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	Fusion Gene Summary
	Fusion Gene ORF analysis
	Fusion Genomic Features
	Fusion Protein Features
	Fusion Gene Sequence
	Fusion Gene PPI analysis
	Related Drugs
	Related Diseases

Fusion gene:STX3-MS4A15 (FusionGDB2 ID:87814)

Fusion Gene Summary for STX3-MS4A15

Fusion gene summary

Fusion gene information	Fusion gene name: STX3-MS4A15
	Fusion gene ID: 87814
		Hgene	Tgene
	Gene symbol	STX3	MS4A15
	Gene ID	6809	219995
	Gene name	syntaxin 3	membrane spanning 4-domains A15
	Synonyms	STX3A	-
	Cytomap	11q12.1	11q12.2
	Type of gene	protein-coding	protein-coding
	Description	syntaxin-3syntaxin 3A	membrane-spanning 4-domains subfamily A member 15
	Modification date	20200327	20200313
	UniProtAcc	.	.
	Ensembl transtripts involved in fusion gene	ENST00000337979, ENST00000529177, ENST00000535361, ENST00000437946, ENST00000300150,	ENST00000337911, ENST00000405633, ENST00000528170,
Fusion gene scores	* DoF score	9 X 8 X 6=432	3 X 7 X 3=63
	# samples	10	5
	** MAII score	log2(10/432*10)=-2.11103131238874 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0	log2(5/63*10)=-0.333423733725192 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0
Context	PubMed: STX3 [Title/Abstract] AND MS4A15 [Title/Abstract] AND fusion [Title/Abstract]
Most frequent breakpoint	STX3(59523108)-MS4A15(60535040), # samples:3
Anticipated loss of major functional domain due to fusion event.

* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Partner

Gene

GO ID

GO term

PubMed ID

Fusion gene breakpoints across STX3 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion gene breakpoints across MS4A15 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

Source	Disease	Sample	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
ChimerDB4	PRAD	TCGA-HC-7209-01A	STX3	chr11	59523107	+	MS4A15	chr11	60535005	+
ChimerDB4	PRAD	TCGA-HC-7209-01A	STX3	chr11	59523107	+	MS4A15	chr11	60535039	+
ChimerDB4	PRAD	TCGA-HC-7209-01A	STX3	chr11	59523107	+	MS4A15	chr11	60538763	+
ChimerDB4	PRAD	TCGA-HC-7209-01A	STX3	chr11	59523108	-	MS4A15	chr11	60535040	+
ChimerDB4	PRAD	TCGA-HC-7209-01A	STX3	chr11	59523108	+	MS4A15	chr11	60535040	+
ChimerDB4	PRAD	TCGA-HC-7209	STX3	chr11	59523108	+	MS4A15	chr11	60535006	+
ChimerDB4	PRAD	TCGA-HC-7209	STX3	chr11	59523108	+	MS4A15	chr11	60535039	+
ChimerDB4	PRAD	TCGA-HC-7209	STX3	chr11	59523108	+	MS4A15	chr11	60535040	+
ChimerDB4	PRAD	TCGA-HC-7209	STX3	chr11	59523108	+	MS4A15	chr11	60538764	+

Top

Fusion Gene ORF analysis for STX3-MS4A15

Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

ORF	Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
5CDS-5UTR	ENST00000337979	ENST00000337911	STX3	chr11	59523107	+	MS4A15	chr11	60535039	+
5CDS-5UTR	ENST00000337979	ENST00000337911	STX3	chr11	59523108	+	MS4A15	chr11	60535040	+
5CDS-5UTR	ENST00000337979	ENST00000337911	STX3	chr11	59523108	+	MS4A15	chr11	60535039	+
5CDS-5UTR	ENST00000337979	ENST00000405633	STX3	chr11	59523107	+	MS4A15	chr11	60535039	+
5CDS-5UTR	ENST00000337979	ENST00000405633	STX3	chr11	59523108	+	MS4A15	chr11	60535040	+
5CDS-5UTR	ENST00000337979	ENST00000405633	STX3	chr11	59523108	+	MS4A15	chr11	60535039	+
5CDS-5UTR	ENST00000529177	ENST00000337911	STX3	chr11	59523107	+	MS4A15	chr11	60535039	+
5CDS-5UTR	ENST00000529177	ENST00000337911	STX3	chr11	59523108	+	MS4A15	chr11	60535040	+
5CDS-5UTR	ENST00000529177	ENST00000337911	STX3	chr11	59523108	+	MS4A15	chr11	60535039	+
5CDS-5UTR	ENST00000529177	ENST00000405633	STX3	chr11	59523107	+	MS4A15	chr11	60535039	+
5CDS-5UTR	ENST00000529177	ENST00000405633	STX3	chr11	59523108	+	MS4A15	chr11	60535040	+
5CDS-5UTR	ENST00000529177	ENST00000405633	STX3	chr11	59523108	+	MS4A15	chr11	60535039	+
5CDS-5UTR	ENST00000535361	ENST00000337911	STX3	chr11	59523107	+	MS4A15	chr11	60535039	+
5CDS-5UTR	ENST00000535361	ENST00000337911	STX3	chr11	59523108	+	MS4A15	chr11	60535040	+
5CDS-5UTR	ENST00000535361	ENST00000337911	STX3	chr11	59523108	+	MS4A15	chr11	60535039	+
5CDS-5UTR	ENST00000535361	ENST00000405633	STX3	chr11	59523107	+	MS4A15	chr11	60535039	+
5CDS-5UTR	ENST00000535361	ENST00000405633	STX3	chr11	59523108	+	MS4A15	chr11	60535040	+
5CDS-5UTR	ENST00000535361	ENST00000405633	STX3	chr11	59523108	+	MS4A15	chr11	60535039	+
5CDS-intron	ENST00000337979	ENST00000337911	STX3	chr11	59523107	+	MS4A15	chr11	60535005	+
5CDS-intron	ENST00000337979	ENST00000337911	STX3	chr11	59523108	+	MS4A15	chr11	60535006	+
5CDS-intron	ENST00000337979	ENST00000405633	STX3	chr11	59523107	+	MS4A15	chr11	60535005	+
5CDS-intron	ENST00000337979	ENST00000405633	STX3	chr11	59523108	+	MS4A15	chr11	60535006	+
5CDS-intron	ENST00000337979	ENST00000528170	STX3	chr11	59523107	+	MS4A15	chr11	60535005	+
5CDS-intron	ENST00000337979	ENST00000528170	STX3	chr11	59523107	+	MS4A15	chr11	60535039	+
5CDS-intron	ENST00000337979	ENST00000528170	STX3	chr11	59523108	+	MS4A15	chr11	60535040	+
5CDS-intron	ENST00000337979	ENST00000528170	STX3	chr11	59523108	+	MS4A15	chr11	60535006	+
5CDS-intron	ENST00000337979	ENST00000528170	STX3	chr11	59523108	+	MS4A15	chr11	60535039	+
5CDS-intron	ENST00000529177	ENST00000337911	STX3	chr11	59523107	+	MS4A15	chr11	60535005	+
5CDS-intron	ENST00000529177	ENST00000337911	STX3	chr11	59523108	+	MS4A15	chr11	60535006	+
5CDS-intron	ENST00000529177	ENST00000405633	STX3	chr11	59523107	+	MS4A15	chr11	60535005	+
5CDS-intron	ENST00000529177	ENST00000405633	STX3	chr11	59523108	+	MS4A15	chr11	60535006	+
5CDS-intron	ENST00000529177	ENST00000528170	STX3	chr11	59523107	+	MS4A15	chr11	60535005	+
5CDS-intron	ENST00000529177	ENST00000528170	STX3	chr11	59523107	+	MS4A15	chr11	60535039	+
5CDS-intron	ENST00000529177	ENST00000528170	STX3	chr11	59523108	+	MS4A15	chr11	60535040	+
5CDS-intron	ENST00000529177	ENST00000528170	STX3	chr11	59523108	+	MS4A15	chr11	60535006	+
5CDS-intron	ENST00000529177	ENST00000528170	STX3	chr11	59523108	+	MS4A15	chr11	60535039	+
5CDS-intron	ENST00000535361	ENST00000337911	STX3	chr11	59523107	+	MS4A15	chr11	60535005	+
5CDS-intron	ENST00000535361	ENST00000337911	STX3	chr11	59523108	+	MS4A15	chr11	60535006	+
5CDS-intron	ENST00000535361	ENST00000405633	STX3	chr11	59523107	+	MS4A15	chr11	60535005	+
5CDS-intron	ENST00000535361	ENST00000405633	STX3	chr11	59523108	+	MS4A15	chr11	60535006	+
5CDS-intron	ENST00000535361	ENST00000528170	STX3	chr11	59523107	+	MS4A15	chr11	60535005	+
5CDS-intron	ENST00000535361	ENST00000528170	STX3	chr11	59523107	+	MS4A15	chr11	60535039	+
5CDS-intron	ENST00000535361	ENST00000528170	STX3	chr11	59523108	+	MS4A15	chr11	60535040	+
5CDS-intron	ENST00000535361	ENST00000528170	STX3	chr11	59523108	+	MS4A15	chr11	60535006	+
5CDS-intron	ENST00000535361	ENST00000528170	STX3	chr11	59523108	+	MS4A15	chr11	60535039	+
5UTR-3CDS	ENST00000437946	ENST00000337911	STX3	chr11	59523107	+	MS4A15	chr11	60538763	+
5UTR-3CDS	ENST00000437946	ENST00000337911	STX3	chr11	59523108	+	MS4A15	chr11	60538764	+
5UTR-3CDS	ENST00000437946	ENST00000405633	STX3	chr11	59523107	+	MS4A15	chr11	60538763	+
5UTR-3CDS	ENST00000437946	ENST00000405633	STX3	chr11	59523108	+	MS4A15	chr11	60538764	+
5UTR-3CDS	ENST00000437946	ENST00000528170	STX3	chr11	59523107	+	MS4A15	chr11	60538763	+
5UTR-3CDS	ENST00000437946	ENST00000528170	STX3	chr11	59523108	+	MS4A15	chr11	60538764	+
5UTR-5UTR	ENST00000437946	ENST00000337911	STX3	chr11	59523107	+	MS4A15	chr11	60535039	+
5UTR-5UTR	ENST00000437946	ENST00000337911	STX3	chr11	59523108	+	MS4A15	chr11	60535040	+
5UTR-5UTR	ENST00000437946	ENST00000337911	STX3	chr11	59523108	+	MS4A15	chr11	60535039	+
5UTR-5UTR	ENST00000437946	ENST00000405633	STX3	chr11	59523107	+	MS4A15	chr11	60535039	+
5UTR-5UTR	ENST00000437946	ENST00000405633	STX3	chr11	59523108	+	MS4A15	chr11	60535040	+
5UTR-5UTR	ENST00000437946	ENST00000405633	STX3	chr11	59523108	+	MS4A15	chr11	60535039	+
5UTR-intron	ENST00000437946	ENST00000337911	STX3	chr11	59523107	+	MS4A15	chr11	60535005	+
5UTR-intron	ENST00000437946	ENST00000337911	STX3	chr11	59523108	+	MS4A15	chr11	60535006	+
5UTR-intron	ENST00000437946	ENST00000405633	STX3	chr11	59523107	+	MS4A15	chr11	60535005	+
5UTR-intron	ENST00000437946	ENST00000405633	STX3	chr11	59523108	+	MS4A15	chr11	60535006	+
5UTR-intron	ENST00000437946	ENST00000528170	STX3	chr11	59523107	+	MS4A15	chr11	60535005	+
5UTR-intron	ENST00000437946	ENST00000528170	STX3	chr11	59523107	+	MS4A15	chr11	60535039	+
5UTR-intron	ENST00000437946	ENST00000528170	STX3	chr11	59523108	+	MS4A15	chr11	60535040	+
5UTR-intron	ENST00000437946	ENST00000528170	STX3	chr11	59523108	+	MS4A15	chr11	60535006	+
5UTR-intron	ENST00000437946	ENST00000528170	STX3	chr11	59523108	+	MS4A15	chr11	60535039	+
In-frame	ENST00000337979	ENST00000337911	STX3	chr11	59523107	+	MS4A15	chr11	60538763	+
In-frame	ENST00000337979	ENST00000337911	STX3	chr11	59523108	+	MS4A15	chr11	60538764	+
In-frame	ENST00000337979	ENST00000405633	STX3	chr11	59523107	+	MS4A15	chr11	60538763	+
In-frame	ENST00000337979	ENST00000405633	STX3	chr11	59523108	+	MS4A15	chr11	60538764	+
In-frame	ENST00000337979	ENST00000528170	STX3	chr11	59523107	+	MS4A15	chr11	60538763	+
In-frame	ENST00000337979	ENST00000528170	STX3	chr11	59523108	+	MS4A15	chr11	60538764	+
In-frame	ENST00000529177	ENST00000337911	STX3	chr11	59523107	+	MS4A15	chr11	60538763	+
In-frame	ENST00000529177	ENST00000337911	STX3	chr11	59523108	+	MS4A15	chr11	60538764	+
In-frame	ENST00000529177	ENST00000405633	STX3	chr11	59523107	+	MS4A15	chr11	60538763	+
In-frame	ENST00000529177	ENST00000405633	STX3	chr11	59523108	+	MS4A15	chr11	60538764	+
In-frame	ENST00000529177	ENST00000528170	STX3	chr11	59523107	+	MS4A15	chr11	60538763	+
In-frame	ENST00000529177	ENST00000528170	STX3	chr11	59523108	+	MS4A15	chr11	60538764	+
In-frame	ENST00000535361	ENST00000337911	STX3	chr11	59523107	+	MS4A15	chr11	60538763	+
In-frame	ENST00000535361	ENST00000337911	STX3	chr11	59523108	+	MS4A15	chr11	60538764	+
In-frame	ENST00000535361	ENST00000405633	STX3	chr11	59523107	+	MS4A15	chr11	60538763	+
In-frame	ENST00000535361	ENST00000405633	STX3	chr11	59523108	+	MS4A15	chr11	60538764	+
In-frame	ENST00000535361	ENST00000528170	STX3	chr11	59523107	+	MS4A15	chr11	60538763	+
In-frame	ENST00000535361	ENST00000528170	STX3	chr11	59523108	+	MS4A15	chr11	60538764	+
intron-3CDS	ENST00000300150	ENST00000337911	STX3	chr11	59523107	+	MS4A15	chr11	60538763	+
intron-3CDS	ENST00000300150	ENST00000337911	STX3	chr11	59523108	+	MS4A15	chr11	60538764	+
intron-3CDS	ENST00000300150	ENST00000405633	STX3	chr11	59523107	+	MS4A15	chr11	60538763	+
intron-3CDS	ENST00000300150	ENST00000405633	STX3	chr11	59523108	+	MS4A15	chr11	60538764	+
intron-3CDS	ENST00000300150	ENST00000528170	STX3	chr11	59523107	+	MS4A15	chr11	60538763	+
intron-3CDS	ENST00000300150	ENST00000528170	STX3	chr11	59523108	+	MS4A15	chr11	60538764	+
intron-5UTR	ENST00000300150	ENST00000337911	STX3	chr11	59523107	+	MS4A15	chr11	60535039	+
intron-5UTR	ENST00000300150	ENST00000337911	STX3	chr11	59523108	+	MS4A15	chr11	60535040	+
intron-5UTR	ENST00000300150	ENST00000337911	STX3	chr11	59523108	+	MS4A15	chr11	60535039	+
intron-5UTR	ENST00000300150	ENST00000405633	STX3	chr11	59523107	+	MS4A15	chr11	60535039	+
intron-5UTR	ENST00000300150	ENST00000405633	STX3	chr11	59523108	+	MS4A15	chr11	60535040	+
intron-5UTR	ENST00000300150	ENST00000405633	STX3	chr11	59523108	+	MS4A15	chr11	60535039	+
intron-intron	ENST00000300150	ENST00000337911	STX3	chr11	59523107	+	MS4A15	chr11	60535005	+
intron-intron	ENST00000300150	ENST00000337911	STX3	chr11	59523108	+	MS4A15	chr11	60535006	+
intron-intron	ENST00000300150	ENST00000405633	STX3	chr11	59523107	+	MS4A15	chr11	60535005	+
intron-intron	ENST00000300150	ENST00000405633	STX3	chr11	59523108	+	MS4A15	chr11	60535006	+
intron-intron	ENST00000300150	ENST00000528170	STX3	chr11	59523107	+	MS4A15	chr11	60535005	+
intron-intron	ENST00000300150	ENST00000528170	STX3	chr11	59523107	+	MS4A15	chr11	60535039	+
intron-intron	ENST00000300150	ENST00000528170	STX3	chr11	59523108	+	MS4A15	chr11	60535040	+
intron-intron	ENST00000300150	ENST00000528170	STX3	chr11	59523108	+	MS4A15	chr11	60535006	+
intron-intron	ENST00000300150	ENST00000528170	STX3	chr11	59523108	+	MS4A15	chr11	60535039	+

ORFfinder result based on the fusion transcript sequence of in-frame fusion genes.

Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	Seq length (transcript)	BP loci (transcript)	Predicted start (transcript)	Predicted stop (transcript)	Seq length (amino acids)
ENST00000337979	STX3	chr11	59523108	+	ENST00000528170	MS4A15	chr11	60538764	+	1036	577	3	920	305
ENST00000337979	STX3	chr11	59523108	+	ENST00000337911	MS4A15	chr11	60538764	+	1968	577	3	920	305
ENST00000337979	STX3	chr11	59523108	+	ENST00000405633	MS4A15	chr11	60538764	+	1968	577	3	920	305
ENST00000535361	STX3	chr11	59523108	+	ENST00000528170	MS4A15	chr11	60538764	+	1036	577	3	920	305
ENST00000535361	STX3	chr11	59523108	+	ENST00000337911	MS4A15	chr11	60538764	+	1968	577	3	920	305
ENST00000535361	STX3	chr11	59523108	+	ENST00000405633	MS4A15	chr11	60538764	+	1968	577	3	920	305
ENST00000529177	STX3	chr11	59523108	+	ENST00000528170	MS4A15	chr11	60538764	+	643	184	28	558	176
ENST00000529177	STX3	chr11	59523108	+	ENST00000337911	MS4A15	chr11	60538764	+	1575	184	856	1515	219
ENST00000529177	STX3	chr11	59523108	+	ENST00000405633	MS4A15	chr11	60538764	+	1575	184	856	1515	219
ENST00000337979	STX3	chr11	59523107	+	ENST00000528170	MS4A15	chr11	60538763	+	1036	577	3	920	305
ENST00000337979	STX3	chr11	59523107	+	ENST00000337911	MS4A15	chr11	60538763	+	1968	577	3	920	305
ENST00000337979	STX3	chr11	59523107	+	ENST00000405633	MS4A15	chr11	60538763	+	1968	577	3	920	305
ENST00000535361	STX3	chr11	59523107	+	ENST00000528170	MS4A15	chr11	60538763	+	1036	577	3	920	305
ENST00000535361	STX3	chr11	59523107	+	ENST00000337911	MS4A15	chr11	60538763	+	1968	577	3	920	305
ENST00000535361	STX3	chr11	59523107	+	ENST00000405633	MS4A15	chr11	60538763	+	1968	577	3	920	305
ENST00000529177	STX3	chr11	59523107	+	ENST00000528170	MS4A15	chr11	60538763	+	643	184	28	558	176
ENST00000529177	STX3	chr11	59523107	+	ENST00000337911	MS4A15	chr11	60538763	+	1575	184	856	1515	219
ENST00000529177	STX3	chr11	59523107	+	ENST00000405633	MS4A15	chr11	60538763	+	1575	184	856	1515	219

DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.

Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	No-coding score	Coding score
ENST00000337979	ENST00000528170	STX3	chr11	59523108	+	MS4A15	chr11	60538764	+	0.007286352	0.99271363
ENST00000337979	ENST00000337911	STX3	chr11	59523108	+	MS4A15	chr11	60538764	+	0.40480843	0.5951916
ENST00000337979	ENST00000405633	STX3	chr11	59523108	+	MS4A15	chr11	60538764	+	0.40480843	0.5951916
ENST00000535361	ENST00000528170	STX3	chr11	59523108	+	MS4A15	chr11	60538764	+	0.007286352	0.99271363
ENST00000535361	ENST00000337911	STX3	chr11	59523108	+	MS4A15	chr11	60538764	+	0.40480843	0.5951916
ENST00000535361	ENST00000405633	STX3	chr11	59523108	+	MS4A15	chr11	60538764	+	0.40480843	0.5951916
ENST00000529177	ENST00000528170	STX3	chr11	59523108	+	MS4A15	chr11	60538764	+	0.004502405	0.9954976
ENST00000529177	ENST00000337911	STX3	chr11	59523108	+	MS4A15	chr11	60538764	+	0.30615252	0.6938475
ENST00000529177	ENST00000405633	STX3	chr11	59523108	+	MS4A15	chr11	60538764	+	0.30615252	0.6938475
ENST00000337979	ENST00000528170	STX3	chr11	59523107	+	MS4A15	chr11	60538763	+	0.007286352	0.99271363
ENST00000337979	ENST00000337911	STX3	chr11	59523107	+	MS4A15	chr11	60538763	+	0.40480843	0.5951916
ENST00000337979	ENST00000405633	STX3	chr11	59523107	+	MS4A15	chr11	60538763	+	0.40480843	0.5951916
ENST00000535361	ENST00000528170	STX3	chr11	59523107	+	MS4A15	chr11	60538763	+	0.007286352	0.99271363
ENST00000535361	ENST00000337911	STX3	chr11	59523107	+	MS4A15	chr11	60538763	+	0.40480843	0.5951916
ENST00000535361	ENST00000405633	STX3	chr11	59523107	+	MS4A15	chr11	60538763	+	0.40480843	0.5951916
ENST00000529177	ENST00000528170	STX3	chr11	59523107	+	MS4A15	chr11	60538763	+	0.004502405	0.9954976
ENST00000529177	ENST00000337911	STX3	chr11	59523107	+	MS4A15	chr11	60538763	+	0.30615252	0.6938475
ENST00000529177	ENST00000405633	STX3	chr11	59523107	+	MS4A15	chr11	60538763	+	0.30615252	0.6938475

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Fusion Genomic Features for STX3-MS4A15

FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.

Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	1-p	p (fusion gene breakpoint)
STX3	chr11	59523108	+	MS4A15	chr11	60535039	+	5.09E-05	0.9999491
STX3	chr11	59523108	+	MS4A15	chr11	60535039	+	5.09E-05	0.9999491
STX3	chr11	59523108	+	MS4A15	chr11	60538763	+	1.63E-07	0.9999999
STX3	chr11	59523108	+	MS4A15	chr11	60538763	+	1.63E-07	0.9999999
STX3	chr11	59523108	+	MS4A15	chr11	60535005	+	1.29E-08	1
STX3	chr11	59523108	+	MS4A15	chr11	60535005	+	1.29E-08	1
STX3	chr11	59523108	+	MS4A15	chr11	60535039	+	5.09E-05	0.9999491
STX3	chr11	59523108	+	MS4A15	chr11	60535039	+	5.09E-05	0.9999491
STX3	chr11	59523108	+	MS4A15	chr11	60538763	+	1.63E-07	0.9999999
STX3	chr11	59523108	+	MS4A15	chr11	60538763	+	1.63E-07	0.9999999
STX3	chr11	59523108	+	MS4A15	chr11	60535005	+	1.29E-08	1
STX3	chr11	59523108	+	MS4A15	chr11	60535005	+	1.29E-08	1

Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.

Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for STX3-MS4A15

Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr11:59523108/chr11:60535040)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.

Main function of each fusion partner protein. (from UniProt)

Hgene	Tgene
.	.
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.	FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at
download page

* Minus value of BPloci means that the break pointn is located before the CDS.

- In-frame and retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

Tgene

MS4A15

chr11:59523107

chr11:60538763

ENST00000337911

100_120

148.0

Transmembrane

Helical

Tgene

MS4A15

chr11:59523107

chr11:60538763

ENST00000337911

144_164

148.0

Transmembrane

Helical

Tgene

MS4A15

chr11:59523107

chr11:60538763

ENST00000337911

173_193

148.0

Transmembrane

Helical

Tgene

MS4A15

chr11:59523107

chr11:60538763

ENST00000337911

73_93

148.0

Transmembrane

Helical

Tgene

MS4A15

chr11:59523107

chr11:60538763

ENST00000405633

144_164

116

241.0

Transmembrane

Helical

Tgene

MS4A15

chr11:59523107

chr11:60538763

ENST00000405633

173_193

116

241.0

Transmembrane

Helical

Tgene

MS4A15

chr11:59523108

chr11:60538764

ENST00000337911

100_120

148.0

Transmembrane

Helical

Tgene

MS4A15

chr11:59523108

chr11:60538764

ENST00000337911

144_164

148.0

Transmembrane

Helical

Tgene

MS4A15

chr11:59523108

chr11:60538764

ENST00000337911

173_193

148.0

Transmembrane

Helical

Tgene

MS4A15

chr11:59523108

chr11:60538764

ENST00000337911

73_93

148.0

Transmembrane

Helical

Tgene

MS4A15

chr11:59523108

chr11:60538764

ENST00000405633

144_164

116

241.0

Transmembrane

Helical

Tgene

MS4A15

chr11:59523108

chr11:60538764

ENST00000405633

173_193

116

241.0

Transmembrane

Helical

- In-frame and not-retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

Hgene

STX3

chr11:59523107

chr11:60538763

ENST00000337979

32_111

715.0

Coiled coil

Ontology_term=ECO:0000255

Hgene

STX3

chr11:59523107

chr11:60538763

ENST00000529177

32_111

278.0

Coiled coil

Ontology_term=ECO:0000255

Hgene

STX3

chr11:59523107

chr11:60538763

ENST00000535361

32_111

1736.3333333333333

Coiled coil

Ontology_term=ECO:0000255

Hgene

STX3

chr11:59523108

chr11:60538764

ENST00000337979

32_111

715.0

Coiled coil

Ontology_term=ECO:0000255

Hgene

STX3

chr11:59523108

chr11:60538764

ENST00000529177

32_111

278.0

Coiled coil

Ontology_term=ECO:0000255

Hgene

STX3

chr11:59523108

chr11:60538764

ENST00000535361

32_111

1736.3333333333333

Coiled coil

Ontology_term=ECO:0000255

Hgene

STX3

chr11:59523107

chr11:60538763

ENST00000337979

191_253

715.0

Domain

t-SNARE coiled-coil homology

Hgene

STX3

chr11:59523107

chr11:60538763

ENST00000529177

191_253

278.0

Domain

t-SNARE coiled-coil homology

Hgene

STX3

chr11:59523107

chr11:60538763

ENST00000535361

191_253

1736.3333333333333

Domain

t-SNARE coiled-coil homology

Hgene

STX3

chr11:59523108

chr11:60538764

ENST00000337979

191_253

715.0

Domain

t-SNARE coiled-coil homology

Hgene

STX3

chr11:59523108

chr11:60538764

ENST00000529177

191_253

278.0

Domain

t-SNARE coiled-coil homology

Hgene

STX3

chr11:59523108

chr11:60538764

ENST00000535361

191_253

1736.3333333333333

Domain

t-SNARE coiled-coil homology

Hgene

STX3

chr11:59523107

chr11:60538763

ENST00000337979

1_263

715.0

Topological domain

Cytoplasmic

Hgene

STX3

chr11:59523107

chr11:60538763

ENST00000337979

285_289

715.0

Topological domain

Extracellular

Hgene

STX3

chr11:59523107

chr11:60538763

ENST00000529177

1_263

278.0

Topological domain

Cytoplasmic

Hgene

STX3

chr11:59523107

chr11:60538763

ENST00000529177

285_289

278.0

Topological domain

Extracellular

Hgene

STX3

chr11:59523107

chr11:60538763

ENST00000535361

1_263

1736.3333333333333

Topological domain

Cytoplasmic

Hgene

STX3

chr11:59523107

chr11:60538763

ENST00000535361

285_289

1736.3333333333333

Topological domain

Extracellular

Hgene

STX3

chr11:59523108

chr11:60538764

ENST00000337979

1_263

715.0

Topological domain

Cytoplasmic

Hgene

STX3

chr11:59523108

chr11:60538764

ENST00000337979

285_289

715.0

Topological domain

Extracellular

Hgene

STX3

chr11:59523108

chr11:60538764

ENST00000529177

1_263

278.0

Topological domain

Cytoplasmic

Hgene

STX3

chr11:59523108

chr11:60538764

ENST00000529177

285_289

278.0

Topological domain

Extracellular

Hgene

STX3

chr11:59523108

chr11:60538764

ENST00000535361

1_263

1736.3333333333333

Topological domain

Cytoplasmic

Hgene

STX3

chr11:59523108

chr11:60538764

ENST00000535361

285_289

1736.3333333333333

Topological domain

Extracellular

Hgene

STX3

chr11:59523107

chr11:60538763

ENST00000337979

264_284

715.0

Transmembrane

Helical%3B Anchor for type IV membrane protein

Hgene

STX3

chr11:59523107

chr11:60538763

ENST00000529177

264_284

278.0

Transmembrane

Helical%3B Anchor for type IV membrane protein

Hgene

STX3

chr11:59523107

chr11:60538763

ENST00000535361

264_284

1736.3333333333333

Transmembrane

Helical%3B Anchor for type IV membrane protein

Hgene

STX3

chr11:59523108

chr11:60538764

ENST00000337979

264_284

715.0

Transmembrane

Helical%3B Anchor for type IV membrane protein

Hgene

STX3

chr11:59523108

chr11:60538764

ENST00000529177

264_284

278.0

Transmembrane

Helical%3B Anchor for type IV membrane protein

Hgene

STX3

chr11:59523108

chr11:60538764

ENST00000535361

264_284

1736.3333333333333

Transmembrane

Helical%3B Anchor for type IV membrane protein

Tgene

MS4A15

chr11:59523107

chr11:60538763

ENST00000405633

100_120

116

241.0

Transmembrane

Helical

Tgene

MS4A15

chr11:59523107

chr11:60538763

ENST00000405633

73_93

116

241.0

Transmembrane

Helical

Tgene

MS4A15

chr11:59523108

chr11:60538764

ENST00000405633

100_120

116

241.0

Transmembrane

Helical

Tgene

MS4A15

chr11:59523108

chr11:60538764

ENST00000405633

73_93

116

241.0

Transmembrane

Helical

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Fusion Gene Sequence for STX3-MS4A15

For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.

>87814_87814_1_STX3-MS4A15_STX3_chr11_59523107_ENST00000337979_MS4A15_chr11_60538763_ENST00000337911_length(transcript)=1968nt_BP=577nt
AGCTTGTCCCCGCCTAGCAAGGAGTCGGCTAAGAACTGGATCCTAGCGAGGAGCCCGGCACAGACAGCGAATGACCGCAGCCAGACAGTC
GCTCTTGCTCTTCCTCGGCCCTGCGGCAGGATCCGCCGGTGCAGGGGCCTCTCCCCGGACTCCACGCGTGTCTGGAGGGCTCTCGGGTTA
GGGAAGGGGGCTTTGGAGACGCCCCGGGCGGCCGGGCGGTGGCGGGACGCGGGCCCTTTAAGAAGGAGCGAGGGGCGCGGCCAGGTAGGG
GCGGGTCCAGGGCGGATCAGCGCTGCGCCGGCGCCGGCCCGGGAGCCGGATTTGGAGCGCGAGGCGCCGGTGGGGGCGGAGGGGGCTGCG
CGGCGGAGGCTCCCGTGGCCTCGGACGCTCCTCCTAGCTAGCGGCCGCCGCCCGCCGCCGCCTGCGCCTCCAGCTCCTTCGCCCCGGCGG
GCCCGGCCGCCGCTTCCGGCAGCTCACCTGGGAAGCGCTCACCTGGGACGCGCTCACCTGGGACGCGCTACCTGCCTCCGGGCGCCTGGG
CTTCAGGATGAAGGACCGTCTGGAGCAGCTGAAGGCCTTCATCATCTCCGGATCCCTCTCAGTGGCAGCCGAGAAGAACCACACCAGTTG
CCTGGTGAGGAGCAGCCTGGGCACCAACATCCTCAGCGTCATGGCGGCCTTTGCTGGGACAGCCATTCTGCTCATGGATTTTGGTGTTAC
CAACCGGGATGTGGACAGGGGCTATCTGGCCGTGCTTACTATCTTCACTGTCCTGGAGTTCTTCACAGCGGTCATTGCCATGCACTTCGG
GTGCCAAGCCATCCATGCCCAGGCCAGTGCACCTGTGATCTTCCTGCCAAACGCCTTCAGCGCAGACTTCAACATCCCCAGCCCGGCAGC
CTCTGCGCCCCCTGCCTATGACAATGTGGCATATGCCCAAGGAGTCGTCTGAGTAGCAGATGTGGCACCTGCGGGTGGAGTCCAGCCTTT
TCCCTCTGGGCCCAGCCTCTCCCCACCCCCACCTTGTTCATCAGGGGCCAGCCCCATCCCAGCTGCCCTCCCTCACCACATCTACACATA
CTCCGGCATCTGAGTGAAGTGTCCCCAGGGACATCTCTCCCACACTTTCCCCAGTGCTTTCTTTCTAAAAGACACCGGGCTGACGTCAGG
GGTGTGTGTCCTTCAGCTCCCTGAGCCCTGTCACCCTTCCAGGACACCCACCTTGTGCATCTAAGCATTTCTCTGCTCATTGGGGAAATC
CTGGCCTCATTGGAGACTCAGGTTCGAGGCCTGCCCTGACCCTCGGGCCTCGGGAAGGTCAGAGAGCCCGGAATCCTCCAGAATGGAAGA
GTCTGACTCTGGCATTCCACAGAGGTGCCGATACCAGGCCAAGGCCTCACAGCAGGGTAGTGGCCTGGCCGCAGGTCTCCTGGCCCCAAG
ATCAGCTCTGTCCTTTGTCATCTGTTGCCACATCCATGGAACTCAGGTTTCCTATTTGGAAACTAGAGTGTTGAACCAGATAAGGTTCAT
CAGGCCCTTCCAGCTCCCCAGGCTCCCTGAAGTCCTGGGTCTAGGCCAGGCATTGTCCCCCTGCTTCCTGGAAACCCTCATTTTCCTTGT
CTGTAATATGAAGTCAGCATTGGCCCCGCCCCCCACCCCCTACCATCTCCCAATGGAGGGGAGGTTGCAGGGGAGAGCTGCCGCCAGCCC
ACTCCTGAGGCACCACCACAGTCAGCATCGACAGGGGCACAGCAGTGGCAGTTTGGGACCTCCCTGTGCCTCTCAGCACTCCCTTCCCCA
CCCCCATAGCCCAAGGACAAGGCTACCACAGAAGGTTACCACAGGACCTGGGCTTCGTCTCCAGGGGACAAGGAGACACTGTCAGCCTGG

>87814_87814_1_STX3-MS4A15_STX3_chr11_59523107_ENST00000337979_MS4A15_chr11_60538763_ENST00000337911_length(amino acids)=305AA_BP=192
MSPPSKESAKNWILARSPAQTANDRSQTVALALPRPCGRIRRCRGLSPDSTRVWRALGLGKGALETPRAAGRWRDAGPLRRSEGRGQVGA
GPGRISAAPAPAREPDLEREAPVGAEGAARRRLPWPRTLLLASGRRPPPPAPPAPSPRRARPPLPAAHLGSAHLGRAHLGRATCLRAPGL
QDEGPSGAAEGLHHLRIPLSGSREEPHQLPGEEQPGHQHPQRHGGLCWDSHSAHGFWCYQPGCGQGLSGRAYYLHCPGVLHSGHCHALRV

--------------------------------------------------------------
>87814_87814_2_STX3-MS4A15_STX3_chr11_59523107_ENST00000337979_MS4A15_chr11_60538763_ENST00000405633_length(transcript)=1968nt_BP=577nt
AGCTTGTCCCCGCCTAGCAAGGAGTCGGCTAAGAACTGGATCCTAGCGAGGAGCCCGGCACAGACAGCGAATGACCGCAGCCAGACAGTC
GCTCTTGCTCTTCCTCGGCCCTGCGGCAGGATCCGCCGGTGCAGGGGCCTCTCCCCGGACTCCACGCGTGTCTGGAGGGCTCTCGGGTTA
GGGAAGGGGGCTTTGGAGACGCCCCGGGCGGCCGGGCGGTGGCGGGACGCGGGCCCTTTAAGAAGGAGCGAGGGGCGCGGCCAGGTAGGG
GCGGGTCCAGGGCGGATCAGCGCTGCGCCGGCGCCGGCCCGGGAGCCGGATTTGGAGCGCGAGGCGCCGGTGGGGGCGGAGGGGGCTGCG
CGGCGGAGGCTCCCGTGGCCTCGGACGCTCCTCCTAGCTAGCGGCCGCCGCCCGCCGCCGCCTGCGCCTCCAGCTCCTTCGCCCCGGCGG
GCCCGGCCGCCGCTTCCGGCAGCTCACCTGGGAAGCGCTCACCTGGGACGCGCTCACCTGGGACGCGCTACCTGCCTCCGGGCGCCTGGG
CTTCAGGATGAAGGACCGTCTGGAGCAGCTGAAGGCCTTCATCATCTCCGGATCCCTCTCAGTGGCAGCCGAGAAGAACCACACCAGTTG
CCTGGTGAGGAGCAGCCTGGGCACCAACATCCTCAGCGTCATGGCGGCCTTTGCTGGGACAGCCATTCTGCTCATGGATTTTGGTGTTAC
CAACCGGGATGTGGACAGGGGCTATCTGGCCGTGCTTACTATCTTCACTGTCCTGGAGTTCTTCACAGCGGTCATTGCCATGCACTTCGG
GTGCCAAGCCATCCATGCCCAGGCCAGTGCACCTGTGATCTTCCTGCCAAACGCCTTCAGCGCAGACTTCAACATCCCCAGCCCGGCAGC
CTCTGCGCCCCCTGCCTATGACAATGTGGCATATGCCCAAGGAGTCGTCTGAGTAGCAGATGTGGCACCTGCGGGTGGAGTCCAGCCTTT
TCCCTCTGGGCCCAGCCTCTCCCCACCCCCACCTTGTTCATCAGGGGCCAGCCCCATCCCAGCTGCCCTCCCTCACCACATCTACACATA
CTCCGGCATCTGAGTGAAGTGTCCCCAGGGACATCTCTCCCACACTTTCCCCAGTGCTTTCTTTCTAAAAGACACCGGGCTGACGTCAGG
GGTGTGTGTCCTTCAGCTCCCTGAGCCCTGTCACCCTTCCAGGACACCCACCTTGTGCATCTAAGCATTTCTCTGCTCATTGGGGAAATC
CTGGCCTCATTGGAGACTCAGGTTCGAGGCCTGCCCTGACCCTCGGGCCTCGGGAAGGTCAGAGAGCCCGGAATCCTCCAGAATGGAAGA
GTCTGACTCTGGCATTCCACAGAGGTGCCGATACCAGGCCAAGGCCTCACAGCAGGGTAGTGGCCTGGCCGCAGGTCTCCTGGCCCCAAG
ATCAGCTCTGTCCTTTGTCATCTGTTGCCACATCCATGGAACTCAGGTTTCCTATTTGGAAACTAGAGTGTTGAACCAGATAAGGTTCAT
CAGGCCCTTCCAGCTCCCCAGGCTCCCTGAAGTCCTGGGTCTAGGCCAGGCATTGTCCCCCTGCTTCCTGGAAACCCTCATTTTCCTTGT
CTGTAATATGAAGTCAGCATTGGCCCCGCCCCCCACCCCCTACCATCTCCCAATGGAGGGGAGGTTGCAGGGGAGAGCTGCCGCCAGCCC
ACTCCTGAGGCACCACCACAGTCAGCATCGACAGGGGCACAGCAGTGGCAGTTTGGGACCTCCCTGTGCCTCTCAGCACTCCCTTCCCCA
CCCCCATAGCCCAAGGACAAGGCTACCACAGAAGGTTACCACAGGACCTGGGCTTCGTCTCCAGGGGACAAGGAGACACTGTCAGCCTGG

>87814_87814_2_STX3-MS4A15_STX3_chr11_59523107_ENST00000337979_MS4A15_chr11_60538763_ENST00000405633_length(amino acids)=305AA_BP=192
MSPPSKESAKNWILARSPAQTANDRSQTVALALPRPCGRIRRCRGLSPDSTRVWRALGLGKGALETPRAAGRWRDAGPLRRSEGRGQVGA
GPGRISAAPAPAREPDLEREAPVGAEGAARRRLPWPRTLLLASGRRPPPPAPPAPSPRRARPPLPAAHLGSAHLGRAHLGRATCLRAPGL
QDEGPSGAAEGLHHLRIPLSGSREEPHQLPGEEQPGHQHPQRHGGLCWDSHSAHGFWCYQPGCGQGLSGRAYYLHCPGVLHSGHCHALRV

--------------------------------------------------------------
>87814_87814_3_STX3-MS4A15_STX3_chr11_59523107_ENST00000337979_MS4A15_chr11_60538763_ENST00000528170_length(transcript)=1036nt_BP=577nt
AGCTTGTCCCCGCCTAGCAAGGAGTCGGCTAAGAACTGGATCCTAGCGAGGAGCCCGGCACAGACAGCGAATGACCGCAGCCAGACAGTC
GCTCTTGCTCTTCCTCGGCCCTGCGGCAGGATCCGCCGGTGCAGGGGCCTCTCCCCGGACTCCACGCGTGTCTGGAGGGCTCTCGGGTTA
GGGAAGGGGGCTTTGGAGACGCCCCGGGCGGCCGGGCGGTGGCGGGACGCGGGCCCTTTAAGAAGGAGCGAGGGGCGCGGCCAGGTAGGG
GCGGGTCCAGGGCGGATCAGCGCTGCGCCGGCGCCGGCCCGGGAGCCGGATTTGGAGCGCGAGGCGCCGGTGGGGGCGGAGGGGGCTGCG
CGGCGGAGGCTCCCGTGGCCTCGGACGCTCCTCCTAGCTAGCGGCCGCCGCCCGCCGCCGCCTGCGCCTCCAGCTCCTTCGCCCCGGCGG
GCCCGGCCGCCGCTTCCGGCAGCTCACCTGGGAAGCGCTCACCTGGGACGCGCTCACCTGGGACGCGCTACCTGCCTCCGGGCGCCTGGG
CTTCAGGATGAAGGACCGTCTGGAGCAGCTGAAGGCCTTCATCATCTCCGGATCCCTCTCAGTGGCAGCCGAGAAGAACCACACCAGTTG
CCTGGTGAGGAGCAGCCTGGGCACCAACATCCTCAGCGTCATGGCGGCCTTTGCTGGGACAGCCATTCTGCTCATGGATTTTGGTGTTAC
CAACCGGGATGTGGACAGGGGCTATCTGGCCGTGCTTACTATCTTCACTGTCCTGGAGTTCTTCACAGCGGTCATTGCCATGCACTTCGG
GTGCCAAGCCATCCATGCCCAGGCCAGTGCACCTGTGATCTTCCTGCCAAACGCCTTCAGCGCAGACTTCAACATCCCCAGCCCGGCAGC
CTCTGCGCCCCCTGCCTATGACAATGTGGCATATGCCCAAGGAGTCGTCTGAGTAGCAGATGTGGCACCTGCGGGTGGAGTCCAGCCTTT

>87814_87814_3_STX3-MS4A15_STX3_chr11_59523107_ENST00000337979_MS4A15_chr11_60538763_ENST00000528170_length(amino acids)=305AA_BP=192
MSPPSKESAKNWILARSPAQTANDRSQTVALALPRPCGRIRRCRGLSPDSTRVWRALGLGKGALETPRAAGRWRDAGPLRRSEGRGQVGA
GPGRISAAPAPAREPDLEREAPVGAEGAARRRLPWPRTLLLASGRRPPPPAPPAPSPRRARPPLPAAHLGSAHLGRAHLGRATCLRAPGL
QDEGPSGAAEGLHHLRIPLSGSREEPHQLPGEEQPGHQHPQRHGGLCWDSHSAHGFWCYQPGCGQGLSGRAYYLHCPGVLHSGHCHALRV

--------------------------------------------------------------
>87814_87814_4_STX3-MS4A15_STX3_chr11_59523107_ENST00000529177_MS4A15_chr11_60538763_ENST00000337911_length(transcript)=1575nt_BP=184nt
CTAGCTAGCGGCCGCCGCCCGCCGCCGCCTGCGCCTCCAGCTCCTTCGCCCCGGCGGGCCCGGCCGCCGCTTCCGGCAGCTCACCTGGGA
AGCGCTCACCTGGGACGCGCTCACCTGGGACGCGCTACCTGCCTCCGGGCGCCTGGGCTTCAGGATGAAGGACCGTCTGGAGCAGCTGAA
GGCCTTCATCATCTCCGGATCCCTCTCAGTGGCAGCCGAGAAGAACCACACCAGTTGCCTGGTGAGGAGCAGCCTGGGCACCAACATCCT
CAGCGTCATGGCGGCCTTTGCTGGGACAGCCATTCTGCTCATGGATTTTGGTGTTACCAACCGGGATGTGGACAGGGGCTATCTGGCCGT
GCTTACTATCTTCACTGTCCTGGAGTTCTTCACAGCGGTCATTGCCATGCACTTCGGGTGCCAAGCCATCCATGCCCAGGCCAGTGCACC
TGTGATCTTCCTGCCAAACGCCTTCAGCGCAGACTTCAACATCCCCAGCCCGGCAGCCTCTGCGCCCCCTGCCTATGACAATGTGGCATA
TGCCCAAGGAGTCGTCTGAGTAGCAGATGTGGCACCTGCGGGTGGAGTCCAGCCTTTTCCCTCTGGGCCCAGCCTCTCCCCACCCCCACC
TTGTTCATCAGGGGCCAGCCCCATCCCAGCTGCCCTCCCTCACCACATCTACACATACTCCGGCATCTGAGTGAAGTGTCCCCAGGGACA
TCTCTCCCACACTTTCCCCAGTGCTTTCTTTCTAAAAGACACCGGGCTGACGTCAGGGGTGTGTGTCCTTCAGCTCCCTGAGCCCTGTCA
CCCTTCCAGGACACCCACCTTGTGCATCTAAGCATTTCTCTGCTCATTGGGGAAATCCTGGCCTCATTGGAGACTCAGGTTCGAGGCCTG
CCCTGACCCTCGGGCCTCGGGAAGGTCAGAGAGCCCGGAATCCTCCAGAATGGAAGAGTCTGACTCTGGCATTCCACAGAGGTGCCGATA
CCAGGCCAAGGCCTCACAGCAGGGTAGTGGCCTGGCCGCAGGTCTCCTGGCCCCAAGATCAGCTCTGTCCTTTGTCATCTGTTGCCACAT
CCATGGAACTCAGGTTTCCTATTTGGAAACTAGAGTGTTGAACCAGATAAGGTTCATCAGGCCCTTCCAGCTCCCCAGGCTCCCTGAAGT
CCTGGGTCTAGGCCAGGCATTGTCCCCCTGCTTCCTGGAAACCCTCATTTTCCTTGTCTGTAATATGAAGTCAGCATTGGCCCCGCCCCC
CACCCCCTACCATCTCCCAATGGAGGGGAGGTTGCAGGGGAGAGCTGCCGCCAGCCCACTCCTGAGGCACCACCACAGTCAGCATCGACA
GGGGCACAGCAGTGGCAGTTTGGGACCTCCCTGTGCCTCTCAGCACTCCCTTCCCCACCCCCATAGCCCAAGGACAAGGCTACCACAGAA
GGTTACCACAGGACCTGGGCTTCGTCTCCAGGGGACAAGGAGACACTGTCAGCCTGGTGTTCACCAGGCCTGGTAGATGAGATGGCTTGT

>87814_87814_4_STX3-MS4A15_STX3_chr11_59523107_ENST00000529177_MS4A15_chr11_60538763_ENST00000337911_length(amino acids)=219AA_BP=
MGKSWPHWRLRFEACPDPRASGRSESPESSRMEESDSGIPQRCRYQAKASQQGSGLAAGLLAPRSALSFVICCHIHGTQVSYLETRVLNQ
IRFIRPFQLPRLPEVLGLGQALSPCFLETLIFLVCNMKSALAPPPTPYHLPMEGRLQGRAAASPLLRHHHSQHRQGHSSGSLGPPCASQH

--------------------------------------------------------------
>87814_87814_5_STX3-MS4A15_STX3_chr11_59523107_ENST00000529177_MS4A15_chr11_60538763_ENST00000405633_length(transcript)=1575nt_BP=184nt
CTAGCTAGCGGCCGCCGCCCGCCGCCGCCTGCGCCTCCAGCTCCTTCGCCCCGGCGGGCCCGGCCGCCGCTTCCGGCAGCTCACCTGGGA
AGCGCTCACCTGGGACGCGCTCACCTGGGACGCGCTACCTGCCTCCGGGCGCCTGGGCTTCAGGATGAAGGACCGTCTGGAGCAGCTGAA
GGCCTTCATCATCTCCGGATCCCTCTCAGTGGCAGCCGAGAAGAACCACACCAGTTGCCTGGTGAGGAGCAGCCTGGGCACCAACATCCT
CAGCGTCATGGCGGCCTTTGCTGGGACAGCCATTCTGCTCATGGATTTTGGTGTTACCAACCGGGATGTGGACAGGGGCTATCTGGCCGT
GCTTACTATCTTCACTGTCCTGGAGTTCTTCACAGCGGTCATTGCCATGCACTTCGGGTGCCAAGCCATCCATGCCCAGGCCAGTGCACC
TGTGATCTTCCTGCCAAACGCCTTCAGCGCAGACTTCAACATCCCCAGCCCGGCAGCCTCTGCGCCCCCTGCCTATGACAATGTGGCATA
TGCCCAAGGAGTCGTCTGAGTAGCAGATGTGGCACCTGCGGGTGGAGTCCAGCCTTTTCCCTCTGGGCCCAGCCTCTCCCCACCCCCACC
TTGTTCATCAGGGGCCAGCCCCATCCCAGCTGCCCTCCCTCACCACATCTACACATACTCCGGCATCTGAGTGAAGTGTCCCCAGGGACA
TCTCTCCCACACTTTCCCCAGTGCTTTCTTTCTAAAAGACACCGGGCTGACGTCAGGGGTGTGTGTCCTTCAGCTCCCTGAGCCCTGTCA
CCCTTCCAGGACACCCACCTTGTGCATCTAAGCATTTCTCTGCTCATTGGGGAAATCCTGGCCTCATTGGAGACTCAGGTTCGAGGCCTG
CCCTGACCCTCGGGCCTCGGGAAGGTCAGAGAGCCCGGAATCCTCCAGAATGGAAGAGTCTGACTCTGGCATTCCACAGAGGTGCCGATA
CCAGGCCAAGGCCTCACAGCAGGGTAGTGGCCTGGCCGCAGGTCTCCTGGCCCCAAGATCAGCTCTGTCCTTTGTCATCTGTTGCCACAT
CCATGGAACTCAGGTTTCCTATTTGGAAACTAGAGTGTTGAACCAGATAAGGTTCATCAGGCCCTTCCAGCTCCCCAGGCTCCCTGAAGT
CCTGGGTCTAGGCCAGGCATTGTCCCCCTGCTTCCTGGAAACCCTCATTTTCCTTGTCTGTAATATGAAGTCAGCATTGGCCCCGCCCCC
CACCCCCTACCATCTCCCAATGGAGGGGAGGTTGCAGGGGAGAGCTGCCGCCAGCCCACTCCTGAGGCACCACCACAGTCAGCATCGACA
GGGGCACAGCAGTGGCAGTTTGGGACCTCCCTGTGCCTCTCAGCACTCCCTTCCCCACCCCCATAGCCCAAGGACAAGGCTACCACAGAA
GGTTACCACAGGACCTGGGCTTCGTCTCCAGGGGACAAGGAGACACTGTCAGCCTGGTGTTCACCAGGCCTGGTAGATGAGATGGCTTGT

>87814_87814_5_STX3-MS4A15_STX3_chr11_59523107_ENST00000529177_MS4A15_chr11_60538763_ENST00000405633_length(amino acids)=219AA_BP=
MGKSWPHWRLRFEACPDPRASGRSESPESSRMEESDSGIPQRCRYQAKASQQGSGLAAGLLAPRSALSFVICCHIHGTQVSYLETRVLNQ
IRFIRPFQLPRLPEVLGLGQALSPCFLETLIFLVCNMKSALAPPPTPYHLPMEGRLQGRAAASPLLRHHHSQHRQGHSSGSLGPPCASQH

--------------------------------------------------------------
>87814_87814_6_STX3-MS4A15_STX3_chr11_59523107_ENST00000529177_MS4A15_chr11_60538763_ENST00000528170_length(transcript)=643nt_BP=184nt
CTAGCTAGCGGCCGCCGCCCGCCGCCGCCTGCGCCTCCAGCTCCTTCGCCCCGGCGGGCCCGGCCGCCGCTTCCGGCAGCTCACCTGGGA
AGCGCTCACCTGGGACGCGCTCACCTGGGACGCGCTACCTGCCTCCGGGCGCCTGGGCTTCAGGATGAAGGACCGTCTGGAGCAGCTGAA
GGCCTTCATCATCTCCGGATCCCTCTCAGTGGCAGCCGAGAAGAACCACACCAGTTGCCTGGTGAGGAGCAGCCTGGGCACCAACATCCT
CAGCGTCATGGCGGCCTTTGCTGGGACAGCCATTCTGCTCATGGATTTTGGTGTTACCAACCGGGATGTGGACAGGGGCTATCTGGCCGT
GCTTACTATCTTCACTGTCCTGGAGTTCTTCACAGCGGTCATTGCCATGCACTTCGGGTGCCAAGCCATCCATGCCCAGGCCAGTGCACC
TGTGATCTTCCTGCCAAACGCCTTCAGCGCAGACTTCAACATCCCCAGCCCGGCAGCCTCTGCGCCCCCTGCCTATGACAATGTGGCATA
TGCCCAAGGAGTCGTCTGAGTAGCAGATGTGGCACCTGCGGGTGGAGTCCAGCCTTTTCCCTCTGGGCCCAGCCTCTCCCCACCCCCACC

>87814_87814_6_STX3-MS4A15_STX3_chr11_59523107_ENST00000529177_MS4A15_chr11_60538763_ENST00000528170_length(amino acids)=176AA_BP=52
MRLQLLRPGGPGRRFRQLTWEALTWDALTWDALPASGRLGFRMKDRLEQLKAFIISGSLSVAAEKNHTSCLVRSSLGTNILSVMAAFAGT

--------------------------------------------------------------
>87814_87814_7_STX3-MS4A15_STX3_chr11_59523107_ENST00000535361_MS4A15_chr11_60538763_ENST00000337911_length(transcript)=1968nt_BP=577nt
AGCTTGTCCCCGCCTAGCAAGGAGTCGGCTAAGAACTGGATCCTAGCGAGGAGCCCGGCACAGACAGCGAATGACCGCAGCCAGACAGTC
GCTCTTGCTCTTCCTCGGCCCTGCGGCAGGATCCGCCGGTGCAGGGGCCTCTCCCCGGACTCCACGCGTGTCTGGAGGGCTCTCGGGTTA
GGGAAGGGGGCTTTGGAGACGCCCCGGGCGGCCGGGCGGTGGCGGGACGCGGGCCCTTTAAGAAGGAGCGAGGGGCGCGGCCAGGTAGGG
GCGGGTCCAGGGCGGATCAGCGCTGCGCCGGCGCCGGCCCGGGAGCCGGATTTGGAGCGCGAGGCGCCGGTGGGGGCGGAGGGGGCTGCG
CGGCGGAGGCTCCCGTGGCCTCGGACGCTCCTCCTAGCTAGCGGCCGCCGCCCGCCGCCGCCTGCGCCTCCAGCTCCTTCGCCCCGGCGG
GCCCGGCCGCCGCTTCCGGCAGCTCACCTGGGAAGCGCTCACCTGGGACGCGCTCACCTGGGACGCGCTACCTGCCTCCGGGCGCCTGGG
CTTCAGGATGAAGGACCGTCTGGAGCAGCTGAAGGCCTTCATCATCTCCGGATCCCTCTCAGTGGCAGCCGAGAAGAACCACACCAGTTG
CCTGGTGAGGAGCAGCCTGGGCACCAACATCCTCAGCGTCATGGCGGCCTTTGCTGGGACAGCCATTCTGCTCATGGATTTTGGTGTTAC
CAACCGGGATGTGGACAGGGGCTATCTGGCCGTGCTTACTATCTTCACTGTCCTGGAGTTCTTCACAGCGGTCATTGCCATGCACTTCGG
GTGCCAAGCCATCCATGCCCAGGCCAGTGCACCTGTGATCTTCCTGCCAAACGCCTTCAGCGCAGACTTCAACATCCCCAGCCCGGCAGC
CTCTGCGCCCCCTGCCTATGACAATGTGGCATATGCCCAAGGAGTCGTCTGAGTAGCAGATGTGGCACCTGCGGGTGGAGTCCAGCCTTT
TCCCTCTGGGCCCAGCCTCTCCCCACCCCCACCTTGTTCATCAGGGGCCAGCCCCATCCCAGCTGCCCTCCCTCACCACATCTACACATA
CTCCGGCATCTGAGTGAAGTGTCCCCAGGGACATCTCTCCCACACTTTCCCCAGTGCTTTCTTTCTAAAAGACACCGGGCTGACGTCAGG
GGTGTGTGTCCTTCAGCTCCCTGAGCCCTGTCACCCTTCCAGGACACCCACCTTGTGCATCTAAGCATTTCTCTGCTCATTGGGGAAATC
CTGGCCTCATTGGAGACTCAGGTTCGAGGCCTGCCCTGACCCTCGGGCCTCGGGAAGGTCAGAGAGCCCGGAATCCTCCAGAATGGAAGA
GTCTGACTCTGGCATTCCACAGAGGTGCCGATACCAGGCCAAGGCCTCACAGCAGGGTAGTGGCCTGGCCGCAGGTCTCCTGGCCCCAAG
ATCAGCTCTGTCCTTTGTCATCTGTTGCCACATCCATGGAACTCAGGTTTCCTATTTGGAAACTAGAGTGTTGAACCAGATAAGGTTCAT
CAGGCCCTTCCAGCTCCCCAGGCTCCCTGAAGTCCTGGGTCTAGGCCAGGCATTGTCCCCCTGCTTCCTGGAAACCCTCATTTTCCTTGT
CTGTAATATGAAGTCAGCATTGGCCCCGCCCCCCACCCCCTACCATCTCCCAATGGAGGGGAGGTTGCAGGGGAGAGCTGCCGCCAGCCC
ACTCCTGAGGCACCACCACAGTCAGCATCGACAGGGGCACAGCAGTGGCAGTTTGGGACCTCCCTGTGCCTCTCAGCACTCCCTTCCCCA
CCCCCATAGCCCAAGGACAAGGCTACCACAGAAGGTTACCACAGGACCTGGGCTTCGTCTCCAGGGGACAAGGAGACACTGTCAGCCTGG

>87814_87814_7_STX3-MS4A15_STX3_chr11_59523107_ENST00000535361_MS4A15_chr11_60538763_ENST00000337911_length(amino acids)=305AA_BP=192
MSPPSKESAKNWILARSPAQTANDRSQTVALALPRPCGRIRRCRGLSPDSTRVWRALGLGKGALETPRAAGRWRDAGPLRRSEGRGQVGA
GPGRISAAPAPAREPDLEREAPVGAEGAARRRLPWPRTLLLASGRRPPPPAPPAPSPRRARPPLPAAHLGSAHLGRAHLGRATCLRAPGL
QDEGPSGAAEGLHHLRIPLSGSREEPHQLPGEEQPGHQHPQRHGGLCWDSHSAHGFWCYQPGCGQGLSGRAYYLHCPGVLHSGHCHALRV

--------------------------------------------------------------
>87814_87814_8_STX3-MS4A15_STX3_chr11_59523107_ENST00000535361_MS4A15_chr11_60538763_ENST00000405633_length(transcript)=1968nt_BP=577nt
AGCTTGTCCCCGCCTAGCAAGGAGTCGGCTAAGAACTGGATCCTAGCGAGGAGCCCGGCACAGACAGCGAATGACCGCAGCCAGACAGTC
GCTCTTGCTCTTCCTCGGCCCTGCGGCAGGATCCGCCGGTGCAGGGGCCTCTCCCCGGACTCCACGCGTGTCTGGAGGGCTCTCGGGTTA
GGGAAGGGGGCTTTGGAGACGCCCCGGGCGGCCGGGCGGTGGCGGGACGCGGGCCCTTTAAGAAGGAGCGAGGGGCGCGGCCAGGTAGGG
GCGGGTCCAGGGCGGATCAGCGCTGCGCCGGCGCCGGCCCGGGAGCCGGATTTGGAGCGCGAGGCGCCGGTGGGGGCGGAGGGGGCTGCG
CGGCGGAGGCTCCCGTGGCCTCGGACGCTCCTCCTAGCTAGCGGCCGCCGCCCGCCGCCGCCTGCGCCTCCAGCTCCTTCGCCCCGGCGG
GCCCGGCCGCCGCTTCCGGCAGCTCACCTGGGAAGCGCTCACCTGGGACGCGCTCACCTGGGACGCGCTACCTGCCTCCGGGCGCCTGGG
CTTCAGGATGAAGGACCGTCTGGAGCAGCTGAAGGCCTTCATCATCTCCGGATCCCTCTCAGTGGCAGCCGAGAAGAACCACACCAGTTG
CCTGGTGAGGAGCAGCCTGGGCACCAACATCCTCAGCGTCATGGCGGCCTTTGCTGGGACAGCCATTCTGCTCATGGATTTTGGTGTTAC
CAACCGGGATGTGGACAGGGGCTATCTGGCCGTGCTTACTATCTTCACTGTCCTGGAGTTCTTCACAGCGGTCATTGCCATGCACTTCGG
GTGCCAAGCCATCCATGCCCAGGCCAGTGCACCTGTGATCTTCCTGCCAAACGCCTTCAGCGCAGACTTCAACATCCCCAGCCCGGCAGC
CTCTGCGCCCCCTGCCTATGACAATGTGGCATATGCCCAAGGAGTCGTCTGAGTAGCAGATGTGGCACCTGCGGGTGGAGTCCAGCCTTT
TCCCTCTGGGCCCAGCCTCTCCCCACCCCCACCTTGTTCATCAGGGGCCAGCCCCATCCCAGCTGCCCTCCCTCACCACATCTACACATA
CTCCGGCATCTGAGTGAAGTGTCCCCAGGGACATCTCTCCCACACTTTCCCCAGTGCTTTCTTTCTAAAAGACACCGGGCTGACGTCAGG
GGTGTGTGTCCTTCAGCTCCCTGAGCCCTGTCACCCTTCCAGGACACCCACCTTGTGCATCTAAGCATTTCTCTGCTCATTGGGGAAATC
CTGGCCTCATTGGAGACTCAGGTTCGAGGCCTGCCCTGACCCTCGGGCCTCGGGAAGGTCAGAGAGCCCGGAATCCTCCAGAATGGAAGA
GTCTGACTCTGGCATTCCACAGAGGTGCCGATACCAGGCCAAGGCCTCACAGCAGGGTAGTGGCCTGGCCGCAGGTCTCCTGGCCCCAAG
ATCAGCTCTGTCCTTTGTCATCTGTTGCCACATCCATGGAACTCAGGTTTCCTATTTGGAAACTAGAGTGTTGAACCAGATAAGGTTCAT
CAGGCCCTTCCAGCTCCCCAGGCTCCCTGAAGTCCTGGGTCTAGGCCAGGCATTGTCCCCCTGCTTCCTGGAAACCCTCATTTTCCTTGT
CTGTAATATGAAGTCAGCATTGGCCCCGCCCCCCACCCCCTACCATCTCCCAATGGAGGGGAGGTTGCAGGGGAGAGCTGCCGCCAGCCC
ACTCCTGAGGCACCACCACAGTCAGCATCGACAGGGGCACAGCAGTGGCAGTTTGGGACCTCCCTGTGCCTCTCAGCACTCCCTTCCCCA
CCCCCATAGCCCAAGGACAAGGCTACCACAGAAGGTTACCACAGGACCTGGGCTTCGTCTCCAGGGGACAAGGAGACACTGTCAGCCTGG

>87814_87814_8_STX3-MS4A15_STX3_chr11_59523107_ENST00000535361_MS4A15_chr11_60538763_ENST00000405633_length(amino acids)=305AA_BP=192
MSPPSKESAKNWILARSPAQTANDRSQTVALALPRPCGRIRRCRGLSPDSTRVWRALGLGKGALETPRAAGRWRDAGPLRRSEGRGQVGA
GPGRISAAPAPAREPDLEREAPVGAEGAARRRLPWPRTLLLASGRRPPPPAPPAPSPRRARPPLPAAHLGSAHLGRAHLGRATCLRAPGL
QDEGPSGAAEGLHHLRIPLSGSREEPHQLPGEEQPGHQHPQRHGGLCWDSHSAHGFWCYQPGCGQGLSGRAYYLHCPGVLHSGHCHALRV

--------------------------------------------------------------
>87814_87814_9_STX3-MS4A15_STX3_chr11_59523107_ENST00000535361_MS4A15_chr11_60538763_ENST00000528170_length(transcript)=1036nt_BP=577nt
AGCTTGTCCCCGCCTAGCAAGGAGTCGGCTAAGAACTGGATCCTAGCGAGGAGCCCGGCACAGACAGCGAATGACCGCAGCCAGACAGTC
GCTCTTGCTCTTCCTCGGCCCTGCGGCAGGATCCGCCGGTGCAGGGGCCTCTCCCCGGACTCCACGCGTGTCTGGAGGGCTCTCGGGTTA
GGGAAGGGGGCTTTGGAGACGCCCCGGGCGGCCGGGCGGTGGCGGGACGCGGGCCCTTTAAGAAGGAGCGAGGGGCGCGGCCAGGTAGGG
GCGGGTCCAGGGCGGATCAGCGCTGCGCCGGCGCCGGCCCGGGAGCCGGATTTGGAGCGCGAGGCGCCGGTGGGGGCGGAGGGGGCTGCG
CGGCGGAGGCTCCCGTGGCCTCGGACGCTCCTCCTAGCTAGCGGCCGCCGCCCGCCGCCGCCTGCGCCTCCAGCTCCTTCGCCCCGGCGG
GCCCGGCCGCCGCTTCCGGCAGCTCACCTGGGAAGCGCTCACCTGGGACGCGCTCACCTGGGACGCGCTACCTGCCTCCGGGCGCCTGGG
CTTCAGGATGAAGGACCGTCTGGAGCAGCTGAAGGCCTTCATCATCTCCGGATCCCTCTCAGTGGCAGCCGAGAAGAACCACACCAGTTG
CCTGGTGAGGAGCAGCCTGGGCACCAACATCCTCAGCGTCATGGCGGCCTTTGCTGGGACAGCCATTCTGCTCATGGATTTTGGTGTTAC
CAACCGGGATGTGGACAGGGGCTATCTGGCCGTGCTTACTATCTTCACTGTCCTGGAGTTCTTCACAGCGGTCATTGCCATGCACTTCGG
GTGCCAAGCCATCCATGCCCAGGCCAGTGCACCTGTGATCTTCCTGCCAAACGCCTTCAGCGCAGACTTCAACATCCCCAGCCCGGCAGC
CTCTGCGCCCCCTGCCTATGACAATGTGGCATATGCCCAAGGAGTCGTCTGAGTAGCAGATGTGGCACCTGCGGGTGGAGTCCAGCCTTT

>87814_87814_9_STX3-MS4A15_STX3_chr11_59523107_ENST00000535361_MS4A15_chr11_60538763_ENST00000528170_length(amino acids)=305AA_BP=192
MSPPSKESAKNWILARSPAQTANDRSQTVALALPRPCGRIRRCRGLSPDSTRVWRALGLGKGALETPRAAGRWRDAGPLRRSEGRGQVGA
GPGRISAAPAPAREPDLEREAPVGAEGAARRRLPWPRTLLLASGRRPPPPAPPAPSPRRARPPLPAAHLGSAHLGRAHLGRATCLRAPGL
QDEGPSGAAEGLHHLRIPLSGSREEPHQLPGEEQPGHQHPQRHGGLCWDSHSAHGFWCYQPGCGQGLSGRAYYLHCPGVLHSGHCHALRV

--------------------------------------------------------------
>87814_87814_10_STX3-MS4A15_STX3_chr11_59523108_ENST00000337979_MS4A15_chr11_60538764_ENST00000337911_length(transcript)=1968nt_BP=577nt
AGCTTGTCCCCGCCTAGCAAGGAGTCGGCTAAGAACTGGATCCTAGCGAGGAGCCCGGCACAGACAGCGAATGACCGCAGCCAGACAGTC
GCTCTTGCTCTTCCTCGGCCCTGCGGCAGGATCCGCCGGTGCAGGGGCCTCTCCCCGGACTCCACGCGTGTCTGGAGGGCTCTCGGGTTA
GGGAAGGGGGCTTTGGAGACGCCCCGGGCGGCCGGGCGGTGGCGGGACGCGGGCCCTTTAAGAAGGAGCGAGGGGCGCGGCCAGGTAGGG
GCGGGTCCAGGGCGGATCAGCGCTGCGCCGGCGCCGGCCCGGGAGCCGGATTTGGAGCGCGAGGCGCCGGTGGGGGCGGAGGGGGCTGCG
CGGCGGAGGCTCCCGTGGCCTCGGACGCTCCTCCTAGCTAGCGGCCGCCGCCCGCCGCCGCCTGCGCCTCCAGCTCCTTCGCCCCGGCGG
GCCCGGCCGCCGCTTCCGGCAGCTCACCTGGGAAGCGCTCACCTGGGACGCGCTCACCTGGGACGCGCTACCTGCCTCCGGGCGCCTGGG
CTTCAGGATGAAGGACCGTCTGGAGCAGCTGAAGGCCTTCATCATCTCCGGATCCCTCTCAGTGGCAGCCGAGAAGAACCACACCAGTTG
CCTGGTGAGGAGCAGCCTGGGCACCAACATCCTCAGCGTCATGGCGGCCTTTGCTGGGACAGCCATTCTGCTCATGGATTTTGGTGTTAC
CAACCGGGATGTGGACAGGGGCTATCTGGCCGTGCTTACTATCTTCACTGTCCTGGAGTTCTTCACAGCGGTCATTGCCATGCACTTCGG
GTGCCAAGCCATCCATGCCCAGGCCAGTGCACCTGTGATCTTCCTGCCAAACGCCTTCAGCGCAGACTTCAACATCCCCAGCCCGGCAGC
CTCTGCGCCCCCTGCCTATGACAATGTGGCATATGCCCAAGGAGTCGTCTGAGTAGCAGATGTGGCACCTGCGGGTGGAGTCCAGCCTTT
TCCCTCTGGGCCCAGCCTCTCCCCACCCCCACCTTGTTCATCAGGGGCCAGCCCCATCCCAGCTGCCCTCCCTCACCACATCTACACATA
CTCCGGCATCTGAGTGAAGTGTCCCCAGGGACATCTCTCCCACACTTTCCCCAGTGCTTTCTTTCTAAAAGACACCGGGCTGACGTCAGG
GGTGTGTGTCCTTCAGCTCCCTGAGCCCTGTCACCCTTCCAGGACACCCACCTTGTGCATCTAAGCATTTCTCTGCTCATTGGGGAAATC
CTGGCCTCATTGGAGACTCAGGTTCGAGGCCTGCCCTGACCCTCGGGCCTCGGGAAGGTCAGAGAGCCCGGAATCCTCCAGAATGGAAGA
GTCTGACTCTGGCATTCCACAGAGGTGCCGATACCAGGCCAAGGCCTCACAGCAGGGTAGTGGCCTGGCCGCAGGTCTCCTGGCCCCAAG
ATCAGCTCTGTCCTTTGTCATCTGTTGCCACATCCATGGAACTCAGGTTTCCTATTTGGAAACTAGAGTGTTGAACCAGATAAGGTTCAT
CAGGCCCTTCCAGCTCCCCAGGCTCCCTGAAGTCCTGGGTCTAGGCCAGGCATTGTCCCCCTGCTTCCTGGAAACCCTCATTTTCCTTGT
CTGTAATATGAAGTCAGCATTGGCCCCGCCCCCCACCCCCTACCATCTCCCAATGGAGGGGAGGTTGCAGGGGAGAGCTGCCGCCAGCCC
ACTCCTGAGGCACCACCACAGTCAGCATCGACAGGGGCACAGCAGTGGCAGTTTGGGACCTCCCTGTGCCTCTCAGCACTCCCTTCCCCA
CCCCCATAGCCCAAGGACAAGGCTACCACAGAAGGTTACCACAGGACCTGGGCTTCGTCTCCAGGGGACAAGGAGACACTGTCAGCCTGG

>87814_87814_10_STX3-MS4A15_STX3_chr11_59523108_ENST00000337979_MS4A15_chr11_60538764_ENST00000337911_length(amino acids)=305AA_BP=192
MSPPSKESAKNWILARSPAQTANDRSQTVALALPRPCGRIRRCRGLSPDSTRVWRALGLGKGALETPRAAGRWRDAGPLRRSEGRGQVGA
GPGRISAAPAPAREPDLEREAPVGAEGAARRRLPWPRTLLLASGRRPPPPAPPAPSPRRARPPLPAAHLGSAHLGRAHLGRATCLRAPGL
QDEGPSGAAEGLHHLRIPLSGSREEPHQLPGEEQPGHQHPQRHGGLCWDSHSAHGFWCYQPGCGQGLSGRAYYLHCPGVLHSGHCHALRV

--------------------------------------------------------------
>87814_87814_11_STX3-MS4A15_STX3_chr11_59523108_ENST00000337979_MS4A15_chr11_60538764_ENST00000405633_length(transcript)=1968nt_BP=577nt
AGCTTGTCCCCGCCTAGCAAGGAGTCGGCTAAGAACTGGATCCTAGCGAGGAGCCCGGCACAGACAGCGAATGACCGCAGCCAGACAGTC
GCTCTTGCTCTTCCTCGGCCCTGCGGCAGGATCCGCCGGTGCAGGGGCCTCTCCCCGGACTCCACGCGTGTCTGGAGGGCTCTCGGGTTA
GGGAAGGGGGCTTTGGAGACGCCCCGGGCGGCCGGGCGGTGGCGGGACGCGGGCCCTTTAAGAAGGAGCGAGGGGCGCGGCCAGGTAGGG
GCGGGTCCAGGGCGGATCAGCGCTGCGCCGGCGCCGGCCCGGGAGCCGGATTTGGAGCGCGAGGCGCCGGTGGGGGCGGAGGGGGCTGCG
CGGCGGAGGCTCCCGTGGCCTCGGACGCTCCTCCTAGCTAGCGGCCGCCGCCCGCCGCCGCCTGCGCCTCCAGCTCCTTCGCCCCGGCGG
GCCCGGCCGCCGCTTCCGGCAGCTCACCTGGGAAGCGCTCACCTGGGACGCGCTCACCTGGGACGCGCTACCTGCCTCCGGGCGCCTGGG
CTTCAGGATGAAGGACCGTCTGGAGCAGCTGAAGGCCTTCATCATCTCCGGATCCCTCTCAGTGGCAGCCGAGAAGAACCACACCAGTTG
CCTGGTGAGGAGCAGCCTGGGCACCAACATCCTCAGCGTCATGGCGGCCTTTGCTGGGACAGCCATTCTGCTCATGGATTTTGGTGTTAC
CAACCGGGATGTGGACAGGGGCTATCTGGCCGTGCTTACTATCTTCACTGTCCTGGAGTTCTTCACAGCGGTCATTGCCATGCACTTCGG
GTGCCAAGCCATCCATGCCCAGGCCAGTGCACCTGTGATCTTCCTGCCAAACGCCTTCAGCGCAGACTTCAACATCCCCAGCCCGGCAGC
CTCTGCGCCCCCTGCCTATGACAATGTGGCATATGCCCAAGGAGTCGTCTGAGTAGCAGATGTGGCACCTGCGGGTGGAGTCCAGCCTTT
TCCCTCTGGGCCCAGCCTCTCCCCACCCCCACCTTGTTCATCAGGGGCCAGCCCCATCCCAGCTGCCCTCCCTCACCACATCTACACATA
CTCCGGCATCTGAGTGAAGTGTCCCCAGGGACATCTCTCCCACACTTTCCCCAGTGCTTTCTTTCTAAAAGACACCGGGCTGACGTCAGG
GGTGTGTGTCCTTCAGCTCCCTGAGCCCTGTCACCCTTCCAGGACACCCACCTTGTGCATCTAAGCATTTCTCTGCTCATTGGGGAAATC
CTGGCCTCATTGGAGACTCAGGTTCGAGGCCTGCCCTGACCCTCGGGCCTCGGGAAGGTCAGAGAGCCCGGAATCCTCCAGAATGGAAGA
GTCTGACTCTGGCATTCCACAGAGGTGCCGATACCAGGCCAAGGCCTCACAGCAGGGTAGTGGCCTGGCCGCAGGTCTCCTGGCCCCAAG
ATCAGCTCTGTCCTTTGTCATCTGTTGCCACATCCATGGAACTCAGGTTTCCTATTTGGAAACTAGAGTGTTGAACCAGATAAGGTTCAT
CAGGCCCTTCCAGCTCCCCAGGCTCCCTGAAGTCCTGGGTCTAGGCCAGGCATTGTCCCCCTGCTTCCTGGAAACCCTCATTTTCCTTGT
CTGTAATATGAAGTCAGCATTGGCCCCGCCCCCCACCCCCTACCATCTCCCAATGGAGGGGAGGTTGCAGGGGAGAGCTGCCGCCAGCCC
ACTCCTGAGGCACCACCACAGTCAGCATCGACAGGGGCACAGCAGTGGCAGTTTGGGACCTCCCTGTGCCTCTCAGCACTCCCTTCCCCA
CCCCCATAGCCCAAGGACAAGGCTACCACAGAAGGTTACCACAGGACCTGGGCTTCGTCTCCAGGGGACAAGGAGACACTGTCAGCCTGG

>87814_87814_11_STX3-MS4A15_STX3_chr11_59523108_ENST00000337979_MS4A15_chr11_60538764_ENST00000405633_length(amino acids)=305AA_BP=192
MSPPSKESAKNWILARSPAQTANDRSQTVALALPRPCGRIRRCRGLSPDSTRVWRALGLGKGALETPRAAGRWRDAGPLRRSEGRGQVGA
GPGRISAAPAPAREPDLEREAPVGAEGAARRRLPWPRTLLLASGRRPPPPAPPAPSPRRARPPLPAAHLGSAHLGRAHLGRATCLRAPGL
QDEGPSGAAEGLHHLRIPLSGSREEPHQLPGEEQPGHQHPQRHGGLCWDSHSAHGFWCYQPGCGQGLSGRAYYLHCPGVLHSGHCHALRV

--------------------------------------------------------------
>87814_87814_12_STX3-MS4A15_STX3_chr11_59523108_ENST00000337979_MS4A15_chr11_60538764_ENST00000528170_length(transcript)=1036nt_BP=577nt
AGCTTGTCCCCGCCTAGCAAGGAGTCGGCTAAGAACTGGATCCTAGCGAGGAGCCCGGCACAGACAGCGAATGACCGCAGCCAGACAGTC
GCTCTTGCTCTTCCTCGGCCCTGCGGCAGGATCCGCCGGTGCAGGGGCCTCTCCCCGGACTCCACGCGTGTCTGGAGGGCTCTCGGGTTA
GGGAAGGGGGCTTTGGAGACGCCCCGGGCGGCCGGGCGGTGGCGGGACGCGGGCCCTTTAAGAAGGAGCGAGGGGCGCGGCCAGGTAGGG
GCGGGTCCAGGGCGGATCAGCGCTGCGCCGGCGCCGGCCCGGGAGCCGGATTTGGAGCGCGAGGCGCCGGTGGGGGCGGAGGGGGCTGCG
CGGCGGAGGCTCCCGTGGCCTCGGACGCTCCTCCTAGCTAGCGGCCGCCGCCCGCCGCCGCCTGCGCCTCCAGCTCCTTCGCCCCGGCGG
GCCCGGCCGCCGCTTCCGGCAGCTCACCTGGGAAGCGCTCACCTGGGACGCGCTCACCTGGGACGCGCTACCTGCCTCCGGGCGCCTGGG
CTTCAGGATGAAGGACCGTCTGGAGCAGCTGAAGGCCTTCATCATCTCCGGATCCCTCTCAGTGGCAGCCGAGAAGAACCACACCAGTTG
CCTGGTGAGGAGCAGCCTGGGCACCAACATCCTCAGCGTCATGGCGGCCTTTGCTGGGACAGCCATTCTGCTCATGGATTTTGGTGTTAC
CAACCGGGATGTGGACAGGGGCTATCTGGCCGTGCTTACTATCTTCACTGTCCTGGAGTTCTTCACAGCGGTCATTGCCATGCACTTCGG
GTGCCAAGCCATCCATGCCCAGGCCAGTGCACCTGTGATCTTCCTGCCAAACGCCTTCAGCGCAGACTTCAACATCCCCAGCCCGGCAGC
CTCTGCGCCCCCTGCCTATGACAATGTGGCATATGCCCAAGGAGTCGTCTGAGTAGCAGATGTGGCACCTGCGGGTGGAGTCCAGCCTTT

>87814_87814_12_STX3-MS4A15_STX3_chr11_59523108_ENST00000337979_MS4A15_chr11_60538764_ENST00000528170_length(amino acids)=305AA_BP=192
MSPPSKESAKNWILARSPAQTANDRSQTVALALPRPCGRIRRCRGLSPDSTRVWRALGLGKGALETPRAAGRWRDAGPLRRSEGRGQVGA
GPGRISAAPAPAREPDLEREAPVGAEGAARRRLPWPRTLLLASGRRPPPPAPPAPSPRRARPPLPAAHLGSAHLGRAHLGRATCLRAPGL
QDEGPSGAAEGLHHLRIPLSGSREEPHQLPGEEQPGHQHPQRHGGLCWDSHSAHGFWCYQPGCGQGLSGRAYYLHCPGVLHSGHCHALRV

--------------------------------------------------------------
>87814_87814_13_STX3-MS4A15_STX3_chr11_59523108_ENST00000529177_MS4A15_chr11_60538764_ENST00000337911_length(transcript)=1575nt_BP=184nt
CTAGCTAGCGGCCGCCGCCCGCCGCCGCCTGCGCCTCCAGCTCCTTCGCCCCGGCGGGCCCGGCCGCCGCTTCCGGCAGCTCACCTGGGA
AGCGCTCACCTGGGACGCGCTCACCTGGGACGCGCTACCTGCCTCCGGGCGCCTGGGCTTCAGGATGAAGGACCGTCTGGAGCAGCTGAA
GGCCTTCATCATCTCCGGATCCCTCTCAGTGGCAGCCGAGAAGAACCACACCAGTTGCCTGGTGAGGAGCAGCCTGGGCACCAACATCCT
CAGCGTCATGGCGGCCTTTGCTGGGACAGCCATTCTGCTCATGGATTTTGGTGTTACCAACCGGGATGTGGACAGGGGCTATCTGGCCGT
GCTTACTATCTTCACTGTCCTGGAGTTCTTCACAGCGGTCATTGCCATGCACTTCGGGTGCCAAGCCATCCATGCCCAGGCCAGTGCACC
TGTGATCTTCCTGCCAAACGCCTTCAGCGCAGACTTCAACATCCCCAGCCCGGCAGCCTCTGCGCCCCCTGCCTATGACAATGTGGCATA
TGCCCAAGGAGTCGTCTGAGTAGCAGATGTGGCACCTGCGGGTGGAGTCCAGCCTTTTCCCTCTGGGCCCAGCCTCTCCCCACCCCCACC
TTGTTCATCAGGGGCCAGCCCCATCCCAGCTGCCCTCCCTCACCACATCTACACATACTCCGGCATCTGAGTGAAGTGTCCCCAGGGACA
TCTCTCCCACACTTTCCCCAGTGCTTTCTTTCTAAAAGACACCGGGCTGACGTCAGGGGTGTGTGTCCTTCAGCTCCCTGAGCCCTGTCA
CCCTTCCAGGACACCCACCTTGTGCATCTAAGCATTTCTCTGCTCATTGGGGAAATCCTGGCCTCATTGGAGACTCAGGTTCGAGGCCTG
CCCTGACCCTCGGGCCTCGGGAAGGTCAGAGAGCCCGGAATCCTCCAGAATGGAAGAGTCTGACTCTGGCATTCCACAGAGGTGCCGATA
CCAGGCCAAGGCCTCACAGCAGGGTAGTGGCCTGGCCGCAGGTCTCCTGGCCCCAAGATCAGCTCTGTCCTTTGTCATCTGTTGCCACAT
CCATGGAACTCAGGTTTCCTATTTGGAAACTAGAGTGTTGAACCAGATAAGGTTCATCAGGCCCTTCCAGCTCCCCAGGCTCCCTGAAGT
CCTGGGTCTAGGCCAGGCATTGTCCCCCTGCTTCCTGGAAACCCTCATTTTCCTTGTCTGTAATATGAAGTCAGCATTGGCCCCGCCCCC
CACCCCCTACCATCTCCCAATGGAGGGGAGGTTGCAGGGGAGAGCTGCCGCCAGCCCACTCCTGAGGCACCACCACAGTCAGCATCGACA
GGGGCACAGCAGTGGCAGTTTGGGACCTCCCTGTGCCTCTCAGCACTCCCTTCCCCACCCCCATAGCCCAAGGACAAGGCTACCACAGAA
GGTTACCACAGGACCTGGGCTTCGTCTCCAGGGGACAAGGAGACACTGTCAGCCTGGTGTTCACCAGGCCTGGTAGATGAGATGGCTTGT

>87814_87814_13_STX3-MS4A15_STX3_chr11_59523108_ENST00000529177_MS4A15_chr11_60538764_ENST00000337911_length(amino acids)=219AA_BP=
MGKSWPHWRLRFEACPDPRASGRSESPESSRMEESDSGIPQRCRYQAKASQQGSGLAAGLLAPRSALSFVICCHIHGTQVSYLETRVLNQ
IRFIRPFQLPRLPEVLGLGQALSPCFLETLIFLVCNMKSALAPPPTPYHLPMEGRLQGRAAASPLLRHHHSQHRQGHSSGSLGPPCASQH

--------------------------------------------------------------
>87814_87814_14_STX3-MS4A15_STX3_chr11_59523108_ENST00000529177_MS4A15_chr11_60538764_ENST00000405633_length(transcript)=1575nt_BP=184nt
CTAGCTAGCGGCCGCCGCCCGCCGCCGCCTGCGCCTCCAGCTCCTTCGCCCCGGCGGGCCCGGCCGCCGCTTCCGGCAGCTCACCTGGGA
AGCGCTCACCTGGGACGCGCTCACCTGGGACGCGCTACCTGCCTCCGGGCGCCTGGGCTTCAGGATGAAGGACCGTCTGGAGCAGCTGAA
GGCCTTCATCATCTCCGGATCCCTCTCAGTGGCAGCCGAGAAGAACCACACCAGTTGCCTGGTGAGGAGCAGCCTGGGCACCAACATCCT
CAGCGTCATGGCGGCCTTTGCTGGGACAGCCATTCTGCTCATGGATTTTGGTGTTACCAACCGGGATGTGGACAGGGGCTATCTGGCCGT
GCTTACTATCTTCACTGTCCTGGAGTTCTTCACAGCGGTCATTGCCATGCACTTCGGGTGCCAAGCCATCCATGCCCAGGCCAGTGCACC
TGTGATCTTCCTGCCAAACGCCTTCAGCGCAGACTTCAACATCCCCAGCCCGGCAGCCTCTGCGCCCCCTGCCTATGACAATGTGGCATA
TGCCCAAGGAGTCGTCTGAGTAGCAGATGTGGCACCTGCGGGTGGAGTCCAGCCTTTTCCCTCTGGGCCCAGCCTCTCCCCACCCCCACC
TTGTTCATCAGGGGCCAGCCCCATCCCAGCTGCCCTCCCTCACCACATCTACACATACTCCGGCATCTGAGTGAAGTGTCCCCAGGGACA
TCTCTCCCACACTTTCCCCAGTGCTTTCTTTCTAAAAGACACCGGGCTGACGTCAGGGGTGTGTGTCCTTCAGCTCCCTGAGCCCTGTCA
CCCTTCCAGGACACCCACCTTGTGCATCTAAGCATTTCTCTGCTCATTGGGGAAATCCTGGCCTCATTGGAGACTCAGGTTCGAGGCCTG
CCCTGACCCTCGGGCCTCGGGAAGGTCAGAGAGCCCGGAATCCTCCAGAATGGAAGAGTCTGACTCTGGCATTCCACAGAGGTGCCGATA
CCAGGCCAAGGCCTCACAGCAGGGTAGTGGCCTGGCCGCAGGTCTCCTGGCCCCAAGATCAGCTCTGTCCTTTGTCATCTGTTGCCACAT
CCATGGAACTCAGGTTTCCTATTTGGAAACTAGAGTGTTGAACCAGATAAGGTTCATCAGGCCCTTCCAGCTCCCCAGGCTCCCTGAAGT
CCTGGGTCTAGGCCAGGCATTGTCCCCCTGCTTCCTGGAAACCCTCATTTTCCTTGTCTGTAATATGAAGTCAGCATTGGCCCCGCCCCC
CACCCCCTACCATCTCCCAATGGAGGGGAGGTTGCAGGGGAGAGCTGCCGCCAGCCCACTCCTGAGGCACCACCACAGTCAGCATCGACA
GGGGCACAGCAGTGGCAGTTTGGGACCTCCCTGTGCCTCTCAGCACTCCCTTCCCCACCCCCATAGCCCAAGGACAAGGCTACCACAGAA
GGTTACCACAGGACCTGGGCTTCGTCTCCAGGGGACAAGGAGACACTGTCAGCCTGGTGTTCACCAGGCCTGGTAGATGAGATGGCTTGT

>87814_87814_14_STX3-MS4A15_STX3_chr11_59523108_ENST00000529177_MS4A15_chr11_60538764_ENST00000405633_length(amino acids)=219AA_BP=
MGKSWPHWRLRFEACPDPRASGRSESPESSRMEESDSGIPQRCRYQAKASQQGSGLAAGLLAPRSALSFVICCHIHGTQVSYLETRVLNQ
IRFIRPFQLPRLPEVLGLGQALSPCFLETLIFLVCNMKSALAPPPTPYHLPMEGRLQGRAAASPLLRHHHSQHRQGHSSGSLGPPCASQH

--------------------------------------------------------------
>87814_87814_15_STX3-MS4A15_STX3_chr11_59523108_ENST00000529177_MS4A15_chr11_60538764_ENST00000528170_length(transcript)=643nt_BP=184nt
CTAGCTAGCGGCCGCCGCCCGCCGCCGCCTGCGCCTCCAGCTCCTTCGCCCCGGCGGGCCCGGCCGCCGCTTCCGGCAGCTCACCTGGGA
AGCGCTCACCTGGGACGCGCTCACCTGGGACGCGCTACCTGCCTCCGGGCGCCTGGGCTTCAGGATGAAGGACCGTCTGGAGCAGCTGAA
GGCCTTCATCATCTCCGGATCCCTCTCAGTGGCAGCCGAGAAGAACCACACCAGTTGCCTGGTGAGGAGCAGCCTGGGCACCAACATCCT
CAGCGTCATGGCGGCCTTTGCTGGGACAGCCATTCTGCTCATGGATTTTGGTGTTACCAACCGGGATGTGGACAGGGGCTATCTGGCCGT
GCTTACTATCTTCACTGTCCTGGAGTTCTTCACAGCGGTCATTGCCATGCACTTCGGGTGCCAAGCCATCCATGCCCAGGCCAGTGCACC
TGTGATCTTCCTGCCAAACGCCTTCAGCGCAGACTTCAACATCCCCAGCCCGGCAGCCTCTGCGCCCCCTGCCTATGACAATGTGGCATA
TGCCCAAGGAGTCGTCTGAGTAGCAGATGTGGCACCTGCGGGTGGAGTCCAGCCTTTTCCCTCTGGGCCCAGCCTCTCCCCACCCCCACC

>87814_87814_15_STX3-MS4A15_STX3_chr11_59523108_ENST00000529177_MS4A15_chr11_60538764_ENST00000528170_length(amino acids)=176AA_BP=52
MRLQLLRPGGPGRRFRQLTWEALTWDALTWDALPASGRLGFRMKDRLEQLKAFIISGSLSVAAEKNHTSCLVRSSLGTNILSVMAAFAGT

--------------------------------------------------------------
>87814_87814_16_STX3-MS4A15_STX3_chr11_59523108_ENST00000535361_MS4A15_chr11_60538764_ENST00000337911_length(transcript)=1968nt_BP=577nt
AGCTTGTCCCCGCCTAGCAAGGAGTCGGCTAAGAACTGGATCCTAGCGAGGAGCCCGGCACAGACAGCGAATGACCGCAGCCAGACAGTC
GCTCTTGCTCTTCCTCGGCCCTGCGGCAGGATCCGCCGGTGCAGGGGCCTCTCCCCGGACTCCACGCGTGTCTGGAGGGCTCTCGGGTTA
GGGAAGGGGGCTTTGGAGACGCCCCGGGCGGCCGGGCGGTGGCGGGACGCGGGCCCTTTAAGAAGGAGCGAGGGGCGCGGCCAGGTAGGG
GCGGGTCCAGGGCGGATCAGCGCTGCGCCGGCGCCGGCCCGGGAGCCGGATTTGGAGCGCGAGGCGCCGGTGGGGGCGGAGGGGGCTGCG
CGGCGGAGGCTCCCGTGGCCTCGGACGCTCCTCCTAGCTAGCGGCCGCCGCCCGCCGCCGCCTGCGCCTCCAGCTCCTTCGCCCCGGCGG
GCCCGGCCGCCGCTTCCGGCAGCTCACCTGGGAAGCGCTCACCTGGGACGCGCTCACCTGGGACGCGCTACCTGCCTCCGGGCGCCTGGG
CTTCAGGATGAAGGACCGTCTGGAGCAGCTGAAGGCCTTCATCATCTCCGGATCCCTCTCAGTGGCAGCCGAGAAGAACCACACCAGTTG
CCTGGTGAGGAGCAGCCTGGGCACCAACATCCTCAGCGTCATGGCGGCCTTTGCTGGGACAGCCATTCTGCTCATGGATTTTGGTGTTAC
CAACCGGGATGTGGACAGGGGCTATCTGGCCGTGCTTACTATCTTCACTGTCCTGGAGTTCTTCACAGCGGTCATTGCCATGCACTTCGG
GTGCCAAGCCATCCATGCCCAGGCCAGTGCACCTGTGATCTTCCTGCCAAACGCCTTCAGCGCAGACTTCAACATCCCCAGCCCGGCAGC
CTCTGCGCCCCCTGCCTATGACAATGTGGCATATGCCCAAGGAGTCGTCTGAGTAGCAGATGTGGCACCTGCGGGTGGAGTCCAGCCTTT
TCCCTCTGGGCCCAGCCTCTCCCCACCCCCACCTTGTTCATCAGGGGCCAGCCCCATCCCAGCTGCCCTCCCTCACCACATCTACACATA
CTCCGGCATCTGAGTGAAGTGTCCCCAGGGACATCTCTCCCACACTTTCCCCAGTGCTTTCTTTCTAAAAGACACCGGGCTGACGTCAGG
GGTGTGTGTCCTTCAGCTCCCTGAGCCCTGTCACCCTTCCAGGACACCCACCTTGTGCATCTAAGCATTTCTCTGCTCATTGGGGAAATC
CTGGCCTCATTGGAGACTCAGGTTCGAGGCCTGCCCTGACCCTCGGGCCTCGGGAAGGTCAGAGAGCCCGGAATCCTCCAGAATGGAAGA
GTCTGACTCTGGCATTCCACAGAGGTGCCGATACCAGGCCAAGGCCTCACAGCAGGGTAGTGGCCTGGCCGCAGGTCTCCTGGCCCCAAG
ATCAGCTCTGTCCTTTGTCATCTGTTGCCACATCCATGGAACTCAGGTTTCCTATTTGGAAACTAGAGTGTTGAACCAGATAAGGTTCAT
CAGGCCCTTCCAGCTCCCCAGGCTCCCTGAAGTCCTGGGTCTAGGCCAGGCATTGTCCCCCTGCTTCCTGGAAACCCTCATTTTCCTTGT
CTGTAATATGAAGTCAGCATTGGCCCCGCCCCCCACCCCCTACCATCTCCCAATGGAGGGGAGGTTGCAGGGGAGAGCTGCCGCCAGCCC
ACTCCTGAGGCACCACCACAGTCAGCATCGACAGGGGCACAGCAGTGGCAGTTTGGGACCTCCCTGTGCCTCTCAGCACTCCCTTCCCCA
CCCCCATAGCCCAAGGACAAGGCTACCACAGAAGGTTACCACAGGACCTGGGCTTCGTCTCCAGGGGACAAGGAGACACTGTCAGCCTGG

>87814_87814_16_STX3-MS4A15_STX3_chr11_59523108_ENST00000535361_MS4A15_chr11_60538764_ENST00000337911_length(amino acids)=305AA_BP=192
MSPPSKESAKNWILARSPAQTANDRSQTVALALPRPCGRIRRCRGLSPDSTRVWRALGLGKGALETPRAAGRWRDAGPLRRSEGRGQVGA
GPGRISAAPAPAREPDLEREAPVGAEGAARRRLPWPRTLLLASGRRPPPPAPPAPSPRRARPPLPAAHLGSAHLGRAHLGRATCLRAPGL
QDEGPSGAAEGLHHLRIPLSGSREEPHQLPGEEQPGHQHPQRHGGLCWDSHSAHGFWCYQPGCGQGLSGRAYYLHCPGVLHSGHCHALRV

--------------------------------------------------------------
>87814_87814_17_STX3-MS4A15_STX3_chr11_59523108_ENST00000535361_MS4A15_chr11_60538764_ENST00000405633_length(transcript)=1968nt_BP=577nt
AGCTTGTCCCCGCCTAGCAAGGAGTCGGCTAAGAACTGGATCCTAGCGAGGAGCCCGGCACAGACAGCGAATGACCGCAGCCAGACAGTC
GCTCTTGCTCTTCCTCGGCCCTGCGGCAGGATCCGCCGGTGCAGGGGCCTCTCCCCGGACTCCACGCGTGTCTGGAGGGCTCTCGGGTTA
GGGAAGGGGGCTTTGGAGACGCCCCGGGCGGCCGGGCGGTGGCGGGACGCGGGCCCTTTAAGAAGGAGCGAGGGGCGCGGCCAGGTAGGG
GCGGGTCCAGGGCGGATCAGCGCTGCGCCGGCGCCGGCCCGGGAGCCGGATTTGGAGCGCGAGGCGCCGGTGGGGGCGGAGGGGGCTGCG
CGGCGGAGGCTCCCGTGGCCTCGGACGCTCCTCCTAGCTAGCGGCCGCCGCCCGCCGCCGCCTGCGCCTCCAGCTCCTTCGCCCCGGCGG
GCCCGGCCGCCGCTTCCGGCAGCTCACCTGGGAAGCGCTCACCTGGGACGCGCTCACCTGGGACGCGCTACCTGCCTCCGGGCGCCTGGG
CTTCAGGATGAAGGACCGTCTGGAGCAGCTGAAGGCCTTCATCATCTCCGGATCCCTCTCAGTGGCAGCCGAGAAGAACCACACCAGTTG
CCTGGTGAGGAGCAGCCTGGGCACCAACATCCTCAGCGTCATGGCGGCCTTTGCTGGGACAGCCATTCTGCTCATGGATTTTGGTGTTAC
CAACCGGGATGTGGACAGGGGCTATCTGGCCGTGCTTACTATCTTCACTGTCCTGGAGTTCTTCACAGCGGTCATTGCCATGCACTTCGG
GTGCCAAGCCATCCATGCCCAGGCCAGTGCACCTGTGATCTTCCTGCCAAACGCCTTCAGCGCAGACTTCAACATCCCCAGCCCGGCAGC
CTCTGCGCCCCCTGCCTATGACAATGTGGCATATGCCCAAGGAGTCGTCTGAGTAGCAGATGTGGCACCTGCGGGTGGAGTCCAGCCTTT
TCCCTCTGGGCCCAGCCTCTCCCCACCCCCACCTTGTTCATCAGGGGCCAGCCCCATCCCAGCTGCCCTCCCTCACCACATCTACACATA
CTCCGGCATCTGAGTGAAGTGTCCCCAGGGACATCTCTCCCACACTTTCCCCAGTGCTTTCTTTCTAAAAGACACCGGGCTGACGTCAGG
GGTGTGTGTCCTTCAGCTCCCTGAGCCCTGTCACCCTTCCAGGACACCCACCTTGTGCATCTAAGCATTTCTCTGCTCATTGGGGAAATC
CTGGCCTCATTGGAGACTCAGGTTCGAGGCCTGCCCTGACCCTCGGGCCTCGGGAAGGTCAGAGAGCCCGGAATCCTCCAGAATGGAAGA
GTCTGACTCTGGCATTCCACAGAGGTGCCGATACCAGGCCAAGGCCTCACAGCAGGGTAGTGGCCTGGCCGCAGGTCTCCTGGCCCCAAG
ATCAGCTCTGTCCTTTGTCATCTGTTGCCACATCCATGGAACTCAGGTTTCCTATTTGGAAACTAGAGTGTTGAACCAGATAAGGTTCAT
CAGGCCCTTCCAGCTCCCCAGGCTCCCTGAAGTCCTGGGTCTAGGCCAGGCATTGTCCCCCTGCTTCCTGGAAACCCTCATTTTCCTTGT
CTGTAATATGAAGTCAGCATTGGCCCCGCCCCCCACCCCCTACCATCTCCCAATGGAGGGGAGGTTGCAGGGGAGAGCTGCCGCCAGCCC
ACTCCTGAGGCACCACCACAGTCAGCATCGACAGGGGCACAGCAGTGGCAGTTTGGGACCTCCCTGTGCCTCTCAGCACTCCCTTCCCCA
CCCCCATAGCCCAAGGACAAGGCTACCACAGAAGGTTACCACAGGACCTGGGCTTCGTCTCCAGGGGACAAGGAGACACTGTCAGCCTGG

>87814_87814_17_STX3-MS4A15_STX3_chr11_59523108_ENST00000535361_MS4A15_chr11_60538764_ENST00000405633_length(amino acids)=305AA_BP=192
MSPPSKESAKNWILARSPAQTANDRSQTVALALPRPCGRIRRCRGLSPDSTRVWRALGLGKGALETPRAAGRWRDAGPLRRSEGRGQVGA
GPGRISAAPAPAREPDLEREAPVGAEGAARRRLPWPRTLLLASGRRPPPPAPPAPSPRRARPPLPAAHLGSAHLGRAHLGRATCLRAPGL
QDEGPSGAAEGLHHLRIPLSGSREEPHQLPGEEQPGHQHPQRHGGLCWDSHSAHGFWCYQPGCGQGLSGRAYYLHCPGVLHSGHCHALRV

--------------------------------------------------------------
>87814_87814_18_STX3-MS4A15_STX3_chr11_59523108_ENST00000535361_MS4A15_chr11_60538764_ENST00000528170_length(transcript)=1036nt_BP=577nt
AGCTTGTCCCCGCCTAGCAAGGAGTCGGCTAAGAACTGGATCCTAGCGAGGAGCCCGGCACAGACAGCGAATGACCGCAGCCAGACAGTC
GCTCTTGCTCTTCCTCGGCCCTGCGGCAGGATCCGCCGGTGCAGGGGCCTCTCCCCGGACTCCACGCGTGTCTGGAGGGCTCTCGGGTTA
GGGAAGGGGGCTTTGGAGACGCCCCGGGCGGCCGGGCGGTGGCGGGACGCGGGCCCTTTAAGAAGGAGCGAGGGGCGCGGCCAGGTAGGG
GCGGGTCCAGGGCGGATCAGCGCTGCGCCGGCGCCGGCCCGGGAGCCGGATTTGGAGCGCGAGGCGCCGGTGGGGGCGGAGGGGGCTGCG
CGGCGGAGGCTCCCGTGGCCTCGGACGCTCCTCCTAGCTAGCGGCCGCCGCCCGCCGCCGCCTGCGCCTCCAGCTCCTTCGCCCCGGCGG
GCCCGGCCGCCGCTTCCGGCAGCTCACCTGGGAAGCGCTCACCTGGGACGCGCTCACCTGGGACGCGCTACCTGCCTCCGGGCGCCTGGG
CTTCAGGATGAAGGACCGTCTGGAGCAGCTGAAGGCCTTCATCATCTCCGGATCCCTCTCAGTGGCAGCCGAGAAGAACCACACCAGTTG
CCTGGTGAGGAGCAGCCTGGGCACCAACATCCTCAGCGTCATGGCGGCCTTTGCTGGGACAGCCATTCTGCTCATGGATTTTGGTGTTAC
CAACCGGGATGTGGACAGGGGCTATCTGGCCGTGCTTACTATCTTCACTGTCCTGGAGTTCTTCACAGCGGTCATTGCCATGCACTTCGG
GTGCCAAGCCATCCATGCCCAGGCCAGTGCACCTGTGATCTTCCTGCCAAACGCCTTCAGCGCAGACTTCAACATCCCCAGCCCGGCAGC
CTCTGCGCCCCCTGCCTATGACAATGTGGCATATGCCCAAGGAGTCGTCTGAGTAGCAGATGTGGCACCTGCGGGTGGAGTCCAGCCTTT

>87814_87814_18_STX3-MS4A15_STX3_chr11_59523108_ENST00000535361_MS4A15_chr11_60538764_ENST00000528170_length(amino acids)=305AA_BP=192
MSPPSKESAKNWILARSPAQTANDRSQTVALALPRPCGRIRRCRGLSPDSTRVWRALGLGKGALETPRAAGRWRDAGPLRRSEGRGQVGA
GPGRISAAPAPAREPDLEREAPVGAEGAARRRLPWPRTLLLASGRRPPPPAPPAPSPRRARPPLPAAHLGSAHLGRAHLGRATCLRAPGL
QDEGPSGAAEGLHHLRIPLSGSREEPHQLPGEEQPGHQHPQRHGGLCWDSHSAHGFWCYQPGCGQGLSGRAYYLHCPGVLHSGHCHALRV

--------------------------------------------------------------

Top

Fusion Gene PPI Analysis for STX3-MS4A15

Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in
ChiPPI page.

Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)

Hgene

Hgene's interactors

Tgene

Tgene's interactors

- Retained PPIs in in-frame fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Still interaction with

- Lost PPIs in in-frame fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Interaction lost with

- Retained PPIs, but lost function due to frame-shift fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Interaction lost with

Top

Related Drugs for STX3-MS4A15

Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)

Partner

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

Top

Related Diseases for STX3-MS4A15

Diseases associated with fusion partners.
(DisGeNet 4.0)

Partner

Gene

Disease ID

Disease name

# pubmeds

Source