|
||||||
|
 | Fusion Gene Summary |
| Fusion Gene ORF analysis |
| Fusion Genomic Features |
| Fusion Protein Features |
| Fusion Gene Sequence |
| Fusion Gene PPI analysis |
| Related Drugs |
| Related Diseases |
Fusion gene:SULF1-TERF1 (FusionGDB2 ID:88037) |
Fusion Gene Summary for SULF1-TERF1 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: SULF1-TERF1 | Fusion gene ID: 88037 | Hgene | Tgene | Gene symbol | SULF1 | TERF1 | Gene ID | 23213 | 7013 |
| Gene name | sulfatase 1 | telomeric repeat binding factor 1 | |
| Synonyms | SULF-1 | PIN2|TRBF1|TRF|TRF1|hTRF1-AS|t-TRF1 | |
| Cytomap | 8q13.2-q13.3 | 8q21.11 | |
| Type of gene | protein-coding | protein-coding | |
| Description | extracellular sulfatase Sulf-1sulfatase FP | telomeric repeat-binding factor 1NIMA-interacting protein 2TTAGGG repeat-binding factor 1telomeric protein Pin2/TRF1telomeric repeat binding factor (NIMA-interacting) 1 | |
| Modification date | 20200313 | 20200327 | |
| UniProtAcc | . | TINF2 | |
| Ensembl transtripts involved in fusion gene | ENST00000521946, ENST00000260128, ENST00000402687, ENST00000419716, ENST00000458141, | ENST00000276602, ENST00000276603, ENST00000520783, | |
| Fusion gene scores | * DoF score | 13 X 15 X 5=975 | 4 X 4 X 3=48 |
| # samples | 16 | 5 | |
| ** MAII score | log2(16/975*10)=-2.60733031374961 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(5/48*10)=0.0588936890535686 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | |
| Context | PubMed: SULF1 [Title/Abstract] AND TERF1 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Most frequent breakpoint | SULF1(70533486)-TERF1(73958196), # samples:1 SULF1(70533486)-TERF1(73958195), # samples:1 | ||
| Anticipated loss of major functional domain due to fusion event. | SULF1-TERF1 seems lost the major protein functional domain in Tgene partner, which is a transcription factor due to the frame-shifted ORF. | ||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Hgene | SULF1 | GO:0001937 | negative regulation of endothelial cell proliferation | 16778174 |
| Hgene | SULF1 | GO:0016525 | negative regulation of angiogenesis | 16778174 |
| Hgene | SULF1 | GO:0030177 | positive regulation of Wnt signaling pathway | 19520866 |
| Hgene | SULF1 | GO:0030201 | heparan sulfate proteoglycan metabolic process | 18687675|19666466|19822709 |
| Hgene | SULF1 | GO:0048010 | vascular endothelial growth factor receptor signaling pathway | 16778174 |
| Tgene | TERF1 | GO:0007004 | telomere maintenance via telomerase | 23685356 |
| Tgene | TERF1 | GO:0008156 | negative regulation of DNA replication | 11327863 |
| Tgene | TERF1 | GO:1905778 | negative regulation of exonuclease activity | 15200954 |
| Tgene | TERF1 | GO:1905839 | negative regulation of telomeric D-loop disassembly | 15200954 |
| Fusion gene breakpoints across SULF1 (5'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
 |
| Fusion gene breakpoints across TERF1 (3'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
 |
| Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Source | Disease | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| ChimerDB4 | SARC | TCGA-DX-A7ET-01A | SULF1 | chr8 | 70533486 | + | TERF1 | chr8 | 73958196 | + |
| ChimerDB4 | SARC | TCGA-DX-A7ET | SULF1 | chr8 | 70533486 | + | TERF1 | chr8 | 73958195 | + |
Top |
Fusion Gene ORF analysis for SULF1-TERF1 |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| 3UTR-3CDS | ENST00000521946 | ENST00000276602 | SULF1 | chr8 | 70533486 | + | TERF1 | chr8 | 73958196 | + |
| 3UTR-3CDS | ENST00000521946 | ENST00000276602 | SULF1 | chr8 | 70533486 | + | TERF1 | chr8 | 73958195 | + |
| 3UTR-3CDS | ENST00000521946 | ENST00000276603 | SULF1 | chr8 | 70533486 | + | TERF1 | chr8 | 73958196 | + |
| 3UTR-3CDS | ENST00000521946 | ENST00000276603 | SULF1 | chr8 | 70533486 | + | TERF1 | chr8 | 73958195 | + |
| 3UTR-intron | ENST00000521946 | ENST00000520783 | SULF1 | chr8 | 70533486 | + | TERF1 | chr8 | 73958196 | + |
| 3UTR-intron | ENST00000521946 | ENST00000520783 | SULF1 | chr8 | 70533486 | + | TERF1 | chr8 | 73958195 | + |
| 5CDS-intron | ENST00000260128 | ENST00000520783 | SULF1 | chr8 | 70533486 | + | TERF1 | chr8 | 73958196 | + |
| 5CDS-intron | ENST00000260128 | ENST00000520783 | SULF1 | chr8 | 70533486 | + | TERF1 | chr8 | 73958195 | + |
| 5CDS-intron | ENST00000402687 | ENST00000520783 | SULF1 | chr8 | 70533486 | + | TERF1 | chr8 | 73958196 | + |
| 5CDS-intron | ENST00000402687 | ENST00000520783 | SULF1 | chr8 | 70533486 | + | TERF1 | chr8 | 73958195 | + |
| 5CDS-intron | ENST00000419716 | ENST00000520783 | SULF1 | chr8 | 70533486 | + | TERF1 | chr8 | 73958196 | + |
| 5CDS-intron | ENST00000419716 | ENST00000520783 | SULF1 | chr8 | 70533486 | + | TERF1 | chr8 | 73958195 | + |
| 5CDS-intron | ENST00000458141 | ENST00000520783 | SULF1 | chr8 | 70533486 | + | TERF1 | chr8 | 73958196 | + |
| 5CDS-intron | ENST00000458141 | ENST00000520783 | SULF1 | chr8 | 70533486 | + | TERF1 | chr8 | 73958195 | + |
| Frame-shift | ENST00000260128 | ENST00000276603 | SULF1 | chr8 | 70533486 | + | TERF1 | chr8 | 73958196 | + |
| Frame-shift | ENST00000260128 | ENST00000276603 | SULF1 | chr8 | 70533486 | + | TERF1 | chr8 | 73958195 | + |
| Frame-shift | ENST00000402687 | ENST00000276603 | SULF1 | chr8 | 70533486 | + | TERF1 | chr8 | 73958196 | + |
| Frame-shift | ENST00000402687 | ENST00000276603 | SULF1 | chr8 | 70533486 | + | TERF1 | chr8 | 73958195 | + |
| Frame-shift | ENST00000419716 | ENST00000276603 | SULF1 | chr8 | 70533486 | + | TERF1 | chr8 | 73958196 | + |
| Frame-shift | ENST00000419716 | ENST00000276603 | SULF1 | chr8 | 70533486 | + | TERF1 | chr8 | 73958195 | + |
| Frame-shift | ENST00000458141 | ENST00000276603 | SULF1 | chr8 | 70533486 | + | TERF1 | chr8 | 73958196 | + |
| Frame-shift | ENST00000458141 | ENST00000276603 | SULF1 | chr8 | 70533486 | + | TERF1 | chr8 | 73958195 | + |
| In-frame | ENST00000260128 | ENST00000276602 | SULF1 | chr8 | 70533486 | + | TERF1 | chr8 | 73958196 | + |
| In-frame | ENST00000260128 | ENST00000276602 | SULF1 | chr8 | 70533486 | + | TERF1 | chr8 | 73958195 | + |
| In-frame | ENST00000402687 | ENST00000276602 | SULF1 | chr8 | 70533486 | + | TERF1 | chr8 | 73958196 | + |
| In-frame | ENST00000402687 | ENST00000276602 | SULF1 | chr8 | 70533486 | + | TERF1 | chr8 | 73958195 | + |
| In-frame | ENST00000419716 | ENST00000276602 | SULF1 | chr8 | 70533486 | + | TERF1 | chr8 | 73958196 | + |
| In-frame | ENST00000419716 | ENST00000276602 | SULF1 | chr8 | 70533486 | + | TERF1 | chr8 | 73958195 | + |
| In-frame | ENST00000458141 | ENST00000276602 | SULF1 | chr8 | 70533486 | + | TERF1 | chr8 | 73958196 | + |
| In-frame | ENST00000458141 | ENST00000276602 | SULF1 | chr8 | 70533486 | + | TERF1 | chr8 | 73958195 | + |
| ORFfinder result based on the fusion transcript sequence of in-frame fusion genes. |
| Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | Seq length (transcript) | BP loci (transcript) | Predicted start (transcript) | Predicted stop (transcript) | Seq length (amino acids) |
| ENST00000260128 | SULF1 | chr8 | 70533486 | + | ENST00000276602 | TERF1 | chr8 | 73958196 | + | 4473 | 2311 | 717 | 2381 | 554 |
| ENST00000458141 | SULF1 | chr8 | 70533486 | + | ENST00000276602 | TERF1 | chr8 | 73958196 | + | 4311 | 2149 | 555 | 2219 | 554 |
| ENST00000402687 | SULF1 | chr8 | 70533486 | + | ENST00000276602 | TERF1 | chr8 | 73958196 | + | 4511 | 2349 | 755 | 2419 | 554 |
| ENST00000419716 | SULF1 | chr8 | 70533486 | + | ENST00000276602 | TERF1 | chr8 | 73958196 | + | 4317 | 2155 | 561 | 2225 | 554 |
| ENST00000260128 | SULF1 | chr8 | 70533486 | + | ENST00000276602 | TERF1 | chr8 | 73958195 | + | 4473 | 2311 | 717 | 2381 | 554 |
| ENST00000458141 | SULF1 | chr8 | 70533486 | + | ENST00000276602 | TERF1 | chr8 | 73958195 | + | 4311 | 2149 | 555 | 2219 | 554 |
| ENST00000402687 | SULF1 | chr8 | 70533486 | + | ENST00000276602 | TERF1 | chr8 | 73958195 | + | 4511 | 2349 | 755 | 2419 | 554 |
| ENST00000419716 | SULF1 | chr8 | 70533486 | + | ENST00000276602 | TERF1 | chr8 | 73958195 | + | 4317 | 2155 | 561 | 2225 | 554 |
| DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated. |
| Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | No-coding score | Coding score |
| ENST00000260128 | ENST00000276602 | SULF1 | chr8 | 70533486 | + | TERF1 | chr8 | 73958196 | + | 0.000289402 | 0.9997106 |
| ENST00000458141 | ENST00000276602 | SULF1 | chr8 | 70533486 | + | TERF1 | chr8 | 73958196 | + | 0.000294689 | 0.99970526 |
| ENST00000402687 | ENST00000276602 | SULF1 | chr8 | 70533486 | + | TERF1 | chr8 | 73958196 | + | 0.000290324 | 0.99970967 |
| ENST00000419716 | ENST00000276602 | SULF1 | chr8 | 70533486 | + | TERF1 | chr8 | 73958196 | + | 0.000312414 | 0.99968755 |
| ENST00000260128 | ENST00000276602 | SULF1 | chr8 | 70533486 | + | TERF1 | chr8 | 73958195 | + | 0.000289402 | 0.9997106 |
| ENST00000458141 | ENST00000276602 | SULF1 | chr8 | 70533486 | + | TERF1 | chr8 | 73958195 | + | 0.000294689 | 0.99970526 |
| ENST00000402687 | ENST00000276602 | SULF1 | chr8 | 70533486 | + | TERF1 | chr8 | 73958195 | + | 0.000290324 | 0.99970967 |
| ENST00000419716 | ENST00000276602 | SULF1 | chr8 | 70533486 | + | TERF1 | chr8 | 73958195 | + | 0.000312414 | 0.99968755 |
Top |
Fusion Genomic Features for SULF1-TERF1 |
| FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints. |
| Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | 1-p | p (fusion gene breakpoint) |
| SULF1 | chr8 | 70533486 | + | TERF1 | chr8 | 73958195 | + | 0.000536191 | 0.99946386 |
| SULF1 | chr8 | 70533486 | + | TERF1 | chr8 | 73958195 | + | 0.000536191 | 0.99946386 |
| SULF1 | chr8 | 70533486 | + | TERF1 | chr8 | 73958195 | + | 0.000536191 | 0.99946386 |
| SULF1 | chr8 | 70533486 | + | TERF1 | chr8 | 73958195 | + | 0.000536191 | 0.99946386 |
| Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page. |
 |
| Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page. |
 |
Top |
Fusion Protein Features for SULF1-TERF1 |
| Four levels of functional features of fusion genes Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr8:70533486/chr8:73958196) - FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels. - How to search 1. Put your fusion gene symbol. 2. Press the tab key until there will be shown the breakpoint information filled. 4. Go down and press 'Search' tab twice. 4. Go down to have the hyperlink of the search result. 5. Click the hyperlink. 6. See the FGviewer result for your fusion gene. |
 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| . | TERF1 |
| FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}. | 451 |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Tgene | TERF1 | chr8:70533486 | chr8:73958195 | ENST00000276602 | 7 | 9 | 403_428 | 361 | 420.0 | DNA binding | H-T-H motif | |
| Tgene | TERF1 | chr8:70533486 | chr8:73958195 | ENST00000276603 | 8 | 10 | 403_428 | 381 | 440.0 | DNA binding | H-T-H motif | |
| Tgene | TERF1 | chr8:70533486 | chr8:73958196 | ENST00000276602 | 7 | 9 | 403_428 | 361 | 420.0 | DNA binding | H-T-H motif | |
| Tgene | TERF1 | chr8:70533486 | chr8:73958196 | ENST00000276603 | 8 | 10 | 403_428 | 381 | 440.0 | DNA binding | H-T-H motif | |
| Tgene | TERF1 | chr8:70533486 | chr8:73958195 | ENST00000276602 | 7 | 9 | 375_432 | 361 | 420.0 | Domain | HTH myb-type | |
| Tgene | TERF1 | chr8:70533486 | chr8:73958196 | ENST00000276602 | 7 | 9 | 375_432 | 361 | 420.0 | Domain | HTH myb-type |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Tgene | TERF1 | chr8:70533486 | chr8:73958195 | ENST00000276602 | 7 | 9 | 2_71 | 361 | 420.0 | Compositional bias | Note=Asp/Glu-rich (acidic) | |
| Tgene | TERF1 | chr8:70533486 | chr8:73958195 | ENST00000276602 | 7 | 9 | 55_62 | 361 | 420.0 | Compositional bias | Note=Poly-Glu | |
| Tgene | TERF1 | chr8:70533486 | chr8:73958195 | ENST00000276603 | 8 | 10 | 2_71 | 381 | 440.0 | Compositional bias | Note=Asp/Glu-rich (acidic) | |
| Tgene | TERF1 | chr8:70533486 | chr8:73958195 | ENST00000276603 | 8 | 10 | 55_62 | 381 | 440.0 | Compositional bias | Note=Poly-Glu | |
| Tgene | TERF1 | chr8:70533486 | chr8:73958196 | ENST00000276602 | 7 | 9 | 2_71 | 361 | 420.0 | Compositional bias | Note=Asp/Glu-rich (acidic) | |
| Tgene | TERF1 | chr8:70533486 | chr8:73958196 | ENST00000276602 | 7 | 9 | 55_62 | 361 | 420.0 | Compositional bias | Note=Poly-Glu | |
| Tgene | TERF1 | chr8:70533486 | chr8:73958196 | ENST00000276603 | 8 | 10 | 2_71 | 381 | 440.0 | Compositional bias | Note=Asp/Glu-rich (acidic) | |
| Tgene | TERF1 | chr8:70533486 | chr8:73958196 | ENST00000276603 | 8 | 10 | 55_62 | 381 | 440.0 | Compositional bias | Note=Poly-Glu | |
| Tgene | TERF1 | chr8:70533486 | chr8:73958195 | ENST00000276603 | 8 | 10 | 375_432 | 381 | 440.0 | Domain | HTH myb-type | |
| Tgene | TERF1 | chr8:70533486 | chr8:73958196 | ENST00000276603 | 8 | 10 | 375_432 | 381 | 440.0 | Domain | HTH myb-type | |
| Tgene | TERF1 | chr8:70533486 | chr8:73958195 | ENST00000276602 | 7 | 9 | 337_356 | 361 | 420.0 | Motif | Nuclear localization signal | |
| Tgene | TERF1 | chr8:70533486 | chr8:73958195 | ENST00000276603 | 8 | 10 | 337_356 | 381 | 440.0 | Motif | Nuclear localization signal | |
| Tgene | TERF1 | chr8:70533486 | chr8:73958196 | ENST00000276602 | 7 | 9 | 337_356 | 361 | 420.0 | Motif | Nuclear localization signal | |
| Tgene | TERF1 | chr8:70533486 | chr8:73958196 | ENST00000276603 | 8 | 10 | 337_356 | 381 | 440.0 | Motif | Nuclear localization signal | |
| Tgene | TERF1 | chr8:70533486 | chr8:73958195 | ENST00000276602 | 7 | 9 | 58_268 | 361 | 420.0 | Region | Note=TRFH dimerization | |
| Tgene | TERF1 | chr8:70533486 | chr8:73958195 | ENST00000276603 | 8 | 10 | 58_268 | 381 | 440.0 | Region | Note=TRFH dimerization | |
| Tgene | TERF1 | chr8:70533486 | chr8:73958196 | ENST00000276602 | 7 | 9 | 58_268 | 361 | 420.0 | Region | Note=TRFH dimerization | |
| Tgene | TERF1 | chr8:70533486 | chr8:73958196 | ENST00000276603 | 8 | 10 | 58_268 | 381 | 440.0 | Region | Note=TRFH dimerization |
Top |
Fusion Gene Sequence for SULF1-TERF1 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones. |
| >88037_88037_1_SULF1-TERF1_SULF1_chr8_70533486_ENST00000260128_TERF1_chr8_73958195_ENST00000276602_length(transcript)=4473nt_BP=2311nt AGGTTACTTGACTGGGAGTTCTCAGACCTCCAGTTTCAGCCCTGCCCTCAGCCTCCAATCCGTAAGAGACACCCAGCCCCAGCAATTGGA TTGGGCAGCCCGTCTTGACACACCACTGTGCTGAGTGCTTGAGGACGTGTTTCAACAGATGGTTGGGGTTAGTGTGTGTCATCACATTCG AGTGGGGATTAAGAGAAGGAAGGCTGCCTTGCTGGAGCTGTGTGGTCTTCTCCAAGTGAGAGTCGCAGGCAATAGAACTACTTTGCTTTT GGAGGAAAAGGAGGAATTCATTTTCAGCAGACACAAGAAAAGCAGTTTTTTTTTCAGGGATTCTTCACTTCTCTTGAACAAGGAACTCAC TCAGAGACTAACACAAAGGAAGTAATTTCTTACCTGGTCATTATTTAGTCTACAATAAGTTCATCCTTCTTCAGTGTGACCAGTAAATTC TTCCCATACTCTTGAAGAGAGCATAATTGGAATGGAGAGGTGCTGACGGCCACCCACCATCATCTAAAGAAGATAAACTTGGCAAATGAC ATGCAGGTTCTTCAAGGCAGAATAATTGCAGAAAATCTTCAAAGGACCCTATCTGCAGATGTTCTGAATACCTCTGAGAATAGAGATTGA TTATTCAACCAGGATACCTAATTCAAGAACTCCAGAAATCAGGAGACGGAGACATTTTGTCAGTTTTGCAACATTGGACCAAATACAATG AAGTATTCTTGCTGTGCTCTGGTTTTGGCTGTCCTGGGCACAGAATTGCTGGGAAGCCTCTGTTCGACTGTCAGATCCCCGAGGTTCAGA GGACGGATACAGCAGGAACGAAAAAACATCCGACCCAACATTATTCTTGTGCTTACCGATGATCAAGATGTGGAGCTGGGGTCCCTGCAA GTCATGAACAAAACGAGAAAGATTATGGAACATGGGGGGGCCACCTTCATCAATGCCTTTGTGACTACACCCATGTGCTGCCCGTCACGG TCCTCCATGCTCACCGGGAAGTATGTGCACAATCACAATGTCTACACCAACAACGAGAACTGCTCTTCCCCCTCGTGGCAGGCCATGCAT GAGCCTCGGACTTTTGCTGTATATCTTAACAACACTGGCTACAGAACAGCCTTTTTTGGAAAATACCTCAATGAATATAATGGCAGCTAC ATCCCCCCTGGGTGGCGAGAATGGCTTGGATTAATCAAGAATTCTCGCTTCTATAATTACACTGTTTGTCGCAATGGCATCAAAGAAAAG CATGGATTTGATTATGCAAAGGACTACTTCACAGACTTAATCACTAACGAGAGCATTAATTACTTCAAAATGTCTAAGAGAATGTATCCC CATAGGCCCGTTATGATGGTGATCAGCCACGCTGCGCCCCACGGCCCCGAGGACTCAGCCCCACAGTTTTCTAAACTGTACCCCAATGCT TCCCAACACATAACTCCTAGTTATAACTATGCACCAAATATGGATAAACACTGGATTATGCAGTACACAGGACCAATGCTGCCCATCCAC ATGGAATTTACAAACATTCTACAGCGCAAAAGGCTCCAGACTTTGATGTCAGTGGATGATTCTGTGGAGAGGCTGTATAACATGCTCGTG GAGACGGGGGAGCTGGAGAATACTTACATCATTTACACCGCCGACCATGGTTACCATATTGGGCAGTTTGGACTGGTCAAGGGGAAATCC ATGCCATATGACTTTGATATTCGTGTGCCTTTTTTTATTCGTGGTCCAAGTGTAGAACCAGGATCAATAGTCCCACAGATCGTTCTCAAC ATTGACTTGGCCCCCACGATCCTGGATATTGCTGGGCTCGACACACCTCCTGATGTGGACGGCAAGTCTGTCCTCAAACTTCTGGACCCA GAAAAGCCAGGTAACAGGTTTCGAACAAACAAGAAGGCCAAAATTTGGCGTGATACATTCCTAGTGGAAAGAGGCAAATTTCTACGTAAG AAGGAAGAATCCAGCAAGAATATCCAACAGTCAAATCACTTGCCCAAATATGAACGGGTCAAAGAACTATGCCAGCAGGCCAGGTACCAG ACAGCCTGTGAACAACCGGGGCAGAAGTGGCAATGCATTGAGGATACATCTGGCAAGCTTCGAATTCACAAGTGTAAAGGACCCAGTGAC CTGCTCACAGTCCGGCAGAGCACGCGGAACCTCTACGCTCGCGGCTTCCATGACAAAGACAAAGAGTGCAGTTGTAGGGAGTCTGGTTAC CGTGCCAGCAGAAGCCAAAGAAAGAGTCAACGGCAATTCTTGAGAAACCAGGGGACTCCAAGCATGGCTTTGGGAAGAAGACAAGAATTT GAGATCTGGCGTGAGGAAATATGGAGAGGGAAACTGGTCTAAAATACTGTTGCATTATAAATTCAACAACCGGACAAGTGTCATGTTAAA AGACAGATGGAGGACCATGAAGAAACTAAAACTGATTTCCTCAGACAGCGAAGACTGATTGTGTTTGTAAAAGCTTGATGAAAGGACAGT TAAGTATTTTGATCACTGCATTTTGTTTGAAACTTGTGTCATTGATGTAATTTAAAACTTTTGTTTAAAGCATTACAGTATTTTTCTGTG ACCATCAATTAATGAGGGTTTGTGCTACCAGAGTTAAAGCATATGCTATCATTGTATTCTTTAAGAACCTTATTTTGATAAAATGTAAAT TTGTTGAACCCTGCCACATTTAGTATCCCCACCCCCAAATCCTGTTCCAATGAAAAAATTAAAACCTGATACGAAAAAAAAAAAATTCCA GTTAACCTATTTTGTGTCTGTAGGCTGACCTCAACCCTGTAACGTAACCCATTAAAATGAATTTCTTTTTTTTTAAGACAGAGTTTCTCT CTGTTGCCCAGGCTGGAGTGCAGTGGCGCAATTTCAGCTCACTGCAACCTCTGCCTCCCAGGTTCAAGTGATTCTCCTGCCTCAGCCTCC TGAGTAGCTGGGATTACAGGCACACACCACCACGCCCAGCTAATTTTTGTATTTTTAGTAGAGGCGGGGTTTCACCATGCTGGTCAGGAT GTTCTCCAACTCCTGACTTCATGATCCACCCACCTCGGCCTCCCAAAGTGCTGAGATTACAGACGTGAGCCACTGCGTCCTGCCTAAAAT GAATTTTCTAGATGATTGAATAACAGTAGTCCTTTGATAGAAGATAATGACTTGGTTTATGGCCTTAATATACTACTTAATTACTTAAGA TGTTTATTAATAGAATGATAAATGTACAGAGTAACCTATAAGCATGACATACTTTTGCTTTCAGTAGTTTCATGTAAAGAAAAAAACTTG AAAATAGTAATACCTGAGTACCCATGGGAATAATAGACACTGGGGAGGTAGGGTGGGGAGCGGGAGCAAGAGCTGAAAAACTTACCTACT GGGGACTGTGCTCACTACCTGGGTGACAGGATCATACGTACCCCAAACCTCAACATCACACAGTATACTCAGCTAACAAACCTGCCCATG TGTTTCCTGAATCTAAAATAAAAATCGAAATAATTTTTTTAAAAAAGAAAAAGACAATAGTATTACCCATGGGACAAAATTTGTACTATT AGCAAGAATCATTTTGTGTCTCATTTAGAAACAATTTGACTTTTGTTCCAGTGTTTAAACTTTGACAAAAATGGTTTTGAATAGATCTTT ATAACCTGATGCCATAAATACAAGATTCTCTGATACCTTCATTTAATATATCAATATTGGGCCTAAAACAGTATTCTGTAAAGCTTAAAT TGGTATTAACTATGATCATCTTGATGTCTATGATAGATAATAAACAAGGTCATACATACCTTACTAAACAATTTTGGTTTTTCACCAACA TTTTATTCTTTAAAAGATTTAGACTAACAGAATTATTTAGCATTTCGAGTCATGTGCTTTATTTAGCAAGTGAGTAAAAATATTGGAATA TTGAAGTATTTGCATAAAAAATCAAATGGTGGTGTTTTGTAATCTCTATTGTATTTCCTATTAAGGTTTCATATATTACTTTCCCATTGT TCCTGAATTTGTTATCCTATATATAAACAGAAACATGGATGAGTACCATATACTTCCTGACTCCTTTATCTTGTTACACCACAAGATACT GCACTATTTATTGGAGATATTTTGATGATTAGTGCCAAGGCTGGCATCATGAGCCAAAATAGACTTGTTAAGTCAACCTCATTCCAAACA CCTGCTATAGATCATCAAATCTAAGTTGCCATTAATTGTAAGATGTCCTGTTATTTCACACACACAACTAGAAAAGAAAAATCGGTATCA ATTATAGTATGGTGCTTTCTTATTTTGAATTTTACTTATTAGAAGAGCTATTTTAGATGTATTTAAACATAAGATTTTTATCACATAACT >88037_88037_1_SULF1-TERF1_SULF1_chr8_70533486_ENST00000260128_TERF1_chr8_73958195_ENST00000276602_length(amino acids)=554AA_BP=532 MKYSCCALVLAVLGTELLGSLCSTVRSPRFRGRIQQERKNIRPNIILVLTDDQDVELGSLQVMNKTRKIMEHGGATFINAFVTTPMCCPS RSSMLTGKYVHNHNVYTNNENCSSPSWQAMHEPRTFAVYLNNTGYRTAFFGKYLNEYNGSYIPPGWREWLGLIKNSRFYNYTVCRNGIKE KHGFDYAKDYFTDLITNESINYFKMSKRMYPHRPVMMVISHAAPHGPEDSAPQFSKLYPNASQHITPSYNYAPNMDKHWIMQYTGPMLPI HMEFTNILQRKRLQTLMSVDDSVERLYNMLVETGELENTYIIYTADHGYHIGQFGLVKGKSMPYDFDIRVPFFIRGPSVEPGSIVPQIVL NIDLAPTILDIAGLDTPPDVDGKSVLKLLDPEKPGNRFRTNKKAKIWRDTFLVERGKFLRKKEESSKNIQQSNHLPKYERVKELCQQARY QTACEQPGQKWQCIEDTSGKLRIHKCKGPSDLLTVRQSTRNLYARGFHDKDKECSCRESGYRASRSQRKSQRQFLRNQGTPSMALGRRQE -------------------------------------------------------------- >88037_88037_2_SULF1-TERF1_SULF1_chr8_70533486_ENST00000260128_TERF1_chr8_73958196_ENST00000276602_length(transcript)=4473nt_BP=2311nt AGGTTACTTGACTGGGAGTTCTCAGACCTCCAGTTTCAGCCCTGCCCTCAGCCTCCAATCCGTAAGAGACACCCAGCCCCAGCAATTGGA TTGGGCAGCCCGTCTTGACACACCACTGTGCTGAGTGCTTGAGGACGTGTTTCAACAGATGGTTGGGGTTAGTGTGTGTCATCACATTCG AGTGGGGATTAAGAGAAGGAAGGCTGCCTTGCTGGAGCTGTGTGGTCTTCTCCAAGTGAGAGTCGCAGGCAATAGAACTACTTTGCTTTT GGAGGAAAAGGAGGAATTCATTTTCAGCAGACACAAGAAAAGCAGTTTTTTTTTCAGGGATTCTTCACTTCTCTTGAACAAGGAACTCAC TCAGAGACTAACACAAAGGAAGTAATTTCTTACCTGGTCATTATTTAGTCTACAATAAGTTCATCCTTCTTCAGTGTGACCAGTAAATTC TTCCCATACTCTTGAAGAGAGCATAATTGGAATGGAGAGGTGCTGACGGCCACCCACCATCATCTAAAGAAGATAAACTTGGCAAATGAC ATGCAGGTTCTTCAAGGCAGAATAATTGCAGAAAATCTTCAAAGGACCCTATCTGCAGATGTTCTGAATACCTCTGAGAATAGAGATTGA TTATTCAACCAGGATACCTAATTCAAGAACTCCAGAAATCAGGAGACGGAGACATTTTGTCAGTTTTGCAACATTGGACCAAATACAATG AAGTATTCTTGCTGTGCTCTGGTTTTGGCTGTCCTGGGCACAGAATTGCTGGGAAGCCTCTGTTCGACTGTCAGATCCCCGAGGTTCAGA GGACGGATACAGCAGGAACGAAAAAACATCCGACCCAACATTATTCTTGTGCTTACCGATGATCAAGATGTGGAGCTGGGGTCCCTGCAA GTCATGAACAAAACGAGAAAGATTATGGAACATGGGGGGGCCACCTTCATCAATGCCTTTGTGACTACACCCATGTGCTGCCCGTCACGG TCCTCCATGCTCACCGGGAAGTATGTGCACAATCACAATGTCTACACCAACAACGAGAACTGCTCTTCCCCCTCGTGGCAGGCCATGCAT GAGCCTCGGACTTTTGCTGTATATCTTAACAACACTGGCTACAGAACAGCCTTTTTTGGAAAATACCTCAATGAATATAATGGCAGCTAC ATCCCCCCTGGGTGGCGAGAATGGCTTGGATTAATCAAGAATTCTCGCTTCTATAATTACACTGTTTGTCGCAATGGCATCAAAGAAAAG CATGGATTTGATTATGCAAAGGACTACTTCACAGACTTAATCACTAACGAGAGCATTAATTACTTCAAAATGTCTAAGAGAATGTATCCC CATAGGCCCGTTATGATGGTGATCAGCCACGCTGCGCCCCACGGCCCCGAGGACTCAGCCCCACAGTTTTCTAAACTGTACCCCAATGCT TCCCAACACATAACTCCTAGTTATAACTATGCACCAAATATGGATAAACACTGGATTATGCAGTACACAGGACCAATGCTGCCCATCCAC ATGGAATTTACAAACATTCTACAGCGCAAAAGGCTCCAGACTTTGATGTCAGTGGATGATTCTGTGGAGAGGCTGTATAACATGCTCGTG GAGACGGGGGAGCTGGAGAATACTTACATCATTTACACCGCCGACCATGGTTACCATATTGGGCAGTTTGGACTGGTCAAGGGGAAATCC ATGCCATATGACTTTGATATTCGTGTGCCTTTTTTTATTCGTGGTCCAAGTGTAGAACCAGGATCAATAGTCCCACAGATCGTTCTCAAC ATTGACTTGGCCCCCACGATCCTGGATATTGCTGGGCTCGACACACCTCCTGATGTGGACGGCAAGTCTGTCCTCAAACTTCTGGACCCA GAAAAGCCAGGTAACAGGTTTCGAACAAACAAGAAGGCCAAAATTTGGCGTGATACATTCCTAGTGGAAAGAGGCAAATTTCTACGTAAG AAGGAAGAATCCAGCAAGAATATCCAACAGTCAAATCACTTGCCCAAATATGAACGGGTCAAAGAACTATGCCAGCAGGCCAGGTACCAG ACAGCCTGTGAACAACCGGGGCAGAAGTGGCAATGCATTGAGGATACATCTGGCAAGCTTCGAATTCACAAGTGTAAAGGACCCAGTGAC CTGCTCACAGTCCGGCAGAGCACGCGGAACCTCTACGCTCGCGGCTTCCATGACAAAGACAAAGAGTGCAGTTGTAGGGAGTCTGGTTAC CGTGCCAGCAGAAGCCAAAGAAAGAGTCAACGGCAATTCTTGAGAAACCAGGGGACTCCAAGCATGGCTTTGGGAAGAAGACAAGAATTT GAGATCTGGCGTGAGGAAATATGGAGAGGGAAACTGGTCTAAAATACTGTTGCATTATAAATTCAACAACCGGACAAGTGTCATGTTAAA AGACAGATGGAGGACCATGAAGAAACTAAAACTGATTTCCTCAGACAGCGAAGACTGATTGTGTTTGTAAAAGCTTGATGAAAGGACAGT TAAGTATTTTGATCACTGCATTTTGTTTGAAACTTGTGTCATTGATGTAATTTAAAACTTTTGTTTAAAGCATTACAGTATTTTTCTGTG ACCATCAATTAATGAGGGTTTGTGCTACCAGAGTTAAAGCATATGCTATCATTGTATTCTTTAAGAACCTTATTTTGATAAAATGTAAAT TTGTTGAACCCTGCCACATTTAGTATCCCCACCCCCAAATCCTGTTCCAATGAAAAAATTAAAACCTGATACGAAAAAAAAAAAATTCCA GTTAACCTATTTTGTGTCTGTAGGCTGACCTCAACCCTGTAACGTAACCCATTAAAATGAATTTCTTTTTTTTTAAGACAGAGTTTCTCT CTGTTGCCCAGGCTGGAGTGCAGTGGCGCAATTTCAGCTCACTGCAACCTCTGCCTCCCAGGTTCAAGTGATTCTCCTGCCTCAGCCTCC TGAGTAGCTGGGATTACAGGCACACACCACCACGCCCAGCTAATTTTTGTATTTTTAGTAGAGGCGGGGTTTCACCATGCTGGTCAGGAT GTTCTCCAACTCCTGACTTCATGATCCACCCACCTCGGCCTCCCAAAGTGCTGAGATTACAGACGTGAGCCACTGCGTCCTGCCTAAAAT GAATTTTCTAGATGATTGAATAACAGTAGTCCTTTGATAGAAGATAATGACTTGGTTTATGGCCTTAATATACTACTTAATTACTTAAGA TGTTTATTAATAGAATGATAAATGTACAGAGTAACCTATAAGCATGACATACTTTTGCTTTCAGTAGTTTCATGTAAAGAAAAAAACTTG AAAATAGTAATACCTGAGTACCCATGGGAATAATAGACACTGGGGAGGTAGGGTGGGGAGCGGGAGCAAGAGCTGAAAAACTTACCTACT GGGGACTGTGCTCACTACCTGGGTGACAGGATCATACGTACCCCAAACCTCAACATCACACAGTATACTCAGCTAACAAACCTGCCCATG TGTTTCCTGAATCTAAAATAAAAATCGAAATAATTTTTTTAAAAAAGAAAAAGACAATAGTATTACCCATGGGACAAAATTTGTACTATT AGCAAGAATCATTTTGTGTCTCATTTAGAAACAATTTGACTTTTGTTCCAGTGTTTAAACTTTGACAAAAATGGTTTTGAATAGATCTTT ATAACCTGATGCCATAAATACAAGATTCTCTGATACCTTCATTTAATATATCAATATTGGGCCTAAAACAGTATTCTGTAAAGCTTAAAT TGGTATTAACTATGATCATCTTGATGTCTATGATAGATAATAAACAAGGTCATACATACCTTACTAAACAATTTTGGTTTTTCACCAACA TTTTATTCTTTAAAAGATTTAGACTAACAGAATTATTTAGCATTTCGAGTCATGTGCTTTATTTAGCAAGTGAGTAAAAATATTGGAATA TTGAAGTATTTGCATAAAAAATCAAATGGTGGTGTTTTGTAATCTCTATTGTATTTCCTATTAAGGTTTCATATATTACTTTCCCATTGT TCCTGAATTTGTTATCCTATATATAAACAGAAACATGGATGAGTACCATATACTTCCTGACTCCTTTATCTTGTTACACCACAAGATACT GCACTATTTATTGGAGATATTTTGATGATTAGTGCCAAGGCTGGCATCATGAGCCAAAATAGACTTGTTAAGTCAACCTCATTCCAAACA CCTGCTATAGATCATCAAATCTAAGTTGCCATTAATTGTAAGATGTCCTGTTATTTCACACACACAACTAGAAAAGAAAAATCGGTATCA ATTATAGTATGGTGCTTTCTTATTTTGAATTTTACTTATTAGAAGAGCTATTTTAGATGTATTTAAACATAAGATTTTTATCACATAACT >88037_88037_2_SULF1-TERF1_SULF1_chr8_70533486_ENST00000260128_TERF1_chr8_73958196_ENST00000276602_length(amino acids)=554AA_BP=532 MKYSCCALVLAVLGTELLGSLCSTVRSPRFRGRIQQERKNIRPNIILVLTDDQDVELGSLQVMNKTRKIMEHGGATFINAFVTTPMCCPS RSSMLTGKYVHNHNVYTNNENCSSPSWQAMHEPRTFAVYLNNTGYRTAFFGKYLNEYNGSYIPPGWREWLGLIKNSRFYNYTVCRNGIKE KHGFDYAKDYFTDLITNESINYFKMSKRMYPHRPVMMVISHAAPHGPEDSAPQFSKLYPNASQHITPSYNYAPNMDKHWIMQYTGPMLPI HMEFTNILQRKRLQTLMSVDDSVERLYNMLVETGELENTYIIYTADHGYHIGQFGLVKGKSMPYDFDIRVPFFIRGPSVEPGSIVPQIVL NIDLAPTILDIAGLDTPPDVDGKSVLKLLDPEKPGNRFRTNKKAKIWRDTFLVERGKFLRKKEESSKNIQQSNHLPKYERVKELCQQARY QTACEQPGQKWQCIEDTSGKLRIHKCKGPSDLLTVRQSTRNLYARGFHDKDKECSCRESGYRASRSQRKSQRQFLRNQGTPSMALGRRQE -------------------------------------------------------------- >88037_88037_3_SULF1-TERF1_SULF1_chr8_70533486_ENST00000402687_TERF1_chr8_73958195_ENST00000276602_length(transcript)=4511nt_BP=2349nt TTTGTCTGGCAGCGTTGGTTCTATGGGGGTGTGTGATGATAATAATACGCGGGCTTATATAACCGTCTTCATCTTGCGAGCACTTCGCAG ACCGTCGCTAATGAATCTTGGGGCCGGTGTCGGGCCGGGGCGGCTTGATCGGCAACTAGGAAACCCCAGGCGCAGAGGCCAGGAGCGAGG GCAGCGAGGATCAGAGGCCAGGCCTTCCCGGCTGCCGGCGCTCCTCGGAGGTCAGGGCAGATGAGGAACATGACTCTCCCCCTTCGGAGG AGGAAGGAAGTCCCGCTGCCACCTTATCTCTGCTCCTCTGCCTCCTCCCTGTTCCCAGAGCTTTTTCTCTAGAGAAGATTTTGAAGGCGG CTTTTGGATTCTTCACTTCTCTTGAACAAGGAACTCACTCAGAGACTAACACAAAGGAAGTAATTTCTTACCTGGTCATTATTTAGTCTA CAATAAGTTCATCCTTCTTCAGTGTGACCAGTAAATTCTTCCCATACTCTTGAAGAGAGCATAATTGGAATGGAGAGGTGCTGACGGCCA CCCACCATCATCTAAAGAAGATAAACTTGGCAAATGACATGCAGGTTCTTCAAGGCAGAATAATTGCAGAAAATCTTCAAAGGACCCTAT CTGCAGATGTTCTGAATACCTCTGAGAATAGAGATTGATTATTCAACCAGGATACCTAATTCAAGAACTCCAGAAATCAGGAGACGGAGA CATTTTGTCAGTTTTGCAACATTGGACCAAATACAATGAAGTATTCTTGCTGTGCTCTGGTTTTGGCTGTCCTGGGCACAGAATTGCTGG GAAGCCTCTGTTCGACTGTCAGATCCCCGAGGTTCAGAGGACGGATACAGCAGGAACGAAAAAACATCCGACCCAACATTATTCTTGTGC TTACCGATGATCAAGATGTGGAGCTGGGGTCCCTGCAAGTCATGAACAAAACGAGAAAGATTATGGAACATGGGGGGGCCACCTTCATCA ATGCCTTTGTGACTACACCCATGTGCTGCCCGTCACGGTCCTCCATGCTCACCGGGAAGTATGTGCACAATCACAATGTCTACACCAACA ACGAGAACTGCTCTTCCCCCTCGTGGCAGGCCATGCATGAGCCTCGGACTTTTGCTGTATATCTTAACAACACTGGCTACAGAACAGCCT TTTTTGGAAAATACCTCAATGAATATAATGGCAGCTACATCCCCCCTGGGTGGCGAGAATGGCTTGGATTAATCAAGAATTCTCGCTTCT ATAATTACACTGTTTGTCGCAATGGCATCAAAGAAAAGCATGGATTTGATTATGCAAAGGACTACTTCACAGACTTAATCACTAACGAGA GCATTAATTACTTCAAAATGTCTAAGAGAATGTATCCCCATAGGCCCGTTATGATGGTGATCAGCCACGCTGCGCCCCACGGCCCCGAGG ACTCAGCCCCACAGTTTTCTAAACTGTACCCCAATGCTTCCCAACACATAACTCCTAGTTATAACTATGCACCAAATATGGATAAACACT GGATTATGCAGTACACAGGACCAATGCTGCCCATCCACATGGAATTTACAAACATTCTACAGCGCAAAAGGCTCCAGACTTTGATGTCAG TGGATGATTCTGTGGAGAGGCTGTATAACATGCTCGTGGAGACGGGGGAGCTGGAGAATACTTACATCATTTACACCGCCGACCATGGTT ACCATATTGGGCAGTTTGGACTGGTCAAGGGGAAATCCATGCCATATGACTTTGATATTCGTGTGCCTTTTTTTATTCGTGGTCCAAGTG TAGAACCAGGATCAATAGTCCCACAGATCGTTCTCAACATTGACTTGGCCCCCACGATCCTGGATATTGCTGGGCTCGACACACCTCCTG ATGTGGACGGCAAGTCTGTCCTCAAACTTCTGGACCCAGAAAAGCCAGGTAACAGGTTTCGAACAAACAAGAAGGCCAAAATTTGGCGTG ATACATTCCTAGTGGAAAGAGGCAAATTTCTACGTAAGAAGGAAGAATCCAGCAAGAATATCCAACAGTCAAATCACTTGCCCAAATATG AACGGGTCAAAGAACTATGCCAGCAGGCCAGGTACCAGACAGCCTGTGAACAACCGGGGCAGAAGTGGCAATGCATTGAGGATACATCTG GCAAGCTTCGAATTCACAAGTGTAAAGGACCCAGTGACCTGCTCACAGTCCGGCAGAGCACGCGGAACCTCTACGCTCGCGGCTTCCATG ACAAAGACAAAGAGTGCAGTTGTAGGGAGTCTGGTTACCGTGCCAGCAGAAGCCAAAGAAAGAGTCAACGGCAATTCTTGAGAAACCAGG GGACTCCAAGCATGGCTTTGGGAAGAAGACAAGAATTTGAGATCTGGCGTGAGGAAATATGGAGAGGGAAACTGGTCTAAAATACTGTTG CATTATAAATTCAACAACCGGACAAGTGTCATGTTAAAAGACAGATGGAGGACCATGAAGAAACTAAAACTGATTTCCTCAGACAGCGAA GACTGATTGTGTTTGTAAAAGCTTGATGAAAGGACAGTTAAGTATTTTGATCACTGCATTTTGTTTGAAACTTGTGTCATTGATGTAATT TAAAACTTTTGTTTAAAGCATTACAGTATTTTTCTGTGACCATCAATTAATGAGGGTTTGTGCTACCAGAGTTAAAGCATATGCTATCAT TGTATTCTTTAAGAACCTTATTTTGATAAAATGTAAATTTGTTGAACCCTGCCACATTTAGTATCCCCACCCCCAAATCCTGTTCCAATG AAAAAATTAAAACCTGATACGAAAAAAAAAAAATTCCAGTTAACCTATTTTGTGTCTGTAGGCTGACCTCAACCCTGTAACGTAACCCAT TAAAATGAATTTCTTTTTTTTTAAGACAGAGTTTCTCTCTGTTGCCCAGGCTGGAGTGCAGTGGCGCAATTTCAGCTCACTGCAACCTCT GCCTCCCAGGTTCAAGTGATTCTCCTGCCTCAGCCTCCTGAGTAGCTGGGATTACAGGCACACACCACCACGCCCAGCTAATTTTTGTAT TTTTAGTAGAGGCGGGGTTTCACCATGCTGGTCAGGATGTTCTCCAACTCCTGACTTCATGATCCACCCACCTCGGCCTCCCAAAGTGCT GAGATTACAGACGTGAGCCACTGCGTCCTGCCTAAAATGAATTTTCTAGATGATTGAATAACAGTAGTCCTTTGATAGAAGATAATGACT TGGTTTATGGCCTTAATATACTACTTAATTACTTAAGATGTTTATTAATAGAATGATAAATGTACAGAGTAACCTATAAGCATGACATAC TTTTGCTTTCAGTAGTTTCATGTAAAGAAAAAAACTTGAAAATAGTAATACCTGAGTACCCATGGGAATAATAGACACTGGGGAGGTAGG GTGGGGAGCGGGAGCAAGAGCTGAAAAACTTACCTACTGGGGACTGTGCTCACTACCTGGGTGACAGGATCATACGTACCCCAAACCTCA ACATCACACAGTATACTCAGCTAACAAACCTGCCCATGTGTTTCCTGAATCTAAAATAAAAATCGAAATAATTTTTTTAAAAAAGAAAAA GACAATAGTATTACCCATGGGACAAAATTTGTACTATTAGCAAGAATCATTTTGTGTCTCATTTAGAAACAATTTGACTTTTGTTCCAGT GTTTAAACTTTGACAAAAATGGTTTTGAATAGATCTTTATAACCTGATGCCATAAATACAAGATTCTCTGATACCTTCATTTAATATATC AATATTGGGCCTAAAACAGTATTCTGTAAAGCTTAAATTGGTATTAACTATGATCATCTTGATGTCTATGATAGATAATAAACAAGGTCA TACATACCTTACTAAACAATTTTGGTTTTTCACCAACATTTTATTCTTTAAAAGATTTAGACTAACAGAATTATTTAGCATTTCGAGTCA TGTGCTTTATTTAGCAAGTGAGTAAAAATATTGGAATATTGAAGTATTTGCATAAAAAATCAAATGGTGGTGTTTTGTAATCTCTATTGT ATTTCCTATTAAGGTTTCATATATTACTTTCCCATTGTTCCTGAATTTGTTATCCTATATATAAACAGAAACATGGATGAGTACCATATA CTTCCTGACTCCTTTATCTTGTTACACCACAAGATACTGCACTATTTATTGGAGATATTTTGATGATTAGTGCCAAGGCTGGCATCATGA GCCAAAATAGACTTGTTAAGTCAACCTCATTCCAAACACCTGCTATAGATCATCAAATCTAAGTTGCCATTAATTGTAAGATGTCCTGTT ATTTCACACACACAACTAGAAAAGAAAAATCGGTATCAATTATAGTATGGTGCTTTCTTATTTTGAATTTTACTTATTAGAAGAGCTATT TTAGATGTATTTAAACATAAGATTTTTATCACATAACTTGTGGATACAAAAAAAGAGAAATTGTAAGCAAAATAAGTTGGGTAATATATT >88037_88037_3_SULF1-TERF1_SULF1_chr8_70533486_ENST00000402687_TERF1_chr8_73958195_ENST00000276602_length(amino acids)=554AA_BP=532 MKYSCCALVLAVLGTELLGSLCSTVRSPRFRGRIQQERKNIRPNIILVLTDDQDVELGSLQVMNKTRKIMEHGGATFINAFVTTPMCCPS RSSMLTGKYVHNHNVYTNNENCSSPSWQAMHEPRTFAVYLNNTGYRTAFFGKYLNEYNGSYIPPGWREWLGLIKNSRFYNYTVCRNGIKE KHGFDYAKDYFTDLITNESINYFKMSKRMYPHRPVMMVISHAAPHGPEDSAPQFSKLYPNASQHITPSYNYAPNMDKHWIMQYTGPMLPI HMEFTNILQRKRLQTLMSVDDSVERLYNMLVETGELENTYIIYTADHGYHIGQFGLVKGKSMPYDFDIRVPFFIRGPSVEPGSIVPQIVL NIDLAPTILDIAGLDTPPDVDGKSVLKLLDPEKPGNRFRTNKKAKIWRDTFLVERGKFLRKKEESSKNIQQSNHLPKYERVKELCQQARY QTACEQPGQKWQCIEDTSGKLRIHKCKGPSDLLTVRQSTRNLYARGFHDKDKECSCRESGYRASRSQRKSQRQFLRNQGTPSMALGRRQE -------------------------------------------------------------- >88037_88037_4_SULF1-TERF1_SULF1_chr8_70533486_ENST00000402687_TERF1_chr8_73958196_ENST00000276602_length(transcript)=4511nt_BP=2349nt TTTGTCTGGCAGCGTTGGTTCTATGGGGGTGTGTGATGATAATAATACGCGGGCTTATATAACCGTCTTCATCTTGCGAGCACTTCGCAG ACCGTCGCTAATGAATCTTGGGGCCGGTGTCGGGCCGGGGCGGCTTGATCGGCAACTAGGAAACCCCAGGCGCAGAGGCCAGGAGCGAGG GCAGCGAGGATCAGAGGCCAGGCCTTCCCGGCTGCCGGCGCTCCTCGGAGGTCAGGGCAGATGAGGAACATGACTCTCCCCCTTCGGAGG AGGAAGGAAGTCCCGCTGCCACCTTATCTCTGCTCCTCTGCCTCCTCCCTGTTCCCAGAGCTTTTTCTCTAGAGAAGATTTTGAAGGCGG CTTTTGGATTCTTCACTTCTCTTGAACAAGGAACTCACTCAGAGACTAACACAAAGGAAGTAATTTCTTACCTGGTCATTATTTAGTCTA CAATAAGTTCATCCTTCTTCAGTGTGACCAGTAAATTCTTCCCATACTCTTGAAGAGAGCATAATTGGAATGGAGAGGTGCTGACGGCCA CCCACCATCATCTAAAGAAGATAAACTTGGCAAATGACATGCAGGTTCTTCAAGGCAGAATAATTGCAGAAAATCTTCAAAGGACCCTAT CTGCAGATGTTCTGAATACCTCTGAGAATAGAGATTGATTATTCAACCAGGATACCTAATTCAAGAACTCCAGAAATCAGGAGACGGAGA CATTTTGTCAGTTTTGCAACATTGGACCAAATACAATGAAGTATTCTTGCTGTGCTCTGGTTTTGGCTGTCCTGGGCACAGAATTGCTGG GAAGCCTCTGTTCGACTGTCAGATCCCCGAGGTTCAGAGGACGGATACAGCAGGAACGAAAAAACATCCGACCCAACATTATTCTTGTGC TTACCGATGATCAAGATGTGGAGCTGGGGTCCCTGCAAGTCATGAACAAAACGAGAAAGATTATGGAACATGGGGGGGCCACCTTCATCA ATGCCTTTGTGACTACACCCATGTGCTGCCCGTCACGGTCCTCCATGCTCACCGGGAAGTATGTGCACAATCACAATGTCTACACCAACA ACGAGAACTGCTCTTCCCCCTCGTGGCAGGCCATGCATGAGCCTCGGACTTTTGCTGTATATCTTAACAACACTGGCTACAGAACAGCCT TTTTTGGAAAATACCTCAATGAATATAATGGCAGCTACATCCCCCCTGGGTGGCGAGAATGGCTTGGATTAATCAAGAATTCTCGCTTCT ATAATTACACTGTTTGTCGCAATGGCATCAAAGAAAAGCATGGATTTGATTATGCAAAGGACTACTTCACAGACTTAATCACTAACGAGA GCATTAATTACTTCAAAATGTCTAAGAGAATGTATCCCCATAGGCCCGTTATGATGGTGATCAGCCACGCTGCGCCCCACGGCCCCGAGG ACTCAGCCCCACAGTTTTCTAAACTGTACCCCAATGCTTCCCAACACATAACTCCTAGTTATAACTATGCACCAAATATGGATAAACACT GGATTATGCAGTACACAGGACCAATGCTGCCCATCCACATGGAATTTACAAACATTCTACAGCGCAAAAGGCTCCAGACTTTGATGTCAG TGGATGATTCTGTGGAGAGGCTGTATAACATGCTCGTGGAGACGGGGGAGCTGGAGAATACTTACATCATTTACACCGCCGACCATGGTT ACCATATTGGGCAGTTTGGACTGGTCAAGGGGAAATCCATGCCATATGACTTTGATATTCGTGTGCCTTTTTTTATTCGTGGTCCAAGTG TAGAACCAGGATCAATAGTCCCACAGATCGTTCTCAACATTGACTTGGCCCCCACGATCCTGGATATTGCTGGGCTCGACACACCTCCTG ATGTGGACGGCAAGTCTGTCCTCAAACTTCTGGACCCAGAAAAGCCAGGTAACAGGTTTCGAACAAACAAGAAGGCCAAAATTTGGCGTG ATACATTCCTAGTGGAAAGAGGCAAATTTCTACGTAAGAAGGAAGAATCCAGCAAGAATATCCAACAGTCAAATCACTTGCCCAAATATG AACGGGTCAAAGAACTATGCCAGCAGGCCAGGTACCAGACAGCCTGTGAACAACCGGGGCAGAAGTGGCAATGCATTGAGGATACATCTG GCAAGCTTCGAATTCACAAGTGTAAAGGACCCAGTGACCTGCTCACAGTCCGGCAGAGCACGCGGAACCTCTACGCTCGCGGCTTCCATG ACAAAGACAAAGAGTGCAGTTGTAGGGAGTCTGGTTACCGTGCCAGCAGAAGCCAAAGAAAGAGTCAACGGCAATTCTTGAGAAACCAGG GGACTCCAAGCATGGCTTTGGGAAGAAGACAAGAATTTGAGATCTGGCGTGAGGAAATATGGAGAGGGAAACTGGTCTAAAATACTGTTG CATTATAAATTCAACAACCGGACAAGTGTCATGTTAAAAGACAGATGGAGGACCATGAAGAAACTAAAACTGATTTCCTCAGACAGCGAA GACTGATTGTGTTTGTAAAAGCTTGATGAAAGGACAGTTAAGTATTTTGATCACTGCATTTTGTTTGAAACTTGTGTCATTGATGTAATT TAAAACTTTTGTTTAAAGCATTACAGTATTTTTCTGTGACCATCAATTAATGAGGGTTTGTGCTACCAGAGTTAAAGCATATGCTATCAT TGTATTCTTTAAGAACCTTATTTTGATAAAATGTAAATTTGTTGAACCCTGCCACATTTAGTATCCCCACCCCCAAATCCTGTTCCAATG AAAAAATTAAAACCTGATACGAAAAAAAAAAAATTCCAGTTAACCTATTTTGTGTCTGTAGGCTGACCTCAACCCTGTAACGTAACCCAT TAAAATGAATTTCTTTTTTTTTAAGACAGAGTTTCTCTCTGTTGCCCAGGCTGGAGTGCAGTGGCGCAATTTCAGCTCACTGCAACCTCT GCCTCCCAGGTTCAAGTGATTCTCCTGCCTCAGCCTCCTGAGTAGCTGGGATTACAGGCACACACCACCACGCCCAGCTAATTTTTGTAT TTTTAGTAGAGGCGGGGTTTCACCATGCTGGTCAGGATGTTCTCCAACTCCTGACTTCATGATCCACCCACCTCGGCCTCCCAAAGTGCT GAGATTACAGACGTGAGCCACTGCGTCCTGCCTAAAATGAATTTTCTAGATGATTGAATAACAGTAGTCCTTTGATAGAAGATAATGACT TGGTTTATGGCCTTAATATACTACTTAATTACTTAAGATGTTTATTAATAGAATGATAAATGTACAGAGTAACCTATAAGCATGACATAC TTTTGCTTTCAGTAGTTTCATGTAAAGAAAAAAACTTGAAAATAGTAATACCTGAGTACCCATGGGAATAATAGACACTGGGGAGGTAGG GTGGGGAGCGGGAGCAAGAGCTGAAAAACTTACCTACTGGGGACTGTGCTCACTACCTGGGTGACAGGATCATACGTACCCCAAACCTCA ACATCACACAGTATACTCAGCTAACAAACCTGCCCATGTGTTTCCTGAATCTAAAATAAAAATCGAAATAATTTTTTTAAAAAAGAAAAA GACAATAGTATTACCCATGGGACAAAATTTGTACTATTAGCAAGAATCATTTTGTGTCTCATTTAGAAACAATTTGACTTTTGTTCCAGT GTTTAAACTTTGACAAAAATGGTTTTGAATAGATCTTTATAACCTGATGCCATAAATACAAGATTCTCTGATACCTTCATTTAATATATC AATATTGGGCCTAAAACAGTATTCTGTAAAGCTTAAATTGGTATTAACTATGATCATCTTGATGTCTATGATAGATAATAAACAAGGTCA TACATACCTTACTAAACAATTTTGGTTTTTCACCAACATTTTATTCTTTAAAAGATTTAGACTAACAGAATTATTTAGCATTTCGAGTCA TGTGCTTTATTTAGCAAGTGAGTAAAAATATTGGAATATTGAAGTATTTGCATAAAAAATCAAATGGTGGTGTTTTGTAATCTCTATTGT ATTTCCTATTAAGGTTTCATATATTACTTTCCCATTGTTCCTGAATTTGTTATCCTATATATAAACAGAAACATGGATGAGTACCATATA CTTCCTGACTCCTTTATCTTGTTACACCACAAGATACTGCACTATTTATTGGAGATATTTTGATGATTAGTGCCAAGGCTGGCATCATGA GCCAAAATAGACTTGTTAAGTCAACCTCATTCCAAACACCTGCTATAGATCATCAAATCTAAGTTGCCATTAATTGTAAGATGTCCTGTT ATTTCACACACACAACTAGAAAAGAAAAATCGGTATCAATTATAGTATGGTGCTTTCTTATTTTGAATTTTACTTATTAGAAGAGCTATT TTAGATGTATTTAAACATAAGATTTTTATCACATAACTTGTGGATACAAAAAAAGAGAAATTGTAAGCAAAATAAGTTGGGTAATATATT >88037_88037_4_SULF1-TERF1_SULF1_chr8_70533486_ENST00000402687_TERF1_chr8_73958196_ENST00000276602_length(amino acids)=554AA_BP=532 MKYSCCALVLAVLGTELLGSLCSTVRSPRFRGRIQQERKNIRPNIILVLTDDQDVELGSLQVMNKTRKIMEHGGATFINAFVTTPMCCPS RSSMLTGKYVHNHNVYTNNENCSSPSWQAMHEPRTFAVYLNNTGYRTAFFGKYLNEYNGSYIPPGWREWLGLIKNSRFYNYTVCRNGIKE KHGFDYAKDYFTDLITNESINYFKMSKRMYPHRPVMMVISHAAPHGPEDSAPQFSKLYPNASQHITPSYNYAPNMDKHWIMQYTGPMLPI HMEFTNILQRKRLQTLMSVDDSVERLYNMLVETGELENTYIIYTADHGYHIGQFGLVKGKSMPYDFDIRVPFFIRGPSVEPGSIVPQIVL NIDLAPTILDIAGLDTPPDVDGKSVLKLLDPEKPGNRFRTNKKAKIWRDTFLVERGKFLRKKEESSKNIQQSNHLPKYERVKELCQQARY QTACEQPGQKWQCIEDTSGKLRIHKCKGPSDLLTVRQSTRNLYARGFHDKDKECSCRESGYRASRSQRKSQRQFLRNQGTPSMALGRRQE -------------------------------------------------------------- >88037_88037_5_SULF1-TERF1_SULF1_chr8_70533486_ENST00000419716_TERF1_chr8_73958195_ENST00000276602_length(transcript)=4317nt_BP=2155nt GTGATGATAATAATACGCGGGCTTATATAACCGTCTTCATCTTGCGAGCACTTCGCAGACCGTCGCTAATGAATCTTGGGGCCGGTGTCG GGCCGGGGCGGCTTGATCGGCAACTAGGAAACCCCAGGCGCAGAGGCCAGGAGCGAGGGCAGCGAGGATCAGAGGCCAGGCCTTCCCGGC TGCCGGCGCTCCTCGGAGGTCAGGGCAGATGAGGAACATGACTCTCCCCCTTCGGAGGAGGAAGGAAGTCCCGCTGCCACCTTATCTCTG CTCCTCTGCCTCCTCCCTGTTCCCAGAGCTTTTTCTCTAGAGAAGATTTTGAAGGCGGCTTTTGTGCTGACGGCCACCCACCATCATCTA AAGAAGATAAACTTGGCAAATGACATGCAGGTTCTTCAAGGCAGAATAATTGCAGAAAATCTTCAAAGGACCCTATCTGCAGATGTTCTG AATACCTCTGAGAATAGAGATTGATTATTCAACCAGGATACCTAATTCAAGAACTCCAGAAATCAGGAGACGGAGACATTTTGTCAGTTT TGCAACATTGGACCAAATACAATGAAGTATTCTTGCTGTGCTCTGGTTTTGGCTGTCCTGGGCACAGAATTGCTGGGAAGCCTCTGTTCG ACTGTCAGATCCCCGAGGTTCAGAGGACGGATACAGCAGGAACGAAAAAACATCCGACCCAACATTATTCTTGTGCTTACCGATGATCAA GATGTGGAGCTGGGGTCCCTGCAAGTCATGAACAAAACGAGAAAGATTATGGAACATGGGGGGGCCACCTTCATCAATGCCTTTGTGACT ACACCCATGTGCTGCCCGTCACGGTCCTCCATGCTCACCGGGAAGTATGTGCACAATCACAATGTCTACACCAACAACGAGAACTGCTCT TCCCCCTCGTGGCAGGCCATGCATGAGCCTCGGACTTTTGCTGTATATCTTAACAACACTGGCTACAGAACAGCCTTTTTTGGAAAATAC CTCAATGAATATAATGGCAGCTACATCCCCCCTGGGTGGCGAGAATGGCTTGGATTAATCAAGAATTCTCGCTTCTATAATTACACTGTT TGTCGCAATGGCATCAAAGAAAAGCATGGATTTGATTATGCAAAGGACTACTTCACAGACTTAATCACTAACGAGAGCATTAATTACTTC AAAATGTCTAAGAGAATGTATCCCCATAGGCCCGTTATGATGGTGATCAGCCACGCTGCGCCCCACGGCCCCGAGGACTCAGCCCCACAG TTTTCTAAACTGTACCCCAATGCTTCCCAACACATAACTCCTAGTTATAACTATGCACCAAATATGGATAAACACTGGATTATGCAGTAC ACAGGACCAATGCTGCCCATCCACATGGAATTTACAAACATTCTACAGCGCAAAAGGCTCCAGACTTTGATGTCAGTGGATGATTCTGTG GAGAGGCTGTATAACATGCTCGTGGAGACGGGGGAGCTGGAGAATACTTACATCATTTACACCGCCGACCATGGTTACCATATTGGGCAG TTTGGACTGGTCAAGGGGAAATCCATGCCATATGACTTTGATATTCGTGTGCCTTTTTTTATTCGTGGTCCAAGTGTAGAACCAGGATCA ATAGTCCCACAGATCGTTCTCAACATTGACTTGGCCCCCACGATCCTGGATATTGCTGGGCTCGACACACCTCCTGATGTGGACGGCAAG TCTGTCCTCAAACTTCTGGACCCAGAAAAGCCAGGTAACAGGTTTCGAACAAACAAGAAGGCCAAAATTTGGCGTGATACATTCCTAGTG GAAAGAGGCAAATTTCTACGTAAGAAGGAAGAATCCAGCAAGAATATCCAACAGTCAAATCACTTGCCCAAATATGAACGGGTCAAAGAA CTATGCCAGCAGGCCAGGTACCAGACAGCCTGTGAACAACCGGGGCAGAAGTGGCAATGCATTGAGGATACATCTGGCAAGCTTCGAATT CACAAGTGTAAAGGACCCAGTGACCTGCTCACAGTCCGGCAGAGCACGCGGAACCTCTACGCTCGCGGCTTCCATGACAAAGACAAAGAG TGCAGTTGTAGGGAGTCTGGTTACCGTGCCAGCAGAAGCCAAAGAAAGAGTCAACGGCAATTCTTGAGAAACCAGGGGACTCCAAGCATG GCTTTGGGAAGAAGACAAGAATTTGAGATCTGGCGTGAGGAAATATGGAGAGGGAAACTGGTCTAAAATACTGTTGCATTATAAATTCAA CAACCGGACAAGTGTCATGTTAAAAGACAGATGGAGGACCATGAAGAAACTAAAACTGATTTCCTCAGACAGCGAAGACTGATTGTGTTT GTAAAAGCTTGATGAAAGGACAGTTAAGTATTTTGATCACTGCATTTTGTTTGAAACTTGTGTCATTGATGTAATTTAAAACTTTTGTTT AAAGCATTACAGTATTTTTCTGTGACCATCAATTAATGAGGGTTTGTGCTACCAGAGTTAAAGCATATGCTATCATTGTATTCTTTAAGA ACCTTATTTTGATAAAATGTAAATTTGTTGAACCCTGCCACATTTAGTATCCCCACCCCCAAATCCTGTTCCAATGAAAAAATTAAAACC TGATACGAAAAAAAAAAAATTCCAGTTAACCTATTTTGTGTCTGTAGGCTGACCTCAACCCTGTAACGTAACCCATTAAAATGAATTTCT TTTTTTTTAAGACAGAGTTTCTCTCTGTTGCCCAGGCTGGAGTGCAGTGGCGCAATTTCAGCTCACTGCAACCTCTGCCTCCCAGGTTCA AGTGATTCTCCTGCCTCAGCCTCCTGAGTAGCTGGGATTACAGGCACACACCACCACGCCCAGCTAATTTTTGTATTTTTAGTAGAGGCG GGGTTTCACCATGCTGGTCAGGATGTTCTCCAACTCCTGACTTCATGATCCACCCACCTCGGCCTCCCAAAGTGCTGAGATTACAGACGT GAGCCACTGCGTCCTGCCTAAAATGAATTTTCTAGATGATTGAATAACAGTAGTCCTTTGATAGAAGATAATGACTTGGTTTATGGCCTT AATATACTACTTAATTACTTAAGATGTTTATTAATAGAATGATAAATGTACAGAGTAACCTATAAGCATGACATACTTTTGCTTTCAGTA GTTTCATGTAAAGAAAAAAACTTGAAAATAGTAATACCTGAGTACCCATGGGAATAATAGACACTGGGGAGGTAGGGTGGGGAGCGGGAG CAAGAGCTGAAAAACTTACCTACTGGGGACTGTGCTCACTACCTGGGTGACAGGATCATACGTACCCCAAACCTCAACATCACACAGTAT ACTCAGCTAACAAACCTGCCCATGTGTTTCCTGAATCTAAAATAAAAATCGAAATAATTTTTTTAAAAAAGAAAAAGACAATAGTATTAC CCATGGGACAAAATTTGTACTATTAGCAAGAATCATTTTGTGTCTCATTTAGAAACAATTTGACTTTTGTTCCAGTGTTTAAACTTTGAC AAAAATGGTTTTGAATAGATCTTTATAACCTGATGCCATAAATACAAGATTCTCTGATACCTTCATTTAATATATCAATATTGGGCCTAA AACAGTATTCTGTAAAGCTTAAATTGGTATTAACTATGATCATCTTGATGTCTATGATAGATAATAAACAAGGTCATACATACCTTACTA AACAATTTTGGTTTTTCACCAACATTTTATTCTTTAAAAGATTTAGACTAACAGAATTATTTAGCATTTCGAGTCATGTGCTTTATTTAG CAAGTGAGTAAAAATATTGGAATATTGAAGTATTTGCATAAAAAATCAAATGGTGGTGTTTTGTAATCTCTATTGTATTTCCTATTAAGG TTTCATATATTACTTTCCCATTGTTCCTGAATTTGTTATCCTATATATAAACAGAAACATGGATGAGTACCATATACTTCCTGACTCCTT TATCTTGTTACACCACAAGATACTGCACTATTTATTGGAGATATTTTGATGATTAGTGCCAAGGCTGGCATCATGAGCCAAAATAGACTT GTTAAGTCAACCTCATTCCAAACACCTGCTATAGATCATCAAATCTAAGTTGCCATTAATTGTAAGATGTCCTGTTATTTCACACACACA ACTAGAAAAGAAAAATCGGTATCAATTATAGTATGGTGCTTTCTTATTTTGAATTTTACTTATTAGAAGAGCTATTTTAGATGTATTTAA >88037_88037_5_SULF1-TERF1_SULF1_chr8_70533486_ENST00000419716_TERF1_chr8_73958195_ENST00000276602_length(amino acids)=554AA_BP=532 MKYSCCALVLAVLGTELLGSLCSTVRSPRFRGRIQQERKNIRPNIILVLTDDQDVELGSLQVMNKTRKIMEHGGATFINAFVTTPMCCPS RSSMLTGKYVHNHNVYTNNENCSSPSWQAMHEPRTFAVYLNNTGYRTAFFGKYLNEYNGSYIPPGWREWLGLIKNSRFYNYTVCRNGIKE KHGFDYAKDYFTDLITNESINYFKMSKRMYPHRPVMMVISHAAPHGPEDSAPQFSKLYPNASQHITPSYNYAPNMDKHWIMQYTGPMLPI HMEFTNILQRKRLQTLMSVDDSVERLYNMLVETGELENTYIIYTADHGYHIGQFGLVKGKSMPYDFDIRVPFFIRGPSVEPGSIVPQIVL NIDLAPTILDIAGLDTPPDVDGKSVLKLLDPEKPGNRFRTNKKAKIWRDTFLVERGKFLRKKEESSKNIQQSNHLPKYERVKELCQQARY QTACEQPGQKWQCIEDTSGKLRIHKCKGPSDLLTVRQSTRNLYARGFHDKDKECSCRESGYRASRSQRKSQRQFLRNQGTPSMALGRRQE -------------------------------------------------------------- >88037_88037_6_SULF1-TERF1_SULF1_chr8_70533486_ENST00000419716_TERF1_chr8_73958196_ENST00000276602_length(transcript)=4317nt_BP=2155nt GTGATGATAATAATACGCGGGCTTATATAACCGTCTTCATCTTGCGAGCACTTCGCAGACCGTCGCTAATGAATCTTGGGGCCGGTGTCG GGCCGGGGCGGCTTGATCGGCAACTAGGAAACCCCAGGCGCAGAGGCCAGGAGCGAGGGCAGCGAGGATCAGAGGCCAGGCCTTCCCGGC TGCCGGCGCTCCTCGGAGGTCAGGGCAGATGAGGAACATGACTCTCCCCCTTCGGAGGAGGAAGGAAGTCCCGCTGCCACCTTATCTCTG CTCCTCTGCCTCCTCCCTGTTCCCAGAGCTTTTTCTCTAGAGAAGATTTTGAAGGCGGCTTTTGTGCTGACGGCCACCCACCATCATCTA AAGAAGATAAACTTGGCAAATGACATGCAGGTTCTTCAAGGCAGAATAATTGCAGAAAATCTTCAAAGGACCCTATCTGCAGATGTTCTG AATACCTCTGAGAATAGAGATTGATTATTCAACCAGGATACCTAATTCAAGAACTCCAGAAATCAGGAGACGGAGACATTTTGTCAGTTT TGCAACATTGGACCAAATACAATGAAGTATTCTTGCTGTGCTCTGGTTTTGGCTGTCCTGGGCACAGAATTGCTGGGAAGCCTCTGTTCG ACTGTCAGATCCCCGAGGTTCAGAGGACGGATACAGCAGGAACGAAAAAACATCCGACCCAACATTATTCTTGTGCTTACCGATGATCAA GATGTGGAGCTGGGGTCCCTGCAAGTCATGAACAAAACGAGAAAGATTATGGAACATGGGGGGGCCACCTTCATCAATGCCTTTGTGACT ACACCCATGTGCTGCCCGTCACGGTCCTCCATGCTCACCGGGAAGTATGTGCACAATCACAATGTCTACACCAACAACGAGAACTGCTCT TCCCCCTCGTGGCAGGCCATGCATGAGCCTCGGACTTTTGCTGTATATCTTAACAACACTGGCTACAGAACAGCCTTTTTTGGAAAATAC CTCAATGAATATAATGGCAGCTACATCCCCCCTGGGTGGCGAGAATGGCTTGGATTAATCAAGAATTCTCGCTTCTATAATTACACTGTT TGTCGCAATGGCATCAAAGAAAAGCATGGATTTGATTATGCAAAGGACTACTTCACAGACTTAATCACTAACGAGAGCATTAATTACTTC AAAATGTCTAAGAGAATGTATCCCCATAGGCCCGTTATGATGGTGATCAGCCACGCTGCGCCCCACGGCCCCGAGGACTCAGCCCCACAG TTTTCTAAACTGTACCCCAATGCTTCCCAACACATAACTCCTAGTTATAACTATGCACCAAATATGGATAAACACTGGATTATGCAGTAC ACAGGACCAATGCTGCCCATCCACATGGAATTTACAAACATTCTACAGCGCAAAAGGCTCCAGACTTTGATGTCAGTGGATGATTCTGTG GAGAGGCTGTATAACATGCTCGTGGAGACGGGGGAGCTGGAGAATACTTACATCATTTACACCGCCGACCATGGTTACCATATTGGGCAG TTTGGACTGGTCAAGGGGAAATCCATGCCATATGACTTTGATATTCGTGTGCCTTTTTTTATTCGTGGTCCAAGTGTAGAACCAGGATCA ATAGTCCCACAGATCGTTCTCAACATTGACTTGGCCCCCACGATCCTGGATATTGCTGGGCTCGACACACCTCCTGATGTGGACGGCAAG TCTGTCCTCAAACTTCTGGACCCAGAAAAGCCAGGTAACAGGTTTCGAACAAACAAGAAGGCCAAAATTTGGCGTGATACATTCCTAGTG GAAAGAGGCAAATTTCTACGTAAGAAGGAAGAATCCAGCAAGAATATCCAACAGTCAAATCACTTGCCCAAATATGAACGGGTCAAAGAA CTATGCCAGCAGGCCAGGTACCAGACAGCCTGTGAACAACCGGGGCAGAAGTGGCAATGCATTGAGGATACATCTGGCAAGCTTCGAATT CACAAGTGTAAAGGACCCAGTGACCTGCTCACAGTCCGGCAGAGCACGCGGAACCTCTACGCTCGCGGCTTCCATGACAAAGACAAAGAG TGCAGTTGTAGGGAGTCTGGTTACCGTGCCAGCAGAAGCCAAAGAAAGAGTCAACGGCAATTCTTGAGAAACCAGGGGACTCCAAGCATG GCTTTGGGAAGAAGACAAGAATTTGAGATCTGGCGTGAGGAAATATGGAGAGGGAAACTGGTCTAAAATACTGTTGCATTATAAATTCAA CAACCGGACAAGTGTCATGTTAAAAGACAGATGGAGGACCATGAAGAAACTAAAACTGATTTCCTCAGACAGCGAAGACTGATTGTGTTT GTAAAAGCTTGATGAAAGGACAGTTAAGTATTTTGATCACTGCATTTTGTTTGAAACTTGTGTCATTGATGTAATTTAAAACTTTTGTTT AAAGCATTACAGTATTTTTCTGTGACCATCAATTAATGAGGGTTTGTGCTACCAGAGTTAAAGCATATGCTATCATTGTATTCTTTAAGA ACCTTATTTTGATAAAATGTAAATTTGTTGAACCCTGCCACATTTAGTATCCCCACCCCCAAATCCTGTTCCAATGAAAAAATTAAAACC TGATACGAAAAAAAAAAAATTCCAGTTAACCTATTTTGTGTCTGTAGGCTGACCTCAACCCTGTAACGTAACCCATTAAAATGAATTTCT TTTTTTTTAAGACAGAGTTTCTCTCTGTTGCCCAGGCTGGAGTGCAGTGGCGCAATTTCAGCTCACTGCAACCTCTGCCTCCCAGGTTCA AGTGATTCTCCTGCCTCAGCCTCCTGAGTAGCTGGGATTACAGGCACACACCACCACGCCCAGCTAATTTTTGTATTTTTAGTAGAGGCG GGGTTTCACCATGCTGGTCAGGATGTTCTCCAACTCCTGACTTCATGATCCACCCACCTCGGCCTCCCAAAGTGCTGAGATTACAGACGT GAGCCACTGCGTCCTGCCTAAAATGAATTTTCTAGATGATTGAATAACAGTAGTCCTTTGATAGAAGATAATGACTTGGTTTATGGCCTT AATATACTACTTAATTACTTAAGATGTTTATTAATAGAATGATAAATGTACAGAGTAACCTATAAGCATGACATACTTTTGCTTTCAGTA GTTTCATGTAAAGAAAAAAACTTGAAAATAGTAATACCTGAGTACCCATGGGAATAATAGACACTGGGGAGGTAGGGTGGGGAGCGGGAG CAAGAGCTGAAAAACTTACCTACTGGGGACTGTGCTCACTACCTGGGTGACAGGATCATACGTACCCCAAACCTCAACATCACACAGTAT ACTCAGCTAACAAACCTGCCCATGTGTTTCCTGAATCTAAAATAAAAATCGAAATAATTTTTTTAAAAAAGAAAAAGACAATAGTATTAC CCATGGGACAAAATTTGTACTATTAGCAAGAATCATTTTGTGTCTCATTTAGAAACAATTTGACTTTTGTTCCAGTGTTTAAACTTTGAC AAAAATGGTTTTGAATAGATCTTTATAACCTGATGCCATAAATACAAGATTCTCTGATACCTTCATTTAATATATCAATATTGGGCCTAA AACAGTATTCTGTAAAGCTTAAATTGGTATTAACTATGATCATCTTGATGTCTATGATAGATAATAAACAAGGTCATACATACCTTACTA AACAATTTTGGTTTTTCACCAACATTTTATTCTTTAAAAGATTTAGACTAACAGAATTATTTAGCATTTCGAGTCATGTGCTTTATTTAG CAAGTGAGTAAAAATATTGGAATATTGAAGTATTTGCATAAAAAATCAAATGGTGGTGTTTTGTAATCTCTATTGTATTTCCTATTAAGG TTTCATATATTACTTTCCCATTGTTCCTGAATTTGTTATCCTATATATAAACAGAAACATGGATGAGTACCATATACTTCCTGACTCCTT TATCTTGTTACACCACAAGATACTGCACTATTTATTGGAGATATTTTGATGATTAGTGCCAAGGCTGGCATCATGAGCCAAAATAGACTT GTTAAGTCAACCTCATTCCAAACACCTGCTATAGATCATCAAATCTAAGTTGCCATTAATTGTAAGATGTCCTGTTATTTCACACACACA ACTAGAAAAGAAAAATCGGTATCAATTATAGTATGGTGCTTTCTTATTTTGAATTTTACTTATTAGAAGAGCTATTTTAGATGTATTTAA >88037_88037_6_SULF1-TERF1_SULF1_chr8_70533486_ENST00000419716_TERF1_chr8_73958196_ENST00000276602_length(amino acids)=554AA_BP=532 MKYSCCALVLAVLGTELLGSLCSTVRSPRFRGRIQQERKNIRPNIILVLTDDQDVELGSLQVMNKTRKIMEHGGATFINAFVTTPMCCPS RSSMLTGKYVHNHNVYTNNENCSSPSWQAMHEPRTFAVYLNNTGYRTAFFGKYLNEYNGSYIPPGWREWLGLIKNSRFYNYTVCRNGIKE KHGFDYAKDYFTDLITNESINYFKMSKRMYPHRPVMMVISHAAPHGPEDSAPQFSKLYPNASQHITPSYNYAPNMDKHWIMQYTGPMLPI HMEFTNILQRKRLQTLMSVDDSVERLYNMLVETGELENTYIIYTADHGYHIGQFGLVKGKSMPYDFDIRVPFFIRGPSVEPGSIVPQIVL NIDLAPTILDIAGLDTPPDVDGKSVLKLLDPEKPGNRFRTNKKAKIWRDTFLVERGKFLRKKEESSKNIQQSNHLPKYERVKELCQQARY QTACEQPGQKWQCIEDTSGKLRIHKCKGPSDLLTVRQSTRNLYARGFHDKDKECSCRESGYRASRSQRKSQRQFLRNQGTPSMALGRRQE -------------------------------------------------------------- >88037_88037_7_SULF1-TERF1_SULF1_chr8_70533486_ENST00000458141_TERF1_chr8_73958195_ENST00000276602_length(transcript)=4311nt_BP=2149nt AGGTTACTTGACTGGGAGTTCTCAGACCTCCAGTTTCAGCCCTGCCCTCAGCCTCCAATCCGTAAGAGACACCCAGCCCCAGCAATTGGA TTGGGCAGCCCGTCTTGACACACCACTGTGCTGAGTGCTTGAGGACGTGTTTCAACAGATGGTTGGGGTTAGTGTGTGTCATCACATTCG AGTGGGGATTAAGAGAAGGAAGGCTGCCTTGCTGGAGCTGTGTGGTCTTCTCCAAGTGAGAGTCGCAGGCAATAGAACTACTTTGCTTTT GGAGGAAAAGGAGGAATTCATTTTCAGCAGACACAAGAAAAGCAGTTTTTTTTTCAGGTGCTGACGGCCACCCACCATCATCTAAAGAAG ATAAACTTGGCAAATGACATGCAGGTTCTTCAAGGCAGAATAATTGCAGAAAATCTTCAAAGGACCCTATCTGCAGATGTTCTGAATACC TCTGAGAATAGAGATTGATTATTCAACCAGGATACCTAATTCAAGAACTCCAGAAATCAGGAGACGGAGACATTTTGTCAGTTTTGCAAC ATTGGACCAAATACAATGAAGTATTCTTGCTGTGCTCTGGTTTTGGCTGTCCTGGGCACAGAATTGCTGGGAAGCCTCTGTTCGACTGTC AGATCCCCGAGGTTCAGAGGACGGATACAGCAGGAACGAAAAAACATCCGACCCAACATTATTCTTGTGCTTACCGATGATCAAGATGTG GAGCTGGGGTCCCTGCAAGTCATGAACAAAACGAGAAAGATTATGGAACATGGGGGGGCCACCTTCATCAATGCCTTTGTGACTACACCC ATGTGCTGCCCGTCACGGTCCTCCATGCTCACCGGGAAGTATGTGCACAATCACAATGTCTACACCAACAACGAGAACTGCTCTTCCCCC TCGTGGCAGGCCATGCATGAGCCTCGGACTTTTGCTGTATATCTTAACAACACTGGCTACAGAACAGCCTTTTTTGGAAAATACCTCAAT GAATATAATGGCAGCTACATCCCCCCTGGGTGGCGAGAATGGCTTGGATTAATCAAGAATTCTCGCTTCTATAATTACACTGTTTGTCGC AATGGCATCAAAGAAAAGCATGGATTTGATTATGCAAAGGACTACTTCACAGACTTAATCACTAACGAGAGCATTAATTACTTCAAAATG TCTAAGAGAATGTATCCCCATAGGCCCGTTATGATGGTGATCAGCCACGCTGCGCCCCACGGCCCCGAGGACTCAGCCCCACAGTTTTCT AAACTGTACCCCAATGCTTCCCAACACATAACTCCTAGTTATAACTATGCACCAAATATGGATAAACACTGGATTATGCAGTACACAGGA CCAATGCTGCCCATCCACATGGAATTTACAAACATTCTACAGCGCAAAAGGCTCCAGACTTTGATGTCAGTGGATGATTCTGTGGAGAGG CTGTATAACATGCTCGTGGAGACGGGGGAGCTGGAGAATACTTACATCATTTACACCGCCGACCATGGTTACCATATTGGGCAGTTTGGA CTGGTCAAGGGGAAATCCATGCCATATGACTTTGATATTCGTGTGCCTTTTTTTATTCGTGGTCCAAGTGTAGAACCAGGATCAATAGTC CCACAGATCGTTCTCAACATTGACTTGGCCCCCACGATCCTGGATATTGCTGGGCTCGACACACCTCCTGATGTGGACGGCAAGTCTGTC CTCAAACTTCTGGACCCAGAAAAGCCAGGTAACAGGTTTCGAACAAACAAGAAGGCCAAAATTTGGCGTGATACATTCCTAGTGGAAAGA GGCAAATTTCTACGTAAGAAGGAAGAATCCAGCAAGAATATCCAACAGTCAAATCACTTGCCCAAATATGAACGGGTCAAAGAACTATGC CAGCAGGCCAGGTACCAGACAGCCTGTGAACAACCGGGGCAGAAGTGGCAATGCATTGAGGATACATCTGGCAAGCTTCGAATTCACAAG TGTAAAGGACCCAGTGACCTGCTCACAGTCCGGCAGAGCACGCGGAACCTCTACGCTCGCGGCTTCCATGACAAAGACAAAGAGTGCAGT TGTAGGGAGTCTGGTTACCGTGCCAGCAGAAGCCAAAGAAAGAGTCAACGGCAATTCTTGAGAAACCAGGGGACTCCAAGCATGGCTTTG GGAAGAAGACAAGAATTTGAGATCTGGCGTGAGGAAATATGGAGAGGGAAACTGGTCTAAAATACTGTTGCATTATAAATTCAACAACCG GACAAGTGTCATGTTAAAAGACAGATGGAGGACCATGAAGAAACTAAAACTGATTTCCTCAGACAGCGAAGACTGATTGTGTTTGTAAAA GCTTGATGAAAGGACAGTTAAGTATTTTGATCACTGCATTTTGTTTGAAACTTGTGTCATTGATGTAATTTAAAACTTTTGTTTAAAGCA TTACAGTATTTTTCTGTGACCATCAATTAATGAGGGTTTGTGCTACCAGAGTTAAAGCATATGCTATCATTGTATTCTTTAAGAACCTTA TTTTGATAAAATGTAAATTTGTTGAACCCTGCCACATTTAGTATCCCCACCCCCAAATCCTGTTCCAATGAAAAAATTAAAACCTGATAC GAAAAAAAAAAAATTCCAGTTAACCTATTTTGTGTCTGTAGGCTGACCTCAACCCTGTAACGTAACCCATTAAAATGAATTTCTTTTTTT TTAAGACAGAGTTTCTCTCTGTTGCCCAGGCTGGAGTGCAGTGGCGCAATTTCAGCTCACTGCAACCTCTGCCTCCCAGGTTCAAGTGAT TCTCCTGCCTCAGCCTCCTGAGTAGCTGGGATTACAGGCACACACCACCACGCCCAGCTAATTTTTGTATTTTTAGTAGAGGCGGGGTTT CACCATGCTGGTCAGGATGTTCTCCAACTCCTGACTTCATGATCCACCCACCTCGGCCTCCCAAAGTGCTGAGATTACAGACGTGAGCCA CTGCGTCCTGCCTAAAATGAATTTTCTAGATGATTGAATAACAGTAGTCCTTTGATAGAAGATAATGACTTGGTTTATGGCCTTAATATA CTACTTAATTACTTAAGATGTTTATTAATAGAATGATAAATGTACAGAGTAACCTATAAGCATGACATACTTTTGCTTTCAGTAGTTTCA TGTAAAGAAAAAAACTTGAAAATAGTAATACCTGAGTACCCATGGGAATAATAGACACTGGGGAGGTAGGGTGGGGAGCGGGAGCAAGAG CTGAAAAACTTACCTACTGGGGACTGTGCTCACTACCTGGGTGACAGGATCATACGTACCCCAAACCTCAACATCACACAGTATACTCAG CTAACAAACCTGCCCATGTGTTTCCTGAATCTAAAATAAAAATCGAAATAATTTTTTTAAAAAAGAAAAAGACAATAGTATTACCCATGG GACAAAATTTGTACTATTAGCAAGAATCATTTTGTGTCTCATTTAGAAACAATTTGACTTTTGTTCCAGTGTTTAAACTTTGACAAAAAT GGTTTTGAATAGATCTTTATAACCTGATGCCATAAATACAAGATTCTCTGATACCTTCATTTAATATATCAATATTGGGCCTAAAACAGT ATTCTGTAAAGCTTAAATTGGTATTAACTATGATCATCTTGATGTCTATGATAGATAATAAACAAGGTCATACATACCTTACTAAACAAT TTTGGTTTTTCACCAACATTTTATTCTTTAAAAGATTTAGACTAACAGAATTATTTAGCATTTCGAGTCATGTGCTTTATTTAGCAAGTG AGTAAAAATATTGGAATATTGAAGTATTTGCATAAAAAATCAAATGGTGGTGTTTTGTAATCTCTATTGTATTTCCTATTAAGGTTTCAT ATATTACTTTCCCATTGTTCCTGAATTTGTTATCCTATATATAAACAGAAACATGGATGAGTACCATATACTTCCTGACTCCTTTATCTT GTTACACCACAAGATACTGCACTATTTATTGGAGATATTTTGATGATTAGTGCCAAGGCTGGCATCATGAGCCAAAATAGACTTGTTAAG TCAACCTCATTCCAAACACCTGCTATAGATCATCAAATCTAAGTTGCCATTAATTGTAAGATGTCCTGTTATTTCACACACACAACTAGA AAAGAAAAATCGGTATCAATTATAGTATGGTGCTTTCTTATTTTGAATTTTACTTATTAGAAGAGCTATTTTAGATGTATTTAAACATAA >88037_88037_7_SULF1-TERF1_SULF1_chr8_70533486_ENST00000458141_TERF1_chr8_73958195_ENST00000276602_length(amino acids)=554AA_BP=532 MKYSCCALVLAVLGTELLGSLCSTVRSPRFRGRIQQERKNIRPNIILVLTDDQDVELGSLQVMNKTRKIMEHGGATFINAFVTTPMCCPS RSSMLTGKYVHNHNVYTNNENCSSPSWQAMHEPRTFAVYLNNTGYRTAFFGKYLNEYNGSYIPPGWREWLGLIKNSRFYNYTVCRNGIKE KHGFDYAKDYFTDLITNESINYFKMSKRMYPHRPVMMVISHAAPHGPEDSAPQFSKLYPNASQHITPSYNYAPNMDKHWIMQYTGPMLPI HMEFTNILQRKRLQTLMSVDDSVERLYNMLVETGELENTYIIYTADHGYHIGQFGLVKGKSMPYDFDIRVPFFIRGPSVEPGSIVPQIVL NIDLAPTILDIAGLDTPPDVDGKSVLKLLDPEKPGNRFRTNKKAKIWRDTFLVERGKFLRKKEESSKNIQQSNHLPKYERVKELCQQARY QTACEQPGQKWQCIEDTSGKLRIHKCKGPSDLLTVRQSTRNLYARGFHDKDKECSCRESGYRASRSQRKSQRQFLRNQGTPSMALGRRQE -------------------------------------------------------------- >88037_88037_8_SULF1-TERF1_SULF1_chr8_70533486_ENST00000458141_TERF1_chr8_73958196_ENST00000276602_length(transcript)=4311nt_BP=2149nt AGGTTACTTGACTGGGAGTTCTCAGACCTCCAGTTTCAGCCCTGCCCTCAGCCTCCAATCCGTAAGAGACACCCAGCCCCAGCAATTGGA TTGGGCAGCCCGTCTTGACACACCACTGTGCTGAGTGCTTGAGGACGTGTTTCAACAGATGGTTGGGGTTAGTGTGTGTCATCACATTCG AGTGGGGATTAAGAGAAGGAAGGCTGCCTTGCTGGAGCTGTGTGGTCTTCTCCAAGTGAGAGTCGCAGGCAATAGAACTACTTTGCTTTT GGAGGAAAAGGAGGAATTCATTTTCAGCAGACACAAGAAAAGCAGTTTTTTTTTCAGGTGCTGACGGCCACCCACCATCATCTAAAGAAG ATAAACTTGGCAAATGACATGCAGGTTCTTCAAGGCAGAATAATTGCAGAAAATCTTCAAAGGACCCTATCTGCAGATGTTCTGAATACC TCTGAGAATAGAGATTGATTATTCAACCAGGATACCTAATTCAAGAACTCCAGAAATCAGGAGACGGAGACATTTTGTCAGTTTTGCAAC ATTGGACCAAATACAATGAAGTATTCTTGCTGTGCTCTGGTTTTGGCTGTCCTGGGCACAGAATTGCTGGGAAGCCTCTGTTCGACTGTC AGATCCCCGAGGTTCAGAGGACGGATACAGCAGGAACGAAAAAACATCCGACCCAACATTATTCTTGTGCTTACCGATGATCAAGATGTG GAGCTGGGGTCCCTGCAAGTCATGAACAAAACGAGAAAGATTATGGAACATGGGGGGGCCACCTTCATCAATGCCTTTGTGACTACACCC ATGTGCTGCCCGTCACGGTCCTCCATGCTCACCGGGAAGTATGTGCACAATCACAATGTCTACACCAACAACGAGAACTGCTCTTCCCCC TCGTGGCAGGCCATGCATGAGCCTCGGACTTTTGCTGTATATCTTAACAACACTGGCTACAGAACAGCCTTTTTTGGAAAATACCTCAAT GAATATAATGGCAGCTACATCCCCCCTGGGTGGCGAGAATGGCTTGGATTAATCAAGAATTCTCGCTTCTATAATTACACTGTTTGTCGC AATGGCATCAAAGAAAAGCATGGATTTGATTATGCAAAGGACTACTTCACAGACTTAATCACTAACGAGAGCATTAATTACTTCAAAATG TCTAAGAGAATGTATCCCCATAGGCCCGTTATGATGGTGATCAGCCACGCTGCGCCCCACGGCCCCGAGGACTCAGCCCCACAGTTTTCT AAACTGTACCCCAATGCTTCCCAACACATAACTCCTAGTTATAACTATGCACCAAATATGGATAAACACTGGATTATGCAGTACACAGGA CCAATGCTGCCCATCCACATGGAATTTACAAACATTCTACAGCGCAAAAGGCTCCAGACTTTGATGTCAGTGGATGATTCTGTGGAGAGG CTGTATAACATGCTCGTGGAGACGGGGGAGCTGGAGAATACTTACATCATTTACACCGCCGACCATGGTTACCATATTGGGCAGTTTGGA CTGGTCAAGGGGAAATCCATGCCATATGACTTTGATATTCGTGTGCCTTTTTTTATTCGTGGTCCAAGTGTAGAACCAGGATCAATAGTC CCACAGATCGTTCTCAACATTGACTTGGCCCCCACGATCCTGGATATTGCTGGGCTCGACACACCTCCTGATGTGGACGGCAAGTCTGTC CTCAAACTTCTGGACCCAGAAAAGCCAGGTAACAGGTTTCGAACAAACAAGAAGGCCAAAATTTGGCGTGATACATTCCTAGTGGAAAGA GGCAAATTTCTACGTAAGAAGGAAGAATCCAGCAAGAATATCCAACAGTCAAATCACTTGCCCAAATATGAACGGGTCAAAGAACTATGC CAGCAGGCCAGGTACCAGACAGCCTGTGAACAACCGGGGCAGAAGTGGCAATGCATTGAGGATACATCTGGCAAGCTTCGAATTCACAAG TGTAAAGGACCCAGTGACCTGCTCACAGTCCGGCAGAGCACGCGGAACCTCTACGCTCGCGGCTTCCATGACAAAGACAAAGAGTGCAGT TGTAGGGAGTCTGGTTACCGTGCCAGCAGAAGCCAAAGAAAGAGTCAACGGCAATTCTTGAGAAACCAGGGGACTCCAAGCATGGCTTTG GGAAGAAGACAAGAATTTGAGATCTGGCGTGAGGAAATATGGAGAGGGAAACTGGTCTAAAATACTGTTGCATTATAAATTCAACAACCG GACAAGTGTCATGTTAAAAGACAGATGGAGGACCATGAAGAAACTAAAACTGATTTCCTCAGACAGCGAAGACTGATTGTGTTTGTAAAA GCTTGATGAAAGGACAGTTAAGTATTTTGATCACTGCATTTTGTTTGAAACTTGTGTCATTGATGTAATTTAAAACTTTTGTTTAAAGCA TTACAGTATTTTTCTGTGACCATCAATTAATGAGGGTTTGTGCTACCAGAGTTAAAGCATATGCTATCATTGTATTCTTTAAGAACCTTA TTTTGATAAAATGTAAATTTGTTGAACCCTGCCACATTTAGTATCCCCACCCCCAAATCCTGTTCCAATGAAAAAATTAAAACCTGATAC GAAAAAAAAAAAATTCCAGTTAACCTATTTTGTGTCTGTAGGCTGACCTCAACCCTGTAACGTAACCCATTAAAATGAATTTCTTTTTTT TTAAGACAGAGTTTCTCTCTGTTGCCCAGGCTGGAGTGCAGTGGCGCAATTTCAGCTCACTGCAACCTCTGCCTCCCAGGTTCAAGTGAT TCTCCTGCCTCAGCCTCCTGAGTAGCTGGGATTACAGGCACACACCACCACGCCCAGCTAATTTTTGTATTTTTAGTAGAGGCGGGGTTT CACCATGCTGGTCAGGATGTTCTCCAACTCCTGACTTCATGATCCACCCACCTCGGCCTCCCAAAGTGCTGAGATTACAGACGTGAGCCA CTGCGTCCTGCCTAAAATGAATTTTCTAGATGATTGAATAACAGTAGTCCTTTGATAGAAGATAATGACTTGGTTTATGGCCTTAATATA CTACTTAATTACTTAAGATGTTTATTAATAGAATGATAAATGTACAGAGTAACCTATAAGCATGACATACTTTTGCTTTCAGTAGTTTCA TGTAAAGAAAAAAACTTGAAAATAGTAATACCTGAGTACCCATGGGAATAATAGACACTGGGGAGGTAGGGTGGGGAGCGGGAGCAAGAG CTGAAAAACTTACCTACTGGGGACTGTGCTCACTACCTGGGTGACAGGATCATACGTACCCCAAACCTCAACATCACACAGTATACTCAG CTAACAAACCTGCCCATGTGTTTCCTGAATCTAAAATAAAAATCGAAATAATTTTTTTAAAAAAGAAAAAGACAATAGTATTACCCATGG GACAAAATTTGTACTATTAGCAAGAATCATTTTGTGTCTCATTTAGAAACAATTTGACTTTTGTTCCAGTGTTTAAACTTTGACAAAAAT GGTTTTGAATAGATCTTTATAACCTGATGCCATAAATACAAGATTCTCTGATACCTTCATTTAATATATCAATATTGGGCCTAAAACAGT ATTCTGTAAAGCTTAAATTGGTATTAACTATGATCATCTTGATGTCTATGATAGATAATAAACAAGGTCATACATACCTTACTAAACAAT TTTGGTTTTTCACCAACATTTTATTCTTTAAAAGATTTAGACTAACAGAATTATTTAGCATTTCGAGTCATGTGCTTTATTTAGCAAGTG AGTAAAAATATTGGAATATTGAAGTATTTGCATAAAAAATCAAATGGTGGTGTTTTGTAATCTCTATTGTATTTCCTATTAAGGTTTCAT ATATTACTTTCCCATTGTTCCTGAATTTGTTATCCTATATATAAACAGAAACATGGATGAGTACCATATACTTCCTGACTCCTTTATCTT GTTACACCACAAGATACTGCACTATTTATTGGAGATATTTTGATGATTAGTGCCAAGGCTGGCATCATGAGCCAAAATAGACTTGTTAAG TCAACCTCATTCCAAACACCTGCTATAGATCATCAAATCTAAGTTGCCATTAATTGTAAGATGTCCTGTTATTTCACACACACAACTAGA AAAGAAAAATCGGTATCAATTATAGTATGGTGCTTTCTTATTTTGAATTTTACTTATTAGAAGAGCTATTTTAGATGTATTTAAACATAA >88037_88037_8_SULF1-TERF1_SULF1_chr8_70533486_ENST00000458141_TERF1_chr8_73958196_ENST00000276602_length(amino acids)=554AA_BP=532 MKYSCCALVLAVLGTELLGSLCSTVRSPRFRGRIQQERKNIRPNIILVLTDDQDVELGSLQVMNKTRKIMEHGGATFINAFVTTPMCCPS RSSMLTGKYVHNHNVYTNNENCSSPSWQAMHEPRTFAVYLNNTGYRTAFFGKYLNEYNGSYIPPGWREWLGLIKNSRFYNYTVCRNGIKE KHGFDYAKDYFTDLITNESINYFKMSKRMYPHRPVMMVISHAAPHGPEDSAPQFSKLYPNASQHITPSYNYAPNMDKHWIMQYTGPMLPI HMEFTNILQRKRLQTLMSVDDSVERLYNMLVETGELENTYIIYTADHGYHIGQFGLVKGKSMPYDFDIRVPFFIRGPSVEPGSIVPQIVL NIDLAPTILDIAGLDTPPDVDGKSVLKLLDPEKPGNRFRTNKKAKIWRDTFLVERGKFLRKKEESSKNIQQSNHLPKYERVKELCQQARY QTACEQPGQKWQCIEDTSGKLRIHKCKGPSDLLTVRQSTRNLYARGFHDKDKECSCRESGYRASRSQRKSQRQFLRNQGTPSMALGRRQE -------------------------------------------------------------- |
Top |
Fusion Gene PPI Analysis for SULF1-TERF1 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| Tgene | TERF1 | chr8:70533486 | chr8:73958195 | ENST00000276602 | 7 | 9 | 265_378 | 361.0 | 420.0 | RLIM | |
| Tgene | TERF1 | chr8:70533486 | chr8:73958195 | ENST00000276603 | 8 | 10 | 265_378 | 381.0 | 440.0 | RLIM | |
| Tgene | TERF1 | chr8:70533486 | chr8:73958196 | ENST00000276602 | 7 | 9 | 265_378 | 361.0 | 420.0 | RLIM | |
| Tgene | TERF1 | chr8:70533486 | chr8:73958196 | ENST00000276603 | 8 | 10 | 265_378 | 381.0 | 440.0 | RLIM |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
Top |
Related Drugs for SULF1-TERF1 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.8 2021-05-08) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
Top |
Related Diseases for SULF1-TERF1 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
Copyright 2021-Present -The University of Texas Health Science Center at Houston (UTHealth)
Web File Viewing | Emergency Information |Campus Carry|Site Policies