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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:SULF1-TMED10 (FusionGDB2 ID:88038)

Fusion Gene Summary for SULF1-TMED10

check button Fusion gene summary
Fusion gene informationFusion gene name: SULF1-TMED10
Fusion gene ID: 88038
HgeneTgene
Gene symbol

SULF1

TMED10

Gene ID

23213

10972

Gene namesulfatase 1transmembrane p24 trafficking protein 10
SynonymsSULF-1P24(DELTA)|S31I125|S31III125|TMP21|Tmp-21-I|p23|p24d1
Cytomap

8q13.2-q13.3

14q24.3

Type of geneprotein-codingprotein-coding
Descriptionextracellular sulfatase Sulf-1sulfatase FPtransmembrane emp24 domain-containing protein 1021 kDa transmembrane trafficking proteinp24 family protein delta-1p24deltap24delta1testicular tissue protein Li 206transmembrane emp24-like trafficking protein 10transmembrane protein Tmp21
Modification date2020031320200313
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000521946, ENST00000260128, 
ENST00000402687, ENST00000419716, 
ENST00000458141, 		ENST00000303575, 
ENST00000557670, 
Fusion gene scores* DoF score13 X 15 X 5=9759 X 9 X 4=324
# samples 1611
** MAII scorelog2(16/975*10)=-2.60733031374961
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(11/324*10)=-1.55849028935997
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: SULF1 [Title/Abstract] AND TMED10 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointSULF1(70517137)-TMED10(75643112), # samples:5
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneSULF1

GO:0001937

negative regulation of endothelial cell proliferation

16778174

HgeneSULF1

GO:0016525

negative regulation of angiogenesis

16778174

HgeneSULF1

GO:0030177

positive regulation of Wnt signaling pathway

19520866

HgeneSULF1

GO:0030201

heparan sulfate proteoglycan metabolic process

18687675|19666466|19822709

HgeneSULF1

GO:0048010

vascular endothelial growth factor receptor signaling pathway

16778174

TgeneTMED10

GO:0006886

intracellular protein transport

20427317

TgeneTMED10

GO:0035964

COPI-coated vesicle budding

10052452


check buttonFusion gene breakpoints across SULF1 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across TMED10 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChiTaRS5.0N/AAX184520SULF1chr8

70517137

-TMED10chr14

75643112

-
ChiTaRS5.0N/AAX184521SULF1chr8

70517136

-TMED10chr14

75643109

-
ChiTaRS5.0N/AAX186183SULF1chr8

70517137

-TMED10chr14

75643112

-
ChiTaRS5.0N/AAX186184SULF1chr8

70517137

-TMED10chr14

75643112

-
ChiTaRS5.0N/AAX187386SULF1chr8

70517137

-TMED10chr14

75643112

-
ChiTaRS5.0N/AAX187387SULF1chr8

70517137

-TMED10chr14

75643112

-


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Fusion Gene ORF analysis for SULF1-TMED10

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
3UTR-3CDSENST00000521946ENST00000303575SULF1chr8

70517137

-TMED10chr14

75643112

-
3UTR-3CDSENST00000521946ENST00000303575SULF1chr8

70517136

-TMED10chr14

75643109

-
3UTR-intronENST00000521946ENST00000557670SULF1chr8

70517137

-TMED10chr14

75643112

-
3UTR-intronENST00000521946ENST00000557670SULF1chr8

70517136

-TMED10chr14

75643109

-
5CDS-intronENST00000260128ENST00000557670SULF1chr8

70517137

-TMED10chr14

75643112

-
5CDS-intronENST00000260128ENST00000557670SULF1chr8

70517136

-TMED10chr14

75643109

-
5CDS-intronENST00000402687ENST00000557670SULF1chr8

70517137

-TMED10chr14

75643112

-
5CDS-intronENST00000402687ENST00000557670SULF1chr8

70517136

-TMED10chr14

75643109

-
5CDS-intronENST00000419716ENST00000557670SULF1chr8

70517137

-TMED10chr14

75643112

-
5CDS-intronENST00000419716ENST00000557670SULF1chr8

70517136

-TMED10chr14

75643109

-
5CDS-intronENST00000458141ENST00000557670SULF1chr8

70517137

-TMED10chr14

75643112

-
5CDS-intronENST00000458141ENST00000557670SULF1chr8

70517136

-TMED10chr14

75643109

-
In-frameENST00000260128ENST00000303575SULF1chr8

70517137

-TMED10chr14

75643112

-
In-frameENST00000260128ENST00000303575SULF1chr8

70517136

-TMED10chr14

75643109

-
In-frameENST00000402687ENST00000303575SULF1chr8

70517137

-TMED10chr14

75643112

-
In-frameENST00000402687ENST00000303575SULF1chr8

70517136

-TMED10chr14

75643109

-
In-frameENST00000419716ENST00000303575SULF1chr8

70517137

-TMED10chr14

75643112

-
In-frameENST00000419716ENST00000303575SULF1chr8

70517136

-TMED10chr14

75643109

-
In-frameENST00000458141ENST00000303575SULF1chr8

70517137

-TMED10chr14

75643112

-
In-frameENST00000458141ENST00000303575SULF1chr8

70517136

-TMED10chr14

75643109

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000260128SULF1chr870517137-ENST00000303575TMED10chr1475643112-589919947172111464
ENST00000458141SULF1chr870517137-ENST00000303575TMED10chr1475643112-573718325551949464
ENST00000402687SULF1chr870517137-ENST00000303575TMED10chr1475643112-593720327552149464
ENST00000419716SULF1chr870517137-ENST00000303575TMED10chr1475643112-574318385611955464
ENST00000260128SULF1chr870517136-ENST00000303575TMED10chr1475643109-589719957172057446
ENST00000458141SULF1chr870517136-ENST00000303575TMED10chr1475643109-573518335551895446
ENST00000402687SULF1chr870517136-ENST00000303575TMED10chr1475643109-593520337552095446
ENST00000419716SULF1chr870517136-ENST00000303575TMED10chr1475643109-574118395611901446

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000260128ENST00000303575SULF1chr870517137-TMED10chr1475643112-0.0002009150.9997991
ENST00000458141ENST00000303575SULF1chr870517137-TMED10chr1475643112-0.0002037350.99979633
ENST00000402687ENST00000303575SULF1chr870517137-TMED10chr1475643112-0.000206880.9997931
ENST00000419716ENST00000303575SULF1chr870517137-TMED10chr1475643112-0.0002123940.9997876
ENST00000260128ENST00000303575SULF1chr870517136-TMED10chr1475643109-0.0001664570.99983346
ENST00000458141ENST00000303575SULF1chr870517136-TMED10chr1475643109-0.0001694630.9998305
ENST00000402687ENST00000303575SULF1chr870517136-TMED10chr1475643109-0.0001736220.9998264
ENST00000419716ENST00000303575SULF1chr870517136-TMED10chr1475643109-0.0001785890.9998215

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Fusion Genomic Features for SULF1-TMED10


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for SULF1-TMED10


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr8:70517137/chr14:75643112)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneTMED10chr8:70517136chr14:75643109ENST000003035750541_1930220.0DomainGOLD
TgeneTMED10chr8:70517137chr14:75643112ENST000003035750541_1930220.0DomainGOLD
TgeneTMED10chr8:70517136chr14:75643109ENST0000030357505211_2190220.0MotifNote=COPI vesicle coat-binding
TgeneTMED10chr8:70517137chr14:75643112ENST0000030357505211_2190220.0MotifNote=COPI vesicle coat-binding
TgeneTMED10chr8:70517136chr14:75643109ENST0000030357505147_1780220.0RegionNote=Required for TMED10 and TMED2 cis-Golgi network localization
TgeneTMED10chr8:70517137chr14:75643112ENST0000030357505147_1780220.0RegionNote=Required for TMED10 and TMED2 cis-Golgi network localization
TgeneTMED10chr8:70517136chr14:75643109ENST000003035750532_1850220.0Topological domainLumenal
TgeneTMED10chr8:70517137chr14:75643112ENST000003035750532_1850220.0Topological domainLumenal
TgeneTMED10chr8:70517136chr14:75643109ENST0000030357505186_2060220.0TransmembraneHelical
TgeneTMED10chr8:70517137chr14:75643112ENST0000030357505186_2060220.0TransmembraneHelical

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note


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Fusion Gene Sequence for SULF1-TMED10


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>88038_88038_1_SULF1-TMED10_SULF1_chr8_70517136_ENST00000260128_TMED10_chr14_75643109_ENST00000303575_length(transcript)=5897nt_BP=1995nt
AGGTTACTTGACTGGGAGTTCTCAGACCTCCAGTTTCAGCCCTGCCCTCAGCCTCCAATCCGTAAGAGACACCCAGCCCCAGCAATTGGA
TTGGGCAGCCCGTCTTGACACACCACTGTGCTGAGTGCTTGAGGACGTGTTTCAACAGATGGTTGGGGTTAGTGTGTGTCATCACATTCG
AGTGGGGATTAAGAGAAGGAAGGCTGCCTTGCTGGAGCTGTGTGGTCTTCTCCAAGTGAGAGTCGCAGGCAATAGAACTACTTTGCTTTT
GGAGGAAAAGGAGGAATTCATTTTCAGCAGACACAAGAAAAGCAGTTTTTTTTTCAGGGATTCTTCACTTCTCTTGAACAAGGAACTCAC
TCAGAGACTAACACAAAGGAAGTAATTTCTTACCTGGTCATTATTTAGTCTACAATAAGTTCATCCTTCTTCAGTGTGACCAGTAAATTC
TTCCCATACTCTTGAAGAGAGCATAATTGGAATGGAGAGGTGCTGACGGCCACCCACCATCATCTAAAGAAGATAAACTTGGCAAATGAC
ATGCAGGTTCTTCAAGGCAGAATAATTGCAGAAAATCTTCAAAGGACCCTATCTGCAGATGTTCTGAATACCTCTGAGAATAGAGATTGA
TTATTCAACCAGGATACCTAATTCAAGAACTCCAGAAATCAGGAGACGGAGACATTTTGTCAGTTTTGCAACATTGGACCAAATACAATG
AAGTATTCTTGCTGTGCTCTGGTTTTGGCTGTCCTGGGCACAGAATTGCTGGGAAGCCTCTGTTCGACTGTCAGATCCCCGAGGTTCAGA
GGACGGATACAGCAGGAACGAAAAAACATCCGACCCAACATTATTCTTGTGCTTACCGATGATCAAGATGTGGAGCTGGGGTCCCTGCAA
GTCATGAACAAAACGAGAAAGATTATGGAACATGGGGGGGCCACCTTCATCAATGCCTTTGTGACTACACCCATGTGCTGCCCGTCACGG
TCCTCCATGCTCACCGGGAAGTATGTGCACAATCACAATGTCTACACCAACAACGAGAACTGCTCTTCCCCCTCGTGGCAGGCCATGCAT
GAGCCTCGGACTTTTGCTGTATATCTTAACAACACTGGCTACAGAACAGCCTTTTTTGGAAAATACCTCAATGAATATAATGGCAGCTAC
ATCCCCCCTGGGTGGCGAGAATGGCTTGGATTAATCAAGAATTCTCGCTTCTATAATTACACTGTTTGTCGCAATGGCATCAAAGAAAAG
CATGGATTTGATTATGCAAAGGACTACTTCACAGACTTAATCACTAACGAGAGCATTAATTACTTCAAAATGTCTAAGAGAATGTATCCC
CATAGGCCCGTTATGATGGTGATCAGCCACGCTGCGCCCCACGGCCCCGAGGACTCAGCCCCACAGTTTTCTAAACTGTACCCCAATGCT
TCCCAACACATAACTCCTAGTTATAACTATGCACCAAATATGGATAAACACTGGATTATGCAGTACACAGGACCAATGCTGCCCATCCAC
ATGGAATTTACAAACATTCTACAGCGCAAAAGGCTCCAGACTTTGATGTCAGTGGATGATTCTGTGGAGAGGCTGTATAACATGCTCGTG
GAGACGGGGGAGCTGGAGAATACTTACATCATTTACACCGCCGACCATGGTTACCATATTGGGCAGTTTGGACTGGTCAAGGGGAAATCC
ATGCCATATGACTTTGATATTCGTGTGCCTTTTTTTATTCGTGGTCCAAGTGTAGAACCAGGATCAATAGTCCCACAGATCGTTCTCAAC
ATTGACTTGGCCCCCACGATCCTGGATATTGCTGGGCTCGACACACCTCCTGATGTGGACGGCAAGTCTGTCCTCAAACTTCTGGACCCA
GAAAAGCCAGGTAACAGGTTTCGAACAAACAAGAAGGCCAAAATTTGGCGTGATACATTCCTAGTGGAAAGAGGGTACCAGACAGCCTGT
GAACAACCGGGGCAGAGTCAACAAACACTCGGGTCCTATACTTCAGCATCTTTTCAATGTTCTGTCTCATTGGACTAGCTACCTGGCAGG
TCTTCTACCTGCGACGCTTCTTCAAGGCCAAGAAATTGATTGAGTAATGAATGAGGCATATTCTCCTCCCACCTTGTACCTCAGCCAGCA
GAACATCGCTGGGACGTGCCTGGCCTAAGGCATCCTACCAACAGCACCATCAAGGCACGTTGGAGCTTTCTTGCCAGAACTGATCTCTTT
TGGTGTGGGAGGACATGGGGTACCACCTACACCCAACAAGTCAATGAGGGACTTCTTTTTAATTTGGTAGGATTTTGACTGGTTTTGCAA
CAATAGGTCTATTATTAGAGTCACCTATGACAAAAAATAGGGGTTACCTAGATAATGCCAAAGTCAGCATTTGTCCTGGGTTCCCTTGTG
TGATCTGTTTGGACTATGTTTTCTTTTCTTCTCCCACTTGCTCAGCAGCTTGGGCTTCCATTCTAGTTCTTTTACCAAGATTTTTGTGTG
ACCATGTTGACTTCATTTGGATTGCCCTCTTTCAATTTCCTTGTGAAAACACCCTTAACTTTCTCTTTACCCTTAGCTGAAATGTTTACA
TAGCTTCTGGTGATATCTTTTCATGATTTTATATCTCTTAAAATGGTGATGGATGTGACACCTCATAAAAGTGAGCTTTGAACTGTAGAT
AACTCTTAAAGAAAATGTCATTTTAGACAATTAAAATATTTGTGCTCAACTGCTTGAACTTTTTTCGTGTATGTGTATTTAATTCTATGC
AATATTATCACATGTGTAGATTCATGTGACCACCATCACAAGAGACAGAACAGTTCTGTCACATGGATCCCTTGCACTGCCCTTTTACAG
CCGCAGCCACATCCCTTTCTTATACCCTCACCCCAACCTGTGGCTACCACTGTTCTGTCCTCCATCTCTGTAATTTTGTCATTTCAAGAA
TGTTGTATGAATGGAATCATACAGAATGTAATCTTACGAGGCTGATCTTTTTTCATTCAGCATAATTCCCTTGAAATCCATCCAAGTTGT
TGCATGTATGAATAGTTTCTTCCTTTTTTTCTTTTAAAAATGTTTTATATATTTAGGGGGTATAAGTACAGATTTCTTACATGCATATAT
TGCATCGTGGTGAAGTGGGGGCAGTTCCTTTTGATTGCTGAGTAGTATTCCATGGTATGGATGTACCACAGTTTGCTTAACCATTCACCC
ACTAAAGGACATAAGAGTTGTTTTCAGTTTTTTGCCCTAATAAAGCTGCTGTGAACATTCATGTACAGGTTTTTATGTGAACATACATTT
TCATTTTCTGGGATAAATGCTCAAAAGGGCAACTGTTGGGTTGTATGGTAAACACATATATTTTTGTAAGAAACTACCCTACTCTTTTTC
CAGAGTGGCTCTACTTTTTACATACAGCCACTCATACAATTCAGACAGCAATGTATGATTGATCCAGTTTCTTCACATCCTCACCAGCAT
TTGGTATTACTACTATTTTTTATCTTAACCATTCACATAGATGTGTGTAATGATACCACATGTGGTTTTAATTTGCATTTCCAATGGCTA
ATGATGTTGAGTATCTTTTTGTGTGCTAATTTGCCATCTATGTATCCTCTTCGGTGAAATGTCTTCATGTCTTTTGTCTATTTTCTATTT
AGGTCATTTGTTCTTTTTACTATTGAGTTTTGAGAGGTTTTTTATATATCCTAGATAAAATTCCTCTGTTAGATATGTGGTTGCTTGAAT
TTTTAACATAACTTCTACCAAGGAAAAATAAGTAAAATTTCCAACCCTTGCATGGCCAGTCACTTACTTAATTCCTGTCCTTCAGTGTTC
CATCTAGAGAATTAAGAGATATGATGTATAAAATAGACATCGAGGGCCATTAAGAGAGTAAATACTTAAAAATACATGTTATGAAAGCAA
AGCCAATAATCACTGTAGGAGTATGAGTTGCCTAAGGGCCAAAACTAATGTAAATAAGAGAAAGTGTGGATATAAATGACCATTGTTTAT
AAACAGTTATGAAAAATGCTGTGACTTGAAATCTTTCCCACATCTCCCAAGAAAGTAGGTAGGAGTTTATCCTTTCCGTAATCTCTTTTT
AACCCTGCTGACTATTACAGGGCTTGTTTAATCACAGTGGCAAGAATTACATGTATCTTACAGTAAAGAAACAGAATACTGGAATCGTTA
GAGAACCCTGATGTGTTGACCTGGATAAAGTACAAAGGTGGAAGAGGGAATGAGTTATGCTGTTAAAATCTCAGGCTATTCTGTTAATGT
TCCTGCTACTATGAACCCAAACTTTTTTTTTCCCCCTTTTGACTCCTTGTGTCTTCCTCTCCTGTGGCATAAAAGTAGTTCTGTCGTTAA
CTTGTACAACATTGCCATCTGCTGTTGAGAATTGGTAGGTACTGCTTCTGAGAACCTGGCTGCAGATCCTTAGCATAGGCAGCAAATGTT
GAGAAAGTCTATCTGTAGTATTACATATACTAAGTTACAGAGGATGCATCCAAGTAGAGAAAATAATATGTGGGTTAAGATACATCCTTA
AACTTTTTTTTTTTTGGGGGGGGGGGGACGGAGTCTTGCTGCAACGCCCAGGCTGGAGTGCAATGGCACTATCTCAGCTCGCTGCAACCT
TCACCTCCTGGGTTCAAGCAATTCTCCTGCCTCAGCCTCCTGAGTAGCTGGGAATATAGGTGCACACCACCATGCCTGGCTAATTTTTGT
ATTTTCAGTAGAAGCAGAGTTTCACCATATTGGCCAGGTTGGTCTCGAACTCCTGACCTCAAGTGATCTGCCTGCCTCAGCCTCCCAAAG
TGCTGGGATTACACGCGTGAGCCACCACACCCAGCCTCCATCTTTAAACTTTTAAATGTGAAATTTCTATCATGTACCGTTAGCCTAACA
AGATTTTCTTTCCTATTTCTGACTGGTGCCTTTCCCCTTTTTAGGAGCAACGAAAGCTACTCTCTTAGTTATGTTCTTGTGATGTGACAA
AATGTCAAGAAGATAGGAGAAGAGAATATTTTATTTCGTTGATGCTTTTGTTCCCAAGTGTGACCCTAAACTTAAGCTTTGTAGGAGTTG
ACATTCTTTCATGTCCCTTCCCTTTACTCATGCCGAAACTATCAACTGGGACATTTTGTGCTTTTGGTTTAAAAGTTAATTGATATTATA
CTTTGGTTTTATCTAAAAAGTAAATGTATTTGCCTTTGACAAAAGACTGACACAAGAGCAAATAAGCTTTAAAATCGGGTGTTATGTGCT
TTCCTCCATTTTTGAGCATATTATCCAAAATGGTCTGTATAATATAAATGAGAATGATGCAGTTTAAGTAAGCCTTGTTATACCATTGTC
ATGGACCCCTGTCATAAAGCCATTTCTTGGTTTGTTTGGGAAAGAGGCATATGGGATTTATACAGATTCACTTGTAAATGTTGGATTGGG
GATTTTTGTGTAAATTTTCTCAAATAAAGGCTAGCAGAAACCATTGCAAAAGTTGAGAAGCTCAAACCATTAGAGGTAGAGCTGCGACGC
CTAGAAGACCTTTCAGAATCTATTGTTAATGATTTTGCCTACATGAAGAAGAGAGAAGAGGAGATGCGTGATACCAACGGAACAGGGCGG
ATACCTGACCAACTCGTGATCCTAGACATGAAGCATGGAGTGGAGGCGAAAAATTACGAAGAGATCACAGATTCTGCTGGCCATATTCTC
TACTCCAAAGAGGATGCAACCAAGGGGAAATTTGCCTTTACCACTGAAGATTATGACATGTTTGAAGTGTGTTTTGAGAGCAAGGCGAGA

>88038_88038_1_SULF1-TMED10_SULF1_chr8_70517136_ENST00000260128_TMED10_chr14_75643109_ENST00000303575_length(amino acids)=446AA_BP=
MKYSCCALVLAVLGTELLGSLCSTVRSPRFRGRIQQERKNIRPNIILVLTDDQDVELGSLQVMNKTRKIMEHGGATFINAFVTTPMCCPS
RSSMLTGKYVHNHNVYTNNENCSSPSWQAMHEPRTFAVYLNNTGYRTAFFGKYLNEYNGSYIPPGWREWLGLIKNSRFYNYTVCRNGIKE
KHGFDYAKDYFTDLITNESINYFKMSKRMYPHRPVMMVISHAAPHGPEDSAPQFSKLYPNASQHITPSYNYAPNMDKHWIMQYTGPMLPI
HMEFTNILQRKRLQTLMSVDDSVERLYNMLVETGELENTYIIYTADHGYHIGQFGLVKGKSMPYDFDIRVPFFIRGPSVEPGSIVPQIVL

--------------------------------------------------------------
>88038_88038_2_SULF1-TMED10_SULF1_chr8_70517136_ENST00000402687_TMED10_chr14_75643109_ENST00000303575_length(transcript)=5935nt_BP=2033nt
TTTGTCTGGCAGCGTTGGTTCTATGGGGGTGTGTGATGATAATAATACGCGGGCTTATATAACCGTCTTCATCTTGCGAGCACTTCGCAG
ACCGTCGCTAATGAATCTTGGGGCCGGTGTCGGGCCGGGGCGGCTTGATCGGCAACTAGGAAACCCCAGGCGCAGAGGCCAGGAGCGAGG
GCAGCGAGGATCAGAGGCCAGGCCTTCCCGGCTGCCGGCGCTCCTCGGAGGTCAGGGCAGATGAGGAACATGACTCTCCCCCTTCGGAGG
AGGAAGGAAGTCCCGCTGCCACCTTATCTCTGCTCCTCTGCCTCCTCCCTGTTCCCAGAGCTTTTTCTCTAGAGAAGATTTTGAAGGCGG
CTTTTGGATTCTTCACTTCTCTTGAACAAGGAACTCACTCAGAGACTAACACAAAGGAAGTAATTTCTTACCTGGTCATTATTTAGTCTA
CAATAAGTTCATCCTTCTTCAGTGTGACCAGTAAATTCTTCCCATACTCTTGAAGAGAGCATAATTGGAATGGAGAGGTGCTGACGGCCA
CCCACCATCATCTAAAGAAGATAAACTTGGCAAATGACATGCAGGTTCTTCAAGGCAGAATAATTGCAGAAAATCTTCAAAGGACCCTAT
CTGCAGATGTTCTGAATACCTCTGAGAATAGAGATTGATTATTCAACCAGGATACCTAATTCAAGAACTCCAGAAATCAGGAGACGGAGA
CATTTTGTCAGTTTTGCAACATTGGACCAAATACAATGAAGTATTCTTGCTGTGCTCTGGTTTTGGCTGTCCTGGGCACAGAATTGCTGG
GAAGCCTCTGTTCGACTGTCAGATCCCCGAGGTTCAGAGGACGGATACAGCAGGAACGAAAAAACATCCGACCCAACATTATTCTTGTGC
TTACCGATGATCAAGATGTGGAGCTGGGGTCCCTGCAAGTCATGAACAAAACGAGAAAGATTATGGAACATGGGGGGGCCACCTTCATCA
ATGCCTTTGTGACTACACCCATGTGCTGCCCGTCACGGTCCTCCATGCTCACCGGGAAGTATGTGCACAATCACAATGTCTACACCAACA
ACGAGAACTGCTCTTCCCCCTCGTGGCAGGCCATGCATGAGCCTCGGACTTTTGCTGTATATCTTAACAACACTGGCTACAGAACAGCCT
TTTTTGGAAAATACCTCAATGAATATAATGGCAGCTACATCCCCCCTGGGTGGCGAGAATGGCTTGGATTAATCAAGAATTCTCGCTTCT
ATAATTACACTGTTTGTCGCAATGGCATCAAAGAAAAGCATGGATTTGATTATGCAAAGGACTACTTCACAGACTTAATCACTAACGAGA
GCATTAATTACTTCAAAATGTCTAAGAGAATGTATCCCCATAGGCCCGTTATGATGGTGATCAGCCACGCTGCGCCCCACGGCCCCGAGG
ACTCAGCCCCACAGTTTTCTAAACTGTACCCCAATGCTTCCCAACACATAACTCCTAGTTATAACTATGCACCAAATATGGATAAACACT
GGATTATGCAGTACACAGGACCAATGCTGCCCATCCACATGGAATTTACAAACATTCTACAGCGCAAAAGGCTCCAGACTTTGATGTCAG
TGGATGATTCTGTGGAGAGGCTGTATAACATGCTCGTGGAGACGGGGGAGCTGGAGAATACTTACATCATTTACACCGCCGACCATGGTT
ACCATATTGGGCAGTTTGGACTGGTCAAGGGGAAATCCATGCCATATGACTTTGATATTCGTGTGCCTTTTTTTATTCGTGGTCCAAGTG
TAGAACCAGGATCAATAGTCCCACAGATCGTTCTCAACATTGACTTGGCCCCCACGATCCTGGATATTGCTGGGCTCGACACACCTCCTG
ATGTGGACGGCAAGTCTGTCCTCAAACTTCTGGACCCAGAAAAGCCAGGTAACAGGTTTCGAACAAACAAGAAGGCCAAAATTTGGCGTG
ATACATTCCTAGTGGAAAGAGGGTACCAGACAGCCTGTGAACAACCGGGGCAGAGTCAACAAACACTCGGGTCCTATACTTCAGCATCTT
TTCAATGTTCTGTCTCATTGGACTAGCTACCTGGCAGGTCTTCTACCTGCGACGCTTCTTCAAGGCCAAGAAATTGATTGAGTAATGAAT
GAGGCATATTCTCCTCCCACCTTGTACCTCAGCCAGCAGAACATCGCTGGGACGTGCCTGGCCTAAGGCATCCTACCAACAGCACCATCA
AGGCACGTTGGAGCTTTCTTGCCAGAACTGATCTCTTTTGGTGTGGGAGGACATGGGGTACCACCTACACCCAACAAGTCAATGAGGGAC
TTCTTTTTAATTTGGTAGGATTTTGACTGGTTTTGCAACAATAGGTCTATTATTAGAGTCACCTATGACAAAAAATAGGGGTTACCTAGA
TAATGCCAAAGTCAGCATTTGTCCTGGGTTCCCTTGTGTGATCTGTTTGGACTATGTTTTCTTTTCTTCTCCCACTTGCTCAGCAGCTTG
GGCTTCCATTCTAGTTCTTTTACCAAGATTTTTGTGTGACCATGTTGACTTCATTTGGATTGCCCTCTTTCAATTTCCTTGTGAAAACAC
CCTTAACTTTCTCTTTACCCTTAGCTGAAATGTTTACATAGCTTCTGGTGATATCTTTTCATGATTTTATATCTCTTAAAATGGTGATGG
ATGTGACACCTCATAAAAGTGAGCTTTGAACTGTAGATAACTCTTAAAGAAAATGTCATTTTAGACAATTAAAATATTTGTGCTCAACTG
CTTGAACTTTTTTCGTGTATGTGTATTTAATTCTATGCAATATTATCACATGTGTAGATTCATGTGACCACCATCACAAGAGACAGAACA
GTTCTGTCACATGGATCCCTTGCACTGCCCTTTTACAGCCGCAGCCACATCCCTTTCTTATACCCTCACCCCAACCTGTGGCTACCACTG
TTCTGTCCTCCATCTCTGTAATTTTGTCATTTCAAGAATGTTGTATGAATGGAATCATACAGAATGTAATCTTACGAGGCTGATCTTTTT
TCATTCAGCATAATTCCCTTGAAATCCATCCAAGTTGTTGCATGTATGAATAGTTTCTTCCTTTTTTTCTTTTAAAAATGTTTTATATAT
TTAGGGGGTATAAGTACAGATTTCTTACATGCATATATTGCATCGTGGTGAAGTGGGGGCAGTTCCTTTTGATTGCTGAGTAGTATTCCA
TGGTATGGATGTACCACAGTTTGCTTAACCATTCACCCACTAAAGGACATAAGAGTTGTTTTCAGTTTTTTGCCCTAATAAAGCTGCTGT
GAACATTCATGTACAGGTTTTTATGTGAACATACATTTTCATTTTCTGGGATAAATGCTCAAAAGGGCAACTGTTGGGTTGTATGGTAAA
CACATATATTTTTGTAAGAAACTACCCTACTCTTTTTCCAGAGTGGCTCTACTTTTTACATACAGCCACTCATACAATTCAGACAGCAAT
GTATGATTGATCCAGTTTCTTCACATCCTCACCAGCATTTGGTATTACTACTATTTTTTATCTTAACCATTCACATAGATGTGTGTAATG
ATACCACATGTGGTTTTAATTTGCATTTCCAATGGCTAATGATGTTGAGTATCTTTTTGTGTGCTAATTTGCCATCTATGTATCCTCTTC
GGTGAAATGTCTTCATGTCTTTTGTCTATTTTCTATTTAGGTCATTTGTTCTTTTTACTATTGAGTTTTGAGAGGTTTTTTATATATCCT
AGATAAAATTCCTCTGTTAGATATGTGGTTGCTTGAATTTTTAACATAACTTCTACCAAGGAAAAATAAGTAAAATTTCCAACCCTTGCA
TGGCCAGTCACTTACTTAATTCCTGTCCTTCAGTGTTCCATCTAGAGAATTAAGAGATATGATGTATAAAATAGACATCGAGGGCCATTA
AGAGAGTAAATACTTAAAAATACATGTTATGAAAGCAAAGCCAATAATCACTGTAGGAGTATGAGTTGCCTAAGGGCCAAAACTAATGTA
AATAAGAGAAAGTGTGGATATAAATGACCATTGTTTATAAACAGTTATGAAAAATGCTGTGACTTGAAATCTTTCCCACATCTCCCAAGA
AAGTAGGTAGGAGTTTATCCTTTCCGTAATCTCTTTTTAACCCTGCTGACTATTACAGGGCTTGTTTAATCACAGTGGCAAGAATTACAT
GTATCTTACAGTAAAGAAACAGAATACTGGAATCGTTAGAGAACCCTGATGTGTTGACCTGGATAAAGTACAAAGGTGGAAGAGGGAATG
AGTTATGCTGTTAAAATCTCAGGCTATTCTGTTAATGTTCCTGCTACTATGAACCCAAACTTTTTTTTTCCCCCTTTTGACTCCTTGTGT
CTTCCTCTCCTGTGGCATAAAAGTAGTTCTGTCGTTAACTTGTACAACATTGCCATCTGCTGTTGAGAATTGGTAGGTACTGCTTCTGAG
AACCTGGCTGCAGATCCTTAGCATAGGCAGCAAATGTTGAGAAAGTCTATCTGTAGTATTACATATACTAAGTTACAGAGGATGCATCCA
AGTAGAGAAAATAATATGTGGGTTAAGATACATCCTTAAACTTTTTTTTTTTTGGGGGGGGGGGGACGGAGTCTTGCTGCAACGCCCAGG
CTGGAGTGCAATGGCACTATCTCAGCTCGCTGCAACCTTCACCTCCTGGGTTCAAGCAATTCTCCTGCCTCAGCCTCCTGAGTAGCTGGG
AATATAGGTGCACACCACCATGCCTGGCTAATTTTTGTATTTTCAGTAGAAGCAGAGTTTCACCATATTGGCCAGGTTGGTCTCGAACTC
CTGACCTCAAGTGATCTGCCTGCCTCAGCCTCCCAAAGTGCTGGGATTACACGCGTGAGCCACCACACCCAGCCTCCATCTTTAAACTTT
TAAATGTGAAATTTCTATCATGTACCGTTAGCCTAACAAGATTTTCTTTCCTATTTCTGACTGGTGCCTTTCCCCTTTTTAGGAGCAACG
AAAGCTACTCTCTTAGTTATGTTCTTGTGATGTGACAAAATGTCAAGAAGATAGGAGAAGAGAATATTTTATTTCGTTGATGCTTTTGTT
CCCAAGTGTGACCCTAAACTTAAGCTTTGTAGGAGTTGACATTCTTTCATGTCCCTTCCCTTTACTCATGCCGAAACTATCAACTGGGAC
ATTTTGTGCTTTTGGTTTAAAAGTTAATTGATATTATACTTTGGTTTTATCTAAAAAGTAAATGTATTTGCCTTTGACAAAAGACTGACA
CAAGAGCAAATAAGCTTTAAAATCGGGTGTTATGTGCTTTCCTCCATTTTTGAGCATATTATCCAAAATGGTCTGTATAATATAAATGAG
AATGATGCAGTTTAAGTAAGCCTTGTTATACCATTGTCATGGACCCCTGTCATAAAGCCATTTCTTGGTTTGTTTGGGAAAGAGGCATAT
GGGATTTATACAGATTCACTTGTAAATGTTGGATTGGGGATTTTTGTGTAAATTTTCTCAAATAAAGGCTAGCAGAAACCATTGCAAAAG
TTGAGAAGCTCAAACCATTAGAGGTAGAGCTGCGACGCCTAGAAGACCTTTCAGAATCTATTGTTAATGATTTTGCCTACATGAAGAAGA
GAGAAGAGGAGATGCGTGATACCAACGGAACAGGGCGGATACCTGACCAACTCGTGATCCTAGACATGAAGCATGGAGTGGAGGCGAAAA
ATTACGAAGAGATCACAGATTCTGCTGGCCATATTCTCTACTCCAAAGAGGATGCAACCAAGGGGAAATTTGCCTTTACCACTGAAGATT

>88038_88038_2_SULF1-TMED10_SULF1_chr8_70517136_ENST00000402687_TMED10_chr14_75643109_ENST00000303575_length(amino acids)=446AA_BP=
MKYSCCALVLAVLGTELLGSLCSTVRSPRFRGRIQQERKNIRPNIILVLTDDQDVELGSLQVMNKTRKIMEHGGATFINAFVTTPMCCPS
RSSMLTGKYVHNHNVYTNNENCSSPSWQAMHEPRTFAVYLNNTGYRTAFFGKYLNEYNGSYIPPGWREWLGLIKNSRFYNYTVCRNGIKE
KHGFDYAKDYFTDLITNESINYFKMSKRMYPHRPVMMVISHAAPHGPEDSAPQFSKLYPNASQHITPSYNYAPNMDKHWIMQYTGPMLPI
HMEFTNILQRKRLQTLMSVDDSVERLYNMLVETGELENTYIIYTADHGYHIGQFGLVKGKSMPYDFDIRVPFFIRGPSVEPGSIVPQIVL

--------------------------------------------------------------
>88038_88038_3_SULF1-TMED10_SULF1_chr8_70517136_ENST00000419716_TMED10_chr14_75643109_ENST00000303575_length(transcript)=5741nt_BP=1839nt
GTGATGATAATAATACGCGGGCTTATATAACCGTCTTCATCTTGCGAGCACTTCGCAGACCGTCGCTAATGAATCTTGGGGCCGGTGTCG
GGCCGGGGCGGCTTGATCGGCAACTAGGAAACCCCAGGCGCAGAGGCCAGGAGCGAGGGCAGCGAGGATCAGAGGCCAGGCCTTCCCGGC
TGCCGGCGCTCCTCGGAGGTCAGGGCAGATGAGGAACATGACTCTCCCCCTTCGGAGGAGGAAGGAAGTCCCGCTGCCACCTTATCTCTG
CTCCTCTGCCTCCTCCCTGTTCCCAGAGCTTTTTCTCTAGAGAAGATTTTGAAGGCGGCTTTTGTGCTGACGGCCACCCACCATCATCTA
AAGAAGATAAACTTGGCAAATGACATGCAGGTTCTTCAAGGCAGAATAATTGCAGAAAATCTTCAAAGGACCCTATCTGCAGATGTTCTG
AATACCTCTGAGAATAGAGATTGATTATTCAACCAGGATACCTAATTCAAGAACTCCAGAAATCAGGAGACGGAGACATTTTGTCAGTTT
TGCAACATTGGACCAAATACAATGAAGTATTCTTGCTGTGCTCTGGTTTTGGCTGTCCTGGGCACAGAATTGCTGGGAAGCCTCTGTTCG
ACTGTCAGATCCCCGAGGTTCAGAGGACGGATACAGCAGGAACGAAAAAACATCCGACCCAACATTATTCTTGTGCTTACCGATGATCAA
GATGTGGAGCTGGGGTCCCTGCAAGTCATGAACAAAACGAGAAAGATTATGGAACATGGGGGGGCCACCTTCATCAATGCCTTTGTGACT
ACACCCATGTGCTGCCCGTCACGGTCCTCCATGCTCACCGGGAAGTATGTGCACAATCACAATGTCTACACCAACAACGAGAACTGCTCT
TCCCCCTCGTGGCAGGCCATGCATGAGCCTCGGACTTTTGCTGTATATCTTAACAACACTGGCTACAGAACAGCCTTTTTTGGAAAATAC
CTCAATGAATATAATGGCAGCTACATCCCCCCTGGGTGGCGAGAATGGCTTGGATTAATCAAGAATTCTCGCTTCTATAATTACACTGTT
TGTCGCAATGGCATCAAAGAAAAGCATGGATTTGATTATGCAAAGGACTACTTCACAGACTTAATCACTAACGAGAGCATTAATTACTTC
AAAATGTCTAAGAGAATGTATCCCCATAGGCCCGTTATGATGGTGATCAGCCACGCTGCGCCCCACGGCCCCGAGGACTCAGCCCCACAG
TTTTCTAAACTGTACCCCAATGCTTCCCAACACATAACTCCTAGTTATAACTATGCACCAAATATGGATAAACACTGGATTATGCAGTAC
ACAGGACCAATGCTGCCCATCCACATGGAATTTACAAACATTCTACAGCGCAAAAGGCTCCAGACTTTGATGTCAGTGGATGATTCTGTG
GAGAGGCTGTATAACATGCTCGTGGAGACGGGGGAGCTGGAGAATACTTACATCATTTACACCGCCGACCATGGTTACCATATTGGGCAG
TTTGGACTGGTCAAGGGGAAATCCATGCCATATGACTTTGATATTCGTGTGCCTTTTTTTATTCGTGGTCCAAGTGTAGAACCAGGATCA
ATAGTCCCACAGATCGTTCTCAACATTGACTTGGCCCCCACGATCCTGGATATTGCTGGGCTCGACACACCTCCTGATGTGGACGGCAAG
TCTGTCCTCAAACTTCTGGACCCAGAAAAGCCAGGTAACAGGTTTCGAACAAACAAGAAGGCCAAAATTTGGCGTGATACATTCCTAGTG
GAAAGAGGGTACCAGACAGCCTGTGAACAACCGGGGCAGAGTCAACAAACACTCGGGTCCTATACTTCAGCATCTTTTCAATGTTCTGTC
TCATTGGACTAGCTACCTGGCAGGTCTTCTACCTGCGACGCTTCTTCAAGGCCAAGAAATTGATTGAGTAATGAATGAGGCATATTCTCC
TCCCACCTTGTACCTCAGCCAGCAGAACATCGCTGGGACGTGCCTGGCCTAAGGCATCCTACCAACAGCACCATCAAGGCACGTTGGAGC
TTTCTTGCCAGAACTGATCTCTTTTGGTGTGGGAGGACATGGGGTACCACCTACACCCAACAAGTCAATGAGGGACTTCTTTTTAATTTG
GTAGGATTTTGACTGGTTTTGCAACAATAGGTCTATTATTAGAGTCACCTATGACAAAAAATAGGGGTTACCTAGATAATGCCAAAGTCA
GCATTTGTCCTGGGTTCCCTTGTGTGATCTGTTTGGACTATGTTTTCTTTTCTTCTCCCACTTGCTCAGCAGCTTGGGCTTCCATTCTAG
TTCTTTTACCAAGATTTTTGTGTGACCATGTTGACTTCATTTGGATTGCCCTCTTTCAATTTCCTTGTGAAAACACCCTTAACTTTCTCT
TTACCCTTAGCTGAAATGTTTACATAGCTTCTGGTGATATCTTTTCATGATTTTATATCTCTTAAAATGGTGATGGATGTGACACCTCAT
AAAAGTGAGCTTTGAACTGTAGATAACTCTTAAAGAAAATGTCATTTTAGACAATTAAAATATTTGTGCTCAACTGCTTGAACTTTTTTC
GTGTATGTGTATTTAATTCTATGCAATATTATCACATGTGTAGATTCATGTGACCACCATCACAAGAGACAGAACAGTTCTGTCACATGG
ATCCCTTGCACTGCCCTTTTACAGCCGCAGCCACATCCCTTTCTTATACCCTCACCCCAACCTGTGGCTACCACTGTTCTGTCCTCCATC
TCTGTAATTTTGTCATTTCAAGAATGTTGTATGAATGGAATCATACAGAATGTAATCTTACGAGGCTGATCTTTTTTCATTCAGCATAAT
TCCCTTGAAATCCATCCAAGTTGTTGCATGTATGAATAGTTTCTTCCTTTTTTTCTTTTAAAAATGTTTTATATATTTAGGGGGTATAAG
TACAGATTTCTTACATGCATATATTGCATCGTGGTGAAGTGGGGGCAGTTCCTTTTGATTGCTGAGTAGTATTCCATGGTATGGATGTAC
CACAGTTTGCTTAACCATTCACCCACTAAAGGACATAAGAGTTGTTTTCAGTTTTTTGCCCTAATAAAGCTGCTGTGAACATTCATGTAC
AGGTTTTTATGTGAACATACATTTTCATTTTCTGGGATAAATGCTCAAAAGGGCAACTGTTGGGTTGTATGGTAAACACATATATTTTTG
TAAGAAACTACCCTACTCTTTTTCCAGAGTGGCTCTACTTTTTACATACAGCCACTCATACAATTCAGACAGCAATGTATGATTGATCCA
GTTTCTTCACATCCTCACCAGCATTTGGTATTACTACTATTTTTTATCTTAACCATTCACATAGATGTGTGTAATGATACCACATGTGGT
TTTAATTTGCATTTCCAATGGCTAATGATGTTGAGTATCTTTTTGTGTGCTAATTTGCCATCTATGTATCCTCTTCGGTGAAATGTCTTC
ATGTCTTTTGTCTATTTTCTATTTAGGTCATTTGTTCTTTTTACTATTGAGTTTTGAGAGGTTTTTTATATATCCTAGATAAAATTCCTC
TGTTAGATATGTGGTTGCTTGAATTTTTAACATAACTTCTACCAAGGAAAAATAAGTAAAATTTCCAACCCTTGCATGGCCAGTCACTTA
CTTAATTCCTGTCCTTCAGTGTTCCATCTAGAGAATTAAGAGATATGATGTATAAAATAGACATCGAGGGCCATTAAGAGAGTAAATACT
TAAAAATACATGTTATGAAAGCAAAGCCAATAATCACTGTAGGAGTATGAGTTGCCTAAGGGCCAAAACTAATGTAAATAAGAGAAAGTG
TGGATATAAATGACCATTGTTTATAAACAGTTATGAAAAATGCTGTGACTTGAAATCTTTCCCACATCTCCCAAGAAAGTAGGTAGGAGT
TTATCCTTTCCGTAATCTCTTTTTAACCCTGCTGACTATTACAGGGCTTGTTTAATCACAGTGGCAAGAATTACATGTATCTTACAGTAA
AGAAACAGAATACTGGAATCGTTAGAGAACCCTGATGTGTTGACCTGGATAAAGTACAAAGGTGGAAGAGGGAATGAGTTATGCTGTTAA
AATCTCAGGCTATTCTGTTAATGTTCCTGCTACTATGAACCCAAACTTTTTTTTTCCCCCTTTTGACTCCTTGTGTCTTCCTCTCCTGTG
GCATAAAAGTAGTTCTGTCGTTAACTTGTACAACATTGCCATCTGCTGTTGAGAATTGGTAGGTACTGCTTCTGAGAACCTGGCTGCAGA
TCCTTAGCATAGGCAGCAAATGTTGAGAAAGTCTATCTGTAGTATTACATATACTAAGTTACAGAGGATGCATCCAAGTAGAGAAAATAA
TATGTGGGTTAAGATACATCCTTAAACTTTTTTTTTTTTGGGGGGGGGGGGACGGAGTCTTGCTGCAACGCCCAGGCTGGAGTGCAATGG
CACTATCTCAGCTCGCTGCAACCTTCACCTCCTGGGTTCAAGCAATTCTCCTGCCTCAGCCTCCTGAGTAGCTGGGAATATAGGTGCACA
CCACCATGCCTGGCTAATTTTTGTATTTTCAGTAGAAGCAGAGTTTCACCATATTGGCCAGGTTGGTCTCGAACTCCTGACCTCAAGTGA
TCTGCCTGCCTCAGCCTCCCAAAGTGCTGGGATTACACGCGTGAGCCACCACACCCAGCCTCCATCTTTAAACTTTTAAATGTGAAATTT
CTATCATGTACCGTTAGCCTAACAAGATTTTCTTTCCTATTTCTGACTGGTGCCTTTCCCCTTTTTAGGAGCAACGAAAGCTACTCTCTT
AGTTATGTTCTTGTGATGTGACAAAATGTCAAGAAGATAGGAGAAGAGAATATTTTATTTCGTTGATGCTTTTGTTCCCAAGTGTGACCC
TAAACTTAAGCTTTGTAGGAGTTGACATTCTTTCATGTCCCTTCCCTTTACTCATGCCGAAACTATCAACTGGGACATTTTGTGCTTTTG
GTTTAAAAGTTAATTGATATTATACTTTGGTTTTATCTAAAAAGTAAATGTATTTGCCTTTGACAAAAGACTGACACAAGAGCAAATAAG
CTTTAAAATCGGGTGTTATGTGCTTTCCTCCATTTTTGAGCATATTATCCAAAATGGTCTGTATAATATAAATGAGAATGATGCAGTTTA
AGTAAGCCTTGTTATACCATTGTCATGGACCCCTGTCATAAAGCCATTTCTTGGTTTGTTTGGGAAAGAGGCATATGGGATTTATACAGA
TTCACTTGTAAATGTTGGATTGGGGATTTTTGTGTAAATTTTCTCAAATAAAGGCTAGCAGAAACCATTGCAAAAGTTGAGAAGCTCAAA
CCATTAGAGGTAGAGCTGCGACGCCTAGAAGACCTTTCAGAATCTATTGTTAATGATTTTGCCTACATGAAGAAGAGAGAAGAGGAGATG
CGTGATACCAACGGAACAGGGCGGATACCTGACCAACTCGTGATCCTAGACATGAAGCATGGAGTGGAGGCGAAAAATTACGAAGAGATC
ACAGATTCTGCTGGCCATATTCTCTACTCCAAAGAGGATGCAACCAAGGGGAAATTTGCCTTTACCACTGAAGATTATGACATGTTTGAA

>88038_88038_3_SULF1-TMED10_SULF1_chr8_70517136_ENST00000419716_TMED10_chr14_75643109_ENST00000303575_length(amino acids)=446AA_BP=
MKYSCCALVLAVLGTELLGSLCSTVRSPRFRGRIQQERKNIRPNIILVLTDDQDVELGSLQVMNKTRKIMEHGGATFINAFVTTPMCCPS
RSSMLTGKYVHNHNVYTNNENCSSPSWQAMHEPRTFAVYLNNTGYRTAFFGKYLNEYNGSYIPPGWREWLGLIKNSRFYNYTVCRNGIKE
KHGFDYAKDYFTDLITNESINYFKMSKRMYPHRPVMMVISHAAPHGPEDSAPQFSKLYPNASQHITPSYNYAPNMDKHWIMQYTGPMLPI
HMEFTNILQRKRLQTLMSVDDSVERLYNMLVETGELENTYIIYTADHGYHIGQFGLVKGKSMPYDFDIRVPFFIRGPSVEPGSIVPQIVL

--------------------------------------------------------------
>88038_88038_4_SULF1-TMED10_SULF1_chr8_70517136_ENST00000458141_TMED10_chr14_75643109_ENST00000303575_length(transcript)=5735nt_BP=1833nt
AGGTTACTTGACTGGGAGTTCTCAGACCTCCAGTTTCAGCCCTGCCCTCAGCCTCCAATCCGTAAGAGACACCCAGCCCCAGCAATTGGA
TTGGGCAGCCCGTCTTGACACACCACTGTGCTGAGTGCTTGAGGACGTGTTTCAACAGATGGTTGGGGTTAGTGTGTGTCATCACATTCG
AGTGGGGATTAAGAGAAGGAAGGCTGCCTTGCTGGAGCTGTGTGGTCTTCTCCAAGTGAGAGTCGCAGGCAATAGAACTACTTTGCTTTT
GGAGGAAAAGGAGGAATTCATTTTCAGCAGACACAAGAAAAGCAGTTTTTTTTTCAGGTGCTGACGGCCACCCACCATCATCTAAAGAAG
ATAAACTTGGCAAATGACATGCAGGTTCTTCAAGGCAGAATAATTGCAGAAAATCTTCAAAGGACCCTATCTGCAGATGTTCTGAATACC
TCTGAGAATAGAGATTGATTATTCAACCAGGATACCTAATTCAAGAACTCCAGAAATCAGGAGACGGAGACATTTTGTCAGTTTTGCAAC
ATTGGACCAAATACAATGAAGTATTCTTGCTGTGCTCTGGTTTTGGCTGTCCTGGGCACAGAATTGCTGGGAAGCCTCTGTTCGACTGTC
AGATCCCCGAGGTTCAGAGGACGGATACAGCAGGAACGAAAAAACATCCGACCCAACATTATTCTTGTGCTTACCGATGATCAAGATGTG
GAGCTGGGGTCCCTGCAAGTCATGAACAAAACGAGAAAGATTATGGAACATGGGGGGGCCACCTTCATCAATGCCTTTGTGACTACACCC
ATGTGCTGCCCGTCACGGTCCTCCATGCTCACCGGGAAGTATGTGCACAATCACAATGTCTACACCAACAACGAGAACTGCTCTTCCCCC
TCGTGGCAGGCCATGCATGAGCCTCGGACTTTTGCTGTATATCTTAACAACACTGGCTACAGAACAGCCTTTTTTGGAAAATACCTCAAT
GAATATAATGGCAGCTACATCCCCCCTGGGTGGCGAGAATGGCTTGGATTAATCAAGAATTCTCGCTTCTATAATTACACTGTTTGTCGC
AATGGCATCAAAGAAAAGCATGGATTTGATTATGCAAAGGACTACTTCACAGACTTAATCACTAACGAGAGCATTAATTACTTCAAAATG
TCTAAGAGAATGTATCCCCATAGGCCCGTTATGATGGTGATCAGCCACGCTGCGCCCCACGGCCCCGAGGACTCAGCCCCACAGTTTTCT
AAACTGTACCCCAATGCTTCCCAACACATAACTCCTAGTTATAACTATGCACCAAATATGGATAAACACTGGATTATGCAGTACACAGGA
CCAATGCTGCCCATCCACATGGAATTTACAAACATTCTACAGCGCAAAAGGCTCCAGACTTTGATGTCAGTGGATGATTCTGTGGAGAGG
CTGTATAACATGCTCGTGGAGACGGGGGAGCTGGAGAATACTTACATCATTTACACCGCCGACCATGGTTACCATATTGGGCAGTTTGGA
CTGGTCAAGGGGAAATCCATGCCATATGACTTTGATATTCGTGTGCCTTTTTTTATTCGTGGTCCAAGTGTAGAACCAGGATCAATAGTC
CCACAGATCGTTCTCAACATTGACTTGGCCCCCACGATCCTGGATATTGCTGGGCTCGACACACCTCCTGATGTGGACGGCAAGTCTGTC
CTCAAACTTCTGGACCCAGAAAAGCCAGGTAACAGGTTTCGAACAAACAAGAAGGCCAAAATTTGGCGTGATACATTCCTAGTGGAAAGA
GGGTACCAGACAGCCTGTGAACAACCGGGGCAGAGTCAACAAACACTCGGGTCCTATACTTCAGCATCTTTTCAATGTTCTGTCTCATTG
GACTAGCTACCTGGCAGGTCTTCTACCTGCGACGCTTCTTCAAGGCCAAGAAATTGATTGAGTAATGAATGAGGCATATTCTCCTCCCAC
CTTGTACCTCAGCCAGCAGAACATCGCTGGGACGTGCCTGGCCTAAGGCATCCTACCAACAGCACCATCAAGGCACGTTGGAGCTTTCTT
GCCAGAACTGATCTCTTTTGGTGTGGGAGGACATGGGGTACCACCTACACCCAACAAGTCAATGAGGGACTTCTTTTTAATTTGGTAGGA
TTTTGACTGGTTTTGCAACAATAGGTCTATTATTAGAGTCACCTATGACAAAAAATAGGGGTTACCTAGATAATGCCAAAGTCAGCATTT
GTCCTGGGTTCCCTTGTGTGATCTGTTTGGACTATGTTTTCTTTTCTTCTCCCACTTGCTCAGCAGCTTGGGCTTCCATTCTAGTTCTTT
TACCAAGATTTTTGTGTGACCATGTTGACTTCATTTGGATTGCCCTCTTTCAATTTCCTTGTGAAAACACCCTTAACTTTCTCTTTACCC
TTAGCTGAAATGTTTACATAGCTTCTGGTGATATCTTTTCATGATTTTATATCTCTTAAAATGGTGATGGATGTGACACCTCATAAAAGT
GAGCTTTGAACTGTAGATAACTCTTAAAGAAAATGTCATTTTAGACAATTAAAATATTTGTGCTCAACTGCTTGAACTTTTTTCGTGTAT
GTGTATTTAATTCTATGCAATATTATCACATGTGTAGATTCATGTGACCACCATCACAAGAGACAGAACAGTTCTGTCACATGGATCCCT
TGCACTGCCCTTTTACAGCCGCAGCCACATCCCTTTCTTATACCCTCACCCCAACCTGTGGCTACCACTGTTCTGTCCTCCATCTCTGTA
ATTTTGTCATTTCAAGAATGTTGTATGAATGGAATCATACAGAATGTAATCTTACGAGGCTGATCTTTTTTCATTCAGCATAATTCCCTT
GAAATCCATCCAAGTTGTTGCATGTATGAATAGTTTCTTCCTTTTTTTCTTTTAAAAATGTTTTATATATTTAGGGGGTATAAGTACAGA
TTTCTTACATGCATATATTGCATCGTGGTGAAGTGGGGGCAGTTCCTTTTGATTGCTGAGTAGTATTCCATGGTATGGATGTACCACAGT
TTGCTTAACCATTCACCCACTAAAGGACATAAGAGTTGTTTTCAGTTTTTTGCCCTAATAAAGCTGCTGTGAACATTCATGTACAGGTTT
TTATGTGAACATACATTTTCATTTTCTGGGATAAATGCTCAAAAGGGCAACTGTTGGGTTGTATGGTAAACACATATATTTTTGTAAGAA
ACTACCCTACTCTTTTTCCAGAGTGGCTCTACTTTTTACATACAGCCACTCATACAATTCAGACAGCAATGTATGATTGATCCAGTTTCT
TCACATCCTCACCAGCATTTGGTATTACTACTATTTTTTATCTTAACCATTCACATAGATGTGTGTAATGATACCACATGTGGTTTTAAT
TTGCATTTCCAATGGCTAATGATGTTGAGTATCTTTTTGTGTGCTAATTTGCCATCTATGTATCCTCTTCGGTGAAATGTCTTCATGTCT
TTTGTCTATTTTCTATTTAGGTCATTTGTTCTTTTTACTATTGAGTTTTGAGAGGTTTTTTATATATCCTAGATAAAATTCCTCTGTTAG
ATATGTGGTTGCTTGAATTTTTAACATAACTTCTACCAAGGAAAAATAAGTAAAATTTCCAACCCTTGCATGGCCAGTCACTTACTTAAT
TCCTGTCCTTCAGTGTTCCATCTAGAGAATTAAGAGATATGATGTATAAAATAGACATCGAGGGCCATTAAGAGAGTAAATACTTAAAAA
TACATGTTATGAAAGCAAAGCCAATAATCACTGTAGGAGTATGAGTTGCCTAAGGGCCAAAACTAATGTAAATAAGAGAAAGTGTGGATA
TAAATGACCATTGTTTATAAACAGTTATGAAAAATGCTGTGACTTGAAATCTTTCCCACATCTCCCAAGAAAGTAGGTAGGAGTTTATCC
TTTCCGTAATCTCTTTTTAACCCTGCTGACTATTACAGGGCTTGTTTAATCACAGTGGCAAGAATTACATGTATCTTACAGTAAAGAAAC
AGAATACTGGAATCGTTAGAGAACCCTGATGTGTTGACCTGGATAAAGTACAAAGGTGGAAGAGGGAATGAGTTATGCTGTTAAAATCTC
AGGCTATTCTGTTAATGTTCCTGCTACTATGAACCCAAACTTTTTTTTTCCCCCTTTTGACTCCTTGTGTCTTCCTCTCCTGTGGCATAA
AAGTAGTTCTGTCGTTAACTTGTACAACATTGCCATCTGCTGTTGAGAATTGGTAGGTACTGCTTCTGAGAACCTGGCTGCAGATCCTTA
GCATAGGCAGCAAATGTTGAGAAAGTCTATCTGTAGTATTACATATACTAAGTTACAGAGGATGCATCCAAGTAGAGAAAATAATATGTG
GGTTAAGATACATCCTTAAACTTTTTTTTTTTTGGGGGGGGGGGGACGGAGTCTTGCTGCAACGCCCAGGCTGGAGTGCAATGGCACTAT
CTCAGCTCGCTGCAACCTTCACCTCCTGGGTTCAAGCAATTCTCCTGCCTCAGCCTCCTGAGTAGCTGGGAATATAGGTGCACACCACCA
TGCCTGGCTAATTTTTGTATTTTCAGTAGAAGCAGAGTTTCACCATATTGGCCAGGTTGGTCTCGAACTCCTGACCTCAAGTGATCTGCC
TGCCTCAGCCTCCCAAAGTGCTGGGATTACACGCGTGAGCCACCACACCCAGCCTCCATCTTTAAACTTTTAAATGTGAAATTTCTATCA
TGTACCGTTAGCCTAACAAGATTTTCTTTCCTATTTCTGACTGGTGCCTTTCCCCTTTTTAGGAGCAACGAAAGCTACTCTCTTAGTTAT
GTTCTTGTGATGTGACAAAATGTCAAGAAGATAGGAGAAGAGAATATTTTATTTCGTTGATGCTTTTGTTCCCAAGTGTGACCCTAAACT
TAAGCTTTGTAGGAGTTGACATTCTTTCATGTCCCTTCCCTTTACTCATGCCGAAACTATCAACTGGGACATTTTGTGCTTTTGGTTTAA
AAGTTAATTGATATTATACTTTGGTTTTATCTAAAAAGTAAATGTATTTGCCTTTGACAAAAGACTGACACAAGAGCAAATAAGCTTTAA
AATCGGGTGTTATGTGCTTTCCTCCATTTTTGAGCATATTATCCAAAATGGTCTGTATAATATAAATGAGAATGATGCAGTTTAAGTAAG
CCTTGTTATACCATTGTCATGGACCCCTGTCATAAAGCCATTTCTTGGTTTGTTTGGGAAAGAGGCATATGGGATTTATACAGATTCACT
TGTAAATGTTGGATTGGGGATTTTTGTGTAAATTTTCTCAAATAAAGGCTAGCAGAAACCATTGCAAAAGTTGAGAAGCTCAAACCATTA
GAGGTAGAGCTGCGACGCCTAGAAGACCTTTCAGAATCTATTGTTAATGATTTTGCCTACATGAAGAAGAGAGAAGAGGAGATGCGTGAT
ACCAACGGAACAGGGCGGATACCTGACCAACTCGTGATCCTAGACATGAAGCATGGAGTGGAGGCGAAAAATTACGAAGAGATCACAGAT
TCTGCTGGCCATATTCTCTACTCCAAAGAGGATGCAACCAAGGGGAAATTTGCCTTTACCACTGAAGATTATGACATGTTTGAAGTGTGT

>88038_88038_4_SULF1-TMED10_SULF1_chr8_70517136_ENST00000458141_TMED10_chr14_75643109_ENST00000303575_length(amino acids)=446AA_BP=
MKYSCCALVLAVLGTELLGSLCSTVRSPRFRGRIQQERKNIRPNIILVLTDDQDVELGSLQVMNKTRKIMEHGGATFINAFVTTPMCCPS
RSSMLTGKYVHNHNVYTNNENCSSPSWQAMHEPRTFAVYLNNTGYRTAFFGKYLNEYNGSYIPPGWREWLGLIKNSRFYNYTVCRNGIKE
KHGFDYAKDYFTDLITNESINYFKMSKRMYPHRPVMMVISHAAPHGPEDSAPQFSKLYPNASQHITPSYNYAPNMDKHWIMQYTGPMLPI
HMEFTNILQRKRLQTLMSVDDSVERLYNMLVETGELENTYIIYTADHGYHIGQFGLVKGKSMPYDFDIRVPFFIRGPSVEPGSIVPQIVL

--------------------------------------------------------------
>88038_88038_5_SULF1-TMED10_SULF1_chr8_70517137_ENST00000260128_TMED10_chr14_75643112_ENST00000303575_length(transcript)=5899nt_BP=1994nt
AGGTTACTTGACTGGGAGTTCTCAGACCTCCAGTTTCAGCCCTGCCCTCAGCCTCCAATCCGTAAGAGACACCCAGCCCCAGCAATTGGA
TTGGGCAGCCCGTCTTGACACACCACTGTGCTGAGTGCTTGAGGACGTGTTTCAACAGATGGTTGGGGTTAGTGTGTGTCATCACATTCG
AGTGGGGATTAAGAGAAGGAAGGCTGCCTTGCTGGAGCTGTGTGGTCTTCTCCAAGTGAGAGTCGCAGGCAATAGAACTACTTTGCTTTT
GGAGGAAAAGGAGGAATTCATTTTCAGCAGACACAAGAAAAGCAGTTTTTTTTTCAGGGATTCTTCACTTCTCTTGAACAAGGAACTCAC
TCAGAGACTAACACAAAGGAAGTAATTTCTTACCTGGTCATTATTTAGTCTACAATAAGTTCATCCTTCTTCAGTGTGACCAGTAAATTC
TTCCCATACTCTTGAAGAGAGCATAATTGGAATGGAGAGGTGCTGACGGCCACCCACCATCATCTAAAGAAGATAAACTTGGCAAATGAC
ATGCAGGTTCTTCAAGGCAGAATAATTGCAGAAAATCTTCAAAGGACCCTATCTGCAGATGTTCTGAATACCTCTGAGAATAGAGATTGA
TTATTCAACCAGGATACCTAATTCAAGAACTCCAGAAATCAGGAGACGGAGACATTTTGTCAGTTTTGCAACATTGGACCAAATACAATG
AAGTATTCTTGCTGTGCTCTGGTTTTGGCTGTCCTGGGCACAGAATTGCTGGGAAGCCTCTGTTCGACTGTCAGATCCCCGAGGTTCAGA
GGACGGATACAGCAGGAACGAAAAAACATCCGACCCAACATTATTCTTGTGCTTACCGATGATCAAGATGTGGAGCTGGGGTCCCTGCAA
GTCATGAACAAAACGAGAAAGATTATGGAACATGGGGGGGCCACCTTCATCAATGCCTTTGTGACTACACCCATGTGCTGCCCGTCACGG
TCCTCCATGCTCACCGGGAAGTATGTGCACAATCACAATGTCTACACCAACAACGAGAACTGCTCTTCCCCCTCGTGGCAGGCCATGCAT
GAGCCTCGGACTTTTGCTGTATATCTTAACAACACTGGCTACAGAACAGCCTTTTTTGGAAAATACCTCAATGAATATAATGGCAGCTAC
ATCCCCCCTGGGTGGCGAGAATGGCTTGGATTAATCAAGAATTCTCGCTTCTATAATTACACTGTTTGTCGCAATGGCATCAAAGAAAAG
CATGGATTTGATTATGCAAAGGACTACTTCACAGACTTAATCACTAACGAGAGCATTAATTACTTCAAAATGTCTAAGAGAATGTATCCC
CATAGGCCCGTTATGATGGTGATCAGCCACGCTGCGCCCCACGGCCCCGAGGACTCAGCCCCACAGTTTTCTAAACTGTACCCCAATGCT
TCCCAACACATAACTCCTAGTTATAACTATGCACCAAATATGGATAAACACTGGATTATGCAGTACACAGGACCAATGCTGCCCATCCAC
ATGGAATTTACAAACATTCTACAGCGCAAAAGGCTCCAGACTTTGATGTCAGTGGATGATTCTGTGGAGAGGCTGTATAACATGCTCGTG
GAGACGGGGGAGCTGGAGAATACTTACATCATTTACACCGCCGACCATGGTTACCATATTGGGCAGTTTGGACTGGTCAAGGGGAAATCC
ATGCCATATGACTTTGATATTCGTGTGCCTTTTTTTATTCGTGGTCCAAGTGTAGAACCAGGATCAATAGTCCCACAGATCGTTCTCAAC
ATTGACTTGGCCCCCACGATCCTGGATATTGCTGGGCTCGACACACCTCCTGATGTGGACGGCAAGTCTGTCCTCAAACTTCTGGACCCA
GAAAAGCCAGGTAACAGGTTTCGAACAAACAAGAAGGCCAAAATTTGGCGTGATACATTCCTAGTGGAAAGAGGTACCAGACAGCCTGTG
AACAACCGGGGCAGAGTCAACAAACACTCGGGTCCTATACTTCAGCATCTTTTCAATGTTCTGTCTCATTGGACTAGCTACCTGGCAGGT
CTTCTACCTGCGACGCTTCTTCAAGGCCAAGAAATTGATTGAGTAATGAATGAGGCATATTCTCCTCCCACCTTGTACCTCAGCCAGCAG
AACATCGCTGGGACGTGCCTGGCCTAAGGCATCCTACCAACAGCACCATCAAGGCACGTTGGAGCTTTCTTGCCAGAACTGATCTCTTTT
GGTGTGGGAGGACATGGGGTACCACCTACACCCAACAAGTCAATGAGGGACTTCTTTTTAATTTGGTAGGATTTTGACTGGTTTTGCAAC
AATAGGTCTATTATTAGAGTCACCTATGACAAAAAATAGGGGTTACCTAGATAATGCCAAAGTCAGCATTTGTCCTGGGTTCCCTTGTGT
GATCTGTTTGGACTATGTTTTCTTTTCTTCTCCCACTTGCTCAGCAGCTTGGGCTTCCATTCTAGTTCTTTTACCAAGATTTTTGTGTGA
CCATGTTGACTTCATTTGGATTGCCCTCTTTCAATTTCCTTGTGAAAACACCCTTAACTTTCTCTTTACCCTTAGCTGAAATGTTTACAT
AGCTTCTGGTGATATCTTTTCATGATTTTATATCTCTTAAAATGGTGATGGATGTGACACCTCATAAAAGTGAGCTTTGAACTGTAGATA
ACTCTTAAAGAAAATGTCATTTTAGACAATTAAAATATTTGTGCTCAACTGCTTGAACTTTTTTCGTGTATGTGTATTTAATTCTATGCA
ATATTATCACATGTGTAGATTCATGTGACCACCATCACAAGAGACAGAACAGTTCTGTCACATGGATCCCTTGCACTGCCCTTTTACAGC
CGCAGCCACATCCCTTTCTTATACCCTCACCCCAACCTGTGGCTACCACTGTTCTGTCCTCCATCTCTGTAATTTTGTCATTTCAAGAAT
GTTGTATGAATGGAATCATACAGAATGTAATCTTACGAGGCTGATCTTTTTTCATTCAGCATAATTCCCTTGAAATCCATCCAAGTTGTT
GCATGTATGAATAGTTTCTTCCTTTTTTTCTTTTAAAAATGTTTTATATATTTAGGGGGTATAAGTACAGATTTCTTACATGCATATATT
GCATCGTGGTGAAGTGGGGGCAGTTCCTTTTGATTGCTGAGTAGTATTCCATGGTATGGATGTACCACAGTTTGCTTAACCATTCACCCA
CTAAAGGACATAAGAGTTGTTTTCAGTTTTTTGCCCTAATAAAGCTGCTGTGAACATTCATGTACAGGTTTTTATGTGAACATACATTTT
CATTTTCTGGGATAAATGCTCAAAAGGGCAACTGTTGGGTTGTATGGTAAACACATATATTTTTGTAAGAAACTACCCTACTCTTTTTCC
AGAGTGGCTCTACTTTTTACATACAGCCACTCATACAATTCAGACAGCAATGTATGATTGATCCAGTTTCTTCACATCCTCACCAGCATT
TGGTATTACTACTATTTTTTATCTTAACCATTCACATAGATGTGTGTAATGATACCACATGTGGTTTTAATTTGCATTTCCAATGGCTAA
TGATGTTGAGTATCTTTTTGTGTGCTAATTTGCCATCTATGTATCCTCTTCGGTGAAATGTCTTCATGTCTTTTGTCTATTTTCTATTTA
GGTCATTTGTTCTTTTTACTATTGAGTTTTGAGAGGTTTTTTATATATCCTAGATAAAATTCCTCTGTTAGATATGTGGTTGCTTGAATT
TTTAACATAACTTCTACCAAGGAAAAATAAGTAAAATTTCCAACCCTTGCATGGCCAGTCACTTACTTAATTCCTGTCCTTCAGTGTTCC
ATCTAGAGAATTAAGAGATATGATGTATAAAATAGACATCGAGGGCCATTAAGAGAGTAAATACTTAAAAATACATGTTATGAAAGCAAA
GCCAATAATCACTGTAGGAGTATGAGTTGCCTAAGGGCCAAAACTAATGTAAATAAGAGAAAGTGTGGATATAAATGACCATTGTTTATA
AACAGTTATGAAAAATGCTGTGACTTGAAATCTTTCCCACATCTCCCAAGAAAGTAGGTAGGAGTTTATCCTTTCCGTAATCTCTTTTTA
ACCCTGCTGACTATTACAGGGCTTGTTTAATCACAGTGGCAAGAATTACATGTATCTTACAGTAAAGAAACAGAATACTGGAATCGTTAG
AGAACCCTGATGTGTTGACCTGGATAAAGTACAAAGGTGGAAGAGGGAATGAGTTATGCTGTTAAAATCTCAGGCTATTCTGTTAATGTT
CCTGCTACTATGAACCCAAACTTTTTTTTTCCCCCTTTTGACTCCTTGTGTCTTCCTCTCCTGTGGCATAAAAGTAGTTCTGTCGTTAAC
TTGTACAACATTGCCATCTGCTGTTGAGAATTGGTAGGTACTGCTTCTGAGAACCTGGCTGCAGATCCTTAGCATAGGCAGCAAATGTTG
AGAAAGTCTATCTGTAGTATTACATATACTAAGTTACAGAGGATGCATCCAAGTAGAGAAAATAATATGTGGGTTAAGATACATCCTTAA
ACTTTTTTTTTTTTGGGGGGGGGGGGACGGAGTCTTGCTGCAACGCCCAGGCTGGAGTGCAATGGCACTATCTCAGCTCGCTGCAACCTT
CACCTCCTGGGTTCAAGCAATTCTCCTGCCTCAGCCTCCTGAGTAGCTGGGAATATAGGTGCACACCACCATGCCTGGCTAATTTTTGTA
TTTTCAGTAGAAGCAGAGTTTCACCATATTGGCCAGGTTGGTCTCGAACTCCTGACCTCAAGTGATCTGCCTGCCTCAGCCTCCCAAAGT
GCTGGGATTACACGCGTGAGCCACCACACCCAGCCTCCATCTTTAAACTTTTAAATGTGAAATTTCTATCATGTACCGTTAGCCTAACAA
GATTTTCTTTCCTATTTCTGACTGGTGCCTTTCCCCTTTTTAGGAGCAACGAAAGCTACTCTCTTAGTTATGTTCTTGTGATGTGACAAA
ATGTCAAGAAGATAGGAGAAGAGAATATTTTATTTCGTTGATGCTTTTGTTCCCAAGTGTGACCCTAAACTTAAGCTTTGTAGGAGTTGA
CATTCTTTCATGTCCCTTCCCTTTACTCATGCCGAAACTATCAACTGGGACATTTTGTGCTTTTGGTTTAAAAGTTAATTGATATTATAC
TTTGGTTTTATCTAAAAAGTAAATGTATTTGCCTTTGACAAAAGACTGACACAAGAGCAAATAAGCTTTAAAATCGGGTGTTATGTGCTT
TCCTCCATTTTTGAGCATATTATCCAAAATGGTCTGTATAATATAAATGAGAATGATGCAGTTTAAGTAAGCCTTGTTATACCATTGTCA
TGGACCCCTGTCATAAAGCCATTTCTTGGTTTGTTTGGGAAAGAGGCATATGGGATTTATACAGATTCACTTGTAAATGTTGGATTGGGG
ATTTTTGTGTAAATTTTCTCAAATAAAGGCTAGCAGAAACCATTGCAAAAGTTGAGAAGCTCAAACCATTAGAGGTAGAGCTGCGACGCC
TAGAAGACCTTTCAGAATCTATTGTTAATGATTTTGCCTACATGAAGAAGAGAGAAGAGGAGATGCGTGATACCAACGGAACAGGGCGGA
TACCTGACCAACTCGTGATCCTAGACATGAAGCATGGAGTGGAGGCGAAAAATTACGAAGAGATCACAGATTCTGCTGGCCATATTCTCT
ACTCCAAAGAGGATGCAACCAAGGGGAAATTTGCCTTTACCACTGAAGATTATGACATGTTTGAAGTGTGTTTTGAGAGCAAGGGTACGA

>88038_88038_5_SULF1-TMED10_SULF1_chr8_70517137_ENST00000260128_TMED10_chr14_75643112_ENST00000303575_length(amino acids)=464AA_BP=
MKYSCCALVLAVLGTELLGSLCSTVRSPRFRGRIQQERKNIRPNIILVLTDDQDVELGSLQVMNKTRKIMEHGGATFINAFVTTPMCCPS
RSSMLTGKYVHNHNVYTNNENCSSPSWQAMHEPRTFAVYLNNTGYRTAFFGKYLNEYNGSYIPPGWREWLGLIKNSRFYNYTVCRNGIKE
KHGFDYAKDYFTDLITNESINYFKMSKRMYPHRPVMMVISHAAPHGPEDSAPQFSKLYPNASQHITPSYNYAPNMDKHWIMQYTGPMLPI
HMEFTNILQRKRLQTLMSVDDSVERLYNMLVETGELENTYIIYTADHGYHIGQFGLVKGKSMPYDFDIRVPFFIRGPSVEPGSIVPQIVL
NIDLAPTILDIAGLDTPPDVDGKSVLKLLDPEKPGNRFRTNKKAKIWRDTFLVERGTRQPVNNRGRVNKHSGPILQHLFNVLSHWTSYLA

--------------------------------------------------------------
>88038_88038_6_SULF1-TMED10_SULF1_chr8_70517137_ENST00000402687_TMED10_chr14_75643112_ENST00000303575_length(transcript)=5937nt_BP=2032nt
TTTGTCTGGCAGCGTTGGTTCTATGGGGGTGTGTGATGATAATAATACGCGGGCTTATATAACCGTCTTCATCTTGCGAGCACTTCGCAG
ACCGTCGCTAATGAATCTTGGGGCCGGTGTCGGGCCGGGGCGGCTTGATCGGCAACTAGGAAACCCCAGGCGCAGAGGCCAGGAGCGAGG
GCAGCGAGGATCAGAGGCCAGGCCTTCCCGGCTGCCGGCGCTCCTCGGAGGTCAGGGCAGATGAGGAACATGACTCTCCCCCTTCGGAGG
AGGAAGGAAGTCCCGCTGCCACCTTATCTCTGCTCCTCTGCCTCCTCCCTGTTCCCAGAGCTTTTTCTCTAGAGAAGATTTTGAAGGCGG
CTTTTGGATTCTTCACTTCTCTTGAACAAGGAACTCACTCAGAGACTAACACAAAGGAAGTAATTTCTTACCTGGTCATTATTTAGTCTA
CAATAAGTTCATCCTTCTTCAGTGTGACCAGTAAATTCTTCCCATACTCTTGAAGAGAGCATAATTGGAATGGAGAGGTGCTGACGGCCA
CCCACCATCATCTAAAGAAGATAAACTTGGCAAATGACATGCAGGTTCTTCAAGGCAGAATAATTGCAGAAAATCTTCAAAGGACCCTAT
CTGCAGATGTTCTGAATACCTCTGAGAATAGAGATTGATTATTCAACCAGGATACCTAATTCAAGAACTCCAGAAATCAGGAGACGGAGA
CATTTTGTCAGTTTTGCAACATTGGACCAAATACAATGAAGTATTCTTGCTGTGCTCTGGTTTTGGCTGTCCTGGGCACAGAATTGCTGG
GAAGCCTCTGTTCGACTGTCAGATCCCCGAGGTTCAGAGGACGGATACAGCAGGAACGAAAAAACATCCGACCCAACATTATTCTTGTGC
TTACCGATGATCAAGATGTGGAGCTGGGGTCCCTGCAAGTCATGAACAAAACGAGAAAGATTATGGAACATGGGGGGGCCACCTTCATCA
ATGCCTTTGTGACTACACCCATGTGCTGCCCGTCACGGTCCTCCATGCTCACCGGGAAGTATGTGCACAATCACAATGTCTACACCAACA
ACGAGAACTGCTCTTCCCCCTCGTGGCAGGCCATGCATGAGCCTCGGACTTTTGCTGTATATCTTAACAACACTGGCTACAGAACAGCCT
TTTTTGGAAAATACCTCAATGAATATAATGGCAGCTACATCCCCCCTGGGTGGCGAGAATGGCTTGGATTAATCAAGAATTCTCGCTTCT
ATAATTACACTGTTTGTCGCAATGGCATCAAAGAAAAGCATGGATTTGATTATGCAAAGGACTACTTCACAGACTTAATCACTAACGAGA
GCATTAATTACTTCAAAATGTCTAAGAGAATGTATCCCCATAGGCCCGTTATGATGGTGATCAGCCACGCTGCGCCCCACGGCCCCGAGG
ACTCAGCCCCACAGTTTTCTAAACTGTACCCCAATGCTTCCCAACACATAACTCCTAGTTATAACTATGCACCAAATATGGATAAACACT
GGATTATGCAGTACACAGGACCAATGCTGCCCATCCACATGGAATTTACAAACATTCTACAGCGCAAAAGGCTCCAGACTTTGATGTCAG
TGGATGATTCTGTGGAGAGGCTGTATAACATGCTCGTGGAGACGGGGGAGCTGGAGAATACTTACATCATTTACACCGCCGACCATGGTT
ACCATATTGGGCAGTTTGGACTGGTCAAGGGGAAATCCATGCCATATGACTTTGATATTCGTGTGCCTTTTTTTATTCGTGGTCCAAGTG
TAGAACCAGGATCAATAGTCCCACAGATCGTTCTCAACATTGACTTGGCCCCCACGATCCTGGATATTGCTGGGCTCGACACACCTCCTG
ATGTGGACGGCAAGTCTGTCCTCAAACTTCTGGACCCAGAAAAGCCAGGTAACAGGTTTCGAACAAACAAGAAGGCCAAAATTTGGCGTG
ATACATTCCTAGTGGAAAGAGGTACCAGACAGCCTGTGAACAACCGGGGCAGAGTCAACAAACACTCGGGTCCTATACTTCAGCATCTTT
TCAATGTTCTGTCTCATTGGACTAGCTACCTGGCAGGTCTTCTACCTGCGACGCTTCTTCAAGGCCAAGAAATTGATTGAGTAATGAATG
AGGCATATTCTCCTCCCACCTTGTACCTCAGCCAGCAGAACATCGCTGGGACGTGCCTGGCCTAAGGCATCCTACCAACAGCACCATCAA
GGCACGTTGGAGCTTTCTTGCCAGAACTGATCTCTTTTGGTGTGGGAGGACATGGGGTACCACCTACACCCAACAAGTCAATGAGGGACT
TCTTTTTAATTTGGTAGGATTTTGACTGGTTTTGCAACAATAGGTCTATTATTAGAGTCACCTATGACAAAAAATAGGGGTTACCTAGAT
AATGCCAAAGTCAGCATTTGTCCTGGGTTCCCTTGTGTGATCTGTTTGGACTATGTTTTCTTTTCTTCTCCCACTTGCTCAGCAGCTTGG
GCTTCCATTCTAGTTCTTTTACCAAGATTTTTGTGTGACCATGTTGACTTCATTTGGATTGCCCTCTTTCAATTTCCTTGTGAAAACACC
CTTAACTTTCTCTTTACCCTTAGCTGAAATGTTTACATAGCTTCTGGTGATATCTTTTCATGATTTTATATCTCTTAAAATGGTGATGGA
TGTGACACCTCATAAAAGTGAGCTTTGAACTGTAGATAACTCTTAAAGAAAATGTCATTTTAGACAATTAAAATATTTGTGCTCAACTGC
TTGAACTTTTTTCGTGTATGTGTATTTAATTCTATGCAATATTATCACATGTGTAGATTCATGTGACCACCATCACAAGAGACAGAACAG
TTCTGTCACATGGATCCCTTGCACTGCCCTTTTACAGCCGCAGCCACATCCCTTTCTTATACCCTCACCCCAACCTGTGGCTACCACTGT
TCTGTCCTCCATCTCTGTAATTTTGTCATTTCAAGAATGTTGTATGAATGGAATCATACAGAATGTAATCTTACGAGGCTGATCTTTTTT
CATTCAGCATAATTCCCTTGAAATCCATCCAAGTTGTTGCATGTATGAATAGTTTCTTCCTTTTTTTCTTTTAAAAATGTTTTATATATT
TAGGGGGTATAAGTACAGATTTCTTACATGCATATATTGCATCGTGGTGAAGTGGGGGCAGTTCCTTTTGATTGCTGAGTAGTATTCCAT
GGTATGGATGTACCACAGTTTGCTTAACCATTCACCCACTAAAGGACATAAGAGTTGTTTTCAGTTTTTTGCCCTAATAAAGCTGCTGTG
AACATTCATGTACAGGTTTTTATGTGAACATACATTTTCATTTTCTGGGATAAATGCTCAAAAGGGCAACTGTTGGGTTGTATGGTAAAC
ACATATATTTTTGTAAGAAACTACCCTACTCTTTTTCCAGAGTGGCTCTACTTTTTACATACAGCCACTCATACAATTCAGACAGCAATG
TATGATTGATCCAGTTTCTTCACATCCTCACCAGCATTTGGTATTACTACTATTTTTTATCTTAACCATTCACATAGATGTGTGTAATGA
TACCACATGTGGTTTTAATTTGCATTTCCAATGGCTAATGATGTTGAGTATCTTTTTGTGTGCTAATTTGCCATCTATGTATCCTCTTCG
GTGAAATGTCTTCATGTCTTTTGTCTATTTTCTATTTAGGTCATTTGTTCTTTTTACTATTGAGTTTTGAGAGGTTTTTTATATATCCTA
GATAAAATTCCTCTGTTAGATATGTGGTTGCTTGAATTTTTAACATAACTTCTACCAAGGAAAAATAAGTAAAATTTCCAACCCTTGCAT
GGCCAGTCACTTACTTAATTCCTGTCCTTCAGTGTTCCATCTAGAGAATTAAGAGATATGATGTATAAAATAGACATCGAGGGCCATTAA
GAGAGTAAATACTTAAAAATACATGTTATGAAAGCAAAGCCAATAATCACTGTAGGAGTATGAGTTGCCTAAGGGCCAAAACTAATGTAA
ATAAGAGAAAGTGTGGATATAAATGACCATTGTTTATAAACAGTTATGAAAAATGCTGTGACTTGAAATCTTTCCCACATCTCCCAAGAA
AGTAGGTAGGAGTTTATCCTTTCCGTAATCTCTTTTTAACCCTGCTGACTATTACAGGGCTTGTTTAATCACAGTGGCAAGAATTACATG
TATCTTACAGTAAAGAAACAGAATACTGGAATCGTTAGAGAACCCTGATGTGTTGACCTGGATAAAGTACAAAGGTGGAAGAGGGAATGA
GTTATGCTGTTAAAATCTCAGGCTATTCTGTTAATGTTCCTGCTACTATGAACCCAAACTTTTTTTTTCCCCCTTTTGACTCCTTGTGTC
TTCCTCTCCTGTGGCATAAAAGTAGTTCTGTCGTTAACTTGTACAACATTGCCATCTGCTGTTGAGAATTGGTAGGTACTGCTTCTGAGA
ACCTGGCTGCAGATCCTTAGCATAGGCAGCAAATGTTGAGAAAGTCTATCTGTAGTATTACATATACTAAGTTACAGAGGATGCATCCAA
GTAGAGAAAATAATATGTGGGTTAAGATACATCCTTAAACTTTTTTTTTTTTGGGGGGGGGGGGACGGAGTCTTGCTGCAACGCCCAGGC
TGGAGTGCAATGGCACTATCTCAGCTCGCTGCAACCTTCACCTCCTGGGTTCAAGCAATTCTCCTGCCTCAGCCTCCTGAGTAGCTGGGA
ATATAGGTGCACACCACCATGCCTGGCTAATTTTTGTATTTTCAGTAGAAGCAGAGTTTCACCATATTGGCCAGGTTGGTCTCGAACTCC
TGACCTCAAGTGATCTGCCTGCCTCAGCCTCCCAAAGTGCTGGGATTACACGCGTGAGCCACCACACCCAGCCTCCATCTTTAAACTTTT
AAATGTGAAATTTCTATCATGTACCGTTAGCCTAACAAGATTTTCTTTCCTATTTCTGACTGGTGCCTTTCCCCTTTTTAGGAGCAACGA
AAGCTACTCTCTTAGTTATGTTCTTGTGATGTGACAAAATGTCAAGAAGATAGGAGAAGAGAATATTTTATTTCGTTGATGCTTTTGTTC
CCAAGTGTGACCCTAAACTTAAGCTTTGTAGGAGTTGACATTCTTTCATGTCCCTTCCCTTTACTCATGCCGAAACTATCAACTGGGACA
TTTTGTGCTTTTGGTTTAAAAGTTAATTGATATTATACTTTGGTTTTATCTAAAAAGTAAATGTATTTGCCTTTGACAAAAGACTGACAC
AAGAGCAAATAAGCTTTAAAATCGGGTGTTATGTGCTTTCCTCCATTTTTGAGCATATTATCCAAAATGGTCTGTATAATATAAATGAGA
ATGATGCAGTTTAAGTAAGCCTTGTTATACCATTGTCATGGACCCCTGTCATAAAGCCATTTCTTGGTTTGTTTGGGAAAGAGGCATATG
GGATTTATACAGATTCACTTGTAAATGTTGGATTGGGGATTTTTGTGTAAATTTTCTCAAATAAAGGCTAGCAGAAACCATTGCAAAAGT
TGAGAAGCTCAAACCATTAGAGGTAGAGCTGCGACGCCTAGAAGACCTTTCAGAATCTATTGTTAATGATTTTGCCTACATGAAGAAGAG
AGAAGAGGAGATGCGTGATACCAACGGAACAGGGCGGATACCTGACCAACTCGTGATCCTAGACATGAAGCATGGAGTGGAGGCGAAAAA
TTACGAAGAGATCACAGATTCTGCTGGCCATATTCTCTACTCCAAAGAGGATGCAACCAAGGGGAAATTTGCCTTTACCACTGAAGATTA

>88038_88038_6_SULF1-TMED10_SULF1_chr8_70517137_ENST00000402687_TMED10_chr14_75643112_ENST00000303575_length(amino acids)=464AA_BP=
MKYSCCALVLAVLGTELLGSLCSTVRSPRFRGRIQQERKNIRPNIILVLTDDQDVELGSLQVMNKTRKIMEHGGATFINAFVTTPMCCPS
RSSMLTGKYVHNHNVYTNNENCSSPSWQAMHEPRTFAVYLNNTGYRTAFFGKYLNEYNGSYIPPGWREWLGLIKNSRFYNYTVCRNGIKE
KHGFDYAKDYFTDLITNESINYFKMSKRMYPHRPVMMVISHAAPHGPEDSAPQFSKLYPNASQHITPSYNYAPNMDKHWIMQYTGPMLPI
HMEFTNILQRKRLQTLMSVDDSVERLYNMLVETGELENTYIIYTADHGYHIGQFGLVKGKSMPYDFDIRVPFFIRGPSVEPGSIVPQIVL
NIDLAPTILDIAGLDTPPDVDGKSVLKLLDPEKPGNRFRTNKKAKIWRDTFLVERGTRQPVNNRGRVNKHSGPILQHLFNVLSHWTSYLA

--------------------------------------------------------------
>88038_88038_7_SULF1-TMED10_SULF1_chr8_70517137_ENST00000419716_TMED10_chr14_75643112_ENST00000303575_length(transcript)=5743nt_BP=1838nt
GTGATGATAATAATACGCGGGCTTATATAACCGTCTTCATCTTGCGAGCACTTCGCAGACCGTCGCTAATGAATCTTGGGGCCGGTGTCG
GGCCGGGGCGGCTTGATCGGCAACTAGGAAACCCCAGGCGCAGAGGCCAGGAGCGAGGGCAGCGAGGATCAGAGGCCAGGCCTTCCCGGC
TGCCGGCGCTCCTCGGAGGTCAGGGCAGATGAGGAACATGACTCTCCCCCTTCGGAGGAGGAAGGAAGTCCCGCTGCCACCTTATCTCTG
CTCCTCTGCCTCCTCCCTGTTCCCAGAGCTTTTTCTCTAGAGAAGATTTTGAAGGCGGCTTTTGTGCTGACGGCCACCCACCATCATCTA
AAGAAGATAAACTTGGCAAATGACATGCAGGTTCTTCAAGGCAGAATAATTGCAGAAAATCTTCAAAGGACCCTATCTGCAGATGTTCTG
AATACCTCTGAGAATAGAGATTGATTATTCAACCAGGATACCTAATTCAAGAACTCCAGAAATCAGGAGACGGAGACATTTTGTCAGTTT
TGCAACATTGGACCAAATACAATGAAGTATTCTTGCTGTGCTCTGGTTTTGGCTGTCCTGGGCACAGAATTGCTGGGAAGCCTCTGTTCG
ACTGTCAGATCCCCGAGGTTCAGAGGACGGATACAGCAGGAACGAAAAAACATCCGACCCAACATTATTCTTGTGCTTACCGATGATCAA
GATGTGGAGCTGGGGTCCCTGCAAGTCATGAACAAAACGAGAAAGATTATGGAACATGGGGGGGCCACCTTCATCAATGCCTTTGTGACT
ACACCCATGTGCTGCCCGTCACGGTCCTCCATGCTCACCGGGAAGTATGTGCACAATCACAATGTCTACACCAACAACGAGAACTGCTCT
TCCCCCTCGTGGCAGGCCATGCATGAGCCTCGGACTTTTGCTGTATATCTTAACAACACTGGCTACAGAACAGCCTTTTTTGGAAAATAC
CTCAATGAATATAATGGCAGCTACATCCCCCCTGGGTGGCGAGAATGGCTTGGATTAATCAAGAATTCTCGCTTCTATAATTACACTGTT
TGTCGCAATGGCATCAAAGAAAAGCATGGATTTGATTATGCAAAGGACTACTTCACAGACTTAATCACTAACGAGAGCATTAATTACTTC
AAAATGTCTAAGAGAATGTATCCCCATAGGCCCGTTATGATGGTGATCAGCCACGCTGCGCCCCACGGCCCCGAGGACTCAGCCCCACAG
TTTTCTAAACTGTACCCCAATGCTTCCCAACACATAACTCCTAGTTATAACTATGCACCAAATATGGATAAACACTGGATTATGCAGTAC
ACAGGACCAATGCTGCCCATCCACATGGAATTTACAAACATTCTACAGCGCAAAAGGCTCCAGACTTTGATGTCAGTGGATGATTCTGTG
GAGAGGCTGTATAACATGCTCGTGGAGACGGGGGAGCTGGAGAATACTTACATCATTTACACCGCCGACCATGGTTACCATATTGGGCAG
TTTGGACTGGTCAAGGGGAAATCCATGCCATATGACTTTGATATTCGTGTGCCTTTTTTTATTCGTGGTCCAAGTGTAGAACCAGGATCA
ATAGTCCCACAGATCGTTCTCAACATTGACTTGGCCCCCACGATCCTGGATATTGCTGGGCTCGACACACCTCCTGATGTGGACGGCAAG
TCTGTCCTCAAACTTCTGGACCCAGAAAAGCCAGGTAACAGGTTTCGAACAAACAAGAAGGCCAAAATTTGGCGTGATACATTCCTAGTG
GAAAGAGGTACCAGACAGCCTGTGAACAACCGGGGCAGAGTCAACAAACACTCGGGTCCTATACTTCAGCATCTTTTCAATGTTCTGTCT
CATTGGACTAGCTACCTGGCAGGTCTTCTACCTGCGACGCTTCTTCAAGGCCAAGAAATTGATTGAGTAATGAATGAGGCATATTCTCCT
CCCACCTTGTACCTCAGCCAGCAGAACATCGCTGGGACGTGCCTGGCCTAAGGCATCCTACCAACAGCACCATCAAGGCACGTTGGAGCT
TTCTTGCCAGAACTGATCTCTTTTGGTGTGGGAGGACATGGGGTACCACCTACACCCAACAAGTCAATGAGGGACTTCTTTTTAATTTGG
TAGGATTTTGACTGGTTTTGCAACAATAGGTCTATTATTAGAGTCACCTATGACAAAAAATAGGGGTTACCTAGATAATGCCAAAGTCAG
CATTTGTCCTGGGTTCCCTTGTGTGATCTGTTTGGACTATGTTTTCTTTTCTTCTCCCACTTGCTCAGCAGCTTGGGCTTCCATTCTAGT
TCTTTTACCAAGATTTTTGTGTGACCATGTTGACTTCATTTGGATTGCCCTCTTTCAATTTCCTTGTGAAAACACCCTTAACTTTCTCTT
TACCCTTAGCTGAAATGTTTACATAGCTTCTGGTGATATCTTTTCATGATTTTATATCTCTTAAAATGGTGATGGATGTGACACCTCATA
AAAGTGAGCTTTGAACTGTAGATAACTCTTAAAGAAAATGTCATTTTAGACAATTAAAATATTTGTGCTCAACTGCTTGAACTTTTTTCG
TGTATGTGTATTTAATTCTATGCAATATTATCACATGTGTAGATTCATGTGACCACCATCACAAGAGACAGAACAGTTCTGTCACATGGA
TCCCTTGCACTGCCCTTTTACAGCCGCAGCCACATCCCTTTCTTATACCCTCACCCCAACCTGTGGCTACCACTGTTCTGTCCTCCATCT
CTGTAATTTTGTCATTTCAAGAATGTTGTATGAATGGAATCATACAGAATGTAATCTTACGAGGCTGATCTTTTTTCATTCAGCATAATT
CCCTTGAAATCCATCCAAGTTGTTGCATGTATGAATAGTTTCTTCCTTTTTTTCTTTTAAAAATGTTTTATATATTTAGGGGGTATAAGT
ACAGATTTCTTACATGCATATATTGCATCGTGGTGAAGTGGGGGCAGTTCCTTTTGATTGCTGAGTAGTATTCCATGGTATGGATGTACC
ACAGTTTGCTTAACCATTCACCCACTAAAGGACATAAGAGTTGTTTTCAGTTTTTTGCCCTAATAAAGCTGCTGTGAACATTCATGTACA
GGTTTTTATGTGAACATACATTTTCATTTTCTGGGATAAATGCTCAAAAGGGCAACTGTTGGGTTGTATGGTAAACACATATATTTTTGT
AAGAAACTACCCTACTCTTTTTCCAGAGTGGCTCTACTTTTTACATACAGCCACTCATACAATTCAGACAGCAATGTATGATTGATCCAG
TTTCTTCACATCCTCACCAGCATTTGGTATTACTACTATTTTTTATCTTAACCATTCACATAGATGTGTGTAATGATACCACATGTGGTT
TTAATTTGCATTTCCAATGGCTAATGATGTTGAGTATCTTTTTGTGTGCTAATTTGCCATCTATGTATCCTCTTCGGTGAAATGTCTTCA
TGTCTTTTGTCTATTTTCTATTTAGGTCATTTGTTCTTTTTACTATTGAGTTTTGAGAGGTTTTTTATATATCCTAGATAAAATTCCTCT
GTTAGATATGTGGTTGCTTGAATTTTTAACATAACTTCTACCAAGGAAAAATAAGTAAAATTTCCAACCCTTGCATGGCCAGTCACTTAC
TTAATTCCTGTCCTTCAGTGTTCCATCTAGAGAATTAAGAGATATGATGTATAAAATAGACATCGAGGGCCATTAAGAGAGTAAATACTT
AAAAATACATGTTATGAAAGCAAAGCCAATAATCACTGTAGGAGTATGAGTTGCCTAAGGGCCAAAACTAATGTAAATAAGAGAAAGTGT
GGATATAAATGACCATTGTTTATAAACAGTTATGAAAAATGCTGTGACTTGAAATCTTTCCCACATCTCCCAAGAAAGTAGGTAGGAGTT
TATCCTTTCCGTAATCTCTTTTTAACCCTGCTGACTATTACAGGGCTTGTTTAATCACAGTGGCAAGAATTACATGTATCTTACAGTAAA
GAAACAGAATACTGGAATCGTTAGAGAACCCTGATGTGTTGACCTGGATAAAGTACAAAGGTGGAAGAGGGAATGAGTTATGCTGTTAAA
ATCTCAGGCTATTCTGTTAATGTTCCTGCTACTATGAACCCAAACTTTTTTTTTCCCCCTTTTGACTCCTTGTGTCTTCCTCTCCTGTGG
CATAAAAGTAGTTCTGTCGTTAACTTGTACAACATTGCCATCTGCTGTTGAGAATTGGTAGGTACTGCTTCTGAGAACCTGGCTGCAGAT
CCTTAGCATAGGCAGCAAATGTTGAGAAAGTCTATCTGTAGTATTACATATACTAAGTTACAGAGGATGCATCCAAGTAGAGAAAATAAT
ATGTGGGTTAAGATACATCCTTAAACTTTTTTTTTTTTGGGGGGGGGGGGACGGAGTCTTGCTGCAACGCCCAGGCTGGAGTGCAATGGC
ACTATCTCAGCTCGCTGCAACCTTCACCTCCTGGGTTCAAGCAATTCTCCTGCCTCAGCCTCCTGAGTAGCTGGGAATATAGGTGCACAC
CACCATGCCTGGCTAATTTTTGTATTTTCAGTAGAAGCAGAGTTTCACCATATTGGCCAGGTTGGTCTCGAACTCCTGACCTCAAGTGAT
CTGCCTGCCTCAGCCTCCCAAAGTGCTGGGATTACACGCGTGAGCCACCACACCCAGCCTCCATCTTTAAACTTTTAAATGTGAAATTTC
TATCATGTACCGTTAGCCTAACAAGATTTTCTTTCCTATTTCTGACTGGTGCCTTTCCCCTTTTTAGGAGCAACGAAAGCTACTCTCTTA
GTTATGTTCTTGTGATGTGACAAAATGTCAAGAAGATAGGAGAAGAGAATATTTTATTTCGTTGATGCTTTTGTTCCCAAGTGTGACCCT
AAACTTAAGCTTTGTAGGAGTTGACATTCTTTCATGTCCCTTCCCTTTACTCATGCCGAAACTATCAACTGGGACATTTTGTGCTTTTGG
TTTAAAAGTTAATTGATATTATACTTTGGTTTTATCTAAAAAGTAAATGTATTTGCCTTTGACAAAAGACTGACACAAGAGCAAATAAGC
TTTAAAATCGGGTGTTATGTGCTTTCCTCCATTTTTGAGCATATTATCCAAAATGGTCTGTATAATATAAATGAGAATGATGCAGTTTAA
GTAAGCCTTGTTATACCATTGTCATGGACCCCTGTCATAAAGCCATTTCTTGGTTTGTTTGGGAAAGAGGCATATGGGATTTATACAGAT
TCACTTGTAAATGTTGGATTGGGGATTTTTGTGTAAATTTTCTCAAATAAAGGCTAGCAGAAACCATTGCAAAAGTTGAGAAGCTCAAAC
CATTAGAGGTAGAGCTGCGACGCCTAGAAGACCTTTCAGAATCTATTGTTAATGATTTTGCCTACATGAAGAAGAGAGAAGAGGAGATGC
GTGATACCAACGGAACAGGGCGGATACCTGACCAACTCGTGATCCTAGACATGAAGCATGGAGTGGAGGCGAAAAATTACGAAGAGATCA
CAGATTCTGCTGGCCATATTCTCTACTCCAAAGAGGATGCAACCAAGGGGAAATTTGCCTTTACCACTGAAGATTATGACATGTTTGAAG

>88038_88038_7_SULF1-TMED10_SULF1_chr8_70517137_ENST00000419716_TMED10_chr14_75643112_ENST00000303575_length(amino acids)=464AA_BP=
MKYSCCALVLAVLGTELLGSLCSTVRSPRFRGRIQQERKNIRPNIILVLTDDQDVELGSLQVMNKTRKIMEHGGATFINAFVTTPMCCPS
RSSMLTGKYVHNHNVYTNNENCSSPSWQAMHEPRTFAVYLNNTGYRTAFFGKYLNEYNGSYIPPGWREWLGLIKNSRFYNYTVCRNGIKE
KHGFDYAKDYFTDLITNESINYFKMSKRMYPHRPVMMVISHAAPHGPEDSAPQFSKLYPNASQHITPSYNYAPNMDKHWIMQYTGPMLPI
HMEFTNILQRKRLQTLMSVDDSVERLYNMLVETGELENTYIIYTADHGYHIGQFGLVKGKSMPYDFDIRVPFFIRGPSVEPGSIVPQIVL
NIDLAPTILDIAGLDTPPDVDGKSVLKLLDPEKPGNRFRTNKKAKIWRDTFLVERGTRQPVNNRGRVNKHSGPILQHLFNVLSHWTSYLA

--------------------------------------------------------------
>88038_88038_8_SULF1-TMED10_SULF1_chr8_70517137_ENST00000458141_TMED10_chr14_75643112_ENST00000303575_length(transcript)=5737nt_BP=1832nt
AGGTTACTTGACTGGGAGTTCTCAGACCTCCAGTTTCAGCCCTGCCCTCAGCCTCCAATCCGTAAGAGACACCCAGCCCCAGCAATTGGA
TTGGGCAGCCCGTCTTGACACACCACTGTGCTGAGTGCTTGAGGACGTGTTTCAACAGATGGTTGGGGTTAGTGTGTGTCATCACATTCG
AGTGGGGATTAAGAGAAGGAAGGCTGCCTTGCTGGAGCTGTGTGGTCTTCTCCAAGTGAGAGTCGCAGGCAATAGAACTACTTTGCTTTT
GGAGGAAAAGGAGGAATTCATTTTCAGCAGACACAAGAAAAGCAGTTTTTTTTTCAGGTGCTGACGGCCACCCACCATCATCTAAAGAAG
ATAAACTTGGCAAATGACATGCAGGTTCTTCAAGGCAGAATAATTGCAGAAAATCTTCAAAGGACCCTATCTGCAGATGTTCTGAATACC
TCTGAGAATAGAGATTGATTATTCAACCAGGATACCTAATTCAAGAACTCCAGAAATCAGGAGACGGAGACATTTTGTCAGTTTTGCAAC
ATTGGACCAAATACAATGAAGTATTCTTGCTGTGCTCTGGTTTTGGCTGTCCTGGGCACAGAATTGCTGGGAAGCCTCTGTTCGACTGTC
AGATCCCCGAGGTTCAGAGGACGGATACAGCAGGAACGAAAAAACATCCGACCCAACATTATTCTTGTGCTTACCGATGATCAAGATGTG
GAGCTGGGGTCCCTGCAAGTCATGAACAAAACGAGAAAGATTATGGAACATGGGGGGGCCACCTTCATCAATGCCTTTGTGACTACACCC
ATGTGCTGCCCGTCACGGTCCTCCATGCTCACCGGGAAGTATGTGCACAATCACAATGTCTACACCAACAACGAGAACTGCTCTTCCCCC
TCGTGGCAGGCCATGCATGAGCCTCGGACTTTTGCTGTATATCTTAACAACACTGGCTACAGAACAGCCTTTTTTGGAAAATACCTCAAT
GAATATAATGGCAGCTACATCCCCCCTGGGTGGCGAGAATGGCTTGGATTAATCAAGAATTCTCGCTTCTATAATTACACTGTTTGTCGC
AATGGCATCAAAGAAAAGCATGGATTTGATTATGCAAAGGACTACTTCACAGACTTAATCACTAACGAGAGCATTAATTACTTCAAAATG
TCTAAGAGAATGTATCCCCATAGGCCCGTTATGATGGTGATCAGCCACGCTGCGCCCCACGGCCCCGAGGACTCAGCCCCACAGTTTTCT
AAACTGTACCCCAATGCTTCCCAACACATAACTCCTAGTTATAACTATGCACCAAATATGGATAAACACTGGATTATGCAGTACACAGGA
CCAATGCTGCCCATCCACATGGAATTTACAAACATTCTACAGCGCAAAAGGCTCCAGACTTTGATGTCAGTGGATGATTCTGTGGAGAGG
CTGTATAACATGCTCGTGGAGACGGGGGAGCTGGAGAATACTTACATCATTTACACCGCCGACCATGGTTACCATATTGGGCAGTTTGGA
CTGGTCAAGGGGAAATCCATGCCATATGACTTTGATATTCGTGTGCCTTTTTTTATTCGTGGTCCAAGTGTAGAACCAGGATCAATAGTC
CCACAGATCGTTCTCAACATTGACTTGGCCCCCACGATCCTGGATATTGCTGGGCTCGACACACCTCCTGATGTGGACGGCAAGTCTGTC
CTCAAACTTCTGGACCCAGAAAAGCCAGGTAACAGGTTTCGAACAAACAAGAAGGCCAAAATTTGGCGTGATACATTCCTAGTGGAAAGA
GGTACCAGACAGCCTGTGAACAACCGGGGCAGAGTCAACAAACACTCGGGTCCTATACTTCAGCATCTTTTCAATGTTCTGTCTCATTGG
ACTAGCTACCTGGCAGGTCTTCTACCTGCGACGCTTCTTCAAGGCCAAGAAATTGATTGAGTAATGAATGAGGCATATTCTCCTCCCACC
TTGTACCTCAGCCAGCAGAACATCGCTGGGACGTGCCTGGCCTAAGGCATCCTACCAACAGCACCATCAAGGCACGTTGGAGCTTTCTTG
CCAGAACTGATCTCTTTTGGTGTGGGAGGACATGGGGTACCACCTACACCCAACAAGTCAATGAGGGACTTCTTTTTAATTTGGTAGGAT
TTTGACTGGTTTTGCAACAATAGGTCTATTATTAGAGTCACCTATGACAAAAAATAGGGGTTACCTAGATAATGCCAAAGTCAGCATTTG
TCCTGGGTTCCCTTGTGTGATCTGTTTGGACTATGTTTTCTTTTCTTCTCCCACTTGCTCAGCAGCTTGGGCTTCCATTCTAGTTCTTTT
ACCAAGATTTTTGTGTGACCATGTTGACTTCATTTGGATTGCCCTCTTTCAATTTCCTTGTGAAAACACCCTTAACTTTCTCTTTACCCT
TAGCTGAAATGTTTACATAGCTTCTGGTGATATCTTTTCATGATTTTATATCTCTTAAAATGGTGATGGATGTGACACCTCATAAAAGTG
AGCTTTGAACTGTAGATAACTCTTAAAGAAAATGTCATTTTAGACAATTAAAATATTTGTGCTCAACTGCTTGAACTTTTTTCGTGTATG
TGTATTTAATTCTATGCAATATTATCACATGTGTAGATTCATGTGACCACCATCACAAGAGACAGAACAGTTCTGTCACATGGATCCCTT
GCACTGCCCTTTTACAGCCGCAGCCACATCCCTTTCTTATACCCTCACCCCAACCTGTGGCTACCACTGTTCTGTCCTCCATCTCTGTAA
TTTTGTCATTTCAAGAATGTTGTATGAATGGAATCATACAGAATGTAATCTTACGAGGCTGATCTTTTTTCATTCAGCATAATTCCCTTG
AAATCCATCCAAGTTGTTGCATGTATGAATAGTTTCTTCCTTTTTTTCTTTTAAAAATGTTTTATATATTTAGGGGGTATAAGTACAGAT
TTCTTACATGCATATATTGCATCGTGGTGAAGTGGGGGCAGTTCCTTTTGATTGCTGAGTAGTATTCCATGGTATGGATGTACCACAGTT
TGCTTAACCATTCACCCACTAAAGGACATAAGAGTTGTTTTCAGTTTTTTGCCCTAATAAAGCTGCTGTGAACATTCATGTACAGGTTTT
TATGTGAACATACATTTTCATTTTCTGGGATAAATGCTCAAAAGGGCAACTGTTGGGTTGTATGGTAAACACATATATTTTTGTAAGAAA
CTACCCTACTCTTTTTCCAGAGTGGCTCTACTTTTTACATACAGCCACTCATACAATTCAGACAGCAATGTATGATTGATCCAGTTTCTT
CACATCCTCACCAGCATTTGGTATTACTACTATTTTTTATCTTAACCATTCACATAGATGTGTGTAATGATACCACATGTGGTTTTAATT
TGCATTTCCAATGGCTAATGATGTTGAGTATCTTTTTGTGTGCTAATTTGCCATCTATGTATCCTCTTCGGTGAAATGTCTTCATGTCTT
TTGTCTATTTTCTATTTAGGTCATTTGTTCTTTTTACTATTGAGTTTTGAGAGGTTTTTTATATATCCTAGATAAAATTCCTCTGTTAGA
TATGTGGTTGCTTGAATTTTTAACATAACTTCTACCAAGGAAAAATAAGTAAAATTTCCAACCCTTGCATGGCCAGTCACTTACTTAATT
CCTGTCCTTCAGTGTTCCATCTAGAGAATTAAGAGATATGATGTATAAAATAGACATCGAGGGCCATTAAGAGAGTAAATACTTAAAAAT
ACATGTTATGAAAGCAAAGCCAATAATCACTGTAGGAGTATGAGTTGCCTAAGGGCCAAAACTAATGTAAATAAGAGAAAGTGTGGATAT
AAATGACCATTGTTTATAAACAGTTATGAAAAATGCTGTGACTTGAAATCTTTCCCACATCTCCCAAGAAAGTAGGTAGGAGTTTATCCT
TTCCGTAATCTCTTTTTAACCCTGCTGACTATTACAGGGCTTGTTTAATCACAGTGGCAAGAATTACATGTATCTTACAGTAAAGAAACA
GAATACTGGAATCGTTAGAGAACCCTGATGTGTTGACCTGGATAAAGTACAAAGGTGGAAGAGGGAATGAGTTATGCTGTTAAAATCTCA
GGCTATTCTGTTAATGTTCCTGCTACTATGAACCCAAACTTTTTTTTTCCCCCTTTTGACTCCTTGTGTCTTCCTCTCCTGTGGCATAAA
AGTAGTTCTGTCGTTAACTTGTACAACATTGCCATCTGCTGTTGAGAATTGGTAGGTACTGCTTCTGAGAACCTGGCTGCAGATCCTTAG
CATAGGCAGCAAATGTTGAGAAAGTCTATCTGTAGTATTACATATACTAAGTTACAGAGGATGCATCCAAGTAGAGAAAATAATATGTGG
GTTAAGATACATCCTTAAACTTTTTTTTTTTTGGGGGGGGGGGGACGGAGTCTTGCTGCAACGCCCAGGCTGGAGTGCAATGGCACTATC
TCAGCTCGCTGCAACCTTCACCTCCTGGGTTCAAGCAATTCTCCTGCCTCAGCCTCCTGAGTAGCTGGGAATATAGGTGCACACCACCAT
GCCTGGCTAATTTTTGTATTTTCAGTAGAAGCAGAGTTTCACCATATTGGCCAGGTTGGTCTCGAACTCCTGACCTCAAGTGATCTGCCT
GCCTCAGCCTCCCAAAGTGCTGGGATTACACGCGTGAGCCACCACACCCAGCCTCCATCTTTAAACTTTTAAATGTGAAATTTCTATCAT
GTACCGTTAGCCTAACAAGATTTTCTTTCCTATTTCTGACTGGTGCCTTTCCCCTTTTTAGGAGCAACGAAAGCTACTCTCTTAGTTATG
TTCTTGTGATGTGACAAAATGTCAAGAAGATAGGAGAAGAGAATATTTTATTTCGTTGATGCTTTTGTTCCCAAGTGTGACCCTAAACTT
AAGCTTTGTAGGAGTTGACATTCTTTCATGTCCCTTCCCTTTACTCATGCCGAAACTATCAACTGGGACATTTTGTGCTTTTGGTTTAAA
AGTTAATTGATATTATACTTTGGTTTTATCTAAAAAGTAAATGTATTTGCCTTTGACAAAAGACTGACACAAGAGCAAATAAGCTTTAAA
ATCGGGTGTTATGTGCTTTCCTCCATTTTTGAGCATATTATCCAAAATGGTCTGTATAATATAAATGAGAATGATGCAGTTTAAGTAAGC
CTTGTTATACCATTGTCATGGACCCCTGTCATAAAGCCATTTCTTGGTTTGTTTGGGAAAGAGGCATATGGGATTTATACAGATTCACTT
GTAAATGTTGGATTGGGGATTTTTGTGTAAATTTTCTCAAATAAAGGCTAGCAGAAACCATTGCAAAAGTTGAGAAGCTCAAACCATTAG
AGGTAGAGCTGCGACGCCTAGAAGACCTTTCAGAATCTATTGTTAATGATTTTGCCTACATGAAGAAGAGAGAAGAGGAGATGCGTGATA
CCAACGGAACAGGGCGGATACCTGACCAACTCGTGATCCTAGACATGAAGCATGGAGTGGAGGCGAAAAATTACGAAGAGATCACAGATT
CTGCTGGCCATATTCTCTACTCCAAAGAGGATGCAACCAAGGGGAAATTTGCCTTTACCACTGAAGATTATGACATGTTTGAAGTGTGTT

>88038_88038_8_SULF1-TMED10_SULF1_chr8_70517137_ENST00000458141_TMED10_chr14_75643112_ENST00000303575_length(amino acids)=464AA_BP=
MKYSCCALVLAVLGTELLGSLCSTVRSPRFRGRIQQERKNIRPNIILVLTDDQDVELGSLQVMNKTRKIMEHGGATFINAFVTTPMCCPS
RSSMLTGKYVHNHNVYTNNENCSSPSWQAMHEPRTFAVYLNNTGYRTAFFGKYLNEYNGSYIPPGWREWLGLIKNSRFYNYTVCRNGIKE
KHGFDYAKDYFTDLITNESINYFKMSKRMYPHRPVMMVISHAAPHGPEDSAPQFSKLYPNASQHITPSYNYAPNMDKHWIMQYTGPMLPI
HMEFTNILQRKRLQTLMSVDDSVERLYNMLVETGELENTYIIYTADHGYHIGQFGLVKGKSMPYDFDIRVPFFIRGPSVEPGSIVPQIVL
NIDLAPTILDIAGLDTPPDVDGKSVLKLLDPEKPGNRFRTNKKAKIWRDTFLVERGTRQPVNNRGRVNKHSGPILQHLFNVLSHWTSYLA

--------------------------------------------------------------

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Fusion Gene PPI Analysis for SULF1-TMED10


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with
TgeneTMED10chr8:70517136chr14:75643109ENST0000030357505207_2190220.0ARF1 and IL1B
TgeneTMED10chr8:70517137chr14:75643112ENST0000030357505207_2190220.0ARF1 and IL1B
TgeneTMED10chr8:70517136chr14:75643109ENST0000030357505204_2190220.0COPG1
TgeneTMED10chr8:70517137chr14:75643112ENST0000030357505204_2190220.0COPG1


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for SULF1-TMED10


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for SULF1-TMED10


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource