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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Diseases

Fusion gene:SUPT5H-CALR3 (FusionGDB2 ID:88149)

Fusion Gene Summary for SUPT5H-CALR3

check button Fusion gene summary
Fusion gene informationFusion gene name: SUPT5H-CALR3
Fusion gene ID: 88149
HgeneTgene
Gene symbol

SUPT5H

CALR3

Gene ID

6829

125972

Gene nameSPT5 homolog, DSIF elongation factor subunitcalreticulin 3
SynonymsSPT5|SPT5H|Tat-CT1CMH19|CRT2|CT93
Cytomap

19q13.2

19p13.11

Type of geneprotein-codingprotein-coding
Descriptiontranscription elongation factor SPT5DRB sensitivity-inducing factor 160 kDa subunitDRB sensitivity-inducing factor large subunitDSIF large subunitDSIF p160Tat-cotransactivator 1 proteinhSPT5suppressor of Ty 5 homologcalreticulin-3calreticulin-2calsperincancer/testis antigen 93testis secretory sperm-binding protein Li 226n
Modification date2020031320200313
UniProtAcc.

Q96L12

Ensembl transtripts involved in fusion geneENST00000359191, ENST00000402194, 
ENST00000432763, ENST00000598725, 
ENST00000599117, 		ENST00000602234, 
ENST00000269881, 
Fusion gene scores* DoF score17 X 13 X 9=19893 X 6 X 5=90
# samples 199
** MAII scorelog2(19/1989*10)=-3.3879719525028
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(9/90*10)=0
Context

PubMed: SUPT5H [Title/Abstract] AND CALR3 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointSUPT5H(39936605)-CALR3(16601381), # samples:3
Anticipated loss of major functional domain due to fusion event.SUPT5H-CALR3 seems lost the major protein functional domain in Hgene partner, which is a essential gene due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneSUPT5H

GO:0000122

negative regulation of transcription by RNA polymerase II

9450929

HgeneSUPT5H

GO:0006368

transcription elongation from RNA polymerase II promoter

9450929

HgeneSUPT5H

GO:0032785

negative regulation of DNA-templated transcription, elongation

9450929

HgeneSUPT5H

GO:0032786

positive regulation of DNA-templated transcription, elongation

9450929

HgeneSUPT5H

GO:0045944

positive regulation of transcription by RNA polymerase II

9450929


check buttonFusion gene breakpoints across SUPT5H (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across CALR3 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4OVTCGA-13-1410-01ASUPT5Hchr19

39936605

+CALR3chr19

16594926

-
ChimerDB4OVTCGA-13-1410-01ASUPT5Hchr19

39936605

+CALR3chr19

16601381

-
ChimerDB4OVTCGA-13-1410SUPT5Hchr19

39936605

+CALR3chr19

16594926

-
ChimerDB4OVTCGA-13-1410SUPT5Hchr19

39936605

+CALR3chr19

16601381

-


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Fusion Gene ORF analysis for SUPT5H-CALR3

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000359191ENST00000602234SUPT5Hchr19

39936605

+CALR3chr19

16601381

-
5CDS-intronENST00000402194ENST00000602234SUPT5Hchr19

39936605

+CALR3chr19

16601381

-
5CDS-intronENST00000432763ENST00000602234SUPT5Hchr19

39936605

+CALR3chr19

16601381

-
5CDS-intronENST00000598725ENST00000602234SUPT5Hchr19

39936605

+CALR3chr19

16601381

-
5CDS-intronENST00000599117ENST00000602234SUPT5Hchr19

39936605

+CALR3chr19

16601381

-
Frame-shiftENST00000359191ENST00000269881SUPT5Hchr19

39936605

+CALR3chr19

16601381

-
Frame-shiftENST00000402194ENST00000269881SUPT5Hchr19

39936605

+CALR3chr19

16601381

-
Frame-shiftENST00000432763ENST00000269881SUPT5Hchr19

39936605

+CALR3chr19

16601381

-
Frame-shiftENST00000598725ENST00000269881SUPT5Hchr19

39936605

+CALR3chr19

16601381

-
Frame-shiftENST00000599117ENST00000269881SUPT5Hchr19

39936605

+CALR3chr19

16601381

-
In-frameENST00000359191ENST00000269881SUPT5Hchr19

39936605

+CALR3chr19

16594926

-
In-frameENST00000359191ENST00000602234SUPT5Hchr19

39936605

+CALR3chr19

16594926

-
In-frameENST00000402194ENST00000269881SUPT5Hchr19

39936605

+CALR3chr19

16594926

-
In-frameENST00000402194ENST00000602234SUPT5Hchr19

39936605

+CALR3chr19

16594926

-
In-frameENST00000432763ENST00000269881SUPT5Hchr19

39936605

+CALR3chr19

16594926

-
In-frameENST00000432763ENST00000602234SUPT5Hchr19

39936605

+CALR3chr19

16594926

-
In-frameENST00000598725ENST00000269881SUPT5Hchr19

39936605

+CALR3chr19

16594926

-
In-frameENST00000598725ENST00000602234SUPT5Hchr19

39936605

+CALR3chr19

16594926

-
In-frameENST00000599117ENST00000269881SUPT5Hchr19

39936605

+CALR3chr19

16594926

-
In-frameENST00000599117ENST00000602234SUPT5Hchr19

39936605

+CALR3chr19

16594926

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000599117SUPT5Hchr1939936605+ENST00000269881CALR3chr1916594926-11794421361104322
ENST00000599117SUPT5Hchr1939936605+ENST00000602234CALR3chr1916594926-1030442248631127
ENST00000432763SUPT5Hchr1939936605+ENST00000269881CALR3chr1916594926-991254179916245
ENST00000432763SUPT5Hchr1939936605+ENST00000602234CALR3chr1916594926-84225460443127
ENST00000402194SUPT5Hchr1939936605+ENST00000269881CALR3chr1916594926-991254179916245
ENST00000402194SUPT5Hchr1939936605+ENST00000602234CALR3chr1916594926-84225460443127
ENST00000359191SUPT5Hchr1939936605+ENST00000269881CALR3chr1916594926-1059322247984245
ENST00000359191SUPT5Hchr1939936605+ENST00000602234CALR3chr1916594926-910322110511133
ENST00000598725SUPT5Hchr1939936605+ENST00000269881CALR3chr1916594926-1019282207944245
ENST00000598725SUPT5Hchr1939936605+ENST00000602234CALR3chr1916594926-87028270471133

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000599117ENST00000269881SUPT5Hchr1939936605+CALR3chr1916594926-0.0032594670.9967405
ENST00000599117ENST00000602234SUPT5Hchr1939936605+CALR3chr1916594926-0.294416160.7055838
ENST00000432763ENST00000269881SUPT5Hchr1939936605+CALR3chr1916594926-0.0029466660.9970534
ENST00000432763ENST00000602234SUPT5Hchr1939936605+CALR3chr1916594926-0.260704430.7392956
ENST00000402194ENST00000269881SUPT5Hchr1939936605+CALR3chr1916594926-0.0029466660.9970534
ENST00000402194ENST00000602234SUPT5Hchr1939936605+CALR3chr1916594926-0.260704430.7392956
ENST00000359191ENST00000269881SUPT5Hchr1939936605+CALR3chr1916594926-0.0025287460.99747133
ENST00000359191ENST00000602234SUPT5Hchr1939936605+CALR3chr1916594926-0.320888520.6791115
ENST00000598725ENST00000269881SUPT5Hchr1939936605+CALR3chr1916594926-0.002497650.9975024
ENST00000598725ENST00000602234SUPT5Hchr1939936605+CALR3chr1916594926-0.320111780.6798882

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Fusion Genomic Features for SUPT5H-CALR3


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for SUPT5H-CALR3


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr19:39936605/chr19:16601381)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
.CALR3

Q96L12

FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: During spermatogenesis, may act as a lectin-independent chaperone for specific client proteins such as ADAM3. Required for sperm fertility (By similarity). CALR3 capacity for calcium-binding may be absent or much lower than that of CALR. {ECO:0000250, ECO:0000269|PubMed:21590275}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneCALR3chr19:39936605chr19:16594926ENST0000026988139337_362164385.0Compositional biasNote=Glu/Lys-rich
TgeneCALR3chr19:39936605chr19:16594926ENST0000026988139381_384164385.0MotifPrevents secretion from ER
TgeneCALR3chr19:39936605chr19:16594926ENST0000026988139191_245164385.0RegionNote=4 X approximate repeats
TgeneCALR3chr19:39936605chr19:16594926ENST0000026988139198_294164385.0RegionNote=P-domain
TgeneCALR3chr19:39936605chr19:16594926ENST0000026988139249_283164385.0RegionNote=3 X approximate repeats
TgeneCALR3chr19:39936605chr19:16594926ENST0000026988139295_384164385.0RegionNote=C-domain
TgeneCALR3chr19:39936605chr19:16594926ENST0000026988139191_202164385.0RepeatNote=1-1
TgeneCALR3chr19:39936605chr19:16594926ENST0000026988139208_219164385.0RepeatNote=1-2
TgeneCALR3chr19:39936605chr19:16594926ENST0000026988139221_230164385.0RepeatNote=1-3
TgeneCALR3chr19:39936605chr19:16594926ENST0000026988139234_245164385.0RepeatNote=1-4
TgeneCALR3chr19:39936605chr19:16594926ENST0000026988139249_259164385.0RepeatNote=2-1
TgeneCALR3chr19:39936605chr19:16594926ENST0000026988139263_271164385.0RepeatNote=2-2
TgeneCALR3chr19:39936605chr19:16594926ENST0000026988139273_283164385.0RepeatNote=2-3

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneSUPT5Hchr19:39936605chr19:16594926ENST00000359191+12811_106251084.0Compositional biasNote=Glu-rich
HgeneSUPT5Hchr19:39936605chr19:16594926ENST00000359191+128844_968251084.0Compositional biasNote=Pro-rich
HgeneSUPT5Hchr19:39936605chr19:16594926ENST00000402194+22911_106251084.0Compositional biasNote=Glu-rich
HgeneSUPT5Hchr19:39936605chr19:16594926ENST00000402194+229844_968251084.0Compositional biasNote=Pro-rich
HgeneSUPT5Hchr19:39936605chr19:16594926ENST00000432763+23011_106251088.0Compositional biasNote=Glu-rich
HgeneSUPT5Hchr19:39936605chr19:16594926ENST00000432763+230844_968251088.0Compositional biasNote=Pro-rich
HgeneSUPT5Hchr19:39936605chr19:16594926ENST00000598725+12911_106251088.0Compositional biasNote=Glu-rich
HgeneSUPT5Hchr19:39936605chr19:16594926ENST00000598725+129844_968251088.0Compositional biasNote=Pro-rich
HgeneSUPT5Hchr19:39936605chr19:16594926ENST00000599117+33111_106251088.0Compositional biasNote=Glu-rich
HgeneSUPT5Hchr19:39936605chr19:16594926ENST00000599117+331844_968251088.0Compositional biasNote=Pro-rich
HgeneSUPT5Hchr19:39936605chr19:16594926ENST00000359191+128273_306251084.0DomainNote=KOW 1
HgeneSUPT5Hchr19:39936605chr19:16594926ENST00000359191+128420_451251084.0DomainNote=KOW 2
HgeneSUPT5Hchr19:39936605chr19:16594926ENST00000359191+128472_503251084.0DomainNote=KOW 3
HgeneSUPT5Hchr19:39936605chr19:16594926ENST00000359191+128594_627251084.0DomainNote=KOW 4
HgeneSUPT5Hchr19:39936605chr19:16594926ENST00000359191+128704_737251084.0DomainNote=KOW 5
HgeneSUPT5Hchr19:39936605chr19:16594926ENST00000402194+229273_306251084.0DomainNote=KOW 1
HgeneSUPT5Hchr19:39936605chr19:16594926ENST00000402194+229420_451251084.0DomainNote=KOW 2
HgeneSUPT5Hchr19:39936605chr19:16594926ENST00000402194+229472_503251084.0DomainNote=KOW 3
HgeneSUPT5Hchr19:39936605chr19:16594926ENST00000402194+229594_627251084.0DomainNote=KOW 4
HgeneSUPT5Hchr19:39936605chr19:16594926ENST00000402194+229704_737251084.0DomainNote=KOW 5
HgeneSUPT5Hchr19:39936605chr19:16594926ENST00000432763+230273_306251088.0DomainNote=KOW 1
HgeneSUPT5Hchr19:39936605chr19:16594926ENST00000432763+230420_451251088.0DomainNote=KOW 2
HgeneSUPT5Hchr19:39936605chr19:16594926ENST00000432763+230472_503251088.0DomainNote=KOW 3
HgeneSUPT5Hchr19:39936605chr19:16594926ENST00000432763+230594_627251088.0DomainNote=KOW 4
HgeneSUPT5Hchr19:39936605chr19:16594926ENST00000432763+230704_737251088.0DomainNote=KOW 5
HgeneSUPT5Hchr19:39936605chr19:16594926ENST00000598725+129273_306251088.0DomainNote=KOW 1
HgeneSUPT5Hchr19:39936605chr19:16594926ENST00000598725+129420_451251088.0DomainNote=KOW 2
HgeneSUPT5Hchr19:39936605chr19:16594926ENST00000598725+129472_503251088.0DomainNote=KOW 3
HgeneSUPT5Hchr19:39936605chr19:16594926ENST00000598725+129594_627251088.0DomainNote=KOW 4
HgeneSUPT5Hchr19:39936605chr19:16594926ENST00000598725+129704_737251088.0DomainNote=KOW 5
HgeneSUPT5Hchr19:39936605chr19:16594926ENST00000599117+331273_306251088.0DomainNote=KOW 1
HgeneSUPT5Hchr19:39936605chr19:16594926ENST00000599117+331420_451251088.0DomainNote=KOW 2
HgeneSUPT5Hchr19:39936605chr19:16594926ENST00000599117+331472_503251088.0DomainNote=KOW 3
HgeneSUPT5Hchr19:39936605chr19:16594926ENST00000599117+331594_627251088.0DomainNote=KOW 4
HgeneSUPT5Hchr19:39936605chr19:16594926ENST00000599117+331704_737251088.0DomainNote=KOW 5
HgeneSUPT5Hchr19:39936605chr19:16594926ENST00000359191+128754_817251084.0RegionNote=9 X 7 AA approximate tandem repeats of G-S-[QR]-T-P-X-[YQ]%2C motif CTR1
HgeneSUPT5Hchr19:39936605chr19:16594926ENST00000359191+128844_950251084.0RegionNote=10 X 8 AA approximate tandem repeats of P-[TS]-P-S-P-[QA]-[SG]-Y%2C motif CTR2
HgeneSUPT5Hchr19:39936605chr19:16594926ENST00000402194+229754_817251084.0RegionNote=9 X 7 AA approximate tandem repeats of G-S-[QR]-T-P-X-[YQ]%2C motif CTR1
HgeneSUPT5Hchr19:39936605chr19:16594926ENST00000402194+229844_950251084.0RegionNote=10 X 8 AA approximate tandem repeats of P-[TS]-P-S-P-[QA]-[SG]-Y%2C motif CTR2
HgeneSUPT5Hchr19:39936605chr19:16594926ENST00000432763+230754_817251088.0RegionNote=9 X 7 AA approximate tandem repeats of G-S-[QR]-T-P-X-[YQ]%2C motif CTR1
HgeneSUPT5Hchr19:39936605chr19:16594926ENST00000432763+230844_950251088.0RegionNote=10 X 8 AA approximate tandem repeats of P-[TS]-P-S-P-[QA]-[SG]-Y%2C motif CTR2
HgeneSUPT5Hchr19:39936605chr19:16594926ENST00000598725+129754_817251088.0RegionNote=9 X 7 AA approximate tandem repeats of G-S-[QR]-T-P-X-[YQ]%2C motif CTR1
HgeneSUPT5Hchr19:39936605chr19:16594926ENST00000598725+129844_950251088.0RegionNote=10 X 8 AA approximate tandem repeats of P-[TS]-P-S-P-[QA]-[SG]-Y%2C motif CTR2
HgeneSUPT5Hchr19:39936605chr19:16594926ENST00000599117+331754_817251088.0RegionNote=9 X 7 AA approximate tandem repeats of G-S-[QR]-T-P-X-[YQ]%2C motif CTR1
HgeneSUPT5Hchr19:39936605chr19:16594926ENST00000599117+331844_950251088.0RegionNote=10 X 8 AA approximate tandem repeats of P-[TS]-P-S-P-[QA]-[SG]-Y%2C motif CTR2
HgeneSUPT5Hchr19:39936605chr19:16594926ENST00000359191+128754_759251084.0RepeatNote=CTR1-1%3B approximate
HgeneSUPT5Hchr19:39936605chr19:16594926ENST00000359191+128760_765251084.0RepeatNote=CTR1-2
HgeneSUPT5Hchr19:39936605chr19:16594926ENST00000359191+128766_771251084.0RepeatNote=CTR1-3
HgeneSUPT5Hchr19:39936605chr19:16594926ENST00000359191+128772_778251084.0RepeatNote=CTR1-4
HgeneSUPT5Hchr19:39936605chr19:16594926ENST00000359191+128781_787251084.0RepeatNote=CTR1-5
HgeneSUPT5Hchr19:39936605chr19:16594926ENST00000359191+128788_794251084.0RepeatNote=CTR1-6
HgeneSUPT5Hchr19:39936605chr19:16594926ENST00000359191+128796_802251084.0RepeatNote=CTR1-7
HgeneSUPT5Hchr19:39936605chr19:16594926ENST00000359191+128803_809251084.0RepeatNote=CTR1-8
HgeneSUPT5Hchr19:39936605chr19:16594926ENST00000359191+128811_817251084.0RepeatNote=CTR1-9
HgeneSUPT5Hchr19:39936605chr19:16594926ENST00000359191+128844_851251084.0RepeatNote=CTR2-1
HgeneSUPT5Hchr19:39936605chr19:16594926ENST00000359191+128854_862251084.0RepeatNote=CTR2-2%3B approximate
HgeneSUPT5Hchr19:39936605chr19:16594926ENST00000359191+128863_869251084.0RepeatNote=CTR2-3%3B approximate
HgeneSUPT5Hchr19:39936605chr19:16594926ENST00000359191+128881_885251084.0RepeatNote=CTR2-4%3B half-length
HgeneSUPT5Hchr19:39936605chr19:16594926ENST00000359191+128896_902251084.0RepeatNote=CTR2-5%3B approximate
HgeneSUPT5Hchr19:39936605chr19:16594926ENST00000359191+128904_911251084.0RepeatNote=CTR2-6
HgeneSUPT5Hchr19:39936605chr19:16594926ENST00000359191+128916_921251084.0RepeatNote=CTR2-7%3B approximate
HgeneSUPT5Hchr19:39936605chr19:16594926ENST00000359191+128924_930251084.0RepeatNote=CTR2-8
HgeneSUPT5Hchr19:39936605chr19:16594926ENST00000359191+128932_939251084.0RepeatNote=CTR2-9
HgeneSUPT5Hchr19:39936605chr19:16594926ENST00000359191+128943_950251084.0RepeatNote=CTR2-10
HgeneSUPT5Hchr19:39936605chr19:16594926ENST00000402194+229754_759251084.0RepeatNote=CTR1-1%3B approximate
HgeneSUPT5Hchr19:39936605chr19:16594926ENST00000402194+229760_765251084.0RepeatNote=CTR1-2
HgeneSUPT5Hchr19:39936605chr19:16594926ENST00000402194+229766_771251084.0RepeatNote=CTR1-3
HgeneSUPT5Hchr19:39936605chr19:16594926ENST00000402194+229772_778251084.0RepeatNote=CTR1-4
HgeneSUPT5Hchr19:39936605chr19:16594926ENST00000402194+229781_787251084.0RepeatNote=CTR1-5
HgeneSUPT5Hchr19:39936605chr19:16594926ENST00000402194+229788_794251084.0RepeatNote=CTR1-6
HgeneSUPT5Hchr19:39936605chr19:16594926ENST00000402194+229796_802251084.0RepeatNote=CTR1-7
HgeneSUPT5Hchr19:39936605chr19:16594926ENST00000402194+229803_809251084.0RepeatNote=CTR1-8
HgeneSUPT5Hchr19:39936605chr19:16594926ENST00000402194+229811_817251084.0RepeatNote=CTR1-9
HgeneSUPT5Hchr19:39936605chr19:16594926ENST00000402194+229844_851251084.0RepeatNote=CTR2-1
HgeneSUPT5Hchr19:39936605chr19:16594926ENST00000402194+229854_862251084.0RepeatNote=CTR2-2%3B approximate
HgeneSUPT5Hchr19:39936605chr19:16594926ENST00000402194+229863_869251084.0RepeatNote=CTR2-3%3B approximate
HgeneSUPT5Hchr19:39936605chr19:16594926ENST00000402194+229881_885251084.0RepeatNote=CTR2-4%3B half-length
HgeneSUPT5Hchr19:39936605chr19:16594926ENST00000402194+229896_902251084.0RepeatNote=CTR2-5%3B approximate
HgeneSUPT5Hchr19:39936605chr19:16594926ENST00000402194+229904_911251084.0RepeatNote=CTR2-6
HgeneSUPT5Hchr19:39936605chr19:16594926ENST00000402194+229916_921251084.0RepeatNote=CTR2-7%3B approximate
HgeneSUPT5Hchr19:39936605chr19:16594926ENST00000402194+229924_930251084.0RepeatNote=CTR2-8
HgeneSUPT5Hchr19:39936605chr19:16594926ENST00000402194+229932_939251084.0RepeatNote=CTR2-9
HgeneSUPT5Hchr19:39936605chr19:16594926ENST00000402194+229943_950251084.0RepeatNote=CTR2-10
HgeneSUPT5Hchr19:39936605chr19:16594926ENST00000432763+230754_759251088.0RepeatNote=CTR1-1%3B approximate
HgeneSUPT5Hchr19:39936605chr19:16594926ENST00000432763+230760_765251088.0RepeatNote=CTR1-2
HgeneSUPT5Hchr19:39936605chr19:16594926ENST00000432763+230766_771251088.0RepeatNote=CTR1-3
HgeneSUPT5Hchr19:39936605chr19:16594926ENST00000432763+230772_778251088.0RepeatNote=CTR1-4
HgeneSUPT5Hchr19:39936605chr19:16594926ENST00000432763+230781_787251088.0RepeatNote=CTR1-5
HgeneSUPT5Hchr19:39936605chr19:16594926ENST00000432763+230788_794251088.0RepeatNote=CTR1-6
HgeneSUPT5Hchr19:39936605chr19:16594926ENST00000432763+230796_802251088.0RepeatNote=CTR1-7
HgeneSUPT5Hchr19:39936605chr19:16594926ENST00000432763+230803_809251088.0RepeatNote=CTR1-8
HgeneSUPT5Hchr19:39936605chr19:16594926ENST00000432763+230811_817251088.0RepeatNote=CTR1-9
HgeneSUPT5Hchr19:39936605chr19:16594926ENST00000432763+230844_851251088.0RepeatNote=CTR2-1
HgeneSUPT5Hchr19:39936605chr19:16594926ENST00000432763+230854_862251088.0RepeatNote=CTR2-2%3B approximate
HgeneSUPT5Hchr19:39936605chr19:16594926ENST00000432763+230863_869251088.0RepeatNote=CTR2-3%3B approximate
HgeneSUPT5Hchr19:39936605chr19:16594926ENST00000432763+230881_885251088.0RepeatNote=CTR2-4%3B half-length
HgeneSUPT5Hchr19:39936605chr19:16594926ENST00000432763+230896_902251088.0RepeatNote=CTR2-5%3B approximate
HgeneSUPT5Hchr19:39936605chr19:16594926ENST00000432763+230904_911251088.0RepeatNote=CTR2-6
HgeneSUPT5Hchr19:39936605chr19:16594926ENST00000432763+230916_921251088.0RepeatNote=CTR2-7%3B approximate
HgeneSUPT5Hchr19:39936605chr19:16594926ENST00000432763+230924_930251088.0RepeatNote=CTR2-8
HgeneSUPT5Hchr19:39936605chr19:16594926ENST00000432763+230932_939251088.0RepeatNote=CTR2-9
HgeneSUPT5Hchr19:39936605chr19:16594926ENST00000432763+230943_950251088.0RepeatNote=CTR2-10
HgeneSUPT5Hchr19:39936605chr19:16594926ENST00000598725+129754_759251088.0RepeatNote=CTR1-1%3B approximate
HgeneSUPT5Hchr19:39936605chr19:16594926ENST00000598725+129760_765251088.0RepeatNote=CTR1-2
HgeneSUPT5Hchr19:39936605chr19:16594926ENST00000598725+129766_771251088.0RepeatNote=CTR1-3
HgeneSUPT5Hchr19:39936605chr19:16594926ENST00000598725+129772_778251088.0RepeatNote=CTR1-4
HgeneSUPT5Hchr19:39936605chr19:16594926ENST00000598725+129781_787251088.0RepeatNote=CTR1-5
HgeneSUPT5Hchr19:39936605chr19:16594926ENST00000598725+129788_794251088.0RepeatNote=CTR1-6
HgeneSUPT5Hchr19:39936605chr19:16594926ENST00000598725+129796_802251088.0RepeatNote=CTR1-7
HgeneSUPT5Hchr19:39936605chr19:16594926ENST00000598725+129803_809251088.0RepeatNote=CTR1-8
HgeneSUPT5Hchr19:39936605chr19:16594926ENST00000598725+129811_817251088.0RepeatNote=CTR1-9
HgeneSUPT5Hchr19:39936605chr19:16594926ENST00000598725+129844_851251088.0RepeatNote=CTR2-1
HgeneSUPT5Hchr19:39936605chr19:16594926ENST00000598725+129854_862251088.0RepeatNote=CTR2-2%3B approximate
HgeneSUPT5Hchr19:39936605chr19:16594926ENST00000598725+129863_869251088.0RepeatNote=CTR2-3%3B approximate
HgeneSUPT5Hchr19:39936605chr19:16594926ENST00000598725+129881_885251088.0RepeatNote=CTR2-4%3B half-length
HgeneSUPT5Hchr19:39936605chr19:16594926ENST00000598725+129896_902251088.0RepeatNote=CTR2-5%3B approximate
HgeneSUPT5Hchr19:39936605chr19:16594926ENST00000598725+129904_911251088.0RepeatNote=CTR2-6
HgeneSUPT5Hchr19:39936605chr19:16594926ENST00000598725+129916_921251088.0RepeatNote=CTR2-7%3B approximate
HgeneSUPT5Hchr19:39936605chr19:16594926ENST00000598725+129924_930251088.0RepeatNote=CTR2-8
HgeneSUPT5Hchr19:39936605chr19:16594926ENST00000598725+129932_939251088.0RepeatNote=CTR2-9
HgeneSUPT5Hchr19:39936605chr19:16594926ENST00000598725+129943_950251088.0RepeatNote=CTR2-10
HgeneSUPT5Hchr19:39936605chr19:16594926ENST00000599117+331754_759251088.0RepeatNote=CTR1-1%3B approximate
HgeneSUPT5Hchr19:39936605chr19:16594926ENST00000599117+331760_765251088.0RepeatNote=CTR1-2
HgeneSUPT5Hchr19:39936605chr19:16594926ENST00000599117+331766_771251088.0RepeatNote=CTR1-3
HgeneSUPT5Hchr19:39936605chr19:16594926ENST00000599117+331772_778251088.0RepeatNote=CTR1-4
HgeneSUPT5Hchr19:39936605chr19:16594926ENST00000599117+331781_787251088.0RepeatNote=CTR1-5
HgeneSUPT5Hchr19:39936605chr19:16594926ENST00000599117+331788_794251088.0RepeatNote=CTR1-6
HgeneSUPT5Hchr19:39936605chr19:16594926ENST00000599117+331796_802251088.0RepeatNote=CTR1-7
HgeneSUPT5Hchr19:39936605chr19:16594926ENST00000599117+331803_809251088.0RepeatNote=CTR1-8
HgeneSUPT5Hchr19:39936605chr19:16594926ENST00000599117+331811_817251088.0RepeatNote=CTR1-9
HgeneSUPT5Hchr19:39936605chr19:16594926ENST00000599117+331844_851251088.0RepeatNote=CTR2-1
HgeneSUPT5Hchr19:39936605chr19:16594926ENST00000599117+331854_862251088.0RepeatNote=CTR2-2%3B approximate
HgeneSUPT5Hchr19:39936605chr19:16594926ENST00000599117+331863_869251088.0RepeatNote=CTR2-3%3B approximate
HgeneSUPT5Hchr19:39936605chr19:16594926ENST00000599117+331881_885251088.0RepeatNote=CTR2-4%3B half-length
HgeneSUPT5Hchr19:39936605chr19:16594926ENST00000599117+331896_902251088.0RepeatNote=CTR2-5%3B approximate
HgeneSUPT5Hchr19:39936605chr19:16594926ENST00000599117+331904_911251088.0RepeatNote=CTR2-6
HgeneSUPT5Hchr19:39936605chr19:16594926ENST00000599117+331916_921251088.0RepeatNote=CTR2-7%3B approximate
HgeneSUPT5Hchr19:39936605chr19:16594926ENST00000599117+331924_930251088.0RepeatNote=CTR2-8
HgeneSUPT5Hchr19:39936605chr19:16594926ENST00000599117+331932_939251088.0RepeatNote=CTR2-9
HgeneSUPT5Hchr19:39936605chr19:16594926ENST00000599117+331943_950251088.0RepeatNote=CTR2-10
TgeneCALR3chr19:39936605chr19:16594926ENST000002698813920_197164385.0RegionNote=N-domain


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Fusion Gene Sequence for SUPT5H-CALR3


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>88149_88149_1_SUPT5H-CALR3_SUPT5H_chr19_39936605_ENST00000359191_CALR3_chr19_16594926_ENST00000269881_length(transcript)=1059nt_BP=322nt
GCGTGTGCAGAGGTGGCAGTTCCGGGCGCCGGGGAGGTGTAGAGAACAGATTCGGAAACTGGGGAGGTCTAGCATGTGGCGTAGGAGGGG
GTCCTCACTCCGCTTCGCGATTGCCAAAACGAGCCTGCCGGAAGCGCCCTAAGGGGTTTTCTTCTCCCAGGGAACCAGCGGGGAAACTGA
GGCTCGGGGTGGAGCGCAGGATTGTGGGACGCGCCAAGGCTGCTGTCTTTCCCAGCAGCAGCGGAAGATGTCGGACAGCGAGGACAGCAA
CTTTTCCGAGGAGGAGGACAGCGAGCGCAGCAGTGACGGCGAGGAGGCCGAGGTTGATGGCTTCACACACCTGTACACTCTAATTTTAAG
ACCAGATCTTTCTTATGATGTGAAAATTGATGGTCAGTCAATTGAATCCGGCAGCATAGAGTACGACTGGAACTTAACATCACTCAAGAA
GGAAACGTCCCCGGCAGAATCGAAGGATTGGGAACAGACTAAAGACAACAAAGCCCAGGACTGGGAGAAGCATTTTCTGGACGCCAGCAC
CAGCAAGCAGAGCGACTGGAACGGTGACCTGGATGGGGACTGGCCAGCGCCGATGCTCCAGAAGCCCCCGTACCAGGATGGCCTGAAACC
AGAAGGTATTCATAAAGACGTCTGGCTCCACCGTAAGATGAAGAATACCGACTATTTGACGCAGTATGACCTCTCAGAATTTGAGAACAT
TGGTGCCATTGGCCTGGAGCTTTGGCAGGTGAGATCTGGAACCATTTTTGATAACTTTCTGATCACAGATGATGAAGAGTACGCAGATAA
TTTTGGCAAGGCCACCTGGGGCGAAACCAAGGGTCCAGAAAGGGAGATGGATGCCATACAGGCCAAGGAGGAAATGAAGAAGGCCCGCGA
GGAAGAGGAGGAAGAGCTGCTGTCGGGAAAAATTAACAGGCACGAACATTACTTCAATCAATTTCACAGAAGGAATGAACTTTAGTGATC

>88149_88149_1_SUPT5H-CALR3_SUPT5H_chr19_39936605_ENST00000359191_CALR3_chr19_16594926_ENST00000269881_length(amino acids)=245AA_BP=25
MSDSEDSNFSEEEDSERSSDGEEAEVDGFTHLYTLILRPDLSYDVKIDGQSIESGSIEYDWNLTSLKKETSPAESKDWEQTKDNKAQDWE
KHFLDASTSKQSDWNGDLDGDWPAPMLQKPPYQDGLKPEGIHKDVWLHRKMKNTDYLTQYDLSEFENIGAIGLELWQVRSGTIFDNFLIT

--------------------------------------------------------------
>88149_88149_2_SUPT5H-CALR3_SUPT5H_chr19_39936605_ENST00000359191_CALR3_chr19_16594926_ENST00000602234_length(transcript)=910nt_BP=322nt
GCGTGTGCAGAGGTGGCAGTTCCGGGCGCCGGGGAGGTGTAGAGAACAGATTCGGAAACTGGGGAGGTCTAGCATGTGGCGTAGGAGGGG
GTCCTCACTCCGCTTCGCGATTGCCAAAACGAGCCTGCCGGAAGCGCCCTAAGGGGTTTTCTTCTCCCAGGGAACCAGCGGGGAAACTGA
GGCTCGGGGTGGAGCGCAGGATTGTGGGACGCGCCAAGGCTGCTGTCTTTCCCAGCAGCAGCGGAAGATGTCGGACAGCGAGGACAGCAA
CTTTTCCGAGGAGGAGGACAGCGAGCGCAGCAGTGACGGCGAGGAGGCCGAGTGATGGCTTCACACACCTGTACACTCTAATTTTAAGAC
CAGATCTTTCTTATGATGTGAAAATTGATGGTCAGTCAATTGAATCCGGCAGCATAGAGTACGACTGGAACTTAACATCACTCAAGAAGG
AAACGTCCCCGGCAGAATCGAAGGATTGGGAACAGACTAAAGACAACAAAGCCCAGGTGTGAATTTTTCCTGGGCAACTCTAAAAAGTGC
ACAAATGTAGTTTGTAAGTACCCAGTTACTGGACAATTGCTGCATGGCTGGTAGCCACGATGGCAATATTATAGAACCAAATGCCCTCCC
CAGAGCACACACTGCAGACCAGCCACATCTCTACACATCTGAAGGACTGGGAGAAGCATTTTCTGGACGCCAGCACCAGCAAGCAGAGCG
ACTGGAACGGTGACCTGGATGGGGACTGGCCAGCGCCGATGCTCCAGAAGCCCCCGTACCAGGATGGCCTGAAACCAGAAGGTATTCATA
AAGACGTCTGGCTCCACCGTAAGATGAAGAATACCGACTATTTGACGCAGTATGACCTCTCAGAATTTGAGAACATTGGTGCCATTGGCC

>88149_88149_2_SUPT5H-CALR3_SUPT5H_chr19_39936605_ENST00000359191_CALR3_chr19_16594926_ENST00000602234_length(amino acids)=133AA_BP=71
MPKRACRKRPKGFSSPREPAGKLRLGVERRIVGRAKAAVFPSSSGRCRTARTATFPRRRTASAAVTARRPSDGFTHLYTLILRPDLSYDV

--------------------------------------------------------------
>88149_88149_3_SUPT5H-CALR3_SUPT5H_chr19_39936605_ENST00000402194_CALR3_chr19_16594926_ENST00000269881_length(transcript)=991nt_BP=254nt
AACGGGTAGGTTCTCGCGAGAGGACCCGTCAGCCCCAGTCAGGCGTCGTGCGAACAGCAGCTGGTACCGAAGGCGGAGGTGGAGCCCGAG
AGGGAACCAGCGGGGAAACTGAGGCTCGGGGTGGAGCGCAGGATTGTGGGACGCGCCAAGGCTGCTGTCTTTCCCAGCAGCAGCGGAAGA
TGTCGGACAGCGAGGACAGCAACTTTTCCGAGGAGGAGGACAGCGAGCGCAGCAGTGACGGCGAGGAGGCCGAGGTTGATGGCTTCACAC
ACCTGTACACTCTAATTTTAAGACCAGATCTTTCTTATGATGTGAAAATTGATGGTCAGTCAATTGAATCCGGCAGCATAGAGTACGACT
GGAACTTAACATCACTCAAGAAGGAAACGTCCCCGGCAGAATCGAAGGATTGGGAACAGACTAAAGACAACAAAGCCCAGGACTGGGAGA
AGCATTTTCTGGACGCCAGCACCAGCAAGCAGAGCGACTGGAACGGTGACCTGGATGGGGACTGGCCAGCGCCGATGCTCCAGAAGCCCC
CGTACCAGGATGGCCTGAAACCAGAAGGTATTCATAAAGACGTCTGGCTCCACCGTAAGATGAAGAATACCGACTATTTGACGCAGTATG
ACCTCTCAGAATTTGAGAACATTGGTGCCATTGGCCTGGAGCTTTGGCAGGTGAGATCTGGAACCATTTTTGATAACTTTCTGATCACAG
ATGATGAAGAGTACGCAGATAATTTTGGCAAGGCCACCTGGGGCGAAACCAAGGGTCCAGAAAGGGAGATGGATGCCATACAGGCCAAGG
AGGAAATGAAGAAGGCCCGCGAGGAAGAGGAGGAAGAGCTGCTGTCGGGAAAAATTAACAGGCACGAACATTACTTCAATCAATTTCACA
GAAGGAATGAACTTTAGTGATCCCCATTGGATATAAGGATGACTGGTAAAATCTCATTGCTACTTTAATCTATGTTTCAAACTCAAATGT

>88149_88149_3_SUPT5H-CALR3_SUPT5H_chr19_39936605_ENST00000402194_CALR3_chr19_16594926_ENST00000269881_length(amino acids)=245AA_BP=25
MSDSEDSNFSEEEDSERSSDGEEAEVDGFTHLYTLILRPDLSYDVKIDGQSIESGSIEYDWNLTSLKKETSPAESKDWEQTKDNKAQDWE
KHFLDASTSKQSDWNGDLDGDWPAPMLQKPPYQDGLKPEGIHKDVWLHRKMKNTDYLTQYDLSEFENIGAIGLELWQVRSGTIFDNFLIT

--------------------------------------------------------------
>88149_88149_4_SUPT5H-CALR3_SUPT5H_chr19_39936605_ENST00000402194_CALR3_chr19_16594926_ENST00000602234_length(transcript)=842nt_BP=254nt
AACGGGTAGGTTCTCGCGAGAGGACCCGTCAGCCCCAGTCAGGCGTCGTGCGAACAGCAGCTGGTACCGAAGGCGGAGGTGGAGCCCGAG
AGGGAACCAGCGGGGAAACTGAGGCTCGGGGTGGAGCGCAGGATTGTGGGACGCGCCAAGGCTGCTGTCTTTCCCAGCAGCAGCGGAAGA
TGTCGGACAGCGAGGACAGCAACTTTTCCGAGGAGGAGGACAGCGAGCGCAGCAGTGACGGCGAGGAGGCCGAGTGATGGCTTCACACAC
CTGTACACTCTAATTTTAAGACCAGATCTTTCTTATGATGTGAAAATTGATGGTCAGTCAATTGAATCCGGCAGCATAGAGTACGACTGG
AACTTAACATCACTCAAGAAGGAAACGTCCCCGGCAGAATCGAAGGATTGGGAACAGACTAAAGACAACAAAGCCCAGGTGTGAATTTTT
CCTGGGCAACTCTAAAAAGTGCACAAATGTAGTTTGTAAGTACCCAGTTACTGGACAATTGCTGCATGGCTGGTAGCCACGATGGCAATA
TTATAGAACCAAATGCCCTCCCCAGAGCACACACTGCAGACCAGCCACATCTCTACACATCTGAAGGACTGGGAGAAGCATTTTCTGGAC
GCCAGCACCAGCAAGCAGAGCGACTGGAACGGTGACCTGGATGGGGACTGGCCAGCGCCGATGCTCCAGAAGCCCCCGTACCAGGATGGC
CTGAAACCAGAAGGTATTCATAAAGACGTCTGGCTCCACCGTAAGATGAAGAATACCGACTATTTGACGCAGTATGACCTCTCAGAATTT

>88149_88149_4_SUPT5H-CALR3_SUPT5H_chr19_39936605_ENST00000402194_CALR3_chr19_16594926_ENST00000602234_length(amino acids)=127AA_BP=65
MVPKAEVEPEREPAGKLRLGVERRIVGRAKAAVFPSSSGRCRTARTATFPRRRTASAAVTARRPSDGFTHLYTLILRPDLSYDVKIDGQS

--------------------------------------------------------------
>88149_88149_5_SUPT5H-CALR3_SUPT5H_chr19_39936605_ENST00000432763_CALR3_chr19_16594926_ENST00000269881_length(transcript)=991nt_BP=254nt
AACGGGTAGGTTCTCGCGAGAGGACCCGTCAGCCCCAGTCAGGCGTCGTGCGAACAGCAGCTGGTACCGAAGGCGGAGGTGGAGCCCGAG
AGGGAACCAGCGGGGAAACTGAGGCTCGGGGTGGAGCGCAGGATTGTGGGACGCGCCAAGGCTGCTGTCTTTCCCAGCAGCAGCGGAAGA
TGTCGGACAGCGAGGACAGCAACTTTTCCGAGGAGGAGGACAGCGAGCGCAGCAGTGACGGCGAGGAGGCCGAGGTTGATGGCTTCACAC
ACCTGTACACTCTAATTTTAAGACCAGATCTTTCTTATGATGTGAAAATTGATGGTCAGTCAATTGAATCCGGCAGCATAGAGTACGACT
GGAACTTAACATCACTCAAGAAGGAAACGTCCCCGGCAGAATCGAAGGATTGGGAACAGACTAAAGACAACAAAGCCCAGGACTGGGAGA
AGCATTTTCTGGACGCCAGCACCAGCAAGCAGAGCGACTGGAACGGTGACCTGGATGGGGACTGGCCAGCGCCGATGCTCCAGAAGCCCC
CGTACCAGGATGGCCTGAAACCAGAAGGTATTCATAAAGACGTCTGGCTCCACCGTAAGATGAAGAATACCGACTATTTGACGCAGTATG
ACCTCTCAGAATTTGAGAACATTGGTGCCATTGGCCTGGAGCTTTGGCAGGTGAGATCTGGAACCATTTTTGATAACTTTCTGATCACAG
ATGATGAAGAGTACGCAGATAATTTTGGCAAGGCCACCTGGGGCGAAACCAAGGGTCCAGAAAGGGAGATGGATGCCATACAGGCCAAGG
AGGAAATGAAGAAGGCCCGCGAGGAAGAGGAGGAAGAGCTGCTGTCGGGAAAAATTAACAGGCACGAACATTACTTCAATCAATTTCACA
GAAGGAATGAACTTTAGTGATCCCCATTGGATATAAGGATGACTGGTAAAATCTCATTGCTACTTTAATCTATGTTTCAAACTCAAATGT

>88149_88149_5_SUPT5H-CALR3_SUPT5H_chr19_39936605_ENST00000432763_CALR3_chr19_16594926_ENST00000269881_length(amino acids)=245AA_BP=25
MSDSEDSNFSEEEDSERSSDGEEAEVDGFTHLYTLILRPDLSYDVKIDGQSIESGSIEYDWNLTSLKKETSPAESKDWEQTKDNKAQDWE
KHFLDASTSKQSDWNGDLDGDWPAPMLQKPPYQDGLKPEGIHKDVWLHRKMKNTDYLTQYDLSEFENIGAIGLELWQVRSGTIFDNFLIT

--------------------------------------------------------------
>88149_88149_6_SUPT5H-CALR3_SUPT5H_chr19_39936605_ENST00000432763_CALR3_chr19_16594926_ENST00000602234_length(transcript)=842nt_BP=254nt
AACGGGTAGGTTCTCGCGAGAGGACCCGTCAGCCCCAGTCAGGCGTCGTGCGAACAGCAGCTGGTACCGAAGGCGGAGGTGGAGCCCGAG
AGGGAACCAGCGGGGAAACTGAGGCTCGGGGTGGAGCGCAGGATTGTGGGACGCGCCAAGGCTGCTGTCTTTCCCAGCAGCAGCGGAAGA
TGTCGGACAGCGAGGACAGCAACTTTTCCGAGGAGGAGGACAGCGAGCGCAGCAGTGACGGCGAGGAGGCCGAGTGATGGCTTCACACAC
CTGTACACTCTAATTTTAAGACCAGATCTTTCTTATGATGTGAAAATTGATGGTCAGTCAATTGAATCCGGCAGCATAGAGTACGACTGG
AACTTAACATCACTCAAGAAGGAAACGTCCCCGGCAGAATCGAAGGATTGGGAACAGACTAAAGACAACAAAGCCCAGGTGTGAATTTTT
CCTGGGCAACTCTAAAAAGTGCACAAATGTAGTTTGTAAGTACCCAGTTACTGGACAATTGCTGCATGGCTGGTAGCCACGATGGCAATA
TTATAGAACCAAATGCCCTCCCCAGAGCACACACTGCAGACCAGCCACATCTCTACACATCTGAAGGACTGGGAGAAGCATTTTCTGGAC
GCCAGCACCAGCAAGCAGAGCGACTGGAACGGTGACCTGGATGGGGACTGGCCAGCGCCGATGCTCCAGAAGCCCCCGTACCAGGATGGC
CTGAAACCAGAAGGTATTCATAAAGACGTCTGGCTCCACCGTAAGATGAAGAATACCGACTATTTGACGCAGTATGACCTCTCAGAATTT

>88149_88149_6_SUPT5H-CALR3_SUPT5H_chr19_39936605_ENST00000432763_CALR3_chr19_16594926_ENST00000602234_length(amino acids)=127AA_BP=65
MVPKAEVEPEREPAGKLRLGVERRIVGRAKAAVFPSSSGRCRTARTATFPRRRTASAAVTARRPSDGFTHLYTLILRPDLSYDVKIDGQS

--------------------------------------------------------------
>88149_88149_7_SUPT5H-CALR3_SUPT5H_chr19_39936605_ENST00000598725_CALR3_chr19_16594926_ENST00000269881_length(transcript)=1019nt_BP=282nt
AGAGAACAGATTCGGAAACTGGGGAGGTCTAGCATGTGGCGTAGGAGGGGGTCCTCACTCCGCTTCGCGATTGCCAAAACGAGCCTGCCG
GAAGCGCCCTAAGGGGTTTTCTTCTCCCAGGGAACCAGCGGGGAAACTGAGGCTCGGGGTGGAGCGCAGGATTGTGGGACGCGCCAAGGC
TGCTGTCTTTCCCAGCAGCAGCGGAAGATGTCGGACAGCGAGGACAGCAACTTTTCCGAGGAGGAGGACAGCGAGCGCAGCAGTGACGGC
GAGGAGGCCGAGGTTGATGGCTTCACACACCTGTACACTCTAATTTTAAGACCAGATCTTTCTTATGATGTGAAAATTGATGGTCAGTCA
ATTGAATCCGGCAGCATAGAGTACGACTGGAACTTAACATCACTCAAGAAGGAAACGTCCCCGGCAGAATCGAAGGATTGGGAACAGACT
AAAGACAACAAAGCCCAGGACTGGGAGAAGCATTTTCTGGACGCCAGCACCAGCAAGCAGAGCGACTGGAACGGTGACCTGGATGGGGAC
TGGCCAGCGCCGATGCTCCAGAAGCCCCCGTACCAGGATGGCCTGAAACCAGAAGGTATTCATAAAGACGTCTGGCTCCACCGTAAGATG
AAGAATACCGACTATTTGACGCAGTATGACCTCTCAGAATTTGAGAACATTGGTGCCATTGGCCTGGAGCTTTGGCAGGTGAGATCTGGA
ACCATTTTTGATAACTTTCTGATCACAGATGATGAAGAGTACGCAGATAATTTTGGCAAGGCCACCTGGGGCGAAACCAAGGGTCCAGAA
AGGGAGATGGATGCCATACAGGCCAAGGAGGAAATGAAGAAGGCCCGCGAGGAAGAGGAGGAAGAGCTGCTGTCGGGAAAAATTAACAGG
CACGAACATTACTTCAATCAATTTCACAGAAGGAATGAACTTTAGTGATCCCCATTGGATATAAGGATGACTGGTAAAATCTCATTGCTA

>88149_88149_7_SUPT5H-CALR3_SUPT5H_chr19_39936605_ENST00000598725_CALR3_chr19_16594926_ENST00000269881_length(amino acids)=245AA_BP=25
MSDSEDSNFSEEEDSERSSDGEEAEVDGFTHLYTLILRPDLSYDVKIDGQSIESGSIEYDWNLTSLKKETSPAESKDWEQTKDNKAQDWE
KHFLDASTSKQSDWNGDLDGDWPAPMLQKPPYQDGLKPEGIHKDVWLHRKMKNTDYLTQYDLSEFENIGAIGLELWQVRSGTIFDNFLIT

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>88149_88149_8_SUPT5H-CALR3_SUPT5H_chr19_39936605_ENST00000598725_CALR3_chr19_16594926_ENST00000602234_length(transcript)=870nt_BP=282nt
AGAGAACAGATTCGGAAACTGGGGAGGTCTAGCATGTGGCGTAGGAGGGGGTCCTCACTCCGCTTCGCGATTGCCAAAACGAGCCTGCCG
GAAGCGCCCTAAGGGGTTTTCTTCTCCCAGGGAACCAGCGGGGAAACTGAGGCTCGGGGTGGAGCGCAGGATTGTGGGACGCGCCAAGGC
TGCTGTCTTTCCCAGCAGCAGCGGAAGATGTCGGACAGCGAGGACAGCAACTTTTCCGAGGAGGAGGACAGCGAGCGCAGCAGTGACGGC
GAGGAGGCCGAGTGATGGCTTCACACACCTGTACACTCTAATTTTAAGACCAGATCTTTCTTATGATGTGAAAATTGATGGTCAGTCAAT
TGAATCCGGCAGCATAGAGTACGACTGGAACTTAACATCACTCAAGAAGGAAACGTCCCCGGCAGAATCGAAGGATTGGGAACAGACTAA
AGACAACAAAGCCCAGGTGTGAATTTTTCCTGGGCAACTCTAAAAAGTGCACAAATGTAGTTTGTAAGTACCCAGTTACTGGACAATTGC
TGCATGGCTGGTAGCCACGATGGCAATATTATAGAACCAAATGCCCTCCCCAGAGCACACACTGCAGACCAGCCACATCTCTACACATCT
GAAGGACTGGGAGAAGCATTTTCTGGACGCCAGCACCAGCAAGCAGAGCGACTGGAACGGTGACCTGGATGGGGACTGGCCAGCGCCGAT
GCTCCAGAAGCCCCCGTACCAGGATGGCCTGAAACCAGAAGGTATTCATAAAGACGTCTGGCTCCACCGTAAGATGAAGAATACCGACTA

>88149_88149_8_SUPT5H-CALR3_SUPT5H_chr19_39936605_ENST00000598725_CALR3_chr19_16594926_ENST00000602234_length(amino acids)=133AA_BP=71
MPKRACRKRPKGFSSPREPAGKLRLGVERRIVGRAKAAVFPSSSGRCRTARTATFPRRRTASAAVTARRPSDGFTHLYTLILRPDLSYDV

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>88149_88149_9_SUPT5H-CALR3_SUPT5H_chr19_39936605_ENST00000599117_CALR3_chr19_16594926_ENST00000269881_length(transcript)=1179nt_BP=442nt
AAGCCTTTTCTTCCCTCTAGGCCAGAGGACCCCACCTGGAGCCCTAGTAGCCAAGGGGAAGAGTTAAGAAGGAGGAAAGTAAGATGTCGG
CCCCGCACTCCGCCCAGGCCAGCCCTGCCTCTCTCAAGATGGCGACCTGGAAGTGCGTCGCCCGTGCCAGCCCCGGAAATCTCGTGTTAG
GCGAGGTCAACGGGTAGGTTCTCGCGAGAGGACCCGTCAGCCCCAGTCAGGCGTCGTGCGAACAGCAGCTGGTACCGAAGGCGGAGGTGG
AGCCCGAGAGGGAACCAGCGGGGAAACTGAGGCTCGGGGTGGAGCGCAGGATTGTGGGACGCGCCAAGGCTGCTGTCTTTCCCAGCAGCA
GCGGAAGATGTCGGACAGCGAGGACAGCAACTTTTCCGAGGAGGAGGACAGCGAGCGCAGCAGTGACGGCGAGGAGGCCGAGGTTGATGG
CTTCACACACCTGTACACTCTAATTTTAAGACCAGATCTTTCTTATGATGTGAAAATTGATGGTCAGTCAATTGAATCCGGCAGCATAGA
GTACGACTGGAACTTAACATCACTCAAGAAGGAAACGTCCCCGGCAGAATCGAAGGATTGGGAACAGACTAAAGACAACAAAGCCCAGGA
CTGGGAGAAGCATTTTCTGGACGCCAGCACCAGCAAGCAGAGCGACTGGAACGGTGACCTGGATGGGGACTGGCCAGCGCCGATGCTCCA
GAAGCCCCCGTACCAGGATGGCCTGAAACCAGAAGGTATTCATAAAGACGTCTGGCTCCACCGTAAGATGAAGAATACCGACTATTTGAC
GCAGTATGACCTCTCAGAATTTGAGAACATTGGTGCCATTGGCCTGGAGCTTTGGCAGGTGAGATCTGGAACCATTTTTGATAACTTTCT
GATCACAGATGATGAAGAGTACGCAGATAATTTTGGCAAGGCCACCTGGGGCGAAACCAAGGGTCCAGAAAGGGAGATGGATGCCATACA
GGCCAAGGAGGAAATGAAGAAGGCCCGCGAGGAAGAGGAGGAAGAGCTGCTGTCGGGAAAAATTAACAGGCACGAACATTACTTCAATCA
ATTTCACAGAAGGAATGAACTTTAGTGATCCCCATTGGATATAAGGATGACTGGTAAAATCTCATTGCTACTTTAATCTATGTTTCAAAC

>88149_88149_9_SUPT5H-CALR3_SUPT5H_chr19_39936605_ENST00000599117_CALR3_chr19_16594926_ENST00000269881_length(amino acids)=322AA_BP=102
MEVRRPCQPRKSRVRRGQRVGSRERTRQPQSGVVRTAAGTEGGGGAREGTSGETEARGGAQDCGTRQGCCLSQQQRKMSDSEDSNFSEEE
DSERSSDGEEAEVDGFTHLYTLILRPDLSYDVKIDGQSIESGSIEYDWNLTSLKKETSPAESKDWEQTKDNKAQDWEKHFLDASTSKQSD
WNGDLDGDWPAPMLQKPPYQDGLKPEGIHKDVWLHRKMKNTDYLTQYDLSEFENIGAIGLELWQVRSGTIFDNFLITDDEEYADNFGKAT

--------------------------------------------------------------
>88149_88149_10_SUPT5H-CALR3_SUPT5H_chr19_39936605_ENST00000599117_CALR3_chr19_16594926_ENST00000602234_length(transcript)=1030nt_BP=442nt
AAGCCTTTTCTTCCCTCTAGGCCAGAGGACCCCACCTGGAGCCCTAGTAGCCAAGGGGAAGAGTTAAGAAGGAGGAAAGTAAGATGTCGG
CCCCGCACTCCGCCCAGGCCAGCCCTGCCTCTCTCAAGATGGCGACCTGGAAGTGCGTCGCCCGTGCCAGCCCCGGAAATCTCGTGTTAG
GCGAGGTCAACGGGTAGGTTCTCGCGAGAGGACCCGTCAGCCCCAGTCAGGCGTCGTGCGAACAGCAGCTGGTACCGAAGGCGGAGGTGG
AGCCCGAGAGGGAACCAGCGGGGAAACTGAGGCTCGGGGTGGAGCGCAGGATTGTGGGACGCGCCAAGGCTGCTGTCTTTCCCAGCAGCA
GCGGAAGATGTCGGACAGCGAGGACAGCAACTTTTCCGAGGAGGAGGACAGCGAGCGCAGCAGTGACGGCGAGGAGGCCGAGTGATGGCT
TCACACACCTGTACACTCTAATTTTAAGACCAGATCTTTCTTATGATGTGAAAATTGATGGTCAGTCAATTGAATCCGGCAGCATAGAGT
ACGACTGGAACTTAACATCACTCAAGAAGGAAACGTCCCCGGCAGAATCGAAGGATTGGGAACAGACTAAAGACAACAAAGCCCAGGTGT
GAATTTTTCCTGGGCAACTCTAAAAAGTGCACAAATGTAGTTTGTAAGTACCCAGTTACTGGACAATTGCTGCATGGCTGGTAGCCACGA
TGGCAATATTATAGAACCAAATGCCCTCCCCAGAGCACACACTGCAGACCAGCCACATCTCTACACATCTGAAGGACTGGGAGAAGCATT
TTCTGGACGCCAGCACCAGCAAGCAGAGCGACTGGAACGGTGACCTGGATGGGGACTGGCCAGCGCCGATGCTCCAGAAGCCCCCGTACC
AGGATGGCCTGAAACCAGAAGGTATTCATAAAGACGTCTGGCTCCACCGTAAGATGAAGAATACCGACTATTTGACGCAGTATGACCTCT

>88149_88149_10_SUPT5H-CALR3_SUPT5H_chr19_39936605_ENST00000599117_CALR3_chr19_16594926_ENST00000602234_length(amino acids)=127AA_BP=65
MVPKAEVEPEREPAGKLRLGVERRIVGRAKAAVFPSSSGRCRTARTATFPRRRTASAAVTARRPSDGFTHLYTLILRPDLSYDVKIDGQS

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Fusion Gene PPI Analysis for SUPT5H-CALR3


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with
HgeneSUPT5Hchr19:39936605chr19:16594926ENST00000359191+128313_42025.01084.0RNA polymerase II
HgeneSUPT5Hchr19:39936605chr19:16594926ENST00000402194+229313_42025.01084.0RNA polymerase II
HgeneSUPT5Hchr19:39936605chr19:16594926ENST00000432763+230313_42025.01088.0RNA polymerase II
HgeneSUPT5Hchr19:39936605chr19:16594926ENST00000598725+129313_42025.01088.0RNA polymerase II
HgeneSUPT5Hchr19:39936605chr19:16594926ENST00000599117+331313_42025.01088.0RNA polymerase II
HgeneSUPT5Hchr19:39936605chr19:16594926ENST00000359191+128176_27025.01084.0SUPT4H1
HgeneSUPT5Hchr19:39936605chr19:16594926ENST00000402194+229176_27025.01084.0SUPT4H1
HgeneSUPT5Hchr19:39936605chr19:16594926ENST00000432763+230176_27025.01088.0SUPT4H1
HgeneSUPT5Hchr19:39936605chr19:16594926ENST00000598725+129176_27025.01088.0SUPT4H1
HgeneSUPT5Hchr19:39936605chr19:16594926ENST00000599117+331176_27025.01088.0SUPT4H1


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for SUPT5H-CALR3


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for SUPT5H-CALR3


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource