FusionGDB Logo

Home

Download

Statistics

Examples

Help

Contact
Center for Computational Systems Medicine
leaf

Fusion Gene Summary

leaf

Fusion Gene ORF analysis

leaf

Fusion Genomic Features

leaf

Fusion Protein Features

leaf

Fusion Gene Sequence

leaf

Fusion Gene PPI analysis

leaf

Related Drugs

leaf

Related Diseases

Fusion gene:BACH1-OSBPL8 (FusionGDB2 ID:8826)

Fusion Gene Summary for BACH1-OSBPL8

check button Fusion gene summary
Fusion gene informationFusion gene name: BACH1-OSBPL8
Fusion gene ID: 8826
HgeneTgene
Gene symbol

BACH1

OSBPL8

Gene ID

83990

114882

Gene nameBRCA1 interacting protein C-terminal helicase 1oxysterol binding protein like 8
SynonymsBACH1|FANCJ|OFMST120|MSTP120|ORP8|OSBP10
Cytomap

17q23.2

12q21.2

Type of geneprotein-codingprotein-coding
DescriptionFanconi anemia group J proteinATP-dependent RNA helicase BRIP1BRCA1-associated C-terminal helicase 1BRCA1-binding helicase-like protein BACH1BRCA1/BRCA2-associated helicase 1oxysterol-binding protein-related protein 8OSBP-related protein 8
Modification date2020031520200313
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000286800, ENST00000399921, 
ENST00000462262, 		ENST00000552178, 
ENST00000261183, ENST00000393249, 
ENST00000393250, 
Fusion gene scores* DoF score7 X 4 X 7=19613 X 9 X 3=351
# samples 713
** MAII scorelog2(7/196*10)=-1.48542682717024
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(13/351*10)=-1.43295940727611
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: BACH1 [Title/Abstract] AND OSBPL8 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointBACH1(30702014)-OSBPL8(76752591), # samples:2
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneBACH1

GO:0006357

regulation of transcription by RNA polymerase II

14504288

TgeneOSBPL8

GO:0010891

negative regulation of sequestering of triglyceride

23028956

TgeneOSBPL8

GO:0015914

phospholipid transport

26206935

TgeneOSBPL8

GO:0045444

fat cell differentiation

23028956


check buttonFusion gene breakpoints across BACH1 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across OSBPL8 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4SARCTCGA-3B-A9HS-01ABACH1chr21

30702014

-OSBPL8chr12

76752591

-
ChimerDB4SARCTCGA-3B-A9HS-01ABACH1chr21

30702014

+OSBPL8chr12

76752591

-


Top

Fusion Gene ORF analysis for BACH1-OSBPL8

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000286800ENST00000552178BACH1chr21

30702014

+OSBPL8chr12

76752591

-
5CDS-intronENST00000399921ENST00000552178BACH1chr21

30702014

+OSBPL8chr12

76752591

-
In-frameENST00000286800ENST00000261183BACH1chr21

30702014

+OSBPL8chr12

76752591

-
In-frameENST00000286800ENST00000393249BACH1chr21

30702014

+OSBPL8chr12

76752591

-
In-frameENST00000286800ENST00000393250BACH1chr21

30702014

+OSBPL8chr12

76752591

-
In-frameENST00000399921ENST00000261183BACH1chr21

30702014

+OSBPL8chr12

76752591

-
In-frameENST00000399921ENST00000393249BACH1chr21

30702014

+OSBPL8chr12

76752591

-
In-frameENST00000399921ENST00000393250BACH1chr21

30702014

+OSBPL8chr12

76752591

-
intron-3CDSENST00000462262ENST00000261183BACH1chr21

30702014

+OSBPL8chr12

76752591

-
intron-3CDSENST00000462262ENST00000393249BACH1chr21

30702014

+OSBPL8chr12

76752591

-
intron-3CDSENST00000462262ENST00000393250BACH1chr21

30702014

+OSBPL8chr12

76752591

-
intron-intronENST00000462262ENST00000552178BACH1chr21

30702014

+OSBPL8chr12

76752591

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000286800BACH1chr2130702014+ENST00000393249OSBPL8chr1276752591-635319191312260709
ENST00000286800BACH1chr2130702014+ENST00000261183OSBPL8chr1276752591-635019191312260709
ENST00000286800BACH1chr2130702014+ENST00000393250OSBPL8chr1276752591-231419191312260709
ENST00000399921BACH1chr2130702014+ENST00000393249OSBPL8chr1276752591-645320192312360709
ENST00000399921BACH1chr2130702014+ENST00000261183OSBPL8chr1276752591-645020192312360709
ENST00000399921BACH1chr2130702014+ENST00000393250OSBPL8chr1276752591-241420192312360709

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000286800ENST00000393249BACH1chr2130702014+OSBPL8chr1276752591-0.0001299520.99987006
ENST00000286800ENST00000261183BACH1chr2130702014+OSBPL8chr1276752591-0.0001294360.99987054
ENST00000286800ENST00000393250BACH1chr2130702014+OSBPL8chr1276752591-0.0013973880.99860257
ENST00000399921ENST00000393249BACH1chr2130702014+OSBPL8chr1276752591-0.000132260.9998677
ENST00000399921ENST00000261183BACH1chr2130702014+OSBPL8chr1276752591-0.0001317640.9998683
ENST00000399921ENST00000393250BACH1chr2130702014+OSBPL8chr1276752591-0.0012282540.9987717

Top

Fusion Genomic Features for BACH1-OSBPL8


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

Top

Fusion Protein Features for BACH1-OSBPL8


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr21:30702014/chr12:76752591)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneBACH1chr21:30702014chr12:76752591ENST00000286800+4534_100592737.0DomainBTB
HgeneBACH1chr21:30702014chr12:76752591ENST00000399921+4534_100592737.0DomainBTB
HgeneBACH1chr21:30702014chr12:76752591ENST00000286800+45562_578592737.0RegionBasic motif
HgeneBACH1chr21:30702014chr12:76752591ENST00000286800+45582_589592737.0RegionLeucine-zipper
HgeneBACH1chr21:30702014chr12:76752591ENST00000399921+45562_578592737.0RegionBasic motif
HgeneBACH1chr21:30702014chr12:76752591ENST00000399921+45582_589592737.0RegionLeucine-zipper
TgeneOSBPL8chr21:30702014chr12:76752591ENST000002611832024871_888776890.0TransmembraneHelical
TgeneOSBPL8chr21:30702014chr12:76752591ENST000003932492226871_888734848.0TransmembraneHelical
TgeneOSBPL8chr21:30702014chr12:76752591ENST000003932501923871_888734848.0TransmembraneHelical

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneBACH1chr21:30702014chr12:76752591ENST00000286800+45557_620592737.0DomainbZIP
HgeneBACH1chr21:30702014chr12:76752591ENST00000399921+45557_620592737.0DomainbZIP
TgeneOSBPL8chr21:30702014chr12:76752591ENST000002611832024148_265776890.0DomainPH
TgeneOSBPL8chr21:30702014chr12:76752591ENST000003932492226148_265734848.0DomainPH
TgeneOSBPL8chr21:30702014chr12:76752591ENST000003932501923148_265734848.0DomainPH
TgeneOSBPL8chr21:30702014chr12:76752591ENST000002611832024420_425776890.0RegionPhosphatidylserine binding
TgeneOSBPL8chr21:30702014chr12:76752591ENST000002611832024482_485776890.0RegionPhosphatidylinositol 4-phosphate binding
TgeneOSBPL8chr21:30702014chr12:76752591ENST000003932492226420_425734848.0RegionPhosphatidylserine binding
TgeneOSBPL8chr21:30702014chr12:76752591ENST000003932492226482_485734848.0RegionPhosphatidylinositol 4-phosphate binding
TgeneOSBPL8chr21:30702014chr12:76752591ENST000003932501923420_425734848.0RegionPhosphatidylserine binding
TgeneOSBPL8chr21:30702014chr12:76752591ENST000003932501923482_485734848.0RegionPhosphatidylinositol 4-phosphate binding


Top

Fusion Gene Sequence for BACH1-OSBPL8


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>8826_8826_1_BACH1-OSBPL8_BACH1_chr21_30702014_ENST00000286800_OSBPL8_chr12_76752591_ENST00000261183_length(transcript)=6350nt_BP=1919nt
GAGTGAGTCACCTGACCGCTGCCCTCGCCGCCCGCCGGGCGCTCTCGCTTCAGTCAGTCGGGCCGCGCCGCGCCTCAGCTCTGGTTGATG
ATAATTAGAAGCATGCTTTCCACTGAACTTCCCGACAACATTTGTTATGCAGAATGTCTCTGAGTGAGAACTCGGTTTTTGCCTATGAAT
CTTCTGTGCATAGCACCAATGTTTTACTCAGCCTTAATGACCAGCGGAAGAAAGATGTGCTGTGCGATGTCACCATCTTTGTGGAGGGAC
AGCGGTTCCGCGCTCACCGGTCCGTGCTGGCGGCATGCAGCAGTTACTTCCACTCAAGAATCGTAGGCCAGGCTGATGGAGAGCTGAACA
TTACTCTTCCAGAAGAGGTGACAGTTAAAGGATTTGAACCTTTAATTCAGTTTGCCTACACTGCTAAACTGATTTTAAGTAAAGAGAATG
TGGATGAAGTGTGCAAATGTGTGGAGTTTTTAAGTGTACATAATATTGAGGAATCCTGCTTTCAGTTTCTGAAATTTAAGTTTTTGGACT
CCACTGCAGACCAGCAAGAATGCCCAAGAAAAAAATGCTTTTCATCACACTGTCAGAAAACAGACCTTAAACTTTCACTTTTGGACCAGA
GGGATCTAGAAACTGATGAAGTGGAGGAATTTCTGGAAAATAAAAATGTTCAGACTCCTCAGTGTAAACTCCGCAGGTATCAAGGAAATG
CAAAAGCCTCACCTCCTCTACAAGACAGTGCCAGTCAGACATATGAGTCCATGTGCTTAGAGAAGGATGCTGCTCTGGCCTTGCCTTCTT
TATGCCCCAAATACAGAAAATTCCAAAAAGCATTTGGAACTGACAGAGTCCGTACTGGGGAATCTAGTGTCAAAGACATTCATGCTTCTG
TTCAGCCAAATGAAAGGTCTGAAAATGAATGCCTGGGAGGAGTCCCGGAGTGTAGAGATTTGCAGGTGATGTTAAAATGTGACGAAAGTA
AATTAGCAATGGAACCTGAAGAAACGAAGAAAGATCCTGCTTCTCAGTGCCCAACTGAAAAATCAGAAGTGACTCCTTTCCCCCACAATT
CTTCCATAGACCCTCATGGACTTTATTCTTTGTCTCTTTTACACACATATGACCAATATGGTGACTTGAATTTTGCTGGTATGCAAAACA
CAACAGTGTTAACAGAAAAGCCTTTGTCAGGTACAGACGTCCAAGAAAAAACATTTGGTGAAAGTCAGGATTTACCTTTGAAATCCGACT
TGGGCACCAGGGAAGATAGTAGTGTTGCATCTAGTGATAGGAGTAGTGTGGAGCGAGAAGTGGCAGAACACCTAGCAAAAGGCTTCTGGA
GTGACATTTGCAGCACGGACACTCCTTGCCAAATGCAGTTATCACCTGCTGTGGCCAAAGATGGCTCAGAACAGATCTCACAGAAACGGT
CTGAGTGTCCGTGGTTAGGTATCAGGATTAGTGAGAGCCCAGAACCAGGTCAAAGGACTTTCACAACATTAAGTTCTGTCAACTGCCCTT
TTATAAGTACTCTGAGTACTGAAGGCTGTTCAAGCAATTTGGAAATTGGAAACGATGATTATGTTTCAGAACCCCAGCAAGAACCTTGCC
CATATGCTTGTGTCATTAGCTTGGGAGACGACTCTGAGACGGACACCGAAGGAGACAGTGAATCCTGTTCAGCCAGAGAACAAGAATGTG
AGGTAAAACTGCCATTCAATGCACAACGGATAATTTCACTGTCTCGAAATGATTTTCAGTCCTTGTTGAAAATGCACAAGCTTACTCCAG
AACAGCTGGATTGTATCCATGATATTCGAAGAAGAAGTAAAAACAGAATTGCTGCACAGCGCTGTCGCAAGAGAAAACTTGACTGTATAC
AGAATCTTGAATCAGAAATTGAGAAGCTGGTTAGCGTCCCCAAAATGAAACATAAGCCAACCAGGCAACAGAAGAAAGTAGCAAAAGGCT
ATTCCTCCCCAGAACCTGACATTCAAGACTCCTCTGGAAGTGAAGCTCAATCAGTAAAACCAAGTACAAGAAGAAAGAAAGGAATAGAAC
TGGGAGACATTCAGAGTTCCATCGAATCTATAAAACAAACACAGGAAGAAATTAAAAGAAATATTATGGCTCTTCGAAATCATTTAGTTT
CAAGCACACCGGCCACGGATTATTTTCTGCAACAAAAAGACTACTTCATCATTTTCCTCCTGATTTTGCTTCAAGTCATAATAAACTTCA
TGTTCAAGTAGAAGTTCTCTACCATTGAATCAGTGAACTAGAAAGATCTGATTTGGCCTGGGACCAGTGTTCAAGTTGGTTTGGTCTTTA
TTAAAAATCACAATATTCCGAAAACAAAAAAACCTAGGAGATAAATGTAGAGGTATTGACTTTTCGTATCTTTTATCTTCACACTGAAAC
AAGAGCTATCCTATTTGATTATTAAAGTGAGCTATGTGTTAAGTGCCAGGACATTTCTAGCTTTTGTGAGAATGTGTCTACATATGAGTA
TAATAAACCCACATGTATACACAATTGTCTCTTATGTACTCCTACCTGACAGTAGTCTTTGTATTCTATAGTATGTTCTGAGATATAATG
TTAACATTGTTCATAACAAAAAATGCTATCAATCTTATAAATATATGTAATCTATTTTCTTCATAAAACAGGCACAAAAGTTTTATCAGT
AAGGAATTACAGATTGAGAAATGATGGAATAATAGACATAATTAATTCAATACACTACTGTTAAAATCATTTGCAAAGCACTCAGCTCAA
TTATCTTCTTAGAAAGAAAGAAAAAGTATGAATGGTCAAAATGAATACATCGAGAGAGATAAATGGCAAATTGCTTTTTTAAAAGTTTAC
ATAAGTTTTTTTTAACCCCTAGAATTTAATATTTGTAGATGCAGGTAAATATATATACTTACGTGTATATCAGTATAAAAACACTGGTGT
GCAATTAATTGGATTGATTATAATACCACCTTAAGCACTTGCTGAAAAAAGTGTGGTCAAAATTGATTGCTGTCCTTTTGTCTTATTTTT
GTTTTTCTTAAGTCAGCTGGTTCATAACATAGGCCAAATTCTAGAGATGTTTATAGAGCATTTGAAGTGCTGATAATTTATGTTTTTTCA
TTATGAAAACTTATTTTAGCTTTAGACTCCAGTGTGTTCAGTGAATAAGTAGAATATAAAAAAATATAACCAGTATTTTACTTCAAAAGC
CAAAAAGAGGCAATAAGAAAAGACACTTTGTGGTGGCCTTTATGTGTGCATTAAAATTGGTTTCTGTAAAACGTGTAATAAGTTGAGTAT
CTACGAAGAGTATCAAGTTCTGAAGTTTAATTTTTTTATTATCCTCCTCTCTTCTTAGTAACTTCTTTCTGTGGCAAAACCACAATTCTT
TAAGATTCCTATTGTTCAGGCTAAGGCAAATTTTTTTGTTTGTTTCTTCAGTTTAATATTTTGATTTTGTGTTTTTACGTAAATATTTAT
ATTCCTTGAAAGCAATTTTTGCCAAGGTAGTTCAGTTTAGGAATATGTTGTTCTAAAATATGTCTTAGAATCCTGAAAGCATAGATTTTG
AAATGTTTTTTTAATGAAAATGAAGGTCAGAGAGAATAATTGCCCTGACCACATTTGCCTTTCAGTAGGAGGAGGCTGTGAAATAGTAAA
ATTATAATCGTTTATGCCATGATAAATACAAGATTGGTAAATAAATACATTGATTGGTAAATTATGAGAATCAAAATGATAAAAAGAGCC
TGCTTTTTTCCCTAACCAATATAGCTATCTTAAGTATCCTTAGGTTTCTGTGAAGAACCATTTCCCATGTTTTCTTGGCAAAATAATGCT
GTATTCCATATGTACATGTGAAATGATGTTTTAAATTGATAAAAGCTTAAATAAGATCTACCTATACCCAGTATTTTCATGATATTAGAA
CAAATGGGTTTTTGGTTATATTTTATATTTGTCAATATAATTTTTGTATTCACATTCTGTTACACTCTGCCTATTCATTGATATATGATA
TTCTGTAAATATTGTACAATTTGATCTTTTTTATGGTTTAAATTAGTTAATTACATACAAATTGATTGGCTTATCACAAAAATCATTTCA
TCAGTAAACCTTGTTAACATTTTGTACTGGTGACCCACCTCTTAGGACTTTGGTCTTATCCACGTGTATGTTGTTTTCATTTGGTCCAAA
TAATATTTTATTTGTATGGGTATCTTCTAAGACTAAATAGGTAGTTGTGTTCTTTATTTTTAAAATTTCTTTTTAGAGCAAATGTTATGG
GTTCTTACCCAAAGAGTCAAAAACTATTTCTTAAGAAAGAGCAGAGTTATTCATGACTGTTCTTTATACACTAAAAGCATGCATCTAATC
TAATAGTCCTCTTATTATGCTTTTAGTTGTATGAGTCTCTTTCTATGAACTGAACACAAAACTCAGGAATTGGTGGCTTAATTTTAGATC
AGTGCTTGTACTAGGCTTAGTTATATGAATCTTTATAACACATAATTACTAACTTTGTAGCCATATATGTAATTGACTTTGAATGTTATT
TACCTGAAATTAATCTTCCTTCACACATGGACCGTAAACGGTTCCCAGTTGTCTGAGAGCCTCATGAGGGTTTCTAGGATTTATGACCTT
ATGACCAGTTTTTTTCATTTACCAAGATTTTATTTTCCTACATGAAAATTTAATTGAGTAATAATTATTCACATGTGCATTTTCTTTTTA
GCTGTTAAATGTACTATGCCATCATCCACCATTTAGTAAAATGTAGCTGGCCCAGGACATGTAAAAAAAAAAAAAAAACAACAACAATAA
ATAGGGCATGTGAAATGTTAAGTTACAGCAATAGATATTTTATTTGTATTTCATGTTAGTACTTTTTTGTTTTATATCACTTATAAAGGT
ACAGTGTACTCTTTGTCACAGCTCAGTTGGTAACCGCATTCCATTGAAAAGTTGGCCTTGTAAAATACAACTCTCATTTAATATTCATGC
TTTTGTGCCTTTAAGAAAATATTTTTTGTCATTTTTTGTGTTACAGAACTATAATGTGATTCAAGGTGTTTATAGGCTTGTCATAAAAGG
GTCATTTCTGTGTGTTACTTTCTTTTTATATAGCTATAGTATATTTAAACAATAATACTATCTTTTATAGGGGTTTGTCTATTTACCTAT
TCTTTACTCAGACATTGATGTAGACTTGTCAGATTATTCTGAGTATTGTTAACAGTGCCTTTTCGATGGAATCACACTTTTTGGCTGTCA
CCTTGTGCCATATACACACAAAATTTTGTGGAAGGCAGTTTTAACTTTCTGAAGAATATCTGTCAAAATTTAAGAAAACAAATGTATAAA
ATTCCATTTTTTCCAGTGTTTAGCATTTCTAGTAAGCAGTGAGGTTGTTTGACATACAGTGATGATGGCATTATTGATAAGCCATACATG
AGACTGCAGATTATATTGAATCATATTAAATGTACAGAAATAAAATATTAGATTTATATCAAATTTTCCAATTTGAACCAGTGGGGAAAA
TCCCACAGAAATCAGTAAGTTTACATTTCAATTTCTATCTTATTTGACTAAGTGGAAAGAGATTCTTTAAAATGTATAACCTGCCATTAT
GTAATTTGGTTTCATTTTATTCTACCTGTTGTGTGAGTTTAGTATATTTAATTTACTTTTTGTTACTCTTTACATACTGTTTATTTTTGT
TAGTTTTTAATTGAAGATGGACTGTTGAAATTGTATAGGACCAGTGTCTTATTAATATGATTAATATATTTAGAAGAGCCACGTGAAACC
CATGACAAAATGAATGTGAATATTCTTTCTAAAAATTTAGAAAATGTTATCTTTTTGCATTTATTATGTAAAACTGTTTTACAGTATCAA
AATTTTTCACTTAAAGAAAAAAAATGCCATGAAACATTTGAACTGATGAGCCACAGAACTTCAGTTGAAATTTTTTTCACTTTTTAGCAT
GCTAAATATACATCTGAGTTTAAATGTTCTGTTTAATGGCCATTCATAAATTCAAGCACTACCACTGGTCAGTTTTGTGTGATAGAATAA
AAATATGTTACCTGCAGTGTAAGTACAGCACACTGTCAAATTCTTTTCCTTAAGGTGCACAGTAAATGTACAGATAGTTATAGGCCACTG
TTTTGTAATGTAGTACATTTCTAATCTATTATTCCTAACCTATTATAACTGTTTGCAGAAAGAAAAGAATTTTTCTAATAATCTGTAAAA

>8826_8826_1_BACH1-OSBPL8_BACH1_chr21_30702014_ENST00000286800_OSBPL8_chr12_76752591_ENST00000261183_length(amino acids)=709AA_BP=596
MLCRMSLSENSVFAYESSVHSTNVLLSLNDQRKKDVLCDVTIFVEGQRFRAHRSVLAACSSYFHSRIVGQADGELNITLPEEVTVKGFEP
LIQFAYTAKLILSKENVDEVCKCVEFLSVHNIEESCFQFLKFKFLDSTADQQECPRKKCFSSHCQKTDLKLSLLDQRDLETDEVEEFLEN
KNVQTPQCKLRRYQGNAKASPPLQDSASQTYESMCLEKDAALALPSLCPKYRKFQKAFGTDRVRTGESSVKDIHASVQPNERSENECLGG
VPECRDLQVMLKCDESKLAMEPEETKKDPASQCPTEKSEVTPFPHNSSIDPHGLYSLSLLHTYDQYGDLNFAGMQNTTVLTEKPLSGTDV
QEKTFGESQDLPLKSDLGTREDSSVASSDRSSVEREVAEHLAKGFWSDICSTDTPCQMQLSPAVAKDGSEQISQKRSECPWLGIRISESP
EPGQRTFTTLSSVNCPFISTLSTEGCSSNLEIGNDDYVSEPQQEPCPYACVISLGDDSETDTEGDSESCSAREQECEVKLPFNAQRIISL
SRNDFQSLLKMHKLTPEQLDCIHDIRRRSKNRIAAQRCRKRKLDCIQNLESEIEKLVSVPKMKHKPTRQQKKVAKGYSSPEPDIQDSSGS

--------------------------------------------------------------
>8826_8826_2_BACH1-OSBPL8_BACH1_chr21_30702014_ENST00000286800_OSBPL8_chr12_76752591_ENST00000393249_length(transcript)=6353nt_BP=1919nt
GAGTGAGTCACCTGACCGCTGCCCTCGCCGCCCGCCGGGCGCTCTCGCTTCAGTCAGTCGGGCCGCGCCGCGCCTCAGCTCTGGTTGATG
ATAATTAGAAGCATGCTTTCCACTGAACTTCCCGACAACATTTGTTATGCAGAATGTCTCTGAGTGAGAACTCGGTTTTTGCCTATGAAT
CTTCTGTGCATAGCACCAATGTTTTACTCAGCCTTAATGACCAGCGGAAGAAAGATGTGCTGTGCGATGTCACCATCTTTGTGGAGGGAC
AGCGGTTCCGCGCTCACCGGTCCGTGCTGGCGGCATGCAGCAGTTACTTCCACTCAAGAATCGTAGGCCAGGCTGATGGAGAGCTGAACA
TTACTCTTCCAGAAGAGGTGACAGTTAAAGGATTTGAACCTTTAATTCAGTTTGCCTACACTGCTAAACTGATTTTAAGTAAAGAGAATG
TGGATGAAGTGTGCAAATGTGTGGAGTTTTTAAGTGTACATAATATTGAGGAATCCTGCTTTCAGTTTCTGAAATTTAAGTTTTTGGACT
CCACTGCAGACCAGCAAGAATGCCCAAGAAAAAAATGCTTTTCATCACACTGTCAGAAAACAGACCTTAAACTTTCACTTTTGGACCAGA
GGGATCTAGAAACTGATGAAGTGGAGGAATTTCTGGAAAATAAAAATGTTCAGACTCCTCAGTGTAAACTCCGCAGGTATCAAGGAAATG
CAAAAGCCTCACCTCCTCTACAAGACAGTGCCAGTCAGACATATGAGTCCATGTGCTTAGAGAAGGATGCTGCTCTGGCCTTGCCTTCTT
TATGCCCCAAATACAGAAAATTCCAAAAAGCATTTGGAACTGACAGAGTCCGTACTGGGGAATCTAGTGTCAAAGACATTCATGCTTCTG
TTCAGCCAAATGAAAGGTCTGAAAATGAATGCCTGGGAGGAGTCCCGGAGTGTAGAGATTTGCAGGTGATGTTAAAATGTGACGAAAGTA
AATTAGCAATGGAACCTGAAGAAACGAAGAAAGATCCTGCTTCTCAGTGCCCAACTGAAAAATCAGAAGTGACTCCTTTCCCCCACAATT
CTTCCATAGACCCTCATGGACTTTATTCTTTGTCTCTTTTACACACATATGACCAATATGGTGACTTGAATTTTGCTGGTATGCAAAACA
CAACAGTGTTAACAGAAAAGCCTTTGTCAGGTACAGACGTCCAAGAAAAAACATTTGGTGAAAGTCAGGATTTACCTTTGAAATCCGACT
TGGGCACCAGGGAAGATAGTAGTGTTGCATCTAGTGATAGGAGTAGTGTGGAGCGAGAAGTGGCAGAACACCTAGCAAAAGGCTTCTGGA
GTGACATTTGCAGCACGGACACTCCTTGCCAAATGCAGTTATCACCTGCTGTGGCCAAAGATGGCTCAGAACAGATCTCACAGAAACGGT
CTGAGTGTCCGTGGTTAGGTATCAGGATTAGTGAGAGCCCAGAACCAGGTCAAAGGACTTTCACAACATTAAGTTCTGTCAACTGCCCTT
TTATAAGTACTCTGAGTACTGAAGGCTGTTCAAGCAATTTGGAAATTGGAAACGATGATTATGTTTCAGAACCCCAGCAAGAACCTTGCC
CATATGCTTGTGTCATTAGCTTGGGAGACGACTCTGAGACGGACACCGAAGGAGACAGTGAATCCTGTTCAGCCAGAGAACAAGAATGTG
AGGTAAAACTGCCATTCAATGCACAACGGATAATTTCACTGTCTCGAAATGATTTTCAGTCCTTGTTGAAAATGCACAAGCTTACTCCAG
AACAGCTGGATTGTATCCATGATATTCGAAGAAGAAGTAAAAACAGAATTGCTGCACAGCGCTGTCGCAAGAGAAAACTTGACTGTATAC
AGAATCTTGAATCAGAAATTGAGAAGCTGGTTAGCGTCCCCAAAATGAAACATAAGCCAACCAGGCAACAGAAGAAAGTAGCAAAAGGCT
ATTCCTCCCCAGAACCTGACATTCAAGACTCCTCTGGAAGTGAAGCTCAATCAGTAAAACCAAGTACAAGAAGAAAGAAAGGAATAGAAC
TGGGAGACATTCAGAGTTCCATCGAATCTATAAAACAAACACAGGAAGAAATTAAAAGAAATATTATGGCTCTTCGAAATCATTTAGTTT
CAAGCACACCGGCCACGGATTATTTTCTGCAACAAAAAGACTACTTCATCATTTTCCTCCTGATTTTGCTTCAAGTCATAATAAACTTCA
TGTTCAAGTAGAAGTTCTCTACCATTGAATCAGTGAACTAGAAAGATCTGATTTGGCCTGGGACCAGTGTTCAAGTTGGTTTGGTCTTTA
TTAAAAATCACAATATTCCGAAAACAAAAAAACCTAGGAGATAAATGTAGAGGTATTGACTTTTCGTATCTTTTATCTTCACACTGAAAC
AAGAGCTATCCTATTTGATTATTAAAGTGAGCTATGTGTTAAGTGCCAGGACATTTCTAGCTTTTGTGAGAATGTGTCTACATATGAGTA
TAATAAACCCACATGTATACACAATTGTCTCTTATGTACTCCTACCTGACAGTAGTCTTTGTATTCTATAGTATGTTCTGAGATATAATG
TTAACATTGTTCATAACAAAAAATGCTATCAATCTTATAAATATATGTAATCTATTTTCTTCATAAAACAGGCACAAAAGTTTTATCAGT
AAGGAATTACAGATTGAGAAATGATGGAATAATAGACATAATTAATTCAATACACTACTGTTAAAATCATTTGCAAAGCACTCAGCTCAA
TTATCTTCTTAGAAAGAAAGAAAAAGTATGAATGGTCAAAATGAATACATCGAGAGAGATAAATGGCAAATTGCTTTTTTAAAAGTTTAC
ATAAGTTTTTTTTAACCCCTAGAATTTAATATTTGTAGATGCAGGTAAATATATATACTTACGTGTATATCAGTATAAAAACACTGGTGT
GCAATTAATTGGATTGATTATAATACCACCTTAAGCACTTGCTGAAAAAAGTGTGGTCAAAATTGATTGCTGTCCTTTTGTCTTATTTTT
GTTTTTCTTAAGTCAGCTGGTTCATAACATAGGCCAAATTCTAGAGATGTTTATAGAGCATTTGAAGTGCTGATAATTTATGTTTTTTCA
TTATGAAAACTTATTTTAGCTTTAGACTCCAGTGTGTTCAGTGAATAAGTAGAATATAAAAAAATATAACCAGTATTTTACTTCAAAAGC
CAAAAAGAGGCAATAAGAAAAGACACTTTGTGGTGGCCTTTATGTGTGCATTAAAATTGGTTTCTGTAAAACGTGTAATAAGTTGAGTAT
CTACGAAGAGTATCAAGTTCTGAAGTTTAATTTTTTTATTATCCTCCTCTCTTCTTAGTAACTTCTTTCTGTGGCAAAACCACAATTCTT
TAAGATTCCTATTGTTCAGGCTAAGGCAAATTTTTTTGTTTGTTTCTTCAGTTTAATATTTTGATTTTGTGTTTTTACGTAAATATTTAT
ATTCCTTGAAAGCAATTTTTGCCAAGGTAGTTCAGTTTAGGAATATGTTGTTCTAAAATATGTCTTAGAATCCTGAAAGCATAGATTTTG
AAATGTTTTTTTAATGAAAATGAAGGTCAGAGAGAATAATTGCCCTGACCACATTTGCCTTTCAGTAGGAGGAGGCTGTGAAATAGTAAA
ATTATAATCGTTTATGCCATGATAAATACAAGATTGGTAAATAAATACATTGATTGGTAAATTATGAGAATCAAAATGATAAAAAGAGCC
TGCTTTTTTCCCTAACCAATATAGCTATCTTAAGTATCCTTAGGTTTCTGTGAAGAACCATTTCCCATGTTTTCTTGGCAAAATAATGCT
GTATTCCATATGTACATGTGAAATGATGTTTTAAATTGATAAAAGCTTAAATAAGATCTACCTATACCCAGTATTTTCATGATATTAGAA
CAAATGGGTTTTTGGTTATATTTTATATTTGTCAATATAATTTTTGTATTCACATTCTGTTACACTCTGCCTATTCATTGATATATGATA
TTCTGTAAATATTGTACAATTTGATCTTTTTTATGGTTTAAATTAGTTAATTACATACAAATTGATTGGCTTATCACAAAAATCATTTCA
TCAGTAAACCTTGTTAACATTTTGTACTGGTGACCCACCTCTTAGGACTTTGGTCTTATCCACGTGTATGTTGTTTTCATTTGGTCCAAA
TAATATTTTATTTGTATGGGTATCTTCTAAGACTAAATAGGTAGTTGTGTTCTTTATTTTTAAAATTTCTTTTTAGAGCAAATGTTATGG
GTTCTTACCCAAAGAGTCAAAAACTATTTCTTAAGAAAGAGCAGAGTTATTCATGACTGTTCTTTATACACTAAAAGCATGCATCTAATC
TAATAGTCCTCTTATTATGCTTTTAGTTGTATGAGTCTCTTTCTATGAACTGAACACAAAACTCAGGAATTGGTGGCTTAATTTTAGATC
AGTGCTTGTACTAGGCTTAGTTATATGAATCTTTATAACACATAATTACTAACTTTGTAGCCATATATGTAATTGACTTTGAATGTTATT
TACCTGAAATTAATCTTCCTTCACACATGGACCGTAAACGGTTCCCAGTTGTCTGAGAGCCTCATGAGGGTTTCTAGGATTTATGACCTT
ATGACCAGTTTTTTTCATTTACCAAGATTTTATTTTCCTACATGAAAATTTAATTGAGTAATAATTATTCACATGTGCATTTTCTTTTTA
GCTGTTAAATGTACTATGCCATCATCCACCATTTAGTAAAATGTAGCTGGCCCAGGACATGTAAAAAAAAAAAAAAAACAACAACAATAA
ATAGGGCATGTGAAATGTTAAGTTACAGCAATAGATATTTTATTTGTATTTCATGTTAGTACTTTTTTGTTTTATATCACTTATAAAGGT
ACAGTGTACTCTTTGTCACAGCTCAGTTGGTAACCGCATTCCATTGAAAAGTTGGCCTTGTAAAATACAACTCTCATTTAATATTCATGC
TTTTGTGCCTTTAAGAAAATATTTTTTGTCATTTTTTGTGTTACAGAACTATAATGTGATTCAAGGTGTTTATAGGCTTGTCATAAAAGG
GTCATTTCTGTGTGTTACTTTCTTTTTATATAGCTATAGTATATTTAAACAATAATACTATCTTTTATAGGGGTTTGTCTATTTACCTAT
TCTTTACTCAGACATTGATGTAGACTTGTCAGATTATTCTGAGTATTGTTAACAGTGCCTTTTCGATGGAATCACACTTTTTGGCTGTCA
CCTTGTGCCATATACACACAAAATTTTGTGGAAGGCAGTTTTAACTTTCTGAAGAATATCTGTCAAAATTTAAGAAAACAAATGTATAAA
ATTCCATTTTTTCCAGTGTTTAGCATTTCTAGTAAGCAGTGAGGTTGTTTGACATACAGTGATGATGGCATTATTGATAAGCCATACATG
AGACTGCAGATTATATTGAATCATATTAAATGTACAGAAATAAAATATTAGATTTATATCAAATTTTCCAATTTGAACCAGTGGGGAAAA
TCCCACAGAAATCAGTAAGTTTACATTTCAATTTCTATCTTATTTGACTAAGTGGAAAGAGATTCTTTAAAATGTATAACCTGCCATTAT
GTAATTTGGTTTCATTTTATTCTACCTGTTGTGTGAGTTTAGTATATTTAATTTACTTTTTGTTACTCTTTACATACTGTTTATTTTTGT
TAGTTTTTAATTGAAGATGGACTGTTGAAATTGTATAGGACCAGTGTCTTATTAATATGATTAATATATTTAGAAGAGCCACGTGAAACC
CATGACAAAATGAATGTGAATATTCTTTCTAAAAATTTAGAAAATGTTATCTTTTTGCATTTATTATGTAAAACTGTTTTACAGTATCAA
AATTTTTCACTTAAAGAAAAAAAATGCCATGAAACATTTGAACTGATGAGCCACAGAACTTCAGTTGAAATTTTTTTCACTTTTTAGCAT
GCTAAATATACATCTGAGTTTAAATGTTCTGTTTAATGGCCATTCATAAATTCAAGCACTACCACTGGTCAGTTTTGTGTGATAGAATAA
AAATATGTTACCTGCAGTGTAAGTACAGCACACTGTCAAATTCTTTTCCTTAAGGTGCACAGTAAATGTACAGATAGTTATAGGCCACTG
TTTTGTAATGTAGTACATTTCTAATCTATTATTCCTAACCTATTATAACTGTTTGCAGAAAGAAAAGAATTTTTCTAATAATCTGTAAAA

>8826_8826_2_BACH1-OSBPL8_BACH1_chr21_30702014_ENST00000286800_OSBPL8_chr12_76752591_ENST00000393249_length(amino acids)=709AA_BP=596
MLCRMSLSENSVFAYESSVHSTNVLLSLNDQRKKDVLCDVTIFVEGQRFRAHRSVLAACSSYFHSRIVGQADGELNITLPEEVTVKGFEP
LIQFAYTAKLILSKENVDEVCKCVEFLSVHNIEESCFQFLKFKFLDSTADQQECPRKKCFSSHCQKTDLKLSLLDQRDLETDEVEEFLEN
KNVQTPQCKLRRYQGNAKASPPLQDSASQTYESMCLEKDAALALPSLCPKYRKFQKAFGTDRVRTGESSVKDIHASVQPNERSENECLGG
VPECRDLQVMLKCDESKLAMEPEETKKDPASQCPTEKSEVTPFPHNSSIDPHGLYSLSLLHTYDQYGDLNFAGMQNTTVLTEKPLSGTDV
QEKTFGESQDLPLKSDLGTREDSSVASSDRSSVEREVAEHLAKGFWSDICSTDTPCQMQLSPAVAKDGSEQISQKRSECPWLGIRISESP
EPGQRTFTTLSSVNCPFISTLSTEGCSSNLEIGNDDYVSEPQQEPCPYACVISLGDDSETDTEGDSESCSAREQECEVKLPFNAQRIISL
SRNDFQSLLKMHKLTPEQLDCIHDIRRRSKNRIAAQRCRKRKLDCIQNLESEIEKLVSVPKMKHKPTRQQKKVAKGYSSPEPDIQDSSGS

--------------------------------------------------------------
>8826_8826_3_BACH1-OSBPL8_BACH1_chr21_30702014_ENST00000286800_OSBPL8_chr12_76752591_ENST00000393250_length(transcript)=2314nt_BP=1919nt
GAGTGAGTCACCTGACCGCTGCCCTCGCCGCCCGCCGGGCGCTCTCGCTTCAGTCAGTCGGGCCGCGCCGCGCCTCAGCTCTGGTTGATG
ATAATTAGAAGCATGCTTTCCACTGAACTTCCCGACAACATTTGTTATGCAGAATGTCTCTGAGTGAGAACTCGGTTTTTGCCTATGAAT
CTTCTGTGCATAGCACCAATGTTTTACTCAGCCTTAATGACCAGCGGAAGAAAGATGTGCTGTGCGATGTCACCATCTTTGTGGAGGGAC
AGCGGTTCCGCGCTCACCGGTCCGTGCTGGCGGCATGCAGCAGTTACTTCCACTCAAGAATCGTAGGCCAGGCTGATGGAGAGCTGAACA
TTACTCTTCCAGAAGAGGTGACAGTTAAAGGATTTGAACCTTTAATTCAGTTTGCCTACACTGCTAAACTGATTTTAAGTAAAGAGAATG
TGGATGAAGTGTGCAAATGTGTGGAGTTTTTAAGTGTACATAATATTGAGGAATCCTGCTTTCAGTTTCTGAAATTTAAGTTTTTGGACT
CCACTGCAGACCAGCAAGAATGCCCAAGAAAAAAATGCTTTTCATCACACTGTCAGAAAACAGACCTTAAACTTTCACTTTTGGACCAGA
GGGATCTAGAAACTGATGAAGTGGAGGAATTTCTGGAAAATAAAAATGTTCAGACTCCTCAGTGTAAACTCCGCAGGTATCAAGGAAATG
CAAAAGCCTCACCTCCTCTACAAGACAGTGCCAGTCAGACATATGAGTCCATGTGCTTAGAGAAGGATGCTGCTCTGGCCTTGCCTTCTT
TATGCCCCAAATACAGAAAATTCCAAAAAGCATTTGGAACTGACAGAGTCCGTACTGGGGAATCTAGTGTCAAAGACATTCATGCTTCTG
TTCAGCCAAATGAAAGGTCTGAAAATGAATGCCTGGGAGGAGTCCCGGAGTGTAGAGATTTGCAGGTGATGTTAAAATGTGACGAAAGTA
AATTAGCAATGGAACCTGAAGAAACGAAGAAAGATCCTGCTTCTCAGTGCCCAACTGAAAAATCAGAAGTGACTCCTTTCCCCCACAATT
CTTCCATAGACCCTCATGGACTTTATTCTTTGTCTCTTTTACACACATATGACCAATATGGTGACTTGAATTTTGCTGGTATGCAAAACA
CAACAGTGTTAACAGAAAAGCCTTTGTCAGGTACAGACGTCCAAGAAAAAACATTTGGTGAAAGTCAGGATTTACCTTTGAAATCCGACT
TGGGCACCAGGGAAGATAGTAGTGTTGCATCTAGTGATAGGAGTAGTGTGGAGCGAGAAGTGGCAGAACACCTAGCAAAAGGCTTCTGGA
GTGACATTTGCAGCACGGACACTCCTTGCCAAATGCAGTTATCACCTGCTGTGGCCAAAGATGGCTCAGAACAGATCTCACAGAAACGGT
CTGAGTGTCCGTGGTTAGGTATCAGGATTAGTGAGAGCCCAGAACCAGGTCAAAGGACTTTCACAACATTAAGTTCTGTCAACTGCCCTT
TTATAAGTACTCTGAGTACTGAAGGCTGTTCAAGCAATTTGGAAATTGGAAACGATGATTATGTTTCAGAACCCCAGCAAGAACCTTGCC
CATATGCTTGTGTCATTAGCTTGGGAGACGACTCTGAGACGGACACCGAAGGAGACAGTGAATCCTGTTCAGCCAGAGAACAAGAATGTG
AGGTAAAACTGCCATTCAATGCACAACGGATAATTTCACTGTCTCGAAATGATTTTCAGTCCTTGTTGAAAATGCACAAGCTTACTCCAG
AACAGCTGGATTGTATCCATGATATTCGAAGAAGAAGTAAAAACAGAATTGCTGCACAGCGCTGTCGCAAGAGAAAACTTGACTGTATAC
AGAATCTTGAATCAGAAATTGAGAAGCTGGTTAGCGTCCCCAAAATGAAACATAAGCCAACCAGGCAACAGAAGAAAGTAGCAAAAGGCT
ATTCCTCCCCAGAACCTGACATTCAAGACTCCTCTGGAAGTGAAGCTCAATCAGTAAAACCAAGTACAAGAAGAAAGAAAGGAATAGAAC
TGGGAGACATTCAGAGTTCCATCGAATCTATAAAACAAACACAGGAAGAAATTAAAAGAAATATTATGGCTCTTCGAAATCATTTAGTTT
CAAGCACACCGGCCACGGATTATTTTCTGCAACAAAAAGACTACTTCATCATTTTCCTCCTGATTTTGCTTCAAGTCATAATAAACTTCA

>8826_8826_3_BACH1-OSBPL8_BACH1_chr21_30702014_ENST00000286800_OSBPL8_chr12_76752591_ENST00000393250_length(amino acids)=709AA_BP=596
MLCRMSLSENSVFAYESSVHSTNVLLSLNDQRKKDVLCDVTIFVEGQRFRAHRSVLAACSSYFHSRIVGQADGELNITLPEEVTVKGFEP
LIQFAYTAKLILSKENVDEVCKCVEFLSVHNIEESCFQFLKFKFLDSTADQQECPRKKCFSSHCQKTDLKLSLLDQRDLETDEVEEFLEN
KNVQTPQCKLRRYQGNAKASPPLQDSASQTYESMCLEKDAALALPSLCPKYRKFQKAFGTDRVRTGESSVKDIHASVQPNERSENECLGG
VPECRDLQVMLKCDESKLAMEPEETKKDPASQCPTEKSEVTPFPHNSSIDPHGLYSLSLLHTYDQYGDLNFAGMQNTTVLTEKPLSGTDV
QEKTFGESQDLPLKSDLGTREDSSVASSDRSSVEREVAEHLAKGFWSDICSTDTPCQMQLSPAVAKDGSEQISQKRSECPWLGIRISESP
EPGQRTFTTLSSVNCPFISTLSTEGCSSNLEIGNDDYVSEPQQEPCPYACVISLGDDSETDTEGDSESCSAREQECEVKLPFNAQRIISL
SRNDFQSLLKMHKLTPEQLDCIHDIRRRSKNRIAAQRCRKRKLDCIQNLESEIEKLVSVPKMKHKPTRQQKKVAKGYSSPEPDIQDSSGS

--------------------------------------------------------------
>8826_8826_4_BACH1-OSBPL8_BACH1_chr21_30702014_ENST00000399921_OSBPL8_chr12_76752591_ENST00000261183_length(transcript)=6450nt_BP=2019nt
GTCTACTCAGCCCGGTGGCTGTCGCGCGTGGAATCGCGTAAGAAAAGCCGAGTTTGTGGCTGGGGAGAGAAGGCCACCGTGCTGAGCTGG
ATTTAGCGAAGACTGGTTTTGGGGACCGGAGAGCCCAGGACTCCCTTTGTTGGAGTTTTGCCCACGCGTTGTAATTAAGCCTCGCACAAT
ATGGTTGATGATAATTAGAAGCATGCTTTCCACTGAACTTCCCGACAACATTTGTTATGCAGAATGTCTCTGAGTGAGAACTCGGTTTTT
GCCTATGAATCTTCTGTGCATAGCACCAATGTTTTACTCAGCCTTAATGACCAGCGGAAGAAAGATGTGCTGTGCGATGTCACCATCTTT
GTGGAGGGACAGCGGTTCCGCGCTCACCGGTCCGTGCTGGCGGCATGCAGCAGTTACTTCCACTCAAGAATCGTAGGCCAGGCTGATGGA
GAGCTGAACATTACTCTTCCAGAAGAGGTGACAGTTAAAGGATTTGAACCTTTAATTCAGTTTGCCTACACTGCTAAACTGATTTTAAGT
AAAGAGAATGTGGATGAAGTGTGCAAATGTGTGGAGTTTTTAAGTGTACATAATATTGAGGAATCCTGCTTTCAGTTTCTGAAATTTAAG
TTTTTGGACTCCACTGCAGACCAGCAAGAATGCCCAAGAAAAAAATGCTTTTCATCACACTGTCAGAAAACAGACCTTAAACTTTCACTT
TTGGACCAGAGGGATCTAGAAACTGATGAAGTGGAGGAATTTCTGGAAAATAAAAATGTTCAGACTCCTCAGTGTAAACTCCGCAGGTAT
CAAGGAAATGCAAAAGCCTCACCTCCTCTACAAGACAGTGCCAGTCAGACATATGAGTCCATGTGCTTAGAGAAGGATGCTGCTCTGGCC
TTGCCTTCTTTATGCCCCAAATACAGAAAATTCCAAAAAGCATTTGGAACTGACAGAGTCCGTACTGGGGAATCTAGTGTCAAAGACATT
CATGCTTCTGTTCAGCCAAATGAAAGGTCTGAAAATGAATGCCTGGGAGGAGTCCCGGAGTGTAGAGATTTGCAGGTGATGTTAAAATGT
GACGAAAGTAAATTAGCAATGGAACCTGAAGAAACGAAGAAAGATCCTGCTTCTCAGTGCCCAACTGAAAAATCAGAAGTGACTCCTTTC
CCCCACAATTCTTCCATAGACCCTCATGGACTTTATTCTTTGTCTCTTTTACACACATATGACCAATATGGTGACTTGAATTTTGCTGGT
ATGCAAAACACAACAGTGTTAACAGAAAAGCCTTTGTCAGGTACAGACGTCCAAGAAAAAACATTTGGTGAAAGTCAGGATTTACCTTTG
AAATCCGACTTGGGCACCAGGGAAGATAGTAGTGTTGCATCTAGTGATAGGAGTAGTGTGGAGCGAGAAGTGGCAGAACACCTAGCAAAA
GGCTTCTGGAGTGACATTTGCAGCACGGACACTCCTTGCCAAATGCAGTTATCACCTGCTGTGGCCAAAGATGGCTCAGAACAGATCTCA
CAGAAACGGTCTGAGTGTCCGTGGTTAGGTATCAGGATTAGTGAGAGCCCAGAACCAGGTCAAAGGACTTTCACAACATTAAGTTCTGTC
AACTGCCCTTTTATAAGTACTCTGAGTACTGAAGGCTGTTCAAGCAATTTGGAAATTGGAAACGATGATTATGTTTCAGAACCCCAGCAA
GAACCTTGCCCATATGCTTGTGTCATTAGCTTGGGAGACGACTCTGAGACGGACACCGAAGGAGACAGTGAATCCTGTTCAGCCAGAGAA
CAAGAATGTGAGGTAAAACTGCCATTCAATGCACAACGGATAATTTCACTGTCTCGAAATGATTTTCAGTCCTTGTTGAAAATGCACAAG
CTTACTCCAGAACAGCTGGATTGTATCCATGATATTCGAAGAAGAAGTAAAAACAGAATTGCTGCACAGCGCTGTCGCAAGAGAAAACTT
GACTGTATACAGAATCTTGAATCAGAAATTGAGAAGCTGGTTAGCGTCCCCAAAATGAAACATAAGCCAACCAGGCAACAGAAGAAAGTA
GCAAAAGGCTATTCCTCCCCAGAACCTGACATTCAAGACTCCTCTGGAAGTGAAGCTCAATCAGTAAAACCAAGTACAAGAAGAAAGAAA
GGAATAGAACTGGGAGACATTCAGAGTTCCATCGAATCTATAAAACAAACACAGGAAGAAATTAAAAGAAATATTATGGCTCTTCGAAAT
CATTTAGTTTCAAGCACACCGGCCACGGATTATTTTCTGCAACAAAAAGACTACTTCATCATTTTCCTCCTGATTTTGCTTCAAGTCATA
ATAAACTTCATGTTCAAGTAGAAGTTCTCTACCATTGAATCAGTGAACTAGAAAGATCTGATTTGGCCTGGGACCAGTGTTCAAGTTGGT
TTGGTCTTTATTAAAAATCACAATATTCCGAAAACAAAAAAACCTAGGAGATAAATGTAGAGGTATTGACTTTTCGTATCTTTTATCTTC
ACACTGAAACAAGAGCTATCCTATTTGATTATTAAAGTGAGCTATGTGTTAAGTGCCAGGACATTTCTAGCTTTTGTGAGAATGTGTCTA
CATATGAGTATAATAAACCCACATGTATACACAATTGTCTCTTATGTACTCCTACCTGACAGTAGTCTTTGTATTCTATAGTATGTTCTG
AGATATAATGTTAACATTGTTCATAACAAAAAATGCTATCAATCTTATAAATATATGTAATCTATTTTCTTCATAAAACAGGCACAAAAG
TTTTATCAGTAAGGAATTACAGATTGAGAAATGATGGAATAATAGACATAATTAATTCAATACACTACTGTTAAAATCATTTGCAAAGCA
CTCAGCTCAATTATCTTCTTAGAAAGAAAGAAAAAGTATGAATGGTCAAAATGAATACATCGAGAGAGATAAATGGCAAATTGCTTTTTT
AAAAGTTTACATAAGTTTTTTTTAACCCCTAGAATTTAATATTTGTAGATGCAGGTAAATATATATACTTACGTGTATATCAGTATAAAA
ACACTGGTGTGCAATTAATTGGATTGATTATAATACCACCTTAAGCACTTGCTGAAAAAAGTGTGGTCAAAATTGATTGCTGTCCTTTTG
TCTTATTTTTGTTTTTCTTAAGTCAGCTGGTTCATAACATAGGCCAAATTCTAGAGATGTTTATAGAGCATTTGAAGTGCTGATAATTTA
TGTTTTTTCATTATGAAAACTTATTTTAGCTTTAGACTCCAGTGTGTTCAGTGAATAAGTAGAATATAAAAAAATATAACCAGTATTTTA
CTTCAAAAGCCAAAAAGAGGCAATAAGAAAAGACACTTTGTGGTGGCCTTTATGTGTGCATTAAAATTGGTTTCTGTAAAACGTGTAATA
AGTTGAGTATCTACGAAGAGTATCAAGTTCTGAAGTTTAATTTTTTTATTATCCTCCTCTCTTCTTAGTAACTTCTTTCTGTGGCAAAAC
CACAATTCTTTAAGATTCCTATTGTTCAGGCTAAGGCAAATTTTTTTGTTTGTTTCTTCAGTTTAATATTTTGATTTTGTGTTTTTACGT
AAATATTTATATTCCTTGAAAGCAATTTTTGCCAAGGTAGTTCAGTTTAGGAATATGTTGTTCTAAAATATGTCTTAGAATCCTGAAAGC
ATAGATTTTGAAATGTTTTTTTAATGAAAATGAAGGTCAGAGAGAATAATTGCCCTGACCACATTTGCCTTTCAGTAGGAGGAGGCTGTG
AAATAGTAAAATTATAATCGTTTATGCCATGATAAATACAAGATTGGTAAATAAATACATTGATTGGTAAATTATGAGAATCAAAATGAT
AAAAAGAGCCTGCTTTTTTCCCTAACCAATATAGCTATCTTAAGTATCCTTAGGTTTCTGTGAAGAACCATTTCCCATGTTTTCTTGGCA
AAATAATGCTGTATTCCATATGTACATGTGAAATGATGTTTTAAATTGATAAAAGCTTAAATAAGATCTACCTATACCCAGTATTTTCAT
GATATTAGAACAAATGGGTTTTTGGTTATATTTTATATTTGTCAATATAATTTTTGTATTCACATTCTGTTACACTCTGCCTATTCATTG
ATATATGATATTCTGTAAATATTGTACAATTTGATCTTTTTTATGGTTTAAATTAGTTAATTACATACAAATTGATTGGCTTATCACAAA
AATCATTTCATCAGTAAACCTTGTTAACATTTTGTACTGGTGACCCACCTCTTAGGACTTTGGTCTTATCCACGTGTATGTTGTTTTCAT
TTGGTCCAAATAATATTTTATTTGTATGGGTATCTTCTAAGACTAAATAGGTAGTTGTGTTCTTTATTTTTAAAATTTCTTTTTAGAGCA
AATGTTATGGGTTCTTACCCAAAGAGTCAAAAACTATTTCTTAAGAAAGAGCAGAGTTATTCATGACTGTTCTTTATACACTAAAAGCAT
GCATCTAATCTAATAGTCCTCTTATTATGCTTTTAGTTGTATGAGTCTCTTTCTATGAACTGAACACAAAACTCAGGAATTGGTGGCTTA
ATTTTAGATCAGTGCTTGTACTAGGCTTAGTTATATGAATCTTTATAACACATAATTACTAACTTTGTAGCCATATATGTAATTGACTTT
GAATGTTATTTACCTGAAATTAATCTTCCTTCACACATGGACCGTAAACGGTTCCCAGTTGTCTGAGAGCCTCATGAGGGTTTCTAGGAT
TTATGACCTTATGACCAGTTTTTTTCATTTACCAAGATTTTATTTTCCTACATGAAAATTTAATTGAGTAATAATTATTCACATGTGCAT
TTTCTTTTTAGCTGTTAAATGTACTATGCCATCATCCACCATTTAGTAAAATGTAGCTGGCCCAGGACATGTAAAAAAAAAAAAAAAACA
ACAACAATAAATAGGGCATGTGAAATGTTAAGTTACAGCAATAGATATTTTATTTGTATTTCATGTTAGTACTTTTTTGTTTTATATCAC
TTATAAAGGTACAGTGTACTCTTTGTCACAGCTCAGTTGGTAACCGCATTCCATTGAAAAGTTGGCCTTGTAAAATACAACTCTCATTTA
ATATTCATGCTTTTGTGCCTTTAAGAAAATATTTTTTGTCATTTTTTGTGTTACAGAACTATAATGTGATTCAAGGTGTTTATAGGCTTG
TCATAAAAGGGTCATTTCTGTGTGTTACTTTCTTTTTATATAGCTATAGTATATTTAAACAATAATACTATCTTTTATAGGGGTTTGTCT
ATTTACCTATTCTTTACTCAGACATTGATGTAGACTTGTCAGATTATTCTGAGTATTGTTAACAGTGCCTTTTCGATGGAATCACACTTT
TTGGCTGTCACCTTGTGCCATATACACACAAAATTTTGTGGAAGGCAGTTTTAACTTTCTGAAGAATATCTGTCAAAATTTAAGAAAACA
AATGTATAAAATTCCATTTTTTCCAGTGTTTAGCATTTCTAGTAAGCAGTGAGGTTGTTTGACATACAGTGATGATGGCATTATTGATAA
GCCATACATGAGACTGCAGATTATATTGAATCATATTAAATGTACAGAAATAAAATATTAGATTTATATCAAATTTTCCAATTTGAACCA
GTGGGGAAAATCCCACAGAAATCAGTAAGTTTACATTTCAATTTCTATCTTATTTGACTAAGTGGAAAGAGATTCTTTAAAATGTATAAC
CTGCCATTATGTAATTTGGTTTCATTTTATTCTACCTGTTGTGTGAGTTTAGTATATTTAATTTACTTTTTGTTACTCTTTACATACTGT
TTATTTTTGTTAGTTTTTAATTGAAGATGGACTGTTGAAATTGTATAGGACCAGTGTCTTATTAATATGATTAATATATTTAGAAGAGCC
ACGTGAAACCCATGACAAAATGAATGTGAATATTCTTTCTAAAAATTTAGAAAATGTTATCTTTTTGCATTTATTATGTAAAACTGTTTT
ACAGTATCAAAATTTTTCACTTAAAGAAAAAAAATGCCATGAAACATTTGAACTGATGAGCCACAGAACTTCAGTTGAAATTTTTTTCAC
TTTTTAGCATGCTAAATATACATCTGAGTTTAAATGTTCTGTTTAATGGCCATTCATAAATTCAAGCACTACCACTGGTCAGTTTTGTGT
GATAGAATAAAAATATGTTACCTGCAGTGTAAGTACAGCACACTGTCAAATTCTTTTCCTTAAGGTGCACAGTAAATGTACAGATAGTTA
TAGGCCACTGTTTTGTAATGTAGTACATTTCTAATCTATTATTCCTAACCTATTATAACTGTTTGCAGAAAGAAAAGAATTTTTCTAATA

>8826_8826_4_BACH1-OSBPL8_BACH1_chr21_30702014_ENST00000399921_OSBPL8_chr12_76752591_ENST00000261183_length(amino acids)=709AA_BP=596
MLCRMSLSENSVFAYESSVHSTNVLLSLNDQRKKDVLCDVTIFVEGQRFRAHRSVLAACSSYFHSRIVGQADGELNITLPEEVTVKGFEP
LIQFAYTAKLILSKENVDEVCKCVEFLSVHNIEESCFQFLKFKFLDSTADQQECPRKKCFSSHCQKTDLKLSLLDQRDLETDEVEEFLEN
KNVQTPQCKLRRYQGNAKASPPLQDSASQTYESMCLEKDAALALPSLCPKYRKFQKAFGTDRVRTGESSVKDIHASVQPNERSENECLGG
VPECRDLQVMLKCDESKLAMEPEETKKDPASQCPTEKSEVTPFPHNSSIDPHGLYSLSLLHTYDQYGDLNFAGMQNTTVLTEKPLSGTDV
QEKTFGESQDLPLKSDLGTREDSSVASSDRSSVEREVAEHLAKGFWSDICSTDTPCQMQLSPAVAKDGSEQISQKRSECPWLGIRISESP
EPGQRTFTTLSSVNCPFISTLSTEGCSSNLEIGNDDYVSEPQQEPCPYACVISLGDDSETDTEGDSESCSAREQECEVKLPFNAQRIISL
SRNDFQSLLKMHKLTPEQLDCIHDIRRRSKNRIAAQRCRKRKLDCIQNLESEIEKLVSVPKMKHKPTRQQKKVAKGYSSPEPDIQDSSGS

--------------------------------------------------------------
>8826_8826_5_BACH1-OSBPL8_BACH1_chr21_30702014_ENST00000399921_OSBPL8_chr12_76752591_ENST00000393249_length(transcript)=6453nt_BP=2019nt
GTCTACTCAGCCCGGTGGCTGTCGCGCGTGGAATCGCGTAAGAAAAGCCGAGTTTGTGGCTGGGGAGAGAAGGCCACCGTGCTGAGCTGG
ATTTAGCGAAGACTGGTTTTGGGGACCGGAGAGCCCAGGACTCCCTTTGTTGGAGTTTTGCCCACGCGTTGTAATTAAGCCTCGCACAAT
ATGGTTGATGATAATTAGAAGCATGCTTTCCACTGAACTTCCCGACAACATTTGTTATGCAGAATGTCTCTGAGTGAGAACTCGGTTTTT
GCCTATGAATCTTCTGTGCATAGCACCAATGTTTTACTCAGCCTTAATGACCAGCGGAAGAAAGATGTGCTGTGCGATGTCACCATCTTT
GTGGAGGGACAGCGGTTCCGCGCTCACCGGTCCGTGCTGGCGGCATGCAGCAGTTACTTCCACTCAAGAATCGTAGGCCAGGCTGATGGA
GAGCTGAACATTACTCTTCCAGAAGAGGTGACAGTTAAAGGATTTGAACCTTTAATTCAGTTTGCCTACACTGCTAAACTGATTTTAAGT
AAAGAGAATGTGGATGAAGTGTGCAAATGTGTGGAGTTTTTAAGTGTACATAATATTGAGGAATCCTGCTTTCAGTTTCTGAAATTTAAG
TTTTTGGACTCCACTGCAGACCAGCAAGAATGCCCAAGAAAAAAATGCTTTTCATCACACTGTCAGAAAACAGACCTTAAACTTTCACTT
TTGGACCAGAGGGATCTAGAAACTGATGAAGTGGAGGAATTTCTGGAAAATAAAAATGTTCAGACTCCTCAGTGTAAACTCCGCAGGTAT
CAAGGAAATGCAAAAGCCTCACCTCCTCTACAAGACAGTGCCAGTCAGACATATGAGTCCATGTGCTTAGAGAAGGATGCTGCTCTGGCC
TTGCCTTCTTTATGCCCCAAATACAGAAAATTCCAAAAAGCATTTGGAACTGACAGAGTCCGTACTGGGGAATCTAGTGTCAAAGACATT
CATGCTTCTGTTCAGCCAAATGAAAGGTCTGAAAATGAATGCCTGGGAGGAGTCCCGGAGTGTAGAGATTTGCAGGTGATGTTAAAATGT
GACGAAAGTAAATTAGCAATGGAACCTGAAGAAACGAAGAAAGATCCTGCTTCTCAGTGCCCAACTGAAAAATCAGAAGTGACTCCTTTC
CCCCACAATTCTTCCATAGACCCTCATGGACTTTATTCTTTGTCTCTTTTACACACATATGACCAATATGGTGACTTGAATTTTGCTGGT
ATGCAAAACACAACAGTGTTAACAGAAAAGCCTTTGTCAGGTACAGACGTCCAAGAAAAAACATTTGGTGAAAGTCAGGATTTACCTTTG
AAATCCGACTTGGGCACCAGGGAAGATAGTAGTGTTGCATCTAGTGATAGGAGTAGTGTGGAGCGAGAAGTGGCAGAACACCTAGCAAAA
GGCTTCTGGAGTGACATTTGCAGCACGGACACTCCTTGCCAAATGCAGTTATCACCTGCTGTGGCCAAAGATGGCTCAGAACAGATCTCA
CAGAAACGGTCTGAGTGTCCGTGGTTAGGTATCAGGATTAGTGAGAGCCCAGAACCAGGTCAAAGGACTTTCACAACATTAAGTTCTGTC
AACTGCCCTTTTATAAGTACTCTGAGTACTGAAGGCTGTTCAAGCAATTTGGAAATTGGAAACGATGATTATGTTTCAGAACCCCAGCAA
GAACCTTGCCCATATGCTTGTGTCATTAGCTTGGGAGACGACTCTGAGACGGACACCGAAGGAGACAGTGAATCCTGTTCAGCCAGAGAA
CAAGAATGTGAGGTAAAACTGCCATTCAATGCACAACGGATAATTTCACTGTCTCGAAATGATTTTCAGTCCTTGTTGAAAATGCACAAG
CTTACTCCAGAACAGCTGGATTGTATCCATGATATTCGAAGAAGAAGTAAAAACAGAATTGCTGCACAGCGCTGTCGCAAGAGAAAACTT
GACTGTATACAGAATCTTGAATCAGAAATTGAGAAGCTGGTTAGCGTCCCCAAAATGAAACATAAGCCAACCAGGCAACAGAAGAAAGTA
GCAAAAGGCTATTCCTCCCCAGAACCTGACATTCAAGACTCCTCTGGAAGTGAAGCTCAATCAGTAAAACCAAGTACAAGAAGAAAGAAA
GGAATAGAACTGGGAGACATTCAGAGTTCCATCGAATCTATAAAACAAACACAGGAAGAAATTAAAAGAAATATTATGGCTCTTCGAAAT
CATTTAGTTTCAAGCACACCGGCCACGGATTATTTTCTGCAACAAAAAGACTACTTCATCATTTTCCTCCTGATTTTGCTTCAAGTCATA
ATAAACTTCATGTTCAAGTAGAAGTTCTCTACCATTGAATCAGTGAACTAGAAAGATCTGATTTGGCCTGGGACCAGTGTTCAAGTTGGT
TTGGTCTTTATTAAAAATCACAATATTCCGAAAACAAAAAAACCTAGGAGATAAATGTAGAGGTATTGACTTTTCGTATCTTTTATCTTC
ACACTGAAACAAGAGCTATCCTATTTGATTATTAAAGTGAGCTATGTGTTAAGTGCCAGGACATTTCTAGCTTTTGTGAGAATGTGTCTA
CATATGAGTATAATAAACCCACATGTATACACAATTGTCTCTTATGTACTCCTACCTGACAGTAGTCTTTGTATTCTATAGTATGTTCTG
AGATATAATGTTAACATTGTTCATAACAAAAAATGCTATCAATCTTATAAATATATGTAATCTATTTTCTTCATAAAACAGGCACAAAAG
TTTTATCAGTAAGGAATTACAGATTGAGAAATGATGGAATAATAGACATAATTAATTCAATACACTACTGTTAAAATCATTTGCAAAGCA
CTCAGCTCAATTATCTTCTTAGAAAGAAAGAAAAAGTATGAATGGTCAAAATGAATACATCGAGAGAGATAAATGGCAAATTGCTTTTTT
AAAAGTTTACATAAGTTTTTTTTAACCCCTAGAATTTAATATTTGTAGATGCAGGTAAATATATATACTTACGTGTATATCAGTATAAAA
ACACTGGTGTGCAATTAATTGGATTGATTATAATACCACCTTAAGCACTTGCTGAAAAAAGTGTGGTCAAAATTGATTGCTGTCCTTTTG
TCTTATTTTTGTTTTTCTTAAGTCAGCTGGTTCATAACATAGGCCAAATTCTAGAGATGTTTATAGAGCATTTGAAGTGCTGATAATTTA
TGTTTTTTCATTATGAAAACTTATTTTAGCTTTAGACTCCAGTGTGTTCAGTGAATAAGTAGAATATAAAAAAATATAACCAGTATTTTA
CTTCAAAAGCCAAAAAGAGGCAATAAGAAAAGACACTTTGTGGTGGCCTTTATGTGTGCATTAAAATTGGTTTCTGTAAAACGTGTAATA
AGTTGAGTATCTACGAAGAGTATCAAGTTCTGAAGTTTAATTTTTTTATTATCCTCCTCTCTTCTTAGTAACTTCTTTCTGTGGCAAAAC
CACAATTCTTTAAGATTCCTATTGTTCAGGCTAAGGCAAATTTTTTTGTTTGTTTCTTCAGTTTAATATTTTGATTTTGTGTTTTTACGT
AAATATTTATATTCCTTGAAAGCAATTTTTGCCAAGGTAGTTCAGTTTAGGAATATGTTGTTCTAAAATATGTCTTAGAATCCTGAAAGC
ATAGATTTTGAAATGTTTTTTTAATGAAAATGAAGGTCAGAGAGAATAATTGCCCTGACCACATTTGCCTTTCAGTAGGAGGAGGCTGTG
AAATAGTAAAATTATAATCGTTTATGCCATGATAAATACAAGATTGGTAAATAAATACATTGATTGGTAAATTATGAGAATCAAAATGAT
AAAAAGAGCCTGCTTTTTTCCCTAACCAATATAGCTATCTTAAGTATCCTTAGGTTTCTGTGAAGAACCATTTCCCATGTTTTCTTGGCA
AAATAATGCTGTATTCCATATGTACATGTGAAATGATGTTTTAAATTGATAAAAGCTTAAATAAGATCTACCTATACCCAGTATTTTCAT
GATATTAGAACAAATGGGTTTTTGGTTATATTTTATATTTGTCAATATAATTTTTGTATTCACATTCTGTTACACTCTGCCTATTCATTG
ATATATGATATTCTGTAAATATTGTACAATTTGATCTTTTTTATGGTTTAAATTAGTTAATTACATACAAATTGATTGGCTTATCACAAA
AATCATTTCATCAGTAAACCTTGTTAACATTTTGTACTGGTGACCCACCTCTTAGGACTTTGGTCTTATCCACGTGTATGTTGTTTTCAT
TTGGTCCAAATAATATTTTATTTGTATGGGTATCTTCTAAGACTAAATAGGTAGTTGTGTTCTTTATTTTTAAAATTTCTTTTTAGAGCA
AATGTTATGGGTTCTTACCCAAAGAGTCAAAAACTATTTCTTAAGAAAGAGCAGAGTTATTCATGACTGTTCTTTATACACTAAAAGCAT
GCATCTAATCTAATAGTCCTCTTATTATGCTTTTAGTTGTATGAGTCTCTTTCTATGAACTGAACACAAAACTCAGGAATTGGTGGCTTA
ATTTTAGATCAGTGCTTGTACTAGGCTTAGTTATATGAATCTTTATAACACATAATTACTAACTTTGTAGCCATATATGTAATTGACTTT
GAATGTTATTTACCTGAAATTAATCTTCCTTCACACATGGACCGTAAACGGTTCCCAGTTGTCTGAGAGCCTCATGAGGGTTTCTAGGAT
TTATGACCTTATGACCAGTTTTTTTCATTTACCAAGATTTTATTTTCCTACATGAAAATTTAATTGAGTAATAATTATTCACATGTGCAT
TTTCTTTTTAGCTGTTAAATGTACTATGCCATCATCCACCATTTAGTAAAATGTAGCTGGCCCAGGACATGTAAAAAAAAAAAAAAAACA
ACAACAATAAATAGGGCATGTGAAATGTTAAGTTACAGCAATAGATATTTTATTTGTATTTCATGTTAGTACTTTTTTGTTTTATATCAC
TTATAAAGGTACAGTGTACTCTTTGTCACAGCTCAGTTGGTAACCGCATTCCATTGAAAAGTTGGCCTTGTAAAATACAACTCTCATTTA
ATATTCATGCTTTTGTGCCTTTAAGAAAATATTTTTTGTCATTTTTTGTGTTACAGAACTATAATGTGATTCAAGGTGTTTATAGGCTTG
TCATAAAAGGGTCATTTCTGTGTGTTACTTTCTTTTTATATAGCTATAGTATATTTAAACAATAATACTATCTTTTATAGGGGTTTGTCT
ATTTACCTATTCTTTACTCAGACATTGATGTAGACTTGTCAGATTATTCTGAGTATTGTTAACAGTGCCTTTTCGATGGAATCACACTTT
TTGGCTGTCACCTTGTGCCATATACACACAAAATTTTGTGGAAGGCAGTTTTAACTTTCTGAAGAATATCTGTCAAAATTTAAGAAAACA
AATGTATAAAATTCCATTTTTTCCAGTGTTTAGCATTTCTAGTAAGCAGTGAGGTTGTTTGACATACAGTGATGATGGCATTATTGATAA
GCCATACATGAGACTGCAGATTATATTGAATCATATTAAATGTACAGAAATAAAATATTAGATTTATATCAAATTTTCCAATTTGAACCA
GTGGGGAAAATCCCACAGAAATCAGTAAGTTTACATTTCAATTTCTATCTTATTTGACTAAGTGGAAAGAGATTCTTTAAAATGTATAAC
CTGCCATTATGTAATTTGGTTTCATTTTATTCTACCTGTTGTGTGAGTTTAGTATATTTAATTTACTTTTTGTTACTCTTTACATACTGT
TTATTTTTGTTAGTTTTTAATTGAAGATGGACTGTTGAAATTGTATAGGACCAGTGTCTTATTAATATGATTAATATATTTAGAAGAGCC
ACGTGAAACCCATGACAAAATGAATGTGAATATTCTTTCTAAAAATTTAGAAAATGTTATCTTTTTGCATTTATTATGTAAAACTGTTTT
ACAGTATCAAAATTTTTCACTTAAAGAAAAAAAATGCCATGAAACATTTGAACTGATGAGCCACAGAACTTCAGTTGAAATTTTTTTCAC
TTTTTAGCATGCTAAATATACATCTGAGTTTAAATGTTCTGTTTAATGGCCATTCATAAATTCAAGCACTACCACTGGTCAGTTTTGTGT
GATAGAATAAAAATATGTTACCTGCAGTGTAAGTACAGCACACTGTCAAATTCTTTTCCTTAAGGTGCACAGTAAATGTACAGATAGTTA
TAGGCCACTGTTTTGTAATGTAGTACATTTCTAATCTATTATTCCTAACCTATTATAACTGTTTGCAGAAAGAAAAGAATTTTTCTAATA

>8826_8826_5_BACH1-OSBPL8_BACH1_chr21_30702014_ENST00000399921_OSBPL8_chr12_76752591_ENST00000393249_length(amino acids)=709AA_BP=596
MLCRMSLSENSVFAYESSVHSTNVLLSLNDQRKKDVLCDVTIFVEGQRFRAHRSVLAACSSYFHSRIVGQADGELNITLPEEVTVKGFEP
LIQFAYTAKLILSKENVDEVCKCVEFLSVHNIEESCFQFLKFKFLDSTADQQECPRKKCFSSHCQKTDLKLSLLDQRDLETDEVEEFLEN
KNVQTPQCKLRRYQGNAKASPPLQDSASQTYESMCLEKDAALALPSLCPKYRKFQKAFGTDRVRTGESSVKDIHASVQPNERSENECLGG
VPECRDLQVMLKCDESKLAMEPEETKKDPASQCPTEKSEVTPFPHNSSIDPHGLYSLSLLHTYDQYGDLNFAGMQNTTVLTEKPLSGTDV
QEKTFGESQDLPLKSDLGTREDSSVASSDRSSVEREVAEHLAKGFWSDICSTDTPCQMQLSPAVAKDGSEQISQKRSECPWLGIRISESP
EPGQRTFTTLSSVNCPFISTLSTEGCSSNLEIGNDDYVSEPQQEPCPYACVISLGDDSETDTEGDSESCSAREQECEVKLPFNAQRIISL
SRNDFQSLLKMHKLTPEQLDCIHDIRRRSKNRIAAQRCRKRKLDCIQNLESEIEKLVSVPKMKHKPTRQQKKVAKGYSSPEPDIQDSSGS

--------------------------------------------------------------
>8826_8826_6_BACH1-OSBPL8_BACH1_chr21_30702014_ENST00000399921_OSBPL8_chr12_76752591_ENST00000393250_length(transcript)=2414nt_BP=2019nt
GTCTACTCAGCCCGGTGGCTGTCGCGCGTGGAATCGCGTAAGAAAAGCCGAGTTTGTGGCTGGGGAGAGAAGGCCACCGTGCTGAGCTGG
ATTTAGCGAAGACTGGTTTTGGGGACCGGAGAGCCCAGGACTCCCTTTGTTGGAGTTTTGCCCACGCGTTGTAATTAAGCCTCGCACAAT
ATGGTTGATGATAATTAGAAGCATGCTTTCCACTGAACTTCCCGACAACATTTGTTATGCAGAATGTCTCTGAGTGAGAACTCGGTTTTT
GCCTATGAATCTTCTGTGCATAGCACCAATGTTTTACTCAGCCTTAATGACCAGCGGAAGAAAGATGTGCTGTGCGATGTCACCATCTTT
GTGGAGGGACAGCGGTTCCGCGCTCACCGGTCCGTGCTGGCGGCATGCAGCAGTTACTTCCACTCAAGAATCGTAGGCCAGGCTGATGGA
GAGCTGAACATTACTCTTCCAGAAGAGGTGACAGTTAAAGGATTTGAACCTTTAATTCAGTTTGCCTACACTGCTAAACTGATTTTAAGT
AAAGAGAATGTGGATGAAGTGTGCAAATGTGTGGAGTTTTTAAGTGTACATAATATTGAGGAATCCTGCTTTCAGTTTCTGAAATTTAAG
TTTTTGGACTCCACTGCAGACCAGCAAGAATGCCCAAGAAAAAAATGCTTTTCATCACACTGTCAGAAAACAGACCTTAAACTTTCACTT
TTGGACCAGAGGGATCTAGAAACTGATGAAGTGGAGGAATTTCTGGAAAATAAAAATGTTCAGACTCCTCAGTGTAAACTCCGCAGGTAT
CAAGGAAATGCAAAAGCCTCACCTCCTCTACAAGACAGTGCCAGTCAGACATATGAGTCCATGTGCTTAGAGAAGGATGCTGCTCTGGCC
TTGCCTTCTTTATGCCCCAAATACAGAAAATTCCAAAAAGCATTTGGAACTGACAGAGTCCGTACTGGGGAATCTAGTGTCAAAGACATT
CATGCTTCTGTTCAGCCAAATGAAAGGTCTGAAAATGAATGCCTGGGAGGAGTCCCGGAGTGTAGAGATTTGCAGGTGATGTTAAAATGT
GACGAAAGTAAATTAGCAATGGAACCTGAAGAAACGAAGAAAGATCCTGCTTCTCAGTGCCCAACTGAAAAATCAGAAGTGACTCCTTTC
CCCCACAATTCTTCCATAGACCCTCATGGACTTTATTCTTTGTCTCTTTTACACACATATGACCAATATGGTGACTTGAATTTTGCTGGT
ATGCAAAACACAACAGTGTTAACAGAAAAGCCTTTGTCAGGTACAGACGTCCAAGAAAAAACATTTGGTGAAAGTCAGGATTTACCTTTG
AAATCCGACTTGGGCACCAGGGAAGATAGTAGTGTTGCATCTAGTGATAGGAGTAGTGTGGAGCGAGAAGTGGCAGAACACCTAGCAAAA
GGCTTCTGGAGTGACATTTGCAGCACGGACACTCCTTGCCAAATGCAGTTATCACCTGCTGTGGCCAAAGATGGCTCAGAACAGATCTCA
CAGAAACGGTCTGAGTGTCCGTGGTTAGGTATCAGGATTAGTGAGAGCCCAGAACCAGGTCAAAGGACTTTCACAACATTAAGTTCTGTC
AACTGCCCTTTTATAAGTACTCTGAGTACTGAAGGCTGTTCAAGCAATTTGGAAATTGGAAACGATGATTATGTTTCAGAACCCCAGCAA
GAACCTTGCCCATATGCTTGTGTCATTAGCTTGGGAGACGACTCTGAGACGGACACCGAAGGAGACAGTGAATCCTGTTCAGCCAGAGAA
CAAGAATGTGAGGTAAAACTGCCATTCAATGCACAACGGATAATTTCACTGTCTCGAAATGATTTTCAGTCCTTGTTGAAAATGCACAAG
CTTACTCCAGAACAGCTGGATTGTATCCATGATATTCGAAGAAGAAGTAAAAACAGAATTGCTGCACAGCGCTGTCGCAAGAGAAAACTT
GACTGTATACAGAATCTTGAATCAGAAATTGAGAAGCTGGTTAGCGTCCCCAAAATGAAACATAAGCCAACCAGGCAACAGAAGAAAGTA
GCAAAAGGCTATTCCTCCCCAGAACCTGACATTCAAGACTCCTCTGGAAGTGAAGCTCAATCAGTAAAACCAAGTACAAGAAGAAAGAAA
GGAATAGAACTGGGAGACATTCAGAGTTCCATCGAATCTATAAAACAAACACAGGAAGAAATTAAAAGAAATATTATGGCTCTTCGAAAT
CATTTAGTTTCAAGCACACCGGCCACGGATTATTTTCTGCAACAAAAAGACTACTTCATCATTTTCCTCCTGATTTTGCTTCAAGTCATA

>8826_8826_6_BACH1-OSBPL8_BACH1_chr21_30702014_ENST00000399921_OSBPL8_chr12_76752591_ENST00000393250_length(amino acids)=709AA_BP=596
MLCRMSLSENSVFAYESSVHSTNVLLSLNDQRKKDVLCDVTIFVEGQRFRAHRSVLAACSSYFHSRIVGQADGELNITLPEEVTVKGFEP
LIQFAYTAKLILSKENVDEVCKCVEFLSVHNIEESCFQFLKFKFLDSTADQQECPRKKCFSSHCQKTDLKLSLLDQRDLETDEVEEFLEN
KNVQTPQCKLRRYQGNAKASPPLQDSASQTYESMCLEKDAALALPSLCPKYRKFQKAFGTDRVRTGESSVKDIHASVQPNERSENECLGG
VPECRDLQVMLKCDESKLAMEPEETKKDPASQCPTEKSEVTPFPHNSSIDPHGLYSLSLLHTYDQYGDLNFAGMQNTTVLTEKPLSGTDV
QEKTFGESQDLPLKSDLGTREDSSVASSDRSSVEREVAEHLAKGFWSDICSTDTPCQMQLSPAVAKDGSEQISQKRSECPWLGIRISESP
EPGQRTFTTLSSVNCPFISTLSTEGCSSNLEIGNDDYVSEPQQEPCPYACVISLGDDSETDTEGDSESCSAREQECEVKLPFNAQRIISL
SRNDFQSLLKMHKLTPEQLDCIHDIRRRSKNRIAAQRCRKRKLDCIQNLESEIEKLVSVPKMKHKPTRQQKKVAKGYSSPEPDIQDSSGS

--------------------------------------------------------------

Top

Fusion Gene PPI Analysis for BACH1-OSBPL8


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


Top

Related Drugs for BACH1-OSBPL8


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

Top

Related Diseases for BACH1-OSBPL8


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource