00000263918-1118750_779499781.0RepeatNote=WD 6
HgeneSTRNchr2:37096697chr2:37208937ENST00000379213-1118461_500450732.0RepeatNote=WD 1
HgeneSTRNchr2:37096697chr2:37208937ENST00000379213-1118514_553450732.0RepeatNote=WD 2
HgeneSTRNchr2:37096697chr2:37208937ENST00000379213-1118567_606450732.0RepeatNote=WD 3
HgeneSTRNchr2:37096697chr2:37208937ENST00000379213-1118662_701450732.0RepeatNote=WD 4
HgeneSTRNchr2:37096697chr2:37208937ENST00000379213-1118704_743450732.0RepeatNote=WD 5
HgeneSTRNchr2:37096697chr2:37208937ENST00000379213-1118750_779450732.0RepeatNote=WD 6
HgeneSTRNchr2:37121041chr2:37293053ENST00000263918-718461_500310781.0RepeatNote=WD 1
HgeneSTRNchr2:37121041chr2:37293053ENST00000263918-718514_553310781.0RepeatNote=WD 2
HgeneSTRNchr2:37121041chr2:37293053ENST00000263918-718567_606310781.0RepeatNote=WD 3
HgeneSTRNchr2:37121041chr2:37293053ENST00000263918-718662_701310781.0RepeatNote=WD 4
HgeneSTRNchr2:37121041chr2:37293053ENST00000263918-718704_743310781.0RepeatNote=WD 5
HgeneSTRNchr2:37121041chr2:37293053ENST00000263918-718750_779310781.0RepeatNote=WD 6
HgeneSTRNchr2:37121041chr2:37293053ENST00000379213-818461_500298732.0RepeatNote=WD 1
HgeneSTRNchr2:37121041chr2:37293053ENST00000379213-818514_553298732.0RepeatNote=WD 2
HgeneSTRNchr2:37121041chr2:37293053ENST00000379213-818567_606298732.0RepeatNote=WD 3
HgeneSTRNchr2:37121041chr2:37293053ENST00000379213-818662_701298732.0RepeatNote=WD 4
HgeneSTRNchr2:37121041chr2:37293053ENST00000379213-818704_743298732.0RepeatNote=WD 5
HgeneSTRNchr2:37121041chr2:37293053ENST00000379213-818750_779298732.0RepeatNote=WD 6
HgeneSTRNchr2:37193373chr2:37216002ENST00000263918-118461_50078781.0RepeatNote=WD 1
HgeneSTRNchr2:37193373chr2:37216002ENST00000263918-118514_55378781.0RepeatNote=WD 2
HgeneSTRNchr2:37193373chr2:37216002ENST00000263918-118567_60678781.0RepeatNote=WD 3
HgeneSTRNchr2:37193373chr2:37216002ENST00000263918-118662_70178781.0RepeatNote=WD 4
HgeneSTRNchr2:37193373chr2:37216002ENST00000263918-118704_74378781.0RepeatNote=WD 5
HgeneSTRNchr2:37193373chr2:37216002ENST00000263918-118750_77978781.0RepeatNote=WD 6
HgeneSTRNchr2:37193373chr2:37216002ENST00000379213-218461_50066732.0RepeatNote=WD 1
HgeneSTRNchr2:37193373chr2:37216002ENST00000379213-218514_55366732.0RepeatNote=WD 2
HgeneSTRNchr2:37193373chr2:37216002ENST00000379213-218567_60666732.0RepeatNote=WD 3
HgeneSTRNchr2:37193373chr2:37216002ENST00000379213-218662_70166732.0RepeatNote=WD 4
HgeneSTRNchr2:37193373chr2:37216002ENST00000379213-218704_74366732.0RepeatNote=WD 5
HgeneSTRNchr2:37193373chr2:37216002ENST00000379213-218750_77966732.0RepeatNote=WD 6
TgeneHEATR5Bchr2:37096697chr2:37208937ENST0000023309934361062_109919702072.0RepeatNote=HEAT 2
TgeneHEATR5Bchr2:37096697chr2:37208937ENST0000023309934361290_132719702072.0RepeatNote=HEAT 3
TgeneHEATR5Bchr2:37096697chr2:37208937ENST000002330993436848_88519702072.0RepeatNote=HEAT 1
TgeneHEATR5Bchr2:37096697chr2:37208937ENST0000035453133351062_109918811983.0RepeatNote=HEAT 2
TgeneHEATR5Bchr2:37096697chr2:37208937ENST0000035453133351290_132718811983.0RepeatNote=HEAT 3
TgeneHEATR5Bchr2:37096697chr2:37208937ENST000003545313335848_88518811983.0RepeatNote=HEAT 1
TgeneHEATR5Bchr2:37193373chr2:37216002ENST0000023309933361062_109918992072.0RepeatNote=HEAT 2
TgeneHEATR5Bchr2:37193373chr2:37216002ENST0000023309933361290_132718992072.0RepeatNote=HEAT 3
TgeneHEATR5Bchr2:37193373chr2:37216002ENST000002330993336848_88518992072.0RepeatNote=HEAT 1
TgeneHEATR5Bchr2:37193373chr2:37216002ENST0000035453132351062_109918101983.0RepeatNote=HEAT 2
TgeneHEATR5Bchr2:37193373chr2:37216002ENST0000035453132351290_132718101983.0RepeatNote=HEAT 3
TgeneHEATR5Bchr2:37193373chr2:37216002ENST000003545313235848_88518101983.0RepeatNote=HEAT 1


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Fusion Gene Sequence for STRN-HEATR5B


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>87738_87738_1_STRN-HEATR5B_STRN_chr2_37096697_ENST00000263918_HEATR5B_chr2_37208937_ENST00000233099_length(transcript)=2406nt_BP=1508nt
GCGGCCGCCATGGACGAGCAGGCGGGTCCCGGCGTCTTCTTCAGCAACAACCACCCGGGCGCCGGCGGTGCCAAGGGGCTCGGGCCTCTG
GCGGAGGCTGCCGCGGCCGGCGACGGGGCGGCTGCGGCGGGGGCGGCCCGAGCCCAGTACAGTCTCCCGGGGATCCTGCACTTCCTGCAG
CACGAGTGGGCCCGCTTCGAGGTGGAGAGAGCCCAGTGGGAGGTGGAGCGGGCGGAGCTGCAGGCCCAGATTGCCTTCCTGCAGGGAGAA
AGGAAGGGCCAAGAAAATTTGAAGAAGGATCTTGTGAGGAGGATCAAAATGTTGGAGTATGCTCTTAAACAGGAAAGAGCCAAATACCAC
AAGTTGAAATACGGGACAGAATTGAATCAGGGAGATATGAAGCCTCCAAGCTATGATTCTGATGAAGGTAATGAAACAGAAGTGCAGCCA
CAACAAAACAGCCAGTTAATGTGGAAACAAGGTCGACAACTACTCAGACAGTATCTACAGGAGGTGGGTTATACAGATACTATTCTAGAT
GTGAAATCTAAACGAGTGCGAGCTTTGTTGGGCTTTTCAAGTGATGTCACGGACAGGGAAGATGACAAAAATCAGGACTCAGTTGTAAAT
GGCACAGAGGCTGAAGTTAAAGAGACAGCAATGATTGCAAAATCTGAGTTAACAGATTCTGCCTCCGTGCTGGATAATTTCAAATTCCTT
GAAAGTGCAGCTGCAGATTTCAGTGATGAAGATGAAGATGATGATGTTGATGGAAGAGAGAAAAGCGTCATTGATACTTCAACAATTGTT
AGGAAAAAAGCATTGCCTGACAGCGGTGAAGATCGAGATACAAAAGAAGCTCTAAAGGAGTTTGACTTCTTGGTTACATCAGAGGAAGGA
GACAATGAATCTAGAAGTGCAGGCGATGGAACAGACTGGGAAAAGGAAGACCAGTGTCTCATGCCTGAAGCCTGGAATGTGGACCAGGGA
GTAATTACCAAACTCAAGGAACAATACAAAAAGGAGAGAAAGGGGAAAAAGGGGGTGAAGAGGCCCAATAGGTCAAAACTACAAGATATG
CTTGCTAATTTGAGAGATGTTGATGAACTTCCTTCATTGCAGCCATCTGTGGGTTCACCTTCCAGACCCAGCAGCTCCAGGCTTCCTGAA
CATGAAATTAATAGGGCAGATGAAGTGGAAGCATTGACATTTCCTCCTTCTTCTGGAAAGTCATTCATCATGGGAGCAGATGAAGCCCTT
GAAAGTGAACTGGGACTTGGAGAACTAGCAGGCCTTACGGTGGCCAATGAAGCAGACTCACTAACTTATGATATAGCAAACAATAAAGAT
GCATTGAGGAAGACATGGAACCCTAAGTTTACATTGAGAAGTCACTTTGATGGCATCCGAGCCCTTGCTTTCCATCCCATTGAGCCTGTT
TTGATAACAGCATCAGAGGATCACACATTAAAAATGTGGAATTTACAGAAAACAGCCCCAGCCAAAAAGAGTCCAGCTACTTGCTCTTTT
AGTTCCCACTTTGATATCTTACCTGCTGGATGAAAATTCTTTTGCCTCAGCAAGTTCAGCTTCCAAAGATCTTCATGAGTTTGCACTCCA
GAATTTAATGCATATTGGACCTCTGTATCCACATGCTTTCAAGACAGTAATGGGGGCTGCTCCTGAGTTGAAAGTGCGTCTAGAAACTGC
CGTTCGAGCAAGCCAAGCGAGCAAAGCTAAAGCGGCTGCCAGACAACCAGCCCCCGCCATACATTCTGCACCAACAATTAAGCTAAAAAC
AAGTTTTTTTTAATTTGTAATTTCATTTATTTGTATTTATGTTGTCAACTAGCCCCTAATTAGTGATGGCCACTGTATCATTCCAGGCTA
CCTATGGGTTCTGTTTTATTTGTATATTGGTATTATAGTGCTTCCAAGTAGGTTAAGTGAAATAATGCTCACACCACTTATTGATTTTTA
AGGAGTGATTTTTTTTATCATGTGGTGAATATGTTTTCATTTTCCTCCTAATAATGTTTCTCTTTTGTTAACTTATTTATTTTTCAAACA
CTGAGCCATAGTCTTAAATTTAAATGCTAAAAACAATTGTATCATGTAGTCGGGCAGCCTATTGATACTGTCAGGGGAAAAAAATGGGTC
AGAACTCAGCATCTGTCATGAAAAAAATCAATTGAAAAACAAGCAGATTTTAAATTTTGAAGTAATCAAAATAATGGAAAGTGTCTGTTT
TGTGGTGTATATACTATGAATAAAATCACAGCATTTTCTAAGCATTTCCCAAAATGTCCTTATCTTTCTGATGGATCTTTTAGCTTTCAT

>87738_87738_1_STRN-HEATR5B_STRN_chr2_37096697_ENST00000263918_HEATR5B_chr2_37208937_ENST00000233099_length(amino acids)=517AA_BP=500
MDEQAGPGVFFSNNHPGAGGAKGLGPLAEAAAAGDGAAAAGAARAQYSLPGILHFLQHEWARFEVERAQWEVERAELQAQIAFLQGERKG
QENLKKDLVRRIKMLEYALKQERAKYHKLKYGTELNQGDMKPPSYDSDEGNETEVQPQQNSQLMWKQGRQLLRQYLQEVGYTDTILDVKS
KRVRALLGFSSDVTDREDDKNQDSVVNGTEAEVKETAMIAKSELTDSASVLDNFKFLESAAADFSDEDEDDDVDGREKSVIDTSTIVRKK
ALPDSGEDRDTKEALKEFDFLVTSEEGDNESRSAGDGTDWEKEDQCLMPEAWNVDQGVITKLKEQYKKERKGKKGVKRPNRSKLQDMLAN
LRDVDELPSLQPSVGSPSRPSSSRLPEHEINRADEVEALTFPPSSGKSFIMGADEALESELGLGELAGLTVANEADSLTYDIANNKDALR

--------------------------------------------------------------
>87738_87738_2_STRN-HEATR5B_STRN_chr2_37096697_ENST00000263918_HEATR5B_chr2_37208937_ENST00000354531_length(transcript)=2293nt_BP=1508nt
GCGGCCGCCATGGACGAGCAGGCGGGTCCCGGCGTCTTCTTCAGCAACAACCACCCGGGCGCCGGCGGTGCCAAGGGGCTCGGGCCTCTG
GCGGAGGCTGCCGCGGCCGGCGACGGGGCGGCTGCGGCGGGGGCGGCCCGAGCCCAGTACAGTCTCCCGGGGATCCTGCACTTCCTGCAG
CACGAGTGGGCCCGCTTCGAGGTGGAGAGAGCCCAGTGGGAGGTGGAGCGGGCGGAGCTGCAGGCCCAGATTGCCTTCCTGCAGGGAGAA
AGGAAGGGCCAAGAAAATTTGAAGAAGGATCTTGTGAGGAGGATCAAAATGTTGGAGTATGCTCTTAAACAGGAAAGAGCCAAATACCAC
AAGTTGAAATACGGGACAGAATTGAATCAGGGAGATATGAAGCCTCCAAGCTATGATTCTGATGAAGGTAATGAAACAGAAGTGCAGCCA
CAACAAAACAGCCAGTTAATGTGGAAACAAGGTCGACAACTACTCAGACAGTATCTACAGGAGGTGGGTTATACAGATACTATTCTAGAT
GTGAAATCTAAACGAGTGCGAGCTTTGTTGGGCTTTTCAAGTGATGTCACGGACAGGGAAGATGACAAAAATCAGGACTCAGTTGTAAAT
GGCACAGAGGCTGAAGTTAAAGAGACAGCAATGATTGCAAAATCTGAGTTAACAGATTCTGCCTCCGTGCTGGATAATTTCAAATTCCTT
GAAAGTGCAGCTGCAGATTTCAGTGATGAAGATGAAGATGATGATGTTGATGGAAGAGAGAAAAGCGTCATTGATACTTCAACAATTGTT
AGGAAAAAAGCATTGCCTGACAGCGGTGAAGATCGAGATACAAAAGAAGCTCTAAAGGAGTTTGACTTCTTGGTTACATCAGAGGAAGGA
GACAATGAATCTAGAAGTGCAGGCGATGGAACAGACTGGGAAAAGGAAGACCAGTGTCTCATGCCTGAAGCCTGGAATGTGGACCAGGGA
GTAATTACCAAACTCAAGGAACAATACAAAAAGGAGAGAAAGGGGAAAAAGGGGGTGAAGAGGCCCAATAGGTCAAAACTACAAGATATG
CTTGCTAATTTGAGAGATGTTGATGAACTTCCTTCATTGCAGCCATCTGTGGGTTCACCTTCCAGACCCAGCAGCTCCAGGCTTCCTGAA
CATGAAATTAATAGGGCAGATGAAGTGGAAGCATTGACATTTCCTCCTTCTTCTGGAAAGTCATTCATCATGGGAGCAGATGAAGCCCTT
GAAAGTGAACTGGGACTTGGAGAACTAGCAGGCCTTACGGTGGCCAATGAAGCAGACTCACTAACTTATGATATAGCAAACAATAAAGAT
GCATTGAGGAAGACATGGAACCCTAAGTTTACATTGAGAAGTCACTTTGATGGCATCCGAGCCCTTGCTTTCCATCCCATTGAGCCTGTT
TTGATAACAGCATCAGAGGATCACACATTAAAAATGTGGAATTTACAGAAAACAGCCCCAGCCAAAAAGAGTCCAGCTACTTGCTCTTTT
AGTTCCCACTTTGATATCTTACCTGCTGGATGAAAATTCTTTTGCCTCAGCAAGTTCAGCTTCCAAAGATCTTCATGAGTTTGCACTCCA
GAATTTAATGCATATTGGACCTCTGTATCCACATGCTTTCAAGACAGTAATGGGGGCTGCTCCTGAGTTGAAAGTGCGTCTAGAAACTGC
CGTTCGAGCAAGCCAAGCGAGCAAAGCTAAAGCGGCTGCCAGACAACCAGCCCCCGCCATACATTCTGCACCAACAATTAAGCTAAAAAC
AAGTTTTTTTTAATTTGTAATTTCATTTATTTGTATTTATGTTGTCAACTAGCCCCTAATTAGTGATGGCCACTGTATCATTCCAGGCTA
CCTATGGGTTCTGTTTTATTTGTATATTGGTATTATAGTGCTTCCAAGTAGGTTAAGTGAAATAATGCTCACACCACTTATTGATTTTTA
AGGAGTGATTTTTTTTATCATGTGGTGAATATGTTTTCATTTTCCTCCTAATAATGTTTCTCTTTTGTTAACTTATTTATTTTTCAAACA
CTGAGCCATAGTCTTAAATTTAAATGCTAAAAACAATTGTATCATGTAGTCGGGCAGCCTATTGATACTGTCAGGGGAAAAAAATGGGTC
AGAACTCAGCATCTGTCATGAAAAAAATCAATTGAAAAACAAGCAGATTTTAAATTTTGAAGTAATCAAAATAATGGAAAGTGTCTGTTT

>87738_87738_2_STRN-HEATR5B_STRN_chr2_37096697_ENST00000263918_HEATR5B_chr2_37208937_ENST00000354531_length(amino acids)=517AA_BP=500
MDEQAGPGVFFSNNHPGAGGAKGLGPLAEAAAAGDGAAAAGAARAQYSLPGILHFLQHEWARFEVERAQWEVERAELQAQIAFLQGERKG
QENLKKDLVRRIKMLEYALKQERAKYHKLKYGTELNQGDMKPPSYDSDEGNETEVQPQQNSQLMWKQGRQLLRQYLQEVGYTDTILDVKS
KRVRALLGFSSDVTDREDDKNQDSVVNGTEAEVKETAMIAKSELTDSASVLDNFKFLESAAADFSDEDEDDDVDGREKSVIDTSTIVRKK
ALPDSGEDRDTKEALKEFDFLVTSEEGDNESRSAGDGTDWEKEDQCLMPEAWNVDQGVITKLKEQYKKERKGKKGVKRPNRSKLQDMLAN
LRDVDELPSLQPSVGSPSRPSSSRLPEHEINRADEVEALTFPPSSGKSFIMGADEALESELGLGELAGLTVANEADSLTYDIANNKDALR

--------------------------------------------------------------
>87738_87738_3_STRN-HEATR5B_STRN_chr2_37096697_ENST00000379213_HEATR5B_chr2_37208937_ENST00000233099_length(transcript)=2250nt_BP=1352nt
ATGGACGAGCAGGCGGGTCCCGGCGTCTTCTTCAGCAACAACCACCCGGGCGCCGGCGGTGCCAAGGGGCTCGGGCCTCTGGCGGGGGCG
GCCCGAGCCCAGTACAGTCTCCCGGGGATCCTGCACTTCCTGCAGCACGAGTGGGCCCGCTTCGAGGTGGAGAGAGCCCAGTGGGAGGTG
GAGCGGGCGGAGCTGCAGGCCCAGATTGCCTTCCTGCAGGGAGAAAGGAAGGGCCAAGAAAATTTGAAGAAGGATCTTGTGAGGAGGATC
AAAATGTTGGAGTATGCTCTTAAACAGGAAAGAGCCAAATACCACAAGTTGAAATACGGGACAGAATTGAATCAGGGAGATATGAAGCCT
CCAAGCTATGATTCTGATGAAGGTAATGAAACAGAAGTGCAGCCACAACAAAACAGCCAGTTAATGTGGAAACAAGGTCGACAACTACTC
AGACAGTATCTACAGGAGGTGGGTTATACAGATACTATTCTAGATGTGAAATCTAAACGAGTGCGAGCTTTGTTGGGCTTTTCAAGTGAT
GTCACGGACAGGGAAGATGACAAAAATCAGGACTCAGTTGTAAATGGCACAGAGGCTGAAGTTAAAGAGACAGCAATGATTGCAAAATCT
GAGTTAACAGATTCTGCCTCCGTGCTGGATAATTTCAAATTCCTTGAAAGTGCAGCTGCAGATTTCAGTGATGAAGATGAAGATGATGAT
GTTGATGGAAGAGAGAAAAGCGTCATTGATACTTCAACAATTGTTAGGAAAAAAGCATTGCCTGACAGCGGTGAAGATCGAGATACAAAA
GAAGCTCTAAAGGAGTTTGACTTCTTGGTTACATCAGAGGAAGGAGACAATGAATCTAGAAGTGCAGGCGATGGAACAGACTGGGGGCCC
AATAGGTCAAAACTACAAGATATGCTTGCTAATTTGAGAGATGTTGATGAACTTCCTTCATTGCAGCCATCTGTGGGTTCACCTTCCAGA
CCCAGCAGCTCCAGGCTTCCTGAACATGAAATTAATAGGGCAGATGAAGTGGAAGCATTGACATTTCCTCCTTCTTCTGGAAAGTCATTC
ATCATGGGAGCAGATGAAGCCCTTGAAAGTGAACTGGGACTTGGAGAACTAGCAGGCCTTACGGTGGCCAATGAAGCAGACTCACTAACT
TATGATATAGCAAACAATAAAGATGCATTGAGGAAGACATGGAACCCTAAGTTTACATTGAGAAGTCACTTTGATGGCATCCGAGCCCTT
GCTTTCCATCCCATTGAGCCTGTTTTGATAACAGCATCAGAGGATCACACATTAAAAATGTGGAATTTACAGAAAACAGCCCCAGCCAAA
AAGAGTCCAGCTACTTGCTCTTTTAGTTCCCACTTTGATATCTTACCTGCTGGATGAAAATTCTTTTGCCTCAGCAAGTTCAGCTTCCAA
AGATCTTCATGAGTTTGCACTCCAGAATTTAATGCATATTGGACCTCTGTATCCACATGCTTTCAAGACAGTAATGGGGGCTGCTCCTGA
GTTGAAAGTGCGTCTAGAAACTGCCGTTCGAGCAAGCCAAGCGAGCAAAGCTAAAGCGGCTGCCAGACAACCAGCCCCCGCCATACATTC
TGCACCAACAATTAAGCTAAAAACAAGTTTTTTTTAATTTGTAATTTCATTTATTTGTATTTATGTTGTCAACTAGCCCCTAATTAGTGA
TGGCCACTGTATCATTCCAGGCTACCTATGGGTTCTGTTTTATTTGTATATTGGTATTATAGTGCTTCCAAGTAGGTTAAGTGAAATAAT
GCTCACACCACTTATTGATTTTTAAGGAGTGATTTTTTTTATCATGTGGTGAATATGTTTTCATTTTCCTCCTAATAATGTTTCTCTTTT
GTTAACTTATTTATTTTTCAAACACTGAGCCATAGTCTTAAATTTAAATGCTAAAAACAATTGTATCATGTAGTCGGGCAGCCTATTGAT
ACTGTCAGGGGAAAAAAATGGGTCAGAACTCAGCATCTGTCATGAAAAAAATCAATTGAAAAACAAGCAGATTTTAAATTTTGAAGTAAT
CAAAATAATGGAAAGTGTCTGTTTTGTGGTGTATATACTATGAATAAAATCACAGCATTTTCTAAGCATTTCCCAAAATGTCCTTATCTT
TCTGATGGATCTTTTAGCTTTCATATCAAATTACTAAATTATGCTATGTATATTTTAGTTGGTAACAATTAAAATTCTCATTTAAAGGTT

>87738_87738_3_STRN-HEATR5B_STRN_chr2_37096697_ENST00000379213_HEATR5B_chr2_37208937_ENST00000233099_length(amino acids)=468AA_BP=451
MDEQAGPGVFFSNNHPGAGGAKGLGPLAGAARAQYSLPGILHFLQHEWARFEVERAQWEVERAELQAQIAFLQGERKGQENLKKDLVRRI
KMLEYALKQERAKYHKLKYGTELNQGDMKPPSYDSDEGNETEVQPQQNSQLMWKQGRQLLRQYLQEVGYTDTILDVKSKRVRALLGFSSD
VTDREDDKNQDSVVNGTEAEVKETAMIAKSELTDSASVLDNFKFLESAAADFSDEDEDDDVDGREKSVIDTSTIVRKKALPDSGEDRDTK
EALKEFDFLVTSEEGDNESRSAGDGTDWGPNRSKLQDMLANLRDVDELPSLQPSVGSPSRPSSSRLPEHEINRADEVEALTFPPSSGKSF
IMGADEALESELGLGELAGLTVANEADSLTYDIANNKDALRKTWNPKFTLRSHFDGIRALAFHPIEPVLITASEDHTLKMWNLQKTAPAK

--------------------------------------------------------------
>87738_87738_4_STRN-HEATR5B_STRN_chr2_37096697_ENST00000379213_HEATR5B_chr2_37208937_ENST00000354531_length(transcript)=2137nt_BP=1352nt
ATGGACGAGCAGGCGGGTCCCGGCGTCTTCTTCAGCAACAACCACCCGGGCGCCGGCGGTGCCAAGGGGCTCGGGCCTCTGGCGGGGGCG
GCCCGAGCCCAGTACAGTCTCCCGGGGATCCTGCACTTCCTGCAGCACGAGTGGGCCCGCTTCGAGGTGGAGAGAGCCCAGTGGGAGGTG
GAGCGGGCGGAGCTGCAGGCCCAGATTGCCTTCCTGCAGGGAGAAAGGAAGGGCCAAGAAAATTTGAAGAAGGATCTTGTGAGGAGGATC
AAAATGTTGGAGTATGCTCTTAAACAGGAAAGAGCCAAATACCACAAGTTGAAATACGGGACAGAATTGAATCAGGGAGATATGAAGCCT
CCAAGCTATGATTCTGATGAAGGTAATGAAACAGAAGTGCAGCCACAACAAAACAGCCAGTTAATGTGGAAACAAGGTCGACAACTACTC
AGACAGTATCTACAGGAGGTGGGTTATACAGATACTATTCTAGATGTGAAATCTAAACGAGTGCGAGCTTTGTTGGGCTTTTCAAGTGAT
GTCACGGACAGGGAAGATGACAAAAATCAGGACTCAGTTGTAAATGGCACAGAGGCTGAAGTTAAAGAGACAGCAATGATTGCAAAATCT
GAGTTAACAGATTCTGCCTCCGTGCTGGATAATTTCAAATTCCTTGAAAGTGCAGCTGCAGATTTCAGTGATGAAGATGAAGATGATGAT
GTTGATGGAAGAGAGAAAAGCGTCATTGATACTTCAACAATTGTTAGGAAAAAAGCATTGCCTGACAGCGGTGAAGATCGAGATACAAAA
GAAGCTCTAAAGGAGTTTGACTTCTTGGTTACATCAGAGGAAGGAGACAATGAATCTAGAAGTGCAGGCGATGGAACAGACTGGGGGCCC
AATAGGTCAAAACTACAAGATATGCTTGCTAATTTGAGAGATGTTGATGAACTTCCTTCATTGCAGCCATCTGTGGGTTCACCTTCCAGA
CCCAGCAGCTCCAGGCTTCCTGAACATGAAATTAATAGGGCAGATGAAGTGGAAGCATTGACATTTCCTCCTTCTTCTGGAAAGTCATTC
ATCATGGGAGCAGATGAAGCCCTTGAAAGTGAACTGGGACTTGGAGAACTAGCAGGCCTTACGGTGGCCAATGAAGCAGACTCACTAACT
TATGATATAGCAAACAATAAAGATGCATTGAGGAAGACATGGAACCCTAAGTTTACATTGAGAAGTCACTTTGATGGCATCCGAGCCCTT
GCTTTCCATCCCATTGAGCCTGTTTTGATAACAGCATCAGAGGATCACACATTAAAAATGTGGAATTTACAGAAAACAGCCCCAGCCAAA
AAGAGTCCAGCTACTTGCTCTTTTAGTTCCCACTTTGATATCTTACCTGCTGGATGAAAATTCTTTTGCCTCAGCAAGTTCAGCTTCCAA
AGATCTTCATGAGTTTGCACTCCAGAATTTAATGCATATTGGACCTCTGTATCCACATGCTTTCAAGACAGTAATGGGGGCTGCTCCTGA
GTTGAAAGTGCGTCTAGAAACTGCCGTTCGAGCAAGCCAAGCGAGCAAAGCTAAAGCGGCTGCCAGACAACCAGCCCCCGCCATACATTC
TGCACCAACAATTAAGCTAAAAACAAGTTTTTTTTAATTTGTAATTTCATTTATTTGTATTTATGTTGTCAACTAGCCCCTAATTAGTGA
TGGCCACTGTATCATTCCAGGCTACCTATGGGTTCTGTTTTATTTGTATATTGGTATTATAGTGCTTCCAAGTAGGTTAAGTGAAATAAT
GCTCACACCACTTATTGATTTTTAAGGAGTGATTTTTTTTATCATGTGGTGAATATGTTTTCATTTTCCTCCTAATAATGTTTCTCTTTT
GTTAACTTATTTATTTTTCAAACACTGAGCCATAGTCTTAAATTTAAATGCTAAAAACAATTGTATCATGTAGTCGGGCAGCCTATTGAT
ACTGTCAGGGGAAAAAAATGGGTCAGAACTCAGCATCTGTCATGAAAAAAATCAATTGAAAAACAAGCAGATTTTAAATTTTGAAGTAAT

>87738_87738_4_STRN-HEATR5B_STRN_chr2_37096697_ENST00000379213_HEATR5B_chr2_37208937_ENST00000354531_length(amino acids)=468AA_BP=451
MDEQAGPGVFFSNNHPGAGGAKGLGPLAGAARAQYSLPGILHFLQHEWARFEVERAQWEVERAELQAQIAFLQGERKGQENLKKDLVRRI
KMLEYALKQERAKYHKLKYGTELNQGDMKPPSYDSDEGNETEVQPQQNSQLMWKQGRQLLRQYLQEVGYTDTILDVKSKRVRALLGFSSD
VTDREDDKNQDSVVNGTEAEVKETAMIAKSELTDSASVLDNFKFLESAAADFSDEDEDDDVDGREKSVIDTSTIVRKKALPDSGEDRDTK
EALKEFDFLVTSEEGDNESRSAGDGTDWGPNRSKLQDMLANLRDVDELPSLQPSVGSPSRPSSSRLPEHEINRADEVEALTFPPSSGKSF
IMGADEALESELGLGELAGLTVANEADSLTYDIANNKDALRKTWNPKFTLRSHFDGIRALAFHPIEPVLITASEDHTLKMWNLQKTAPAK

--------------------------------------------------------------
>87738_87738_5_STRN-HEATR5B_STRN_chr2_37121041_ENST00000263918_HEATR5B_chr2_37293053_ENST00000233099_length(transcript)=6572nt_BP=940nt
GCGGCCGCCATGGACGAGCAGGCGGGTCCCGGCGTCTTCTTCAGCAACAACCACCCGGGCGCCGGCGGTGCCAAGGGGCTCGGGCCTCTG
GCGGAGGCTGCCGCGGCCGGCGACGGGGCGGCTGCGGCGGGGGCGGCCCGAGCCCAGTACAGTCTCCCGGGGATCCTGCACTTCCTGCAG
CACGAGTGGGCCCGCTTCGAGGTGGAGAGAGCCCAGTGGGAGGTGGAGCGGGCGGAGCTGCAGGCCCAGATTGCCTTCCTGCAGGGAGAA
AGGAAGGGCCAAGAAAATTTGAAGAAGGATCTTGTGAGGAGGATCAAAATGTTGGAGTATGCTCTTAAACAGGAAAGAGCCAAATACCAC
AAGTTGAAATACGGGACAGAATTGAATCAGGGAGATATGAAGCCTCCAAGCTATGATTCTGATGAAGGTAATGAAACAGAAGTGCAGCCA
CAACAAAACAGCCAGTTAATGTGGAAACAAGGTCGACAACTACTCAGACAGTATCTACAGGAGGTGGGTTATACAGATACTATTCTAGAT
GTGAAATCTAAACGAGTGCGAGCTTTGTTGGGCTTTTCAAGTGATGTCACGGACAGGGAAGATGACAAAAATCAGGACTCAGTTGTAAAT
GGCACAGAGGCTGAAGTTAAAGAGACAGCAATGATTGCAAAATCTGAGTTAACAGATTCTGCCTCCGTGCTGGATAATTTCAAATTCCTT
GAAAGTGCAGCTGCAGATTTCAGTGATGAAGATGAAGATGATGATGTTGATGGAAGAGAGAAAAGCGTCATTGATACTTCAACAATTGTT
AGGAAAAAAGCATTGCCTGACAGCGGTGAAGATCGAGATACAAAAGAAGCTCTAAAGGAGTTTGACTTCTTGGTTACATCAGAGGAAGGA
GACAATGAATCTAGAAGTGCAGGCGATGGAACAGACTGGGAAGCAGTAGTGAATGACACAAGTGGAGAAAACAAATCTGGCGCAGCAGAC
ATTGCAGCAAGCCAGCATGTGATGGTCTGTGCCCTCCAGGAACTCGGGAGCCTGGTGCAGAGCTTGAATGCCACCGCATCCCCTCTTATT
CAAGAAGCATCTATAGGGCTTTTGGAGATTGTGACTTCAGTGCTGCTTCATCCAAGCATGGCTGCCCGACTTGCTGCTGCATGGTGTTTG
CGCTGTGTGGCTGTGGCATTACCTTTCCAGCTGACACCATTTCTAGACAGGTGTGCAGAACGGCTCAACAACTTGAAGACCTCACCAGAA
GCTGTCAGTGGATATAGTTTTGCAATGGCTGCTTTGTTAGGTGGAGTACATCAGTGTCCTTTGGGCATTCCTCATGCCAAAGGAAAGATG
GTAGTTAGTATTGCTGAAGATCTTTTACGAACTGCTGCCCAAAATAGCAGGCTATCTTTACAGCGCACCCAAGCTGGCTGGCTTTTACTT
GGAGCACTTATGACTTTAGGACCATCTGTCGTTCGTTACCATCTGCCCAAGATGTTGTTATTGTGGCGAAATGTTTTCCCACGTTCCTTA
AAGGAATTGGAAGCTGAGAAGGCCCGAGGCGATTCTTTTACCTGGCAGGTAACTTTGGAAGGTCGTGCTGGAGCTCTATGTGCCATGAGG
AGCTTCGTTGCACATTGTCCTGAGCTACTAACTGAAGATGTGATTCGAAAATTGATGACCCCTATTGAATGTGCCATGACTATGATGTCA
CACATTCCATCTGTAATGAAAGCCCATGGAGCTCATCTGAAAGCTAGTGCTGCAATGGTCCGTTTAAGACTTTATGATATCTTGGCTTTG
TTACCTCCAAAAACTTATGAAGGATCTTTTAATGCACTTCTTAGAGAACTGGTAGCGGAATTCACTTTGACTGACAACTCAGCCAACACA
ACTACTTCCCTCCTCAGATCCCTCTGCCATTATGATGATAGTGTTCTTCTTGGTTCTTGGCTTCAGGAAACTGATCATAAATCAATTGAA
GACCAGCTCCAGCCAAACAGTGCCTCTGGAAGTGGGGCTCTGGAGCATGATCCTTCCTCTATTTATTTACGCATACCTGCTGGAGAAGCA
GTACCTGGTCCCCTCCCTCTCGGAGTCTCAGTCATTGATGCTTCTGTGGCCCTTTTTGGTGTAGTGTTTCCTCATGTTTCTTATAAACAC
CGATTACAAATGTTGGATCACTTTGCTGAATGTGTTAAACAAGCTAAAGGTGTCCGCCAGCAGGCTGTGCAGCTTAACATATTTACTGCT
GTTCTTAGTGCACTAAAGGGCTTAGCTGAAAACAAAAGTACTTTAGGACCTGAGGAAGTTCGTAAATCTGCCCTGACACTGGTTATGGGT
CCTCTGGACAACCCAAACCCCATCTTACGTTGTGCAGCGGGGGAAGCTCTTGGAAGAATGGCTCAGGTGGTTGGAGAAGCAACTTTTATT
GCTAGAATGGCCCAATATAGCTTTGACAAGTTGAAATCGGCTCGAGATGTTGTATCTAGGACTGGTCATTCATTGGCTCTTGGTTGTTTG
CATCGTTATGTTGGTGGAATAGGCTCAGGACAACATCTGAAGACCAGTGTCAGCATTTTATTGGCTCTAGCACAAGATGGGACATCCCCT
GAAGTCCAGACTTGGTCTCTTCATTCACTTGCTTTGATAGTGGATTCTAGTGGTCCGATGTATCGTGGCTATGTGGAACCAACATTATCT
CTAGTTCTTACCTTGCTGTTGACAGTTCCGCCTTCACATACAGAAGTTCATCAGTGTTTGGGTCGATGCTTGGGTGCTATAATAACTACT
GTTGGCCCTGAACTACAAGGGAATGGAGCAACAACTTCTACAATTCGTTCCTCTTGTTTGGTGGGTTGTGCAATAACACAAGACCATTCA
GATTCTCTTGTTCAGGCAGCTGCCATATCTTGCCTTCAGCAGCTTCACATGTTTGCACCACGACATGTCAATCTATCTAGCCTTGTTCCT
AGCCTTTGTGTTCACTTATGTAGTTCCCATTTGTTACTTCGACGAGCAGCTGTGGCATGTCTTCGGCAACTTGCACAAAGAGAAGCAGCG
GAAGTATGTGAATATGCCATGAGCCTGGCAAAAAATACAGGGGACAAAGAGAGCAGTAGTGCCAATGTCAGTCCTTTTGCCCCTGGGGTT
AGTTCTCGAACTGATATCCATTGCCGGCACCAAGGTGTTAATATAACAGAAACTGGTCTTGAGGGACTTCTTTTTGGAATGCTAGACCGG
GAGACAGATCGAAAATTATGTTCTGATATTCATGACACTTTGGGACATATGCTTTCTTCGCTGGCAGTAGAAAAACTTTCTCATTGGCTA
ATGCTTTGTAAAGATGTCCTGGCAGCTTCTAGTGATATGAGTACTGCAACTCTCTTAAGTAGTGGAAAAGATGAAGAAGCTGAAAAGAAA
GATGAGATGGATGATGATACCATGTTTACCACGTTAGGTGAAGAAGATAAATCAAAGCCCTTTGTGGCCCCTCGCTGGGCCACTCGAGTA
TTTGCTGCCGATTGCCTGTGTCGAATCATCAATTTGTGTGAGAATGCAGACCAGGCTCACTTTGATCTTGCCTTGGCACGTTCTGCTAAA
CTTCGAAACCCTACAAATGACCTCTTGGTACTTCATCTCTCTGACCTCATTCGCATGGCATTCATGGCTGCAACTGATCATAGCAACCAG
CTGCGAATGGCTGGGCTCCAGGCGCTTGAAGACATTATCAAGAAGTTTGCGTCTGTGCCTGAGCCAGAATTTCCAGGTCATGTGATACTG
GAGCAGTATCAGGCTAATGTGGGAGCTGCTCTAAGACCAGCCTTTTCACAAGATACACCATCAGATATAATAGCGAAAGCTTGCCAGGTA
TGTAGTACATGGATAGGAAGTGGAGTTGTCAGTGATCTCAATGATCTCCGTCGAGTACACAATCTTCTTGTTTCTTCTCTGGACAAAGTT
CAGGCTGGAAAAGGATCTTCCAGCCAGCTGTACCGAGAGAGTGCCACGACCATGGAAAAACTGGCTGTTCTCAAAGCTTGGGCAGAGGTA
TATGTGGTCGCTATGAATATTAAAAAGGAAGCAGAGTCAAAACCAAAAAGAGCAATTAAAAATACTGACGATGATGATGACGACTGTGGT
ACCATCGATGAACTGCCACCAGATAGTTTAATAACACTGGTACAACCTGAACTACCAACACTCAGTCGCCTGTGGTTAGCAGCATTAAAA
GATTATGCACTCTTGACTTTACCAGCCGAATTTTCTAGTCAGCTTCCTCCAGATGGTGGAGCATTTTATACCCCTGAAACTATTGATACA
GCTAGACTTCACTATCGGAATTCCTGGGCCCCAATTCTCCATGCGGTGGCACTTTGGTTAAATAGCACAGGATTTACGTGCTCAGAGTCT
ACAGAAGCAGCAGCAATATCTGGTTTACAAAAACGTTCTACATCTGTCAATTTAAACCAGGCATCAGGAGCAGTGGGTAGTGCTAAATCT
TTGCCAGAAATTAACAAAGACAGAATGCATCTGATTTTAGGTGTGAGTATACAGTTTCTTTGTTCCCCTAGACCTGAGGAGCCCATTGAA
CATGTTACAGCATGCCTGCAGGCCTTACATACCTTGCTAGACTCCCCTTATGCTCGAGTCCATATTGCAGAAGATCAGCTGATAGGTGTT
GAGTTGCTGAGTGTTTTGCACCGCCTTCTATTGACCTGGAATCCATCATCTGTCCAGCTGTTGGTTACTGGAGTTGTACAACAGATAGTA
AGAGCTGCTCAGGATTATTTGCAAGAGAAAAGAAACACTCTAAATGAAGATGATATGGAAAAAGAGGCCTGTACCGTATTGGGAGAAGGA
GGTGACAGCGGTGGTCTCATTCCTGGAAAATCTCTTGTGTTTGCAACTATGGAGCTGCTGATGTTCATTTTAGTACGGCATATGCCACAT
CTCAGTACCAAGGTGTCAGACTCTCCAAGTCACATAGCCACTAAAACTCGACTATCAGAAGAAAGTGCTCGTTTGGTGGCAGCCACAGTT
ACCATACTCTCTGATTTACCATCCCTTTGTTCACCCGCTGGATGTATGACAATCCTGCCCACAATTCTGTTCTTAATTGCAAGAATATTG
AAAGACACAGCAATAAAGTCTGCAGATAATCAGGTTCCTCCACCAGTCAGTGCAGCTCTTCAAGGGATTAAAAGTATTGTGACACTTTCA
ATGGCCAAAACTGAGGCTGGCGTTCAAAAACAGTGGACAGCTCTGATTCGTAGCACGCTTGCTTGCATCCTGGAATATTCTCAACCAGAA
GACTCTGTACCTACACCTGATGAAGTAAGCATGCTAACAGCAATTGCACTCTTCCTGTGGTCTGCTAGTAATGAAATAATAGGAGTCCAG
TCATTACAGAATGGCTGCATGAACAGATTTAAAAATGCATTAAATTCATGCGACCCATGGGTTCAAGCCAAATGTTACCAGCTTCTCCTC
TCAGTCTTCCAGCATTCCAATCGTGCCCTTTCAACTCCTTATATTCATTCATTAGCTCCAATAGTGGTTGAAAAGCTAAAAGCTGTTGAA
AGAAACAGACCAGCCAGTAACATAGAGCTTTTAGCGGTTCAAGAAGGAATAAAAGTTCTTGAAACACTGGTTGCTCTTGGTGAAGAACAA
AACAGAGTCCAGCTACTTGCTCTTTTAGTTCCCACTTTGATATCTTACCTGCTGGATGAAAATTCTTTTGCCTCAGCAAGTTCAGCTTCC
AAAGATCTTCATGAGTTTGCACTCCAGAATTTAATGCATATTGGACCTCTGTATCCACATGCTTTCAAGACAGTAATGGGGGCTGCTCCT
GAGTTGAAAGTGCGTCTAGAAACTGCCGTTCGAGCAAGCCAAGCGAGCAAAGCTAAAGCGGCTGCCAGACAACCAGCCCCCGCCATACAT
TCTGCACCAACAATTAAGCTAAAAACAAGTTTTTTTTAATTTGTAATTTCATTTATTTGTATTTATGTTGTCAACTAGCCCCTAATTAGT
GATGGCCACTGTATCATTCCAGGCTACCTATGGGTTCTGTTTTATTTGTATATTGGTATTATAGTGCTTCCAAGTAGGTTAAGTGAAATA
ATGCTCACACCACTTATTGATTTTTAAGGAGTGATTTTTTTTATCATGTGGTGAATATGTTTTCATTTTCCTCCTAATAATGTTTCTCTT
TTGTTAACTTATTTATTTTTCAAACACTGAGCCATAGTCTTAAATTTAAATGCTAAAAACAATTGTATCATGTAGTCGGGCAGCCTATTG
ATACTGTCAGGGGAAAAAAATGGGTCAGAACTCAGCATCTGTCATGAAAAAAATCAATTGAAAAACAAGCAGATTTTAAATTTTGAAGTA
ATCAAAATAATGGAAAGTGTCTGTTTTGTGGTGTATATACTATGAATAAAATCACAGCATTTTCTAAGCATTTCCCAAAATGTCCTTATC
TTTCTGATGGATCTTTTAGCTTTCATATCAAATTACTAAATTATGCTATGTATATTTTAGTTGGTAACAATTAAAATTCTCATTTAAAGG

>87738_87738_5_STRN-HEATR5B_STRN_chr2_37121041_ENST00000263918_HEATR5B_chr2_37293053_ENST00000233099_length(amino acids)=1989AA_BP=310
MDEQAGPGVFFSNNHPGAGGAKGLGPLAEAAAAGDGAAAAGAARAQYSLPGILHFLQHEWARFEVERAQWEVERAELQAQIAFLQGERKG
QENLKKDLVRRIKMLEYALKQERAKYHKLKYGTELNQGDMKPPSYDSDEGNETEVQPQQNSQLMWKQGRQLLRQYLQEVGYTDTILDVKS
KRVRALLGFSSDVTDREDDKNQDSVVNGTEAEVKETAMIAKSELTDSASVLDNFKFLESAAADFSDEDEDDDVDGREKSVIDTSTIVRKK
ALPDSGEDRDTKEALKEFDFLVTSEEGDNESRSAGDGTDWEAVVNDTSGENKSGAADIAASQHVMVCALQELGSLVQSLNATASPLIQEA
SIGLLEIVTSVLLHPSMAARLAAAWCLRCVAVALPFQLTPFLDRCAERLNNLKTSPEAVSGYSFAMAALLGGVHQCPLGIPHAKGKMVVS
IAEDLLRTAAQNSRLSLQRTQAGWLLLGALMTLGPSVVRYHLPKMLLLWRNVFPRSLKELEAEKARGDSFTWQVTLEGRAGALCAMRSFV
AHCPELLTEDVIRKLMTPIECAMTMMSHIPSVMKAHGAHLKASAAMVRLRLYDILALLPPKTYEGSFNALLRELVAEFTLTDNSANTTTS
LLRSLCHYDDSVLLGSWLQETDHKSIEDQLQPNSASGSGALEHDPSSIYLRIPAGEAVPGPLPLGVSVIDASVALFGVVFPHVSYKHRLQ
MLDHFAECVKQAKGVRQQAVQLNIFTAVLSALKGLAENKSTLGPEEVRKSALTLVMGPLDNPNPILRCAAGEALGRMAQVVGEATFIARM
AQYSFDKLKSARDVVSRTGHSLALGCLHRYVGGIGSGQHLKTSVSILLALAQDGTSPEVQTWSLHSLALIVDSSGPMYRGYVEPTLSLVL
TLLLTVPPSHTEVHQCLGRCLGAIITTVGPELQGNGATTSTIRSSCLVGCAITQDHSDSLVQAAAISCLQQLHMFAPRHVNLSSLVPSLC
VHLCSSHLLLRRAAVACLRQLAQREAAEVCEYAMSLAKNTGDKESSSANVSPFAPGVSSRTDIHCRHQGVNITETGLEGLLFGMLDRETD
RKLCSDIHDTLGHMLSSLAVEKLSHWLMLCKDVLAASSDMSTATLLSSGKDEEAEKKDEMDDDTMFTTLGEEDKSKPFVAPRWATRVFAA
DCLCRIINLCENADQAHFDLALARSAKLRNPTNDLLVLHLSDLIRMAFMAATDHSNQLRMAGLQALEDIIKKFASVPEPEFPGHVILEQY
QANVGAALRPAFSQDTPSDIIAKACQVCSTWIGSGVVSDLNDLRRVHNLLVSSLDKVQAGKGSSSQLYRESATTMEKLAVLKAWAEVYVV
AMNIKKEAESKPKRAIKNTDDDDDDCGTIDELPPDSLITLVQPELPTLSRLWLAALKDYALLTLPAEFSSQLPPDGGAFYTPETIDTARL
HYRNSWAPILHAVALWLNSTGFTCSESTEAAAISGLQKRSTSVNLNQASGAVGSAKSLPEINKDRMHLILGVSIQFLCSPRPEEPIEHVT
ACLQALHTLLDSPYARVHIAEDQLIGVELLSVLHRLLLTWNPSSVQLLVTGVVQQIVRAAQDYLQEKRNTLNEDDMEKEACTVLGEGGDS
GGLIPGKSLVFATMELLMFILVRHMPHLSTKVSDSPSHIATKTRLSEESARLVAATVTILSDLPSLCSPAGCMTILPTILFLIARILKDT
AIKSADNQVPPPVSAALQGIKSIVTLSMAKTEAGVQKQWTALIRSTLACILEYSQPEDSVPTPDEVSMLTAIALFLWSASNEIIGVQSLQ
NGCMNRFKNALNSCDPWVQAKCYQLLLSVFQHSNRALSTPYIHSLAPIVVEKLKAVERNRPASNIELLAVQEGIKVLETLVALGEEQNRV
QLLALLVPTLISYLLDENSFASASSASKDLHEFALQNLMHIGPLYPHAFKTVMGAAPELKVRLETAVRASQASKAKAAARQPAPAIHSAP

--------------------------------------------------------------
>87738_87738_6_STRN-HEATR5B_STRN_chr2_37121041_ENST00000263918_HEATR5B_chr2_37293053_ENST00000354531_length(transcript)=6192nt_BP=940nt
GCGGCCGCCATGGACGAGCAGGCGGGTCCCGGCGTCTTCTTCAGCAACAACCACCCGGGCGCCGGCGGTGCCAAGGGGCTCGGGCCTCTG
GCGGAGGCTGCCGCGGCCGGCGACGGGGCGGCTGCGGCGGGGGCGGCCCGAGCCCAGTACAGTCTCCCGGGGATCCTGCACTTCCTGCAG
CACGAGTGGGCCCGCTTCGAGGTGGAGAGAGCCCAGTGGGAGGTGGAGCGGGCGGAGCTGCAGGCCCAGATTGCCTTCCTGCAGGGAGAA
AGGAAGGGCCAAGAAAATTTGAAGAAGGATCTTGTGAGGAGGATCAAAATGTTGGAGTATGCTCTTAAACAGGAAAGAGCCAAATACCAC
AAGTTGAAATACGGGACAGAATTGAATCAGGGAGATATGAAGCCTCCAAGCTATGATTCTGATGAAGGTAATGAAACAGAAGTGCAGCCA
CAACAAAACAGCCAGTTAATGTGGAAACAAGGTCGACAACTACTCAGACAGTATCTACAGGAGGTGGGTTATACAGATACTATTCTAGAT
GTGAAATCTAAACGAGTGCGAGCTTTGTTGGGCTTTTCAAGTGATGTCACGGACAGGGAAGATGACAAAAATCAGGACTCAGTTGTAAAT
GGCACAGAGGCTGAAGTTAAAGAGACAGCAATGATTGCAAAATCTGAGTTAACAGATTCTGCCTCCGTGCTGGATAATTTCAAATTCCTT
GAAAGTGCAGCTGCAGATTTCAGTGATGAAGATGAAGATGATGATGTTGATGGAAGAGAGAAAAGCGTCATTGATACTTCAACAATTGTT
AGGAAAAAAGCATTGCCTGACAGCGGTGAAGATCGAGATACAAAAGAAGCTCTAAAGGAGTTTGACTTCTTGGTTACATCAGAGGAAGGA
GACAATGAATCTAGAAGTGCAGGCGATGGAACAGACTGGGAAGCAGTAGTGAATGACACAAGTGGAGAAAACAAATCTGGCGCAGCAGAC
ATTGCAGCAAGCCAGCATGTGATGGTCTGTGCCCTCCAGGAACTCGGGAGCCTGGTGCAGAGCTTGAATGCCACCGCATCCCCTCTTATT
CAAGAAGCATCTATAGGGCTTTTGGAGATTGTGACTTCAGTGCTGCTTCATCCAAGCATGGCTGCCCGACTTGCTGCTGCATGGTGTTTG
CGCTGTGTGGCTGTGGCATTACCTTTCCAGCTGACACCATTTCTAGACAGGTGTGCAGAACGGCTCAACAACTTGAAGACCTCACCAGAA
GCTGTCAGTGGATATAGTTTTGCAATGGCTGCTTTGTTAGGTGGAGTACATCAGTGTCCTTTGGGCATTCCTCATGCCAAAGGAAAGATG
GTAGTTAGTATTGCTGAAGATCTTTTACGAACTGCTGCCCAAAATAGCAGGCTATCTTTACAGCGCACCCAAGCTGGCTGGCTTTTACTT
GGAGCACTTATGACTTTAGGACCATCTGTCGTTCGTTACCATCTGCCCAAGATGTTGTTATTGTGGCGAAATGTTTTCCCACGTTCCTTA
AAGGAATTGGAAGCTGAGAAGGCCCGAGGCGATTCTTTTACCTGGCAGGTAACTTTGGAAGGTCGTGCTGGAGCTCTATGTGCCATGAGG
AGCTTCGTTGCACATTGTCCTGAGCTACTAACTGAAGATGTGATTCGAAAATTGATGACCCCTATTGAATGTGCCATGACTATGATGTCA
CACATTCCATCTGTAATGAAAGCCCATGGAGCTCATCTGAAAGCTAGTGCTGCAATGGTCCGTTTAAGACTTTATGATATCTTGGCTTTG
TTACCTCCAAAAACTTATGAAGGATCTTTTAATGCACTTCTTAGAGAACTGGTAGCGGAATTCACTTTGACTGACAACTCAGCCAACACA
ACTACTTCCCTCCTCAGATCCCTCTGCCATTATGATGATAGTGTTCTTCTTGGTTCTTGGCTTCAGGAAACTGATCATAAATCAATTGAA
GACCAGCTCCAGCCAAACAGTGCCTCTGGAAGTGGGGCTCTGGAGCATGATCCTTCCTCTATTTATTTACGCATACCTGCTGGAGAAGCA
GTACCTGGTCCCCTCCCTCTCGGAGTCTCAGTCATTGATGCTTCTGTGGCCCTTTTTGGTGTAGTGTTTCCTCATGTTTCTTATAAACAC
CGATTACAAATGTTGGATCACTTTGCTGAATGTGTTAAACAAGCTAAAGGTGTCCGCCAGCAGGCTGTGCAGCTTAACATATTTACTGCT
GTTCTTAGTGCACTAAAGGGCTTAGCTGAAAACAAAAGTACTTTAGGACCTGAGGAAGTTCGTAAATCTGCCCTGACACTGGTTATGGGT
CCTCTGGACAACCCAAACCCCATCTTACGTTGTGCAGCGGGGGAAGCTCTTGGAAGAATGGCTCAGGTGGTTGGAGAAGCAACTTTTATT
GCTAGAATGGCCCAATATAGCTTTGACAAGTTGAAATCGGCTCGAGATGTTGTATCTAGGACTGGTCATTCATTGGCTCTTGGTTGTTTG
CATCGTTATGTTGGTGGAATAGGCTCAGGACAACATCTGAAGACCAGTGTCAGCATTTTATTGGCTCTAGCACAAGATGGGACATCCCCT
GAAGTCCAGACTTGGTCTCTTCATTCACTTGCTTTGATAGTGGATTCTAGTGGTCCGATGTATCGTGGCTATGTGGAACCAACATTATCT
CTAGTTCTTACCTTGCTGTTGACAGTTCCGCCTTCACATACAGAAGTTCATCAGTGTTTGGGTCGATGCTTGGGTGCTATAATAACTACT
GTTGGCCCTGAACTACAAGGGAATGGAGCAACAACTTCTACAATTCGTTCCTCTTGTTTGGTGGGTTGTGCAATAACACAAGACCATTCA
GATTCTCTTGTTCAGGCAGCTGCCATATCTTGCCTTCAGCAGCTTCACATGTTTGCACCACGACATGTCAATCTATCTAGCCTTGTTCCT
AGCCTTTGTGTTCACTTATGTAGTTCCCATTTGTTACTTCGACGAGCAGCTGTGGCATGTCTTCGGCAACTTGCACAAAGAGAAGCAGCG
GAAGTATGTGAATATGCCATGAGCCTGGCAAAAAATACAGGGGACAAAGAGAGCAGTAGTGCCAATGTCAGTCCTTTTGCCCCTGGGGTT
AGTTCTCGAACTGATATCCATTGCCGGCACCAAGGTGTTAATATAACAGAAACTGGTCTTGAGGGACTTCTTTTTGGAATGCTAGACCGG
GAGACAGATCGAAAATTATGTTCTGATATTCATGACACTTTGGGACATATGCTTTCTTCGCTGGCAGTAGAAAAACTTTCTCATTGGCTA
ATGCTTTGTAAAGATGTCCTGGCAGCTTCTAGTGATATGAGTACTGCAACTCTCTTAAGTAGTGGAAAAGATGAAGAAGCTGAAAAGAAA
GATGAGATGGATGATGATACCATGTTTACCACGTTAGGTGAAGAAGATAAATCAAAGCCCTTTGTGGCCCCTCGCTGGGCCACTCGAGTA
TTTGCTGCCGATTGCCTGTGTCGAATCATCAATTTGTGTGAGAATGCAGACCAGGCTCACTTTGATCTTGCCTTGGCACGTTCTGCTAAA
CTTCGAAACCCTACAAATGACCTCTTGGTACTTCATCTCTCTGACCTCATTCGCATGGCATTCATGGCTGCAACTGATCATAGCAACCAG
CTGCGAATGGCTGGGCTCCAGGCGCTTGAAGACATTATCAAGAAGTTTGCGTCTGTGCCTGAGCCAGAATTTCCAGGTCATGTGATACTG
GAGCAGTATCAGGCTAATGTGGGAGCTGCTCTAAGACCAGCCTTTTCACAAGATACACCATCAGATATAATAGCGAAAGCTTGCCAGGTA
TGTAGTACATGGATAGGAAGTGGAGTTGTCAGTGATCTCAATGATCTCCGTCGAGTACACAATCTTCTTGTTTCTTCTCTGGACAAAGTT
CAGGCTGGAAAAGGATCTTCCAGCCAGCTGTACCGAGAGAGTGCCACGACCATGGAAAAACTGGCTGTTCTCAAAGCTTGGGCAGAGGTA
TATGTGGTCGCTATGAATATTAAAAAGGAAGCAGAGTCAAAACCAAAAAGAGCAATTAAAAATACTGACGATGATGATGACGACTGTGGT
ACCATCGATGAACTGCCACCAGATAGTTTAATAACACTGGTACAACCTGAACTACCAACACTCAGTCGCCTGTGGTTAGCAGCATTAAAA
GATTATGCACTCTTGACTTTACCAGCCGAATTTTCTAGTCAGCTTCCTCCAGATGGTGGAGCATTTTATACCCCTGAAACTATTGATACA
GCTAGACTTCACTATCGGAATTCCTGGGCCCCAATTCTCCATGCGGTGGCACTTTGGTTAAATAGCACAGGATTTACGTGCTCAGAGTCT
ACAGAAGCAGCAGCAATATCTGGTTTACAAAAACGTTCTACATCTGTCAATTTAAACCAGGCATCAGGAGCAGTGGGTAGTGCTAAATCT
TTGCCAGAAATTAACAAAGACAGAATGCATCTGATTTTAGGTGTGAGTATACAGTTTCTTTGTTCCCCTAGACCTGAGGAGCCCATTGAA
CATGTTACAGCATGCCTGCAGGCCTTACATACCTTGCTAGACTCCCCTTATGCTCGAGTCCATATTGCAGAAGATCAGCTGATAGGTGTT
GAGTTGCTGAGTGTTTTGCACCGCCTTCTATTGACCTGGAATCCATCATCTGTCCAGCTGTTGGTTACTGGAGTTGTACAACAGATAGTA
AGAGCTGCTCAGGATTATTTGCAAGAGAAAAGAAACACTCTAAGATGTATGACAATCCTGCCCACAATTCTGTTCTTAATTGCAAGAATA
TTGAAAGACACAGCAATAAAGTCTGCAGATAATCAGGTTCCTCCACCAGTCAGTGCAGCTCTTCAAGGGATTAAAAGTATTGTGACACTT
TCAATGGCCAAAACTGAGGCTGGCGTTCAAAAACAGTGGACAGCTCTGATTCGTAGCACGCTTGCTTGCATCCTGGAATATTCTCAACCA
GAAGACTCTGTACCTACACCTGATGAAGTAAGCATGCTAACAGCAATTGCACTCTTCCTGTGGTCTGCTAGTAATGAAATAATAGGAGTC
CAGTCATTACAGAATGGCTGCATGAACAGATTTAAAAATGCATTAAATTCATGCGACCCATGGGTTCAAGCCAAATGTTACCAGCTTCTC
CTCTCAGTCTTCCAGCATTCCAATCGTGCCCTTTCAACTCCTTATATTCATTCATTAGCTCCAATAGTGGTTGAAAAGCTAAAAGCTGTT
GAAAGAAACAGACCAGCCAGTAACATAGAGCTTTTAGCGGTTCAAGAAGGAATAAAAGTTCTTGAAACACTGGTTGCTCTTGGTGAAGAA
CAAAACAGAGTCCAGCTACTTGCTCTTTTAGTTCCCACTTTGATATCTTACCTGCTGGATGAAAATTCTTTTGCCTCAGCAAGTTCAGCT
TCCAAAGATCTTCATGAGTTTGCACTCCAGAATTTAATGCATATTGGACCTCTGTATCCACATGCTTTCAAGACAGTAATGGGGGCTGCT
CCTGAGTTGAAAGTGCGTCTAGAAACTGCCGTTCGAGCAAGCCAAGCGAGCAAAGCTAAAGCGGCTGCCAGACAACCAGCCCCCGCCATA
CATTCTGCACCAACAATTAAGCTAAAAACAAGTTTTTTTTAATTTGTAATTTCATTTATTTGTATTTATGTTGTCAACTAGCCCCTAATT
AGTGATGGCCACTGTATCATTCCAGGCTACCTATGGGTTCTGTTTTATTTGTATATTGGTATTATAGTGCTTCCAAGTAGGTTAAGTGAA
ATAATGCTCACACCACTTATTGATTTTTAAGGAGTGATTTTTTTTATCATGTGGTGAATATGTTTTCATTTTCCTCCTAATAATGTTTCT
CTTTTGTTAACTTATTTATTTTTCAAACACTGAGCCATAGTCTTAAATTTAAATGCTAAAAACAATTGTATCATGTAGTCGGGCAGCCTA
TTGATACTGTCAGGGGAAAAAAATGGGTCAGAACTCAGCATCTGTCATGAAAAAAATCAATTGAAAAACAAGCAGATTTTAAATTTTGAA

>87738_87738_6_STRN-HEATR5B_STRN_chr2_37121041_ENST00000263918_HEATR5B_chr2_37293053_ENST00000354531_length(amino acids)=1900AA_BP=310
MDEQAGPGVFFSNNHPGAGGAKGLGPLAEAAAAGDGAAAAGAARAQYSLPGILHFLQHEWARFEVERAQWEVERAELQAQIAFLQGERKG
QENLKKDLVRRIKMLEYALKQERAKYHKLKYGTELNQGDMKPPSYDSDEGNETEVQPQQNSQLMWKQGRQLLRQYLQEVGYTDTILDVKS
KRVRALLGFSSDVTDREDDKNQDSVVNGTEAEVKETAMIAKSELTDSASVLDNFKFLESAAADFSDEDEDDDVDGREKSVIDTSTIVRKK
ALPDSGEDRDTKEALKEFDFLVTSEEGDNESRSAGDGTDWEAVVNDTSGENKSGAADIAASQHVMVCALQELGSLVQSLNATASPLIQEA
SIGLLEIVTSVLLHPSMAARLAAAWCLRCVAVALPFQLTPFLDRCAERLNNLKTSPEAVSGYSFAMAALLGGVHQCPLGIPHAKGKMVVS
IAEDLLRTAAQNSRLSLQRTQAGWLLLGALMTLGPSVVRYHLPKMLLLWRNVFPRSLKELEAEKARGDSFTWQVTLEGRAGALCAMRSFV
AHCPELLTEDVIRKLMTPIECAMTMMSHIPSVMKAHGAHLKASAAMVRLRLYDILALLPPKTYEGSFNALLRELVAEFTLTDNSANTTTS
LLRSLCHYDDSVLLGSWLQETDHKSIEDQLQPNSASGSGALEHDPSSIYLRIPAGEAVPGPLPLGVSVIDASVALFGVVFPHVSYKHRLQ
MLDHFAECVKQAKGVRQQAVQLNIFTAVLSALKGLAENKSTLGPEEVRKSALTLVMGPLDNPNPILRCAAGEALGRMAQVVGEATFIARM
AQYSFDKLKSARDVVSRTGHSLALGCLHRYVGGIGSGQHLKTSVSILLALAQDGTSPEVQTWSLHSLALIVDSSGPMYRGYVEPTLSLVL
TLLLTVPPSHTEVHQCLGRCLGAIITTVGPELQGNGATTSTIRSSCLVGCAITQDHSDSLVQAAAISCLQQLHMFAPRHVNLSSLVPSLC
VHLCSSHLLLRRAAVACLRQLAQREAAEVCEYAMSLAKNTGDKESSSANVSPFAPGVSSRTDIHCRHQGVNITETGLEGLLFGMLDRETD
RKLCSDIHDTLGHMLSSLAVEKLSHWLMLCKDVLAASSDMSTATLLSSGKDEEAEKKDEMDDDTMFTTLGEEDKSKPFVAPRWATRVFAA
DCLCRIINLCENADQAHFDLALARSAKLRNPTNDLLVLHLSDLIRMAFMAATDHSNQLRMAGLQALEDIIKKFASVPEPEFPGHVILEQY
QANVGAALRPAFSQDTPSDIIAKACQVCSTWIGSGVVSDLNDLRRVHNLLVSSLDKVQAGKGSSSQLYRESATTMEKLAVLKAWAEVYVV
AMNIKKEAESKPKRAIKNTDDDDDDCGTIDELPPDSLITLVQPELPTLSRLWLAALKDYALLTLPAEFSSQLPPDGGAFYTPETIDTARL
HYRNSWAPILHAVALWLNSTGFTCSESTEAAAISGLQKRSTSVNLNQASGAVGSAKSLPEINKDRMHLILGVSIQFLCSPRPEEPIEHVT
ACLQALHTLLDSPYARVHIAEDQLIGVELLSVLHRLLLTWNPSSVQLLVTGVVQQIVRAAQDYLQEKRNTLRCMTILPTILFLIARILKD
TAIKSADNQVPPPVSAALQGIKSIVTLSMAKTEAGVQKQWTALIRSTLACILEYSQPEDSVPTPDEVSMLTAIALFLWSASNEIIGVQSL
QNGCMNRFKNALNSCDPWVQAKCYQLLLSVFQHSNRALSTPYIHSLAPIVVEKLKAVERNRPASNIELLAVQEGIKVLETLVALGEEQNR
VQLLALLVPTLISYLLDENSFASASSASKDLHEFALQNLMHIGPLYPHAFKTVMGAAPELKVRLETAVRASQASKAKAAARQPAPAIHSA

--------------------------------------------------------------
>87738_87738_7_STRN-HEATR5B_STRN_chr2_37121041_ENST00000379213_HEATR5B_chr2_37293053_ENST00000233099_length(transcript)=6527nt_BP=895nt
ATGGACGAGCAGGCGGGTCCCGGCGTCTTCTTCAGCAACAACCACCCGGGCGCCGGCGGTGCCAAGGGGCTCGGGCCTCTGGCGGGGGCG
GCCCGAGCCCAGTACAGTCTCCCGGGGATCCTGCACTTCCTGCAGCACGAGTGGGCCCGCTTCGAGGTGGAGAGAGCCCAGTGGGAGGTG
GAGCGGGCGGAGCTGCAGGCCCAGATTGCCTTCCTGCAGGGAGAAAGGAAGGGCCAAGAAAATTTGAAGAAGGATCTTGTGAGGAGGATC
AAAATGTTGGAGTATGCTCTTAAACAGGAAAGAGCCAAATACCACAAGTTGAAATACGGGACAGAATTGAATCAGGGAGATATGAAGCCT
CCAAGCTATGATTCTGATGAAGGTAATGAAACAGAAGTGCAGCCACAACAAAACAGCCAGTTAATGTGGAAACAAGGTCGACAACTACTC
AGACAGTATCTACAGGAGGTGGGTTATACAGATACTATTCTAGATGTGAAATCTAAACGAGTGCGAGCTTTGTTGGGCTTTTCAAGTGAT
GTCACGGACAGGGAAGATGACAAAAATCAGGACTCAGTTGTAAATGGCACAGAGGCTGAAGTTAAAGAGACAGCAATGATTGCAAAATCT
GAGTTAACAGATTCTGCCTCCGTGCTGGATAATTTCAAATTCCTTGAAAGTGCAGCTGCAGATTTCAGTGATGAAGATGAAGATGATGAT
GTTGATGGAAGAGAGAAAAGCGTCATTGATACTTCAACAATTGTTAGGAAAAAAGCATTGCCTGACAGCGGTGAAGATCGAGATACAAAA
GAAGCTCTAAAGGAGTTTGACTTCTTGGTTACATCAGAGGAAGGAGACAATGAATCTAGAAGTGCAGGCGATGGAACAGACTGGGAAGCA
GTAGTGAATGACACAAGTGGAGAAAACAAATCTGGCGCAGCAGACATTGCAGCAAGCCAGCATGTGATGGTCTGTGCCCTCCAGGAACTC
GGGAGCCTGGTGCAGAGCTTGAATGCCACCGCATCCCCTCTTATTCAAGAAGCATCTATAGGGCTTTTGGAGATTGTGACTTCAGTGCTG
CTTCATCCAAGCATGGCTGCCCGACTTGCTGCTGCATGGTGTTTGCGCTGTGTGGCTGTGGCATTACCTTTCCAGCTGACACCATTTCTA
GACAGGTGTGCAGAACGGCTCAACAACTTGAAGACCTCACCAGAAGCTGTCAGTGGATATAGTTTTGCAATGGCTGCTTTGTTAGGTGGA
GTACATCAGTGTCCTTTGGGCATTCCTCATGCCAAAGGAAAGATGGTAGTTAGTATTGCTGAAGATCTTTTACGAACTGCTGCCCAAAAT
AGCAGGCTATCTTTACAGCGCACCCAAGCTGGCTGGCTTTTACTTGGAGCACTTATGACTTTAGGACCATCTGTCGTTCGTTACCATCTG
CCCAAGATGTTGTTATTGTGGCGAAATGTTTTCCCACGTTCCTTAAAGGAATTGGAAGCTGAGAAGGCCCGAGGCGATTCTTTTACCTGG
CAGGTAACTTTGGAAGGTCGTGCTGGAGCTCTATGTGCCATGAGGAGCTTCGTTGCACATTGTCCTGAGCTACTAACTGAAGATGTGATT
CGAAAATTGATGACCCCTATTGAATGTGCCATGACTATGATGTCACACATTCCATCTGTAATGAAAGCCCATGGAGCTCATCTGAAAGCT
AGTGCTGCAATGGTCCGTTTAAGACTTTATGATATCTTGGCTTTGTTACCTCCAAAAACTTATGAAGGATCTTTTAATGCACTTCTTAGA
GAACTGGTAGCGGAATTCACTTTGACTGACAACTCAGCCAACACAACTACTTCCCTCCTCAGATCCCTCTGCCATTATGATGATAGTGTT
CTTCTTGGTTCTTGGCTTCAGGAAACTGATCATAAATCAATTGAAGACCAGCTCCAGCCAAACAGTGCCTCTGGAAGTGGGGCTCTGGAG
CATGATCCTTCCTCTATTTATTTACGCATACCTGCTGGAGAAGCAGTACCTGGTCCCCTCCCTCTCGGAGTCTCAGTCATTGATGCTTCT
GTGGCCCTTTTTGGTGTAGTGTTTCCTCATGTTTCTTATAAACACCGATTACAAATGTTGGATCACTTTGCTGAATGTGTTAAACAAGCT
AAAGGTGTCCGCCAGCAGGCTGTGCAGCTTAACATATTTACTGCTGTTCTTAGTGCACTAAAGGGCTTAGCTGAAAACAAAAGTACTTTA
GGACCTGAGGAAGTTCGTAAATCTGCCCTGACACTGGTTATGGGTCCTCTGGACAACCCAAACCCCATCTTACGTTGTGCAGCGGGGGAA
GCTCTTGGAAGAATGGCTCAGGTGGTTGGAGAAGCAACTTTTATTGCTAGAATGGCCCAATATAGCTTTGACAAGTTGAAATCGGCTCGA
GATGTTGTATCTAGGACTGGTCATTCATTGGCTCTTGGTTGTTTGCATCGTTATGTTGGTGGAATAGGCTCAGGACAACATCTGAAGACC
AGTGTCAGCATTTTATTGGCTCTAGCACAAGATGGGACATCCCCTGAAGTCCAGACTTGGTCTCTTCATTCACTTGCTTTGATAGTGGAT
TCTAGTGGTCCGATGTATCGTGGCTATGTGGAACCAACATTATCTCTAGTTCTTACCTTGCTGTTGACAGTTCCGCCTTCACATACAGAA
GTTCATCAGTGTTTGGGTCGATGCTTGGGTGCTATAATAACTACTGTTGGCCCTGAACTACAAGGGAATGGAGCAACAACTTCTACAATT
CGTTCCTCTTGTTTGGTGGGTTGTGCAATAACACAAGACCATTCAGATTCTCTTGTTCAGGCAGCTGCCATATCTTGCCTTCAGCAGCTT
CACATGTTTGCACCACGACATGTCAATCTATCTAGCCTTGTTCCTAGCCTTTGTGTTCACTTATGTAGTTCCCATTTGTTACTTCGACGA
GCAGCTGTGGCATGTCTTCGGCAACTTGCACAAAGAGAAGCAGCGGAAGTATGTGAATATGCCATGAGCCTGGCAAAAAATACAGGGGAC
AAAGAGAGCAGTAGTGCCAATGTCAGTCCTTTTGCCCCTGGGGTTAGTTCTCGAACTGATATCCATTGCCGGCACCAAGGTGTTAATATA
ACAGAAACTGGTCTTGAGGGACTTCTTTTTGGAATGCTAGACCGGGAGACAGATCGAAAATTATGTTCTGATATTCATGACACTTTGGGA
CATATGCTTTCTTCGCTGGCAGTAGAAAAACTTTCTCATTGGCTAATGCTTTGTAAAGATGTCCTGGCAGCTTCTAGTGATATGAGTACT
GCAACTCTCTTAAGTAGTGGAAAAGATGAAGAAGCTGAAAAGAAAGATGAGATGGATGATGATACCATGTTTACCACGTTAGGTGAAGAA
GATAAATCAAAGCCCTTTGTGGCCCCTCGCTGGGCCACTCGAGTATTTGCTGCCGATTGCCTGTGTCGAATCATCAATTTGTGTGAGAAT
GCAGACCAGGCTCACTTTGATCTTGCCTTGGCACGTTCTGCTAAACTTCGAAACCCTACAAATGACCTCTTGGTACTTCATCTCTCTGAC
CTCATTCGCATGGCATTCATGGCTGCAACTGATCATAGCAACCAGCTGCGAATGGCTGGGCTCCAGGCGCTTGAAGACATTATCAAGAAG
TTTGCGTCTGTGCCTGAGCCAGAATTTCCAGGTCATGTGATACTGGAGCAGTATCAGGCTAATGTGGGAGCTGCTCTAAGACCAGCCTTT
TCACAAGATACACCATCAGATATAATAGCGAAAGCTTGCCAGGTATGTAGTACATGGATAGGAAGTGGAGTTGTCAGTGATCTCAATGAT
CTCCGTCGAGTACACAATCTTCTTGTTTCTTCTCTGGACAAAGTTCAGGCTGGAAAAGGATCTTCCAGCCAGCTGTACCGAGAGAGTGCC
ACGACCATGGAAAAACTGGCTGTTCTCAAAGCTTGGGCAGAGGTATATGTGGTCGCTATGAATATTAAAAAGGAAGCAGAGTCAAAACCA
AAAAGAGCAATTAAAAATACTGACGATGATGATGACGACTGTGGTACCATCGATGAACTGCCACCAGATAGTTTAATAACACTGGTACAA
CCTGAACTACCAACACTCAGTCGCCTGTGGTTAGCAGCATTAAAAGATTATGCACTCTTGACTTTACCAGCCGAATTTTCTAGTCAGCTT
CCTCCAGATGGTGGAGCATTTTATACCCCTGAAACTATTGATACAGCTAGACTTCACTATCGGAATTCCTGGGCCCCAATTCTCCATGCG
GTGGCACTTTGGTTAAATAGCACAGGATTTACGTGCTCAGAGTCTACAGAAGCAGCAGCAATATCTGGTTTACAAAAACGTTCTACATCT
GTCAATTTAAACCAGGCATCAGGAGCAGTGGGTAGTGCTAAATCTTTGCCAGAAATTAACAAAGACAGAATGCATCTGATTTTAGGTGTG
AGTATACAGTTTCTTTGTTCCCCTAGACCTGAGGAGCCCATTGAACATGTTACAGCATGCCTGCAGGCCTTACATACCTTGCTAGACTCC
CCTTATGCTCGAGTCCATATTGCAGAAGATCAGCTGATAGGTGTTGAGTTGCTGAGTGTTTTGCACCGCCTTCTATTGACCTGGAATCCA
TCATCTGTCCAGCTGTTGGTTACTGGAGTTGTACAACAGATAGTAAGAGCTGCTCAGGATTATTTGCAAGAGAAAAGAAACACTCTAAAT
GAAGATGATATGGAAAAAGAGGCCTGTACCGTATTGGGAGAAGGAGGTGACAGCGGTGGTCTCATTCCTGGAAAATCTCTTGTGTTTGCA
ACTATGGAGCTGCTGATGTTCATTTTAGTACGGCATATGCCACATCTCAGTACCAAGGTGTCAGACTCTCCAAGTCACATAGCCACTAAA
ACTCGACTATCAGAAGAAAGTGCTCGTTTGGTGGCAGCCACAGTTACCATACTCTCTGATTTACCATCCCTTTGTTCACCCGCTGGATGT
ATGACAATCCTGCCCACAATTCTGTTCTTAATTGCAAGAATATTGAAAGACACAGCAATAAAGTCTGCAGATAATCAGGTTCCTCCACCA
GTCAGTGCAGCTCTTCAAGGGATTAAAAGTATTGTGACACTTTCAATGGCCAAAACTGAGGCTGGCGTTCAAAAACAGTGGACAGCTCTG
ATTCGTAGCACGCTTGCTTGCATCCTGGAATATTCTCAACCAGAAGACTCTGTACCTACACCTGATGAAGTAAGCATGCTAACAGCAATT
GCACTCTTCCTGTGGTCTGCTAGTAATGAAATAATAGGAGTCCAGTCATTACAGAATGGCTGCATGAACAGATTTAAAAATGCATTAAAT
TCATGCGACCCATGGGTTCAAGCCAAATGTTACCAGCTTCTCCTCTCAGTCTTCCAGCATTCCAATCGTGCCCTTTCAACTCCTTATATT
CATTCATTAGCTCCAATAGTGGTTGAAAAGCTAAAAGCTGTTGAAAGAAACAGACCAGCCAGTAACATAGAGCTTTTAGCGGTTCAAGAA
GGAATAAAAGTTCTTGAAACACTGGTTGCTCTTGGTGAAGAACAAAACAGAGTCCAGCTACTTGCTCTTTTAGTTCCCACTTTGATATCT
TACCTGCTGGATGAAAATTCTTTTGCCTCAGCAAGTTCAGCTTCCAAAGATCTTCATGAGTTTGCACTCCAGAATTTAATGCATATTGGA
CCTCTGTATCCACATGCTTTCAAGACAGTAATGGGGGCTGCTCCTGAGTTGAAAGTGCGTCTAGAAACTGCCGTTCGAGCAAGCCAAGCG
AGCAAAGCTAAAGCGGCTGCCAGACAACCAGCCCCCGCCATACATTCTGCACCAACAATTAAGCTAAAAACAAGTTTTTTTTAATTTGTA
ATTTCATTTATTTGTATTTATGTTGTCAACTAGCCCCTAATTAGTGATGGCCACTGTATCATTCCAGGCTACCTATGGGTTCTGTTTTAT
TTGTATATTGGTATTATAGTGCTTCCAAGTAGGTTAAGTGAAATAATGCTCACACCACTTATTGATTTTTAAGGAGTGATTTTTTTTATC
ATGTGGTGAATATGTTTTCATTTTCCTCCTAATAATGTTTCTCTTTTGTTAACTTATTTATTTTTCAAACACTGAGCCATAGTCTTAAAT
TTAAATGCTAAAAACAATTGTATCATGTAGTCGGGCAGCCTATTGATACTGTCAGGGGAAAAAAATGGGTCAGAACTCAGCATCTGTCAT
GAAAAAAATCAATTGAAAAACAAGCAGATTTTAAATTTTGAAGTAATCAAAATAATGGAAAGTGTCTGTTTTGTGGTGTATATACTATGA
ATAAAATCACAGCATTTTCTAAGCATTTCCCAAAATGTCCTTATCTTTCTGATGGATCTTTTAGCTTTCATATCAAATTACTAAATTATG

>87738_87738_7_STRN-HEATR5B_STRN_chr2_37121041_ENST00000379213_HEATR5B_chr2_37293053_ENST00000233099_length(amino acids)=1977AA_BP=298
MDEQAGPGVFFSNNHPGAGGAKGLGPLAGAARAQYSLPGILHFLQHEWARFEVERAQWEVERAELQAQIAFLQGERKGQENLKKDLVRRI
KMLEYALKQERAKYHKLKYGTELNQGDMKPPSYDSDEGNETEVQPQQNSQLMWKQGRQLLRQYLQEVGYTDTILDVKSKRVRALLGFSSD
VTDREDDKNQDSVVNGTEAEVKETAMIAKSELTDSASVLDNFKFLESAAADFSDEDEDDDVDGREKSVIDTSTIVRKKALPDSGEDRDTK
EALKEFDFLVTSEEGDNESRSAGDGTDWEAVVNDTSGENKSGAADIAASQHVMVCALQELGSLVQSLNATASPLIQEASIGLLEIVTSVL
LHPSMAARLAAAWCLRCVAVALPFQLTPFLDRCAERLNNLKTSPEAVSGYSFAMAALLGGVHQCPLGIPHAKGKMVVSIAEDLLRTAAQN
SRLSLQRTQAGWLLLGALMTLGPSVVRYHLPKMLLLWRNVFPRSLKELEAEKARGDSFTWQVTLEGRAGALCAMRSFVAHCPELLTEDVI
RKLMTPIECAMTMMSHIPSVMKAHGAHLKASAAMVRLRLYDILALLPPKTYEGSFNALLRELVAEFTLTDNSANTTTSLLRSLCHYDDSV
LLGSWLQETDHKSIEDQLQPNSASGSGALEHDPSSIYLRIPAGEAVPGPLPLGVSVIDASVALFGVVFPHVSYKHRLQMLDHFAECVKQA
KGVRQQAVQLNIFTAVLSALKGLAENKSTLGPEEVRKSALTLVMGPLDNPNPILRCAAGEALGRMAQVVGEATFIARMAQYSFDKLKSAR
DVVSRTGHSLALGCLHRYVGGIGSGQHLKTSVSILLALAQDGTSPEVQTWSLHSLALIVDSSGPMYRGYVEPTLSLVLTLLLTVPPSHTE
VHQCLGRCLGAIITTVGPELQGNGATTSTIRSSCLVGCAITQDHSDSLVQAAAISCLQQLHMFAPRHVNLSSLVPSLCVHLCSSHLLLRR
AAVACLRQLAQREAAEVCEYAMSLAKNTGDKESSSANVSPFAPGVSSRTDIHCRHQGVNITETGLEGLLFGMLDRETDRKLCSDIHDTLG
HMLSSLAVEKLSHWLMLCKDVLAASSDMSTATLLSSGKDEEAEKKDEMDDDTMFTTLGEEDKSKPFVAPRWATRVFAADCLCRIINLCEN
ADQAHFDLALARSAKLRNPTNDLLVLHLSDLIRMAFMAATDHSNQLRMAGLQALEDIIKKFASVPEPEFPGHVILEQYQANVGAALRPAF
SQDTPSDIIAKACQVCSTWIGSGVVSDLNDLRRVHNLLVSSLDKVQAGKGSSSQLYRESATTMEKLAVLKAWAEVYVVAMNIKKEAESKP
KRAIKNTDDDDDDCGTIDELPPDSLITLVQPELPTLSRLWLAALKDYALLTLPAEFSSQLPPDGGAFYTPETIDTARLHYRNSWAPILHA
VALWLNSTGFTCSESTEAAAISGLQKRSTSVNLNQASGAVGSAKSLPEINKDRMHLILGVSIQFLCSPRPEEPIEHVTACLQALHTLLDS
PYARVHIAEDQLIGVELLSVLHRLLLTWNPSSVQLLVTGVVQQIVRAAQDYLQEKRNTLNEDDMEKEACTVLGEGGDSGGLIPGKSLVFA
TMELLMFILVRHMPHLSTKVSDSPSHIATKTRLSEESARLVAATVTILSDLPSLCSPAGCMTILPTILFLIARILKDTAIKSADNQVPPP
VSAALQGIKSIVTLSMAKTEAGVQKQWTALIRSTLACILEYSQPEDSVPTPDEVSMLTAIALFLWSASNEIIGVQSLQNGCMNRFKNALN
SCDPWVQAKCYQLLLSVFQHSNRALSTPYIHSLAPIVVEKLKAVERNRPASNIELLAVQEGIKVLETLVALGEEQNRVQLLALLVPTLIS

--------------------------------------------------------------
>87738_87738_8_STRN-HEATR5B_STRN_chr2_37121041_ENST00000379213_HEATR5B_chr2_37293053_ENST00000354531_length(transcript)=6147nt_BP=895nt
ATGGACGAGCAGGCGGGTCCCGGCGTCTTCTTCAGCAACAACCACCCGGGCGCCGGCGGTGCCAAGGGGCTCGGGCCTCTGGCGGGGGCG
GCCCGAGCCCAGTACAGTCTCCCGGGGATCCTGCACTTCCTGCAGCACGAGTGGGCCCGCTTCGAGGTGGAGAGAGCCCAGTGGGAGGTG
GAGCGGGCGGAGCTGCAGGCCCAGATTGCCTTCCTGCAGGGAGAAAGGAAGGGCCAAGAAAATTTGAAGAAGGATCTTGTGAGGAGGATC
AAAATGTTGGAGTATGCTCTTAAACAGGAAAGAGCCAAATACCACAAGTTGAAATACGGGACAGAATTGAATCAGGGAGATATGAAGCCT
CCAAGCTATGATTCTGATGAAGGTAATGAAACAGAAGTGCAGCCACAACAAAACAGCCAGTTAATGTGGAAACAAGGTCGACAACTACTC
AGACAGTATCTACAGGAGGTGGGTTATACAGATACTATTCTAGATGTGAAATCTAAACGAGTGCGAGCTTTGTTGGGCTTTTCAAGTGAT
GTCACGGACAGGGAAGATGACAAAAATCAGGACTCAGTTGTAAATGGCACAGAGGCTGAAGTTAAAGAGACAGCAATGATTGCAAAATCT
GAGTTAACAGATTCTGCCTCCGTGCTGGATAATTTCAAATTCCTTGAAAGTGCAGCTGCAGATTTCAGTGATGAAGATGAAGATGATGAT
GTTGATGGAAGAGAGAAAAGCGTCATTGATACTTCAACAATTGTTAGGAAAAAAGCATTGCCTGACAGCGGTGAAGATCGAGATACAAAA
GAAGCTCTAAAGGAGTTTGACTTCTTGGTTACATCAGAGGAAGGAGACAATGAATCTAGAAGTGCAGGCGATGGAACAGACTGGGAAGCA
GTAGTGAATGACACAAGTGGAGAAAACAAATCTGGCGCAGCAGACATTGCAGCAAGCCAGCATGTGATGGTCTGTGCCCTCCAGGAACTC
GGGAGCCTGGTGCAGAGCTTGAATGCCACCGCATCCCCTCTTATTCAAGAAGCATCTATAGGGCTTTTGGAGATTGTGACTTCAGTGCTG
CTTCATCCAAGCATGGCTGCCCGACTTGCTGCTGCATGGTGTTTGCGCTGTGTGGCTGTGGCATTACCTTTCCAGCTGACACCATTTCTA
GACAGGTGTGCAGAACGGCTCAACAACTTGAAGACCTCACCAGAAGCTGTCAGTGGATATAGTTTTGCAATGGCTGCTTTGTTAGGTGGA
GTACATCAGTGTCCTTTGGGCATTCCTCATGCCAAAGGAAAGATGGTAGTTAGTATTGCTGAAGATCTTTTACGAACTGCTGCCCAAAAT
AGCAGGCTATCTTTACAGCGCACCCAAGCTGGCTGGCTTTTACTTGGAGCACTTATGACTTTAGGACCATCTGTCGTTCGTTACCATCTG
CCCAAGATGTTGTTATTGTGGCGAAATGTTTTCCCACGTTCCTTAAAGGAATTGGAAGCTGAGAAGGCCCGAGGCGATTCTTTTACCTGG
CAGGTAACTTTGGAAGGTCGTGCTGGAGCTCTATGTGCCATGAGGAGCTTCGTTGCACATTGTCCTGAGCTACTAACTGAAGATGTGATT
CGAAAATTGATGACCCCTATTGAATGTGCCATGACTATGATGTCACACATTCCATCTGTAATGAAAGCCCATGGAGCTCATCTGAAAGCT
AGTGCTGCAATGGTCCGTTTAAGACTTTATGATATCTTGGCTTTGTTACCTCCAAAAACTTATGAAGGATCTTTTAATGCACTTCTTAGA
GAACTGGTAGCGGAATTCACTTTGACTGACAACTCAGCCAACACAACTACTTCCCTCCTCAGATCCCTCTGCCATTATGATGATAGTGTT
CTTCTTGGTTCTTGGCTTCAGGAAACTGATCATAAATCAATTGAAGACCAGCTCCAGCCAAACAGTGCCTCTGGAAGTGGGGCTCTGGAG
CATGATCCTTCCTCTATTTATTTACGCATACCTGCTGGAGAAGCAGTACCTGGTCCCCTCCCTCTCGGAGTCTCAGTCATTGATGCTTCT
GTGGCCCTTTTTGGTGTAGTGTTTCCTCATGTTTCTTATAAACACCGATTACAAATGTTGGATCACTTTGCTGAATGTGTTAAACAAGCT
AAAGGTGTCCGCCAGCAGGCTGTGCAGCTTAACATATTTACTGCTGTTCTTAGTGCACTAAAGGGCTTAGCTGAAAACAAAAGTACTTTA
GGACCTGAGGAAGTTCGTAAATCTGCCCTGACACTGGTTATGGGTCCTCTGGACAACCCAAACCCCATCTTACGTTGTGCAGCGGGGGAA
GCTCTTGGAAGAATGGCTCAGGTGGTTGGAGAAGCAACTTTTATTGCTAGAATGGCCCAATATAGCTTTGACAAGTTGAAATCGGCTCGA
GATGTTGTATCTAGGACTGGTCATTCATTGGCTCTTGGTTGTTTGCATCGTTATGTTGGTGGAATAGGCTCAGGACAACATCTGAAGACC
AGTGTCAGCATTTTATTGGCTCTAGCACAAGATGGGACATCCCCTGAAGTCCAGACTTGGTCTCTTCATTCACTTGCTTTGATAGTGGAT
TCTAGTGGTCCGATGTATCGTGGCTATGTGGAACCAACATTATCTCTAGTTCTTACCTTGCTGTTGACAGTTCCGCCTTCACATACAGAA
GTTCATCAGTGTTTGGGTCGATGCTTGGGTGCTATAATAACTACTGTTGGCCCTGAACTACAAGGGAATGGAGCAACAACTTCTACAATT
CGTTCCTCTTGTTTGGTGGGTTGTGCAATAACACAAGACCATTCAGATTCTCTTGTTCAGGCAGCTGCCATATCTTGCCTTCAGCAGCTT
CACATGTTTGCACCACGACATGTCAATCTATCTAGCCTTGTTCCTAGCCTTTGTGTTCACTTATGTAGTTCCCATTTGTTACTTCGACGA
GCAGCTGTGGCATGTCTTCGGCAACTTGCACAAAGAGAAGCAGCGGAAGTATGTGAATATGCCATGAGCCTGGCAAAAAATACAGGGGAC
AAAGAGAGCAGTAGTGCCAATGTCAGTCCTTTTGCCCCTGGGGTTAGTTCTCGAACTGATATCCATTGCCGGCACCAAGGTGTTAATATA
ACAGAAACTGGTCTTGAGGGACTTCTTTTTGGAATGCTAGACCGGGAGACAGATCGAAAATTATGTTCTGATATTCATGACACTTTGGGA
CATATGCTTTCTTCGCTGGCAGTAGAAAAACTTTCTCATTGGCTAATGCTTTGTAAAGATGTCCTGGCAGCTTCTAGTGATATGAGTACT
GCAACTCTCTTAAGTAGTGGAAAAGATGAAGAAGCTGAAAAGAAAGATGAGATGGATGATGATACCATGTTTACCACGTTAGGTGAAGAA
GATAAATCAAAGCCCTTTGTGGCCCCTCGCTGGGCCACTCGAGTATTTGCTGCCGATTGCCTGTGTCGAATCATCAATTTGTGTGAGAAT
GCAGACCAGGCTCACTTTGATCTTGCCTTGGCACGTTCTGCTAAACTTCGAAACCCTACAAATGACCTCTTGGTACTTCATCTCTCTGAC
CTCATTCGCATGGCATTCATGGCTGCAACTGATCATAGCAACCAGCTGCGAATGGCTGGGCTCCAGGCGCTTGAAGACATTATCAAGAAG
TTTGCGTCTGTGCCTGAGCCAGAATTTCCAGGTCATGTGATACTGGAGCAGTATCAGGCTAATGTGGGAGCTGCTCTAAGACCAGCCTTT
TCACAAGATACACCATCAGATATAATAGCGAAAGCTTGCCAGGTATGTAGTACATGGATAGGAAGTGGAGTTGTCAGTGATCTCAATGAT
CTCCGTCGAGTACACAATCTTCTTGTTTCTTCTCTGGACAAAGTTCAGGCTGGAAAAGGATCTTCCAGCCAGCTGTACCGAGAGAGTGCC
ACGACCATGGAAAAACTGGCTGTTCTCAAAGCTTGGGCAGAGGTATATGTGGTCGCTATGAATATTAAAAAGGAAGCAGAGTCAAAACCA
AAAAGAGCAATTAAAAATACTGACGATGATGATGACGACTGTGGTACCATCGATGAACTGCCACCAGATAGTTTAATAACACTGGTACAA
CCTGAACTACCAACACTCAGTCGCCTGTGGTTAGCAGCATTAAAAGATTATGCACTCTTGACTTTACCAGCCGAATTTTCTAGTCAGCTT
CCTCCAGATGGTGGAGCATTTTATACCCCTGAAACTATTGATACAGCTAGACTTCACTATCGGAATTCCTGGGCCCCAATTCTCCATGCG
GTGGCACTTTGGTTAAATAGCACAGGATTTACGTGCTCAGAGTCTACAGAAGCAGCAGCAATATCTGGTTTACAAAAACGTTCTACATCT
GTCAATTTAAACCAGGCATCAGGAGCAGTGGGTAGTGCTAAATCTTTGCCAGAAATTAACAAAGACAGAATGCATCTGATTTTAGGTGTG
AGTATACAGTTTCTTTGTTCCCCTAGACCTGAGGAGCCCATTGAACATGTTACAGCATGCCTGCAGGCCTTACATACCTTGCTAGACTCC
CCTTATGCTCGAGTCCATATTGCAGAAGATCAGCTGATAGGTGTTGAGTTGCTGAGTGTTTTGCACCGCCTTCTATTGACCTGGAATCCA
TCATCTGTCCAGCTGTTGGTTACTGGAGTTGTACAACAGATAGTAAGAGCTGCTCAGGATTATTTGCAAGAGAAAAGAAACACTCTAAGA
TGTATGACAATCCTGCCCACAATTCTGTTCTTAATTGCAAGAATATTGAAAGACACAGCAATAAAGTCTGCAGATAATCAGGTTCCTCCA
CCAGTCAGTGCAGCTCTTCAAGGGATTAAAAGTATTGTGACACTTTCAATGGCCAAAACTGAGGCTGGCGTTCAAAAACAGTGGACAGCT
CTGATTCGTAGCACGCTTGCTTGCATCCTGGAATATTCTCAACCAGAAGACTCTGTACCTACACCTGATGAAGTAAGCATGCTAACAGCA
ATTGCACTCTTCCTGTGGTCTGCTAGTAATGAAATAATAGGAGTCCAGTCATTACAGAATGGCTGCATGAACAGATTTAAAAATGCATTA
AATTCATGCGACCCATGGGTTCAAGCCAAATGTTACCAGCTTCTCCTCTCAGTCTTCCAGCATTCCAATCGTGCCCTTTCAACTCCTTAT
ATTCATTCATTAGCTCCAATAGTGGTTGAAAAGCTAAAAGCTGTTGAAAGAAACAGACCAGCCAGTAACATAGAGCTTTTAGCGGTTCAA
GAAGGAATAAAAGTTCTTGAAACACTGGTTGCTCTTGGTGAAGAACAAAACAGAGTCCAGCTACTTGCTCTTTTAGTTCCCACTTTGATA
TCTTACCTGCTGGATGAAAATTCTTTTGCCTCAGCAAGTTCAGCTTCCAAAGATCTTCATGAGTTTGCACTCCAGAATTTAATGCATATT
GGACCTCTGTATCCACATGCTTTCAAGACAGTAATGGGGGCTGCTCCTGAGTTGAAAGTGCGTCTAGAAACTGCCGTTCGAGCAAGCCAA
GCGAGCAAAGCTAAAGCGGCTGCCAGACAACCAGCCCCCGCCATACATTCTGCACCAACAATTAAGCTAAAAACAAGTTTTTTTTAATTT
GTAATTTCATTTATTTGTATTTATGTTGTCAACTAGCCCCTAATTAGTGATGGCCACTGTATCATTCCAGGCTACCTATGGGTTCTGTTT
TATTTGTATATTGGTATTATAGTGCTTCCAAGTAGGTTAAGTGAAATAATGCTCACACCACTTATTGATTTTTAAGGAGTGATTTTTTTT
ATCATGTGGTGAATATGTTTTCATTTTCCTCCTAATAATGTTTCTCTTTTGTTAACTTATTTATTTTTCAAACACTGAGCCATAGTCTTA
AATTTAAATGCTAAAAACAATTGTATCATGTAGTCGGGCAGCCTATTGATACTGTCAGGGGAAAAAAATGGGTCAGAACTCAGCATCTGT
CATGAAAAAAATCAATTGAAAAACAAGCAGATTTTAAATTTTGAAGTAATCAAAATAATGGAAAGTGTCTGTTTTGTGGTGTATATACTA

>87738_87738_8_STRN-HEATR5B_STRN_chr2_37121041_ENST00000379213_HEATR5B_chr2_37293053_ENST00000354531_length(amino acids)=1888AA_BP=298
MDEQAGPGVFFSNNHPGAGGAKGLGPLAGAARAQYSLPGILHFLQHEWARFEVERAQWEVERAELQAQIAFLQGERKGQENLKKDLVRRI
KMLEYALKQERAKYHKLKYGTELNQGDMKPPSYDSDEGNETEVQPQQNSQLMWKQGRQLLRQYLQEVGYTDTILDVKSKRVRALLGFSSD
VTDREDDKNQDSVVNGTEAEVKETAMIAKSELTDSASVLDNFKFLESAAADFSDEDEDDDVDGREKSVIDTSTIVRKKALPDSGEDRDTK
EALKEFDFLVTSEEGDNESRSAGDGTDWEAVVNDTSGENKSGAADIAASQHVMVCALQELGSLVQSLNATASPLIQEASIGLLEIVTSVL
LHPSMAARLAAAWCLRCVAVALPFQLTPFLDRCAERLNNLKTSPEAVSGYSFAMAALLGGVHQCPLGIPHAKGKMVVSIAEDLLRTAAQN
SRLSLQRTQAGWLLLGALMTLGPSVVRYHLPKMLLLWRNVFPRSLKELEAEKARGDSFTWQVTLEGRAGALCAMRSFVAHCPELLTEDVI
RKLMTPIECAMTMMSHIPSVMKAHGAHLKASAAMVRLRLYDILALLPPKTYEGSFNALLRELVAEFTLTDNSANTTTSLLRSLCHYDDSV
LLGSWLQETDHKSIEDQLQPNSASGSGALEHDPSSIYLRIPAGEAVPGPLPLGVSVIDASVALFGVVFPHVSYKHRLQMLDHFAECVKQA
KGVRQQAVQLNIFTAVLSALKGLAENKSTLGPEEVRKSALTLVMGPLDNPNPILRCAAGEALGRMAQVVGEATFIARMAQYSFDKLKSAR
DVVSRTGHSLALGCLHRYVGGIGSGQHLKTSVSILLALAQDGTSPEVQTWSLHSLALIVDSSGPMYRGYVEPTLSLVLTLLLTVPPSHTE
VHQCLGRCLGAIITTVGPELQGNGATTSTIRSSCLVGCAITQDHSDSLVQAAAISCLQQLHMFAPRHVNLSSLVPSLCVHLCSSHLLLRR
AAVACLRQLAQREAAEVCEYAMSLAKNTGDKESSSANVSPFAPGVSSRTDIHCRHQGVNITETGLEGLLFGMLDRETDRKLCSDIHDTLG
HMLSSLAVEKLSHWLMLCKDVLAASSDMSTATLLSSGKDEEAEKKDEMDDDTMFTTLGEEDKSKPFVAPRWATRVFAADCLCRIINLCEN
ADQAHFDLALARSAKLRNPTNDLLVLHLSDLIRMAFMAATDHSNQLRMAGLQALEDIIKKFASVPEPEFPGHVILEQYQANVGAALRPAF
SQDTPSDIIAKACQVCSTWIGSGVVSDLNDLRRVHNLLVSSLDKVQAGKGSSSQLYRESATTMEKLAVLKAWAEVYVVAMNIKKEAESKP
KRAIKNTDDDDDDCGTIDELPPDSLITLVQPELPTLSRLWLAALKDYALLTLPAEFSSQLPPDGGAFYTPETIDTARLHYRNSWAPILHA
VALWLNSTGFTCSESTEAAAISGLQKRSTSVNLNQASGAVGSAKSLPEINKDRMHLILGVSIQFLCSPRPEEPIEHVTACLQALHTLLDS
PYARVHIAEDQLIGVELLSVLHRLLLTWNPSSVQLLVTGVVQQIVRAAQDYLQEKRNTLRCMTILPTILFLIARILKDTAIKSADNQVPP
PVSAALQGIKSIVTLSMAKTEAGVQKQWTALIRSTLACILEYSQPEDSVPTPDEVSMLTAIALFLWSASNEIIGVQSLQNGCMNRFKNAL
NSCDPWVQAKCYQLLLSVFQHSNRALSTPYIHSLAPIVVEKLKAVERNRPASNIELLAVQEGIKVLETLVALGEEQNRVQLLALLVPTLI

--------------------------------------------------------------

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Fusion Gene PPI Analysis for STRN-HEATR5B


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for STRN-HEATR5B


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for STRN-HEATR5B


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource