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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:SUGT1-CNOT10 (FusionGDB2 ID:88012)

Fusion Gene Summary for SUGT1-CNOT10

check button Fusion gene summary
Fusion gene informationFusion gene name: SUGT1-CNOT10
Fusion gene ID: 88012
HgeneTgene
Gene symbol

SUGT1

CNOT10

Gene ID

10910

25904

Gene nameSGT1 homolog, MIS12 kinetochore complex assembly cochaperoneCCR4-NOT transcription complex subunit 10
SynonymsSGT1-
Cytomap

13q14.3

3p22.3

Type of geneprotein-codingprotein-coding
Descriptionprotein SGT1 homologSGT1, suppressor of G2 allele of SKP1putative 40-6-3 proteinsuppressor of G2 allele of SKP1, S. cerevisiae, homolog ofCCR4-NOT transcription complex subunit 10
Modification date2020031320200313
UniProtAcc.

Q9H9A5

Ensembl transtripts involved in fusion geneENST00000483074, ENST00000310528, 
ENST00000343788, ENST00000535397, 
ENST00000328834, ENST00000331889, 
ENST00000454516, ENST00000538368, 
ENST00000463697, 
Fusion gene scores* DoF score6 X 7 X 5=2108 X 7 X 6=336
# samples 78
** MAII scorelog2(7/210*10)=-1.58496250072116
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(8/336*10)=-2.0703893278914
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: SUGT1 [Title/Abstract] AND CNOT10 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointSUGT1(53238192)-CNOT10(32800949), # samples:1
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneSUGT1

GO:0031647

regulation of protein stability

23935490

HgeneSUGT1

GO:0043947

positive regulation by host of symbiont catalytic activity

23935490


check buttonFusion gene breakpoints across SUGT1 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across CNOT10 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4OVTCGA-57-1994SUGT1chr13

53238192

+CNOT10chr3

32800949

+


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Fusion Gene ORF analysis for SUGT1-CNOT10

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
3UTR-3CDSENST00000483074ENST00000328834SUGT1chr13

53238192

+CNOT10chr3

32800949

+
3UTR-3CDSENST00000483074ENST00000331889SUGT1chr13

53238192

+CNOT10chr3

32800949

+
3UTR-3CDSENST00000483074ENST00000454516SUGT1chr13

53238192

+CNOT10chr3

32800949

+
3UTR-3CDSENST00000483074ENST00000538368SUGT1chr13

53238192

+CNOT10chr3

32800949

+
3UTR-intronENST00000483074ENST00000463697SUGT1chr13

53238192

+CNOT10chr3

32800949

+
5CDS-intronENST00000310528ENST00000463697SUGT1chr13

53238192

+CNOT10chr3

32800949

+
5CDS-intronENST00000343788ENST00000463697SUGT1chr13

53238192

+CNOT10chr3

32800949

+
5CDS-intronENST00000535397ENST00000463697SUGT1chr13

53238192

+CNOT10chr3

32800949

+
In-frameENST00000310528ENST00000328834SUGT1chr13

53238192

+CNOT10chr3

32800949

+
In-frameENST00000310528ENST00000331889SUGT1chr13

53238192

+CNOT10chr3

32800949

+
In-frameENST00000310528ENST00000454516SUGT1chr13

53238192

+CNOT10chr3

32800949

+
In-frameENST00000310528ENST00000538368SUGT1chr13

53238192

+CNOT10chr3

32800949

+
In-frameENST00000343788ENST00000328834SUGT1chr13

53238192

+CNOT10chr3

32800949

+
In-frameENST00000343788ENST00000331889SUGT1chr13

53238192

+CNOT10chr3

32800949

+
In-frameENST00000343788ENST00000454516SUGT1chr13

53238192

+CNOT10chr3

32800949

+
In-frameENST00000343788ENST00000538368SUGT1chr13

53238192

+CNOT10chr3

32800949

+
In-frameENST00000535397ENST00000328834SUGT1chr13

53238192

+CNOT10chr3

32800949

+
In-frameENST00000535397ENST00000331889SUGT1chr13

53238192

+CNOT10chr3

32800949

+
In-frameENST00000535397ENST00000454516SUGT1chr13

53238192

+CNOT10chr3

32800949

+
In-frameENST00000535397ENST00000538368SUGT1chr13

53238192

+CNOT10chr3

32800949

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000343788SUGT1chr1353238192+ENST00000331889CNOT10chr332800949+1343600821239385
ENST00000343788SUGT1chr1353238192+ENST00000328834CNOT10chr332800949+1504600821239385
ENST00000343788SUGT1chr1353238192+ENST00000538368CNOT10chr332800949+129360082849255
ENST00000343788SUGT1chr1353238192+ENST00000454516CNOT10chr332800949+1341600821239385
ENST00000535397SUGT1chr1353238192+ENST00000331889CNOT10chr332800949+13706273731266297
ENST00000535397SUGT1chr1353238192+ENST00000328834CNOT10chr332800949+15316273731266297
ENST00000535397SUGT1chr1353238192+ENST00000538368CNOT10chr332800949+1320627373876167
ENST00000535397SUGT1chr1353238192+ENST00000454516CNOT10chr332800949+13686273731266297
ENST00000310528SUGT1chr1353238192+ENST00000331889CNOT10chr332800949+1220477551116353
ENST00000310528SUGT1chr1353238192+ENST00000328834CNOT10chr332800949+1381477551116353
ENST00000310528SUGT1chr1353238192+ENST00000538368CNOT10chr332800949+117047755726223
ENST00000310528SUGT1chr1353238192+ENST00000454516CNOT10chr332800949+1218477551116353

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000343788ENST00000331889SUGT1chr1353238192+CNOT10chr332800949+0.0024803370.9975197
ENST00000343788ENST00000328834SUGT1chr1353238192+CNOT10chr332800949+0.0016039930.998396
ENST00000343788ENST00000538368SUGT1chr1353238192+CNOT10chr332800949+0.0021330230.997867
ENST00000343788ENST00000454516SUGT1chr1353238192+CNOT10chr332800949+0.0025446360.9974554
ENST00000535397ENST00000331889SUGT1chr1353238192+CNOT10chr332800949+0.0033011230.9966988
ENST00000535397ENST00000328834SUGT1chr1353238192+CNOT10chr332800949+0.002420460.9975795
ENST00000535397ENST00000538368SUGT1chr1353238192+CNOT10chr332800949+0.0037197320.99628025
ENST00000535397ENST00000454516SUGT1chr1353238192+CNOT10chr332800949+0.003389110.9966108
ENST00000310528ENST00000331889SUGT1chr1353238192+CNOT10chr332800949+0.0017504240.9982496
ENST00000310528ENST00000328834SUGT1chr1353238192+CNOT10chr332800949+0.0011389350.9988611
ENST00000310528ENST00000538368SUGT1chr1353238192+CNOT10chr332800949+0.0017573510.9982426
ENST00000310528ENST00000454516SUGT1chr1353238192+CNOT10chr332800949+0.0017875110.99821246

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Fusion Genomic Features for SUGT1-CNOT10


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
SUGT1chr1353238192+CNOT10chr332800949+1.29E-081
SUGT1chr1353238192+CNOT10chr332800949+1.29E-081

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for SUGT1-CNOT10


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr13:53238192/chr3:32800949)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
.CNOT10

Q9H9A5

FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation. Additional complex functions may be a consequence of its influence on mRNA expression. Is not required for association of CNOT7 to the CCR4-NOT complex. {ECO:0000269|PubMed:23221646}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneSUGT1chr13:53238192chr3:32800949ENST00000310528+81311_44140334.0RepeatNote=TPR 1
HgeneSUGT1chr13:53238192chr3:32800949ENST00000310528+81345_78140334.0RepeatNote=TPR 2
HgeneSUGT1chr13:53238192chr3:32800949ENST00000310528+81379_112140334.0RepeatNote=TPR 3
HgeneSUGT1chr13:53238192chr3:32800949ENST00000343788+91411_44172366.0RepeatNote=TPR 1
HgeneSUGT1chr13:53238192chr3:32800949ENST00000343788+91445_78172366.0RepeatNote=TPR 2
HgeneSUGT1chr13:53238192chr3:32800949ENST00000343788+91479_112172366.0RepeatNote=TPR 3

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneSUGT1chr13:53238192chr3:32800949ENST00000310528+813169_258140334.0DomainCS
HgeneSUGT1chr13:53238192chr3:32800949ENST00000310528+813276_365140334.0DomainSGS
HgeneSUGT1chr13:53238192chr3:32800949ENST00000343788+914169_258172366.0DomainCS
HgeneSUGT1chr13:53238192chr3:32800949ENST00000343788+914276_365172366.0DomainSGS
TgeneCNOT10chr13:53238192chr3:32800949ENST00000328834121974_107531745.0Coiled coilOntology_term=ECO:0000255
TgeneCNOT10chr13:53238192chr3:32800949ENST00000331889111874_107504718.0Coiled coilOntology_term=ECO:0000255
TgeneCNOT10chr13:53238192chr3:32800949ENST00000454516121974_107591805.0Coiled coilOntology_term=ECO:0000255


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Fusion Gene Sequence for SUGT1-CNOT10


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>88012_88012_1_SUGT1-CNOT10_SUGT1_chr13_53238192_ENST00000310528_CNOT10_chr3_32800949_ENST00000328834_length(transcript)=1381nt_BP=477nt
GAGGTGGTAACCGTGATAGTAGCAGCTCCGGCGGCAGCAACAGCGACTACGAGGGATGGCGGCGGCTGCAGCAGGAACTGCAACATCCCA
GAGGTTTTTCCAGAGCTTCTCGGATGCCCTAATCGACGAGGACCCCCAGGCGGCGTTAGAGGAGCTGACTAAGGCTTTGGAACAGAAACC
AGATGATGCACAGTATTATTGTCAAAGAGCTTATTGTCACATTCTTCTTGGGAATTACTGTGTTGCTGTTGCTGATGCAAAGAAGTCTCT
AGAACTCAATCCAAATAATTCCACTGCTATGCTGAGAAAAGGAATATGTGAATACCATGAAAAAAACTATGCTGCTGCCCTAGAAACTTT
TACAGAAGGACAAAAATTAGATAGTGCAGATGCTAATTTCAGTGTCTGGATTAAAAGGTGTCAAGAAGCTCAGAATGGCTCAGAATCTGA
GGTGTGGACTCATCAGTCAAAAATCAAGTGCTCCATACTTGCTTGCAGTGCCTACGTGGCTCTGGCTTTGGGTGATAACCTCATGGCTTT
GAATCATGCAGATAAACTTCTTCAGCAGCCCAAGCTGTCAGGATCTCTTAAGTTTTTGGGACATTTATATGCTGCAGAAGCCCTCATCTC
TCTCGACAGAATATCTGATGCCATTACTCACTTGAACCCGGAGAATGTCACTGATGTCTCCTTAGGGATCTCTTCAAATGAGCAGGACCA
AGGATCAGACAAAGGTGAAAATGAAGCAATGGAATCCTCTGGTAAGCGGGCCCCTCAGTGCTACCCCAGTTCCGTCAACTCTGCCAGGAC
TGTGATGCTGTTCAACCTTGGCAGCGCTTACTGCCTGAGGAGCGAATATGACAAAGCCCGAAAGTGTCTCCACCAGGCGGCTTCAATGAT
CCATCCTAAAGAGGTGCCCCCTGAGGCCATCTTGCTGGCAGTCTACCTTGAACTGCAGAATGGTAATACTCAGCTGGCCTTACAGATCAT
CAAAAGGAATCAGCTGCTCCCTGCAGTGAAAACACACTCTGAAGTGAGAAAGAAGCCAGTGTTTCAGCCTGTCCACCCGATCCAGCCCAT
CCAAATGCCGGCTTTCACCACTGTGCAGAGAAAGTGATACTTCACTTTTGGAAAACTGTTACCTGAGACCCAGGGGAGAATTTACTGGCC
ATTTTAGTTGTATCACAGCAGAATGAATAAAAGATGGTGAAGGCTGTTAATTTTGAGTCAATTCTACCCCTGACATTTGGCCAAAAGCTT
ACTTAAAATTAAGGATTTACTAAGTCATCATCAGCTGTTTTTCTTAATTTCAGCCAGACTATTAATTTTGAGCCATTATGTAATATATGC

>88012_88012_1_SUGT1-CNOT10_SUGT1_chr13_53238192_ENST00000310528_CNOT10_chr3_32800949_ENST00000328834_length(amino acids)=353AA_BP=0
MAAAAAGTATSQRFFQSFSDALIDEDPQAALEELTKALEQKPDDAQYYCQRAYCHILLGNYCVAVADAKKSLELNPNNSTAMLRKGICEY
HEKNYAAALETFTEGQKLDSADANFSVWIKRCQEAQNGSESEVWTHQSKIKCSILACSAYVALALGDNLMALNHADKLLQQPKLSGSLKF
LGHLYAAEALISLDRISDAITHLNPENVTDVSLGISSNEQDQGSDKGENEAMESSGKRAPQCYPSSVNSARTVMLFNLGSAYCLRSEYDK

--------------------------------------------------------------
>88012_88012_2_SUGT1-CNOT10_SUGT1_chr13_53238192_ENST00000310528_CNOT10_chr3_32800949_ENST00000331889_length(transcript)=1220nt_BP=477nt
GAGGTGGTAACCGTGATAGTAGCAGCTCCGGCGGCAGCAACAGCGACTACGAGGGATGGCGGCGGCTGCAGCAGGAACTGCAACATCCCA
GAGGTTTTTCCAGAGCTTCTCGGATGCCCTAATCGACGAGGACCCCCAGGCGGCGTTAGAGGAGCTGACTAAGGCTTTGGAACAGAAACC
AGATGATGCACAGTATTATTGTCAAAGAGCTTATTGTCACATTCTTCTTGGGAATTACTGTGTTGCTGTTGCTGATGCAAAGAAGTCTCT
AGAACTCAATCCAAATAATTCCACTGCTATGCTGAGAAAAGGAATATGTGAATACCATGAAAAAAACTATGCTGCTGCCCTAGAAACTTT
TACAGAAGGACAAAAATTAGATAGTGCAGATGCTAATTTCAGTGTCTGGATTAAAAGGTGTCAAGAAGCTCAGAATGGCTCAGAATCTGA
GGTGTGGACTCATCAGTCAAAAATCAAGTGCTCCATACTTGCTTGCAGTGCCTACGTGGCTCTGGCTTTGGGTGATAACCTCATGGCTTT
GAATCATGCAGATAAACTTCTTCAGCAGCCCAAGCTGTCAGGATCTCTTAAGTTTTTGGGACATTTATATGCTGCAGAAGCCCTCATCTC
TCTCGACAGAATATCTGATGCCATTACTCACTTGAACCCGGAGAATGTCACTGATGTCTCCTTAGGGATCTCTTCAAATGAGCAGGACCA
AGGATCAGACAAAGGTGAAAATGAAGCAATGGAATCCTCTGGTAAGCGGGCCCCTCAGTGCTACCCCAGTTCCGTCAACTCTGCCAGGAC
TGTGATGCTGTTCAACCTTGGCAGCGCTTACTGCCTGAGGAGCGAATATGACAAAGCCCGAAAGTGTCTCCACCAGGCGGCTTCAATGAT
CCATCCTAAAGAGGTGCCCCCTGAGGCCATCTTGCTGGCAGTCTACCTTGAACTGCAGAATGGTAATACTCAGCTGGCCTTACAGATCAT
CAAAAGGAATCAGCTGCTCCCTGCAGTGAAAACACACTCTGAAGTGAGAAAGAAGCCAGTGTTTCAGCCTGTCCACCCGATCCAGCCCAT
CCAAATGCCGGCTTTCACCACTGTGCAGAGAAAGTGATACTTCACTTTTGGAAAACTGTTACCTGAGACCCAGGGGAGAATTTACTGGCC

>88012_88012_2_SUGT1-CNOT10_SUGT1_chr13_53238192_ENST00000310528_CNOT10_chr3_32800949_ENST00000331889_length(amino acids)=353AA_BP=0
MAAAAAGTATSQRFFQSFSDALIDEDPQAALEELTKALEQKPDDAQYYCQRAYCHILLGNYCVAVADAKKSLELNPNNSTAMLRKGICEY
HEKNYAAALETFTEGQKLDSADANFSVWIKRCQEAQNGSESEVWTHQSKIKCSILACSAYVALALGDNLMALNHADKLLQQPKLSGSLKF
LGHLYAAEALISLDRISDAITHLNPENVTDVSLGISSNEQDQGSDKGENEAMESSGKRAPQCYPSSVNSARTVMLFNLGSAYCLRSEYDK

--------------------------------------------------------------
>88012_88012_3_SUGT1-CNOT10_SUGT1_chr13_53238192_ENST00000310528_CNOT10_chr3_32800949_ENST00000454516_length(transcript)=1218nt_BP=477nt
GAGGTGGTAACCGTGATAGTAGCAGCTCCGGCGGCAGCAACAGCGACTACGAGGGATGGCGGCGGCTGCAGCAGGAACTGCAACATCCCA
GAGGTTTTTCCAGAGCTTCTCGGATGCCCTAATCGACGAGGACCCCCAGGCGGCGTTAGAGGAGCTGACTAAGGCTTTGGAACAGAAACC
AGATGATGCACAGTATTATTGTCAAAGAGCTTATTGTCACATTCTTCTTGGGAATTACTGTGTTGCTGTTGCTGATGCAAAGAAGTCTCT
AGAACTCAATCCAAATAATTCCACTGCTATGCTGAGAAAAGGAATATGTGAATACCATGAAAAAAACTATGCTGCTGCCCTAGAAACTTT
TACAGAAGGACAAAAATTAGATAGTGCAGATGCTAATTTCAGTGTCTGGATTAAAAGGTGTCAAGAAGCTCAGAATGGCTCAGAATCTGA
GGTGTGGACTCATCAGTCAAAAATCAAGTGCTCCATACTTGCTTGCAGTGCCTACGTGGCTCTGGCTTTGGGTGATAACCTCATGGCTTT
GAATCATGCAGATAAACTTCTTCAGCAGCCCAAGCTGTCAGGATCTCTTAAGTTTTTGGGACATTTATATGCTGCAGAAGCCCTCATCTC
TCTCGACAGAATATCTGATGCCATTACTCACTTGAACCCGGAGAATGTCACTGATGTCTCCTTAGGGATCTCTTCAAATGAGCAGGACCA
AGGATCAGACAAAGGTGAAAATGAAGCAATGGAATCCTCTGGTAAGCGGGCCCCTCAGTGCTACCCCAGTTCCGTCAACTCTGCCAGGAC
TGTGATGCTGTTCAACCTTGGCAGCGCTTACTGCCTGAGGAGCGAATATGACAAAGCCCGAAAGTGTCTCCACCAGGCGGCTTCAATGAT
CCATCCTAAAGAGGTGCCCCCTGAGGCCATCTTGCTGGCAGTCTACCTTGAACTGCAGAATGGTAATACTCAGCTGGCCTTACAGATCAT
CAAAAGGAATCAGCTGCTCCCTGCAGTGAAAACACACTCTGAAGTGAGAAAGAAGCCAGTGTTTCAGCCTGTCCACCCGATCCAGCCCAT
CCAAATGCCGGCTTTCACCACTGTGCAGAGAAAGTGATACTTCACTTTTGGAAAACTGTTACCTGAGACCCAGGGGAGAATTTACTGGCC

>88012_88012_3_SUGT1-CNOT10_SUGT1_chr13_53238192_ENST00000310528_CNOT10_chr3_32800949_ENST00000454516_length(amino acids)=353AA_BP=0
MAAAAAGTATSQRFFQSFSDALIDEDPQAALEELTKALEQKPDDAQYYCQRAYCHILLGNYCVAVADAKKSLELNPNNSTAMLRKGICEY
HEKNYAAALETFTEGQKLDSADANFSVWIKRCQEAQNGSESEVWTHQSKIKCSILACSAYVALALGDNLMALNHADKLLQQPKLSGSLKF
LGHLYAAEALISLDRISDAITHLNPENVTDVSLGISSNEQDQGSDKGENEAMESSGKRAPQCYPSSVNSARTVMLFNLGSAYCLRSEYDK

--------------------------------------------------------------
>88012_88012_4_SUGT1-CNOT10_SUGT1_chr13_53238192_ENST00000310528_CNOT10_chr3_32800949_ENST00000538368_length(transcript)=1170nt_BP=477nt
GAGGTGGTAACCGTGATAGTAGCAGCTCCGGCGGCAGCAACAGCGACTACGAGGGATGGCGGCGGCTGCAGCAGGAACTGCAACATCCCA
GAGGTTTTTCCAGAGCTTCTCGGATGCCCTAATCGACGAGGACCCCCAGGCGGCGTTAGAGGAGCTGACTAAGGCTTTGGAACAGAAACC
AGATGATGCACAGTATTATTGTCAAAGAGCTTATTGTCACATTCTTCTTGGGAATTACTGTGTTGCTGTTGCTGATGCAAAGAAGTCTCT
AGAACTCAATCCAAATAATTCCACTGCTATGCTGAGAAAAGGAATATGTGAATACCATGAAAAAAACTATGCTGCTGCCCTAGAAACTTT
TACAGAAGGACAAAAATTAGATAGTGCAGATGCTAATTTCAGTGTCTGGATTAAAAGGTGTCAAGAAGCTCAGAATGGCTCAGAATCTGA
GGTGTGGACTCATCAGTCAAAAATCAAGTGCTCCATACTTGCTTGCAGTGCCTACGTGGCTCTGGCTTTGGGTGATAACCTCATGGCTTT
GAATCATGCAGATAAACTTCTTCAGCAGCCCAAGCTGTCAGGATCTCTTAAGTTTTTGGGACATTTATATGCTGCAGAAGCCCTCATCTC
TCTCGACAGAATATCTGATGCCATTACTCACTTGAACCCGGAGAATGTCACTGATGTCTCCTTAGGGATCTCTTCAAATGAGCAGGACCA
AGGTTAATGAGGACATCTTTGATCAGAACTGGTCACTGTTTCCATTTCCCTCCTGTCATAATTCAGGATGTGTGGAAATTTAGGCATGGT
GGTAATGAGAAGAAAGTTTTAGGTTGGCTTTCCACATTTTTGTCTGTACTTACTTTGTAGCAGTTGTTTGCTAAGTAGACCTGAGAGTTA
ATGATCACATCATCTAAATTCTCACTTTTGAAAGGCTGGTACTGTTAGAATGGTTAATTTTGGTTCTGATACTATTTATTTGTTTTCCTT
TGGAGTGATTCTAAAATCCATAGGGGAGTAAAAATATTGCATTCAAGAGTCAGTTTTAGTCCAGGCGTGGTGGCTCACGCCTGTAATCCC
AGCACTTTGGGAGGCTGTAGCAGGAGGGTCACTTGAGCCCAAGAGTTCAAGACCAGCCTGGGCAACCTGGTGAGACCCTGTCTCTATTTT

>88012_88012_4_SUGT1-CNOT10_SUGT1_chr13_53238192_ENST00000310528_CNOT10_chr3_32800949_ENST00000538368_length(amino acids)=223AA_BP=0
MAAAAAGTATSQRFFQSFSDALIDEDPQAALEELTKALEQKPDDAQYYCQRAYCHILLGNYCVAVADAKKSLELNPNNSTAMLRKGICEY
HEKNYAAALETFTEGQKLDSADANFSVWIKRCQEAQNGSESEVWTHQSKIKCSILACSAYVALALGDNLMALNHADKLLQQPKLSGSLKF

--------------------------------------------------------------
>88012_88012_5_SUGT1-CNOT10_SUGT1_chr13_53238192_ENST00000343788_CNOT10_chr3_32800949_ENST00000328834_length(transcript)=1504nt_BP=600nt
CAGAAGTTTCCCCCTTGGGCGGTGGTGGAGGTGGTAACCGTGATAGTAGCAGCTCCGGCGGCAGCAACAGCGACTACGAGGGATGGCGGC
GGCTGCAGCAGGAACTGCAACATCCCAGAGGTTTTTCCAGAGCTTCTCGGATGCCCTAATCGACGAGGACCCCCAGGCGGCGTTAGAGGA
GCTGACTAAGGCTTTGGAACAGAAACCAGATGATGCACAGTATTATTGTCAAAGAGCTTATTGTCACATTCTTCTTGGGAATTACTGTGT
TGCTGTTGCTGATGCAAAGAAGTCTCTAGAACTCAATCCAAATAATTCCACTGCTATGCTGAGAAAAGGAATATGTGAATACCATGAAAA
AAACTATGCTGCTGCCCTAGAAACTTTTACAGAAGGACAAAAATTAGATATAGAGACGGGGTTTCATCGTGTTGGCCAGGCTGGTCTCCA
ACTCTTGACCTCAAGTGATCCACCTGCCTTGGACTCCCAAAGTGCTGGGATTACAGGTGCAGATGCTAATTTCAGTGTCTGGATTAAAAG
GTGTCAAGAAGCTCAGAATGGCTCAGAATCTGAGGTGTGGACTCATCAGTCAAAAATCAAGTGCTCCATACTTGCTTGCAGTGCCTACGT
GGCTCTGGCTTTGGGTGATAACCTCATGGCTTTGAATCATGCAGATAAACTTCTTCAGCAGCCCAAGCTGTCAGGATCTCTTAAGTTTTT
GGGACATTTATATGCTGCAGAAGCCCTCATCTCTCTCGACAGAATATCTGATGCCATTACTCACTTGAACCCGGAGAATGTCACTGATGT
CTCCTTAGGGATCTCTTCAAATGAGCAGGACCAAGGATCAGACAAAGGTGAAAATGAAGCAATGGAATCCTCTGGTAAGCGGGCCCCTCA
GTGCTACCCCAGTTCCGTCAACTCTGCCAGGACTGTGATGCTGTTCAACCTTGGCAGCGCTTACTGCCTGAGGAGCGAATATGACAAAGC
CCGAAAGTGTCTCCACCAGGCGGCTTCAATGATCCATCCTAAAGAGGTGCCCCCTGAGGCCATCTTGCTGGCAGTCTACCTTGAACTGCA
GAATGGTAATACTCAGCTGGCCTTACAGATCATCAAAAGGAATCAGCTGCTCCCTGCAGTGAAAACACACTCTGAAGTGAGAAAGAAGCC
AGTGTTTCAGCCTGTCCACCCGATCCAGCCCATCCAAATGCCGGCTTTCACCACTGTGCAGAGAAAGTGATACTTCACTTTTGGAAAACT
GTTACCTGAGACCCAGGGGAGAATTTACTGGCCATTTTAGTTGTATCACAGCAGAATGAATAAAAGATGGTGAAGGCTGTTAATTTTGAG
TCAATTCTACCCCTGACATTTGGCCAAAAGCTTACTTAAAATTAAGGATTTACTAAGTCATCATCAGCTGTTTTTCTTAATTTCAGCCAG

>88012_88012_5_SUGT1-CNOT10_SUGT1_chr13_53238192_ENST00000343788_CNOT10_chr3_32800949_ENST00000328834_length(amino acids)=385AA_BP=0
MAAAAAGTATSQRFFQSFSDALIDEDPQAALEELTKALEQKPDDAQYYCQRAYCHILLGNYCVAVADAKKSLELNPNNSTAMLRKGICEY
HEKNYAAALETFTEGQKLDIETGFHRVGQAGLQLLTSSDPPALDSQSAGITGADANFSVWIKRCQEAQNGSESEVWTHQSKIKCSILACS
AYVALALGDNLMALNHADKLLQQPKLSGSLKFLGHLYAAEALISLDRISDAITHLNPENVTDVSLGISSNEQDQGSDKGENEAMESSGKR
APQCYPSSVNSARTVMLFNLGSAYCLRSEYDKARKCLHQAASMIHPKEVPPEAILLAVYLELQNGNTQLALQIIKRNQLLPAVKTHSEVR

--------------------------------------------------------------
>88012_88012_6_SUGT1-CNOT10_SUGT1_chr13_53238192_ENST00000343788_CNOT10_chr3_32800949_ENST00000331889_length(transcript)=1343nt_BP=600nt
CAGAAGTTTCCCCCTTGGGCGGTGGTGGAGGTGGTAACCGTGATAGTAGCAGCTCCGGCGGCAGCAACAGCGACTACGAGGGATGGCGGC
GGCTGCAGCAGGAACTGCAACATCCCAGAGGTTTTTCCAGAGCTTCTCGGATGCCCTAATCGACGAGGACCCCCAGGCGGCGTTAGAGGA
GCTGACTAAGGCTTTGGAACAGAAACCAGATGATGCACAGTATTATTGTCAAAGAGCTTATTGTCACATTCTTCTTGGGAATTACTGTGT
TGCTGTTGCTGATGCAAAGAAGTCTCTAGAACTCAATCCAAATAATTCCACTGCTATGCTGAGAAAAGGAATATGTGAATACCATGAAAA
AAACTATGCTGCTGCCCTAGAAACTTTTACAGAAGGACAAAAATTAGATATAGAGACGGGGTTTCATCGTGTTGGCCAGGCTGGTCTCCA
ACTCTTGACCTCAAGTGATCCACCTGCCTTGGACTCCCAAAGTGCTGGGATTACAGGTGCAGATGCTAATTTCAGTGTCTGGATTAAAAG
GTGTCAAGAAGCTCAGAATGGCTCAGAATCTGAGGTGTGGACTCATCAGTCAAAAATCAAGTGCTCCATACTTGCTTGCAGTGCCTACGT
GGCTCTGGCTTTGGGTGATAACCTCATGGCTTTGAATCATGCAGATAAACTTCTTCAGCAGCCCAAGCTGTCAGGATCTCTTAAGTTTTT
GGGACATTTATATGCTGCAGAAGCCCTCATCTCTCTCGACAGAATATCTGATGCCATTACTCACTTGAACCCGGAGAATGTCACTGATGT
CTCCTTAGGGATCTCTTCAAATGAGCAGGACCAAGGATCAGACAAAGGTGAAAATGAAGCAATGGAATCCTCTGGTAAGCGGGCCCCTCA
GTGCTACCCCAGTTCCGTCAACTCTGCCAGGACTGTGATGCTGTTCAACCTTGGCAGCGCTTACTGCCTGAGGAGCGAATATGACAAAGC
CCGAAAGTGTCTCCACCAGGCGGCTTCAATGATCCATCCTAAAGAGGTGCCCCCTGAGGCCATCTTGCTGGCAGTCTACCTTGAACTGCA
GAATGGTAATACTCAGCTGGCCTTACAGATCATCAAAAGGAATCAGCTGCTCCCTGCAGTGAAAACACACTCTGAAGTGAGAAAGAAGCC
AGTGTTTCAGCCTGTCCACCCGATCCAGCCCATCCAAATGCCGGCTTTCACCACTGTGCAGAGAAAGTGATACTTCACTTTTGGAAAACT

>88012_88012_6_SUGT1-CNOT10_SUGT1_chr13_53238192_ENST00000343788_CNOT10_chr3_32800949_ENST00000331889_length(amino acids)=385AA_BP=0
MAAAAAGTATSQRFFQSFSDALIDEDPQAALEELTKALEQKPDDAQYYCQRAYCHILLGNYCVAVADAKKSLELNPNNSTAMLRKGICEY
HEKNYAAALETFTEGQKLDIETGFHRVGQAGLQLLTSSDPPALDSQSAGITGADANFSVWIKRCQEAQNGSESEVWTHQSKIKCSILACS
AYVALALGDNLMALNHADKLLQQPKLSGSLKFLGHLYAAEALISLDRISDAITHLNPENVTDVSLGISSNEQDQGSDKGENEAMESSGKR
APQCYPSSVNSARTVMLFNLGSAYCLRSEYDKARKCLHQAASMIHPKEVPPEAILLAVYLELQNGNTQLALQIIKRNQLLPAVKTHSEVR

--------------------------------------------------------------
>88012_88012_7_SUGT1-CNOT10_SUGT1_chr13_53238192_ENST00000343788_CNOT10_chr3_32800949_ENST00000454516_length(transcript)=1341nt_BP=600nt
CAGAAGTTTCCCCCTTGGGCGGTGGTGGAGGTGGTAACCGTGATAGTAGCAGCTCCGGCGGCAGCAACAGCGACTACGAGGGATGGCGGC
GGCTGCAGCAGGAACTGCAACATCCCAGAGGTTTTTCCAGAGCTTCTCGGATGCCCTAATCGACGAGGACCCCCAGGCGGCGTTAGAGGA
GCTGACTAAGGCTTTGGAACAGAAACCAGATGATGCACAGTATTATTGTCAAAGAGCTTATTGTCACATTCTTCTTGGGAATTACTGTGT
TGCTGTTGCTGATGCAAAGAAGTCTCTAGAACTCAATCCAAATAATTCCACTGCTATGCTGAGAAAAGGAATATGTGAATACCATGAAAA
AAACTATGCTGCTGCCCTAGAAACTTTTACAGAAGGACAAAAATTAGATATAGAGACGGGGTTTCATCGTGTTGGCCAGGCTGGTCTCCA
ACTCTTGACCTCAAGTGATCCACCTGCCTTGGACTCCCAAAGTGCTGGGATTACAGGTGCAGATGCTAATTTCAGTGTCTGGATTAAAAG
GTGTCAAGAAGCTCAGAATGGCTCAGAATCTGAGGTGTGGACTCATCAGTCAAAAATCAAGTGCTCCATACTTGCTTGCAGTGCCTACGT
GGCTCTGGCTTTGGGTGATAACCTCATGGCTTTGAATCATGCAGATAAACTTCTTCAGCAGCCCAAGCTGTCAGGATCTCTTAAGTTTTT
GGGACATTTATATGCTGCAGAAGCCCTCATCTCTCTCGACAGAATATCTGATGCCATTACTCACTTGAACCCGGAGAATGTCACTGATGT
CTCCTTAGGGATCTCTTCAAATGAGCAGGACCAAGGATCAGACAAAGGTGAAAATGAAGCAATGGAATCCTCTGGTAAGCGGGCCCCTCA
GTGCTACCCCAGTTCCGTCAACTCTGCCAGGACTGTGATGCTGTTCAACCTTGGCAGCGCTTACTGCCTGAGGAGCGAATATGACAAAGC
CCGAAAGTGTCTCCACCAGGCGGCTTCAATGATCCATCCTAAAGAGGTGCCCCCTGAGGCCATCTTGCTGGCAGTCTACCTTGAACTGCA
GAATGGTAATACTCAGCTGGCCTTACAGATCATCAAAAGGAATCAGCTGCTCCCTGCAGTGAAAACACACTCTGAAGTGAGAAAGAAGCC
AGTGTTTCAGCCTGTCCACCCGATCCAGCCCATCCAAATGCCGGCTTTCACCACTGTGCAGAGAAAGTGATACTTCACTTTTGGAAAACT

>88012_88012_7_SUGT1-CNOT10_SUGT1_chr13_53238192_ENST00000343788_CNOT10_chr3_32800949_ENST00000454516_length(amino acids)=385AA_BP=0
MAAAAAGTATSQRFFQSFSDALIDEDPQAALEELTKALEQKPDDAQYYCQRAYCHILLGNYCVAVADAKKSLELNPNNSTAMLRKGICEY
HEKNYAAALETFTEGQKLDIETGFHRVGQAGLQLLTSSDPPALDSQSAGITGADANFSVWIKRCQEAQNGSESEVWTHQSKIKCSILACS
AYVALALGDNLMALNHADKLLQQPKLSGSLKFLGHLYAAEALISLDRISDAITHLNPENVTDVSLGISSNEQDQGSDKGENEAMESSGKR
APQCYPSSVNSARTVMLFNLGSAYCLRSEYDKARKCLHQAASMIHPKEVPPEAILLAVYLELQNGNTQLALQIIKRNQLLPAVKTHSEVR

--------------------------------------------------------------
>88012_88012_8_SUGT1-CNOT10_SUGT1_chr13_53238192_ENST00000343788_CNOT10_chr3_32800949_ENST00000538368_length(transcript)=1293nt_BP=600nt
CAGAAGTTTCCCCCTTGGGCGGTGGTGGAGGTGGTAACCGTGATAGTAGCAGCTCCGGCGGCAGCAACAGCGACTACGAGGGATGGCGGC
GGCTGCAGCAGGAACTGCAACATCCCAGAGGTTTTTCCAGAGCTTCTCGGATGCCCTAATCGACGAGGACCCCCAGGCGGCGTTAGAGGA
GCTGACTAAGGCTTTGGAACAGAAACCAGATGATGCACAGTATTATTGTCAAAGAGCTTATTGTCACATTCTTCTTGGGAATTACTGTGT
TGCTGTTGCTGATGCAAAGAAGTCTCTAGAACTCAATCCAAATAATTCCACTGCTATGCTGAGAAAAGGAATATGTGAATACCATGAAAA
AAACTATGCTGCTGCCCTAGAAACTTTTACAGAAGGACAAAAATTAGATATAGAGACGGGGTTTCATCGTGTTGGCCAGGCTGGTCTCCA
ACTCTTGACCTCAAGTGATCCACCTGCCTTGGACTCCCAAAGTGCTGGGATTACAGGTGCAGATGCTAATTTCAGTGTCTGGATTAAAAG
GTGTCAAGAAGCTCAGAATGGCTCAGAATCTGAGGTGTGGACTCATCAGTCAAAAATCAAGTGCTCCATACTTGCTTGCAGTGCCTACGT
GGCTCTGGCTTTGGGTGATAACCTCATGGCTTTGAATCATGCAGATAAACTTCTTCAGCAGCCCAAGCTGTCAGGATCTCTTAAGTTTTT
GGGACATTTATATGCTGCAGAAGCCCTCATCTCTCTCGACAGAATATCTGATGCCATTACTCACTTGAACCCGGAGAATGTCACTGATGT
CTCCTTAGGGATCTCTTCAAATGAGCAGGACCAAGGTTAATGAGGACATCTTTGATCAGAACTGGTCACTGTTTCCATTTCCCTCCTGTC
ATAATTCAGGATGTGTGGAAATTTAGGCATGGTGGTAATGAGAAGAAAGTTTTAGGTTGGCTTTCCACATTTTTGTCTGTACTTACTTTG
TAGCAGTTGTTTGCTAAGTAGACCTGAGAGTTAATGATCACATCATCTAAATTCTCACTTTTGAAAGGCTGGTACTGTTAGAATGGTTAA
TTTTGGTTCTGATACTATTTATTTGTTTTCCTTTGGAGTGATTCTAAAATCCATAGGGGAGTAAAAATATTGCATTCAAGAGTCAGTTTT
AGTCCAGGCGTGGTGGCTCACGCCTGTAATCCCAGCACTTTGGGAGGCTGTAGCAGGAGGGTCACTTGAGCCCAAGAGTTCAAGACCAGC

>88012_88012_8_SUGT1-CNOT10_SUGT1_chr13_53238192_ENST00000343788_CNOT10_chr3_32800949_ENST00000538368_length(amino acids)=255AA_BP=0
MAAAAAGTATSQRFFQSFSDALIDEDPQAALEELTKALEQKPDDAQYYCQRAYCHILLGNYCVAVADAKKSLELNPNNSTAMLRKGICEY
HEKNYAAALETFTEGQKLDIETGFHRVGQAGLQLLTSSDPPALDSQSAGITGADANFSVWIKRCQEAQNGSESEVWTHQSKIKCSILACS

--------------------------------------------------------------
>88012_88012_9_SUGT1-CNOT10_SUGT1_chr13_53238192_ENST00000535397_CNOT10_chr3_32800949_ENST00000328834_length(transcript)=1531nt_BP=627nt
GTTTCCCCCTTGGGCGGTGGTGGAGGTGGTAACCGTGATAGTAGCAGCTCCGGCGGCAGCAACAGCGACTACGAGGGATGGCGGCGGCTG
CAGCAGGAACTGCAACATCCCAGAGGTTTTTCCAGAGCTTCTCGGATGCCCTAATCGACGAGGACCCCCAGGCGGCGTTAGAGGAGCTGA
CTAAGGCTTTGGAACAGAAACCAGATGATGCACAGTATTATTGTCAAAGAGCTTATTGTCACATTCTTCTTGGGAATTACTGTGGGAAAA
ACTGAATACCTTGAGTAAAATTACATAGAAAATGTTAATGAGACAAGGAGGTGAATTTTGTGACACAGCTGTATTCATTGAAGAGCTTTA
AGAAGGAAGCTAAATGTTAAGCCAAAAGGAAGTTGCTGTTGCTGATGCAAAGAAGTCTCTAGAACTCAATCCAAATAATTCCACTGCTAT
GCTGAGAAAAGGAATATGTGAATACCATGAAAAAAACTATGCTGCTGCCCTAGAAACTTTTACAGAAGGACAAAAATTAGATAGTGCAGA
TGCTAATTTCAGTGTCTGGATTAAAAGGTGTCAAGAAGCTCAGAATGGCTCAGAATCTGAGGTGTGGACTCATCAGTCAAAAATCAAGTG
CTCCATACTTGCTTGCAGTGCCTACGTGGCTCTGGCTTTGGGTGATAACCTCATGGCTTTGAATCATGCAGATAAACTTCTTCAGCAGCC
CAAGCTGTCAGGATCTCTTAAGTTTTTGGGACATTTATATGCTGCAGAAGCCCTCATCTCTCTCGACAGAATATCTGATGCCATTACTCA
CTTGAACCCGGAGAATGTCACTGATGTCTCCTTAGGGATCTCTTCAAATGAGCAGGACCAAGGATCAGACAAAGGTGAAAATGAAGCAAT
GGAATCCTCTGGTAAGCGGGCCCCTCAGTGCTACCCCAGTTCCGTCAACTCTGCCAGGACTGTGATGCTGTTCAACCTTGGCAGCGCTTA
CTGCCTGAGGAGCGAATATGACAAAGCCCGAAAGTGTCTCCACCAGGCGGCTTCAATGATCCATCCTAAAGAGGTGCCCCCTGAGGCCAT
CTTGCTGGCAGTCTACCTTGAACTGCAGAATGGTAATACTCAGCTGGCCTTACAGATCATCAAAAGGAATCAGCTGCTCCCTGCAGTGAA
AACACACTCTGAAGTGAGAAAGAAGCCAGTGTTTCAGCCTGTCCACCCGATCCAGCCCATCCAAATGCCGGCTTTCACCACTGTGCAGAG
AAAGTGATACTTCACTTTTGGAAAACTGTTACCTGAGACCCAGGGGAGAATTTACTGGCCATTTTAGTTGTATCACAGCAGAATGAATAA
AAGATGGTGAAGGCTGTTAATTTTGAGTCAATTCTACCCCTGACATTTGGCCAAAAGCTTACTTAAAATTAAGGATTTACTAAGTCATCA
TCAGCTGTTTTTCTTAATTTCAGCCAGACTATTAATTTTGAGCCATTATGTAATATATGCCATAGGCAATTAAAACATAATTTTATCAGA

>88012_88012_9_SUGT1-CNOT10_SUGT1_chr13_53238192_ENST00000535397_CNOT10_chr3_32800949_ENST00000328834_length(amino acids)=297AA_BP=6
MLSQKEVAVADAKKSLELNPNNSTAMLRKGICEYHEKNYAAALETFTEGQKLDSADANFSVWIKRCQEAQNGSESEVWTHQSKIKCSILA
CSAYVALALGDNLMALNHADKLLQQPKLSGSLKFLGHLYAAEALISLDRISDAITHLNPENVTDVSLGISSNEQDQGSDKGENEAMESSG
KRAPQCYPSSVNSARTVMLFNLGSAYCLRSEYDKARKCLHQAASMIHPKEVPPEAILLAVYLELQNGNTQLALQIIKRNQLLPAVKTHSE

--------------------------------------------------------------
>88012_88012_10_SUGT1-CNOT10_SUGT1_chr13_53238192_ENST00000535397_CNOT10_chr3_32800949_ENST00000331889_length(transcript)=1370nt_BP=627nt
GTTTCCCCCTTGGGCGGTGGTGGAGGTGGTAACCGTGATAGTAGCAGCTCCGGCGGCAGCAACAGCGACTACGAGGGATGGCGGCGGCTG
CAGCAGGAACTGCAACATCCCAGAGGTTTTTCCAGAGCTTCTCGGATGCCCTAATCGACGAGGACCCCCAGGCGGCGTTAGAGGAGCTGA
CTAAGGCTTTGGAACAGAAACCAGATGATGCACAGTATTATTGTCAAAGAGCTTATTGTCACATTCTTCTTGGGAATTACTGTGGGAAAA
ACTGAATACCTTGAGTAAAATTACATAGAAAATGTTAATGAGACAAGGAGGTGAATTTTGTGACACAGCTGTATTCATTGAAGAGCTTTA
AGAAGGAAGCTAAATGTTAAGCCAAAAGGAAGTTGCTGTTGCTGATGCAAAGAAGTCTCTAGAACTCAATCCAAATAATTCCACTGCTAT
GCTGAGAAAAGGAATATGTGAATACCATGAAAAAAACTATGCTGCTGCCCTAGAAACTTTTACAGAAGGACAAAAATTAGATAGTGCAGA
TGCTAATTTCAGTGTCTGGATTAAAAGGTGTCAAGAAGCTCAGAATGGCTCAGAATCTGAGGTGTGGACTCATCAGTCAAAAATCAAGTG
CTCCATACTTGCTTGCAGTGCCTACGTGGCTCTGGCTTTGGGTGATAACCTCATGGCTTTGAATCATGCAGATAAACTTCTTCAGCAGCC
CAAGCTGTCAGGATCTCTTAAGTTTTTGGGACATTTATATGCTGCAGAAGCCCTCATCTCTCTCGACAGAATATCTGATGCCATTACTCA
CTTGAACCCGGAGAATGTCACTGATGTCTCCTTAGGGATCTCTTCAAATGAGCAGGACCAAGGATCAGACAAAGGTGAAAATGAAGCAAT
GGAATCCTCTGGTAAGCGGGCCCCTCAGTGCTACCCCAGTTCCGTCAACTCTGCCAGGACTGTGATGCTGTTCAACCTTGGCAGCGCTTA
CTGCCTGAGGAGCGAATATGACAAAGCCCGAAAGTGTCTCCACCAGGCGGCTTCAATGATCCATCCTAAAGAGGTGCCCCCTGAGGCCAT
CTTGCTGGCAGTCTACCTTGAACTGCAGAATGGTAATACTCAGCTGGCCTTACAGATCATCAAAAGGAATCAGCTGCTCCCTGCAGTGAA
AACACACTCTGAAGTGAGAAAGAAGCCAGTGTTTCAGCCTGTCCACCCGATCCAGCCCATCCAAATGCCGGCTTTCACCACTGTGCAGAG
AAAGTGATACTTCACTTTTGGAAAACTGTTACCTGAGACCCAGGGGAGAATTTACTGGCCATTTTAGTTGTATCACAGCAGAATGAATAA

>88012_88012_10_SUGT1-CNOT10_SUGT1_chr13_53238192_ENST00000535397_CNOT10_chr3_32800949_ENST00000331889_length(amino acids)=297AA_BP=6
MLSQKEVAVADAKKSLELNPNNSTAMLRKGICEYHEKNYAAALETFTEGQKLDSADANFSVWIKRCQEAQNGSESEVWTHQSKIKCSILA
CSAYVALALGDNLMALNHADKLLQQPKLSGSLKFLGHLYAAEALISLDRISDAITHLNPENVTDVSLGISSNEQDQGSDKGENEAMESSG
KRAPQCYPSSVNSARTVMLFNLGSAYCLRSEYDKARKCLHQAASMIHPKEVPPEAILLAVYLELQNGNTQLALQIIKRNQLLPAVKTHSE

--------------------------------------------------------------
>88012_88012_11_SUGT1-CNOT10_SUGT1_chr13_53238192_ENST00000535397_CNOT10_chr3_32800949_ENST00000454516_length(transcript)=1368nt_BP=627nt
GTTTCCCCCTTGGGCGGTGGTGGAGGTGGTAACCGTGATAGTAGCAGCTCCGGCGGCAGCAACAGCGACTACGAGGGATGGCGGCGGCTG
CAGCAGGAACTGCAACATCCCAGAGGTTTTTCCAGAGCTTCTCGGATGCCCTAATCGACGAGGACCCCCAGGCGGCGTTAGAGGAGCTGA
CTAAGGCTTTGGAACAGAAACCAGATGATGCACAGTATTATTGTCAAAGAGCTTATTGTCACATTCTTCTTGGGAATTACTGTGGGAAAA
ACTGAATACCTTGAGTAAAATTACATAGAAAATGTTAATGAGACAAGGAGGTGAATTTTGTGACACAGCTGTATTCATTGAAGAGCTTTA
AGAAGGAAGCTAAATGTTAAGCCAAAAGGAAGTTGCTGTTGCTGATGCAAAGAAGTCTCTAGAACTCAATCCAAATAATTCCACTGCTAT
GCTGAGAAAAGGAATATGTGAATACCATGAAAAAAACTATGCTGCTGCCCTAGAAACTTTTACAGAAGGACAAAAATTAGATAGTGCAGA
TGCTAATTTCAGTGTCTGGATTAAAAGGTGTCAAGAAGCTCAGAATGGCTCAGAATCTGAGGTGTGGACTCATCAGTCAAAAATCAAGTG
CTCCATACTTGCTTGCAGTGCCTACGTGGCTCTGGCTTTGGGTGATAACCTCATGGCTTTGAATCATGCAGATAAACTTCTTCAGCAGCC
CAAGCTGTCAGGATCTCTTAAGTTTTTGGGACATTTATATGCTGCAGAAGCCCTCATCTCTCTCGACAGAATATCTGATGCCATTACTCA
CTTGAACCCGGAGAATGTCACTGATGTCTCCTTAGGGATCTCTTCAAATGAGCAGGACCAAGGATCAGACAAAGGTGAAAATGAAGCAAT
GGAATCCTCTGGTAAGCGGGCCCCTCAGTGCTACCCCAGTTCCGTCAACTCTGCCAGGACTGTGATGCTGTTCAACCTTGGCAGCGCTTA
CTGCCTGAGGAGCGAATATGACAAAGCCCGAAAGTGTCTCCACCAGGCGGCTTCAATGATCCATCCTAAAGAGGTGCCCCCTGAGGCCAT
CTTGCTGGCAGTCTACCTTGAACTGCAGAATGGTAATACTCAGCTGGCCTTACAGATCATCAAAAGGAATCAGCTGCTCCCTGCAGTGAA
AACACACTCTGAAGTGAGAAAGAAGCCAGTGTTTCAGCCTGTCCACCCGATCCAGCCCATCCAAATGCCGGCTTTCACCACTGTGCAGAG
AAAGTGATACTTCACTTTTGGAAAACTGTTACCTGAGACCCAGGGGAGAATTTACTGGCCATTTTAGTTGTATCACAGCAGAATGAATAA

>88012_88012_11_SUGT1-CNOT10_SUGT1_chr13_53238192_ENST00000535397_CNOT10_chr3_32800949_ENST00000454516_length(amino acids)=297AA_BP=6
MLSQKEVAVADAKKSLELNPNNSTAMLRKGICEYHEKNYAAALETFTEGQKLDSADANFSVWIKRCQEAQNGSESEVWTHQSKIKCSILA
CSAYVALALGDNLMALNHADKLLQQPKLSGSLKFLGHLYAAEALISLDRISDAITHLNPENVTDVSLGISSNEQDQGSDKGENEAMESSG
KRAPQCYPSSVNSARTVMLFNLGSAYCLRSEYDKARKCLHQAASMIHPKEVPPEAILLAVYLELQNGNTQLALQIIKRNQLLPAVKTHSE

--------------------------------------------------------------
>88012_88012_12_SUGT1-CNOT10_SUGT1_chr13_53238192_ENST00000535397_CNOT10_chr3_32800949_ENST00000538368_length(transcript)=1320nt_BP=627nt
GTTTCCCCCTTGGGCGGTGGTGGAGGTGGTAACCGTGATAGTAGCAGCTCCGGCGGCAGCAACAGCGACTACGAGGGATGGCGGCGGCTG
CAGCAGGAACTGCAACATCCCAGAGGTTTTTCCAGAGCTTCTCGGATGCCCTAATCGACGAGGACCCCCAGGCGGCGTTAGAGGAGCTGA
CTAAGGCTTTGGAACAGAAACCAGATGATGCACAGTATTATTGTCAAAGAGCTTATTGTCACATTCTTCTTGGGAATTACTGTGGGAAAA
ACTGAATACCTTGAGTAAAATTACATAGAAAATGTTAATGAGACAAGGAGGTGAATTTTGTGACACAGCTGTATTCATTGAAGAGCTTTA
AGAAGGAAGCTAAATGTTAAGCCAAAAGGAAGTTGCTGTTGCTGATGCAAAGAAGTCTCTAGAACTCAATCCAAATAATTCCACTGCTAT
GCTGAGAAAAGGAATATGTGAATACCATGAAAAAAACTATGCTGCTGCCCTAGAAACTTTTACAGAAGGACAAAAATTAGATAGTGCAGA
TGCTAATTTCAGTGTCTGGATTAAAAGGTGTCAAGAAGCTCAGAATGGCTCAGAATCTGAGGTGTGGACTCATCAGTCAAAAATCAAGTG
CTCCATACTTGCTTGCAGTGCCTACGTGGCTCTGGCTTTGGGTGATAACCTCATGGCTTTGAATCATGCAGATAAACTTCTTCAGCAGCC
CAAGCTGTCAGGATCTCTTAAGTTTTTGGGACATTTATATGCTGCAGAAGCCCTCATCTCTCTCGACAGAATATCTGATGCCATTACTCA
CTTGAACCCGGAGAATGTCACTGATGTCTCCTTAGGGATCTCTTCAAATGAGCAGGACCAAGGTTAATGAGGACATCTTTGATCAGAACT
GGTCACTGTTTCCATTTCCCTCCTGTCATAATTCAGGATGTGTGGAAATTTAGGCATGGTGGTAATGAGAAGAAAGTTTTAGGTTGGCTT
TCCACATTTTTGTCTGTACTTACTTTGTAGCAGTTGTTTGCTAAGTAGACCTGAGAGTTAATGATCACATCATCTAAATTCTCACTTTTG
AAAGGCTGGTACTGTTAGAATGGTTAATTTTGGTTCTGATACTATTTATTTGTTTTCCTTTGGAGTGATTCTAAAATCCATAGGGGAGTA
AAAATATTGCATTCAAGAGTCAGTTTTAGTCCAGGCGTGGTGGCTCACGCCTGTAATCCCAGCACTTTGGGAGGCTGTAGCAGGAGGGTC

>88012_88012_12_SUGT1-CNOT10_SUGT1_chr13_53238192_ENST00000535397_CNOT10_chr3_32800949_ENST00000538368_length(amino acids)=167AA_BP=6
MLSQKEVAVADAKKSLELNPNNSTAMLRKGICEYHEKNYAAALETFTEGQKLDSADANFSVWIKRCQEAQNGSESEVWTHQSKIKCSILA

--------------------------------------------------------------

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Fusion Gene PPI Analysis for SUGT1-CNOT10


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for SUGT1-CNOT10


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for SUGT1-CNOT10


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource