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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:SUGP2-CLPTM1L (FusionGDB2 ID:88002)

Fusion Gene Summary for SUGP2-CLPTM1L

check button Fusion gene summary
Fusion gene informationFusion gene name: SUGP2-CLPTM1L
Fusion gene ID: 88002
HgeneTgene
Gene symbol

SUGP2

CLPTM1L

Gene ID

10147

81037

Gene nameSURP and G-patch domain containing 2CLPTM1 like
SynonymsSFRS14|SRFS14CRR9
Cytomap

19p13.11

5p15.33

Type of geneprotein-codingprotein-coding
DescriptionSURP and G-patch domain-containing protein 2arginine/serine-rich-splicing factor 14splicing factor, arginine/serine-rich 14cleft lip and palate transmembrane protein 1-like proteinCLPTM1-like proteincisplatin resistance related protein CRR9pcisplatin resistance-related protein 9
Modification date2020031320200313
UniProtAcc.

Q96KA5

Ensembl transtripts involved in fusion geneENST00000337018, ENST00000452918, 
ENST00000456085, ENST00000600377, 
ENST00000601879, ENST00000598202, 
ENST00000506641, ENST00000320895, 
ENST00000320927, ENST00000507807, 
Fusion gene scores* DoF score9 X 9 X 5=40515 X 11 X 8=1320
# samples 1017
** MAII scorelog2(10/405*10)=-2.01792190799726
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(17/1320*10)=-2.95693127810811
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: SUGP2 [Title/Abstract] AND CLPTM1L [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointSUGP2(19114977)-CLPTM1L(1318568), # samples:1
Anticipated loss of major functional domain due to fusion event.SUGP2-CLPTM1L seems lost the major protein functional domain in Hgene partner, which is a essential gene due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check buttonFusion gene breakpoints across SUGP2 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across CLPTM1L (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4STADTCGA-CG-5721-01ASUGP2chr19

19114977

-CLPTM1Lchr5

1318568

-


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Fusion Gene ORF analysis for SUGP2-CLPTM1L

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-5UTRENST00000337018ENST00000506641SUGP2chr19

19114977

-CLPTM1Lchr5

1318568

-
5CDS-5UTRENST00000452918ENST00000506641SUGP2chr19

19114977

-CLPTM1Lchr5

1318568

-
5CDS-5UTRENST00000456085ENST00000506641SUGP2chr19

19114977

-CLPTM1Lchr5

1318568

-
5CDS-5UTRENST00000600377ENST00000506641SUGP2chr19

19114977

-CLPTM1Lchr5

1318568

-
5CDS-5UTRENST00000601879ENST00000506641SUGP2chr19

19114977

-CLPTM1Lchr5

1318568

-
Frame-shiftENST00000337018ENST00000320895SUGP2chr19

19114977

-CLPTM1Lchr5

1318568

-
Frame-shiftENST00000337018ENST00000320927SUGP2chr19

19114977

-CLPTM1Lchr5

1318568

-
Frame-shiftENST00000452918ENST00000320895SUGP2chr19

19114977

-CLPTM1Lchr5

1318568

-
Frame-shiftENST00000452918ENST00000320927SUGP2chr19

19114977

-CLPTM1Lchr5

1318568

-
Frame-shiftENST00000456085ENST00000320927SUGP2chr19

19114977

-CLPTM1Lchr5

1318568

-
Frame-shiftENST00000456085ENST00000507807SUGP2chr19

19114977

-CLPTM1Lchr5

1318568

-
Frame-shiftENST00000600377ENST00000320895SUGP2chr19

19114977

-CLPTM1Lchr5

1318568

-
Frame-shiftENST00000600377ENST00000507807SUGP2chr19

19114977

-CLPTM1Lchr5

1318568

-
Frame-shiftENST00000601879ENST00000320927SUGP2chr19

19114977

-CLPTM1Lchr5

1318568

-
Frame-shiftENST00000601879ENST00000507807SUGP2chr19

19114977

-CLPTM1Lchr5

1318568

-
In-frameENST00000337018ENST00000507807SUGP2chr19

19114977

-CLPTM1Lchr5

1318568

-
In-frameENST00000452918ENST00000507807SUGP2chr19

19114977

-CLPTM1Lchr5

1318568

-
In-frameENST00000456085ENST00000320895SUGP2chr19

19114977

-CLPTM1Lchr5

1318568

-
In-frameENST00000600377ENST00000320927SUGP2chr19

19114977

-CLPTM1Lchr5

1318568

-
In-frameENST00000601879ENST00000320895SUGP2chr19

19114977

-CLPTM1Lchr5

1318568

-
intron-3CDSENST00000598202ENST00000320895SUGP2chr19

19114977

-CLPTM1Lchr5

1318568

-
intron-3CDSENST00000598202ENST00000320927SUGP2chr19

19114977

-CLPTM1Lchr5

1318568

-
intron-3CDSENST00000598202ENST00000507807SUGP2chr19

19114977

-CLPTM1Lchr5

1318568

-
intron-5UTRENST00000598202ENST00000506641SUGP2chr19

19114977

-CLPTM1Lchr5

1318568

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000337018SUGP2chr1919114977-ENST00000507807CLPTM1Lchr51318568-376430638030911003
ENST00000452918SUGP2chr1919114977-ENST00000507807CLPTM1Lchr51318568-370430032030311003
ENST00000601879SUGP2chr1919114977-ENST00000320895CLPTM1Lchr51318568-3937322713332551040
ENST00000600377SUGP2chr1919114977-ENST00000320927CLPTM1Lchr51318568-35772991203019999
ENST00000456085SUGP2chr1919114977-ENST00000320895CLPTM1Lchr51318568-320024902542518754

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000337018ENST00000507807SUGP2chr1919114977-CLPTM1Lchr51318568-0.0006021120.9993979
ENST00000452918ENST00000507807SUGP2chr1919114977-CLPTM1Lchr51318568-0.0005915230.9994085
ENST00000601879ENST00000320895SUGP2chr1919114977-CLPTM1Lchr51318568-0.0006781180.99932194
ENST00000600377ENST00000320927SUGP2chr1919114977-CLPTM1Lchr51318568-0.0005819430.999418
ENST00000456085ENST00000320895SUGP2chr1919114977-CLPTM1Lchr51318568-0.0045544420.9954456

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Fusion Genomic Features for SUGP2-CLPTM1L


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for SUGP2-CLPTM1L


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr19:19114977/chr5:1318568)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
.CLPTM1L

Q96KA5

FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Enhances cisplatin-mediated apoptosis, when overexpressed. {ECO:0000269|PubMed:11162647}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneSUGP2chr19:19114977chr5:1318568ENST00000337018-711738_7769761124.0Compositional biasNote=Pro/Ser-rich
HgeneSUGP2chr19:19114977chr5:1318568ENST00000337018-711869_9059761124.0Compositional biasNote=Asp/Glu-rich
HgeneSUGP2chr19:19114977chr5:1318568ENST00000452918-711738_7769761522.3333333333333Compositional biasNote=Pro/Ser-rich
HgeneSUGP2chr19:19114977chr5:1318568ENST00000452918-711869_9059761522.3333333333333Compositional biasNote=Asp/Glu-rich
HgeneSUGP2chr19:19114977chr5:1318568ENST00000601879-710738_7769761083.0Compositional biasNote=Pro/Ser-rich
HgeneSUGP2chr19:19114977chr5:1318568ENST00000601879-710869_9059761083.0Compositional biasNote=Asp/Glu-rich
HgeneSUGP2chr19:19114977chr5:1318568ENST00000337018-711590_6339761124.0RepeatNote=SURP motif 1
HgeneSUGP2chr19:19114977chr5:1318568ENST00000337018-711787_8309761124.0RepeatNote=SURP motif 2
HgeneSUGP2chr19:19114977chr5:1318568ENST00000452918-711590_6339761522.3333333333333RepeatNote=SURP motif 1
HgeneSUGP2chr19:19114977chr5:1318568ENST00000452918-711787_8309761522.3333333333333RepeatNote=SURP motif 2
HgeneSUGP2chr19:19114977chr5:1318568ENST00000601879-710590_6339761083.0RepeatNote=SURP motif 1
HgeneSUGP2chr19:19114977chr5:1318568ENST00000601879-710787_8309761083.0RepeatNote=SURP motif 2

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneSUGP2chr19:19114977chr5:1318568ENST00000337018-7111011_10579761124.0DomainG-patch
HgeneSUGP2chr19:19114977chr5:1318568ENST00000452918-7111011_10579761522.3333333333333DomainG-patch
HgeneSUGP2chr19:19114977chr5:1318568ENST00000601879-7101011_10579761083.0DomainG-patch
HgeneSUGP2chr19:19114977chr5:1318568ENST00000337018-711995_10009761124.0MotifNuclear localization signal
HgeneSUGP2chr19:19114977chr5:1318568ENST00000452918-711995_10009761522.3333333333333MotifNuclear localization signal
HgeneSUGP2chr19:19114977chr5:1318568ENST00000601879-710995_10009761083.0MotifNuclear localization signal
TgeneCLPTM1Lchr19:19114977chr5:1318568ENST0000032089515171_10510539.0Topological domainCytoplasmic
TgeneCLPTM1Lchr19:19114977chr5:1318568ENST000003208951517306_324510539.0Topological domainCytoplasmic
TgeneCLPTM1Lchr19:19114977chr5:1318568ENST00000320895151732_284510539.0Topological domainExtracellular
TgeneCLPTM1Lchr19:19114977chr5:1318568ENST000003208951517343_346510539.0Topological domainExtracellular
TgeneCLPTM1Lchr19:19114977chr5:1318568ENST000003208951517365_402510539.0Topological domainCytoplasmic
TgeneCLPTM1Lchr19:19114977chr5:1318568ENST000003208951517424_428510539.0Topological domainExtracellular
TgeneCLPTM1Lchr19:19114977chr5:1318568ENST000003208951517450_538510539.0Topological domainCytoplasmic
TgeneCLPTM1Lchr19:19114977chr5:1318568ENST0000032092714161_10474503.0Topological domainCytoplasmic
TgeneCLPTM1Lchr19:19114977chr5:1318568ENST000003209271416306_324474503.0Topological domainCytoplasmic
TgeneCLPTM1Lchr19:19114977chr5:1318568ENST00000320927141632_284474503.0Topological domainExtracellular
TgeneCLPTM1Lchr19:19114977chr5:1318568ENST000003209271416343_346474503.0Topological domainExtracellular
TgeneCLPTM1Lchr19:19114977chr5:1318568ENST000003209271416365_402474503.0Topological domainCytoplasmic
TgeneCLPTM1Lchr19:19114977chr5:1318568ENST000003209271416424_428474503.0Topological domainExtracellular
TgeneCLPTM1Lchr19:19114977chr5:1318568ENST000003209271416450_538474503.0Topological domainCytoplasmic
TgeneCLPTM1Lchr19:19114977chr5:1318568ENST00000320895151711_31510539.0TransmembraneHelical
TgeneCLPTM1Lchr19:19114977chr5:1318568ENST000003208951517285_305510539.0TransmembraneHelical
TgeneCLPTM1Lchr19:19114977chr5:1318568ENST000003208951517325_342510539.0TransmembraneHelical
TgeneCLPTM1Lchr19:19114977chr5:1318568ENST000003208951517347_364510539.0TransmembraneHelical
TgeneCLPTM1Lchr19:19114977chr5:1318568ENST000003208951517403_423510539.0TransmembraneHelical
TgeneCLPTM1Lchr19:19114977chr5:1318568ENST000003208951517429_449510539.0TransmembraneHelical
TgeneCLPTM1Lchr19:19114977chr5:1318568ENST00000320927141611_31474503.0TransmembraneHelical
TgeneCLPTM1Lchr19:19114977chr5:1318568ENST000003209271416285_305474503.0TransmembraneHelical
TgeneCLPTM1Lchr19:19114977chr5:1318568ENST000003209271416325_342474503.0TransmembraneHelical
TgeneCLPTM1Lchr19:19114977chr5:1318568ENST000003209271416347_364474503.0TransmembraneHelical
TgeneCLPTM1Lchr19:19114977chr5:1318568ENST000003209271416403_423474503.0TransmembraneHelical
TgeneCLPTM1Lchr19:19114977chr5:1318568ENST000003209271416429_449474503.0TransmembraneHelical


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Fusion Gene Sequence for SUGP2-CLPTM1L


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>88002_88002_1_SUGP2-CLPTM1L_SUGP2_chr19_19114977_ENST00000337018_CLPTM1L_chr5_1318568_ENST00000507807_length(transcript)=3764nt_BP=3063nt
CTGCGCGGCGCGGCGCTGCGGAGACCGTTGGTTCATTTGCATGTCCCCGCCTCGCGCGGCGGCGGCGGCGGGTGAGGAGCCTGAGGCGGC
GGCGGGGGTGGCTCCGCGCGCGGTGGTCTCGGGGGCAAAATAACATGGCAGCCAGACGAATTACACAGGAGACTTTTGATGCTGTATTAC
AAGAAAAAGCCAAACGATATCACATGGATGCCAGTGGTGAGGCTGTAAGCGAAACTCTTCAGTTTAAAGCTCAAGATCTCTTAAGGGCAG
TCCCAAGATCCAGAGCAGAGATGTATGATGACGTCCACAGCGATGGCAGATACTCCCTCAGTGGATCTGTAGCTCACTCTAGAGATGCCG
GAAGAGAAGGCCTGAGAAGTGACGTATTTCCAGGGCCTTCCTTCAGATCAAGCAACCCTTCCATCAGTGATGACAGCTACTTTCGCAAAG
AATGTGGCCGGGATCTGGAATTTTCTCACTCTGATTCTCGGGACCAGGTCATTGGCCACCGGAAATTGGGGCATTTCCGTTCTCAGGACT
GGAAATTTGCGCTCCGTGGTTCTTGGGAACAAGACTTTGGCCATCCAGTTTCTCAAGAGTCCTCTTGGTCACAGGAGTATAGTTTTGGTC
CCTCTGCAGTTTTGGGGGACTTTGGATCTTCCAGGCTGATTGAGAAAGAGTGTTTGGAGAAGGAGAGTCGGGATTATGACGTGGACCATC
CTGGGGAGGCTGACTCTGTGCTTAGGGGCGGCAGTCAAGTCCAGGCCAGAGGTCGAGCTCTAAACATCGTTGACCAGGAAGGTTCCCTCC
TAGGAAAGGGGGAGACTCAGGGCCTGCTCACAGCTAAGGGGGGTGTTGGGAAACTTGTCACATTGAGAAATGTGAGCACAAAAAAAATAC
CCACCGTGAATCGTATTACTCCCAAAACTCAGGGCACTAACCAAATCCAGAAAAACACTCCAAGTCCTGATGTGACCCTGGGGACAAACC
CAGGGACAGAAGATATCCAGTTCCCCATTCAGAAGATCCCTCTGGGGCTGGATCTGAAGAATCTTCGGCTCCCCAGAAGAAAGATGAGCT
TTGACATCATAGATAAGTCTGATGTTTTTTCAAGATTTGGGATAGAAATAATCAAATGGGCAGGATTCCACACCATAAAAGATGATATTA
AATTTTCCCAACTTTTCCAGACTCTCTTTGAACTTGAAACAGAAACCTGTGCTAAAATGCTTGCCTCATTCAAATGTTCCTTAAAACCAG
AGCACAGAGATTTTTGCTTTTTTACTATCAAATTTTTAAAGCACTCTGCTTTGAAAACACCCAGAGTTGATAATGAGTTTTTAAACATGC
TTTTAGACAAAGGTGCTGTGAAGACCAAAAATTGCTTTTTTGAAATCATAAAGCCTTTTGACAAGTACATAATGAGACTTCAAGACCGGC
TTCTGAAGAGTGTCACACCTTTGCTTATGGCCTGCAATGCCTACGAGCTAAGTGTCAAGATGAAGACCCTCAGTAACCCCCTGGACTTGG
CTCTTGCCCTAGAAACCACCAACTCTCTCTGCCGGAAGTCTTTGGCCCTTTTGGGACAGACATTTTCCTTGGCCTCTTCTTTCCGGCAGG
AGAAAATCTTAGAAGCTGTCGGCCTGCAAGATATAGCTCCCTCACCTGCTGCGTTTCCAAACTTCGAAGACTCCACTTTGTTTGGGCGAG
AGTACATAGACCACCTGAAGGCCTGGCTAGTCAGCAGCGGATGTCCCCTCCAGGTTAAGAAAGCCGAACCAGAGCCGATGCGAGAGGAGG
AGAAAATGATTCCTCCTACGAAACCTGAAATTCAGGCCAAGGCTCCAAGTAGTCTGAGTGATGCTGTCCCCCAGCGAGCAGATCACAGGG
TAGTGGGCACCATCGACCAGCTTGTGAAACGTGTCATCGAAGGCAGCCTGTCTCCCAAAGAGAGAACTCTTCTCAAAGAGGACCCTGCTT
ACTGGTTTTTGTCTGATGAAAATAGTCTGGAGTATAAATATTACAAGCTGAAGTTGGCAGAAATGCAGCGGATGAGCGAGAACTTGCGAG
GAGCCGACCAGAAGCCGACCTCAGCAGACTGTGCAGTGAGGGCCATGCTGTACTCCCGGGCTGTCCGCAACCTCAAGAAGAAACTCCTTC
CGTGGCAGCGGCGGGGGCTCCTCCGTGCTCAAGGGCTCCGGGGCTGGAAGGCGAGGAGAGCGACCACCGGGACCCAGACCCTCCTATCCT
CAGGCACCAGGCTGAAACACCACGGCCGGCAGGCTCCAGGCCTCTCACAGGCAAAACCATCCCTGCCAGACAGAAATGATGCTGCCAAGG
ACTGCCCGCCAGACCCAGTTGGACCTTCTCCTCAGGACCCCAGCTTAGAAGCCTCAGGCCCATCCCCCAAGCCAGCAGGAGTGGACATCT
CTGAAGCACCTCAGACCTCTTCTCCCTGCCCATCTGCTGACATTGACATGAAGACAATGGAGACTGCAGAGAAACTGGCTAGATTTGTTG
CTCAGGTGGGACCAGAGATCGAACAATTCAGCATAGAAAACAGCACCGATAACCCTGACCTGTGGTTTCTACATGACCAAAATAGTTCTG
CTTTCAAATTCTATCGAAAGAAAGTGTTTGAACTATGTCCATCAATTTGTTTCACGTCATCTCCGCACAACCTTCACACTGGTGGTGGTG
ACACCACGGGTTCTCAGGAGAGCCCCGTGGACCTCATGGAAGGGGAAGCAGAGTTTGAAGACGAGCCCCCTCCGCGGGAGGCTGAGCTGG
AGAGCCCAGAGGTGATGCCTGAGGAGGAGGACGAGGACGATGAGGATGGGGGAGAGGAGGCCCCCGCTCCTGGAGGGGCGGGCAAGTCTG
AGGGCAGCACCCCTGCCGACGGCCTTCCCGGCGAGGCTGCCGAGGACGACCTGGCTGGAGCACCTGCCTTGTCACAGGCCTCCTCAGGTA
CCTGCTTCCCTCGGAAGAGGATCAGCAGCAAGTCATTGAAGGTTGGCATGATTCCAGCTCCCAAGAGAGTGTGTCTCATCCAGGAGCCAA
AAGGCTTTATCCTGTGGATAAACGCAGAGTGAACGAGTTTGGGGAGTCCTACGAGGAGAAGGCCACGCGGGCGCCCCACACGGACTGAAG
GCCGCCCGGGCTGCCGCCAGCCAAGTGCAACTTGAATTGTCAATGAGTATTTTTGGAAGCATTTGGAGGAATTCCTAGACATTGCGTTTT
CTGTGTTGCCAAAATCCCTTCGGACATTTCTCAGACATCTCCCAAGTTCCCATCACGTCAGATTTGGAGCTGGTAGCGCTTACGATGCCC
CCACGTGTGAACATCTGTCTTGGTCACAGAGCTGGGTGCTGCCGGTCACCTTGAGCTGTGGTGGCTCCCGGCACACGAGTGTCCGGGGTT
CGGCCATGTCCTCACGCGGGCAGGGGTGGGAGCCCTCACAGGCAAGGGGGCTGTTGGATTTCCATTTCAGGTGGTTTTCTAAGTGCTCCT
TATGTGAATTTCAAACACGTATGGAATTCATTCCGCATGGACTCTGGGATCAAAGGCTCTTTCCTCTTTTGTTTGAGAGTTGGTTGTTTT
AAAGCTTAATGTATGTTTCTATTTTAAAATAAATTTTTCTGGCTGTGGCATTTTTCTTGACCTGGTATAATGAAAGTATTTCGGATATTT

>88002_88002_1_SUGP2-CLPTM1L_SUGP2_chr19_19114977_ENST00000337018_CLPTM1L_chr5_1318568_ENST00000507807_length(amino acids)=1003AA_BP=
MRRRRGWLRARWSRGQNNMAARRITQETFDAVLQEKAKRYHMDASGEAVSETLQFKAQDLLRAVPRSRAEMYDDVHSDGRYSLSGSVAHS
RDAGREGLRSDVFPGPSFRSSNPSISDDSYFRKECGRDLEFSHSDSRDQVIGHRKLGHFRSQDWKFALRGSWEQDFGHPVSQESSWSQEY
SFGPSAVLGDFGSSRLIEKECLEKESRDYDVDHPGEADSVLRGGSQVQARGRALNIVDQEGSLLGKGETQGLLTAKGGVGKLVTLRNVST
KKIPTVNRITPKTQGTNQIQKNTPSPDVTLGTNPGTEDIQFPIQKIPLGLDLKNLRLPRRKMSFDIIDKSDVFSRFGIEIIKWAGFHTIK
DDIKFSQLFQTLFELETETCAKMLASFKCSLKPEHRDFCFFTIKFLKHSALKTPRVDNEFLNMLLDKGAVKTKNCFFEIIKPFDKYIMRL
QDRLLKSVTPLLMACNAYELSVKMKTLSNPLDLALALETTNSLCRKSLALLGQTFSLASSFRQEKILEAVGLQDIAPSPAAFPNFEDSTL
FGREYIDHLKAWLVSSGCPLQVKKAEPEPMREEEKMIPPTKPEIQAKAPSSLSDAVPQRADHRVVGTIDQLVKRVIEGSLSPKERTLLKE
DPAYWFLSDENSLEYKYYKLKLAEMQRMSENLRGADQKPTSADCAVRAMLYSRAVRNLKKKLLPWQRRGLLRAQGLRGWKARRATTGTQT
LLSSGTRLKHHGRQAPGLSQAKPSLPDRNDAAKDCPPDPVGPSPQDPSLEASGPSPKPAGVDISEAPQTSSPCPSADIDMKTMETAEKLA
RFVAQVGPEIEQFSIENSTDNPDLWFLHDQNSSAFKFYRKKVFELCPSICFTSSPHNLHTGGGDTTGSQESPVDLMEGEAEFEDEPPPRE
AELESPEVMPEEEDEDDEDGGEEAPAPGGAGKSEGSTPADGLPGEAAEDDLAGAPALSQASSGTCFPRKRISSKSLKVGMIPAPKRVCLI

--------------------------------------------------------------
>88002_88002_2_SUGP2-CLPTM1L_SUGP2_chr19_19114977_ENST00000452918_CLPTM1L_chr5_1318568_ENST00000507807_length(transcript)=3704nt_BP=3003nt
GGCGGCGGCGGGTGAGGAGCCTGAGGCGGCGGCGGGGGTGGCTCCGCGCGCGGTGGTCTCGGGGGCAAAATAACATGGCAGCCAGACGAA
TTACACAGGAGACTTTTGATGCTGTATTACAAGAAAAAGCCAAACGATATCACATGGATGCCAGTGGTGAGGCTGTAAGCGAAACTCTTC
AGTTTAAAGCTCAAGATCTCTTAAGGGCAGTCCCAAGATCCAGAGCAGAGATGTATGATGACGTCCACAGCGATGGCAGATACTCCCTCA
GTGGATCTGTAGCTCACTCTAGAGATGCCGGAAGAGAAGGCCTGAGAAGTGACGTATTTCCAGGGCCTTCCTTCAGATCAAGCAACCCTT
CCATCAGTGATGACAGCTACTTTCGCAAAGAATGTGGCCGGGATCTGGAATTTTCTCACTCTGATTCTCGGGACCAGGTCATTGGCCACC
GGAAATTGGGGCATTTCCGTTCTCAGGACTGGAAATTTGCGCTCCGTGGTTCTTGGGAACAAGACTTTGGCCATCCAGTTTCTCAAGAGT
CCTCTTGGTCACAGGAGTATAGTTTTGGTCCCTCTGCAGTTTTGGGGGACTTTGGATCTTCCAGGCTGATTGAGAAAGAGTGTTTGGAGA
AGGAGAGTCGGGATTATGACGTGGACCATCCTGGGGAGGCTGACTCTGTGCTTAGGGGCGGCAGTCAAGTCCAGGCCAGAGGTCGAGCTC
TAAACATCGTTGACCAGGAAGGTTCCCTCCTAGGAAAGGGGGAGACTCAGGGCCTGCTCACAGCTAAGGGGGGTGTTGGGAAACTTGTCA
CATTGAGAAATGTGAGCACAAAAAAAATACCCACCGTGAATCGTATTACTCCCAAAACTCAGGGCACTAACCAAATCCAGAAAAACACTC
CAAGTCCTGATGTGACCCTGGGGACAAACCCAGGGACAGAAGATATCCAGTTCCCCATTCAGAAGATCCCTCTGGGGCTGGATCTGAAGA
ATCTTCGGCTCCCCAGAAGAAAGATGAGCTTTGACATCATAGATAAGTCTGATGTTTTTTCAAGATTTGGGATAGAAATAATCAAATGGG
CAGGATTCCACACCATAAAAGATGATATTAAATTTTCCCAACTTTTCCAGACTCTCTTTGAACTTGAAACAGAAACCTGTGCTAAAATGC
TTGCCTCATTCAAATGTTCCTTAAAACCAGAGCACAGAGATTTTTGCTTTTTTACTATCAAATTTTTAAAGCACTCTGCTTTGAAAACAC
CCAGAGTTGATAATGAGTTTTTAAACATGCTTTTAGACAAAGGTGCTGTGAAGACCAAAAATTGCTTTTTTGAAATCATAAAGCCTTTTG
ACAAGTACATAATGAGACTTCAAGACCGGCTTCTGAAGAGTGTCACACCTTTGCTTATGGCCTGCAATGCCTACGAGCTAAGTGTCAAGA
TGAAGACCCTCAGTAACCCCCTGGACTTGGCTCTTGCCCTAGAAACCACCAACTCTCTCTGCCGGAAGTCTTTGGCCCTTTTGGGACAGA
CATTTTCCTTGGCCTCTTCTTTCCGGCAGGAGAAAATCTTAGAAGCTGTCGGCCTGCAAGATATAGCTCCCTCACCTGCTGCGTTTCCAA
ACTTCGAAGACTCCACTTTGTTTGGGCGAGAGTACATAGACCACCTGAAGGCCTGGCTAGTCAGCAGCGGATGTCCCCTCCAGGTTAAGA
AAGCCGAACCAGAGCCGATGCGAGAGGAGGAGAAAATGATTCCTCCTACGAAACCTGAAATTCAGGCCAAGGCTCCAAGTAGTCTGAGTG
ATGCTGTCCCCCAGCGAGCAGATCACAGGGTAGTGGGCACCATCGACCAGCTTGTGAAACGTGTCATCGAAGGCAGCCTGTCTCCCAAAG
AGAGAACTCTTCTCAAAGAGGACCCTGCTTACTGGTTTTTGTCTGATGAAAATAGTCTGGAGTATAAATATTACAAGCTGAAGTTGGCAG
AAATGCAGCGGATGAGCGAGAACTTGCGAGGAGCCGACCAGAAGCCGACCTCAGCAGACTGTGCAGTGAGGGCCATGCTGTACTCCCGGG
CTGTCCGCAACCTCAAGAAGAAACTCCTTCCGTGGCAGCGGCGGGGGCTCCTCCGTGCTCAAGGGCTCCGGGGCTGGAAGGCGAGGAGAG
CGACCACCGGGACCCAGACCCTCCTATCCTCAGGCACCAGGCTGAAACACCACGGCCGGCAGGCTCCAGGCCTCTCACAGGCAAAACCAT
CCCTGCCAGACAGAAATGATGCTGCCAAGGACTGCCCGCCAGACCCAGTTGGACCTTCTCCTCAGGACCCCAGCTTAGAAGCCTCAGGCC
CATCCCCCAAGCCAGCAGGAGTGGACATCTCTGAAGCACCTCAGACCTCTTCTCCCTGCCCATCTGCTGACATTGACATGAAGACAATGG
AGACTGCAGAGAAACTGGCTAGATTTGTTGCTCAGGTGGGACCAGAGATCGAACAATTCAGCATAGAAAACAGCACCGATAACCCTGACC
TGTGGTTTCTACATGACCAAAATAGTTCTGCTTTCAAATTCTATCGAAAGAAAGTGTTTGAACTATGTCCATCAATTTGTTTCACGTCAT
CTCCGCACAACCTTCACACTGGTGGTGGTGACACCACGGGTTCTCAGGAGAGCCCCGTGGACCTCATGGAAGGGGAAGCAGAGTTTGAAG
ACGAGCCCCCTCCGCGGGAGGCTGAGCTGGAGAGCCCAGAGGTGATGCCTGAGGAGGAGGACGAGGACGATGAGGATGGGGGAGAGGAGG
CCCCCGCTCCTGGAGGGGCGGGCAAGTCTGAGGGCAGCACCCCTGCCGACGGCCTTCCCGGCGAGGCTGCCGAGGACGACCTGGCTGGAG
CACCTGCCTTGTCACAGGCCTCCTCAGGTACCTGCTTCCCTCGGAAGAGGATCAGCAGCAAGTCATTGAAGGTTGGCATGATTCCAGCTC
CCAAGAGAGTGTGTCTCATCCAGGAGCCAAAAGGCTTTATCCTGTGGATAAACGCAGAGTGAACGAGTTTGGGGAGTCCTACGAGGAGAA
GGCCACGCGGGCGCCCCACACGGACTGAAGGCCGCCCGGGCTGCCGCCAGCCAAGTGCAACTTGAATTGTCAATGAGTATTTTTGGAAGC
ATTTGGAGGAATTCCTAGACATTGCGTTTTCTGTGTTGCCAAAATCCCTTCGGACATTTCTCAGACATCTCCCAAGTTCCCATCACGTCA
GATTTGGAGCTGGTAGCGCTTACGATGCCCCCACGTGTGAACATCTGTCTTGGTCACAGAGCTGGGTGCTGCCGGTCACCTTGAGCTGTG
GTGGCTCCCGGCACACGAGTGTCCGGGGTTCGGCCATGTCCTCACGCGGGCAGGGGTGGGAGCCCTCACAGGCAAGGGGGCTGTTGGATT
TCCATTTCAGGTGGTTTTCTAAGTGCTCCTTATGTGAATTTCAAACACGTATGGAATTCATTCCGCATGGACTCTGGGATCAAAGGCTCT
TTCCTCTTTTGTTTGAGAGTTGGTTGTTTTAAAGCTTAATGTATGTTTCTATTTTAAAATAAATTTTTCTGGCTGTGGCATTTTTCTTGA
CCTGGTATAATGAAAGTATTTCGGATATTTGAGTTTAACCCTTTTCCAGAAAGTAATACATGATATGGATTTATTTATGCATTAAAAGAG

>88002_88002_2_SUGP2-CLPTM1L_SUGP2_chr19_19114977_ENST00000452918_CLPTM1L_chr5_1318568_ENST00000507807_length(amino acids)=1003AA_BP=
MRRRRGWLRARWSRGQNNMAARRITQETFDAVLQEKAKRYHMDASGEAVSETLQFKAQDLLRAVPRSRAEMYDDVHSDGRYSLSGSVAHS
RDAGREGLRSDVFPGPSFRSSNPSISDDSYFRKECGRDLEFSHSDSRDQVIGHRKLGHFRSQDWKFALRGSWEQDFGHPVSQESSWSQEY
SFGPSAVLGDFGSSRLIEKECLEKESRDYDVDHPGEADSVLRGGSQVQARGRALNIVDQEGSLLGKGETQGLLTAKGGVGKLVTLRNVST
KKIPTVNRITPKTQGTNQIQKNTPSPDVTLGTNPGTEDIQFPIQKIPLGLDLKNLRLPRRKMSFDIIDKSDVFSRFGIEIIKWAGFHTIK
DDIKFSQLFQTLFELETETCAKMLASFKCSLKPEHRDFCFFTIKFLKHSALKTPRVDNEFLNMLLDKGAVKTKNCFFEIIKPFDKYIMRL
QDRLLKSVTPLLMACNAYELSVKMKTLSNPLDLALALETTNSLCRKSLALLGQTFSLASSFRQEKILEAVGLQDIAPSPAAFPNFEDSTL
FGREYIDHLKAWLVSSGCPLQVKKAEPEPMREEEKMIPPTKPEIQAKAPSSLSDAVPQRADHRVVGTIDQLVKRVIEGSLSPKERTLLKE
DPAYWFLSDENSLEYKYYKLKLAEMQRMSENLRGADQKPTSADCAVRAMLYSRAVRNLKKKLLPWQRRGLLRAQGLRGWKARRATTGTQT
LLSSGTRLKHHGRQAPGLSQAKPSLPDRNDAAKDCPPDPVGPSPQDPSLEASGPSPKPAGVDISEAPQTSSPCPSADIDMKTMETAEKLA
RFVAQVGPEIEQFSIENSTDNPDLWFLHDQNSSAFKFYRKKVFELCPSICFTSSPHNLHTGGGDTTGSQESPVDLMEGEAEFEDEPPPRE
AELESPEVMPEEEDEDDEDGGEEAPAPGGAGKSEGSTPADGLPGEAAEDDLAGAPALSQASSGTCFPRKRISSKSLKVGMIPAPKRVCLI

--------------------------------------------------------------
>88002_88002_3_SUGP2-CLPTM1L_SUGP2_chr19_19114977_ENST00000456085_CLPTM1L_chr5_1318568_ENST00000320895_length(transcript)=3200nt_BP=2490nt
ATTACAAGAAAAAGCCAAACGATATCACATGGATGCCAGTGGTGAGGCTGTAAGCGAAACTCTTCAGTTTAAAGCTCAAGATCTCTTAAG
GGCAGTCCCAAGATCCAGAGCAGAGATGTATGATGACGTCCACAGCGATGGCAGATACTCCCTCAGTGGATCTGTAGCTCACTCTAGAGA
TGCCGGAAGAGAAGGCCTGAGAAGTGACGTATTTCCAGGGCCTTCCTTCAGATCAAGCAACCCTTCCATCAGTGATGACAGCTACTTTCG
CAAAGAATGTGGCCGGGATCTGGAATTTTCTCACTCTGATTCTCGGGACCAGGTCATTGGCCACCGGAAATTGGGGCATTTCCGTTCTCA
GGACTGGAAATTTGCGCTCCGTGGTTCTTGGGAACAAGACTTTGGCCATCCAGTTTCTCAAGAGTCCTCTTGGTCACAGGAGTATAGTTT
TGATCCCTCTGGGGCTGGATCTGAAGAATCTTCGGCTCCCCAGAAGAAAGATGAGCTTTGACATCATAGATAAGTCTGATGTTTTTTCAA
GATTTGGGATAGAAATAATCAAATGGGCAGGATTCCACACCATAAAAGATGATATTAAATTTTCCCAACTTTTCCAGACTCTCTTTGAAC
TTGAAACAGAAACCTGTGCTAAAATGCTTGCCTCATTCAAATGTTCCTTAAAACCAGAGCACAGAGATTTTTGCTTTTTTACTATCAAAT
TTTTAAAGCACTCTGCTTTGAAAACACCCAGAGTTGATAATGAGTTTTTAAACATGCTTTTAGACAAAGGTGCTGTGAAGACCAAAAATT
GCTTTTTTGAAATCATAAAGCCTTTTGACAAGTACATAATGAGACTTCAAGACCGGCTTCTGAAGAGTGTCACACCTTTGCTTATGGCCT
GCAATGCCTACGAGCTAAGTGTCAAGATGAAGACCCTCAGTAACCCCCTGGACTTGGCTCTTGCCCTAGAAACCACCAACTCTCTCTGCC
GGAAGTCTTTGGCCCTTTTGGGACAGACATTTTCCTTGGCCTCTTCTTTCCGGCAGGAGAAAATCTTAGAAGCTGTCGGCCTGCAAGATA
TAGCTCCCTCACCTGCTGCGTTTCCAAACTTCGAAGACTCCACTTTGTTTGGGCGAGAGTACATAGACCACCTGAAGGCCTGGCTAGTCA
GCAGCGGATGTCCCCTCCAGGTTAAGAAAGCCGAACCAGAGCCGATGCGAGAGGAGGAGAAAATGATTCCTCCTACGAAACCTGAAATTC
AGGCCAAGGCTCCAAGTAGTCTGAGTGATGCTGTCCCCCAGCGAGCAGATCACAGGGTAGTGGGCACCATCGACCAGCTTGTGAAACGTG
TCATCGAAGGCAGCCTGTCTCCCAAAGAGAGAACTCTTCTCAAAGAGGACCCTGCTTACTGGTTTTTGTCTGATGAAAATAGTCTGGAGT
ATAAATATTACAAGCTGAAGTTGGCAGAAATGCAGCGGATGAGCGAGAACTTGCGAGGAGCCGACCAGAAGCCGACCTCAGCAGACTGTG
CAGTGAGGGCCATGCTGTACTCCCGGGCTGTCCGCAACCTCAAGAAGAAACTCCTTCCGTGGCAGCGGCGGGGGCTCCTCCGTGCTCAAG
GGCTCCGGGGCTGGAAGGCGAGGAGAGCGACCACCGGGACCCAGACCCTCCTATCCTCAGGCACCAGGCTGAAACACCACGGCCGGCAGG
CTCCAGGCCTCTCACAGGCAAAACCATCCCTGCCAGACAGAAATGATGCTGCCAAGGACTGCCCGCCAGACCCAGTTGGACCTTCTCCTC
AGGACCCCAGCTTAGAAGCCTCAGGCCCATCCCCCAAGCCAGCAGGAGTGGACATCTCTGAAGCACCTCAGACCTCTTCTCCCTGCCCAT
CTGCTGACATTGACATGAAGACAATGGAGACTGCAGAGAAACTGGCTAGATTTGTTGCTCAGGTGGGACCAGAGATCGAACAATTCAGCA
TAGAAAACAGCACCGATAACCCTGACCTGTGGTTTCTACATGACCAAAATAGTTCTGCTTTCAAATTCTATCGAAAGAAAGTGTTTGAAC
TATGTCCATCAATTTGTTTCACGTCATCTCCGCACAACCTTCACACTGGTGGTGGTGACACCACGGGTTCTCAGGAGAGCCCCGTGGACC
TCATGGAAGGGGAAGCAGAGTTTGAAGACGAGCCCCCTCCGCGGGAGGCTGAGCTGGAGAGCCCAGAGGTGATGCCTGAGGAGGAGGACG
AGGACGATGAGGATGGGGGAGAGGAGGCCCCCGCTCCTGGAGGGGCGGGCAAGTCTGAGGGCAGCACCCCTGCCGACGGCCTTCCCGGCG
AGGCTGCCGAGGACGACCTGGCTGGAGCACCTGCCTTGTCACAGGCCTCCTCAGGTACCTGCTTCCCTCGGAAGAGGATCAGCAGCAAGT
CATTGAAGGTTGGCATGATTCCAGCTCCCAAGAGAGTGTGTCTCATCCAGGAGCCAAAAGGCTTTATCCTGTGGATAAACGCAGAGTGAA
CGAGTTTGGGGAGTCCTACGAGGAGAAGGCCACGCGGGCGCCCCACACGGACTGAAGGCCGCCCGGGCTGCCGCCAGCCAAGTGCAACTT
GAATTGTCAATGAGTATTTTTGGAAGCATTTGGAGGAATTCCTAGACATTGCGTTTTCTGTGTTGCCAAAATCCCTTCGGACATTTCTCA
GACATCTCCCAAGTTCCCATCACGTCAGATTTGGAGCTGGTAGCGCTTACGATGCCCCCACGTGTGAACATCTGTCTTGGTCACAGAGCT
GGGTGCTGCCGGTCACCTTGAGCTGTGGTGGCTCCCGGCACACGAGTGTCCGGGGTTCGGCCATGTCCTCACGCGGGCAGGGGTGGGAGC
CCTCACAGGCAAGGGGGCTGTTGGATTTCCATTTCAGGTGGTTTTCTAAGTGCTCCTTATGTGAATTTCAAACACGTATGGAATTCATTC
CGCATGGACTCTGGGATCAAAGGCTCTTTCCTCTTTTGTTTGAGAGTTGGTTGTTTTAAAGCTTAATGTATGTTTCTATTTTAAAATAAA
TTTTTCTGGCTGTGGCATTTTTCTTGACCTGGTATAATGAAAGTATTTCGGATATTTGAGTTTAACCCTTTTCCAGAAAGTAATACATGA

>88002_88002_3_SUGP2-CLPTM1L_SUGP2_chr19_19114977_ENST00000456085_CLPTM1L_chr5_1318568_ENST00000320895_length(amino acids)=754AA_BP=
MTATFAKNVAGIWNFLTLILGTRSLATGNWGISVLRTGNLRSVVLGNKTLAIQFLKSPLGHRSIVLIPLGLDLKNLRLPRRKMSFDIIDK
SDVFSRFGIEIIKWAGFHTIKDDIKFSQLFQTLFELETETCAKMLASFKCSLKPEHRDFCFFTIKFLKHSALKTPRVDNEFLNMLLDKGA
VKTKNCFFEIIKPFDKYIMRLQDRLLKSVTPLLMACNAYELSVKMKTLSNPLDLALALETTNSLCRKSLALLGQTFSLASSFRQEKILEA
VGLQDIAPSPAAFPNFEDSTLFGREYIDHLKAWLVSSGCPLQVKKAEPEPMREEEKMIPPTKPEIQAKAPSSLSDAVPQRADHRVVGTID
QLVKRVIEGSLSPKERTLLKEDPAYWFLSDENSLEYKYYKLKLAEMQRMSENLRGADQKPTSADCAVRAMLYSRAVRNLKKKLLPWQRRG
LLRAQGLRGWKARRATTGTQTLLSSGTRLKHHGRQAPGLSQAKPSLPDRNDAAKDCPPDPVGPSPQDPSLEASGPSPKPAGVDISEAPQT
SSPCPSADIDMKTMETAEKLARFVAQVGPEIEQFSIENSTDNPDLWFLHDQNSSAFKFYRKKVFELCPSICFTSSPHNLHTGGGDTTGSQ
ESPVDLMEGEAEFEDEPPPREAELESPEVMPEEEDEDDEDGGEEAPAPGGAGKSEGSTPADGLPGEAAEDDLAGAPALSQASSGTCFPRK

--------------------------------------------------------------
>88002_88002_4_SUGP2-CLPTM1L_SUGP2_chr19_19114977_ENST00000600377_CLPTM1L_chr5_1318568_ENST00000320927_length(transcript)=3577nt_BP=2991nt
GAGACCGTTGGTTCATTTGCATGTCCCCGCCTCGCGCGGCGGCGGCGGCGGGGCAAAATAACATGGCAGCCAGACGAATTACACAGGAGA
CTTTTGATGCTGTATTACAAGAAAAAGCCAAACGATATCACATGGATGCCAGTGGTGAGGCTGTAAGCGAAACTCTTCAGTTTAAAGCTC
AAGATCTCTTAAGGGCAGTCCCAAGATCCAGAGCAGAGATGTATGATGACGTCCACAGCGATGGCAGATACTCCCTCAGTGGATCTGTAG
CTCACTCTAGAGATGCCGGAAGAGAAGGCCTGAGAAGTGACGTATTTCCAGGGCCTTCCTTCAGATCAAGCAACCCTTCCATCAGTGATG
ACAGCTACTTTCGCAAAGAATGTGGCCGGGATCTGGAATTTTCTCACTCTGATTCTCGGGACCAGGTCATTGGCCACCGGAAATTGGGGC
ATTTCCGTTCTCAGGACTGGAAATTTGCGCTCCGTGGTTCTTGGGAACAAGACTTTGGCCATCCAGTTTCTCAAGAGTCCTCTTGGTCAC
AGGAGTATAGTTTTGGTCCCTCTGCAGTTTTGGGGGACTTTGGATCTTCCAGGCTGATTGAGAAAGAGTGTTTGGAGAAGGAGAGTCGGG
ATTATGACGTGGACCATCCTGGGGAGGCTGACTCTGTGCTTAGGGGCGGCAGTCAAGTCCAGGCCAGAGGTCGAGCTCTAAACATCGTTG
ACCAGGAAGGTTCCCTCCTAGGAAAGGGGGAGACTCAGGGCCTGCTCACAGCTAAGGGGGGTGTTGGGAAACTTGTCACATTGAGAAATG
TGAGCACAAAAAAAATACCCACCGTGAATCGTATTACTCCCAAAACTCAGGGCACTAACCAAATCCAGAAAAACACTCCAAGTCCTGATG
TGACCCTGGGGACAAACCCAGGGACAGAAGATATCCAGTTCCCCATTCAGAAGATCCCTCTGGGGCTGGATCTGAAGAATCTTCGGCTCC
CCAGAAGAAAGATGAGCTTTGACATCATAGATAAGTCTGATGTTTTTTCAAGATTTGGGATAGAAATAATCAAATGGGCAGGATTCCACA
CCATAAAAGATGATATTAAATTTTCCCAACTTTTCCAGACTCTCTTTGAACTTGAAACAGAAACCTGTGCTAAAATGCTTGCCTCATTCA
AATGTTCCTTAAAACCAGAGCACAGAGATTTTTGCTTTTTTACTATCAAATTTTTAAAGCACTCTGCTTTGAAAACACCCAGAGTTGATA
ATGAGTTTTTAAACATGCTTTTAGACAAAGGTGCTGTGAAGACCAAAAATTGCTTTTTTGAAATCATAAAGCCTTTTGACAAGTACATAA
TGAGACTTCAAGACCGGCTTCTGAAGAGTGTCACACCTTTGCTTATGGCCTGCAATGCCTACGAGCTAAGTGTCAAGATGAAGACCCTCA
GTAACCCCCTGGACTTGGCTCTTGCCCTAGAAACCACCAACTCTCTCTGCCGGAAGTCTTTGGCCCTTTTGGGACAGACATTTTCCTTGG
CCTCTTCTTTCCGGCAGGAGAAAATCTTAGAAGCTGTCGGCCTGCAAGATATAGCTCCCTCACCTGCTGCGTTTCCAAACTTCGAAGACT
CCACTTTGTTTGGGCGAGAGTACATAGACCACCTGAAGGCCTGGCTAGTCAGCAGCGGATGTCCCCTCCAGGTTAAGAAAGCCGAACCAG
AGCCGATGCGAGAGGAGGAGAAAATGATTCCTCCTACGAAACCTGAAATTCAGGCCAAGGCTCCAAGTAGTCTGAGTGATGCTGTCCCCC
AGCGAGCAGATCACAGGGTAGTGGGCACCATCGACCAGCTTGTGAAACGTGTCATCGAAGGCAGCCTGTCTCCCAAAGAGAGAACTCTTC
TCAAAGAGGACCCTGCTTACTGGTTTTTGTCTGATGAAAATAGTCTGGAGTATAAATATTACAAGCTGAAGTTGGCAGAAATGCAGCGGA
TGAGCGAGAACTTGCGAGGAGCCGACCAGAAGCCGACCTCAGCAGACTGTGCAGTGAGGGCCATGCTGTACTCCCGGGCTGTCCGCAACC
TCAAGAAGAAACTCCTTCCGTGGCAGCGGCGGGGGCTCCTCCGTGCTCAAGGGCTCCGGGGCTGGAAGGCGAGGAGAGCGACCACCGGGA
CCCAGACCCTCCTATCCTCAGGCACCAGGCTGAAACACCACGGCCGGCAGGCTCCAGGCCTCTCACAGGCAAAACCATCCCTGCCAGACA
GAAATGATGCTGCCAAGGACTGCCCGCCAGACCCAGTTGGACCTTCTCCTCAGGACCCCAGCTTAGAAGCCTCAGGCCCATCCCCCAAGC
CAGCAGGAGTGGACATCTCTGAAGCACCTCAGACCTCTTCTCCCTGCCCATCTGCTGACATTGACATGAAGACAATGGAGACTGCAGAGA
AACTGGCTAGATTTGTTGCTCAGGTGGGACCAGAGATCGAACAATTCAGCATAGAAAACAGCACCGATAACCCTGACCTGTGGTTTCTAC
ATGACCAAAATAGTTCTGCTTTCAAATTCTATCGAAAGAAAGTGTTTGAACTATGTCCATCAATTTGTTTCACGTCATCTCCGCACAACC
TTCACACTGGTGGTGGTGACACCACGGGTTCTCAGGAGAGCCCCGTGGACCTCATGGAAGGGGAAGCAGAGTTTGAAGACGAGCCCCCTC
CGCGGGAGGCTGAGCTGGAGAGCCCAGAGGTGATGCCTGAGGAGGAGGACGAGGACGATGAGGATGGGGGAGAGGAGGCCCCCGCTCCTG
GAGGGGCGGGCAAGTCTGAGGGCAGCACCCCTGCCGACGGCCTTCCCGGCGAGGCTGCCGAGGACGACCTGGCTGGAGCACCTGCCTTGT
CACAGGCCTCCTCAGGTACCTGCTTCCCTCGGAAGAGGATCAGCAGCAAGTCATTGAAGGTTGGCATGATTCCAGCTCCCAAGAGAGTGT
GTCTCATCCAGGAGCCAAAAGGCTTTATCCTGTGGATAAACGCAGAGTGAACGAGTTTGGGGAGTCCTACGAGGAGAAGGCCACGCGGGC
GCCCCACACGGACTGAAGGCCGCCCGGGCTGCCGCCAGCCAAGTGCAACTTGAATTGTCAATGAGTATTTTTGGAAGCATTTGGAGGAAT
TCCTAGACATTGCGTTTTCTGTGTTGCCAAAATCCCTTCGGACATTTCTCAGACATCTCCCAAGTTCCCATCACGTCAGATTTGGAGCTG
GTAGCGCTTACGATGCCCCCACGTGTGAACATCTGTCTTGGTCACAGAGCTGGGTGCTGCCGGTCACCTTGAGCTGTGGTGGCTCCCGGC
ACACGAGTGTCCGGGGTTCGGCCATGTCCTCACGCGGGCAGGGGTGGGAGCCCTCACAGGCAAGGGGGCTGTTGGATTTCCATTTCAGGT
GGTTTTCTAAGTGCTCCTTATGTGAATTTCAAACACGTATGGAATTCATTCCGCATGGACTCTGGGATCAAAGGCTCTTTCCTCTTTTGT

>88002_88002_4_SUGP2-CLPTM1L_SUGP2_chr19_19114977_ENST00000600377_CLPTM1L_chr5_1318568_ENST00000320927_length(amino acids)=999AA_BP=
MSPPRAAAAAGQNNMAARRITQETFDAVLQEKAKRYHMDASGEAVSETLQFKAQDLLRAVPRSRAEMYDDVHSDGRYSLSGSVAHSRDAG
REGLRSDVFPGPSFRSSNPSISDDSYFRKECGRDLEFSHSDSRDQVIGHRKLGHFRSQDWKFALRGSWEQDFGHPVSQESSWSQEYSFGP
SAVLGDFGSSRLIEKECLEKESRDYDVDHPGEADSVLRGGSQVQARGRALNIVDQEGSLLGKGETQGLLTAKGGVGKLVTLRNVSTKKIP
TVNRITPKTQGTNQIQKNTPSPDVTLGTNPGTEDIQFPIQKIPLGLDLKNLRLPRRKMSFDIIDKSDVFSRFGIEIIKWAGFHTIKDDIK
FSQLFQTLFELETETCAKMLASFKCSLKPEHRDFCFFTIKFLKHSALKTPRVDNEFLNMLLDKGAVKTKNCFFEIIKPFDKYIMRLQDRL
LKSVTPLLMACNAYELSVKMKTLSNPLDLALALETTNSLCRKSLALLGQTFSLASSFRQEKILEAVGLQDIAPSPAAFPNFEDSTLFGRE
YIDHLKAWLVSSGCPLQVKKAEPEPMREEEKMIPPTKPEIQAKAPSSLSDAVPQRADHRVVGTIDQLVKRVIEGSLSPKERTLLKEDPAY
WFLSDENSLEYKYYKLKLAEMQRMSENLRGADQKPTSADCAVRAMLYSRAVRNLKKKLLPWQRRGLLRAQGLRGWKARRATTGTQTLLSS
GTRLKHHGRQAPGLSQAKPSLPDRNDAAKDCPPDPVGPSPQDPSLEASGPSPKPAGVDISEAPQTSSPCPSADIDMKTMETAEKLARFVA
QVGPEIEQFSIENSTDNPDLWFLHDQNSSAFKFYRKKVFELCPSICFTSSPHNLHTGGGDTTGSQESPVDLMEGEAEFEDEPPPREAELE
SPEVMPEEEDEDDEDGGEEAPAPGGAGKSEGSTPADGLPGEAAEDDLAGAPALSQASSGTCFPRKRISSKSLKVGMIPAPKRVCLIQEPK

--------------------------------------------------------------
>88002_88002_5_SUGP2-CLPTM1L_SUGP2_chr19_19114977_ENST00000601879_CLPTM1L_chr5_1318568_ENST00000320895_length(transcript)=3937nt_BP=3227nt
AACCACGTACCCGAGGGTCGCGCCAGCCCGACCCTGCGGCACCCCCACTCCCCACTCCGCGCGGGACAGGCCTCGGCAGCCGCAGCGTCT
CACCCGGTCTTCGCGGCCACGTGGGGAAAGGTGGGGCGCGCGGTTGTCACCCAGGGAGCCGCCTCTAGCCCCTTCCGGCCGCCGTACGCG
CGCAGGCGCTGTGGCGCCCCTAGGCTTGGCCTCCCAGAGACTCGCGGACGCTCACGATAACCAAGGACGACCGCGAACCAAGTGTATTTT
TTTCTCTCTCACCATAGGGCAAAATAACATGGCAGCCAGACGAATTACACAGGAGACTTTTGATGCTGTATTACAAGAAAAAGCCAAACG
ATATCACATGGATGCCAGTGGTGAGGCTGTAAGCGAAACTCTTCAGTTTAAAGCTCAAGATCTCTTAAGGGCAGTCCCAAGATCCAGAGC
AGAGATGTATGATGACGTCCACAGCGATGGCAGATACTCCCTCAGTGGATCTGTAGCTCACTCTAGAGATGCCGGAAGAGAAGGCCTGAG
AAGTGACGTATTTCCAGGGCCTTCCTTCAGATCAAGCAACCCTTCCATCAGTGATGACAGCTACTTTCGCAAAGAATGTGGCCGGGATCT
GGAATTTTCTCACTCTGATTCTCGGGACCAGGTCATTGGCCACCGGAAATTGGGGCATTTCCGTTCTCAGGACTGGAAATTTGCGCTCCG
TGGTTCTTGGGAACAAGACTTTGGCCATCCAGTTTCTCAAGAGTCCTCTTGGTCACAGGAGTATAGTTTTGGTCCCTCTGCAGTTTTGGG
GGACTTTGGATCTTCCAGGCTGATTGAGAAAGAGTGTTTGGAGAAGGAGAGTCGGGATTATGACGTGGACCATCCTGGGGAGGCTGACTC
TGTGCTTAGGGGCGGCAGTCAAGTCCAGGCCAGAGGTCGAGCTCTAAACATCGTTGACCAGGAAGGTTCCCTCCTAGGAAAGGGGGAGAC
TCAGGGCCTGCTCACAGCTAAGGGGGGTGTTGGGAAACTTGTCACATTGAGAAATGTGAGCACAAAAAAAATACCCACCGTGAATCGTAT
TACTCCCAAAACTCAGGGCACTAACCAAATCCAGAAAAACACTCCAAGTCCTGATGTGACCCTGGGGACAAACCCAGGGACAGAAGATAT
CCAGTTCCCCATTCAGAAGATCCCTCTGGGGCTGGATCTGAAGAATCTTCGGCTCCCCAGAAGAAAGATGAGCTTTGACATCATAGATAA
GTCTGATGTTTTTTCAAGATTTGGGATAGAAATAATCAAATGGGCAGGATTCCACACCATAAAAGATGATATTAAATTTTCCCAACTTTT
CCAGACTCTCTTTGAACTTGAAACAGAAACCTGTGCTAAAATGCTTGCCTCATTCAAATGTTCCTTAAAACCAGAGCACAGAGATTTTTG
CTTTTTTACTATCAAATTTTTAAAGCACTCTGCTTTGAAAACACCCAGAGTTGATAATGAGTTTTTAAACATGCTTTTAGACAAAGGTGC
TGTGAAGACCAAAAATTGCTTTTTTGAAATCATAAAGCCTTTTGACAAGTACATAATGAGACTTCAAGACCGGCTTCTGAAGAGTGTCAC
ACCTTTGCTTATGGCCTGCAATGCCTACGAGCTAAGTGTCAAGATGAAGACCCTCAGTAACCCCCTGGACTTGGCTCTTGCCCTAGAAAC
CACCAACTCTCTCTGCCGGAAGTCTTTGGCCCTTTTGGGACAGACATTTTCCTTGGCCTCTTCTTTCCGGCAGGAGAAAATCTTAGAAGC
TGTCGGCCTGCAAGATATAGCTCCCTCACCTGCTGCGTTTCCAAACTTCGAAGACTCCACTTTGTTTGGGCGAGAGTACATAGACCACCT
GAAGGCCTGGCTAGTCAGCAGCGGATGTCCCCTCCAGGTTAAGAAAGCCGAACCAGAGCCGATGCGAGAGGAGGAGAAAATGATTCCTCC
TACGAAACCTGAAATTCAGGCCAAGGCTCCAAGTAGTCTGAGTGATGCTGTCCCCCAGCGAGCAGATCACAGGGTAGTGGGCACCATCGA
CCAGCTTGTGAAACGTGTCATCGAAGGCAGCCTGTCTCCCAAAGAGAGAACTCTTCTCAAAGAGGACCCTGCTTACTGGTTTTTGTCTGA
TGAAAATAGTCTGGAGTATAAATATTACAAGCTGAAGTTGGCAGAAATGCAGCGGATGAGCGAGAACTTGCGAGGAGCCGACCAGAAGCC
GACCTCAGCAGACTGTGCAGTGAGGGCCATGCTGTACTCCCGGGCTGTCCGCAACCTCAAGAAGAAACTCCTTCCGTGGCAGCGGCGGGG
GCTCCTCCGTGCTCAAGGGCTCCGGGGCTGGAAGGCGAGGAGAGCGACCACCGGGACCCAGACCCTCCTATCCTCAGGCACCAGGCTGAA
ACACCACGGCCGGCAGGCTCCAGGCCTCTCACAGGCAAAACCATCCCTGCCAGACAGAAATGATGCTGCCAAGGACTGCCCGCCAGACCC
AGTTGGACCTTCTCCTCAGGACCCCAGCTTAGAAGCCTCAGGCCCATCCCCCAAGCCAGCAGGAGTGGACATCTCTGAAGCACCTCAGAC
CTCTTCTCCCTGCCCATCTGCTGACATTGACATGAAGACAATGGAGACTGCAGAGAAACTGGCTAGATTTGTTGCTCAGGTGGGACCAGA
GATCGAACAATTCAGCATAGAAAACAGCACCGATAACCCTGACCTGTGGTTTCTACATGACCAAAATAGTTCTGCTTTCAAATTCTATCG
AAAGAAAGTGTTTGAACTATGTCCATCAATTTGTTTCACGTCATCTCCGCACAACCTTCACACTGGTGGTGGTGACACCACGGGTTCTCA
GGAGAGCCCCGTGGACCTCATGGAAGGGGAAGCAGAGTTTGAAGACGAGCCCCCTCCGCGGGAGGCTGAGCTGGAGAGCCCAGAGGTGAT
GCCTGAGGAGGAGGACGAGGACGATGAGGATGGGGGAGAGGAGGCCCCCGCTCCTGGAGGGGCGGGCAAGTCTGAGGGCAGCACCCCTGC
CGACGGCCTTCCCGGCGAGGCTGCCGAGGACGACCTGGCTGGAGCACCTGCCTTGTCACAGGCCTCCTCAGGTACCTGCTTCCCTCGGAA
GAGGATCAGCAGCAAGTCATTGAAGGTTGGCATGATTCCAGCTCCCAAGAGAGTGTGTCTCATCCAGGAGCCAAAAGGCTTTATCCTGTG
GATAAACGCAGAGTGAACGAGTTTGGGGAGTCCTACGAGGAGAAGGCCACGCGGGCGCCCCACACGGACTGAAGGCCGCCCGGGCTGCCG
CCAGCCAAGTGCAACTTGAATTGTCAATGAGTATTTTTGGAAGCATTTGGAGGAATTCCTAGACATTGCGTTTTCTGTGTTGCCAAAATC
CCTTCGGACATTTCTCAGACATCTCCCAAGTTCCCATCACGTCAGATTTGGAGCTGGTAGCGCTTACGATGCCCCCACGTGTGAACATCT
GTCTTGGTCACAGAGCTGGGTGCTGCCGGTCACCTTGAGCTGTGGTGGCTCCCGGCACACGAGTGTCCGGGGTTCGGCCATGTCCTCACG
CGGGCAGGGGTGGGAGCCCTCACAGGCAAGGGGGCTGTTGGATTTCCATTTCAGGTGGTTTTCTAAGTGCTCCTTATGTGAATTTCAAAC
ACGTATGGAATTCATTCCGCATGGACTCTGGGATCAAAGGCTCTTTCCTCTTTTGTTTGAGAGTTGGTTGTTTTAAAGCTTAATGTATGT
TTCTATTTTAAAATAAATTTTTCTGGCTGTGGCATTTTTCTTGACCTGGTATAATGAAAGTATTTCGGATATTTGAGTTTAACCCTTTTC

>88002_88002_5_SUGP2-CLPTM1L_SUGP2_chr19_19114977_ENST00000601879_CLPTM1L_chr5_1318568_ENST00000320895_length(amino acids)=1040AA_BP=
MSPREPPLAPSGRRTRAGAVAPLGLASQRLADAHDNQGRPRTKCIFFSLTIGQNNMAARRITQETFDAVLQEKAKRYHMDASGEAVSETL
QFKAQDLLRAVPRSRAEMYDDVHSDGRYSLSGSVAHSRDAGREGLRSDVFPGPSFRSSNPSISDDSYFRKECGRDLEFSHSDSRDQVIGH
RKLGHFRSQDWKFALRGSWEQDFGHPVSQESSWSQEYSFGPSAVLGDFGSSRLIEKECLEKESRDYDVDHPGEADSVLRGGSQVQARGRA
LNIVDQEGSLLGKGETQGLLTAKGGVGKLVTLRNVSTKKIPTVNRITPKTQGTNQIQKNTPSPDVTLGTNPGTEDIQFPIQKIPLGLDLK
NLRLPRRKMSFDIIDKSDVFSRFGIEIIKWAGFHTIKDDIKFSQLFQTLFELETETCAKMLASFKCSLKPEHRDFCFFTIKFLKHSALKT
PRVDNEFLNMLLDKGAVKTKNCFFEIIKPFDKYIMRLQDRLLKSVTPLLMACNAYELSVKMKTLSNPLDLALALETTNSLCRKSLALLGQ
TFSLASSFRQEKILEAVGLQDIAPSPAAFPNFEDSTLFGREYIDHLKAWLVSSGCPLQVKKAEPEPMREEEKMIPPTKPEIQAKAPSSLS
DAVPQRADHRVVGTIDQLVKRVIEGSLSPKERTLLKEDPAYWFLSDENSLEYKYYKLKLAEMQRMSENLRGADQKPTSADCAVRAMLYSR
AVRNLKKKLLPWQRRGLLRAQGLRGWKARRATTGTQTLLSSGTRLKHHGRQAPGLSQAKPSLPDRNDAAKDCPPDPVGPSPQDPSLEASG
PSPKPAGVDISEAPQTSSPCPSADIDMKTMETAEKLARFVAQVGPEIEQFSIENSTDNPDLWFLHDQNSSAFKFYRKKVFELCPSICFTS
SPHNLHTGGGDTTGSQESPVDLMEGEAEFEDEPPPREAELESPEVMPEEEDEDDEDGGEEAPAPGGAGKSEGSTPADGLPGEAAEDDLAG

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Fusion Gene PPI Analysis for SUGP2-CLPTM1L


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for SUGP2-CLPTM1L


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for SUGP2-CLPTM1L


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource