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 | Fusion Gene Summary |
| Fusion Gene ORF analysis |
| Fusion Genomic Features |
| Fusion Protein Features |
| Fusion Gene Sequence |
| Fusion Gene PPI analysis |
| Related Drugs |
| Related Diseases |
Fusion gene:SUDS3-EEA1 (FusionGDB2 ID:87975) |
Fusion Gene Summary for SUDS3-EEA1 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: SUDS3-EEA1 | Fusion gene ID: 87975 | Hgene | Tgene | Gene symbol | SUDS3 | EEA1 | Gene ID | 64426 | 8411 |
| Gene name | SDS3 homolog, SIN3A corepressor complex component | early endosome antigen 1 | |
| Synonyms | SAP45|SDS3 | MST105|MSTP105|ZFYVE2 | |
| Cytomap | 12q24.23 | 12q22 | |
| Type of gene | protein-coding | protein-coding | |
| Description | sin3 histone deacetylase corepressor complex component SDS345 kDa Sin3-associated polypeptidesin3A-associated protein, 45kDasuppressor of defective silencing 3 protein homolog | early endosome antigen 1early endosome antigen 1, 162kDearly endosome-associated proteinendosome-associated protein p162zinc finger FYVE domain-containing protein 2 | |
| Modification date | 20200313 | 20200313 | |
| UniProtAcc | . | Q15075 | |
| Ensembl transtripts involved in fusion gene | ENST00000541280, ENST00000397564, ENST00000543473, | ENST00000322349, ENST00000547833, | |
| Fusion gene scores | * DoF score | 3 X 3 X 2=18 | 27 X 9 X 13=3159 |
| # samples | 3 | 27 | |
| ** MAII score | log2(3/18*10)=0.736965594166206 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | log2(27/3159*10)=-3.54843662469604 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: SUDS3 [Title/Abstract] AND EEA1 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Most frequent breakpoint | SUDS3(118841322)-EEA1(93251261), # samples:1 | ||
| Anticipated loss of major functional domain due to fusion event. | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Hgene | SUDS3 | GO:0016575 | histone deacetylation | 21239494 |
| Fusion gene breakpoints across SUDS3 (5'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
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| Fusion gene breakpoints across EEA1 (3'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
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| Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Source | Disease | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| ChimerDB4 | GBM | TCGA-06-0129-01A | SUDS3 | chr12 | 118841322 | + | EEA1 | chr12 | 93251261 | - |
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Fusion Gene ORF analysis for SUDS3-EEA1 |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| 3UTR-3CDS | ENST00000541280 | ENST00000322349 | SUDS3 | chr12 | 118841322 | + | EEA1 | chr12 | 93251261 | - |
| 3UTR-5UTR | ENST00000541280 | ENST00000547833 | SUDS3 | chr12 | 118841322 | + | EEA1 | chr12 | 93251261 | - |
| 5CDS-5UTR | ENST00000397564 | ENST00000547833 | SUDS3 | chr12 | 118841322 | + | EEA1 | chr12 | 93251261 | - |
| 5CDS-5UTR | ENST00000543473 | ENST00000547833 | SUDS3 | chr12 | 118841322 | + | EEA1 | chr12 | 93251261 | - |
| In-frame | ENST00000397564 | ENST00000322349 | SUDS3 | chr12 | 118841322 | + | EEA1 | chr12 | 93251261 | - |
| In-frame | ENST00000543473 | ENST00000322349 | SUDS3 | chr12 | 118841322 | + | EEA1 | chr12 | 93251261 | - |
| ORFfinder result based on the fusion transcript sequence of in-frame fusion genes. |
| Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | Seq length (transcript) | BP loci (transcript) | Predicted start (transcript) | Predicted stop (transcript) | Seq length (amino acids) |
| ENST00000543473 | SUDS3 | chr12 | 118841322 | + | ENST00000322349 | EEA1 | chr12 | 93251261 | - | 10480 | 1115 | 1128 | 5105 | 1325 |
| ENST00000397564 | SUDS3 | chr12 | 118841322 | + | ENST00000322349 | EEA1 | chr12 | 93251261 | - | 10310 | 945 | 958 | 4935 | 1325 |
| DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated. |
| Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | No-coding score | Coding score |
| ENST00000543473 | ENST00000322349 | SUDS3 | chr12 | 118841322 | + | EEA1 | chr12 | 93251261 | - | 0.000835127 | 0.99916494 |
| ENST00000397564 | ENST00000322349 | SUDS3 | chr12 | 118841322 | + | EEA1 | chr12 | 93251261 | - | 0.000713306 | 0.9992867 |
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Fusion Genomic Features for SUDS3-EEA1 |
| FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints. |
| Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | 1-p | p (fusion gene breakpoint) |
| Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page. |
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| Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page. |
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Fusion Protein Features for SUDS3-EEA1 |
| Four levels of functional features of fusion genes Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr12:118841322/chr12:93251261) - FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels. - How to search 1. Put your fusion gene symbol. 2. Press the tab key until there will be shown the breakpoint information filled. 4. Go down and press 'Search' tab twice. 4. Go down to have the hyperlink of the search result. 5. Click the hyperlink. 6. See the FGviewer result for your fusion gene. |
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| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| . | EEA1 |
| FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}. | FUNCTION: Binds phospholipid vesicles containing phosphatidylinositol 3-phosphate and participates in endosomal trafficking. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | SUDS3 | chr12:118841322 | chr12:93251261 | ENST00000543473 | + | 10 | 12 | 66_171 | 267 | 329.0 | Coiled coil | Ontology_term=ECO:0000255 |
| Tgene | EEA1 | chr12:118841322 | chr12:93251261 | ENST00000322349 | 2 | 29 | 1093_1231 | 81 | 1412.0 | Compositional bias | Note=Glu/Lys-rich | |
| Tgene | EEA1 | chr12:118841322 | chr12:93251261 | ENST00000322349 | 2 | 29 | 397_758 | 81 | 1412.0 | Compositional bias | Note=Gln/Glu/Lys-rich | |
| Tgene | EEA1 | chr12:118841322 | chr12:93251261 | ENST00000322349 | 2 | 29 | 937_1032 | 81 | 1412.0 | Compositional bias | Note=Gln/Glu/Lys-rich | |
| Tgene | EEA1 | chr12:118841322 | chr12:93251261 | ENST00000322349 | 2 | 29 | 1352_1410 | 81 | 1412.0 | Zinc finger | FYVE-type |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Tgene | EEA1 | chr12:118841322 | chr12:93251261 | ENST00000322349 | 2 | 29 | 74_1348 | 81 | 1412.0 | Coiled coil | Ontology_term=ECO:0000255 | |
| Tgene | EEA1 | chr12:118841322 | chr12:93251261 | ENST00000322349 | 2 | 29 | 41_64 | 81 | 1412.0 | Zinc finger | C2H2-type |
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Fusion Gene Sequence for SUDS3-EEA1 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones. |
| >87975_87975_1_SUDS3-EEA1_SUDS3_chr12_118841322_ENST00000397564_EEA1_chr12_93251261_ENST00000322349_length(transcript)=10310nt_BP=945nt GCGGAGACGGGGAAGGGGTCGCCGTGGCTGCCGGTCCTCGAGTTGGGGGCTGCCGCGGACACTGCTAGGCAGACGGCGAGTACCGAGCGC GGGTGGCCGCGGTGTCCGTGGGCCACGCTCAGCTGCGGTCAGAGGCGACATGAGTGCCGCGGGGCTGCTGGCCCCGGCCCCGGCCCAGGC TGGAGCGCCGCCGGCCCCCGAGTACTACCCCGAGGAGGATGAAGAGCTGGAGAGCGCCGAGGACGACGAGCGCAGCTGTCGGGGCCGCGA GTCGGACGAAGACACTGAGGATGCTAGTGAAACTGACCTGGCAAAGCATGATGAAGAAGACTATGTAGAAATGAAGGAACAGATGTATCA GGACAAACTGGCTTCTCTCAAGAGGCAGTTGCAACAACTGCAAGAAGGTACATTACAGGAATATCAGAAGAGAATGAAAAAACTAGATCA GCAGTACAAAGAGAGGATACGGAATGCAGACACACTGTTACTGCAAGCTCAGACTGAACAAGTGGAACGAAATTACATTAAAGAAAAGAA GGCAGCAGTGAAAGAATTTGAAGACAAGAAGGTTGAGCTGAAAGAGAACCTGATTGCTGAGCTAGAAGAAAAGAAGAAAATGATTGAAAA TGAAAAGCTGACAATGGAACTGACTGGAGATTCTATGGAGGTGAAACCTATCATGACCAGAAAGTTGCGGAGGCGACCAAATGATCCCGT CCCCATCCCAGACAAGAGGAGGAAACCTGCTCCAGCCCAGCTAAACTATTTGTTAACAGATGAACAGATCATGGAGGATCTGAGAACATT AAATAAGCTTAAGTCACCCAAGAGACCAGCATCTCCATCCTCTCCTGAGCACTTGCCTGCAACACCCGCGGAATCTCCAGCCCAGAGGTT CGAAGCTCGGATAGAAGATGGCAAACTGTACTATGACAAAAGATGAGATGATGTAACACTGCTCAGACAAGAGGTCCAAGACCTACAGGC TTCACTTAAGGAAGAAAAATGGTACTCGGAAGAATTAAAGAAGGAATTAGAAAAATATCAAGGGCTGCAGCAGCAAGAGGCCAAACCTGA TGGGTTGGTGACTGATTCATCAGCAGAACTACAGTCTTTGGAACAGCAATTAGAAGAAGCCCAAACAGAAAATTTTAATATTAAGCAAAT GAAAGACTTATTTGAACAGAAAGCAGCCCAACTTGCTACTGAAATTGCAGATATAAAGTCAAAGTATGATGAAGAAAGGAGTCTTCGAGA AGCTGCTGAACAAAAAGTGACACGTCTGACAGAAGAATTAAACAAAGAGGCAACTGTAATTCAAGATCTGAAGACGGAACTGCTTCAGAG ACCTGGTATAGAAGATGTTGCCGTGCTAAAGAAAGAACTGGTCCAAGTTCAAACACTAATGGATAACATGACCTTGGAACGTGAGCGAGA ATCTGAAAAACTCAAAGATGAATGCAAAAAATTGCAGTCACAATATGCTAGCTCAGAGGCCACAATAAGCCAGCTAAGGAGTGAACTTGC CAAAGGCCCCCAGGAAGTTGCTGTATATGTACAGGAACTACAAAAACTGAAAAGTTCAGTTAATGAATTAACACAAAAAAATCAGACCTT GACAGAAAACTTGCTGAAAAAAGAACAAGACTATACTAAGTTAGAGGAGAAACATAATGAAGAATCTGTGAGTAAAAAGAATATTCAGGC AACCCTTCATCAAAAAGACCTAGATTGTCAACAGCTTCAGTCAAGATTGTCTGCATCTGAAACCTCACTGCATAGAATACATGTAGAACT AAGTGAAAAAGGAGAAGCTACTCAAAAGCTCAAAGAAGAATTATCTGAGGTAGAGACCAAGTACCAGCATCTAAAGGCGGAGTTTAAGCA GCTACAACAACAGAGAGAAGAAAAGGAGCAGCATGGGTTACAACTCCAAAGTGAAATTAATCAATTACATAGCAAACTTCTGGAGACAGA GCGCCAACTAGGGGAAGCTCATGGTAGGCTGAAGGAACAGAGACAGCTTTCAAGTGAAAAGTTGATGGATAAAGAACAACAAGTGGCTGA TTTACAACTCAAACTTTCTCGGTTAGAAGAGCAGTTGAAGGAAAAAGTTACAAATTCTACAGAATTGCAGCATCAATTAGATAAAACAAA GCAACAGCATCAAGAACAACAGGCTCTTCAGCAAAGCACCACGGCAAAACTTCGAGAAGCTCAGAATGATTTGGAACAAGTTCTACGTCA AATTGGCGATAAGGACCAAAAGATCCAGAACCTTGAAGCTTTATTACAGAAGAGTAAAGAAAATATTTCATTACTAGAAAAAGAAAGAGA AGATCTTTATGCAAAAATTCAGGCTGGTGAAGGAGAGACTGCTGTTCTTAACCAGTTACAAGAAAAAAACCATACACTACAGGAGCAAGT AACTCAACTAACAGAGAAGCTGAAGAATCAGTCAGAAAGTCATAAACAAGCCCAGGAGAATTTGCATGACCAGGTACAAGAGCAGAAGGC ACATCTTAGAGCTGCACAAGACCGTGTCCTTTCCCTAGAAACTAGTGTCAATGAATTAAATAGTCAATTAAATGAAAGCAAGGAGAAGGT CTCCCAGCTTGACATACAGATTAAAGCCAAAACCGAACTATTACTATCAGCAGAAGCAGCAAAAACTGCTCAAAGAGCTGATCTTCAGAA TCATTTGGACACAGCTCAAAATGCATTACAAGATAAACAGCAGGAGTTAAATAAGATTACTACTCAGTTGGATCAGGTCACTGCAAAGTT ACAAGACAAGCAAGAACATTGCAGTCAGCTGGAAAGTCATCTTAAAGAATATAAAGAGAAATACCTCTCTTTAGAACAGAAAACCGAAGA GCTAGAAGGTCAAATTAAGAAACTAGAAGCTGATAGTCTTGAAGTTAAAGCAAGCAAGGAGCAGGCTTTGCAAGATCTACAACAGCAAAG ACAGCTGAACACAGATTTAGAGCTCAGAGCCACAGAATTGAGTAAACAACTTGAAATGGAGAAGGAAATAGTATCCAGTACAAGATTGGA TCTACAGAAAAAATCTGAAGCCCTTGAAAGTATCAAGCAAAAGCTTACCAAGCAAGAGGAAGAAAAAAAAATCCTGAAACAAGATTTTGA AACTTTAAGTCAAGAAACAAAGATTCAGCATGAGGAATTGAATAACAGAATTCAAACAACAGTAACAGAACTACAAAAAGTGAAAATGGA GAAAGAAGCTTTAATGACAGAGCTTTCTACAGTAAAGGACAAACTATCAAAAGTTTCTGATTCTTTGAAAAACTCTAAAAGTGAATTTGA AAAGGAGAATCAGAAAGGAAAAGCCGCTATATTAGACTTGGAAAAAACTTGCAAAGAATTAAAGCATCAACTTCAAGTGCAGATGGAAAA CACACTTAAGGAACAGAAGGAACTGAAAAAGTCACTTGAAAAAGAGAAGGAGGCTTCTCATCAGTTGAAATTGGAACTCAATTCAATGCA GGAACAACTTATACAGGCCCAGAATACTTTAAAACAAAATGAAAAAGAAGAGCAACAACTTCAGGGGAACATAAATGAGCTAAAGCAATC AAGTGAACAGAAGAAAAAACAAATTGAAGCACTCCAAGGAGAGCTTAAAATTGCTGTTTTACAGAAGACAGAGCTTGAGAATAAACTACA GCAGCAGTTAACACAGGCAGCCCAGGAACTTGCAGCAGAGAAAGAGAAAATATCAGTATTACAAAACAACTATGAAAAAAGTCAGGAAAC TTTCAAACAGCTTCAATCTGATTTCTATGGGAGGGAATCTGAACTTCTAGCCACCAGGCAAGATCTTAAGTCTGTAGAAGAGAAGCTTTC TCTAGCACAGGAGGACTTGATTTCAAACAGAAATCAAATTGGAAATCAAAATAAATTGATTCAAGAACTGAAGACTGCCAAGGCTACATT GGAGCAGGATTCAGCAAAGAAAGAACAGCAATTGCAGGAGCGATGTAAAGCACTACAAGACATTCAGAAAGAAAAGTCACTGAAAGAAAA AGAACTGGTAAATGAGAAGTCTAAATTGGCAGAGATAGAAGAAATTAAATGTAGACAAGAAAAAGAAATCACTAAACTAAACGAAGAACT CAAGTCCCACAAACTAGAAAGCATAAAGGAGATAACAAATCTTAAAGATGCTAAACAGCTTCTAATTCAGCAGAAATTAGAACTTCAAGG AAAAGCGGACTCCCTGAAGGCAGCTGTTGAACAGGAGAAGAGAAATCAGCAGATACTAAAAGACCAGGTGAAAAAGGAAGAAGAGGAGCT GAAGAAAGAATTTATTGAGAAAGAAGCTAAGTTGCATTCCGAAATAAAAGAAAAGGAAGTAGGAATGAAGAAGCATGAAGAAAATGAGGC TAAACTTACCATGCAGATTACAGCATTAAATGAAAACTTAGGCACTGTGAAGAAGGAGTGGCAATCTAGTCAACGGAGAGTTAGTGAGCT TGAGAAACAAACGGATGACTTACGGGGTGAAATTGCAGTATTAGAAGCAACGGTTCAGAATAATCAAGATGAAAGGAGAGCACTACTGGA AAGATGTCTTAAAGGAGAAGGTGAAATAGAAAAGCTTCAAACCAAAGTATTAGAATTGCAAAGAAAGCTGGATAATACAACTGCAGCAGT GCAGGAGCTGGGCAGAGAAAACCAATCACTTCAGATCAAACATACACAAGCGTTGAATAGAAAGTGGGCCGAAGACAATGAAGTACAAAA CTGTATGGCCTGTGGGAAAGGCTTTTCAGTAACAGTGAGACGGCATCACTGCCGACAGTGTGGAAATATCTTCTGTGCTGAATGTTCAGC CAAAAATGCCTTAACTCCTTCCTCCAAGAAGCCTGTTCGTGTCTGTGATGCATGTTTCAATGACTTGCAAGGATAATGGGTTATCACAAC TTCAGAGTAATATTACACTAACATTAGATTTTTAATAAATGTACTTAATAGAGGTCTTGGACTACTATTTGGTTTGGACACTGGTTGCAA TACTAGACCAAATAGGAATTAGTATATTTTGGAATGTTATGGATATCAAGTAAAACTCTTCTATTTTTGTGAGACTTGGGCTTATCATCT TTCATTACTTTTTTCCCATTTAGCCCCTGGAATAGCTTTCATGCCAAGTTTAGAATTAGCCAATGAAATGTAAATAAACTTTGGACAGAA AATAGCAATGTATTTTTTTAATATAATTTCATTATTCACAAATGAAGAATGCAATTCCATAGCTTACTTCTTTCTCCTAAATTTAATGTA CAAAAATGTACATGGATGATATTATCACTTGTTGCTGTTTTTGTTGCACAATAGCACATTAATTATATTAAATATTCTCTTTGTGAAGTT ATGCACAGAACTGTAACACTTTCCTCTGCCTTTTTCTCTTATATGTGGGTTCATGGTTCAGTTGCATTGTTATGTTATGAATTTACTACT TGGGTGTTCTAAATACAGTTTATCTTAAAATATGTAGTAATATGAATTCAAAAATGGTTTTTGTTTTAACAATATTAATTAAATTTTCTT GGGTGGATTTTATAAAAACCTCTGTAAAATCAATTTGTTTACTTATAGTTATCTGGGGTTGTATTGCAAAGAATAGGGTTAATTTTTCTT TTTGTCTTTTTCTGTCTCTTTCTTAAACTCCCACGCATTGTCCATTTAGAATCTTAGAAAGCTTCTTACCCTCGCTGTCAGTTGGAGGAT GAATAATAAACATTGTATAATGTTCTTATTCTCGGTTTCTTGTAAGTGGGAAGTCTTTTGAGATCAGCCTTCATATCATACCCTTATTTT GTCTCTCTAGCATCTTCAGGAACCTGAGTTTGCTTTTTACATAGATCTGATTTTTTCCTTTATTTGGTTTAACATTTTCAAGCATAGATC AGCTTCATGTATTTGTTTTATAATTTTGCATCTTAAAGCTAGTAACTAATATTGCTGTGGTCTTATTGGTGAAAACAAAATATAAAATGA TAAGAAGACATTAAATATTTTACTTTCTATTTCTTACCCTATTGGGAAGAATTTTTAAAAGTTGTAAAATTGACTTAAAGTTAAAATGGT TCTGAATTTGGTGTTCCATGTCAACTGTTCCCAGTTTTAATTTTAACTTTGCAAAAATAATGTTGTGAAATTCCCTTTAAGTAACTAACA CCTAGAAATAGAGTATCACCAAAAACAAATGTATTTAGGAATCCCAGTTACAATAAAAACTGAAACAGCATGGCTAAGCATCTTAAGGAT AATTAAGAAATTAGCTTATTTGTATGCTGAACAATGGAATCGAACTTTAATTTAGCATAGTCTTATTAATTTGGAAAATTGTAAAACATC TCAAGAGAGAAGTTATTAATATTGGTTTATTAATCTTTCTAGAGAAGAAGTGTAGTTATACATTCATTCAGTGCAATCATTTTATAACAG TAGTTAATATTTCATTTATAATAGTTCTTAATATACATTTGCTTTCAAATATTCTGAAATGAAATTATATTCATGCTATACCTACAGTGT ATGTAAACTAAAGAGATCACTACATATTTGTTTAATTATTTAAAAAAAAATTTAAGTAAACCCTGTTGTCATTAGCTATTAAGAACATTG ATTAAGTCCCTGGACTTGGATAAACATATATCCTTGAACATATATAATGAAGAAATACAGTGGCTCTTTATTAAAAATAATAGTTGGATA ATATAAACTGAACTATTTATGCATTTTTATATACTTATAAATCCTTCCAAATAGTTTTAATTCTATCCTTTTACATATAAATAACTTAAT AAGTGTGCTGGAAAAACACAGATATTCACAGCACCACTGTTTTTTTTTTTTTTTTGAGATAATAAATTCCATGAGAAATCTGGGTTTGAA TATTTGTTTACTTTGTCTCCTAATTGAACACCACTCCAGGCCTTCTGTCTGTCTCCCCTTTACCCCCAAAATACTCACAAAAAAATTTTA AGACAACAAGTAACCATATATAGGTGTTTGAATGATTTTCTCATTTTTATCTAATTTCATTTCATAAGTCCCGAGTAATTTACCTACCAT AGGCTACTATACTGATAATATAAATGAAACCGAACATTTTTTGCTACTAACTCTCCCCAATTTAATGTGTTTTCGAAATAAAAATTTAAA TTTTTTTCCTTTTAATTAAAAAGTCATCTTTGAAGTCCTTATTGGCTGTACATTTTACATGTTTGCTGGTACTATTATTTTGTCAGTCAG TTAAAGCTGGCATGTACAGCTCTTGGCTTTAATGAAAAGCACATTGACATAATGTTAGTAAATTCCAAACCCCGGCACAGAATGTGAGTT AAAATTAAGTCTTGCTGGGTTAGTGTACAATAAACTATACCTACAGACTTTTTTTTAATAGAAAGAAGACAAAGCTGCTGGTATAGGATT TGTTCCTTTGAAGAAAAAATGAGGGAAACAAACACAAAAACCTCAATGCAGTGTATAAATAACATTTTGTTCAACTACCTCTTAATGTGG AATTATCTACTTTAATAGTTTCCTGACAGTAATGTTAAATAGTAACTGCCAAATTTGTTATTTTCCCATCTCTCTTAAAAAAGTCTTTAT GATTATTTTATATAGTTTTGAGAACTTTAAAGCCACTTTTTTTTAACCTTACATTTGCATAAAAATGTTTAGCTTTTAAGTAGAGAGCAA ATTATGATCATATATTTTGATATTCATGACCTGTTTGACTATAGGAGTTTTTTTAAAAAAATGCACTTTGGCTATAAAACCATGGATGAT TTGATCCATAAGATTTAAATGTGCCACCATTATAGTATTCCTAGACATGAGCTTGATGAATGGTATTCTGTAATTATAACGTGCCACACA TTATTGTGTCTTAATTGCCCTTAGCCTGAATTTTAATGATCAATTTGTTATTGTTGCAGATGTGAATATTGTGCATAAACTTACTAAATT TATGTAAAATTGTATAAAATAGAATTAGAAGTCACTAAGTTCTTTCTGTGTAGAAGTAATAAATTTATTGTAACACAATGCAGTTGTGTA TATGACATTCTGTAATTCCTTGAACTGGATCATATATTCATAAGTTCTGTAGATACTTATGCATGAACATTTTCTCATTTAGTTTTTGGG TTCATTATTTGTATTGTGTTTACTACTTGTGATCATGTAGTTGTGCCTTACTTTGTGAGAAAGGTTAGCTCAGTAAATACTGCAATTTCT AAACTCAGTGATTGGAAGGTTATTAATTATAAATGTAACTGATAAAGTACGTGACAGCATTTAAATCTGTATAAAGAACAATGGAAGGAT CCTTATTGAATTGTTGCTTTTTTTTAATATGTTTAAATATTATATTAAAAACATTTCTTTCTAAACTAGTTGTATTCTGTGACTATAAAT TGTTTTGTCTAACAAAAGAGAGAACACTGTATTAACCATTTTGCATTAATTTATTTACAGAATATTAGGACTTTGCACTTGGATATAGAC AGTGGTGTTTTAATGTTGTTCAATTTCGAATAGTAATTAAATTCCTGATCTCAAGAGAAATTATTAATGCCATTTTGCCTTAGACATTCC ATTTAATATTGTAGAGAATTAACAAAACTAAAAACAAATATAAAAAATATGTAATTAACCCCTTATTTCATTGTGTGTCTGCATTTAATA CCCAGATGACCATTTAAAGATACTTAAAACATTATTTATTTATTTATTTATTTATTTTTCTCCCTCCCCTCCCCAAAGATACTTTTTGGA AGGCCCAATGTGCCATTGTTTTTTGCTATTTTTTCTTCCTGGGAGCCACGGTTCTAGAATGGTTTTTGTTCTGACCCCCGTGATCCCTTC ATTCGAATGTGCTTCATTCTAAACCCTCCAAAGAGTTTAATGTGCATATCCTCAAACATCTAATATATTGTATATTAGACATGTTACTTT GTGAGCTTTATAGAATTCCAGTTTATGTACAGCATATTCTTGAGCTGTTTTATATATTTTGTTAATTTAGTCAGTCTGTCTCTCCCTTTA ATGAGATTCAGAGGGAGAAAACTACCTTTATACATGTAAGTCTGTGGTTGCTGGATTCATGGGACTAAAGGAATTTGAGAGGCCACCTCA TCCTAGTCCACTGCTCACCTCCGAGGTTAGTTTATATCTAAACATTTGCAAGATGATTGTTAATGTAAAAATTTTTTTTAACCAGAAATT TCTTTATAAAATCTTCTCTTGCATAATCTATATTGTATTCTCCTGGACATAACTGCTTTCAGTCCCATCCAGATGCCATCTCTAGGAATT CACTTGAAGCTTGAAGTCTATTCTCCCCTTTTTCTCCCCTCCACCTCATTTATTCTTAGCTATTAACAATAGTTACTGTCCTCCAGATTT TCCTTTTTTTCTTCTATTAAATTTCTGACATTATTATAAAGAGGTTATTAGTCTCCATTCTAATAGTGCTTGCCTTGTACAAAAGCCTTT CTGCTGCACTTGTCTTTACTGCTTTGTTTGCATAGTGAAATTTCACCTTCCTCAAGGAATTACTGGGCACATGACTTGCCCAAACATTAT CCTCTCTACCCCATTCTTCAGCTTAACAAAATCAGCTAAGGCTTCAGTTGTCTTGCAGCCAAATTTGATAAATTTACTACTTTCACTTTG CAAATTGCAAAAGGTACGATTCTGAAATGGAAGTTTGTGGACTTCCCTTTGATGCAATAATCTGACCCTAAGAACTAGTTCCTTGAATGT AGTTAATAGTATATATCCTGCCATGATAATAATTATTCAAACTGCCTTTCATGATAAAAATTCTGAAGAAATTTGAAGTCCTGCCAAATA AAATTAAGTGACTGTACTGTGCTAACACACACACACACACACACACACACCAATCAAAACCAGAAAGTATTTTTATGGCAAACACCATCA TTCTTCAAAAAATAAAGTTAAGAGACAGATACCTTACTATGTCTATGAAAATCTGTACACTTCACAACAGGCCAAGAAAAGCCATGCAAA AGTGTTAACTGGTGAAAGCCAGATTTTTTTTTTCTTCCTATCTTAAAGTAATGGAATTTAGTCTTTGGGATTTTCTACTTCCACGTTAGA GTACTATATACCTGAGATGAGTTTGAGAATAGGAATTTTAAAACTGCTACTTAAATGTAGTCCCTATTTATTGCTTTGTATATTAAAAGA >87975_87975_1_SUDS3-EEA1_SUDS3_chr12_118841322_ENST00000397564_EEA1_chr12_93251261_ENST00000322349_length(amino acids)=1325AA_BP= MLRQEVQDLQASLKEEKWYSEELKKELEKYQGLQQQEAKPDGLVTDSSAELQSLEQQLEEAQTENFNIKQMKDLFEQKAAQLATEIADIK SKYDEERSLREAAEQKVTRLTEELNKEATVIQDLKTELLQRPGIEDVAVLKKELVQVQTLMDNMTLERERESEKLKDECKKLQSQYASSE ATISQLRSELAKGPQEVAVYVQELQKLKSSVNELTQKNQTLTENLLKKEQDYTKLEEKHNEESVSKKNIQATLHQKDLDCQQLQSRLSAS ETSLHRIHVELSEKGEATQKLKEELSEVETKYQHLKAEFKQLQQQREEKEQHGLQLQSEINQLHSKLLETERQLGEAHGRLKEQRQLSSE KLMDKEQQVADLQLKLSRLEEQLKEKVTNSTELQHQLDKTKQQHQEQQALQQSTTAKLREAQNDLEQVLRQIGDKDQKIQNLEALLQKSK ENISLLEKEREDLYAKIQAGEGETAVLNQLQEKNHTLQEQVTQLTEKLKNQSESHKQAQENLHDQVQEQKAHLRAAQDRVLSLETSVNEL NSQLNESKEKVSQLDIQIKAKTELLLSAEAAKTAQRADLQNHLDTAQNALQDKQQELNKITTQLDQVTAKLQDKQEHCSQLESHLKEYKE KYLSLEQKTEELEGQIKKLEADSLEVKASKEQALQDLQQQRQLNTDLELRATELSKQLEMEKEIVSSTRLDLQKKSEALESIKQKLTKQE EEKKILKQDFETLSQETKIQHEELNNRIQTTVTELQKVKMEKEALMTELSTVKDKLSKVSDSLKNSKSEFEKENQKGKAAILDLEKTCKE LKHQLQVQMENTLKEQKELKKSLEKEKEASHQLKLELNSMQEQLIQAQNTLKQNEKEEQQLQGNINELKQSSEQKKKQIEALQGELKIAV LQKTELENKLQQQLTQAAQELAAEKEKISVLQNNYEKSQETFKQLQSDFYGRESELLATRQDLKSVEEKLSLAQEDLISNRNQIGNQNKL IQELKTAKATLEQDSAKKEQQLQERCKALQDIQKEKSLKEKELVNEKSKLAEIEEIKCRQEKEITKLNEELKSHKLESIKEITNLKDAKQ LLIQQKLELQGKADSLKAAVEQEKRNQQILKDQVKKEEEELKKEFIEKEAKLHSEIKEKEVGMKKHEENEAKLTMQITALNENLGTVKKE WQSSQRRVSELEKQTDDLRGEIAVLEATVQNNQDERRALLERCLKGEGEIEKLQTKVLELQRKLDNTTAAVQELGRENQSLQIKHTQALN -------------------------------------------------------------- >87975_87975_2_SUDS3-EEA1_SUDS3_chr12_118841322_ENST00000543473_EEA1_chr12_93251261_ENST00000322349_length(transcript)=10480nt_BP=1115nt GGATTTTAAGACGGCGATGAAAGGGCTGAGGTTGTGGCGACGGGGGCGTCCAGCGGCATCTCCACTCCCCCAAGGATGGCGGAATCAGGC CGTTGTCGGGCAGCTCTCGACCCGGAAGTCGCTCGCGGCGCGAGGCCCCCGTTGCCGAGCGCGGGCGCGGGGGGCGGAGCTCGGCGGAGA CGGGGAAGGGGTCGCCGTGGCTGCCGGTCCTCGAGTTGGGGGCTGCCGCGGACACTGCTAGGCAGACGGCGAGTACCGAGCGCGGGTGGC CGCGGTGTCCGTGGGCCACGCTCAGCTGCGGTCAGAGGCGACATGAGTGCCGCGGGGCTGCTGGCCCCGGCCCCGGCCCAGGCTGGAGCG CCGCCGGCCCCCGAGTACTACCCCGAGGAGGATGAAGAGCTGGAGAGCGCCGAGGACGACGAGCGCAGCTGTCGGGGCCGCGAGTCGGAC GAAGACACTGAGGATGCTAGTGAAACTGACCTGGCAAAGCATGATGAAGAAGACTATGTAGAAATGAAGGAACAGATGTATCAGGACAAA CTGGCTTCTCTCAAGAGGCAGTTGCAACAACTGCAAGAAGGTACATTACAGGAATATCAGAAGAGAATGAAAAAACTAGATCAGCAGTAC AAAGAGAGGATACGGAATGCAGAACTCTTCCTCCAGCTGGAAACTGAACAAGTGGAACGAAATTACATTAAAGAAAAGAAGGCAGCAGTG AAAGAATTTGAAGACAAGAAGGTTGAGCTGAAAGAGAACCTGATTGCTGAGCTAGAAGAAAAGAAGAAAATGATTGAAAATGAAAAGCTG ACAATGGAACTGACTGGAGATTCTATGGAGGTGAAACCTATCATGACCAGAAAGTTGCGGAGGCGACCAAATGATCCCGTCCCCATCCCA GACAAGAGGAGGAAACCTGCTCCAGCCCAGCTAAACTATTTGTTAACAGATGAACAGATCATGGAGGATCTGAGAACATTAAATAAGCTT AAGTCACCCAAGAGACCAGCATCTCCATCCTCTCCTGAGCACTTGCCTGCAACACCCGCGGAATCTCCAGCCCAGAGGTTCGAAGCTCGG ATAGAAGATGGCAAACTGTACTATGACAAAAGATGAGATGATGTAACACTGCTCAGACAAGAGGTCCAAGACCTACAGGCTTCACTTAAG GAAGAAAAATGGTACTCGGAAGAATTAAAGAAGGAATTAGAAAAATATCAAGGGCTGCAGCAGCAAGAGGCCAAACCTGATGGGTTGGTG ACTGATTCATCAGCAGAACTACAGTCTTTGGAACAGCAATTAGAAGAAGCCCAAACAGAAAATTTTAATATTAAGCAAATGAAAGACTTA TTTGAACAGAAAGCAGCCCAACTTGCTACTGAAATTGCAGATATAAAGTCAAAGTATGATGAAGAAAGGAGTCTTCGAGAAGCTGCTGAA CAAAAAGTGACACGTCTGACAGAAGAATTAAACAAAGAGGCAACTGTAATTCAAGATCTGAAGACGGAACTGCTTCAGAGACCTGGTATA GAAGATGTTGCCGTGCTAAAGAAAGAACTGGTCCAAGTTCAAACACTAATGGATAACATGACCTTGGAACGTGAGCGAGAATCTGAAAAA CTCAAAGATGAATGCAAAAAATTGCAGTCACAATATGCTAGCTCAGAGGCCACAATAAGCCAGCTAAGGAGTGAACTTGCCAAAGGCCCC CAGGAAGTTGCTGTATATGTACAGGAACTACAAAAACTGAAAAGTTCAGTTAATGAATTAACACAAAAAAATCAGACCTTGACAGAAAAC TTGCTGAAAAAAGAACAAGACTATACTAAGTTAGAGGAGAAACATAATGAAGAATCTGTGAGTAAAAAGAATATTCAGGCAACCCTTCAT CAAAAAGACCTAGATTGTCAACAGCTTCAGTCAAGATTGTCTGCATCTGAAACCTCACTGCATAGAATACATGTAGAACTAAGTGAAAAA GGAGAAGCTACTCAAAAGCTCAAAGAAGAATTATCTGAGGTAGAGACCAAGTACCAGCATCTAAAGGCGGAGTTTAAGCAGCTACAACAA CAGAGAGAAGAAAAGGAGCAGCATGGGTTACAACTCCAAAGTGAAATTAATCAATTACATAGCAAACTTCTGGAGACAGAGCGCCAACTA GGGGAAGCTCATGGTAGGCTGAAGGAACAGAGACAGCTTTCAAGTGAAAAGTTGATGGATAAAGAACAACAAGTGGCTGATTTACAACTC AAACTTTCTCGGTTAGAAGAGCAGTTGAAGGAAAAAGTTACAAATTCTACAGAATTGCAGCATCAATTAGATAAAACAAAGCAACAGCAT CAAGAACAACAGGCTCTTCAGCAAAGCACCACGGCAAAACTTCGAGAAGCTCAGAATGATTTGGAACAAGTTCTACGTCAAATTGGCGAT AAGGACCAAAAGATCCAGAACCTTGAAGCTTTATTACAGAAGAGTAAAGAAAATATTTCATTACTAGAAAAAGAAAGAGAAGATCTTTAT GCAAAAATTCAGGCTGGTGAAGGAGAGACTGCTGTTCTTAACCAGTTACAAGAAAAAAACCATACACTACAGGAGCAAGTAACTCAACTA ACAGAGAAGCTGAAGAATCAGTCAGAAAGTCATAAACAAGCCCAGGAGAATTTGCATGACCAGGTACAAGAGCAGAAGGCACATCTTAGA GCTGCACAAGACCGTGTCCTTTCCCTAGAAACTAGTGTCAATGAATTAAATAGTCAATTAAATGAAAGCAAGGAGAAGGTCTCCCAGCTT GACATACAGATTAAAGCCAAAACCGAACTATTACTATCAGCAGAAGCAGCAAAAACTGCTCAAAGAGCTGATCTTCAGAATCATTTGGAC ACAGCTCAAAATGCATTACAAGATAAACAGCAGGAGTTAAATAAGATTACTACTCAGTTGGATCAGGTCACTGCAAAGTTACAAGACAAG CAAGAACATTGCAGTCAGCTGGAAAGTCATCTTAAAGAATATAAAGAGAAATACCTCTCTTTAGAACAGAAAACCGAAGAGCTAGAAGGT CAAATTAAGAAACTAGAAGCTGATAGTCTTGAAGTTAAAGCAAGCAAGGAGCAGGCTTTGCAAGATCTACAACAGCAAAGACAGCTGAAC ACAGATTTAGAGCTCAGAGCCACAGAATTGAGTAAACAACTTGAAATGGAGAAGGAAATAGTATCCAGTACAAGATTGGATCTACAGAAA AAATCTGAAGCCCTTGAAAGTATCAAGCAAAAGCTTACCAAGCAAGAGGAAGAAAAAAAAATCCTGAAACAAGATTTTGAAACTTTAAGT CAAGAAACAAAGATTCAGCATGAGGAATTGAATAACAGAATTCAAACAACAGTAACAGAACTACAAAAAGTGAAAATGGAGAAAGAAGCT TTAATGACAGAGCTTTCTACAGTAAAGGACAAACTATCAAAAGTTTCTGATTCTTTGAAAAACTCTAAAAGTGAATTTGAAAAGGAGAAT CAGAAAGGAAAAGCCGCTATATTAGACTTGGAAAAAACTTGCAAAGAATTAAAGCATCAACTTCAAGTGCAGATGGAAAACACACTTAAG GAACAGAAGGAACTGAAAAAGTCACTTGAAAAAGAGAAGGAGGCTTCTCATCAGTTGAAATTGGAACTCAATTCAATGCAGGAACAACTT ATACAGGCCCAGAATACTTTAAAACAAAATGAAAAAGAAGAGCAACAACTTCAGGGGAACATAAATGAGCTAAAGCAATCAAGTGAACAG AAGAAAAAACAAATTGAAGCACTCCAAGGAGAGCTTAAAATTGCTGTTTTACAGAAGACAGAGCTTGAGAATAAACTACAGCAGCAGTTA ACACAGGCAGCCCAGGAACTTGCAGCAGAGAAAGAGAAAATATCAGTATTACAAAACAACTATGAAAAAAGTCAGGAAACTTTCAAACAG CTTCAATCTGATTTCTATGGGAGGGAATCTGAACTTCTAGCCACCAGGCAAGATCTTAAGTCTGTAGAAGAGAAGCTTTCTCTAGCACAG GAGGACTTGATTTCAAACAGAAATCAAATTGGAAATCAAAATAAATTGATTCAAGAACTGAAGACTGCCAAGGCTACATTGGAGCAGGAT TCAGCAAAGAAAGAACAGCAATTGCAGGAGCGATGTAAAGCACTACAAGACATTCAGAAAGAAAAGTCACTGAAAGAAAAAGAACTGGTA AATGAGAAGTCTAAATTGGCAGAGATAGAAGAAATTAAATGTAGACAAGAAAAAGAAATCACTAAACTAAACGAAGAACTCAAGTCCCAC AAACTAGAAAGCATAAAGGAGATAACAAATCTTAAAGATGCTAAACAGCTTCTAATTCAGCAGAAATTAGAACTTCAAGGAAAAGCGGAC TCCCTGAAGGCAGCTGTTGAACAGGAGAAGAGAAATCAGCAGATACTAAAAGACCAGGTGAAAAAGGAAGAAGAGGAGCTGAAGAAAGAA TTTATTGAGAAAGAAGCTAAGTTGCATTCCGAAATAAAAGAAAAGGAAGTAGGAATGAAGAAGCATGAAGAAAATGAGGCTAAACTTACC ATGCAGATTACAGCATTAAATGAAAACTTAGGCACTGTGAAGAAGGAGTGGCAATCTAGTCAACGGAGAGTTAGTGAGCTTGAGAAACAA ACGGATGACTTACGGGGTGAAATTGCAGTATTAGAAGCAACGGTTCAGAATAATCAAGATGAAAGGAGAGCACTACTGGAAAGATGTCTT AAAGGAGAAGGTGAAATAGAAAAGCTTCAAACCAAAGTATTAGAATTGCAAAGAAAGCTGGATAATACAACTGCAGCAGTGCAGGAGCTG GGCAGAGAAAACCAATCACTTCAGATCAAACATACACAAGCGTTGAATAGAAAGTGGGCCGAAGACAATGAAGTACAAAACTGTATGGCC TGTGGGAAAGGCTTTTCAGTAACAGTGAGACGGCATCACTGCCGACAGTGTGGAAATATCTTCTGTGCTGAATGTTCAGCCAAAAATGCC TTAACTCCTTCCTCCAAGAAGCCTGTTCGTGTCTGTGATGCATGTTTCAATGACTTGCAAGGATAATGGGTTATCACAACTTCAGAGTAA TATTACACTAACATTAGATTTTTAATAAATGTACTTAATAGAGGTCTTGGACTACTATTTGGTTTGGACACTGGTTGCAATACTAGACCA AATAGGAATTAGTATATTTTGGAATGTTATGGATATCAAGTAAAACTCTTCTATTTTTGTGAGACTTGGGCTTATCATCTTTCATTACTT TTTTCCCATTTAGCCCCTGGAATAGCTTTCATGCCAAGTTTAGAATTAGCCAATGAAATGTAAATAAACTTTGGACAGAAAATAGCAATG TATTTTTTTAATATAATTTCATTATTCACAAATGAAGAATGCAATTCCATAGCTTACTTCTTTCTCCTAAATTTAATGTACAAAAATGTA CATGGATGATATTATCACTTGTTGCTGTTTTTGTTGCACAATAGCACATTAATTATATTAAATATTCTCTTTGTGAAGTTATGCACAGAA CTGTAACACTTTCCTCTGCCTTTTTCTCTTATATGTGGGTTCATGGTTCAGTTGCATTGTTATGTTATGAATTTACTACTTGGGTGTTCT AAATACAGTTTATCTTAAAATATGTAGTAATATGAATTCAAAAATGGTTTTTGTTTTAACAATATTAATTAAATTTTCTTGGGTGGATTT TATAAAAACCTCTGTAAAATCAATTTGTTTACTTATAGTTATCTGGGGTTGTATTGCAAAGAATAGGGTTAATTTTTCTTTTTGTCTTTT TCTGTCTCTTTCTTAAACTCCCACGCATTGTCCATTTAGAATCTTAGAAAGCTTCTTACCCTCGCTGTCAGTTGGAGGATGAATAATAAA CATTGTATAATGTTCTTATTCTCGGTTTCTTGTAAGTGGGAAGTCTTTTGAGATCAGCCTTCATATCATACCCTTATTTTGTCTCTCTAG CATCTTCAGGAACCTGAGTTTGCTTTTTACATAGATCTGATTTTTTCCTTTATTTGGTTTAACATTTTCAAGCATAGATCAGCTTCATGT ATTTGTTTTATAATTTTGCATCTTAAAGCTAGTAACTAATATTGCTGTGGTCTTATTGGTGAAAACAAAATATAAAATGATAAGAAGACA TTAAATATTTTACTTTCTATTTCTTACCCTATTGGGAAGAATTTTTAAAAGTTGTAAAATTGACTTAAAGTTAAAATGGTTCTGAATTTG GTGTTCCATGTCAACTGTTCCCAGTTTTAATTTTAACTTTGCAAAAATAATGTTGTGAAATTCCCTTTAAGTAACTAACACCTAGAAATA GAGTATCACCAAAAACAAATGTATTTAGGAATCCCAGTTACAATAAAAACTGAAACAGCATGGCTAAGCATCTTAAGGATAATTAAGAAA TTAGCTTATTTGTATGCTGAACAATGGAATCGAACTTTAATTTAGCATAGTCTTATTAATTTGGAAAATTGTAAAACATCTCAAGAGAGA AGTTATTAATATTGGTTTATTAATCTTTCTAGAGAAGAAGTGTAGTTATACATTCATTCAGTGCAATCATTTTATAACAGTAGTTAATAT TTCATTTATAATAGTTCTTAATATACATTTGCTTTCAAATATTCTGAAATGAAATTATATTCATGCTATACCTACAGTGTATGTAAACTA AAGAGATCACTACATATTTGTTTAATTATTTAAAAAAAAATTTAAGTAAACCCTGTTGTCATTAGCTATTAAGAACATTGATTAAGTCCC TGGACTTGGATAAACATATATCCTTGAACATATATAATGAAGAAATACAGTGGCTCTTTATTAAAAATAATAGTTGGATAATATAAACTG AACTATTTATGCATTTTTATATACTTATAAATCCTTCCAAATAGTTTTAATTCTATCCTTTTACATATAAATAACTTAATAAGTGTGCTG GAAAAACACAGATATTCACAGCACCACTGTTTTTTTTTTTTTTTTGAGATAATAAATTCCATGAGAAATCTGGGTTTGAATATTTGTTTA CTTTGTCTCCTAATTGAACACCACTCCAGGCCTTCTGTCTGTCTCCCCTTTACCCCCAAAATACTCACAAAAAAATTTTAAGACAACAAG TAACCATATATAGGTGTTTGAATGATTTTCTCATTTTTATCTAATTTCATTTCATAAGTCCCGAGTAATTTACCTACCATAGGCTACTAT ACTGATAATATAAATGAAACCGAACATTTTTTGCTACTAACTCTCCCCAATTTAATGTGTTTTCGAAATAAAAATTTAAATTTTTTTCCT TTTAATTAAAAAGTCATCTTTGAAGTCCTTATTGGCTGTACATTTTACATGTTTGCTGGTACTATTATTTTGTCAGTCAGTTAAAGCTGG CATGTACAGCTCTTGGCTTTAATGAAAAGCACATTGACATAATGTTAGTAAATTCCAAACCCCGGCACAGAATGTGAGTTAAAATTAAGT CTTGCTGGGTTAGTGTACAATAAACTATACCTACAGACTTTTTTTTAATAGAAAGAAGACAAAGCTGCTGGTATAGGATTTGTTCCTTTG AAGAAAAAATGAGGGAAACAAACACAAAAACCTCAATGCAGTGTATAAATAACATTTTGTTCAACTACCTCTTAATGTGGAATTATCTAC TTTAATAGTTTCCTGACAGTAATGTTAAATAGTAACTGCCAAATTTGTTATTTTCCCATCTCTCTTAAAAAAGTCTTTATGATTATTTTA TATAGTTTTGAGAACTTTAAAGCCACTTTTTTTTAACCTTACATTTGCATAAAAATGTTTAGCTTTTAAGTAGAGAGCAAATTATGATCA TATATTTTGATATTCATGACCTGTTTGACTATAGGAGTTTTTTTAAAAAAATGCACTTTGGCTATAAAACCATGGATGATTTGATCCATA AGATTTAAATGTGCCACCATTATAGTATTCCTAGACATGAGCTTGATGAATGGTATTCTGTAATTATAACGTGCCACACATTATTGTGTC TTAATTGCCCTTAGCCTGAATTTTAATGATCAATTTGTTATTGTTGCAGATGTGAATATTGTGCATAAACTTACTAAATTTATGTAAAAT TGTATAAAATAGAATTAGAAGTCACTAAGTTCTTTCTGTGTAGAAGTAATAAATTTATTGTAACACAATGCAGTTGTGTATATGACATTC TGTAATTCCTTGAACTGGATCATATATTCATAAGTTCTGTAGATACTTATGCATGAACATTTTCTCATTTAGTTTTTGGGTTCATTATTT GTATTGTGTTTACTACTTGTGATCATGTAGTTGTGCCTTACTTTGTGAGAAAGGTTAGCTCAGTAAATACTGCAATTTCTAAACTCAGTG ATTGGAAGGTTATTAATTATAAATGTAACTGATAAAGTACGTGACAGCATTTAAATCTGTATAAAGAACAATGGAAGGATCCTTATTGAA TTGTTGCTTTTTTTTAATATGTTTAAATATTATATTAAAAACATTTCTTTCTAAACTAGTTGTATTCTGTGACTATAAATTGTTTTGTCT AACAAAAGAGAGAACACTGTATTAACCATTTTGCATTAATTTATTTACAGAATATTAGGACTTTGCACTTGGATATAGACAGTGGTGTTT TAATGTTGTTCAATTTCGAATAGTAATTAAATTCCTGATCTCAAGAGAAATTATTAATGCCATTTTGCCTTAGACATTCCATTTAATATT GTAGAGAATTAACAAAACTAAAAACAAATATAAAAAATATGTAATTAACCCCTTATTTCATTGTGTGTCTGCATTTAATACCCAGATGAC CATTTAAAGATACTTAAAACATTATTTATTTATTTATTTATTTATTTTTCTCCCTCCCCTCCCCAAAGATACTTTTTGGAAGGCCCAATG TGCCATTGTTTTTTGCTATTTTTTCTTCCTGGGAGCCACGGTTCTAGAATGGTTTTTGTTCTGACCCCCGTGATCCCTTCATTCGAATGT GCTTCATTCTAAACCCTCCAAAGAGTTTAATGTGCATATCCTCAAACATCTAATATATTGTATATTAGACATGTTACTTTGTGAGCTTTA TAGAATTCCAGTTTATGTACAGCATATTCTTGAGCTGTTTTATATATTTTGTTAATTTAGTCAGTCTGTCTCTCCCTTTAATGAGATTCA GAGGGAGAAAACTACCTTTATACATGTAAGTCTGTGGTTGCTGGATTCATGGGACTAAAGGAATTTGAGAGGCCACCTCATCCTAGTCCA CTGCTCACCTCCGAGGTTAGTTTATATCTAAACATTTGCAAGATGATTGTTAATGTAAAAATTTTTTTTAACCAGAAATTTCTTTATAAA ATCTTCTCTTGCATAATCTATATTGTATTCTCCTGGACATAACTGCTTTCAGTCCCATCCAGATGCCATCTCTAGGAATTCACTTGAAGC TTGAAGTCTATTCTCCCCTTTTTCTCCCCTCCACCTCATTTATTCTTAGCTATTAACAATAGTTACTGTCCTCCAGATTTTCCTTTTTTT CTTCTATTAAATTTCTGACATTATTATAAAGAGGTTATTAGTCTCCATTCTAATAGTGCTTGCCTTGTACAAAAGCCTTTCTGCTGCACT TGTCTTTACTGCTTTGTTTGCATAGTGAAATTTCACCTTCCTCAAGGAATTACTGGGCACATGACTTGCCCAAACATTATCCTCTCTACC CCATTCTTCAGCTTAACAAAATCAGCTAAGGCTTCAGTTGTCTTGCAGCCAAATTTGATAAATTTACTACTTTCACTTTGCAAATTGCAA AAGGTACGATTCTGAAATGGAAGTTTGTGGACTTCCCTTTGATGCAATAATCTGACCCTAAGAACTAGTTCCTTGAATGTAGTTAATAGT ATATATCCTGCCATGATAATAATTATTCAAACTGCCTTTCATGATAAAAATTCTGAAGAAATTTGAAGTCCTGCCAAATAAAATTAAGTG ACTGTACTGTGCTAACACACACACACACACACACACACACCAATCAAAACCAGAAAGTATTTTTATGGCAAACACCATCATTCTTCAAAA AATAAAGTTAAGAGACAGATACCTTACTATGTCTATGAAAATCTGTACACTTCACAACAGGCCAAGAAAAGCCATGCAAAAGTGTTAACT GGTGAAAGCCAGATTTTTTTTTTCTTCCTATCTTAAAGTAATGGAATTTAGTCTTTGGGATTTTCTACTTCCACGTTAGAGTACTATATA CCTGAGATGAGTTTGAGAATAGGAATTTTAAAACTGCTACTTAAATGTAGTCCCTATTTATTGCTTTGTATATTAAAAGAACAATCAAGC >87975_87975_2_SUDS3-EEA1_SUDS3_chr12_118841322_ENST00000543473_EEA1_chr12_93251261_ENST00000322349_length(amino acids)=1325AA_BP= MLRQEVQDLQASLKEEKWYSEELKKELEKYQGLQQQEAKPDGLVTDSSAELQSLEQQLEEAQTENFNIKQMKDLFEQKAAQLATEIADIK SKYDEERSLREAAEQKVTRLTEELNKEATVIQDLKTELLQRPGIEDVAVLKKELVQVQTLMDNMTLERERESEKLKDECKKLQSQYASSE ATISQLRSELAKGPQEVAVYVQELQKLKSSVNELTQKNQTLTENLLKKEQDYTKLEEKHNEESVSKKNIQATLHQKDLDCQQLQSRLSAS ETSLHRIHVELSEKGEATQKLKEELSEVETKYQHLKAEFKQLQQQREEKEQHGLQLQSEINQLHSKLLETERQLGEAHGRLKEQRQLSSE KLMDKEQQVADLQLKLSRLEEQLKEKVTNSTELQHQLDKTKQQHQEQQALQQSTTAKLREAQNDLEQVLRQIGDKDQKIQNLEALLQKSK ENISLLEKEREDLYAKIQAGEGETAVLNQLQEKNHTLQEQVTQLTEKLKNQSESHKQAQENLHDQVQEQKAHLRAAQDRVLSLETSVNEL NSQLNESKEKVSQLDIQIKAKTELLLSAEAAKTAQRADLQNHLDTAQNALQDKQQELNKITTQLDQVTAKLQDKQEHCSQLESHLKEYKE KYLSLEQKTEELEGQIKKLEADSLEVKASKEQALQDLQQQRQLNTDLELRATELSKQLEMEKEIVSSTRLDLQKKSEALESIKQKLTKQE EEKKILKQDFETLSQETKIQHEELNNRIQTTVTELQKVKMEKEALMTELSTVKDKLSKVSDSLKNSKSEFEKENQKGKAAILDLEKTCKE LKHQLQVQMENTLKEQKELKKSLEKEKEASHQLKLELNSMQEQLIQAQNTLKQNEKEEQQLQGNINELKQSSEQKKKQIEALQGELKIAV LQKTELENKLQQQLTQAAQELAAEKEKISVLQNNYEKSQETFKQLQSDFYGRESELLATRQDLKSVEEKLSLAQEDLISNRNQIGNQNKL IQELKTAKATLEQDSAKKEQQLQERCKALQDIQKEKSLKEKELVNEKSKLAEIEEIKCRQEKEITKLNEELKSHKLESIKEITNLKDAKQ LLIQQKLELQGKADSLKAAVEQEKRNQQILKDQVKKEEEELKKEFIEKEAKLHSEIKEKEVGMKKHEENEAKLTMQITALNENLGTVKKE WQSSQRRVSELEKQTDDLRGEIAVLEATVQNNQDERRALLERCLKGEGEIEKLQTKVLELQRKLDNTTAAVQELGRENQSLQIKHTQALN -------------------------------------------------------------- |
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Fusion Gene PPI Analysis for SUDS3-EEA1 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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Related Drugs for SUDS3-EEA1 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.8 2021-05-08) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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Related Diseases for SUDS3-EEA1 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
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