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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:SUPT5H-EGLN2 (FusionGDB2 ID:88152)

Fusion Gene Summary for SUPT5H-EGLN2

check button Fusion gene summary
Fusion gene informationFusion gene name: SUPT5H-EGLN2
Fusion gene ID: 88152
HgeneTgene
Gene symbol

SUPT5H

EGLN2

Gene ID

6829

100529264

Gene nameSPT5 homolog, DSIF elongation factor subunitRAB4B-EGLN2 readthrough (NMD candidate)
SynonymsSPT5|SPT5H|Tat-CT1EGLN2|EIT-6|EIT6|HIF-PH1|HPH-1|HPH-3|PHD1|RERT-lncRNA
Cytomap

19q13.2

19q13.2

Type of geneprotein-codingncRNA
Descriptiontranscription elongation factor SPT5DRB sensitivity-inducing factor 160 kDa subunitDRB sensitivity-inducing factor large subunitDSIF large subunitDSIF p160Tat-cotransactivator 1 proteinhSPT5suppressor of Ty 5 homologEgl nine homolog 2Estrogen-induced tag 6HIF-prolyl hydroxylase 1Hypoxia-inducible factor prolyl hydroxylase 1Prolyl hydroxylase domain-containing protein 1RAB4B-EGLN2 readthrough (non-protein coding)RAB4B-EGLN2 readthrough long non-coding RNA
Modification date2020031320200313
UniProtAcc.

Q96KS0

Ensembl transtripts involved in fusion geneENST00000359191, ENST00000402194, 
ENST00000432763, ENST00000598725, 
ENST00000599117, 		ENST00000303961, 
ENST00000406058, ENST00000594140, 
ENST00000593726, 
Fusion gene scores* DoF score17 X 13 X 9=19892 X 2 X 2=8
# samples 192
** MAII scorelog2(19/1989*10)=-3.3879719525028
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(2/8*10)=1.32192809488736
Context

PubMed: SUPT5H [Title/Abstract] AND EGLN2 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointSUPT5H(39948380)-EGLN2(41313714), # samples:1
Anticipated loss of major functional domain due to fusion event.SUPT5H-EGLN2 seems lost the major protein functional domain in Hgene partner, which is a essential gene due to the frame-shifted ORF.
SUPT5H-EGLN2 seems lost the major protein functional domain in Tgene partner, which is a IUPHAR drug target due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneSUPT5H

GO:0000122

negative regulation of transcription by RNA polymerase II

9450929

HgeneSUPT5H

GO:0006368

transcription elongation from RNA polymerase II promoter

9450929

HgeneSUPT5H

GO:0032785

negative regulation of DNA-templated transcription, elongation

9450929

HgeneSUPT5H

GO:0032786

positive regulation of DNA-templated transcription, elongation

9450929

HgeneSUPT5H

GO:0045944

positive regulation of transcription by RNA polymerase II

9450929


check buttonFusion gene breakpoints across SUPT5H (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across EGLN2 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4GBMTCGA-14-0787-01ASUPT5Hchr19

39948380

+EGLN2chr19

41313714

+


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Fusion Gene ORF analysis for SUPT5H-EGLN2

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
Frame-shiftENST00000359191ENST00000303961SUPT5Hchr19

39948380

+EGLN2chr19

41313714

+
Frame-shiftENST00000359191ENST00000406058SUPT5Hchr19

39948380

+EGLN2chr19

41313714

+
Frame-shiftENST00000359191ENST00000594140SUPT5Hchr19

39948380

+EGLN2chr19

41313714

+
Frame-shiftENST00000402194ENST00000303961SUPT5Hchr19

39948380

+EGLN2chr19

41313714

+
Frame-shiftENST00000402194ENST00000406058SUPT5Hchr19

39948380

+EGLN2chr19

41313714

+
Frame-shiftENST00000402194ENST00000594140SUPT5Hchr19

39948380

+EGLN2chr19

41313714

+
Frame-shiftENST00000432763ENST00000303961SUPT5Hchr19

39948380

+EGLN2chr19

41313714

+
Frame-shiftENST00000432763ENST00000406058SUPT5Hchr19

39948380

+EGLN2chr19

41313714

+
Frame-shiftENST00000432763ENST00000594140SUPT5Hchr19

39948380

+EGLN2chr19

41313714

+
Frame-shiftENST00000598725ENST00000303961SUPT5Hchr19

39948380

+EGLN2chr19

41313714

+
Frame-shiftENST00000598725ENST00000406058SUPT5Hchr19

39948380

+EGLN2chr19

41313714

+
Frame-shiftENST00000598725ENST00000594140SUPT5Hchr19

39948380

+EGLN2chr19

41313714

+
Frame-shiftENST00000599117ENST00000303961SUPT5Hchr19

39948380

+EGLN2chr19

41313714

+
Frame-shiftENST00000599117ENST00000406058SUPT5Hchr19

39948380

+EGLN2chr19

41313714

+
Frame-shiftENST00000599117ENST00000594140SUPT5Hchr19

39948380

+EGLN2chr19

41313714

+
In-frameENST00000359191ENST00000593726SUPT5Hchr19

39948380

+EGLN2chr19

41313714

+
In-frameENST00000402194ENST00000593726SUPT5Hchr19

39948380

+EGLN2chr19

41313714

+
In-frameENST00000432763ENST00000593726SUPT5Hchr19

39948380

+EGLN2chr19

41313714

+
In-frameENST00000598725ENST00000593726SUPT5Hchr19

39948380

+EGLN2chr19

41313714

+
In-frameENST00000599117ENST00000593726SUPT5Hchr19

39948380

+EGLN2chr19

41313714

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000599117SUPT5Hchr1939948380+ENST00000593726EGLN2chr1941313714+1299674136729197
ENST00000432763SUPT5Hchr1939948380+ENST00000593726EGLN2chr1941313714+111148647428148
ENST00000402194SUPT5Hchr1939948380+ENST00000593726EGLN2chr1941313714+111148647428148
ENST00000359191SUPT5Hchr1939948380+ENST00000593726EGLN2chr1941313714+1179554542138134
ENST00000598725SUPT5Hchr1939948380+ENST00000593726EGLN2chr1941313714+113951450298134

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000599117ENST00000593726SUPT5Hchr1939948380+EGLN2chr1941313714+0.0018563590.9981437
ENST00000432763ENST00000593726SUPT5Hchr1939948380+EGLN2chr1941313714+0.0014042280.9985958
ENST00000402194ENST00000593726SUPT5Hchr1939948380+EGLN2chr1941313714+0.0014042280.9985958
ENST00000359191ENST00000593726SUPT5Hchr1939948380+EGLN2chr1941313714+0.0025625160.9974375
ENST00000598725ENST00000593726SUPT5Hchr1939948380+EGLN2chr1941313714+0.002386850.9976132

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Fusion Genomic Features for SUPT5H-EGLN2


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
SUPT5Hchr1939948380+EGLN2chr1941313713+0.0001395130.9998605
SUPT5Hchr1939948380+EGLN2chr1941313713+0.0001395130.9998605

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for SUPT5H-EGLN2


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr19:39948380/chr19:41313714)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
.EGLN2

Q96KS0

FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Prolyl hydroxylase that mediates hydroxylation of proline residues in target proteins, such as ATF4, IKBKB, CEP192 and HIF1A (PubMed:11595184, PubMed:12039559, PubMed:15925519, PubMed:16509823, PubMed:17114296, PubMed:23932902). Target proteins are preferentially recognized via a LXXLAP motif (PubMed:11595184, PubMed:12039559, PubMed:15925519). Cellular oxygen sensor that catalyzes, under normoxic conditions, the post-translational formation of 4-hydroxyproline in hypoxia-inducible factor (HIF) alpha proteins (PubMed:11595184, PubMed:12039559, PubMed:12181324, PubMed:15925519, PubMed:19339211). Hydroxylates a specific proline found in each of the oxygen-dependent degradation (ODD) domains (N-terminal, NODD, and C-terminal, CODD) of HIF1A (PubMed:11595184, PubMed:12039559, PubMed:12181324, PubMed:15925519). Also hydroxylates HIF2A (PubMed:11595184, PubMed:12039559, PubMed:15925519). Has a preference for the CODD site for both HIF1A and HIF2A (PubMed:11595184, PubMed:12039559, PubMed:15925519). Hydroxylated HIFs are then targeted for proteasomal degradation via the von Hippel-Lindau ubiquitination complex (PubMed:11595184, PubMed:12039559, PubMed:15925519). Under hypoxic conditions, the hydroxylation reaction is attenuated allowing HIFs to escape degradation resulting in their translocation to the nucleus, heterodimerization with HIF1B, and increased expression of hypoxy-inducible genes (PubMed:11595184, PubMed:12039559, PubMed:15925519). EGLN2 is involved in regulating hypoxia tolerance and apoptosis in cardiac and skeletal muscle (PubMed:11595184, PubMed:12039559, PubMed:15925519). Also regulates susceptibility to normoxic oxidative neuronal death (PubMed:11595184, PubMed:12039559, PubMed:15925519). Links oxygen sensing to cell cycle and primary cilia formation by hydroxylating the critical centrosome component CEP192 which promotes its ubiquitination and subsequent proteasomal degradation (PubMed:23932902). Hydroxylates IKBKB, mediating NF-kappa-B activation in hypoxic conditions (PubMed:17114296). Also mediates hydroxylation of ATF4, leading to decreased protein stability of ATF4 (By similarity). {ECO:0000250|UniProtKB:Q91YE2, ECO:0000269|PubMed:11595184, ECO:0000269|PubMed:12039559, ECO:0000269|PubMed:12181324, ECO:0000269|PubMed:15925519, ECO:0000269|PubMed:16509823, ECO:0000269|PubMed:17114296, ECO:0000269|PubMed:19339211, ECO:0000269|PubMed:23932902}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneEGLN2chr19:39948380chr19:41313714ENST0000059414035278_376107126.0DomainFe2OG dioxygenase
TgeneEGLN2chr19:39948380chr19:41313714ENST0000059414035225_235107126.0RegionBeta(2)beta(3) 'finger-like' loop

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneSUPT5Hchr19:39948380chr19:41313714ENST00000359191+32811_1061021084.0Compositional biasNote=Glu-rich
HgeneSUPT5Hchr19:39948380chr19:41313714ENST00000359191+328844_9681021084.0Compositional biasNote=Pro-rich
HgeneSUPT5Hchr19:39948380chr19:41313714ENST00000402194+42911_1061021084.0Compositional biasNote=Glu-rich
HgeneSUPT5Hchr19:39948380chr19:41313714ENST00000402194+429844_9681021084.0Compositional biasNote=Pro-rich
HgeneSUPT5Hchr19:39948380chr19:41313714ENST00000432763+43011_1061021088.0Compositional biasNote=Glu-rich
HgeneSUPT5Hchr19:39948380chr19:41313714ENST00000432763+430844_9681021088.0Compositional biasNote=Pro-rich
HgeneSUPT5Hchr19:39948380chr19:41313714ENST00000598725+32911_1061021088.0Compositional biasNote=Glu-rich
HgeneSUPT5Hchr19:39948380chr19:41313714ENST00000598725+329844_9681021088.0Compositional biasNote=Pro-rich
HgeneSUPT5Hchr19:39948380chr19:41313714ENST00000599117+53111_1061021088.0Compositional biasNote=Glu-rich
HgeneSUPT5Hchr19:39948380chr19:41313714ENST00000599117+531844_9681021088.0Compositional biasNote=Pro-rich
HgeneSUPT5Hchr19:39948380chr19:41313714ENST00000359191+328273_3061021084.0DomainNote=KOW 1
HgeneSUPT5Hchr19:39948380chr19:41313714ENST00000359191+328420_4511021084.0DomainNote=KOW 2
HgeneSUPT5Hchr19:39948380chr19:41313714ENST00000359191+328472_5031021084.0DomainNote=KOW 3
HgeneSUPT5Hchr19:39948380chr19:41313714ENST00000359191+328594_6271021084.0DomainNote=KOW 4
HgeneSUPT5Hchr19:39948380chr19:41313714ENST00000359191+328704_7371021084.0DomainNote=KOW 5
HgeneSUPT5Hchr19:39948380chr19:41313714ENST00000402194+429273_3061021084.0DomainNote=KOW 1
HgeneSUPT5Hchr19:39948380chr19:41313714ENST00000402194+429420_4511021084.0DomainNote=KOW 2
HgeneSUPT5Hchr19:39948380chr19:41313714ENST00000402194+429472_5031021084.0DomainNote=KOW 3
HgeneSUPT5Hchr19:39948380chr19:41313714ENST00000402194+429594_6271021084.0DomainNote=KOW 4
HgeneSUPT5Hchr19:39948380chr19:41313714ENST00000402194+429704_7371021084.0DomainNote=KOW 5
HgeneSUPT5Hchr19:39948380chr19:41313714ENST00000432763+430273_3061021088.0DomainNote=KOW 1
HgeneSUPT5Hchr19:39948380chr19:41313714ENST00000432763+430420_4511021088.0DomainNote=KOW 2
HgeneSUPT5Hchr19:39948380chr19:41313714ENST00000432763+430472_5031021088.0DomainNote=KOW 3
HgeneSUPT5Hchr19:39948380chr19:41313714ENST00000432763+430594_6271021088.0DomainNote=KOW 4
HgeneSUPT5Hchr19:39948380chr19:41313714ENST00000432763+430704_7371021088.0DomainNote=KOW 5
HgeneSUPT5Hchr19:39948380chr19:41313714ENST00000598725+329273_3061021088.0DomainNote=KOW 1
HgeneSUPT5Hchr19:39948380chr19:41313714ENST00000598725+329420_4511021088.0DomainNote=KOW 2
HgeneSUPT5Hchr19:39948380chr19:41313714ENST00000598725+329472_5031021088.0DomainNote=KOW 3
HgeneSUPT5Hchr19:39948380chr19:41313714ENST00000598725+329594_6271021088.0DomainNote=KOW 4
HgeneSUPT5Hchr19:39948380chr19:41313714ENST00000598725+329704_7371021088.0DomainNote=KOW 5
HgeneSUPT5Hchr19:39948380chr19:41313714ENST00000599117+531273_3061021088.0DomainNote=KOW 1
HgeneSUPT5Hchr19:39948380chr19:41313714ENST00000599117+531420_4511021088.0DomainNote=KOW 2
HgeneSUPT5Hchr19:39948380chr19:41313714ENST00000599117+531472_5031021088.0DomainNote=KOW 3
HgeneSUPT5Hchr19:39948380chr19:41313714ENST00000599117+531594_6271021088.0DomainNote=KOW 4
HgeneSUPT5Hchr19:39948380chr19:41313714ENST00000599117+531704_7371021088.0DomainNote=KOW 5
HgeneSUPT5Hchr19:39948380chr19:41313714ENST00000359191+328754_8171021084.0RegionNote=9 X 7 AA approximate tandem repeats of G-S-[QR]-T-P-X-[YQ]%2C motif CTR1
HgeneSUPT5Hchr19:39948380chr19:41313714ENST00000359191+328844_9501021084.0RegionNote=10 X 8 AA approximate tandem repeats of P-[TS]-P-S-P-[QA]-[SG]-Y%2C motif CTR2
HgeneSUPT5Hchr19:39948380chr19:41313714ENST00000402194+429754_8171021084.0RegionNote=9 X 7 AA approximate tandem repeats of G-S-[QR]-T-P-X-[YQ]%2C motif CTR1
HgeneSUPT5Hchr19:39948380chr19:41313714ENST00000402194+429844_9501021084.0RegionNote=10 X 8 AA approximate tandem repeats of P-[TS]-P-S-P-[QA]-[SG]-Y%2C motif CTR2
HgeneSUPT5Hchr19:39948380chr19:41313714ENST00000432763+430754_8171021088.0RegionNote=9 X 7 AA approximate tandem repeats of G-S-[QR]-T-P-X-[YQ]%2C motif CTR1
HgeneSUPT5Hchr19:39948380chr19:41313714ENST00000432763+430844_9501021088.0RegionNote=10 X 8 AA approximate tandem repeats of P-[TS]-P-S-P-[QA]-[SG]-Y%2C motif CTR2
HgeneSUPT5Hchr19:39948380chr19:41313714ENST00000598725+329754_8171021088.0RegionNote=9 X 7 AA approximate tandem repeats of G-S-[QR]-T-P-X-[YQ]%2C motif CTR1
HgeneSUPT5Hchr19:39948380chr19:41313714ENST00000598725+329844_9501021088.0RegionNote=10 X 8 AA approximate tandem repeats of P-[TS]-P-S-P-[QA]-[SG]-Y%2C motif CTR2
HgeneSUPT5Hchr19:39948380chr19:41313714ENST00000599117+531754_8171021088.0RegionNote=9 X 7 AA approximate tandem repeats of G-S-[QR]-T-P-X-[YQ]%2C motif CTR1
HgeneSUPT5Hchr19:39948380chr19:41313714ENST00000599117+531844_9501021088.0RegionNote=10 X 8 AA approximate tandem repeats of P-[TS]-P-S-P-[QA]-[SG]-Y%2C motif CTR2
HgeneSUPT5Hchr19:39948380chr19:41313714ENST00000359191+328754_7591021084.0RepeatNote=CTR1-1%3B approximate
HgeneSUPT5Hchr19:39948380chr19:41313714ENST00000359191+328760_7651021084.0RepeatNote=CTR1-2
HgeneSUPT5Hchr19:39948380chr19:41313714ENST00000359191+328766_7711021084.0RepeatNote=CTR1-3
HgeneSUPT5Hchr19:39948380chr19:41313714ENST00000359191+328772_7781021084.0RepeatNote=CTR1-4
HgeneSUPT5Hchr19:39948380chr19:41313714ENST00000359191+328781_7871021084.0RepeatNote=CTR1-5
HgeneSUPT5Hchr19:39948380chr19:41313714ENST00000359191+328788_7941021084.0RepeatNote=CTR1-6
HgeneSUPT5Hchr19:39948380chr19:41313714ENST00000359191+328796_8021021084.0RepeatNote=CTR1-7
HgeneSUPT5Hchr19:39948380chr19:41313714ENST00000359191+328803_8091021084.0RepeatNote=CTR1-8
HgeneSUPT5Hchr19:39948380chr19:41313714ENST00000359191+328811_8171021084.0RepeatNote=CTR1-9
HgeneSUPT5Hchr19:39948380chr19:41313714ENST00000359191+328844_8511021084.0RepeatNote=CTR2-1
HgeneSUPT5Hchr19:39948380chr19:41313714ENST00000359191+328854_8621021084.0RepeatNote=CTR2-2%3B approximate
HgeneSUPT5Hchr19:39948380chr19:41313714ENST00000359191+328863_8691021084.0RepeatNote=CTR2-3%3B approximate
HgeneSUPT5Hchr19:39948380chr19:41313714ENST00000359191+328881_8851021084.0RepeatNote=CTR2-4%3B half-length
HgeneSUPT5Hchr19:39948380chr19:41313714ENST00000359191+328896_9021021084.0RepeatNote=CTR2-5%3B approximate
HgeneSUPT5Hchr19:39948380chr19:41313714ENST00000359191+328904_9111021084.0RepeatNote=CTR2-6
HgeneSUPT5Hchr19:39948380chr19:41313714ENST00000359191+328916_9211021084.0RepeatNote=CTR2-7%3B approximate
HgeneSUPT5Hchr19:39948380chr19:41313714ENST00000359191+328924_9301021084.0RepeatNote=CTR2-8
HgeneSUPT5Hchr19:39948380chr19:41313714ENST00000359191+328932_9391021084.0RepeatNote=CTR2-9
HgeneSUPT5Hchr19:39948380chr19:41313714ENST00000359191+328943_9501021084.0RepeatNote=CTR2-10
HgeneSUPT5Hchr19:39948380chr19:41313714ENST00000402194+429754_7591021084.0RepeatNote=CTR1-1%3B approximate
HgeneSUPT5Hchr19:39948380chr19:41313714ENST00000402194+429760_7651021084.0RepeatNote=CTR1-2
HgeneSUPT5Hchr19:39948380chr19:41313714ENST00000402194+429766_7711021084.0RepeatNote=CTR1-3
HgeneSUPT5Hchr19:39948380chr19:41313714ENST00000402194+429772_7781021084.0RepeatNote=CTR1-4
HgeneSUPT5Hchr19:39948380chr19:41313714ENST00000402194+429781_7871021084.0RepeatNote=CTR1-5
HgeneSUPT5Hchr19:39948380chr19:41313714ENST00000402194+429788_7941021084.0RepeatNote=CTR1-6
HgeneSUPT5Hchr19:39948380chr19:41313714ENST00000402194+429796_8021021084.0RepeatNote=CTR1-7
HgeneSUPT5Hchr19:39948380chr19:41313714ENST00000402194+429803_8091021084.0RepeatNote=CTR1-8
HgeneSUPT5Hchr19:39948380chr19:41313714ENST00000402194+429811_8171021084.0RepeatNote=CTR1-9
HgeneSUPT5Hchr19:39948380chr19:41313714ENST00000402194+429844_8511021084.0RepeatNote=CTR2-1
HgeneSUPT5Hchr19:39948380chr19:41313714ENST00000402194+429854_8621021084.0RepeatNote=CTR2-2%3B approximate
HgeneSUPT5Hchr19:39948380chr19:41313714ENST00000402194+429863_8691021084.0RepeatNote=CTR2-3%3B approximate
HgeneSUPT5Hchr19:39948380chr19:41313714ENST00000402194+429881_8851021084.0RepeatNote=CTR2-4%3B half-length
HgeneSUPT5Hchr19:39948380chr19:41313714ENST00000402194+429896_9021021084.0RepeatNote=CTR2-5%3B approximate
HgeneSUPT5Hchr19:39948380chr19:41313714ENST00000402194+429904_9111021084.0RepeatNote=CTR2-6
HgeneSUPT5Hchr19:39948380chr19:41313714ENST00000402194+429916_9211021084.0RepeatNote=CTR2-7%3B approximate
HgeneSUPT5Hchr19:39948380chr19:41313714ENST00000402194+429924_9301021084.0RepeatNote=CTR2-8
HgeneSUPT5Hchr19:39948380chr19:41313714ENST00000402194+429932_9391021084.0RepeatNote=CTR2-9
HgeneSUPT5Hchr19:39948380chr19:41313714ENST00000402194+429943_9501021084.0RepeatNote=CTR2-10
HgeneSUPT5Hchr19:39948380chr19:41313714ENST00000432763+430754_7591021088.0RepeatNote=CTR1-1%3B approximate
HgeneSUPT5Hchr19:39948380chr19:41313714ENST00000432763+430760_7651021088.0RepeatNote=CTR1-2
HgeneSUPT5Hchr19:39948380chr19:41313714ENST00000432763+430766_7711021088.0RepeatNote=CTR1-3
HgeneSUPT5Hchr19:39948380chr19:41313714ENST00000432763+430772_7781021088.0RepeatNote=CTR1-4
HgeneSUPT5Hchr19:39948380chr19:41313714ENST00000432763+430781_7871021088.0RepeatNote=CTR1-5
HgeneSUPT5Hchr19:39948380chr19:41313714ENST00000432763+430788_7941021088.0RepeatNote=CTR1-6
HgeneSUPT5Hchr19:39948380chr19:41313714ENST00000432763+430796_8021021088.0RepeatNote=CTR1-7
HgeneSUPT5Hchr19:39948380chr19:41313714ENST00000432763+430803_8091021088.0RepeatNote=CTR1-8
HgeneSUPT5Hchr19:39948380chr19:41313714ENST00000432763+430811_8171021088.0RepeatNote=CTR1-9
HgeneSUPT5Hchr19:39948380chr19:41313714ENST00000432763+430844_8511021088.0RepeatNote=CTR2-1
HgeneSUPT5Hchr19:39948380chr19:41313714ENST00000432763+430854_8621021088.0RepeatNote=CTR2-2%3B approximate
HgeneSUPT5Hchr19:39948380chr19:41313714ENST00000432763+430863_8691021088.0RepeatNote=CTR2-3%3B approximate
HgeneSUPT5Hchr19:39948380chr19:41313714ENST00000432763+430881_8851021088.0RepeatNote=CTR2-4%3B half-length
HgeneSUPT5Hchr19:39948380chr19:41313714ENST00000432763+430896_9021021088.0RepeatNote=CTR2-5%3B approximate
HgeneSUPT5Hchr19:39948380chr19:41313714ENST00000432763+430904_9111021088.0RepeatNote=CTR2-6
HgeneSUPT5Hchr19:39948380chr19:41313714ENST00000432763+430916_9211021088.0RepeatNote=CTR2-7%3B approximate
HgeneSUPT5Hchr19:39948380chr19:41313714ENST00000432763+430924_9301021088.0RepeatNote=CTR2-8
HgeneSUPT5Hchr19:39948380chr19:41313714ENST00000432763+430932_9391021088.0RepeatNote=CTR2-9
HgeneSUPT5Hchr19:39948380chr19:41313714ENST00000432763+430943_9501021088.0RepeatNote=CTR2-10
HgeneSUPT5Hchr19:39948380chr19:41313714ENST00000598725+329754_7591021088.0RepeatNote=CTR1-1%3B approximate
HgeneSUPT5Hchr19:39948380chr19:41313714ENST00000598725+329760_7651021088.0RepeatNote=CTR1-2
HgeneSUPT5Hchr19:39948380chr19:41313714ENST00000598725+329766_7711021088.0RepeatNote=CTR1-3
HgeneSUPT5Hchr19:39948380chr19:41313714ENST00000598725+329772_7781021088.0RepeatNote=CTR1-4
HgeneSUPT5Hchr19:39948380chr19:41313714ENST00000598725+329781_7871021088.0RepeatNote=CTR1-5
HgeneSUPT5Hchr19:39948380chr19:41313714ENST00000598725+329788_7941021088.0RepeatNote=CTR1-6
HgeneSUPT5Hchr19:39948380chr19:41313714ENST00000598725+329796_8021021088.0RepeatNote=CTR1-7
HgeneSUPT5Hchr19:39948380chr19:41313714ENST00000598725+329803_8091021088.0RepeatNote=CTR1-8
HgeneSUPT5Hchr19:39948380chr19:41313714ENST00000598725+329811_8171021088.0RepeatNote=CTR1-9
HgeneSUPT5Hchr19:39948380chr19:41313714ENST00000598725+329844_8511021088.0RepeatNote=CTR2-1
HgeneSUPT5Hchr19:39948380chr19:41313714ENST00000598725+329854_8621021088.0RepeatNote=CTR2-2%3B approximate
HgeneSUPT5Hchr19:39948380chr19:41313714ENST00000598725+329863_8691021088.0RepeatNote=CTR2-3%3B approximate
HgeneSUPT5Hchr19:39948380chr19:41313714ENST00000598725+329881_8851021088.0RepeatNote=CTR2-4%3B half-length
HgeneSUPT5Hchr19:39948380chr19:41313714ENST00000598725+329896_9021021088.0RepeatNote=CTR2-5%3B approximate
HgeneSUPT5Hchr19:39948380chr19:41313714ENST00000598725+329904_9111021088.0RepeatNote=CTR2-6
HgeneSUPT5Hchr19:39948380chr19:41313714ENST00000598725+329916_9211021088.0RepeatNote=CTR2-7%3B approximate
HgeneSUPT5Hchr19:39948380chr19:41313714ENST00000598725+329924_9301021088.0RepeatNote=CTR2-8
HgeneSUPT5Hchr19:39948380chr19:41313714ENST00000598725+329932_9391021088.0RepeatNote=CTR2-9
HgeneSUPT5Hchr19:39948380chr19:41313714ENST00000598725+329943_9501021088.0RepeatNote=CTR2-10
HgeneSUPT5Hchr19:39948380chr19:41313714ENST00000599117+531754_7591021088.0RepeatNote=CTR1-1%3B approximate
HgeneSUPT5Hchr19:39948380chr19:41313714ENST00000599117+531760_7651021088.0RepeatNote=CTR1-2
HgeneSUPT5Hchr19:39948380chr19:41313714ENST00000599117+531766_7711021088.0RepeatNote=CTR1-3
HgeneSUPT5Hchr19:39948380chr19:41313714ENST00000599117+531772_7781021088.0RepeatNote=CTR1-4
HgeneSUPT5Hchr19:39948380chr19:41313714ENST00000599117+531781_7871021088.0RepeatNote=CTR1-5
HgeneSUPT5Hchr19:39948380chr19:41313714ENST00000599117+531788_7941021088.0RepeatNote=CTR1-6
HgeneSUPT5Hchr19:39948380chr19:41313714ENST00000599117+531796_8021021088.0RepeatNote=CTR1-7
HgeneSUPT5Hchr19:39948380chr19:41313714ENST00000599117+531803_8091021088.0RepeatNote=CTR1-8
HgeneSUPT5Hchr19:39948380chr19:41313714ENST00000599117+531811_8171021088.0RepeatNote=CTR1-9
HgeneSUPT5Hchr19:39948380chr19:41313714ENST00000599117+531844_8511021088.0RepeatNote=CTR2-1
HgeneSUPT5Hchr19:39948380chr19:41313714ENST00000599117+531854_8621021088.0RepeatNote=CTR2-2%3B approximate
HgeneSUPT5Hchr19:39948380chr19:41313714ENST00000599117+531863_8691021088.0RepeatNote=CTR2-3%3B approximate
HgeneSUPT5Hchr19:39948380chr19:41313714ENST00000599117+531881_8851021088.0RepeatNote=CTR2-4%3B half-length
HgeneSUPT5Hchr19:39948380chr19:41313714ENST00000599117+531896_9021021088.0RepeatNote=CTR2-5%3B approximate
HgeneSUPT5Hchr19:39948380chr19:41313714ENST00000599117+531904_9111021088.0RepeatNote=CTR2-6
HgeneSUPT5Hchr19:39948380chr19:41313714ENST00000599117+531916_9211021088.0RepeatNote=CTR2-7%3B approximate
HgeneSUPT5Hchr19:39948380chr19:41313714ENST00000599117+531924_9301021088.0RepeatNote=CTR2-8
HgeneSUPT5Hchr19:39948380chr19:41313714ENST00000599117+531932_9391021088.0RepeatNote=CTR2-9
HgeneSUPT5Hchr19:39948380chr19:41313714ENST00000599117+531943_9501021088.0RepeatNote=CTR2-10
TgeneEGLN2chr19:39948380chr19:41313714ENST0000030396146278_376389408.0DomainFe2OG dioxygenase
TgeneEGLN2chr19:39948380chr19:41313714ENST0000040605846278_376389408.0DomainFe2OG dioxygenase
TgeneEGLN2chr19:39948380chr19:41313714ENST0000059372635278_376389408.0DomainFe2OG dioxygenase
TgeneEGLN2chr19:39948380chr19:41313714ENST000003039614689_134389408.0MotifBipartite nuclear localization signal
TgeneEGLN2chr19:39948380chr19:41313714ENST000004060584689_134389408.0MotifBipartite nuclear localization signal
TgeneEGLN2chr19:39948380chr19:41313714ENST000005937263589_134389408.0MotifBipartite nuclear localization signal
TgeneEGLN2chr19:39948380chr19:41313714ENST000005941403589_134107126.0MotifBipartite nuclear localization signal
TgeneEGLN2chr19:39948380chr19:41313714ENST0000030396146225_235389408.0RegionBeta(2)beta(3) 'finger-like' loop
TgeneEGLN2chr19:39948380chr19:41313714ENST0000040605846225_235389408.0RegionBeta(2)beta(3) 'finger-like' loop
TgeneEGLN2chr19:39948380chr19:41313714ENST0000059372635225_235389408.0RegionBeta(2)beta(3) 'finger-like' loop


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Fusion Gene Sequence for SUPT5H-EGLN2


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>88152_88152_1_SUPT5H-EGLN2_SUPT5H_chr19_39948380_ENST00000359191_EGLN2_chr19_41313714_ENST00000593726_length(transcript)=1179nt_BP=554nt
GCGTGTGCAGAGGTGGCAGTTCCGGGCGCCGGGGAGGTGTAGAGAACAGATTCGGAAACTGGGGAGGTCTAGCATGTGGCGTAGGAGGGG
GTCCTCACTCCGCTTCGCGATTGCCAAAACGAGCCTGCCGGAAGCGCCCTAAGGGGTTTTCTTCTCCCAGGGAACCAGCGGGGAAACTGA
GGCTCGGGGTGGAGCGCAGGATTGTGGGACGCGCCAAGGCTGCTGTCTTTCCCAGCAGCAGCGGAAGATGTCGGACAGCGAGGACAGCAA
CTTTTCCGAGGAGGAGGACAGCGAGCGCAGCAGTGACGGCGAGGAGGCCGAGGTAGACGAAGAGCGGCGGAGTGCAGCGGGCAGTGAGAA
AGAAGAAGAGCCTGAGGACGAAGAGGAGGAGGAAGAGGAGGAGGAATACGATGAGGAAGAGGAGGAAGAAGATGATGACCGACCCCCCAA
GAAACCCCGCCATGGAGGCTTCATTCTGGACGAGGCTGATGTTGACGATGAGTATGAGGACGAGGACCAGTGGGAGGATGGAGCAGAGGA
CATTCTAGAGAAAGCATCAGGACAGAAAGGTGTCCAAGTACCTGTATCACAGCCGCCTACGCCCACCTAGTGGCCAGTCCCAGAGCCGCA
TGGCAGACAGCTTAAATGACTTCAGGAGAGCCCTGGGCCTGTGCTGGCTGCTCCTTCCCTGCCACCGCTGCTGCTTCTGACTTTGCCTCT
GTCCTGCCTGGTGTGGAGGGCTCTGTCTGTTGCTGAGGACCAAGGAGGAGAAGAGACCTTTGCTGCCCCATCATGGGGGCTGGGGTTGTC
ACCTGGACAGGGGGCAGCCGTGGAGGCCACCGTTACCAACTGAAGCTGGGGGCCTGGGTCCTACCCTGTCTGGTCATGACCCCATTAGGT
ATGGAGAGCTGGGAGGAGGCATTGTCACTTCCCACCAGGATGCAGGACTTGGGGTTGAGGTGAGTCATGGCCTCTTGCTGGCAATGGGGT
GGGAGGAGTACCCCCAAGTCCTCTCACTCCTCCAGCCTGGAATGTGAAGTGACTCCCCAACCCCTTTGGCCATGGCAGGCACCTTTTGGA
CTGGGCTGCCACTGCTTGGGCAGAGTAAAAGGTGCCAGGAGGAGCATGGGTGTGGAAGTCCTGTCAGCCAAGAAATAAAAGTTTACCTCA

>88152_88152_1_SUPT5H-EGLN2_SUPT5H_chr19_39948380_ENST00000359191_EGLN2_chr19_41313714_ENST00000593726_length(amino acids)=134AA_BP=4
MSSAPSSHWSSSSYSSSTSASSRMKPPWRGFLGGRSSSSSSSSSSYSSSSSSSSSSSGSSSFSLPAALRRSSSTSASSPSLLRSLSSSSE

--------------------------------------------------------------
>88152_88152_2_SUPT5H-EGLN2_SUPT5H_chr19_39948380_ENST00000402194_EGLN2_chr19_41313714_ENST00000593726_length(transcript)=1111nt_BP=486nt
AACGGGTAGGTTCTCGCGAGAGGACCCGTCAGCCCCAGTCAGGCGTCGTGCGAACAGCAGCTGGTACCGAAGGCGGAGGTGGAGCCCGAG
AGGGAACCAGCGGGGAAACTGAGGCTCGGGGTGGAGCGCAGGATTGTGGGACGCGCCAAGGCTGCTGTCTTTCCCAGCAGCAGCGGAAGA
TGTCGGACAGCGAGGACAGCAACTTTTCCGAGGAGGAGGACAGCGAGCGCAGCAGTGACGGCGAGGAGGCCGAGGTAGACGAAGAGCGGC
GGAGTGCAGCGGGCAGTGAGAAAGAAGAAGAGCCTGAGGACGAAGAGGAGGAGGAAGAGGAGGAGGAATACGATGAGGAAGAGGAGGAAG
AAGATGATGACCGACCCCCCAAGAAACCCCGCCATGGAGGCTTCATTCTGGACGAGGCTGATGTTGACGATGAGTATGAGGACGAGGACC
AGTGGGAGGATGGAGCAGAGGACATTCTAGAGAAAGCATCAGGACAGAAAGGTGTCCAAGTACCTGTATCACAGCCGCCTACGCCCACCT
AGTGGCCAGTCCCAGAGCCGCATGGCAGACAGCTTAAATGACTTCAGGAGAGCCCTGGGCCTGTGCTGGCTGCTCCTTCCCTGCCACCGC
TGCTGCTTCTGACTTTGCCTCTGTCCTGCCTGGTGTGGAGGGCTCTGTCTGTTGCTGAGGACCAAGGAGGAGAAGAGACCTTTGCTGCCC
CATCATGGGGGCTGGGGTTGTCACCTGGACAGGGGGCAGCCGTGGAGGCCACCGTTACCAACTGAAGCTGGGGGCCTGGGTCCTACCCTG
TCTGGTCATGACCCCATTAGGTATGGAGAGCTGGGAGGAGGCATTGTCACTTCCCACCAGGATGCAGGACTTGGGGTTGAGGTGAGTCAT
GGCCTCTTGCTGGCAATGGGGTGGGAGGAGTACCCCCAAGTCCTCTCACTCCTCCAGCCTGGAATGTGAAGTGACTCCCCAACCCCTTTG
GCCATGGCAGGCACCTTTTGGACTGGGCTGCCACTGCTTGGGCAGAGTAAAAGGTGCCAGGAGGAGCATGGGTGTGGAAGTCCTGTCAGC

>88152_88152_2_SUPT5H-EGLN2_SUPT5H_chr19_39948380_ENST00000402194_EGLN2_chr19_41313714_ENST00000593726_length(amino acids)=148AA_BP=4
MSSAPSSHWSSSSYSSSTSASSRMKPPWRGFLGGRSSSSSSSSSSYSSSSSSSSSSSGSSSFSLPAALRRSSSTSASSPSLLRSLSSSSE

--------------------------------------------------------------
>88152_88152_3_SUPT5H-EGLN2_SUPT5H_chr19_39948380_ENST00000432763_EGLN2_chr19_41313714_ENST00000593726_length(transcript)=1111nt_BP=486nt
AACGGGTAGGTTCTCGCGAGAGGACCCGTCAGCCCCAGTCAGGCGTCGTGCGAACAGCAGCTGGTACCGAAGGCGGAGGTGGAGCCCGAG
AGGGAACCAGCGGGGAAACTGAGGCTCGGGGTGGAGCGCAGGATTGTGGGACGCGCCAAGGCTGCTGTCTTTCCCAGCAGCAGCGGAAGA
TGTCGGACAGCGAGGACAGCAACTTTTCCGAGGAGGAGGACAGCGAGCGCAGCAGTGACGGCGAGGAGGCCGAGGTAGACGAAGAGCGGC
GGAGTGCAGCGGGCAGTGAGAAAGAAGAAGAGCCTGAGGACGAAGAGGAGGAGGAAGAGGAGGAGGAATACGATGAGGAAGAGGAGGAAG
AAGATGATGACCGACCCCCCAAGAAACCCCGCCATGGAGGCTTCATTCTGGACGAGGCTGATGTTGACGATGAGTATGAGGACGAGGACC
AGTGGGAGGATGGAGCAGAGGACATTCTAGAGAAAGCATCAGGACAGAAAGGTGTCCAAGTACCTGTATCACAGCCGCCTACGCCCACCT
AGTGGCCAGTCCCAGAGCCGCATGGCAGACAGCTTAAATGACTTCAGGAGAGCCCTGGGCCTGTGCTGGCTGCTCCTTCCCTGCCACCGC
TGCTGCTTCTGACTTTGCCTCTGTCCTGCCTGGTGTGGAGGGCTCTGTCTGTTGCTGAGGACCAAGGAGGAGAAGAGACCTTTGCTGCCC
CATCATGGGGGCTGGGGTTGTCACCTGGACAGGGGGCAGCCGTGGAGGCCACCGTTACCAACTGAAGCTGGGGGCCTGGGTCCTACCCTG
TCTGGTCATGACCCCATTAGGTATGGAGAGCTGGGAGGAGGCATTGTCACTTCCCACCAGGATGCAGGACTTGGGGTTGAGGTGAGTCAT
GGCCTCTTGCTGGCAATGGGGTGGGAGGAGTACCCCCAAGTCCTCTCACTCCTCCAGCCTGGAATGTGAAGTGACTCCCCAACCCCTTTG
GCCATGGCAGGCACCTTTTGGACTGGGCTGCCACTGCTTGGGCAGAGTAAAAGGTGCCAGGAGGAGCATGGGTGTGGAAGTCCTGTCAGC

>88152_88152_3_SUPT5H-EGLN2_SUPT5H_chr19_39948380_ENST00000432763_EGLN2_chr19_41313714_ENST00000593726_length(amino acids)=148AA_BP=4
MSSAPSSHWSSSSYSSSTSASSRMKPPWRGFLGGRSSSSSSSSSSYSSSSSSSSSSSGSSSFSLPAALRRSSSTSASSPSLLRSLSSSSE

--------------------------------------------------------------
>88152_88152_4_SUPT5H-EGLN2_SUPT5H_chr19_39948380_ENST00000598725_EGLN2_chr19_41313714_ENST00000593726_length(transcript)=1139nt_BP=514nt
AGAGAACAGATTCGGAAACTGGGGAGGTCTAGCATGTGGCGTAGGAGGGGGTCCTCACTCCGCTTCGCGATTGCCAAAACGAGCCTGCCG
GAAGCGCCCTAAGGGGTTTTCTTCTCCCAGGGAACCAGCGGGGAAACTGAGGCTCGGGGTGGAGCGCAGGATTGTGGGACGCGCCAAGGC
TGCTGTCTTTCCCAGCAGCAGCGGAAGATGTCGGACAGCGAGGACAGCAACTTTTCCGAGGAGGAGGACAGCGAGCGCAGCAGTGACGGC
GAGGAGGCCGAGGTAGACGAAGAGCGGCGGAGTGCAGCGGGCAGTGAGAAAGAAGAAGAGCCTGAGGACGAAGAGGAGGAGGAAGAGGAG
GAGGAATACGATGAGGAAGAGGAGGAAGAAGATGATGACCGACCCCCCAAGAAACCCCGCCATGGAGGCTTCATTCTGGACGAGGCTGAT
GTTGACGATGAGTATGAGGACGAGGACCAGTGGGAGGATGGAGCAGAGGACATTCTAGAGAAAGCATCAGGACAGAAAGGTGTCCAAGTA
CCTGTATCACAGCCGCCTACGCCCACCTAGTGGCCAGTCCCAGAGCCGCATGGCAGACAGCTTAAATGACTTCAGGAGAGCCCTGGGCCT
GTGCTGGCTGCTCCTTCCCTGCCACCGCTGCTGCTTCTGACTTTGCCTCTGTCCTGCCTGGTGTGGAGGGCTCTGTCTGTTGCTGAGGAC
CAAGGAGGAGAAGAGACCTTTGCTGCCCCATCATGGGGGCTGGGGTTGTCACCTGGACAGGGGGCAGCCGTGGAGGCCACCGTTACCAAC
TGAAGCTGGGGGCCTGGGTCCTACCCTGTCTGGTCATGACCCCATTAGGTATGGAGAGCTGGGAGGAGGCATTGTCACTTCCCACCAGGA
TGCAGGACTTGGGGTTGAGGTGAGTCATGGCCTCTTGCTGGCAATGGGGTGGGAGGAGTACCCCCAAGTCCTCTCACTCCTCCAGCCTGG
AATGTGAAGTGACTCCCCAACCCCTTTGGCCATGGCAGGCACCTTTTGGACTGGGCTGCCACTGCTTGGGCAGAGTAAAAGGTGCCAGGA

>88152_88152_4_SUPT5H-EGLN2_SUPT5H_chr19_39948380_ENST00000598725_EGLN2_chr19_41313714_ENST00000593726_length(amino acids)=134AA_BP=4
MSSAPSSHWSSSSYSSSTSASSRMKPPWRGFLGGRSSSSSSSSSSYSSSSSSSSSSSGSSSFSLPAALRRSSSTSASSPSLLRSLSSSSE

--------------------------------------------------------------
>88152_88152_5_SUPT5H-EGLN2_SUPT5H_chr19_39948380_ENST00000599117_EGLN2_chr19_41313714_ENST00000593726_length(transcript)=1299nt_BP=674nt
AAGCCTTTTCTTCCCTCTAGGCCAGAGGACCCCACCTGGAGCCCTAGTAGCCAAGGGGAAGAGTTAAGAAGGAGGAAAGTAAGATGTCGG
CCCCGCACTCCGCCCAGGCCAGCCCTGCCTCTCTCAAGATGGCGACCTGGAAGTGCGTCGCCCGTGCCAGCCCCGGAAATCTCGTGTTAG
GCGAGGTCAACGGGTAGGTTCTCGCGAGAGGACCCGTCAGCCCCAGTCAGGCGTCGTGCGAACAGCAGCTGGTACCGAAGGCGGAGGTGG
AGCCCGAGAGGGAACCAGCGGGGAAACTGAGGCTCGGGGTGGAGCGCAGGATTGTGGGACGCGCCAAGGCTGCTGTCTTTCCCAGCAGCA
GCGGAAGATGTCGGACAGCGAGGACAGCAACTTTTCCGAGGAGGAGGACAGCGAGCGCAGCAGTGACGGCGAGGAGGCCGAGGTAGACGA
AGAGCGGCGGAGTGCAGCGGGCAGTGAGAAAGAAGAAGAGCCTGAGGACGAAGAGGAGGAGGAAGAGGAGGAGGAATACGATGAGGAAGA
GGAGGAAGAAGATGATGACCGACCCCCCAAGAAACCCCGCCATGGAGGCTTCATTCTGGACGAGGCTGATGTTGACGATGAGTATGAGGA
CGAGGACCAGTGGGAGGATGGAGCAGAGGACATTCTAGAGAAAGCATCAGGACAGAAAGGTGTCCAAGTACCTGTATCACAGCCGCCTAC
GCCCACCTAGTGGCCAGTCCCAGAGCCGCATGGCAGACAGCTTAAATGACTTCAGGAGAGCCCTGGGCCTGTGCTGGCTGCTCCTTCCCT
GCCACCGCTGCTGCTTCTGACTTTGCCTCTGTCCTGCCTGGTGTGGAGGGCTCTGTCTGTTGCTGAGGACCAAGGAGGAGAAGAGACCTT
TGCTGCCCCATCATGGGGGCTGGGGTTGTCACCTGGACAGGGGGCAGCCGTGGAGGCCACCGTTACCAACTGAAGCTGGGGGCCTGGGTC
CTACCCTGTCTGGTCATGACCCCATTAGGTATGGAGAGCTGGGAGGAGGCATTGTCACTTCCCACCAGGATGCAGGACTTGGGGTTGAGG
TGAGTCATGGCCTCTTGCTGGCAATGGGGTGGGAGGAGTACCCCCAAGTCCTCTCACTCCTCCAGCCTGGAATGTGAAGTGACTCCCCAA
CCCCTTTGGCCATGGCAGGCACCTTTTGGACTGGGCTGCCACTGCTTGGGCAGAGTAAAAGGTGCCAGGAGGAGCATGGGTGTGGAAGTC

>88152_88152_5_SUPT5H-EGLN2_SUPT5H_chr19_39948380_ENST00000599117_EGLN2_chr19_41313714_ENST00000593726_length(amino acids)=197AA_BP=179
MEVRRPCQPRKSRVRRGQRVGSRERTRQPQSGVVRTAAGTEGGGGAREGTSGETEARGGAQDCGTRQGCCLSQQQRKMSDSEDSNFSEEE
DSERSSDGEEAEVDEERRSAAGSEKEEEPEDEEEEEEEEEYDEEEEEEDDDRPPKKPRHGGFILDEADVDDEYEDEDQWEDGAEDILEKA

--------------------------------------------------------------

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Fusion Gene PPI Analysis for SUPT5H-EGLN2


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with
HgeneSUPT5Hchr19:39948380chr19:41313714ENST00000359191+328313_420102.333333333333331084.0RNA polymerase II
HgeneSUPT5Hchr19:39948380chr19:41313714ENST00000402194+429313_420102.333333333333331084.0RNA polymerase II
HgeneSUPT5Hchr19:39948380chr19:41313714ENST00000432763+430313_420102.333333333333331088.0RNA polymerase II
HgeneSUPT5Hchr19:39948380chr19:41313714ENST00000598725+329313_420102.333333333333331088.0RNA polymerase II
HgeneSUPT5Hchr19:39948380chr19:41313714ENST00000599117+531313_420102.333333333333331088.0RNA polymerase II
HgeneSUPT5Hchr19:39948380chr19:41313714ENST00000359191+328176_270102.333333333333331084.0SUPT4H1
HgeneSUPT5Hchr19:39948380chr19:41313714ENST00000402194+429176_270102.333333333333331084.0SUPT4H1
HgeneSUPT5Hchr19:39948380chr19:41313714ENST00000432763+430176_270102.333333333333331088.0SUPT4H1
HgeneSUPT5Hchr19:39948380chr19:41313714ENST00000598725+329176_270102.333333333333331088.0SUPT4H1
HgeneSUPT5Hchr19:39948380chr19:41313714ENST00000599117+531176_270102.333333333333331088.0SUPT4H1


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for SUPT5H-EGLN2


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for SUPT5H-EGLN2


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource