FusionGDB Logo

Home

Download

Statistics

Examples

Help

Contact
Center for Computational Systems Medicine
leaf

Fusion Gene Summary

leaf

Fusion Gene ORF analysis

leaf

Fusion Genomic Features

leaf

Fusion Protein Features

leaf

Fusion Gene Sequence

leaf

Fusion Gene PPI analysis

leaf

Related Drugs

leaf

Related Diseases

Fusion gene:STXBP6-ZNF410 (FusionGDB2 ID:87911)

Fusion Gene Summary for STXBP6-ZNF410

check button Fusion gene summary
Fusion gene informationFusion gene name: STXBP6-ZNF410
Fusion gene ID: 87911
HgeneTgene
Gene symbol

STXBP6

ZNF410

Gene ID

29091

57862

Gene namesyntaxin binding protein 6zinc finger protein 410
SynonymsHSPC156|amisynAPA-1|APA1
Cytomap

14q12

14q24.3

Type of geneprotein-codingprotein-coding
Descriptionsyntaxin-binding protein 6zinc finger protein 410another partner for ARF 1clones 23667 and 23775 zinc finger proteinzinc finger protein APA-1
Modification date2020031320200313
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000323944, ENST00000358326, 
ENST00000396700, ENST00000419632, 
ENST00000546511, ENST00000548724, 
ENST00000550887, ENST00000548369, 
ENST00000334521, ENST00000412490, 
ENST00000442160, ENST00000555044, 
ENST00000556797, ENST00000324593, 
ENST00000540593, 
Fusion gene scores* DoF score4 X 3 X 4=483 X 5 X 3=45
# samples 75
** MAII scorelog2(7/48*10)=0.54432051622381
effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs).
DoF>8 and MAII>0		log2(5/45*10)=0.15200309344505
effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs).
DoF>8 and MAII>0
Context

PubMed: STXBP6 [Title/Abstract] AND ZNF410 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointSTXBP6(25443871)-ZNF410(74370663), # samples:3
Anticipated loss of major functional domain due to fusion event.STXBP6-ZNF410 seems lost the major protein functional domain in Tgene partner, which is a transcription factor due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneSTXBP6

GO:0035542

regulation of SNARE complex assembly

12145319


check buttonFusion gene breakpoints across STXBP6 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across ZNF410 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4SARCTCGA-DX-A6YT-01ASTXBP6chr14

25443871

-ZNF410chr14

74370663

+
ChimerDB4SARCTCGA-DX-A6YTSTXBP6chr14

25443870

-ZNF410chr14

74370662

+
ChimerDB4SARCTCGA-DX-AB32-01ASTXBP6chr14

25443871

-ZNF410chr14

74370663

+
ChimerDB4SARCTCGA-DX-AB32-01ASTXBP6chr14

25443871

-ZNF410chr14

74371605

+


Top

Fusion Gene ORF analysis for STXBP6-ZNF410

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-3UTRENST00000323944ENST00000334521STXBP6chr14

25443871

-ZNF410chr14

74370663

+
5CDS-3UTRENST00000323944ENST00000334521STXBP6chr14

25443870

-ZNF410chr14

74370662

+
5CDS-3UTRENST00000323944ENST00000334521STXBP6chr14

25443871

-ZNF410chr14

74371605

+
5CDS-3UTRENST00000323944ENST00000412490STXBP6chr14

25443871

-ZNF410chr14

74370663

+
5CDS-3UTRENST00000323944ENST00000412490STXBP6chr14

25443870

-ZNF410chr14

74370662

+
5CDS-3UTRENST00000323944ENST00000412490STXBP6chr14

25443871

-ZNF410chr14

74371605

+
5CDS-3UTRENST00000323944ENST00000442160STXBP6chr14

25443871

-ZNF410chr14

74370663

+
5CDS-3UTRENST00000323944ENST00000442160STXBP6chr14

25443870

-ZNF410chr14

74370662

+
5CDS-3UTRENST00000323944ENST00000442160STXBP6chr14

25443871

-ZNF410chr14

74371605

+
5CDS-3UTRENST00000323944ENST00000555044STXBP6chr14

25443871

-ZNF410chr14

74370663

+
5CDS-3UTRENST00000323944ENST00000555044STXBP6chr14

25443870

-ZNF410chr14

74370662

+
5CDS-3UTRENST00000323944ENST00000555044STXBP6chr14

25443871

-ZNF410chr14

74371605

+
5CDS-3UTRENST00000358326ENST00000334521STXBP6chr14

25443871

-ZNF410chr14

74370663

+
5CDS-3UTRENST00000358326ENST00000334521STXBP6chr14

25443870

-ZNF410chr14

74370662

+
5CDS-3UTRENST00000358326ENST00000334521STXBP6chr14

25443871

-ZNF410chr14

74371605

+
5CDS-3UTRENST00000358326ENST00000412490STXBP6chr14

25443871

-ZNF410chr14

74370663

+
5CDS-3UTRENST00000358326ENST00000412490STXBP6chr14

25443870

-ZNF410chr14

74370662

+
5CDS-3UTRENST00000358326ENST00000412490STXBP6chr14

25443871

-ZNF410chr14

74371605

+
5CDS-3UTRENST00000358326ENST00000442160STXBP6chr14

25443871

-ZNF410chr14

74370663

+
5CDS-3UTRENST00000358326ENST00000442160STXBP6chr14

25443870

-ZNF410chr14

74370662

+
5CDS-3UTRENST00000358326ENST00000442160STXBP6chr14

25443871

-ZNF410chr14

74371605

+
5CDS-3UTRENST00000358326ENST00000555044STXBP6chr14

25443871

-ZNF410chr14

74370663

+
5CDS-3UTRENST00000358326ENST00000555044STXBP6chr14

25443870

-ZNF410chr14

74370662

+
5CDS-3UTRENST00000358326ENST00000555044STXBP6chr14

25443871

-ZNF410chr14

74371605

+
5CDS-3UTRENST00000396700ENST00000334521STXBP6chr14

25443871

-ZNF410chr14

74370663

+
5CDS-3UTRENST00000396700ENST00000334521STXBP6chr14

25443870

-ZNF410chr14

74370662

+
5CDS-3UTRENST00000396700ENST00000334521STXBP6chr14

25443871

-ZNF410chr14

74371605

+
5CDS-3UTRENST00000396700ENST00000412490STXBP6chr14

25443871

-ZNF410chr14

74370663

+
5CDS-3UTRENST00000396700ENST00000412490STXBP6chr14

25443870

-ZNF410chr14

74370662

+
5CDS-3UTRENST00000396700ENST00000412490STXBP6chr14

25443871

-ZNF410chr14

74371605

+
5CDS-3UTRENST00000396700ENST00000442160STXBP6chr14

25443871

-ZNF410chr14

74370663

+
5CDS-3UTRENST00000396700ENST00000442160STXBP6chr14

25443870

-ZNF410chr14

74370662

+
5CDS-3UTRENST00000396700ENST00000442160STXBP6chr14

25443871

-ZNF410chr14

74371605

+
5CDS-3UTRENST00000396700ENST00000555044STXBP6chr14

25443871

-ZNF410chr14

74370663

+
5CDS-3UTRENST00000396700ENST00000555044STXBP6chr14

25443870

-ZNF410chr14

74370662

+
5CDS-3UTRENST00000396700ENST00000555044STXBP6chr14

25443871

-ZNF410chr14

74371605

+
5CDS-3UTRENST00000419632ENST00000334521STXBP6chr14

25443871

-ZNF410chr14

74370663

+
5CDS-3UTRENST00000419632ENST00000334521STXBP6chr14

25443870

-ZNF410chr14

74370662

+
5CDS-3UTRENST00000419632ENST00000334521STXBP6chr14

25443871

-ZNF410chr14

74371605

+
5CDS-3UTRENST00000419632ENST00000412490STXBP6chr14

25443871

-ZNF410chr14

74370663

+
5CDS-3UTRENST00000419632ENST00000412490STXBP6chr14

25443870

-ZNF410chr14

74370662

+
5CDS-3UTRENST00000419632ENST00000412490STXBP6chr14

25443871

-ZNF410chr14

74371605

+
5CDS-3UTRENST00000419632ENST00000442160STXBP6chr14

25443871

-ZNF410chr14

74370663

+
5CDS-3UTRENST00000419632ENST00000442160STXBP6chr14

25443870

-ZNF410chr14

74370662

+
5CDS-3UTRENST00000419632ENST00000442160STXBP6chr14

25443871

-ZNF410chr14

74371605

+
5CDS-3UTRENST00000419632ENST00000555044STXBP6chr14

25443871

-ZNF410chr14

74370663

+
5CDS-3UTRENST00000419632ENST00000555044STXBP6chr14

25443870

-ZNF410chr14

74370662

+
5CDS-3UTRENST00000419632ENST00000555044STXBP6chr14

25443871

-ZNF410chr14

74371605

+
5CDS-3UTRENST00000546511ENST00000334521STXBP6chr14

25443871

-ZNF410chr14

74370663

+
5CDS-3UTRENST00000546511ENST00000334521STXBP6chr14

25443870

-ZNF410chr14

74370662

+
5CDS-3UTRENST00000546511ENST00000334521STXBP6chr14

25443871

-ZNF410chr14

74371605

+
5CDS-3UTRENST00000546511ENST00000412490STXBP6chr14

25443871

-ZNF410chr14

74370663

+
5CDS-3UTRENST00000546511ENST00000412490STXBP6chr14

25443870

-ZNF410chr14

74370662

+
5CDS-3UTRENST00000546511ENST00000412490STXBP6chr14

25443871

-ZNF410chr14

74371605

+
5CDS-3UTRENST00000546511ENST00000442160STXBP6chr14

25443871

-ZNF410chr14

74370663

+
5CDS-3UTRENST00000546511ENST00000442160STXBP6chr14

25443870

-ZNF410chr14

74370662

+
5CDS-3UTRENST00000546511ENST00000442160STXBP6chr14

25443871

-ZNF410chr14

74371605

+
5CDS-3UTRENST00000546511ENST00000555044STXBP6chr14

25443871

-ZNF410chr14

74370663

+
5CDS-3UTRENST00000546511ENST00000555044STXBP6chr14

25443870

-ZNF410chr14

74370662

+
5CDS-3UTRENST00000546511ENST00000555044STXBP6chr14

25443871

-ZNF410chr14

74371605

+
5CDS-3UTRENST00000548724ENST00000334521STXBP6chr14

25443871

-ZNF410chr14

74370663

+
5CDS-3UTRENST00000548724ENST00000334521STXBP6chr14

25443870

-ZNF410chr14

74370662

+
5CDS-3UTRENST00000548724ENST00000334521STXBP6chr14

25443871

-ZNF410chr14

74371605

+
5CDS-3UTRENST00000548724ENST00000412490STXBP6chr14

25443871

-ZNF410chr14

74370663

+
5CDS-3UTRENST00000548724ENST00000412490STXBP6chr14

25443870

-ZNF410chr14

74370662

+
5CDS-3UTRENST00000548724ENST00000412490STXBP6chr14

25443871

-ZNF410chr14

74371605

+
5CDS-3UTRENST00000548724ENST00000442160STXBP6chr14

25443871

-ZNF410chr14

74370663

+
5CDS-3UTRENST00000548724ENST00000442160STXBP6chr14

25443870

-ZNF410chr14

74370662

+
5CDS-3UTRENST00000548724ENST00000442160STXBP6chr14

25443871

-ZNF410chr14

74371605

+
5CDS-3UTRENST00000548724ENST00000555044STXBP6chr14

25443871

-ZNF410chr14

74370663

+
5CDS-3UTRENST00000548724ENST00000555044STXBP6chr14

25443870

-ZNF410chr14

74370662

+
5CDS-3UTRENST00000548724ENST00000555044STXBP6chr14

25443871

-ZNF410chr14

74371605

+
5CDS-3UTRENST00000550887ENST00000334521STXBP6chr14

25443871

-ZNF410chr14

74370663

+
5CDS-3UTRENST00000550887ENST00000334521STXBP6chr14

25443870

-ZNF410chr14

74370662

+
5CDS-3UTRENST00000550887ENST00000334521STXBP6chr14

25443871

-ZNF410chr14

74371605

+
5CDS-3UTRENST00000550887ENST00000412490STXBP6chr14

25443871

-ZNF410chr14

74370663

+
5CDS-3UTRENST00000550887ENST00000412490STXBP6chr14

25443870

-ZNF410chr14

74370662

+
5CDS-3UTRENST00000550887ENST00000412490STXBP6chr14

25443871

-ZNF410chr14

74371605

+
5CDS-3UTRENST00000550887ENST00000442160STXBP6chr14

25443871

-ZNF410chr14

74370663

+
5CDS-3UTRENST00000550887ENST00000442160STXBP6chr14

25443870

-ZNF410chr14

74370662

+
5CDS-3UTRENST00000550887ENST00000442160STXBP6chr14

25443871

-ZNF410chr14

74371605

+
5CDS-3UTRENST00000550887ENST00000555044STXBP6chr14

25443871

-ZNF410chr14

74370663

+
5CDS-3UTRENST00000550887ENST00000555044STXBP6chr14

25443870

-ZNF410chr14

74370662

+
5CDS-3UTRENST00000550887ENST00000555044STXBP6chr14

25443871

-ZNF410chr14

74371605

+
5CDS-intronENST00000323944ENST00000556797STXBP6chr14

25443871

-ZNF410chr14

74370663

+
5CDS-intronENST00000323944ENST00000556797STXBP6chr14

25443870

-ZNF410chr14

74370662

+
5CDS-intronENST00000323944ENST00000556797STXBP6chr14

25443871

-ZNF410chr14

74371605

+
5CDS-intronENST00000358326ENST00000556797STXBP6chr14

25443871

-ZNF410chr14

74370663

+
5CDS-intronENST00000358326ENST00000556797STXBP6chr14

25443870

-ZNF410chr14

74370662

+
5CDS-intronENST00000358326ENST00000556797STXBP6chr14

25443871

-ZNF410chr14

74371605

+
5CDS-intronENST00000396700ENST00000556797STXBP6chr14

25443871

-ZNF410chr14

74370663

+
5CDS-intronENST00000396700ENST00000556797STXBP6chr14

25443870

-ZNF410chr14

74370662

+
5CDS-intronENST00000396700ENST00000556797STXBP6chr14

25443871

-ZNF410chr14

74371605

+
5CDS-intronENST00000419632ENST00000556797STXBP6chr14

25443871

-ZNF410chr14

74370663

+
5CDS-intronENST00000419632ENST00000556797STXBP6chr14

25443870

-ZNF410chr14

74370662

+
5CDS-intronENST00000419632ENST00000556797STXBP6chr14

25443871

-ZNF410chr14

74371605

+
5CDS-intronENST00000546511ENST00000556797STXBP6chr14

25443871

-ZNF410chr14

74370663

+
5CDS-intronENST00000546511ENST00000556797STXBP6chr14

25443870

-ZNF410chr14

74370662

+
5CDS-intronENST00000546511ENST00000556797STXBP6chr14

25443871

-ZNF410chr14

74371605

+
5CDS-intronENST00000548724ENST00000556797STXBP6chr14

25443871

-ZNF410chr14

74370663

+
5CDS-intronENST00000548724ENST00000556797STXBP6chr14

25443870

-ZNF410chr14

74370662

+
5CDS-intronENST00000548724ENST00000556797STXBP6chr14

25443871

-ZNF410chr14

74371605

+
5CDS-intronENST00000550887ENST00000556797STXBP6chr14

25443871

-ZNF410chr14

74370663

+
5CDS-intronENST00000550887ENST00000556797STXBP6chr14

25443870

-ZNF410chr14

74370662

+
5CDS-intronENST00000550887ENST00000556797STXBP6chr14

25443871

-ZNF410chr14

74371605

+
Frame-shiftENST00000323944ENST00000324593STXBP6chr14

25443871

-ZNF410chr14

74371605

+
Frame-shiftENST00000323944ENST00000540593STXBP6chr14

25443871

-ZNF410chr14

74371605

+
Frame-shiftENST00000358326ENST00000324593STXBP6chr14

25443871

-ZNF410chr14

74371605

+
Frame-shiftENST00000358326ENST00000540593STXBP6chr14

25443871

-ZNF410chr14

74371605

+
Frame-shiftENST00000396700ENST00000324593STXBP6chr14

25443871

-ZNF410chr14

74370663

+
Frame-shiftENST00000396700ENST00000324593STXBP6chr14

25443870

-ZNF410chr14

74370662

+
Frame-shiftENST00000396700ENST00000324593STXBP6chr14

25443871

-ZNF410chr14

74371605

+
Frame-shiftENST00000396700ENST00000540593STXBP6chr14

25443871

-ZNF410chr14

74370663

+
Frame-shiftENST00000396700ENST00000540593STXBP6chr14

25443870

-ZNF410chr14

74370662

+
Frame-shiftENST00000396700ENST00000540593STXBP6chr14

25443871

-ZNF410chr14

74371605

+
Frame-shiftENST00000419632ENST00000324593STXBP6chr14

25443871

-ZNF410chr14

74370663

+
Frame-shiftENST00000419632ENST00000324593STXBP6chr14

25443870

-ZNF410chr14

74370662

+
Frame-shiftENST00000419632ENST00000324593STXBP6chr14

25443871

-ZNF410chr14

74371605

+
Frame-shiftENST00000419632ENST00000540593STXBP6chr14

25443871

-ZNF410chr14

74370663

+
Frame-shiftENST00000419632ENST00000540593STXBP6chr14

25443870

-ZNF410chr14

74370662

+
Frame-shiftENST00000419632ENST00000540593STXBP6chr14

25443871

-ZNF410chr14

74371605

+
Frame-shiftENST00000546511ENST00000324593STXBP6chr14

25443871

-ZNF410chr14

74371605

+
Frame-shiftENST00000546511ENST00000540593STXBP6chr14

25443871

-ZNF410chr14

74371605

+
Frame-shiftENST00000548724ENST00000324593STXBP6chr14

25443871

-ZNF410chr14

74370663

+
Frame-shiftENST00000548724ENST00000324593STXBP6chr14

25443870

-ZNF410chr14

74370662

+
Frame-shiftENST00000548724ENST00000324593STXBP6chr14

25443871

-ZNF410chr14

74371605

+
Frame-shiftENST00000548724ENST00000540593STXBP6chr14

25443871

-ZNF410chr14

74370663

+
Frame-shiftENST00000548724ENST00000540593STXBP6chr14

25443870

-ZNF410chr14

74370662

+
Frame-shiftENST00000548724ENST00000540593STXBP6chr14

25443871

-ZNF410chr14

74371605

+
Frame-shiftENST00000550887ENST00000324593STXBP6chr14

25443871

-ZNF410chr14

74371605

+
Frame-shiftENST00000550887ENST00000540593STXBP6chr14

25443871

-ZNF410chr14

74371605

+
In-frameENST00000323944ENST00000324593STXBP6chr14

25443871

-ZNF410chr14

74370663

+
In-frameENST00000323944ENST00000324593STXBP6chr14

25443870

-ZNF410chr14

74370662

+
In-frameENST00000323944ENST00000540593STXBP6chr14

25443871

-ZNF410chr14

74370663

+
In-frameENST00000323944ENST00000540593STXBP6chr14

25443870

-ZNF410chr14

74370662

+
In-frameENST00000358326ENST00000324593STXBP6chr14

25443871

-ZNF410chr14

74370663

+
In-frameENST00000358326ENST00000324593STXBP6chr14

25443870

-ZNF410chr14

74370662

+
In-frameENST00000358326ENST00000540593STXBP6chr14

25443871

-ZNF410chr14

74370663

+
In-frameENST00000358326ENST00000540593STXBP6chr14

25443870

-ZNF410chr14

74370662

+
In-frameENST00000546511ENST00000324593STXBP6chr14

25443871

-ZNF410chr14

74370663

+
In-frameENST00000546511ENST00000324593STXBP6chr14

25443870

-ZNF410chr14

74370662

+
In-frameENST00000546511ENST00000540593STXBP6chr14

25443871

-ZNF410chr14

74370663

+
In-frameENST00000546511ENST00000540593STXBP6chr14

25443870

-ZNF410chr14

74370662

+
In-frameENST00000550887ENST00000324593STXBP6chr14

25443871

-ZNF410chr14

74370663

+
In-frameENST00000550887ENST00000324593STXBP6chr14

25443870

-ZNF410chr14

74370662

+
In-frameENST00000550887ENST00000540593STXBP6chr14

25443871

-ZNF410chr14

74370663

+
In-frameENST00000550887ENST00000540593STXBP6chr14

25443870

-ZNF410chr14

74370662

+
intron-3CDSENST00000548369ENST00000324593STXBP6chr14

25443871

-ZNF410chr14

74370663

+
intron-3CDSENST00000548369ENST00000324593STXBP6chr14

25443870

-ZNF410chr14

74370662

+
intron-3CDSENST00000548369ENST00000324593STXBP6chr14

25443871

-ZNF410chr14

74371605

+
intron-3CDSENST00000548369ENST00000540593STXBP6chr14

25443871

-ZNF410chr14

74370663

+
intron-3CDSENST00000548369ENST00000540593STXBP6chr14

25443870

-ZNF410chr14

74370662

+
intron-3CDSENST00000548369ENST00000540593STXBP6chr14

25443871

-ZNF410chr14

74371605

+
intron-3UTRENST00000548369ENST00000334521STXBP6chr14

25443871

-ZNF410chr14

74370663

+
intron-3UTRENST00000548369ENST00000334521STXBP6chr14

25443870

-ZNF410chr14

74370662

+
intron-3UTRENST00000548369ENST00000334521STXBP6chr14

25443871

-ZNF410chr14

74371605

+
intron-3UTRENST00000548369ENST00000412490STXBP6chr14

25443871

-ZNF410chr14

74370663

+
intron-3UTRENST00000548369ENST00000412490STXBP6chr14

25443870

-ZNF410chr14

74370662

+
intron-3UTRENST00000548369ENST00000412490STXBP6chr14

25443871

-ZNF410chr14

74371605

+
intron-3UTRENST00000548369ENST00000442160STXBP6chr14

25443871

-ZNF410chr14

74370663

+
intron-3UTRENST00000548369ENST00000442160STXBP6chr14

25443870

-ZNF410chr14

74370662

+
intron-3UTRENST00000548369ENST00000442160STXBP6chr14

25443871

-ZNF410chr14

74371605

+
intron-3UTRENST00000548369ENST00000555044STXBP6chr14

25443871

-ZNF410chr14

74370663

+
intron-3UTRENST00000548369ENST00000555044STXBP6chr14

25443870

-ZNF410chr14

74370662

+
intron-3UTRENST00000548369ENST00000555044STXBP6chr14

25443871

-ZNF410chr14

74371605

+
intron-intronENST00000548369ENST00000556797STXBP6chr14

25443871

-ZNF410chr14

74370663

+
intron-intronENST00000548369ENST00000556797STXBP6chr14

25443870

-ZNF410chr14

74370662

+
intron-intronENST00000548369ENST00000556797STXBP6chr14

25443871

-ZNF410chr14

74371605

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000323944STXBP6chr1425443871-ENST00000540593ZNF410chr1474370663+151960651462485
ENST00000323944STXBP6chr1425443871-ENST00000324593ZNF410chr1474370663+205960651321438
ENST00000546511STXBP6chr1425443871-ENST00000540593ZNF410chr1474370663+1140227461083345
ENST00000546511STXBP6chr1425443871-ENST00000324593ZNF410chr1474370663+168022746942298
ENST00000550887STXBP6chr1425443871-ENST00000540593ZNF410chr1474370663+13364232421279345
ENST00000550887STXBP6chr1425443871-ENST00000324593ZNF410chr1474370663+18764232421138298
ENST00000358326STXBP6chr1425443871-ENST00000540593ZNF410chr1474370663+1120207141063349
ENST00000358326STXBP6chr1425443871-ENST00000324593ZNF410chr1474370663+166020714922302
ENST00000323944STXBP6chr1425443870-ENST00000540593ZNF410chr1474370662+151960651462485
ENST00000323944STXBP6chr1425443870-ENST00000324593ZNF410chr1474370662+205960651321438
ENST00000546511STXBP6chr1425443870-ENST00000540593ZNF410chr1474370662+1140227461083345
ENST00000546511STXBP6chr1425443870-ENST00000324593ZNF410chr1474370662+168022746942298
ENST00000550887STXBP6chr1425443870-ENST00000540593ZNF410chr1474370662+13364232421279345
ENST00000550887STXBP6chr1425443870-ENST00000324593ZNF410chr1474370662+18764232421138298
ENST00000358326STXBP6chr1425443870-ENST00000540593ZNF410chr1474370662+1120207141063349
ENST00000358326STXBP6chr1425443870-ENST00000324593ZNF410chr1474370662+166020714922302

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000323944ENST00000540593STXBP6chr1425443871-ZNF410chr1474370663+0.032845010.967155
ENST00000323944ENST00000324593STXBP6chr1425443871-ZNF410chr1474370663+0.033721390.9662787
ENST00000546511ENST00000540593STXBP6chr1425443871-ZNF410chr1474370663+0.0074788220.9925211
ENST00000546511ENST00000324593STXBP6chr1425443871-ZNF410chr1474370663+0.0083769880.991623
ENST00000550887ENST00000540593STXBP6chr1425443871-ZNF410chr1474370663+0.0116286190.9883713
ENST00000550887ENST00000324593STXBP6chr1425443871-ZNF410chr1474370663+0.0116614820.9883385
ENST00000358326ENST00000540593STXBP6chr1425443871-ZNF410chr1474370663+0.0130972730.9869027
ENST00000358326ENST00000324593STXBP6chr1425443871-ZNF410chr1474370663+0.0129467040.98705333
ENST00000323944ENST00000540593STXBP6chr1425443870-ZNF410chr1474370662+0.032845010.967155
ENST00000323944ENST00000324593STXBP6chr1425443870-ZNF410chr1474370662+0.033721390.9662787
ENST00000546511ENST00000540593STXBP6chr1425443870-ZNF410chr1474370662+0.0074788220.9925211
ENST00000546511ENST00000324593STXBP6chr1425443870-ZNF410chr1474370662+0.0083769880.991623
ENST00000550887ENST00000540593STXBP6chr1425443870-ZNF410chr1474370662+0.0116286190.9883713
ENST00000550887ENST00000324593STXBP6chr1425443870-ZNF410chr1474370662+0.0116614820.9883385
ENST00000358326ENST00000540593STXBP6chr1425443870-ZNF410chr1474370662+0.0130972730.9869027
ENST00000358326ENST00000324593STXBP6chr1425443870-ZNF410chr1474370662+0.0129467040.98705333

Top

Fusion Genomic Features for STXBP6-ZNF410


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
STXBP6chr1425443870-ZNF410chr1474371604+0.0152880240.984712
STXBP6chr1425443870-ZNF410chr1474370662+0.0002387190.9997613
STXBP6chr1425443870-ZNF410chr1474370662+0.0002387190.9997613
STXBP6chr1425443870-ZNF410chr1474370662+0.0002387190.9997613
STXBP6chr1425443870-ZNF410chr1474371604+0.0152880240.984712
STXBP6chr1425443870-ZNF410chr1474370662+0.0002387190.9997613
STXBP6chr1425443870-ZNF410chr1474370662+0.0002387190.9997613
STXBP6chr1425443870-ZNF410chr1474370662+0.0002387190.9997613

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

Top

Fusion Protein Features for STXBP6-ZNF410


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr14:25443871/chr14:74370663)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneZNF410chr14:25443870chr14:74370662ENST00000324593411219_243193432.0Zinc fingerC2H2-type 1
TgeneZNF410chr14:25443870chr14:74370662ENST00000324593411249_273193432.0Zinc fingerC2H2-type 2
TgeneZNF410chr14:25443870chr14:74370662ENST00000324593411279_303193432.0Zinc fingerC2H2-type 3
TgeneZNF410chr14:25443870chr14:74370662ENST00000324593411309_333193432.0Zinc fingerC2H2-type 4
TgeneZNF410chr14:25443870chr14:74370662ENST00000324593411339_362193432.0Zinc fingerC2H2-type 5
TgeneZNF410chr14:25443870chr14:74370662ENST00000442160514219_243210607.0Zinc fingerC2H2-type 1
TgeneZNF410chr14:25443870chr14:74370662ENST00000442160514249_273210607.0Zinc fingerC2H2-type 2
TgeneZNF410chr14:25443870chr14:74370662ENST00000442160514279_303210607.0Zinc fingerC2H2-type 3
TgeneZNF410chr14:25443870chr14:74370662ENST00000442160514309_333210607.0Zinc fingerC2H2-type 4
TgeneZNF410chr14:25443870chr14:74370662ENST00000442160514339_362210607.0Zinc fingerC2H2-type 5
TgeneZNF410chr14:25443870chr14:74370662ENST00000540593311219_243120406.0Zinc fingerC2H2-type 1
TgeneZNF410chr14:25443870chr14:74370662ENST00000540593311249_273120406.0Zinc fingerC2H2-type 2
TgeneZNF410chr14:25443870chr14:74370662ENST00000540593311279_303120406.0Zinc fingerC2H2-type 3
TgeneZNF410chr14:25443870chr14:74370662ENST00000540593311309_333120406.0Zinc fingerC2H2-type 4
TgeneZNF410chr14:25443870chr14:74370662ENST00000540593311339_362120406.0Zinc fingerC2H2-type 5
TgeneZNF410chr14:25443870chr14:74370662ENST00000555044412219_243193479.0Zinc fingerC2H2-type 1
TgeneZNF410chr14:25443870chr14:74370662ENST00000555044412249_273193479.0Zinc fingerC2H2-type 2
TgeneZNF410chr14:25443870chr14:74370662ENST00000555044412279_303193479.0Zinc fingerC2H2-type 3
TgeneZNF410chr14:25443870chr14:74370662ENST00000555044412309_333193479.0Zinc fingerC2H2-type 4
TgeneZNF410chr14:25443870chr14:74370662ENST00000555044412339_362193479.0Zinc fingerC2H2-type 5
TgeneZNF410chr14:25443871chr14:74370663ENST00000324593411219_243193432.0Zinc fingerC2H2-type 1
TgeneZNF410chr14:25443871chr14:74370663ENST00000324593411249_273193432.0Zinc fingerC2H2-type 2
TgeneZNF410chr14:25443871chr14:74370663ENST00000324593411279_303193432.0Zinc fingerC2H2-type 3
TgeneZNF410chr14:25443871chr14:74370663ENST00000324593411309_333193432.0Zinc fingerC2H2-type 4
TgeneZNF410chr14:25443871chr14:74370663ENST00000324593411339_362193432.0Zinc fingerC2H2-type 5
TgeneZNF410chr14:25443871chr14:74370663ENST00000442160514219_243210607.0Zinc fingerC2H2-type 1
TgeneZNF410chr14:25443871chr14:74370663ENST00000442160514249_273210607.0Zinc fingerC2H2-type 2
TgeneZNF410chr14:25443871chr14:74370663ENST00000442160514279_303210607.0Zinc fingerC2H2-type 3
TgeneZNF410chr14:25443871chr14:74370663ENST00000442160514309_333210607.0Zinc fingerC2H2-type 4
TgeneZNF410chr14:25443871chr14:74370663ENST00000442160514339_362210607.0Zinc fingerC2H2-type 5
TgeneZNF410chr14:25443871chr14:74370663ENST00000540593311219_243120406.0Zinc fingerC2H2-type 1
TgeneZNF410chr14:25443871chr14:74370663ENST00000540593311249_273120406.0Zinc fingerC2H2-type 2
TgeneZNF410chr14:25443871chr14:74370663ENST00000540593311279_303120406.0Zinc fingerC2H2-type 3
TgeneZNF410chr14:25443871chr14:74370663ENST00000540593311309_333120406.0Zinc fingerC2H2-type 4
TgeneZNF410chr14:25443871chr14:74370663ENST00000540593311339_362120406.0Zinc fingerC2H2-type 5
TgeneZNF410chr14:25443871chr14:74370663ENST00000555044412219_243193479.0Zinc fingerC2H2-type 1
TgeneZNF410chr14:25443871chr14:74370663ENST00000555044412249_273193479.0Zinc fingerC2H2-type 2
TgeneZNF410chr14:25443871chr14:74370663ENST00000555044412279_303193479.0Zinc fingerC2H2-type 3
TgeneZNF410chr14:25443871chr14:74370663ENST00000555044412309_333193479.0Zinc fingerC2H2-type 4
TgeneZNF410chr14:25443871chr14:74370663ENST00000555044412339_362193479.0Zinc fingerC2H2-type 5

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneSTXBP6chr14:25443870chr14:74370662ENST00000323944-26151_21051211.0Domainv-SNARE coiled-coil homology
HgeneSTXBP6chr14:25443870chr14:74370662ENST00000358326-26151_21051211.0Domainv-SNARE coiled-coil homology
HgeneSTXBP6chr14:25443870chr14:74370662ENST00000396700-37151_21051211.0Domainv-SNARE coiled-coil homology
HgeneSTXBP6chr14:25443870chr14:74370662ENST00000419632-26151_21051211.0Domainv-SNARE coiled-coil homology
HgeneSTXBP6chr14:25443870chr14:74370662ENST00000546511-26151_21051211.0Domainv-SNARE coiled-coil homology
HgeneSTXBP6chr14:25443870chr14:74370662ENST00000548369-12151_2100109.0Domainv-SNARE coiled-coil homology
HgeneSTXBP6chr14:25443870chr14:74370662ENST00000548724-37151_21051211.0Domainv-SNARE coiled-coil homology
HgeneSTXBP6chr14:25443870chr14:74370662ENST00000550887-37151_21051211.0Domainv-SNARE coiled-coil homology
HgeneSTXBP6chr14:25443871chr14:74370663ENST00000323944-26151_21051211.0Domainv-SNARE coiled-coil homology
HgeneSTXBP6chr14:25443871chr14:74370663ENST00000358326-26151_21051211.0Domainv-SNARE coiled-coil homology
HgeneSTXBP6chr14:25443871chr14:74370663ENST00000396700-37151_21051211.0Domainv-SNARE coiled-coil homology
HgeneSTXBP6chr14:25443871chr14:74370663ENST00000419632-26151_21051211.0Domainv-SNARE coiled-coil homology
HgeneSTXBP6chr14:25443871chr14:74370663ENST00000546511-26151_21051211.0Domainv-SNARE coiled-coil homology
HgeneSTXBP6chr14:25443871chr14:74370663ENST00000548369-12151_2100109.0Domainv-SNARE coiled-coil homology
HgeneSTXBP6chr14:25443871chr14:74370663ENST00000548724-37151_21051211.0Domainv-SNARE coiled-coil homology
HgeneSTXBP6chr14:25443871chr14:74370663ENST00000550887-37151_21051211.0Domainv-SNARE coiled-coil homology


Top

Fusion Gene Sequence for STXBP6-ZNF410


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>87911_87911_1_STXBP6-ZNF410_STXBP6_chr14_25443870_ENST00000323944_ZNF410_chr14_74370662_ENST00000324593_length(transcript)=2059nt_BP=606nt
GAGGCCTGGGGCGGGTCGCGGGTCCCGGCCCCCAGCCCCCAGCCCCTAGCCGCTGCTCTTTGCCCCGGGCCAGGGCGCTCGGGCTCGCCC
ACGGCGGCACTGAGCATGCTCAGAGGCGGCCGCGCGGGCAGGTTTGCTTCGCAGGCGCTCGCACTCGGCGGCGGGCGGGCGCGCGGCTGC
AGCTGGAGCTCCAGCGCCCGGAGTTGGAGTTGCCGGGAGTTTCCCCCCAACCCCTCCCTTTTCGCGCGCGGCAGCAGGAGCCGGCGCGGG
AGCCGCGAGCGGCGGCGAGCCAGCACCCGGGCCGGCTAAGCCTTGTCCGGAGCCCGGAGCCCCGCGCGGGGCAGCCCCCCGGGGAGGAGC
CTCGTGCTCTGGGACGCGTGCCGCGCACTGGCACGGCAGGGGCGCGAGCCAGGCTGCACGATTCACTGCGTGCTGTCCTCACTTGTTCTA
CAATGAGTGCCAAATCTGCTATCAGCAAGGAAATTTTTGCACCTCTTGATGAAAGGATGCTGGGAGCTGTCCAAGTCAAGAGGAGGACAA
AGAAAAAGATTCCTTTCTTGGCAACTGGAGGTCAAGGCGAATATTTAACTTATATCTGCCTGTCAGGAGAAAATGTCCACCTTGGTTCTG
GTGATGGGCAGTCAAAAGATTCTGGGCCCCTTCCTCAAGTGGAAAAGAAGCTCAAGTGTACAGTTGAAGGTTGTGACCGGACATTTGTAT
GGCCAGCTCACTTTAAATACCACCTCAAGACTCATCGAAATGACCGCTCCTTCATCTGTCCTGCAGAAGGTTGTGGGAAAAGCTTCTATG
TGCTGCAGAGGCTGAAGGTGCACATGAGGACCCACAATGGAGAGAAGCCCTTTATGTGCCATGAGTCTGGCTGTGGTAAGCAGTTTACTA
CAGCTGGAAACCTGAAGAACCACCGGCGCATCCACACAGGAGAGAAACCTTTCCTTTGTGAAGCCCAAGGATGTGGCCGTTCCTTTGCTG
AGTATTCTAGCCTCCGAAAACATCTGGTGGTTCACTCAGGAGAGAAGCCTCATCAGTGCCAAGTCTGTGGGAAGACCTTCTCTCAGAGTG
GAAGCAGGAATGTGCATATGAGAAAGCATCACCTGCAGCTGGGAGCAGCTGGGAGTCAAGAGCAGGAGCAAACTGAGGTGCTTGCTGAAG
GATCCCCACGTTCCCTGTCTTCAGTGCCTGATGTGACACATCACCTGGTGACCATGCAGTCAGGGAGGCAATCATATGAAGTTTCTGTCT
TAACTGCAGTAAATCCACAAGAGTTACTAAACCAAGGAGATTTAACTGAAAGACGGACATGAGCGTGGGTGCTGACTCCTGGAAGAGCAA
CTCTATCTGATCTCAAAATGCGTATACTGGGAACAGGATGCCTTAGCCCACAACAGAACCAGAATGAATCTTTGAAGGCACAAGACTCTG
CTTTTGCCACTCTTCCTCTTTCCTGGTATAGAAGATGGATGTAGGAGAGCTTCTTTTCTAACTACCATCTGATCAGACAAGGAATGAAGC
AATGACTGTGGGCTGGGAAACTGTACCTACCTCTCTTCCCACTGCAAATTTCTGGGATAGACCAAAAGTGAATTTGATTATGTGTTGGCT
GAAGTTCTTCATTCTGACTGTTGAGGGGAGGTTTTCCTTTGAAGAGTTTTCATCCCAGACTCAGCTGTCTTTTCACATGGATGAAATAAT
TCCTGCTACCAACAACAGAGCTTCACCAGGAAGTTGAGTTTTCAAGATGCCTTGTTGCTTTGAAGAAGGGAGTGATGTCAATTCTCTTGT
TACATTCTCCCTTTAGCAACCTGAGTAAGAGACTCTCTGCCACTGGGCTGCAAAAAAATAAATTACTTGAATCTCCCCTTGGCCCAGGCT
GAGGTACTATCTTGTCCTATACACTTCTACTTGGTCACTTTGCTTTCTTCGTTAATGGAACATACAGTAGCATGTTAAGAGGGATTTCAT

>87911_87911_1_STXBP6-ZNF410_STXBP6_chr14_25443870_ENST00000323944_ZNF410_chr14_74370662_ENST00000324593_length(amino acids)=438AA_BP=200
MGRVAGPGPQPPAPSRCSLPRARALGLAHGGTEHAQRRPRGQVCFAGARTRRRAGARLQLELQRPELELPGVSPQPLPFRARQQEPAREP
RAAASQHPGRLSLVRSPEPRAGQPPGEEPRALGRVPRTGTAGARARLHDSLRAVLTCSTMSAKSAISKEIFAPLDERMLGAVQVKRRTKK
KIPFLATGGQGEYLTYICLSGENVHLGSGDGQSKDSGPLPQVEKKLKCTVEGCDRTFVWPAHFKYHLKTHRNDRSFICPAEGCGKSFYVL
QRLKVHMRTHNGEKPFMCHESGCGKQFTTAGNLKNHRRIHTGEKPFLCEAQGCGRSFAEYSSLRKHLVVHSGEKPHQCQVCGKTFSQSGS

--------------------------------------------------------------
>87911_87911_2_STXBP6-ZNF410_STXBP6_chr14_25443870_ENST00000323944_ZNF410_chr14_74370662_ENST00000540593_length(transcript)=1519nt_BP=606nt
GAGGCCTGGGGCGGGTCGCGGGTCCCGGCCCCCAGCCCCCAGCCCCTAGCCGCTGCTCTTTGCCCCGGGCCAGGGCGCTCGGGCTCGCCC
ACGGCGGCACTGAGCATGCTCAGAGGCGGCCGCGCGGGCAGGTTTGCTTCGCAGGCGCTCGCACTCGGCGGCGGGCGGGCGCGCGGCTGC
AGCTGGAGCTCCAGCGCCCGGAGTTGGAGTTGCCGGGAGTTTCCCCCCAACCCCTCCCTTTTCGCGCGCGGCAGCAGGAGCCGGCGCGGG
AGCCGCGAGCGGCGGCGAGCCAGCACCCGGGCCGGCTAAGCCTTGTCCGGAGCCCGGAGCCCCGCGCGGGGCAGCCCCCCGGGGAGGAGC
CTCGTGCTCTGGGACGCGTGCCGCGCACTGGCACGGCAGGGGCGCGAGCCAGGCTGCACGATTCACTGCGTGCTGTCCTCACTTGTTCTA
CAATGAGTGCCAAATCTGCTATCAGCAAGGAAATTTTTGCACCTCTTGATGAAAGGATGCTGGGAGCTGTCCAAGTCAAGAGGAGGACAA
AGAAAAAGATTCCTTTCTTGGCAACTGGAGGTCAAGGCGAATATTTAACTTATATCTGCCTGTCAGGAGAAAATGTCCACCTTGGTTCTG
GTGATGGGCAGTCAAAAGATTCTGGGCCCCTTCCTCAAGTGGAAAAGAAGCTCAAGTGTACAGTTGAAGGTTGTGACCGGACATTTGTAT
GGCCAGCTCACTTTAAATACCACCTCAAGACTCATCGAAATGACCGCTCCTTCATCTGTCCTGCAGAAGGTTGTGGGAAAAGCTTCTATG
TGCTGCAGAGGCTGAAGGTGCACATGAGGACCCACAATGGAGAGAAGCCCTTTATGTGCCATGAGTCTGGCTGTGGTAAGCAGTTTACTA
CAGCTGGAAACCTGAAGAACCACCGGCGCATCCACACAGGAGAGAAACCTTTCCTTTGTGAAGCCCAAGGATGTGGCCGTTCCTTTGCTG
AGTATTCTAGCCTCCGAAAACATCTGGTGGTTCACTCAGGAGAGAAGCCTCATCAGTGCCAAGTCTGTGGGAAGACCTTCTCTCAGAGTG
GAAGCAGGAATGTGCATATGAGAAAGCATCACCTGCAGCTGGGAGCAGCTGGGAGTCAAGAGCAGGAGCAAACTGCTGAGCCACTAATGG
GCAGTAGTTTGCTTGAAGAGGCTTCAGTACCCAGTAAAAACCTGGTGTCTATGAATTCCCAGCCCAGCCTTGGTGGAGAGTCCTTGAACC
TACCAAATACCAATTCTATCCTGGGAGTTGATGATGAGGTGCTTGCTGAAGGATCCCCACGTTCCCTGTCTTCAGTGCCTGATGTGACAC
ATCACCTGGTGACCATGCAGTCAGGGAGGCAATCATATGAAGTTTCTGTCTTAACTGCAGTAAATCCACAAGAGTTACTAAACCAAGGAG

>87911_87911_2_STXBP6-ZNF410_STXBP6_chr14_25443870_ENST00000323944_ZNF410_chr14_74370662_ENST00000540593_length(amino acids)=485AA_BP=200
MGRVAGPGPQPPAPSRCSLPRARALGLAHGGTEHAQRRPRGQVCFAGARTRRRAGARLQLELQRPELELPGVSPQPLPFRARQQEPAREP
RAAASQHPGRLSLVRSPEPRAGQPPGEEPRALGRVPRTGTAGARARLHDSLRAVLTCSTMSAKSAISKEIFAPLDERMLGAVQVKRRTKK
KIPFLATGGQGEYLTYICLSGENVHLGSGDGQSKDSGPLPQVEKKLKCTVEGCDRTFVWPAHFKYHLKTHRNDRSFICPAEGCGKSFYVL
QRLKVHMRTHNGEKPFMCHESGCGKQFTTAGNLKNHRRIHTGEKPFLCEAQGCGRSFAEYSSLRKHLVVHSGEKPHQCQVCGKTFSQSGS
RNVHMRKHHLQLGAAGSQEQEQTAEPLMGSSLLEEASVPSKNLVSMNSQPSLGGESLNLPNTNSILGVDDEVLAEGSPRSLSSVPDVTHH

--------------------------------------------------------------
>87911_87911_3_STXBP6-ZNF410_STXBP6_chr14_25443870_ENST00000358326_ZNF410_chr14_74370662_ENST00000324593_length(transcript)=1660nt_BP=207nt
GGGCGCGAGCCAGGCTGCACGATTCACTGCGTGCTGTCCTCACTTGTTCTACAATGAGTGCCAAATCTGCTATCAGCAAGGAAATTTTTG
CACCTCTTGATGAAAGGATGCTGGGAGCTGTCCAAGTCAAGAGGAGGACAAAGAAAAAGATTCCTTTCTTGGCAACTGGAGGTCAAGGCG
AATATTTAACTTATATCTGCCTGTCAGGAGAAAATGTCCACCTTGGTTCTGGTGATGGGCAGTCAAAAGATTCTGGGCCCCTTCCTCAAG
TGGAAAAGAAGCTCAAGTGTACAGTTGAAGGTTGTGACCGGACATTTGTATGGCCAGCTCACTTTAAATACCACCTCAAGACTCATCGAA
ATGACCGCTCCTTCATCTGTCCTGCAGAAGGTTGTGGGAAAAGCTTCTATGTGCTGCAGAGGCTGAAGGTGCACATGAGGACCCACAATG
GAGAGAAGCCCTTTATGTGCCATGAGTCTGGCTGTGGTAAGCAGTTTACTACAGCTGGAAACCTGAAGAACCACCGGCGCATCCACACAG
GAGAGAAACCTTTCCTTTGTGAAGCCCAAGGATGTGGCCGTTCCTTTGCTGAGTATTCTAGCCTCCGAAAACATCTGGTGGTTCACTCAG
GAGAGAAGCCTCATCAGTGCCAAGTCTGTGGGAAGACCTTCTCTCAGAGTGGAAGCAGGAATGTGCATATGAGAAAGCATCACCTGCAGC
TGGGAGCAGCTGGGAGTCAAGAGCAGGAGCAAACTGAGGTGCTTGCTGAAGGATCCCCACGTTCCCTGTCTTCAGTGCCTGATGTGACAC
ATCACCTGGTGACCATGCAGTCAGGGAGGCAATCATATGAAGTTTCTGTCTTAACTGCAGTAAATCCACAAGAGTTACTAAACCAAGGAG
ATTTAACTGAAAGACGGACATGAGCGTGGGTGCTGACTCCTGGAAGAGCAACTCTATCTGATCTCAAAATGCGTATACTGGGAACAGGAT
GCCTTAGCCCACAACAGAACCAGAATGAATCTTTGAAGGCACAAGACTCTGCTTTTGCCACTCTTCCTCTTTCCTGGTATAGAAGATGGA
TGTAGGAGAGCTTCTTTTCTAACTACCATCTGATCAGACAAGGAATGAAGCAATGACTGTGGGCTGGGAAACTGTACCTACCTCTCTTCC
CACTGCAAATTTCTGGGATAGACCAAAAGTGAATTTGATTATGTGTTGGCTGAAGTTCTTCATTCTGACTGTTGAGGGGAGGTTTTCCTT
TGAAGAGTTTTCATCCCAGACTCAGCTGTCTTTTCACATGGATGAAATAATTCCTGCTACCAACAACAGAGCTTCACCAGGAAGTTGAGT
TTTCAAGATGCCTTGTTGCTTTGAAGAAGGGAGTGATGTCAATTCTCTTGTTACATTCTCCCTTTAGCAACCTGAGTAAGAGACTCTCTG
CCACTGGGCTGCAAAAAAATAAATTACTTGAATCTCCCCTTGGCCCAGGCTGAGGTACTATCTTGTCCTATACACTTCTACTTGGTCACT
TTGCTTTCTTCGTTAATGGAACATACAGTAGCATGTTAAGAGGGATTTCATGTTTTTGTTTTTTTAAAGTTAAAAATTACATGATGCAGA

>87911_87911_3_STXBP6-ZNF410_STXBP6_chr14_25443870_ENST00000358326_ZNF410_chr14_74370662_ENST00000324593_length(amino acids)=302AA_BP=64
MHDSLRAVLTCSTMSAKSAISKEIFAPLDERMLGAVQVKRRTKKKIPFLATGGQGEYLTYICLSGENVHLGSGDGQSKDSGPLPQVEKKL
KCTVEGCDRTFVWPAHFKYHLKTHRNDRSFICPAEGCGKSFYVLQRLKVHMRTHNGEKPFMCHESGCGKQFTTAGNLKNHRRIHTGEKPF
LCEAQGCGRSFAEYSSLRKHLVVHSGEKPHQCQVCGKTFSQSGSRNVHMRKHHLQLGAAGSQEQEQTEVLAEGSPRSLSSVPDVTHHLVT

--------------------------------------------------------------
>87911_87911_4_STXBP6-ZNF410_STXBP6_chr14_25443870_ENST00000358326_ZNF410_chr14_74370662_ENST00000540593_length(transcript)=1120nt_BP=207nt
GGGCGCGAGCCAGGCTGCACGATTCACTGCGTGCTGTCCTCACTTGTTCTACAATGAGTGCCAAATCTGCTATCAGCAAGGAAATTTTTG
CACCTCTTGATGAAAGGATGCTGGGAGCTGTCCAAGTCAAGAGGAGGACAAAGAAAAAGATTCCTTTCTTGGCAACTGGAGGTCAAGGCG
AATATTTAACTTATATCTGCCTGTCAGGAGAAAATGTCCACCTTGGTTCTGGTGATGGGCAGTCAAAAGATTCTGGGCCCCTTCCTCAAG
TGGAAAAGAAGCTCAAGTGTACAGTTGAAGGTTGTGACCGGACATTTGTATGGCCAGCTCACTTTAAATACCACCTCAAGACTCATCGAA
ATGACCGCTCCTTCATCTGTCCTGCAGAAGGTTGTGGGAAAAGCTTCTATGTGCTGCAGAGGCTGAAGGTGCACATGAGGACCCACAATG
GAGAGAAGCCCTTTATGTGCCATGAGTCTGGCTGTGGTAAGCAGTTTACTACAGCTGGAAACCTGAAGAACCACCGGCGCATCCACACAG
GAGAGAAACCTTTCCTTTGTGAAGCCCAAGGATGTGGCCGTTCCTTTGCTGAGTATTCTAGCCTCCGAAAACATCTGGTGGTTCACTCAG
GAGAGAAGCCTCATCAGTGCCAAGTCTGTGGGAAGACCTTCTCTCAGAGTGGAAGCAGGAATGTGCATATGAGAAAGCATCACCTGCAGC
TGGGAGCAGCTGGGAGTCAAGAGCAGGAGCAAACTGCTGAGCCACTAATGGGCAGTAGTTTGCTTGAAGAGGCTTCAGTACCCAGTAAAA
ACCTGGTGTCTATGAATTCCCAGCCCAGCCTTGGTGGAGAGTCCTTGAACCTACCAAATACCAATTCTATCCTGGGAGTTGATGATGAGG
TGCTTGCTGAAGGATCCCCACGTTCCCTGTCTTCAGTGCCTGATGTGACACATCACCTGGTGACCATGCAGTCAGGGAGGCAATCATATG
AAGTTTCTGTCTTAACTGCAGTAAATCCACAAGAGTTACTAAACCAAGGAGATTTAACTGAAAGACGGACATGAGCGTGGGTGCTGACTC

>87911_87911_4_STXBP6-ZNF410_STXBP6_chr14_25443870_ENST00000358326_ZNF410_chr14_74370662_ENST00000540593_length(amino acids)=349AA_BP=64
MHDSLRAVLTCSTMSAKSAISKEIFAPLDERMLGAVQVKRRTKKKIPFLATGGQGEYLTYICLSGENVHLGSGDGQSKDSGPLPQVEKKL
KCTVEGCDRTFVWPAHFKYHLKTHRNDRSFICPAEGCGKSFYVLQRLKVHMRTHNGEKPFMCHESGCGKQFTTAGNLKNHRRIHTGEKPF
LCEAQGCGRSFAEYSSLRKHLVVHSGEKPHQCQVCGKTFSQSGSRNVHMRKHHLQLGAAGSQEQEQTAEPLMGSSLLEEASVPSKNLVSM

--------------------------------------------------------------
>87911_87911_5_STXBP6-ZNF410_STXBP6_chr14_25443870_ENST00000546511_ZNF410_chr14_74370662_ENST00000324593_length(transcript)=1680nt_BP=227nt
ATTACGCTTCCCTAGGGACTGGGTGGGAGAGAATAGGATCGATTCACTGCGTGCTGTCCTCACTTGTTCTACAATGAGTGCCAAATCTGC
TATCAGCAAGGAAATTTTTGCACCTCTTGATGAAAGGATGCTGGGAGCTGTCCAAGTCAAGAGGAGGACAAAGAAAAAGATTCCTTTCTT
GGCAACTGGAGGTCAAGGCGAATATTTAACTTATATCTGCCTGTCAGGAGAAAATGTCCACCTTGGTTCTGGTGATGGGCAGTCAAAAGA
TTCTGGGCCCCTTCCTCAAGTGGAAAAGAAGCTCAAGTGTACAGTTGAAGGTTGTGACCGGACATTTGTATGGCCAGCTCACTTTAAATA
CCACCTCAAGACTCATCGAAATGACCGCTCCTTCATCTGTCCTGCAGAAGGTTGTGGGAAAAGCTTCTATGTGCTGCAGAGGCTGAAGGT
GCACATGAGGACCCACAATGGAGAGAAGCCCTTTATGTGCCATGAGTCTGGCTGTGGTAAGCAGTTTACTACAGCTGGAAACCTGAAGAA
CCACCGGCGCATCCACACAGGAGAGAAACCTTTCCTTTGTGAAGCCCAAGGATGTGGCCGTTCCTTTGCTGAGTATTCTAGCCTCCGAAA
ACATCTGGTGGTTCACTCAGGAGAGAAGCCTCATCAGTGCCAAGTCTGTGGGAAGACCTTCTCTCAGAGTGGAAGCAGGAATGTGCATAT
GAGAAAGCATCACCTGCAGCTGGGAGCAGCTGGGAGTCAAGAGCAGGAGCAAACTGAGGTGCTTGCTGAAGGATCCCCACGTTCCCTGTC
TTCAGTGCCTGATGTGACACATCACCTGGTGACCATGCAGTCAGGGAGGCAATCATATGAAGTTTCTGTCTTAACTGCAGTAAATCCACA
AGAGTTACTAAACCAAGGAGATTTAACTGAAAGACGGACATGAGCGTGGGTGCTGACTCCTGGAAGAGCAACTCTATCTGATCTCAAAAT
GCGTATACTGGGAACAGGATGCCTTAGCCCACAACAGAACCAGAATGAATCTTTGAAGGCACAAGACTCTGCTTTTGCCACTCTTCCTCT
TTCCTGGTATAGAAGATGGATGTAGGAGAGCTTCTTTTCTAACTACCATCTGATCAGACAAGGAATGAAGCAATGACTGTGGGCTGGGAA
ACTGTACCTACCTCTCTTCCCACTGCAAATTTCTGGGATAGACCAAAAGTGAATTTGATTATGTGTTGGCTGAAGTTCTTCATTCTGACT
GTTGAGGGGAGGTTTTCCTTTGAAGAGTTTTCATCCCAGACTCAGCTGTCTTTTCACATGGATGAAATAATTCCTGCTACCAACAACAGA
GCTTCACCAGGAAGTTGAGTTTTCAAGATGCCTTGTTGCTTTGAAGAAGGGAGTGATGTCAATTCTCTTGTTACATTCTCCCTTTAGCAA
CCTGAGTAAGAGACTCTCTGCCACTGGGCTGCAAAAAAATAAATTACTTGAATCTCCCCTTGGCCCAGGCTGAGGTACTATCTTGTCCTA
TACACTTCTACTTGGTCACTTTGCTTTCTTCGTTAATGGAACATACAGTAGCATGTTAAGAGGGATTTCATGTTTTTGTTTTTTTAAAGT

>87911_87911_5_STXBP6-ZNF410_STXBP6_chr14_25443870_ENST00000546511_ZNF410_chr14_74370662_ENST00000324593_length(amino acids)=298AA_BP=60
MRAVLTCSTMSAKSAISKEIFAPLDERMLGAVQVKRRTKKKIPFLATGGQGEYLTYICLSGENVHLGSGDGQSKDSGPLPQVEKKLKCTV
EGCDRTFVWPAHFKYHLKTHRNDRSFICPAEGCGKSFYVLQRLKVHMRTHNGEKPFMCHESGCGKQFTTAGNLKNHRRIHTGEKPFLCEA
QGCGRSFAEYSSLRKHLVVHSGEKPHQCQVCGKTFSQSGSRNVHMRKHHLQLGAAGSQEQEQTEVLAEGSPRSLSSVPDVTHHLVTMQSG

--------------------------------------------------------------
>87911_87911_6_STXBP6-ZNF410_STXBP6_chr14_25443870_ENST00000546511_ZNF410_chr14_74370662_ENST00000540593_length(transcript)=1140nt_BP=227nt
ATTACGCTTCCCTAGGGACTGGGTGGGAGAGAATAGGATCGATTCACTGCGTGCTGTCCTCACTTGTTCTACAATGAGTGCCAAATCTGC
TATCAGCAAGGAAATTTTTGCACCTCTTGATGAAAGGATGCTGGGAGCTGTCCAAGTCAAGAGGAGGACAAAGAAAAAGATTCCTTTCTT
GGCAACTGGAGGTCAAGGCGAATATTTAACTTATATCTGCCTGTCAGGAGAAAATGTCCACCTTGGTTCTGGTGATGGGCAGTCAAAAGA
TTCTGGGCCCCTTCCTCAAGTGGAAAAGAAGCTCAAGTGTACAGTTGAAGGTTGTGACCGGACATTTGTATGGCCAGCTCACTTTAAATA
CCACCTCAAGACTCATCGAAATGACCGCTCCTTCATCTGTCCTGCAGAAGGTTGTGGGAAAAGCTTCTATGTGCTGCAGAGGCTGAAGGT
GCACATGAGGACCCACAATGGAGAGAAGCCCTTTATGTGCCATGAGTCTGGCTGTGGTAAGCAGTTTACTACAGCTGGAAACCTGAAGAA
CCACCGGCGCATCCACACAGGAGAGAAACCTTTCCTTTGTGAAGCCCAAGGATGTGGCCGTTCCTTTGCTGAGTATTCTAGCCTCCGAAA
ACATCTGGTGGTTCACTCAGGAGAGAAGCCTCATCAGTGCCAAGTCTGTGGGAAGACCTTCTCTCAGAGTGGAAGCAGGAATGTGCATAT
GAGAAAGCATCACCTGCAGCTGGGAGCAGCTGGGAGTCAAGAGCAGGAGCAAACTGCTGAGCCACTAATGGGCAGTAGTTTGCTTGAAGA
GGCTTCAGTACCCAGTAAAAACCTGGTGTCTATGAATTCCCAGCCCAGCCTTGGTGGAGAGTCCTTGAACCTACCAAATACCAATTCTAT
CCTGGGAGTTGATGATGAGGTGCTTGCTGAAGGATCCCCACGTTCCCTGTCTTCAGTGCCTGATGTGACACATCACCTGGTGACCATGCA
GTCAGGGAGGCAATCATATGAAGTTTCTGTCTTAACTGCAGTAAATCCACAAGAGTTACTAAACCAAGGAGATTTAACTGAAAGACGGAC

>87911_87911_6_STXBP6-ZNF410_STXBP6_chr14_25443870_ENST00000546511_ZNF410_chr14_74370662_ENST00000540593_length(amino acids)=345AA_BP=60
MRAVLTCSTMSAKSAISKEIFAPLDERMLGAVQVKRRTKKKIPFLATGGQGEYLTYICLSGENVHLGSGDGQSKDSGPLPQVEKKLKCTV
EGCDRTFVWPAHFKYHLKTHRNDRSFICPAEGCGKSFYVLQRLKVHMRTHNGEKPFMCHESGCGKQFTTAGNLKNHRRIHTGEKPFLCEA
QGCGRSFAEYSSLRKHLVVHSGEKPHQCQVCGKTFSQSGSRNVHMRKHHLQLGAAGSQEQEQTAEPLMGSSLLEEASVPSKNLVSMNSQP

--------------------------------------------------------------
>87911_87911_7_STXBP6-ZNF410_STXBP6_chr14_25443870_ENST00000550887_ZNF410_chr14_74370662_ENST00000324593_length(transcript)=1876nt_BP=423nt
TTTCCTGTTTAGAAAGTTCTGCTCCTTCATAAGGACCTTGAAGTACTAGGAGGAAAGGTGCTTTGTGTGTGGAGTTTTCCATGAAGTGCA
GTCCCAACTAAAAGGCTGCGTTAAAGGCTAGAGTAGTGCAGTGGCGTGATCTCAGCTCACTCCAGCCTCTGCCTCCCGGGCTCAAGTGAC
CCACCTGCCTCAGCCTCCCAAGTAGCTGGGACAACAGATGTGAGCCACCACACCCAGATTCACTGCGTGCTGTCCTCACTTGTTCTACAA
TGAGTGCCAAATCTGCTATCAGCAAGGAAATTTTTGCACCTCTTGATGAAAGGATGCTGGGAGCTGTCCAAGTCAAGAGGAGGACAAAGA
AAAAGATTCCTTTCTTGGCAACTGGAGGTCAAGGCGAATATTTAACTTATATCTGCCTGTCAGGAGAAAATGTCCACCTTGGTTCTGGTG
ATGGGCAGTCAAAAGATTCTGGGCCCCTTCCTCAAGTGGAAAAGAAGCTCAAGTGTACAGTTGAAGGTTGTGACCGGACATTTGTATGGC
CAGCTCACTTTAAATACCACCTCAAGACTCATCGAAATGACCGCTCCTTCATCTGTCCTGCAGAAGGTTGTGGGAAAAGCTTCTATGTGC
TGCAGAGGCTGAAGGTGCACATGAGGACCCACAATGGAGAGAAGCCCTTTATGTGCCATGAGTCTGGCTGTGGTAAGCAGTTTACTACAG
CTGGAAACCTGAAGAACCACCGGCGCATCCACACAGGAGAGAAACCTTTCCTTTGTGAAGCCCAAGGATGTGGCCGTTCCTTTGCTGAGT
ATTCTAGCCTCCGAAAACATCTGGTGGTTCACTCAGGAGAGAAGCCTCATCAGTGCCAAGTCTGTGGGAAGACCTTCTCTCAGAGTGGAA
GCAGGAATGTGCATATGAGAAAGCATCACCTGCAGCTGGGAGCAGCTGGGAGTCAAGAGCAGGAGCAAACTGAGGTGCTTGCTGAAGGAT
CCCCACGTTCCCTGTCTTCAGTGCCTGATGTGACACATCACCTGGTGACCATGCAGTCAGGGAGGCAATCATATGAAGTTTCTGTCTTAA
CTGCAGTAAATCCACAAGAGTTACTAAACCAAGGAGATTTAACTGAAAGACGGACATGAGCGTGGGTGCTGACTCCTGGAAGAGCAACTC
TATCTGATCTCAAAATGCGTATACTGGGAACAGGATGCCTTAGCCCACAACAGAACCAGAATGAATCTTTGAAGGCACAAGACTCTGCTT
TTGCCACTCTTCCTCTTTCCTGGTATAGAAGATGGATGTAGGAGAGCTTCTTTTCTAACTACCATCTGATCAGACAAGGAATGAAGCAAT
GACTGTGGGCTGGGAAACTGTACCTACCTCTCTTCCCACTGCAAATTTCTGGGATAGACCAAAAGTGAATTTGATTATGTGTTGGCTGAA
GTTCTTCATTCTGACTGTTGAGGGGAGGTTTTCCTTTGAAGAGTTTTCATCCCAGACTCAGCTGTCTTTTCACATGGATGAAATAATTCC
TGCTACCAACAACAGAGCTTCACCAGGAAGTTGAGTTTTCAAGATGCCTTGTTGCTTTGAAGAAGGGAGTGATGTCAATTCTCTTGTTAC
ATTCTCCCTTTAGCAACCTGAGTAAGAGACTCTCTGCCACTGGGCTGCAAAAAAATAAATTACTTGAATCTCCCCTTGGCCCAGGCTGAG
GTACTATCTTGTCCTATACACTTCTACTTGGTCACTTTGCTTTCTTCGTTAATGGAACATACAGTAGCATGTTAAGAGGGATTTCATGTT

>87911_87911_7_STXBP6-ZNF410_STXBP6_chr14_25443870_ENST00000550887_ZNF410_chr14_74370662_ENST00000324593_length(amino acids)=298AA_BP=60
MRAVLTCSTMSAKSAISKEIFAPLDERMLGAVQVKRRTKKKIPFLATGGQGEYLTYICLSGENVHLGSGDGQSKDSGPLPQVEKKLKCTV
EGCDRTFVWPAHFKYHLKTHRNDRSFICPAEGCGKSFYVLQRLKVHMRTHNGEKPFMCHESGCGKQFTTAGNLKNHRRIHTGEKPFLCEA
QGCGRSFAEYSSLRKHLVVHSGEKPHQCQVCGKTFSQSGSRNVHMRKHHLQLGAAGSQEQEQTEVLAEGSPRSLSSVPDVTHHLVTMQSG

--------------------------------------------------------------
>87911_87911_8_STXBP6-ZNF410_STXBP6_chr14_25443870_ENST00000550887_ZNF410_chr14_74370662_ENST00000540593_length(transcript)=1336nt_BP=423nt
TTTCCTGTTTAGAAAGTTCTGCTCCTTCATAAGGACCTTGAAGTACTAGGAGGAAAGGTGCTTTGTGTGTGGAGTTTTCCATGAAGTGCA
GTCCCAACTAAAAGGCTGCGTTAAAGGCTAGAGTAGTGCAGTGGCGTGATCTCAGCTCACTCCAGCCTCTGCCTCCCGGGCTCAAGTGAC
CCACCTGCCTCAGCCTCCCAAGTAGCTGGGACAACAGATGTGAGCCACCACACCCAGATTCACTGCGTGCTGTCCTCACTTGTTCTACAA
TGAGTGCCAAATCTGCTATCAGCAAGGAAATTTTTGCACCTCTTGATGAAAGGATGCTGGGAGCTGTCCAAGTCAAGAGGAGGACAAAGA
AAAAGATTCCTTTCTTGGCAACTGGAGGTCAAGGCGAATATTTAACTTATATCTGCCTGTCAGGAGAAAATGTCCACCTTGGTTCTGGTG
ATGGGCAGTCAAAAGATTCTGGGCCCCTTCCTCAAGTGGAAAAGAAGCTCAAGTGTACAGTTGAAGGTTGTGACCGGACATTTGTATGGC
CAGCTCACTTTAAATACCACCTCAAGACTCATCGAAATGACCGCTCCTTCATCTGTCCTGCAGAAGGTTGTGGGAAAAGCTTCTATGTGC
TGCAGAGGCTGAAGGTGCACATGAGGACCCACAATGGAGAGAAGCCCTTTATGTGCCATGAGTCTGGCTGTGGTAAGCAGTTTACTACAG
CTGGAAACCTGAAGAACCACCGGCGCATCCACACAGGAGAGAAACCTTTCCTTTGTGAAGCCCAAGGATGTGGCCGTTCCTTTGCTGAGT
ATTCTAGCCTCCGAAAACATCTGGTGGTTCACTCAGGAGAGAAGCCTCATCAGTGCCAAGTCTGTGGGAAGACCTTCTCTCAGAGTGGAA
GCAGGAATGTGCATATGAGAAAGCATCACCTGCAGCTGGGAGCAGCTGGGAGTCAAGAGCAGGAGCAAACTGCTGAGCCACTAATGGGCA
GTAGTTTGCTTGAAGAGGCTTCAGTACCCAGTAAAAACCTGGTGTCTATGAATTCCCAGCCCAGCCTTGGTGGAGAGTCCTTGAACCTAC
CAAATACCAATTCTATCCTGGGAGTTGATGATGAGGTGCTTGCTGAAGGATCCCCACGTTCCCTGTCTTCAGTGCCTGATGTGACACATC
ACCTGGTGACCATGCAGTCAGGGAGGCAATCATATGAAGTTTCTGTCTTAACTGCAGTAAATCCACAAGAGTTACTAAACCAAGGAGATT

>87911_87911_8_STXBP6-ZNF410_STXBP6_chr14_25443870_ENST00000550887_ZNF410_chr14_74370662_ENST00000540593_length(amino acids)=345AA_BP=60
MRAVLTCSTMSAKSAISKEIFAPLDERMLGAVQVKRRTKKKIPFLATGGQGEYLTYICLSGENVHLGSGDGQSKDSGPLPQVEKKLKCTV
EGCDRTFVWPAHFKYHLKTHRNDRSFICPAEGCGKSFYVLQRLKVHMRTHNGEKPFMCHESGCGKQFTTAGNLKNHRRIHTGEKPFLCEA
QGCGRSFAEYSSLRKHLVVHSGEKPHQCQVCGKTFSQSGSRNVHMRKHHLQLGAAGSQEQEQTAEPLMGSSLLEEASVPSKNLVSMNSQP

--------------------------------------------------------------
>87911_87911_9_STXBP6-ZNF410_STXBP6_chr14_25443871_ENST00000323944_ZNF410_chr14_74370663_ENST00000324593_length(transcript)=2059nt_BP=606nt
GAGGCCTGGGGCGGGTCGCGGGTCCCGGCCCCCAGCCCCCAGCCCCTAGCCGCTGCTCTTTGCCCCGGGCCAGGGCGCTCGGGCTCGCCC
ACGGCGGCACTGAGCATGCTCAGAGGCGGCCGCGCGGGCAGGTTTGCTTCGCAGGCGCTCGCACTCGGCGGCGGGCGGGCGCGCGGCTGC
AGCTGGAGCTCCAGCGCCCGGAGTTGGAGTTGCCGGGAGTTTCCCCCCAACCCCTCCCTTTTCGCGCGCGGCAGCAGGAGCCGGCGCGGG
AGCCGCGAGCGGCGGCGAGCCAGCACCCGGGCCGGCTAAGCCTTGTCCGGAGCCCGGAGCCCCGCGCGGGGCAGCCCCCCGGGGAGGAGC
CTCGTGCTCTGGGACGCGTGCCGCGCACTGGCACGGCAGGGGCGCGAGCCAGGCTGCACGATTCACTGCGTGCTGTCCTCACTTGTTCTA
CAATGAGTGCCAAATCTGCTATCAGCAAGGAAATTTTTGCACCTCTTGATGAAAGGATGCTGGGAGCTGTCCAAGTCAAGAGGAGGACAA
AGAAAAAGATTCCTTTCTTGGCAACTGGAGGTCAAGGCGAATATTTAACTTATATCTGCCTGTCAGGAGAAAATGTCCACCTTGGTTCTG
GTGATGGGCAGTCAAAAGATTCTGGGCCCCTTCCTCAAGTGGAAAAGAAGCTCAAGTGTACAGTTGAAGGTTGTGACCGGACATTTGTAT
GGCCAGCTCACTTTAAATACCACCTCAAGACTCATCGAAATGACCGCTCCTTCATCTGTCCTGCAGAAGGTTGTGGGAAAAGCTTCTATG
TGCTGCAGAGGCTGAAGGTGCACATGAGGACCCACAATGGAGAGAAGCCCTTTATGTGCCATGAGTCTGGCTGTGGTAAGCAGTTTACTA
CAGCTGGAAACCTGAAGAACCACCGGCGCATCCACACAGGAGAGAAACCTTTCCTTTGTGAAGCCCAAGGATGTGGCCGTTCCTTTGCTG
AGTATTCTAGCCTCCGAAAACATCTGGTGGTTCACTCAGGAGAGAAGCCTCATCAGTGCCAAGTCTGTGGGAAGACCTTCTCTCAGAGTG
GAAGCAGGAATGTGCATATGAGAAAGCATCACCTGCAGCTGGGAGCAGCTGGGAGTCAAGAGCAGGAGCAAACTGAGGTGCTTGCTGAAG
GATCCCCACGTTCCCTGTCTTCAGTGCCTGATGTGACACATCACCTGGTGACCATGCAGTCAGGGAGGCAATCATATGAAGTTTCTGTCT
TAACTGCAGTAAATCCACAAGAGTTACTAAACCAAGGAGATTTAACTGAAAGACGGACATGAGCGTGGGTGCTGACTCCTGGAAGAGCAA
CTCTATCTGATCTCAAAATGCGTATACTGGGAACAGGATGCCTTAGCCCACAACAGAACCAGAATGAATCTTTGAAGGCACAAGACTCTG
CTTTTGCCACTCTTCCTCTTTCCTGGTATAGAAGATGGATGTAGGAGAGCTTCTTTTCTAACTACCATCTGATCAGACAAGGAATGAAGC
AATGACTGTGGGCTGGGAAACTGTACCTACCTCTCTTCCCACTGCAAATTTCTGGGATAGACCAAAAGTGAATTTGATTATGTGTTGGCT
GAAGTTCTTCATTCTGACTGTTGAGGGGAGGTTTTCCTTTGAAGAGTTTTCATCCCAGACTCAGCTGTCTTTTCACATGGATGAAATAAT
TCCTGCTACCAACAACAGAGCTTCACCAGGAAGTTGAGTTTTCAAGATGCCTTGTTGCTTTGAAGAAGGGAGTGATGTCAATTCTCTTGT
TACATTCTCCCTTTAGCAACCTGAGTAAGAGACTCTCTGCCACTGGGCTGCAAAAAAATAAATTACTTGAATCTCCCCTTGGCCCAGGCT
GAGGTACTATCTTGTCCTATACACTTCTACTTGGTCACTTTGCTTTCTTCGTTAATGGAACATACAGTAGCATGTTAAGAGGGATTTCAT

>87911_87911_9_STXBP6-ZNF410_STXBP6_chr14_25443871_ENST00000323944_ZNF410_chr14_74370663_ENST00000324593_length(amino acids)=438AA_BP=200
MGRVAGPGPQPPAPSRCSLPRARALGLAHGGTEHAQRRPRGQVCFAGARTRRRAGARLQLELQRPELELPGVSPQPLPFRARQQEPAREP
RAAASQHPGRLSLVRSPEPRAGQPPGEEPRALGRVPRTGTAGARARLHDSLRAVLTCSTMSAKSAISKEIFAPLDERMLGAVQVKRRTKK
KIPFLATGGQGEYLTYICLSGENVHLGSGDGQSKDSGPLPQVEKKLKCTVEGCDRTFVWPAHFKYHLKTHRNDRSFICPAEGCGKSFYVL
QRLKVHMRTHNGEKPFMCHESGCGKQFTTAGNLKNHRRIHTGEKPFLCEAQGCGRSFAEYSSLRKHLVVHSGEKPHQCQVCGKTFSQSGS

--------------------------------------------------------------
>87911_87911_10_STXBP6-ZNF410_STXBP6_chr14_25443871_ENST00000323944_ZNF410_chr14_74370663_ENST00000540593_length(transcript)=1519nt_BP=606nt
GAGGCCTGGGGCGGGTCGCGGGTCCCGGCCCCCAGCCCCCAGCCCCTAGCCGCTGCTCTTTGCCCCGGGCCAGGGCGCTCGGGCTCGCCC
ACGGCGGCACTGAGCATGCTCAGAGGCGGCCGCGCGGGCAGGTTTGCTTCGCAGGCGCTCGCACTCGGCGGCGGGCGGGCGCGCGGCTGC
AGCTGGAGCTCCAGCGCCCGGAGTTGGAGTTGCCGGGAGTTTCCCCCCAACCCCTCCCTTTTCGCGCGCGGCAGCAGGAGCCGGCGCGGG
AGCCGCGAGCGGCGGCGAGCCAGCACCCGGGCCGGCTAAGCCTTGTCCGGAGCCCGGAGCCCCGCGCGGGGCAGCCCCCCGGGGAGGAGC
CTCGTGCTCTGGGACGCGTGCCGCGCACTGGCACGGCAGGGGCGCGAGCCAGGCTGCACGATTCACTGCGTGCTGTCCTCACTTGTTCTA
CAATGAGTGCCAAATCTGCTATCAGCAAGGAAATTTTTGCACCTCTTGATGAAAGGATGCTGGGAGCTGTCCAAGTCAAGAGGAGGACAA
AGAAAAAGATTCCTTTCTTGGCAACTGGAGGTCAAGGCGAATATTTAACTTATATCTGCCTGTCAGGAGAAAATGTCCACCTTGGTTCTG
GTGATGGGCAGTCAAAAGATTCTGGGCCCCTTCCTCAAGTGGAAAAGAAGCTCAAGTGTACAGTTGAAGGTTGTGACCGGACATTTGTAT
GGCCAGCTCACTTTAAATACCACCTCAAGACTCATCGAAATGACCGCTCCTTCATCTGTCCTGCAGAAGGTTGTGGGAAAAGCTTCTATG
TGCTGCAGAGGCTGAAGGTGCACATGAGGACCCACAATGGAGAGAAGCCCTTTATGTGCCATGAGTCTGGCTGTGGTAAGCAGTTTACTA
CAGCTGGAAACCTGAAGAACCACCGGCGCATCCACACAGGAGAGAAACCTTTCCTTTGTGAAGCCCAAGGATGTGGCCGTTCCTTTGCTG
AGTATTCTAGCCTCCGAAAACATCTGGTGGTTCACTCAGGAGAGAAGCCTCATCAGTGCCAAGTCTGTGGGAAGACCTTCTCTCAGAGTG
GAAGCAGGAATGTGCATATGAGAAAGCATCACCTGCAGCTGGGAGCAGCTGGGAGTCAAGAGCAGGAGCAAACTGCTGAGCCACTAATGG
GCAGTAGTTTGCTTGAAGAGGCTTCAGTACCCAGTAAAAACCTGGTGTCTATGAATTCCCAGCCCAGCCTTGGTGGAGAGTCCTTGAACC
TACCAAATACCAATTCTATCCTGGGAGTTGATGATGAGGTGCTTGCTGAAGGATCCCCACGTTCCCTGTCTTCAGTGCCTGATGTGACAC
ATCACCTGGTGACCATGCAGTCAGGGAGGCAATCATATGAAGTTTCTGTCTTAACTGCAGTAAATCCACAAGAGTTACTAAACCAAGGAG

>87911_87911_10_STXBP6-ZNF410_STXBP6_chr14_25443871_ENST00000323944_ZNF410_chr14_74370663_ENST00000540593_length(amino acids)=485AA_BP=200
MGRVAGPGPQPPAPSRCSLPRARALGLAHGGTEHAQRRPRGQVCFAGARTRRRAGARLQLELQRPELELPGVSPQPLPFRARQQEPAREP
RAAASQHPGRLSLVRSPEPRAGQPPGEEPRALGRVPRTGTAGARARLHDSLRAVLTCSTMSAKSAISKEIFAPLDERMLGAVQVKRRTKK
KIPFLATGGQGEYLTYICLSGENVHLGSGDGQSKDSGPLPQVEKKLKCTVEGCDRTFVWPAHFKYHLKTHRNDRSFICPAEGCGKSFYVL
QRLKVHMRTHNGEKPFMCHESGCGKQFTTAGNLKNHRRIHTGEKPFLCEAQGCGRSFAEYSSLRKHLVVHSGEKPHQCQVCGKTFSQSGS
RNVHMRKHHLQLGAAGSQEQEQTAEPLMGSSLLEEASVPSKNLVSMNSQPSLGGESLNLPNTNSILGVDDEVLAEGSPRSLSSVPDVTHH

--------------------------------------------------------------
>87911_87911_11_STXBP6-ZNF410_STXBP6_chr14_25443871_ENST00000358326_ZNF410_chr14_74370663_ENST00000324593_length(transcript)=1660nt_BP=207nt
GGGCGCGAGCCAGGCTGCACGATTCACTGCGTGCTGTCCTCACTTGTTCTACAATGAGTGCCAAATCTGCTATCAGCAAGGAAATTTTTG
CACCTCTTGATGAAAGGATGCTGGGAGCTGTCCAAGTCAAGAGGAGGACAAAGAAAAAGATTCCTTTCTTGGCAACTGGAGGTCAAGGCG
AATATTTAACTTATATCTGCCTGTCAGGAGAAAATGTCCACCTTGGTTCTGGTGATGGGCAGTCAAAAGATTCTGGGCCCCTTCCTCAAG
TGGAAAAGAAGCTCAAGTGTACAGTTGAAGGTTGTGACCGGACATTTGTATGGCCAGCTCACTTTAAATACCACCTCAAGACTCATCGAA
ATGACCGCTCCTTCATCTGTCCTGCAGAAGGTTGTGGGAAAAGCTTCTATGTGCTGCAGAGGCTGAAGGTGCACATGAGGACCCACAATG
GAGAGAAGCCCTTTATGTGCCATGAGTCTGGCTGTGGTAAGCAGTTTACTACAGCTGGAAACCTGAAGAACCACCGGCGCATCCACACAG
GAGAGAAACCTTTCCTTTGTGAAGCCCAAGGATGTGGCCGTTCCTTTGCTGAGTATTCTAGCCTCCGAAAACATCTGGTGGTTCACTCAG
GAGAGAAGCCTCATCAGTGCCAAGTCTGTGGGAAGACCTTCTCTCAGAGTGGAAGCAGGAATGTGCATATGAGAAAGCATCACCTGCAGC
TGGGAGCAGCTGGGAGTCAAGAGCAGGAGCAAACTGAGGTGCTTGCTGAAGGATCCCCACGTTCCCTGTCTTCAGTGCCTGATGTGACAC
ATCACCTGGTGACCATGCAGTCAGGGAGGCAATCATATGAAGTTTCTGTCTTAACTGCAGTAAATCCACAAGAGTTACTAAACCAAGGAG
ATTTAACTGAAAGACGGACATGAGCGTGGGTGCTGACTCCTGGAAGAGCAACTCTATCTGATCTCAAAATGCGTATACTGGGAACAGGAT
GCCTTAGCCCACAACAGAACCAGAATGAATCTTTGAAGGCACAAGACTCTGCTTTTGCCACTCTTCCTCTTTCCTGGTATAGAAGATGGA
TGTAGGAGAGCTTCTTTTCTAACTACCATCTGATCAGACAAGGAATGAAGCAATGACTGTGGGCTGGGAAACTGTACCTACCTCTCTTCC
CACTGCAAATTTCTGGGATAGACCAAAAGTGAATTTGATTATGTGTTGGCTGAAGTTCTTCATTCTGACTGTTGAGGGGAGGTTTTCCTT
TGAAGAGTTTTCATCCCAGACTCAGCTGTCTTTTCACATGGATGAAATAATTCCTGCTACCAACAACAGAGCTTCACCAGGAAGTTGAGT
TTTCAAGATGCCTTGTTGCTTTGAAGAAGGGAGTGATGTCAATTCTCTTGTTACATTCTCCCTTTAGCAACCTGAGTAAGAGACTCTCTG
CCACTGGGCTGCAAAAAAATAAATTACTTGAATCTCCCCTTGGCCCAGGCTGAGGTACTATCTTGTCCTATACACTTCTACTTGGTCACT
TTGCTTTCTTCGTTAATGGAACATACAGTAGCATGTTAAGAGGGATTTCATGTTTTTGTTTTTTTAAAGTTAAAAATTACATGATGCAGA

>87911_87911_11_STXBP6-ZNF410_STXBP6_chr14_25443871_ENST00000358326_ZNF410_chr14_74370663_ENST00000324593_length(amino acids)=302AA_BP=64
MHDSLRAVLTCSTMSAKSAISKEIFAPLDERMLGAVQVKRRTKKKIPFLATGGQGEYLTYICLSGENVHLGSGDGQSKDSGPLPQVEKKL
KCTVEGCDRTFVWPAHFKYHLKTHRNDRSFICPAEGCGKSFYVLQRLKVHMRTHNGEKPFMCHESGCGKQFTTAGNLKNHRRIHTGEKPF
LCEAQGCGRSFAEYSSLRKHLVVHSGEKPHQCQVCGKTFSQSGSRNVHMRKHHLQLGAAGSQEQEQTEVLAEGSPRSLSSVPDVTHHLVT

--------------------------------------------------------------
>87911_87911_12_STXBP6-ZNF410_STXBP6_chr14_25443871_ENST00000358326_ZNF410_chr14_74370663_ENST00000540593_length(transcript)=1120nt_BP=207nt
GGGCGCGAGCCAGGCTGCACGATTCACTGCGTGCTGTCCTCACTTGTTCTACAATGAGTGCCAAATCTGCTATCAGCAAGGAAATTTTTG
CACCTCTTGATGAAAGGATGCTGGGAGCTGTCCAAGTCAAGAGGAGGACAAAGAAAAAGATTCCTTTCTTGGCAACTGGAGGTCAAGGCG
AATATTTAACTTATATCTGCCTGTCAGGAGAAAATGTCCACCTTGGTTCTGGTGATGGGCAGTCAAAAGATTCTGGGCCCCTTCCTCAAG
TGGAAAAGAAGCTCAAGTGTACAGTTGAAGGTTGTGACCGGACATTTGTATGGCCAGCTCACTTTAAATACCACCTCAAGACTCATCGAA
ATGACCGCTCCTTCATCTGTCCTGCAGAAGGTTGTGGGAAAAGCTTCTATGTGCTGCAGAGGCTGAAGGTGCACATGAGGACCCACAATG
GAGAGAAGCCCTTTATGTGCCATGAGTCTGGCTGTGGTAAGCAGTTTACTACAGCTGGAAACCTGAAGAACCACCGGCGCATCCACACAG
GAGAGAAACCTTTCCTTTGTGAAGCCCAAGGATGTGGCCGTTCCTTTGCTGAGTATTCTAGCCTCCGAAAACATCTGGTGGTTCACTCAG
GAGAGAAGCCTCATCAGTGCCAAGTCTGTGGGAAGACCTTCTCTCAGAGTGGAAGCAGGAATGTGCATATGAGAAAGCATCACCTGCAGC
TGGGAGCAGCTGGGAGTCAAGAGCAGGAGCAAACTGCTGAGCCACTAATGGGCAGTAGTTTGCTTGAAGAGGCTTCAGTACCCAGTAAAA
ACCTGGTGTCTATGAATTCCCAGCCCAGCCTTGGTGGAGAGTCCTTGAACCTACCAAATACCAATTCTATCCTGGGAGTTGATGATGAGG
TGCTTGCTGAAGGATCCCCACGTTCCCTGTCTTCAGTGCCTGATGTGACACATCACCTGGTGACCATGCAGTCAGGGAGGCAATCATATG
AAGTTTCTGTCTTAACTGCAGTAAATCCACAAGAGTTACTAAACCAAGGAGATTTAACTGAAAGACGGACATGAGCGTGGGTGCTGACTC

>87911_87911_12_STXBP6-ZNF410_STXBP6_chr14_25443871_ENST00000358326_ZNF410_chr14_74370663_ENST00000540593_length(amino acids)=349AA_BP=64
MHDSLRAVLTCSTMSAKSAISKEIFAPLDERMLGAVQVKRRTKKKIPFLATGGQGEYLTYICLSGENVHLGSGDGQSKDSGPLPQVEKKL
KCTVEGCDRTFVWPAHFKYHLKTHRNDRSFICPAEGCGKSFYVLQRLKVHMRTHNGEKPFMCHESGCGKQFTTAGNLKNHRRIHTGEKPF
LCEAQGCGRSFAEYSSLRKHLVVHSGEKPHQCQVCGKTFSQSGSRNVHMRKHHLQLGAAGSQEQEQTAEPLMGSSLLEEASVPSKNLVSM

--------------------------------------------------------------
>87911_87911_13_STXBP6-ZNF410_STXBP6_chr14_25443871_ENST00000546511_ZNF410_chr14_74370663_ENST00000324593_length(transcript)=1680nt_BP=227nt
ATTACGCTTCCCTAGGGACTGGGTGGGAGAGAATAGGATCGATTCACTGCGTGCTGTCCTCACTTGTTCTACAATGAGTGCCAAATCTGC
TATCAGCAAGGAAATTTTTGCACCTCTTGATGAAAGGATGCTGGGAGCTGTCCAAGTCAAGAGGAGGACAAAGAAAAAGATTCCTTTCTT
GGCAACTGGAGGTCAAGGCGAATATTTAACTTATATCTGCCTGTCAGGAGAAAATGTCCACCTTGGTTCTGGTGATGGGCAGTCAAAAGA
TTCTGGGCCCCTTCCTCAAGTGGAAAAGAAGCTCAAGTGTACAGTTGAAGGTTGTGACCGGACATTTGTATGGCCAGCTCACTTTAAATA
CCACCTCAAGACTCATCGAAATGACCGCTCCTTCATCTGTCCTGCAGAAGGTTGTGGGAAAAGCTTCTATGTGCTGCAGAGGCTGAAGGT
GCACATGAGGACCCACAATGGAGAGAAGCCCTTTATGTGCCATGAGTCTGGCTGTGGTAAGCAGTTTACTACAGCTGGAAACCTGAAGAA
CCACCGGCGCATCCACACAGGAGAGAAACCTTTCCTTTGTGAAGCCCAAGGATGTGGCCGTTCCTTTGCTGAGTATTCTAGCCTCCGAAA
ACATCTGGTGGTTCACTCAGGAGAGAAGCCTCATCAGTGCCAAGTCTGTGGGAAGACCTTCTCTCAGAGTGGAAGCAGGAATGTGCATAT
GAGAAAGCATCACCTGCAGCTGGGAGCAGCTGGGAGTCAAGAGCAGGAGCAAACTGAGGTGCTTGCTGAAGGATCCCCACGTTCCCTGTC
TTCAGTGCCTGATGTGACACATCACCTGGTGACCATGCAGTCAGGGAGGCAATCATATGAAGTTTCTGTCTTAACTGCAGTAAATCCACA
AGAGTTACTAAACCAAGGAGATTTAACTGAAAGACGGACATGAGCGTGGGTGCTGACTCCTGGAAGAGCAACTCTATCTGATCTCAAAAT
GCGTATACTGGGAACAGGATGCCTTAGCCCACAACAGAACCAGAATGAATCTTTGAAGGCACAAGACTCTGCTTTTGCCACTCTTCCTCT
TTCCTGGTATAGAAGATGGATGTAGGAGAGCTTCTTTTCTAACTACCATCTGATCAGACAAGGAATGAAGCAATGACTGTGGGCTGGGAA
ACTGTACCTACCTCTCTTCCCACTGCAAATTTCTGGGATAGACCAAAAGTGAATTTGATTATGTGTTGGCTGAAGTTCTTCATTCTGACT
GTTGAGGGGAGGTTTTCCTTTGAAGAGTTTTCATCCCAGACTCAGCTGTCTTTTCACATGGATGAAATAATTCCTGCTACCAACAACAGA
GCTTCACCAGGAAGTTGAGTTTTCAAGATGCCTTGTTGCTTTGAAGAAGGGAGTGATGTCAATTCTCTTGTTACATTCTCCCTTTAGCAA
CCTGAGTAAGAGACTCTCTGCCACTGGGCTGCAAAAAAATAAATTACTTGAATCTCCCCTTGGCCCAGGCTGAGGTACTATCTTGTCCTA
TACACTTCTACTTGGTCACTTTGCTTTCTTCGTTAATGGAACATACAGTAGCATGTTAAGAGGGATTTCATGTTTTTGTTTTTTTAAAGT

>87911_87911_13_STXBP6-ZNF410_STXBP6_chr14_25443871_ENST00000546511_ZNF410_chr14_74370663_ENST00000324593_length(amino acids)=298AA_BP=60
MRAVLTCSTMSAKSAISKEIFAPLDERMLGAVQVKRRTKKKIPFLATGGQGEYLTYICLSGENVHLGSGDGQSKDSGPLPQVEKKLKCTV
EGCDRTFVWPAHFKYHLKTHRNDRSFICPAEGCGKSFYVLQRLKVHMRTHNGEKPFMCHESGCGKQFTTAGNLKNHRRIHTGEKPFLCEA
QGCGRSFAEYSSLRKHLVVHSGEKPHQCQVCGKTFSQSGSRNVHMRKHHLQLGAAGSQEQEQTEVLAEGSPRSLSSVPDVTHHLVTMQSG

--------------------------------------------------------------
>87911_87911_14_STXBP6-ZNF410_STXBP6_chr14_25443871_ENST00000546511_ZNF410_chr14_74370663_ENST00000540593_length(transcript)=1140nt_BP=227nt
ATTACGCTTCCCTAGGGACTGGGTGGGAGAGAATAGGATCGATTCACTGCGTGCTGTCCTCACTTGTTCTACAATGAGTGCCAAATCTGC
TATCAGCAAGGAAATTTTTGCACCTCTTGATGAAAGGATGCTGGGAGCTGTCCAAGTCAAGAGGAGGACAAAGAAAAAGATTCCTTTCTT
GGCAACTGGAGGTCAAGGCGAATATTTAACTTATATCTGCCTGTCAGGAGAAAATGTCCACCTTGGTTCTGGTGATGGGCAGTCAAAAGA
TTCTGGGCCCCTTCCTCAAGTGGAAAAGAAGCTCAAGTGTACAGTTGAAGGTTGTGACCGGACATTTGTATGGCCAGCTCACTTTAAATA
CCACCTCAAGACTCATCGAAATGACCGCTCCTTCATCTGTCCTGCAGAAGGTTGTGGGAAAAGCTTCTATGTGCTGCAGAGGCTGAAGGT
GCACATGAGGACCCACAATGGAGAGAAGCCCTTTATGTGCCATGAGTCTGGCTGTGGTAAGCAGTTTACTACAGCTGGAAACCTGAAGAA
CCACCGGCGCATCCACACAGGAGAGAAACCTTTCCTTTGTGAAGCCCAAGGATGTGGCCGTTCCTTTGCTGAGTATTCTAGCCTCCGAAA
ACATCTGGTGGTTCACTCAGGAGAGAAGCCTCATCAGTGCCAAGTCTGTGGGAAGACCTTCTCTCAGAGTGGAAGCAGGAATGTGCATAT
GAGAAAGCATCACCTGCAGCTGGGAGCAGCTGGGAGTCAAGAGCAGGAGCAAACTGCTGAGCCACTAATGGGCAGTAGTTTGCTTGAAGA
GGCTTCAGTACCCAGTAAAAACCTGGTGTCTATGAATTCCCAGCCCAGCCTTGGTGGAGAGTCCTTGAACCTACCAAATACCAATTCTAT
CCTGGGAGTTGATGATGAGGTGCTTGCTGAAGGATCCCCACGTTCCCTGTCTTCAGTGCCTGATGTGACACATCACCTGGTGACCATGCA
GTCAGGGAGGCAATCATATGAAGTTTCTGTCTTAACTGCAGTAAATCCACAAGAGTTACTAAACCAAGGAGATTTAACTGAAAGACGGAC

>87911_87911_14_STXBP6-ZNF410_STXBP6_chr14_25443871_ENST00000546511_ZNF410_chr14_74370663_ENST00000540593_length(amino acids)=345AA_BP=60
MRAVLTCSTMSAKSAISKEIFAPLDERMLGAVQVKRRTKKKIPFLATGGQGEYLTYICLSGENVHLGSGDGQSKDSGPLPQVEKKLKCTV
EGCDRTFVWPAHFKYHLKTHRNDRSFICPAEGCGKSFYVLQRLKVHMRTHNGEKPFMCHESGCGKQFTTAGNLKNHRRIHTGEKPFLCEA
QGCGRSFAEYSSLRKHLVVHSGEKPHQCQVCGKTFSQSGSRNVHMRKHHLQLGAAGSQEQEQTAEPLMGSSLLEEASVPSKNLVSMNSQP

--------------------------------------------------------------
>87911_87911_15_STXBP6-ZNF410_STXBP6_chr14_25443871_ENST00000550887_ZNF410_chr14_74370663_ENST00000324593_length(transcript)=1876nt_BP=423nt
TTTCCTGTTTAGAAAGTTCTGCTCCTTCATAAGGACCTTGAAGTACTAGGAGGAAAGGTGCTTTGTGTGTGGAGTTTTCCATGAAGTGCA
GTCCCAACTAAAAGGCTGCGTTAAAGGCTAGAGTAGTGCAGTGGCGTGATCTCAGCTCACTCCAGCCTCTGCCTCCCGGGCTCAAGTGAC
CCACCTGCCTCAGCCTCCCAAGTAGCTGGGACAACAGATGTGAGCCACCACACCCAGATTCACTGCGTGCTGTCCTCACTTGTTCTACAA
TGAGTGCCAAATCTGCTATCAGCAAGGAAATTTTTGCACCTCTTGATGAAAGGATGCTGGGAGCTGTCCAAGTCAAGAGGAGGACAAAGA
AAAAGATTCCTTTCTTGGCAACTGGAGGTCAAGGCGAATATTTAACTTATATCTGCCTGTCAGGAGAAAATGTCCACCTTGGTTCTGGTG
ATGGGCAGTCAAAAGATTCTGGGCCCCTTCCTCAAGTGGAAAAGAAGCTCAAGTGTACAGTTGAAGGTTGTGACCGGACATTTGTATGGC
CAGCTCACTTTAAATACCACCTCAAGACTCATCGAAATGACCGCTCCTTCATCTGTCCTGCAGAAGGTTGTGGGAAAAGCTTCTATGTGC
TGCAGAGGCTGAAGGTGCACATGAGGACCCACAATGGAGAGAAGCCCTTTATGTGCCATGAGTCTGGCTGTGGTAAGCAGTTTACTACAG
CTGGAAACCTGAAGAACCACCGGCGCATCCACACAGGAGAGAAACCTTTCCTTTGTGAAGCCCAAGGATGTGGCCGTTCCTTTGCTGAGT
ATTCTAGCCTCCGAAAACATCTGGTGGTTCACTCAGGAGAGAAGCCTCATCAGTGCCAAGTCTGTGGGAAGACCTTCTCTCAGAGTGGAA
GCAGGAATGTGCATATGAGAAAGCATCACCTGCAGCTGGGAGCAGCTGGGAGTCAAGAGCAGGAGCAAACTGAGGTGCTTGCTGAAGGAT
CCCCACGTTCCCTGTCTTCAGTGCCTGATGTGACACATCACCTGGTGACCATGCAGTCAGGGAGGCAATCATATGAAGTTTCTGTCTTAA
CTGCAGTAAATCCACAAGAGTTACTAAACCAAGGAGATTTAACTGAAAGACGGACATGAGCGTGGGTGCTGACTCCTGGAAGAGCAACTC
TATCTGATCTCAAAATGCGTATACTGGGAACAGGATGCCTTAGCCCACAACAGAACCAGAATGAATCTTTGAAGGCACAAGACTCTGCTT
TTGCCACTCTTCCTCTTTCCTGGTATAGAAGATGGATGTAGGAGAGCTTCTTTTCTAACTACCATCTGATCAGACAAGGAATGAAGCAAT
GACTGTGGGCTGGGAAACTGTACCTACCTCTCTTCCCACTGCAAATTTCTGGGATAGACCAAAAGTGAATTTGATTATGTGTTGGCTGAA
GTTCTTCATTCTGACTGTTGAGGGGAGGTTTTCCTTTGAAGAGTTTTCATCCCAGACTCAGCTGTCTTTTCACATGGATGAAATAATTCC
TGCTACCAACAACAGAGCTTCACCAGGAAGTTGAGTTTTCAAGATGCCTTGTTGCTTTGAAGAAGGGAGTGATGTCAATTCTCTTGTTAC
ATTCTCCCTTTAGCAACCTGAGTAAGAGACTCTCTGCCACTGGGCTGCAAAAAAATAAATTACTTGAATCTCCCCTTGGCCCAGGCTGAG
GTACTATCTTGTCCTATACACTTCTACTTGGTCACTTTGCTTTCTTCGTTAATGGAACATACAGTAGCATGTTAAGAGGGATTTCATGTT

>87911_87911_15_STXBP6-ZNF410_STXBP6_chr14_25443871_ENST00000550887_ZNF410_chr14_74370663_ENST00000324593_length(amino acids)=298AA_BP=60
MRAVLTCSTMSAKSAISKEIFAPLDERMLGAVQVKRRTKKKIPFLATGGQGEYLTYICLSGENVHLGSGDGQSKDSGPLPQVEKKLKCTV
EGCDRTFVWPAHFKYHLKTHRNDRSFICPAEGCGKSFYVLQRLKVHMRTHNGEKPFMCHESGCGKQFTTAGNLKNHRRIHTGEKPFLCEA
QGCGRSFAEYSSLRKHLVVHSGEKPHQCQVCGKTFSQSGSRNVHMRKHHLQLGAAGSQEQEQTEVLAEGSPRSLSSVPDVTHHLVTMQSG

--------------------------------------------------------------
>87911_87911_16_STXBP6-ZNF410_STXBP6_chr14_25443871_ENST00000550887_ZNF410_chr14_74370663_ENST00000540593_length(transcript)=1336nt_BP=423nt
TTTCCTGTTTAGAAAGTTCTGCTCCTTCATAAGGACCTTGAAGTACTAGGAGGAAAGGTGCTTTGTGTGTGGAGTTTTCCATGAAGTGCA
GTCCCAACTAAAAGGCTGCGTTAAAGGCTAGAGTAGTGCAGTGGCGTGATCTCAGCTCACTCCAGCCTCTGCCTCCCGGGCTCAAGTGAC
CCACCTGCCTCAGCCTCCCAAGTAGCTGGGACAACAGATGTGAGCCACCACACCCAGATTCACTGCGTGCTGTCCTCACTTGTTCTACAA
TGAGTGCCAAATCTGCTATCAGCAAGGAAATTTTTGCACCTCTTGATGAAAGGATGCTGGGAGCTGTCCAAGTCAAGAGGAGGACAAAGA
AAAAGATTCCTTTCTTGGCAACTGGAGGTCAAGGCGAATATTTAACTTATATCTGCCTGTCAGGAGAAAATGTCCACCTTGGTTCTGGTG
ATGGGCAGTCAAAAGATTCTGGGCCCCTTCCTCAAGTGGAAAAGAAGCTCAAGTGTACAGTTGAAGGTTGTGACCGGACATTTGTATGGC
CAGCTCACTTTAAATACCACCTCAAGACTCATCGAAATGACCGCTCCTTCATCTGTCCTGCAGAAGGTTGTGGGAAAAGCTTCTATGTGC
TGCAGAGGCTGAAGGTGCACATGAGGACCCACAATGGAGAGAAGCCCTTTATGTGCCATGAGTCTGGCTGTGGTAAGCAGTTTACTACAG
CTGGAAACCTGAAGAACCACCGGCGCATCCACACAGGAGAGAAACCTTTCCTTTGTGAAGCCCAAGGATGTGGCCGTTCCTTTGCTGAGT
ATTCTAGCCTCCGAAAACATCTGGTGGTTCACTCAGGAGAGAAGCCTCATCAGTGCCAAGTCTGTGGGAAGACCTTCTCTCAGAGTGGAA
GCAGGAATGTGCATATGAGAAAGCATCACCTGCAGCTGGGAGCAGCTGGGAGTCAAGAGCAGGAGCAAACTGCTGAGCCACTAATGGGCA
GTAGTTTGCTTGAAGAGGCTTCAGTACCCAGTAAAAACCTGGTGTCTATGAATTCCCAGCCCAGCCTTGGTGGAGAGTCCTTGAACCTAC
CAAATACCAATTCTATCCTGGGAGTTGATGATGAGGTGCTTGCTGAAGGATCCCCACGTTCCCTGTCTTCAGTGCCTGATGTGACACATC
ACCTGGTGACCATGCAGTCAGGGAGGCAATCATATGAAGTTTCTGTCTTAACTGCAGTAAATCCACAAGAGTTACTAAACCAAGGAGATT

>87911_87911_16_STXBP6-ZNF410_STXBP6_chr14_25443871_ENST00000550887_ZNF410_chr14_74370663_ENST00000540593_length(amino acids)=345AA_BP=60
MRAVLTCSTMSAKSAISKEIFAPLDERMLGAVQVKRRTKKKIPFLATGGQGEYLTYICLSGENVHLGSGDGQSKDSGPLPQVEKKLKCTV
EGCDRTFVWPAHFKYHLKTHRNDRSFICPAEGCGKSFYVLQRLKVHMRTHNGEKPFMCHESGCGKQFTTAGNLKNHRRIHTGEKPFLCEA
QGCGRSFAEYSSLRKHLVVHSGEKPHQCQVCGKTFSQSGSRNVHMRKHHLQLGAAGSQEQEQTAEPLMGSSLLEEASVPSKNLVSMNSQP

--------------------------------------------------------------

Top

Fusion Gene PPI Analysis for STXBP6-ZNF410


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


Top

Related Drugs for STXBP6-ZNF410


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

Top

Related Diseases for STXBP6-ZNF410


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource