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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:B9D1-ALDH16A1 (FusionGDB2 ID:8785)

Fusion Gene Summary for B9D1-ALDH16A1

check button Fusion gene summary
Fusion gene informationFusion gene name: B9D1-ALDH16A1
Fusion gene ID: 8785
HgeneTgene
Gene symbol

B9D1

ALDH16A1

Gene ID

27077

126133

Gene nameB9 domain containing 1aldehyde dehydrogenase 16 family member A1
SynonymsB9|EPPB9|JBTS27|MKS9|MKSR-1|MKSR1-
Cytomap

17p11.2

19q13.33

Type of geneprotein-codingprotein-coding
DescriptionB9 domain-containing protein 1B9 protein domain 1MKS1-related protein 1endothelial precursor protein B9aldehyde dehydrogenase family 16 member A1
Modification date2020031320200313
UniProtAcc

Q9UPM9

Q8IZ83

Ensembl transtripts involved in fusion geneENST00000261499, ENST00000268841, 
ENST00000395615, ENST00000395616, 
ENST00000461069, ENST00000477478, 
ENST00000575403, ENST00000468679, 
ENST00000598015, ENST00000433981, 
ENST00000455361, ENST00000540132, 
ENST00000293350, 
Fusion gene scores* DoF score5 X 5 X 5=1259 X 10 X 7=630
# samples 513
** MAII scorelog2(5/125*10)=-1.32192809488736
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(13/630*10)=-2.27684020535882
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: B9D1 [Title/Abstract] AND ALDH16A1 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointB9D1(19263633)-ALDH16A1(49961743), # samples:2
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check buttonFusion gene breakpoints across B9D1 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across ALDH16A1 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4BLCATCGA-E7-A7DV-01AB9D1chr17

19263633

-ALDH16A1chr19

49961743

+


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Fusion Gene ORF analysis for B9D1-ALDH16A1

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-3UTRENST00000261499ENST00000598015B9D1chr17

19263633

-ALDH16A1chr19

49961743

+
5CDS-3UTRENST00000268841ENST00000598015B9D1chr17

19263633

-ALDH16A1chr19

49961743

+
5CDS-3UTRENST00000395615ENST00000598015B9D1chr17

19263633

-ALDH16A1chr19

49961743

+
5CDS-3UTRENST00000395616ENST00000598015B9D1chr17

19263633

-ALDH16A1chr19

49961743

+
5CDS-3UTRENST00000461069ENST00000598015B9D1chr17

19263633

-ALDH16A1chr19

49961743

+
5CDS-3UTRENST00000477478ENST00000598015B9D1chr17

19263633

-ALDH16A1chr19

49961743

+
5CDS-3UTRENST00000575403ENST00000598015B9D1chr17

19263633

-ALDH16A1chr19

49961743

+
5CDS-intronENST00000261499ENST00000433981B9D1chr17

19263633

-ALDH16A1chr19

49961743

+
5CDS-intronENST00000261499ENST00000455361B9D1chr17

19263633

-ALDH16A1chr19

49961743

+
5CDS-intronENST00000261499ENST00000540132B9D1chr17

19263633

-ALDH16A1chr19

49961743

+
5CDS-intronENST00000268841ENST00000433981B9D1chr17

19263633

-ALDH16A1chr19

49961743

+
5CDS-intronENST00000268841ENST00000455361B9D1chr17

19263633

-ALDH16A1chr19

49961743

+
5CDS-intronENST00000268841ENST00000540132B9D1chr17

19263633

-ALDH16A1chr19

49961743

+
5CDS-intronENST00000395615ENST00000433981B9D1chr17

19263633

-ALDH16A1chr19

49961743

+
5CDS-intronENST00000395615ENST00000455361B9D1chr17

19263633

-ALDH16A1chr19

49961743

+
5CDS-intronENST00000395615ENST00000540132B9D1chr17

19263633

-ALDH16A1chr19

49961743

+
5CDS-intronENST00000395616ENST00000433981B9D1chr17

19263633

-ALDH16A1chr19

49961743

+
5CDS-intronENST00000395616ENST00000455361B9D1chr17

19263633

-ALDH16A1chr19

49961743

+
5CDS-intronENST00000395616ENST00000540132B9D1chr17

19263633

-ALDH16A1chr19

49961743

+
5CDS-intronENST00000461069ENST00000433981B9D1chr17

19263633

-ALDH16A1chr19

49961743

+
5CDS-intronENST00000461069ENST00000455361B9D1chr17

19263633

-ALDH16A1chr19

49961743

+
5CDS-intronENST00000461069ENST00000540132B9D1chr17

19263633

-ALDH16A1chr19

49961743

+
5CDS-intronENST00000477478ENST00000433981B9D1chr17

19263633

-ALDH16A1chr19

49961743

+
5CDS-intronENST00000477478ENST00000455361B9D1chr17

19263633

-ALDH16A1chr19

49961743

+
5CDS-intronENST00000477478ENST00000540132B9D1chr17

19263633

-ALDH16A1chr19

49961743

+
5CDS-intronENST00000575403ENST00000433981B9D1chr17

19263633

-ALDH16A1chr19

49961743

+
5CDS-intronENST00000575403ENST00000455361B9D1chr17

19263633

-ALDH16A1chr19

49961743

+
5CDS-intronENST00000575403ENST00000540132B9D1chr17

19263633

-ALDH16A1chr19

49961743

+
Frame-shiftENST00000477478ENST00000293350B9D1chr17

19263633

-ALDH16A1chr19

49961743

+
Frame-shiftENST00000575403ENST00000293350B9D1chr17

19263633

-ALDH16A1chr19

49961743

+
In-frameENST00000261499ENST00000293350B9D1chr17

19263633

-ALDH16A1chr19

49961743

+
In-frameENST00000268841ENST00000293350B9D1chr17

19263633

-ALDH16A1chr19

49961743

+
In-frameENST00000395615ENST00000293350B9D1chr17

19263633

-ALDH16A1chr19

49961743

+
In-frameENST00000395616ENST00000293350B9D1chr17

19263633

-ALDH16A1chr19

49961743

+
In-frameENST00000461069ENST00000293350B9D1chr17

19263633

-ALDH16A1chr19

49961743

+
intron-3CDSENST00000468679ENST00000293350B9D1chr17

19263633

-ALDH16A1chr19

49961743

+
intron-3UTRENST00000468679ENST00000598015B9D1chr17

19263633

-ALDH16A1chr19

49961743

+
intron-intronENST00000468679ENST00000433981B9D1chr17

19263633

-ALDH16A1chr19

49961743

+
intron-intronENST00000468679ENST00000455361B9D1chr17

19263633

-ALDH16A1chr19

49961743

+
intron-intronENST00000468679ENST00000540132B9D1chr17

19263633

-ALDH16A1chr19

49961743

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000461069B9D1chr1719263633-ENST00000293350ALDH16A1chr1949961743+3077177452495816
ENST00000395615B9D1chr1719263633-ENST00000293350ALDH16A1chr1949961743+303913972457816
ENST00000261499B9D1chr1719263633-ENST00000293350ALDH16A1chr1949961743+31762761442594816
ENST00000395616B9D1chr1719263633-ENST00000293350ALDH16A1chr1949961743+31962961642614816
ENST00000268841B9D1chr1719263633-ENST00000293350ALDH16A1chr1949961743+31322321002550816

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000461069ENST00000293350B9D1chr1719263633-ALDH16A1chr1949961743+0.0152198370.9847802
ENST00000395615ENST00000293350B9D1chr1719263633-ALDH16A1chr1949961743+0.0155241630.9844758
ENST00000261499ENST00000293350B9D1chr1719263633-ALDH16A1chr1949961743+0.0143861220.9856139
ENST00000395616ENST00000293350B9D1chr1719263633-ALDH16A1chr1949961743+0.014395990.98560405
ENST00000268841ENST00000293350B9D1chr1719263633-ALDH16A1chr1949961743+0.0142287530.9857713

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Fusion Genomic Features for B9D1-ALDH16A1


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
B9D1chr1719263632-ALDH16A1chr1949961742+9.45E-060.9999906
B9D1chr1719263632-ALDH16A1chr1949961742+9.45E-060.9999906

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for B9D1-ALDH16A1


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr17:19263633/chr19:49961743)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
B9D1

Q9UPM9

ALDH16A1

Q8IZ83

FUNCTION: Component of the tectonic-like complex, a complex localized at the transition zone of primary cilia and acting as a barrier that prevents diffusion of transmembrane proteins between the cilia and plasma membranes. Required for ciliogenesis and sonic hedgehog/SHH signaling (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneB9D1chr17:19263633chr19:49961743ENST00000261499-279_12744205.0DomainC2 B9-type
HgeneB9D1chr17:19263633chr19:49961743ENST00000268841-269_12744154.0DomainC2 B9-type


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Fusion Gene Sequence for B9D1-ALDH16A1


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>8785_8785_1_B9D1-ALDH16A1_B9D1_chr17_19263633_ENST00000261499_ALDH16A1_chr19_49961743_ENST00000293350_length(transcript)=3176nt_BP=276nt
CGCGCACTCGCGTGGCCTTCGCGAAGGTGTCGCTGCCAAGAAACGTGTCCTGCGCGCTACGCCGTCTGTTTCTAGGGCAACGCCGGCGTC
TCTTAGCAACCGCGCGCGGCCTAGGTGGGTCCCCCCGGCACCCCCAGACCTGCCATGGCGACCGCGAGTCCTAGCGTCTTTCTACTCATG
GTCAACGGGCAGGTGGAGAGCGCCCAGTTTCCAGAGTATGATGACCTCTACTGCAAGTACTGCTTTGTGTACGGCCAGGACTGGGCCCCC
ACAGCGGCCTGGCTGGACACCCAGGACCGGTGCTTGGGCCACTATGTGAATGGGAAGTGGTTAAAGCCTGAACACAGAAATTCAGTGCCT
TGCCAGGATCCCATCACAGGAGAGAACTTGGCCAGTTGCCTGCAGGCACAGGCCGAGGATGTGGCTGCAGCCGTGGAGGCAGCCAGGATG
GCATTTAAGGGCTGGAGTGCGCACCCCGGCGTCGTCCGGGCCCAGCACCTGACCAGGCTGGCCGAGGTGATCCAGAAGCACCAGCGGCTG
CTGTGGACCCTGGAATCCCTGGTGACTGGGCGGGCTGTTCGAGAGGTTCGAGACGGGGACGTCCAGCTGGCCCAGCAGCTGCTCCACTAC
CATGCAATCCAGGCATCCACCCAGGAGGAGGCACTGGCAGGCTGGGAGCCCATGGGAGTAATTGGCCTCATCCTGCCACCCACATTCTCC
TTCCTTGAGATGATGTGGAGGATTTGCCCTGCCCTGGCTGTGGGCTGCACCGTGGTGGCCCTCGTGCCCCCGGCCTCCCCGGCGCCCCTC
CTCCTGGCCCAGCTGGCGGGGGAGCTGGGCCCCTTCCCGGGAATCCTGAATGTCCTCAGTGGCCCTGCGTCCCTGGTGCCCATCCTGGCC
TCCCAGCCTGGAATCCGGAAGGTGGCCTTCTGCGGAGCCCCGGAGGAAGGGCGTGCCCTTCGACGGAGCCTGGCGGGAGAGTGTGCGGAG
CTGGGCCTGGCGCTGGGGACGGAGTCGCTGCTGCTGCTGACGGACACGGCGGACGTAGACTCGGCCGTGGAGGGTGTCGTGGACGCCGCC
TGGTCCGACCGCGGCCCGGGTGGCCTCAGGCTCCTCATCCAGGAGTCTGTGTGGGATGAAGCCATGAGACGGCTGCAGGAGCGGATGGGG
CGGCTTCGGAGTGGCCGAGGGCTGGATGGGGCCGTGGACATGGGGGCCCGGGGGGCTGCCGCATGTGACCTGGTCCAGCGCTTTGTGCGT
GAGGCCCAGAGCCAGGGTGCACAGGTGTTCCAGGCTGGTGATGTGCCTTCGGAACGCCCATTCTATCCCCCAACCTTGGTCTCCAACCTG
CCCCCAGCCTCCCCATGTGCCCAGGTGGAGGTGCCGTGGCCTGTGGTCGTGGCCTCCCCCTTCCGCACAGCCAAGGAGGCACTGTTGGTG
GCCAACGGGACGCCCCGCGGGGGCAGCGCCAGTGTGTGGAGCGAGAGGCTGGGGCAGGCGCTGGAGCTGGGCTATGGGCTCCAGGTGGGC
ACTGTCTGGATCAACGCCCACGGCCTCAGAGACCCTTCGGTGCCCACAGGCGGCTGCAAGGAGAGTGGGTGTTCCTGGCACGGGGGCCCA
GACGGGCTGTATGAGTATCTGCGGCCCTCAGGGACCCCTGCCCGGCTGTCCTGCCTCTCCAAGAACCTGAACTATGACACCTTTGGCCTC
GCTGTTCCCTCAACCCTGCCGGCTGGGCCTGAAATAGGGCCCAGCCCAGCACCCCCCTATGGGCTCTTCGTTGGGGGCCGTTTCCAGGCT
CCTGGGGCCCGAAGCTCCAGGCCCATCCGGGATTCGTCTGGCAACCTCCATGGCTACGTGGCTGAGGGTGGAGCCAAGGACATCCGAGGT
GCTGTGGAGGCCGCTCACCAGGCTTTCCCTGGCTGGGCGGGCCAGTCCCCAGGAGCCCGGGCAGCCCTGCTGTGGGCCCTGGCGGCTGCA
CTGGAGCGCCGGAAGTCTACCCTGGCCTCGAGGCTGGAGAGGCAGGGAGCGGAGCTCAAGGCTGCGGAGGCGGAGGTGGAGCTGAGCGCA
AGACGACTTCGGGCGTGGGGGGCCCGGGTGCAGGCCCAAGGCCACACCCTGCAGGTAGCCGGGCTGAGAGGCCCTGTGCTGCGCCTGCGG
GAGCCGCTGGGTGTGCTGGCTGTGGTGTGTCCGGACGAGTGGCCCCTGCTTGCCTTCGTGTCCCTGCTGGCTCCCGCCCTGGCCTACGGC
AACACTGTGGTCATGGTGCCCAGTGCGGCCTGTCCTCTGCTGGCCCTGGAGGTCTGCCAGGACATGGCCACCGTGTTCCCAGCAGGCCTG
GCCAACGTGGTGACAGGAGACCGGGACCATCTGACCCGCTGCCTGGCCTTGCACCAAGACGTCCAGGCCATGTGGTATTTCGGATCAGCC
CAGGGTTCCCAGTTTGTCGAGTGGGCCTCGGCAGGAAACCTCAAACCGGTGTGGGCGAGCAGGGGCTGCCCGCGGGCCTGGGACCAGGAG
GCCGAGGGGGCAGGCCCAGAGCTGGGGCTGCGAGTGGCGCGGACCAAGGCCCTGTGGCTGCCTATGGGGGACTGATGCCTGAGCGCCACC
TACTGCATTTTGGACACCTCACACCAAGGGGAGATGCACCCCACAGACACCTGGGACTTTCCCCTTCTGGTTCCTGTGTCTCCCAATAAA
CTCTCTGACCAACCCTAGCTGTGCTTCTGCGAGAAGAAAGGGTGTAGCAACTTCTGGCAGATATGAGGCTTTTTTCTTTTTTTTTTTTTT
TTTTGAGACAACGTCTGGCTCTGTCACCCAGGCTGGAGCGCAGTGGCACAATCTCGGCCCACTGCAGCCTCGACCTCTGGGGCTCAAGGG
ATCCTCATGCCTCAGCCTCATATGTAGCTGGGGCCACAGACATGCACCACCACACCTGGCTCGAGGCCATTTTAGTTCTGAGGTTGAGCA
GCTCAGGAGCCGGCTCCAGCACGGTGCTGTGTTTGTGAAACAGAGAAAGGGGACCCCCGAGGACCCCAGACAGGGCCTTAGGACTCTCAT
ATCTTCTTGTCTTCTCCATCTGGTGGCTCTTGCTCTCTGGTTTTCTCTACCTTTTCATGGCCCCAGAATCCATATGCAGTAAAGGAACTC

>8785_8785_1_B9D1-ALDH16A1_B9D1_chr17_19263633_ENST00000261499_ALDH16A1_chr19_49961743_ENST00000293350_length(amino acids)=816AA_BP=44
MATASPSVFLLMVNGQVESAQFPEYDDLYCKYCFVYGQDWAPTAAWLDTQDRCLGHYVNGKWLKPEHRNSVPCQDPITGENLASCLQAQA
EDVAAAVEAARMAFKGWSAHPGVVRAQHLTRLAEVIQKHQRLLWTLESLVTGRAVREVRDGDVQLAQQLLHYHAIQASTQEEALAGWEPM
GVIGLILPPTFSFLEMMWRICPALAVGCTVVALVPPASPAPLLLAQLAGELGPFPGILNVLSGPASLVPILASQPGIRKVAFCGAPEEGR
ALRRSLAGECAELGLALGTESLLLLTDTADVDSAVEGVVDAAWSDRGPGGLRLLIQESVWDEAMRRLQERMGRLRSGRGLDGAVDMGARG
AAACDLVQRFVREAQSQGAQVFQAGDVPSERPFYPPTLVSNLPPASPCAQVEVPWPVVVASPFRTAKEALLVANGTPRGGSASVWSERLG
QALELGYGLQVGTVWINAHGLRDPSVPTGGCKESGCSWHGGPDGLYEYLRPSGTPARLSCLSKNLNYDTFGLAVPSTLPAGPEIGPSPAP
PYGLFVGGRFQAPGARSSRPIRDSSGNLHGYVAEGGAKDIRGAVEAAHQAFPGWAGQSPGARAALLWALAAALERRKSTLASRLERQGAE
LKAAEAEVELSARRLRAWGARVQAQGHTLQVAGLRGPVLRLREPLGVLAVVCPDEWPLLAFVSLLAPALAYGNTVVMVPSAACPLLALEV
CQDMATVFPAGLANVVTGDRDHLTRCLALHQDVQAMWYFGSAQGSQFVEWASAGNLKPVWASRGCPRAWDQEAEGAGPELGLRVARTKAL

--------------------------------------------------------------
>8785_8785_2_B9D1-ALDH16A1_B9D1_chr17_19263633_ENST00000268841_ALDH16A1_chr19_49961743_ENST00000293350_length(transcript)=3132nt_BP=232nt
GTGTCCTGCGCGCTACGCCGTCTGTTTCTAGGGCAACGCCGGCGTCTCTTAGCAACCGCGCGCGGCCTAGGTGGGTCCCCCCGGCACCCC
CAGACCTGCCATGGCGACCGCGAGTCCTAGCGTCTTTCTACTCATGGTCAACGGGCAGGTGGAGAGCGCCCAGTTTCCAGAGTATGATGA
CCTCTACTGCAAGTACTGCTTTGTGTACGGCCAGGACTGGGCCCCCACAGCGGCCTGGCTGGACACCCAGGACCGGTGCTTGGGCCACTA
TGTGAATGGGAAGTGGTTAAAGCCTGAACACAGAAATTCAGTGCCTTGCCAGGATCCCATCACAGGAGAGAACTTGGCCAGTTGCCTGCA
GGCACAGGCCGAGGATGTGGCTGCAGCCGTGGAGGCAGCCAGGATGGCATTTAAGGGCTGGAGTGCGCACCCCGGCGTCGTCCGGGCCCA
GCACCTGACCAGGCTGGCCGAGGTGATCCAGAAGCACCAGCGGCTGCTGTGGACCCTGGAATCCCTGGTGACTGGGCGGGCTGTTCGAGA
GGTTCGAGACGGGGACGTCCAGCTGGCCCAGCAGCTGCTCCACTACCATGCAATCCAGGCATCCACCCAGGAGGAGGCACTGGCAGGCTG
GGAGCCCATGGGAGTAATTGGCCTCATCCTGCCACCCACATTCTCCTTCCTTGAGATGATGTGGAGGATTTGCCCTGCCCTGGCTGTGGG
CTGCACCGTGGTGGCCCTCGTGCCCCCGGCCTCCCCGGCGCCCCTCCTCCTGGCCCAGCTGGCGGGGGAGCTGGGCCCCTTCCCGGGAAT
CCTGAATGTCCTCAGTGGCCCTGCGTCCCTGGTGCCCATCCTGGCCTCCCAGCCTGGAATCCGGAAGGTGGCCTTCTGCGGAGCCCCGGA
GGAAGGGCGTGCCCTTCGACGGAGCCTGGCGGGAGAGTGTGCGGAGCTGGGCCTGGCGCTGGGGACGGAGTCGCTGCTGCTGCTGACGGA
CACGGCGGACGTAGACTCGGCCGTGGAGGGTGTCGTGGACGCCGCCTGGTCCGACCGCGGCCCGGGTGGCCTCAGGCTCCTCATCCAGGA
GTCTGTGTGGGATGAAGCCATGAGACGGCTGCAGGAGCGGATGGGGCGGCTTCGGAGTGGCCGAGGGCTGGATGGGGCCGTGGACATGGG
GGCCCGGGGGGCTGCCGCATGTGACCTGGTCCAGCGCTTTGTGCGTGAGGCCCAGAGCCAGGGTGCACAGGTGTTCCAGGCTGGTGATGT
GCCTTCGGAACGCCCATTCTATCCCCCAACCTTGGTCTCCAACCTGCCCCCAGCCTCCCCATGTGCCCAGGTGGAGGTGCCGTGGCCTGT
GGTCGTGGCCTCCCCCTTCCGCACAGCCAAGGAGGCACTGTTGGTGGCCAACGGGACGCCCCGCGGGGGCAGCGCCAGTGTGTGGAGCGA
GAGGCTGGGGCAGGCGCTGGAGCTGGGCTATGGGCTCCAGGTGGGCACTGTCTGGATCAACGCCCACGGCCTCAGAGACCCTTCGGTGCC
CACAGGCGGCTGCAAGGAGAGTGGGTGTTCCTGGCACGGGGGCCCAGACGGGCTGTATGAGTATCTGCGGCCCTCAGGGACCCCTGCCCG
GCTGTCCTGCCTCTCCAAGAACCTGAACTATGACACCTTTGGCCTCGCTGTTCCCTCAACCCTGCCGGCTGGGCCTGAAATAGGGCCCAG
CCCAGCACCCCCCTATGGGCTCTTCGTTGGGGGCCGTTTCCAGGCTCCTGGGGCCCGAAGCTCCAGGCCCATCCGGGATTCGTCTGGCAA
CCTCCATGGCTACGTGGCTGAGGGTGGAGCCAAGGACATCCGAGGTGCTGTGGAGGCCGCTCACCAGGCTTTCCCTGGCTGGGCGGGCCA
GTCCCCAGGAGCCCGGGCAGCCCTGCTGTGGGCCCTGGCGGCTGCACTGGAGCGCCGGAAGTCTACCCTGGCCTCGAGGCTGGAGAGGCA
GGGAGCGGAGCTCAAGGCTGCGGAGGCGGAGGTGGAGCTGAGCGCAAGACGACTTCGGGCGTGGGGGGCCCGGGTGCAGGCCCAAGGCCA
CACCCTGCAGGTAGCCGGGCTGAGAGGCCCTGTGCTGCGCCTGCGGGAGCCGCTGGGTGTGCTGGCTGTGGTGTGTCCGGACGAGTGGCC
CCTGCTTGCCTTCGTGTCCCTGCTGGCTCCCGCCCTGGCCTACGGCAACACTGTGGTCATGGTGCCCAGTGCGGCCTGTCCTCTGCTGGC
CCTGGAGGTCTGCCAGGACATGGCCACCGTGTTCCCAGCAGGCCTGGCCAACGTGGTGACAGGAGACCGGGACCATCTGACCCGCTGCCT
GGCCTTGCACCAAGACGTCCAGGCCATGTGGTATTTCGGATCAGCCCAGGGTTCCCAGTTTGTCGAGTGGGCCTCGGCAGGAAACCTCAA
ACCGGTGTGGGCGAGCAGGGGCTGCCCGCGGGCCTGGGACCAGGAGGCCGAGGGGGCAGGCCCAGAGCTGGGGCTGCGAGTGGCGCGGAC
CAAGGCCCTGTGGCTGCCTATGGGGGACTGATGCCTGAGCGCCACCTACTGCATTTTGGACACCTCACACCAAGGGGAGATGCACCCCAC
AGACACCTGGGACTTTCCCCTTCTGGTTCCTGTGTCTCCCAATAAACTCTCTGACCAACCCTAGCTGTGCTTCTGCGAGAAGAAAGGGTG
TAGCAACTTCTGGCAGATATGAGGCTTTTTTCTTTTTTTTTTTTTTTTTTGAGACAACGTCTGGCTCTGTCACCCAGGCTGGAGCGCAGT
GGCACAATCTCGGCCCACTGCAGCCTCGACCTCTGGGGCTCAAGGGATCCTCATGCCTCAGCCTCATATGTAGCTGGGGCCACAGACATG
CACCACCACACCTGGCTCGAGGCCATTTTAGTTCTGAGGTTGAGCAGCTCAGGAGCCGGCTCCAGCACGGTGCTGTGTTTGTGAAACAGA
GAAAGGGGACCCCCGAGGACCCCAGACAGGGCCTTAGGACTCTCATATCTTCTTGTCTTCTCCATCTGGTGGCTCTTGCTCTCTGGTTTT

>8785_8785_2_B9D1-ALDH16A1_B9D1_chr17_19263633_ENST00000268841_ALDH16A1_chr19_49961743_ENST00000293350_length(amino acids)=816AA_BP=44
MATASPSVFLLMVNGQVESAQFPEYDDLYCKYCFVYGQDWAPTAAWLDTQDRCLGHYVNGKWLKPEHRNSVPCQDPITGENLASCLQAQA
EDVAAAVEAARMAFKGWSAHPGVVRAQHLTRLAEVIQKHQRLLWTLESLVTGRAVREVRDGDVQLAQQLLHYHAIQASTQEEALAGWEPM
GVIGLILPPTFSFLEMMWRICPALAVGCTVVALVPPASPAPLLLAQLAGELGPFPGILNVLSGPASLVPILASQPGIRKVAFCGAPEEGR
ALRRSLAGECAELGLALGTESLLLLTDTADVDSAVEGVVDAAWSDRGPGGLRLLIQESVWDEAMRRLQERMGRLRSGRGLDGAVDMGARG
AAACDLVQRFVREAQSQGAQVFQAGDVPSERPFYPPTLVSNLPPASPCAQVEVPWPVVVASPFRTAKEALLVANGTPRGGSASVWSERLG
QALELGYGLQVGTVWINAHGLRDPSVPTGGCKESGCSWHGGPDGLYEYLRPSGTPARLSCLSKNLNYDTFGLAVPSTLPAGPEIGPSPAP
PYGLFVGGRFQAPGARSSRPIRDSSGNLHGYVAEGGAKDIRGAVEAAHQAFPGWAGQSPGARAALLWALAAALERRKSTLASRLERQGAE
LKAAEAEVELSARRLRAWGARVQAQGHTLQVAGLRGPVLRLREPLGVLAVVCPDEWPLLAFVSLLAPALAYGNTVVMVPSAACPLLALEV
CQDMATVFPAGLANVVTGDRDHLTRCLALHQDVQAMWYFGSAQGSQFVEWASAGNLKPVWASRGCPRAWDQEAEGAGPELGLRVARTKAL

--------------------------------------------------------------
>8785_8785_3_B9D1-ALDH16A1_B9D1_chr17_19263633_ENST00000395615_ALDH16A1_chr19_49961743_ENST00000293350_length(transcript)=3039nt_BP=139nt
ACCTGCCATGGCGACCGCGAGTCCTAGCGTCTTTCTACTCATGGTCAACGGGCAGGTGGAGAGCGCCCAGTTTCCAGAGTATGATGACCT
CTACTGCAAGTACTGCTTTGTGTACGGCCAGGACTGGGCCCCCACAGCGGCCTGGCTGGACACCCAGGACCGGTGCTTGGGCCACTATGT
GAATGGGAAGTGGTTAAAGCCTGAACACAGAAATTCAGTGCCTTGCCAGGATCCCATCACAGGAGAGAACTTGGCCAGTTGCCTGCAGGC
ACAGGCCGAGGATGTGGCTGCAGCCGTGGAGGCAGCCAGGATGGCATTTAAGGGCTGGAGTGCGCACCCCGGCGTCGTCCGGGCCCAGCA
CCTGACCAGGCTGGCCGAGGTGATCCAGAAGCACCAGCGGCTGCTGTGGACCCTGGAATCCCTGGTGACTGGGCGGGCTGTTCGAGAGGT
TCGAGACGGGGACGTCCAGCTGGCCCAGCAGCTGCTCCACTACCATGCAATCCAGGCATCCACCCAGGAGGAGGCACTGGCAGGCTGGGA
GCCCATGGGAGTAATTGGCCTCATCCTGCCACCCACATTCTCCTTCCTTGAGATGATGTGGAGGATTTGCCCTGCCCTGGCTGTGGGCTG
CACCGTGGTGGCCCTCGTGCCCCCGGCCTCCCCGGCGCCCCTCCTCCTGGCCCAGCTGGCGGGGGAGCTGGGCCCCTTCCCGGGAATCCT
GAATGTCCTCAGTGGCCCTGCGTCCCTGGTGCCCATCCTGGCCTCCCAGCCTGGAATCCGGAAGGTGGCCTTCTGCGGAGCCCCGGAGGA
AGGGCGTGCCCTTCGACGGAGCCTGGCGGGAGAGTGTGCGGAGCTGGGCCTGGCGCTGGGGACGGAGTCGCTGCTGCTGCTGACGGACAC
GGCGGACGTAGACTCGGCCGTGGAGGGTGTCGTGGACGCCGCCTGGTCCGACCGCGGCCCGGGTGGCCTCAGGCTCCTCATCCAGGAGTC
TGTGTGGGATGAAGCCATGAGACGGCTGCAGGAGCGGATGGGGCGGCTTCGGAGTGGCCGAGGGCTGGATGGGGCCGTGGACATGGGGGC
CCGGGGGGCTGCCGCATGTGACCTGGTCCAGCGCTTTGTGCGTGAGGCCCAGAGCCAGGGTGCACAGGTGTTCCAGGCTGGTGATGTGCC
TTCGGAACGCCCATTCTATCCCCCAACCTTGGTCTCCAACCTGCCCCCAGCCTCCCCATGTGCCCAGGTGGAGGTGCCGTGGCCTGTGGT
CGTGGCCTCCCCCTTCCGCACAGCCAAGGAGGCACTGTTGGTGGCCAACGGGACGCCCCGCGGGGGCAGCGCCAGTGTGTGGAGCGAGAG
GCTGGGGCAGGCGCTGGAGCTGGGCTATGGGCTCCAGGTGGGCACTGTCTGGATCAACGCCCACGGCCTCAGAGACCCTTCGGTGCCCAC
AGGCGGCTGCAAGGAGAGTGGGTGTTCCTGGCACGGGGGCCCAGACGGGCTGTATGAGTATCTGCGGCCCTCAGGGACCCCTGCCCGGCT
GTCCTGCCTCTCCAAGAACCTGAACTATGACACCTTTGGCCTCGCTGTTCCCTCAACCCTGCCGGCTGGGCCTGAAATAGGGCCCAGCCC
AGCACCCCCCTATGGGCTCTTCGTTGGGGGCCGTTTCCAGGCTCCTGGGGCCCGAAGCTCCAGGCCCATCCGGGATTCGTCTGGCAACCT
CCATGGCTACGTGGCTGAGGGTGGAGCCAAGGACATCCGAGGTGCTGTGGAGGCCGCTCACCAGGCTTTCCCTGGCTGGGCGGGCCAGTC
CCCAGGAGCCCGGGCAGCCCTGCTGTGGGCCCTGGCGGCTGCACTGGAGCGCCGGAAGTCTACCCTGGCCTCGAGGCTGGAGAGGCAGGG
AGCGGAGCTCAAGGCTGCGGAGGCGGAGGTGGAGCTGAGCGCAAGACGACTTCGGGCGTGGGGGGCCCGGGTGCAGGCCCAAGGCCACAC
CCTGCAGGTAGCCGGGCTGAGAGGCCCTGTGCTGCGCCTGCGGGAGCCGCTGGGTGTGCTGGCTGTGGTGTGTCCGGACGAGTGGCCCCT
GCTTGCCTTCGTGTCCCTGCTGGCTCCCGCCCTGGCCTACGGCAACACTGTGGTCATGGTGCCCAGTGCGGCCTGTCCTCTGCTGGCCCT
GGAGGTCTGCCAGGACATGGCCACCGTGTTCCCAGCAGGCCTGGCCAACGTGGTGACAGGAGACCGGGACCATCTGACCCGCTGCCTGGC
CTTGCACCAAGACGTCCAGGCCATGTGGTATTTCGGATCAGCCCAGGGTTCCCAGTTTGTCGAGTGGGCCTCGGCAGGAAACCTCAAACC
GGTGTGGGCGAGCAGGGGCTGCCCGCGGGCCTGGGACCAGGAGGCCGAGGGGGCAGGCCCAGAGCTGGGGCTGCGAGTGGCGCGGACCAA
GGCCCTGTGGCTGCCTATGGGGGACTGATGCCTGAGCGCCACCTACTGCATTTTGGACACCTCACACCAAGGGGAGATGCACCCCACAGA
CACCTGGGACTTTCCCCTTCTGGTTCCTGTGTCTCCCAATAAACTCTCTGACCAACCCTAGCTGTGCTTCTGCGAGAAGAAAGGGTGTAG
CAACTTCTGGCAGATATGAGGCTTTTTTCTTTTTTTTTTTTTTTTTTGAGACAACGTCTGGCTCTGTCACCCAGGCTGGAGCGCAGTGGC
ACAATCTCGGCCCACTGCAGCCTCGACCTCTGGGGCTCAAGGGATCCTCATGCCTCAGCCTCATATGTAGCTGGGGCCACAGACATGCAC
CACCACACCTGGCTCGAGGCCATTTTAGTTCTGAGGTTGAGCAGCTCAGGAGCCGGCTCCAGCACGGTGCTGTGTTTGTGAAACAGAGAA
AGGGGACCCCCGAGGACCCCAGACAGGGCCTTAGGACTCTCATATCTTCTTGTCTTCTCCATCTGGTGGCTCTTGCTCTCTGGTTTTCTC

>8785_8785_3_B9D1-ALDH16A1_B9D1_chr17_19263633_ENST00000395615_ALDH16A1_chr19_49961743_ENST00000293350_length(amino acids)=816AA_BP=44
MATASPSVFLLMVNGQVESAQFPEYDDLYCKYCFVYGQDWAPTAAWLDTQDRCLGHYVNGKWLKPEHRNSVPCQDPITGENLASCLQAQA
EDVAAAVEAARMAFKGWSAHPGVVRAQHLTRLAEVIQKHQRLLWTLESLVTGRAVREVRDGDVQLAQQLLHYHAIQASTQEEALAGWEPM
GVIGLILPPTFSFLEMMWRICPALAVGCTVVALVPPASPAPLLLAQLAGELGPFPGILNVLSGPASLVPILASQPGIRKVAFCGAPEEGR
ALRRSLAGECAELGLALGTESLLLLTDTADVDSAVEGVVDAAWSDRGPGGLRLLIQESVWDEAMRRLQERMGRLRSGRGLDGAVDMGARG
AAACDLVQRFVREAQSQGAQVFQAGDVPSERPFYPPTLVSNLPPASPCAQVEVPWPVVVASPFRTAKEALLVANGTPRGGSASVWSERLG
QALELGYGLQVGTVWINAHGLRDPSVPTGGCKESGCSWHGGPDGLYEYLRPSGTPARLSCLSKNLNYDTFGLAVPSTLPAGPEIGPSPAP
PYGLFVGGRFQAPGARSSRPIRDSSGNLHGYVAEGGAKDIRGAVEAAHQAFPGWAGQSPGARAALLWALAAALERRKSTLASRLERQGAE
LKAAEAEVELSARRLRAWGARVQAQGHTLQVAGLRGPVLRLREPLGVLAVVCPDEWPLLAFVSLLAPALAYGNTVVMVPSAACPLLALEV
CQDMATVFPAGLANVVTGDRDHLTRCLALHQDVQAMWYFGSAQGSQFVEWASAGNLKPVWASRGCPRAWDQEAEGAGPELGLRVARTKAL

--------------------------------------------------------------
>8785_8785_4_B9D1-ALDH16A1_B9D1_chr17_19263633_ENST00000395616_ALDH16A1_chr19_49961743_ENST00000293350_length(transcript)=3196nt_BP=296nt
CTGCGCCTGCGCATGCCACACGCGCACTCGCGTGGCCTTCGCGAAGGTGTCGCTGCCAAGAAACGTGTCCTGCGCGCTACGCCGTCTGTT
TCTAGGGCAACGCCGGCGTCTCTTAGCAACCGCGCGCGGCCTAGGTGGGTCCCCCCGGCACCCCCAGACCTGCCATGGCGACCGCGAGTC
CTAGCGTCTTTCTACTCATGGTCAACGGGCAGGTGGAGAGCGCCCAGTTTCCAGAGTATGATGACCTCTACTGCAAGTACTGCTTTGTGT
ACGGCCAGGACTGGGCCCCCACAGCGGCCTGGCTGGACACCCAGGACCGGTGCTTGGGCCACTATGTGAATGGGAAGTGGTTAAAGCCTG
AACACAGAAATTCAGTGCCTTGCCAGGATCCCATCACAGGAGAGAACTTGGCCAGTTGCCTGCAGGCACAGGCCGAGGATGTGGCTGCAG
CCGTGGAGGCAGCCAGGATGGCATTTAAGGGCTGGAGTGCGCACCCCGGCGTCGTCCGGGCCCAGCACCTGACCAGGCTGGCCGAGGTGA
TCCAGAAGCACCAGCGGCTGCTGTGGACCCTGGAATCCCTGGTGACTGGGCGGGCTGTTCGAGAGGTTCGAGACGGGGACGTCCAGCTGG
CCCAGCAGCTGCTCCACTACCATGCAATCCAGGCATCCACCCAGGAGGAGGCACTGGCAGGCTGGGAGCCCATGGGAGTAATTGGCCTCA
TCCTGCCACCCACATTCTCCTTCCTTGAGATGATGTGGAGGATTTGCCCTGCCCTGGCTGTGGGCTGCACCGTGGTGGCCCTCGTGCCCC
CGGCCTCCCCGGCGCCCCTCCTCCTGGCCCAGCTGGCGGGGGAGCTGGGCCCCTTCCCGGGAATCCTGAATGTCCTCAGTGGCCCTGCGT
CCCTGGTGCCCATCCTGGCCTCCCAGCCTGGAATCCGGAAGGTGGCCTTCTGCGGAGCCCCGGAGGAAGGGCGTGCCCTTCGACGGAGCC
TGGCGGGAGAGTGTGCGGAGCTGGGCCTGGCGCTGGGGACGGAGTCGCTGCTGCTGCTGACGGACACGGCGGACGTAGACTCGGCCGTGG
AGGGTGTCGTGGACGCCGCCTGGTCCGACCGCGGCCCGGGTGGCCTCAGGCTCCTCATCCAGGAGTCTGTGTGGGATGAAGCCATGAGAC
GGCTGCAGGAGCGGATGGGGCGGCTTCGGAGTGGCCGAGGGCTGGATGGGGCCGTGGACATGGGGGCCCGGGGGGCTGCCGCATGTGACC
TGGTCCAGCGCTTTGTGCGTGAGGCCCAGAGCCAGGGTGCACAGGTGTTCCAGGCTGGTGATGTGCCTTCGGAACGCCCATTCTATCCCC
CAACCTTGGTCTCCAACCTGCCCCCAGCCTCCCCATGTGCCCAGGTGGAGGTGCCGTGGCCTGTGGTCGTGGCCTCCCCCTTCCGCACAG
CCAAGGAGGCACTGTTGGTGGCCAACGGGACGCCCCGCGGGGGCAGCGCCAGTGTGTGGAGCGAGAGGCTGGGGCAGGCGCTGGAGCTGG
GCTATGGGCTCCAGGTGGGCACTGTCTGGATCAACGCCCACGGCCTCAGAGACCCTTCGGTGCCCACAGGCGGCTGCAAGGAGAGTGGGT
GTTCCTGGCACGGGGGCCCAGACGGGCTGTATGAGTATCTGCGGCCCTCAGGGACCCCTGCCCGGCTGTCCTGCCTCTCCAAGAACCTGA
ACTATGACACCTTTGGCCTCGCTGTTCCCTCAACCCTGCCGGCTGGGCCTGAAATAGGGCCCAGCCCAGCACCCCCCTATGGGCTCTTCG
TTGGGGGCCGTTTCCAGGCTCCTGGGGCCCGAAGCTCCAGGCCCATCCGGGATTCGTCTGGCAACCTCCATGGCTACGTGGCTGAGGGTG
GAGCCAAGGACATCCGAGGTGCTGTGGAGGCCGCTCACCAGGCTTTCCCTGGCTGGGCGGGCCAGTCCCCAGGAGCCCGGGCAGCCCTGC
TGTGGGCCCTGGCGGCTGCACTGGAGCGCCGGAAGTCTACCCTGGCCTCGAGGCTGGAGAGGCAGGGAGCGGAGCTCAAGGCTGCGGAGG
CGGAGGTGGAGCTGAGCGCAAGACGACTTCGGGCGTGGGGGGCCCGGGTGCAGGCCCAAGGCCACACCCTGCAGGTAGCCGGGCTGAGAG
GCCCTGTGCTGCGCCTGCGGGAGCCGCTGGGTGTGCTGGCTGTGGTGTGTCCGGACGAGTGGCCCCTGCTTGCCTTCGTGTCCCTGCTGG
CTCCCGCCCTGGCCTACGGCAACACTGTGGTCATGGTGCCCAGTGCGGCCTGTCCTCTGCTGGCCCTGGAGGTCTGCCAGGACATGGCCA
CCGTGTTCCCAGCAGGCCTGGCCAACGTGGTGACAGGAGACCGGGACCATCTGACCCGCTGCCTGGCCTTGCACCAAGACGTCCAGGCCA
TGTGGTATTTCGGATCAGCCCAGGGTTCCCAGTTTGTCGAGTGGGCCTCGGCAGGAAACCTCAAACCGGTGTGGGCGAGCAGGGGCTGCC
CGCGGGCCTGGGACCAGGAGGCCGAGGGGGCAGGCCCAGAGCTGGGGCTGCGAGTGGCGCGGACCAAGGCCCTGTGGCTGCCTATGGGGG
ACTGATGCCTGAGCGCCACCTACTGCATTTTGGACACCTCACACCAAGGGGAGATGCACCCCACAGACACCTGGGACTTTCCCCTTCTGG
TTCCTGTGTCTCCCAATAAACTCTCTGACCAACCCTAGCTGTGCTTCTGCGAGAAGAAAGGGTGTAGCAACTTCTGGCAGATATGAGGCT
TTTTTCTTTTTTTTTTTTTTTTTTGAGACAACGTCTGGCTCTGTCACCCAGGCTGGAGCGCAGTGGCACAATCTCGGCCCACTGCAGCCT
CGACCTCTGGGGCTCAAGGGATCCTCATGCCTCAGCCTCATATGTAGCTGGGGCCACAGACATGCACCACCACACCTGGCTCGAGGCCAT
TTTAGTTCTGAGGTTGAGCAGCTCAGGAGCCGGCTCCAGCACGGTGCTGTGTTTGTGAAACAGAGAAAGGGGACCCCCGAGGACCCCAGA
CAGGGCCTTAGGACTCTCATATCTTCTTGTCTTCTCCATCTGGTGGCTCTTGCTCTCTGGTTTTCTCTACCTTTTCATGGCCCCAGAATC

>8785_8785_4_B9D1-ALDH16A1_B9D1_chr17_19263633_ENST00000395616_ALDH16A1_chr19_49961743_ENST00000293350_length(amino acids)=816AA_BP=44
MATASPSVFLLMVNGQVESAQFPEYDDLYCKYCFVYGQDWAPTAAWLDTQDRCLGHYVNGKWLKPEHRNSVPCQDPITGENLASCLQAQA
EDVAAAVEAARMAFKGWSAHPGVVRAQHLTRLAEVIQKHQRLLWTLESLVTGRAVREVRDGDVQLAQQLLHYHAIQASTQEEALAGWEPM
GVIGLILPPTFSFLEMMWRICPALAVGCTVVALVPPASPAPLLLAQLAGELGPFPGILNVLSGPASLVPILASQPGIRKVAFCGAPEEGR
ALRRSLAGECAELGLALGTESLLLLTDTADVDSAVEGVVDAAWSDRGPGGLRLLIQESVWDEAMRRLQERMGRLRSGRGLDGAVDMGARG
AAACDLVQRFVREAQSQGAQVFQAGDVPSERPFYPPTLVSNLPPASPCAQVEVPWPVVVASPFRTAKEALLVANGTPRGGSASVWSERLG
QALELGYGLQVGTVWINAHGLRDPSVPTGGCKESGCSWHGGPDGLYEYLRPSGTPARLSCLSKNLNYDTFGLAVPSTLPAGPEIGPSPAP
PYGLFVGGRFQAPGARSSRPIRDSSGNLHGYVAEGGAKDIRGAVEAAHQAFPGWAGQSPGARAALLWALAAALERRKSTLASRLERQGAE
LKAAEAEVELSARRLRAWGARVQAQGHTLQVAGLRGPVLRLREPLGVLAVVCPDEWPLLAFVSLLAPALAYGNTVVMVPSAACPLLALEV
CQDMATVFPAGLANVVTGDRDHLTRCLALHQDVQAMWYFGSAQGSQFVEWASAGNLKPVWASRGCPRAWDQEAEGAGPELGLRVARTKAL

--------------------------------------------------------------
>8785_8785_5_B9D1-ALDH16A1_B9D1_chr17_19263633_ENST00000461069_ALDH16A1_chr19_49961743_ENST00000293350_length(transcript)=3077nt_BP=177nt
CCGCGCGCGGCCTAGGTGGGTCCCCCCGGCACCCCCAGACCTGCCATGGCGACCGCGAGTCCTAGCGTCTTTCTACTCATGGTCAACGGG
CAGGTGGAGAGCGCCCAGTTTCCAGAGTATGATGACCTCTACTGCAAGTACTGCTTTGTGTACGGCCAGGACTGGGCCCCCACAGCGGCC
TGGCTGGACACCCAGGACCGGTGCTTGGGCCACTATGTGAATGGGAAGTGGTTAAAGCCTGAACACAGAAATTCAGTGCCTTGCCAGGAT
CCCATCACAGGAGAGAACTTGGCCAGTTGCCTGCAGGCACAGGCCGAGGATGTGGCTGCAGCCGTGGAGGCAGCCAGGATGGCATTTAAG
GGCTGGAGTGCGCACCCCGGCGTCGTCCGGGCCCAGCACCTGACCAGGCTGGCCGAGGTGATCCAGAAGCACCAGCGGCTGCTGTGGACC
CTGGAATCCCTGGTGACTGGGCGGGCTGTTCGAGAGGTTCGAGACGGGGACGTCCAGCTGGCCCAGCAGCTGCTCCACTACCATGCAATC
CAGGCATCCACCCAGGAGGAGGCACTGGCAGGCTGGGAGCCCATGGGAGTAATTGGCCTCATCCTGCCACCCACATTCTCCTTCCTTGAG
ATGATGTGGAGGATTTGCCCTGCCCTGGCTGTGGGCTGCACCGTGGTGGCCCTCGTGCCCCCGGCCTCCCCGGCGCCCCTCCTCCTGGCC
CAGCTGGCGGGGGAGCTGGGCCCCTTCCCGGGAATCCTGAATGTCCTCAGTGGCCCTGCGTCCCTGGTGCCCATCCTGGCCTCCCAGCCT
GGAATCCGGAAGGTGGCCTTCTGCGGAGCCCCGGAGGAAGGGCGTGCCCTTCGACGGAGCCTGGCGGGAGAGTGTGCGGAGCTGGGCCTG
GCGCTGGGGACGGAGTCGCTGCTGCTGCTGACGGACACGGCGGACGTAGACTCGGCCGTGGAGGGTGTCGTGGACGCCGCCTGGTCCGAC
CGCGGCCCGGGTGGCCTCAGGCTCCTCATCCAGGAGTCTGTGTGGGATGAAGCCATGAGACGGCTGCAGGAGCGGATGGGGCGGCTTCGG
AGTGGCCGAGGGCTGGATGGGGCCGTGGACATGGGGGCCCGGGGGGCTGCCGCATGTGACCTGGTCCAGCGCTTTGTGCGTGAGGCCCAG
AGCCAGGGTGCACAGGTGTTCCAGGCTGGTGATGTGCCTTCGGAACGCCCATTCTATCCCCCAACCTTGGTCTCCAACCTGCCCCCAGCC
TCCCCATGTGCCCAGGTGGAGGTGCCGTGGCCTGTGGTCGTGGCCTCCCCCTTCCGCACAGCCAAGGAGGCACTGTTGGTGGCCAACGGG
ACGCCCCGCGGGGGCAGCGCCAGTGTGTGGAGCGAGAGGCTGGGGCAGGCGCTGGAGCTGGGCTATGGGCTCCAGGTGGGCACTGTCTGG
ATCAACGCCCACGGCCTCAGAGACCCTTCGGTGCCCACAGGCGGCTGCAAGGAGAGTGGGTGTTCCTGGCACGGGGGCCCAGACGGGCTG
TATGAGTATCTGCGGCCCTCAGGGACCCCTGCCCGGCTGTCCTGCCTCTCCAAGAACCTGAACTATGACACCTTTGGCCTCGCTGTTCCC
TCAACCCTGCCGGCTGGGCCTGAAATAGGGCCCAGCCCAGCACCCCCCTATGGGCTCTTCGTTGGGGGCCGTTTCCAGGCTCCTGGGGCC
CGAAGCTCCAGGCCCATCCGGGATTCGTCTGGCAACCTCCATGGCTACGTGGCTGAGGGTGGAGCCAAGGACATCCGAGGTGCTGTGGAG
GCCGCTCACCAGGCTTTCCCTGGCTGGGCGGGCCAGTCCCCAGGAGCCCGGGCAGCCCTGCTGTGGGCCCTGGCGGCTGCACTGGAGCGC
CGGAAGTCTACCCTGGCCTCGAGGCTGGAGAGGCAGGGAGCGGAGCTCAAGGCTGCGGAGGCGGAGGTGGAGCTGAGCGCAAGACGACTT
CGGGCGTGGGGGGCCCGGGTGCAGGCCCAAGGCCACACCCTGCAGGTAGCCGGGCTGAGAGGCCCTGTGCTGCGCCTGCGGGAGCCGCTG
GGTGTGCTGGCTGTGGTGTGTCCGGACGAGTGGCCCCTGCTTGCCTTCGTGTCCCTGCTGGCTCCCGCCCTGGCCTACGGCAACACTGTG
GTCATGGTGCCCAGTGCGGCCTGTCCTCTGCTGGCCCTGGAGGTCTGCCAGGACATGGCCACCGTGTTCCCAGCAGGCCTGGCCAACGTG
GTGACAGGAGACCGGGACCATCTGACCCGCTGCCTGGCCTTGCACCAAGACGTCCAGGCCATGTGGTATTTCGGATCAGCCCAGGGTTCC
CAGTTTGTCGAGTGGGCCTCGGCAGGAAACCTCAAACCGGTGTGGGCGAGCAGGGGCTGCCCGCGGGCCTGGGACCAGGAGGCCGAGGGG
GCAGGCCCAGAGCTGGGGCTGCGAGTGGCGCGGACCAAGGCCCTGTGGCTGCCTATGGGGGACTGATGCCTGAGCGCCACCTACTGCATT
TTGGACACCTCACACCAAGGGGAGATGCACCCCACAGACACCTGGGACTTTCCCCTTCTGGTTCCTGTGTCTCCCAATAAACTCTCTGAC
CAACCCTAGCTGTGCTTCTGCGAGAAGAAAGGGTGTAGCAACTTCTGGCAGATATGAGGCTTTTTTCTTTTTTTTTTTTTTTTTTGAGAC
AACGTCTGGCTCTGTCACCCAGGCTGGAGCGCAGTGGCACAATCTCGGCCCACTGCAGCCTCGACCTCTGGGGCTCAAGGGATCCTCATG
CCTCAGCCTCATATGTAGCTGGGGCCACAGACATGCACCACCACACCTGGCTCGAGGCCATTTTAGTTCTGAGGTTGAGCAGCTCAGGAG
CCGGCTCCAGCACGGTGCTGTGTTTGTGAAACAGAGAAAGGGGACCCCCGAGGACCCCAGACAGGGCCTTAGGACTCTCATATCTTCTTG
TCTTCTCCATCTGGTGGCTCTTGCTCTCTGGTTTTCTCTACCTTTTCATGGCCCCAGAATCCATATGCAGTAAAGGAACTCTCTGGAATA

>8785_8785_5_B9D1-ALDH16A1_B9D1_chr17_19263633_ENST00000461069_ALDH16A1_chr19_49961743_ENST00000293350_length(amino acids)=816AA_BP=44
MATASPSVFLLMVNGQVESAQFPEYDDLYCKYCFVYGQDWAPTAAWLDTQDRCLGHYVNGKWLKPEHRNSVPCQDPITGENLASCLQAQA
EDVAAAVEAARMAFKGWSAHPGVVRAQHLTRLAEVIQKHQRLLWTLESLVTGRAVREVRDGDVQLAQQLLHYHAIQASTQEEALAGWEPM
GVIGLILPPTFSFLEMMWRICPALAVGCTVVALVPPASPAPLLLAQLAGELGPFPGILNVLSGPASLVPILASQPGIRKVAFCGAPEEGR
ALRRSLAGECAELGLALGTESLLLLTDTADVDSAVEGVVDAAWSDRGPGGLRLLIQESVWDEAMRRLQERMGRLRSGRGLDGAVDMGARG
AAACDLVQRFVREAQSQGAQVFQAGDVPSERPFYPPTLVSNLPPASPCAQVEVPWPVVVASPFRTAKEALLVANGTPRGGSASVWSERLG
QALELGYGLQVGTVWINAHGLRDPSVPTGGCKESGCSWHGGPDGLYEYLRPSGTPARLSCLSKNLNYDTFGLAVPSTLPAGPEIGPSPAP
PYGLFVGGRFQAPGARSSRPIRDSSGNLHGYVAEGGAKDIRGAVEAAHQAFPGWAGQSPGARAALLWALAAALERRKSTLASRLERQGAE
LKAAEAEVELSARRLRAWGARVQAQGHTLQVAGLRGPVLRLREPLGVLAVVCPDEWPLLAFVSLLAPALAYGNTVVMVPSAACPLLALEV
CQDMATVFPAGLANVVTGDRDHLTRCLALHQDVQAMWYFGSAQGSQFVEWASAGNLKPVWASRGCPRAWDQEAEGAGPELGLRVARTKAL

--------------------------------------------------------------

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Fusion Gene PPI Analysis for B9D1-ALDH16A1


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for B9D1-ALDH16A1


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for B9D1-ALDH16A1


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource