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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:TADA2A-MED24 (FusionGDB2 ID:88692)

Fusion Gene Summary for TADA2A-MED24

check button Fusion gene summary
Fusion gene informationFusion gene name: TADA2A-MED24
Fusion gene ID: 88692
HgeneTgene
Gene symbol

TADA2A

MED24

Gene ID

6871

9862

Gene nametranscriptional adaptor 2Amediator complex subunit 24
SynonymsADA2|ADA2A|KL04P|TADA2L|hADA2ARC100|CRSP100|CRSP4|DRIP100|MED5|THRAP4|TRAP100
Cytomap

17q12

17q21.1

Type of geneprotein-codingprotein-coding
Descriptiontranscriptional adapter 2-alphaADA2-like proteintranscriptional adaptor 2 alphamediator of RNA polymerase II transcription subunit 24CRSP complex subunit 4activator-recruited cofactor 100 kDa componentcofactor required for Sp1 transcriptional activation subunit 4cofactor required for Sp1 transcriptional activation, subunit 4, 10
Modification date2020031320200313
UniProtAcc.

O75448

Ensembl transtripts involved in fusion geneENST00000591992, ENST00000225396, 
ENST00000394395, ENST00000417170, 
ENST00000586023, 		ENST00000394126, 
ENST00000479829, ENST00000356271, 
ENST00000394127, ENST00000394128, 
ENST00000501516, 
Fusion gene scores* DoF score17 X 18 X 7=214216 X 15 X 7=1680
# samples 1823
** MAII scorelog2(18/2142*10)=-3.57288966842058
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(23/1680*10)=-2.86875546672175
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: TADA2A [Title/Abstract] AND MED24 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointTADA2A(35818689)-MED24(38192407), # samples:3
Anticipated loss of major functional domain due to fusion event.TADA2A-MED24 seems lost the major protein functional domain in Hgene partner, which is a epigenetic factor due to the frame-shifted ORF.
TADA2A-MED24 seems lost the major protein functional domain in Hgene partner, which is a essential gene due to the frame-shifted ORF.
TADA2A-MED24 seems lost the major protein functional domain in Tgene partner, which is a cell metabolism gene due to the frame-shifted ORF.
TADA2A-MED24 seems lost the major protein functional domain in Tgene partner, which is a essential gene due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneTADA2A

GO:0043966

histone H3 acetylation

9674425

TgeneMED24

GO:0006367

transcription initiation from RNA polymerase II promoter

12218053

TgeneMED24

GO:0045893

positive regulation of transcription, DNA-templated

10198638


check buttonFusion gene breakpoints across TADA2A (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across MED24 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4BRCATCGA-AR-A0TQ-01ATADA2Achr17

35802753

+MED24chr17

38192407

-
ChimerDB4BRCATCGA-AR-A0TQ-01ATADA2Achr17

35804870

+MED24chr17

38192407

-
ChimerDB4BRCATCGA-AR-A0TQ-01ATADA2Achr17

35818689

-MED24chr17

38192407

-
ChimerDB4BRCATCGA-AR-A0TQ-01ATADA2Achr17

35818689

+MED24chr17

38192407

-
ChimerDB4BRCATCGA-AR-A0TQTADA2Achr17

35802753

+MED24chr17

38192407

-
ChimerDB4BRCATCGA-AR-A0TQTADA2Achr17

35804870

+MED24chr17

38192407

-


Top

Fusion Gene ORF analysis for TADA2A-MED24

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
3UTR-3CDSENST00000591992ENST00000394126TADA2Achr17

35818689

+MED24chr17

38192407

-
3UTR-3CDSENST00000591992ENST00000394126TADA2Achr17

35802753

+MED24chr17

38192407

-
3UTR-3CDSENST00000591992ENST00000394126TADA2Achr17

35804870

+MED24chr17

38192407

-
3UTR-5UTRENST00000591992ENST00000479829TADA2Achr17

35818689

+MED24chr17

38192407

-
3UTR-5UTRENST00000591992ENST00000479829TADA2Achr17

35802753

+MED24chr17

38192407

-
3UTR-5UTRENST00000591992ENST00000479829TADA2Achr17

35804870

+MED24chr17

38192407

-
3UTR-intronENST00000591992ENST00000356271TADA2Achr17

35818689

+MED24chr17

38192407

-
3UTR-intronENST00000591992ENST00000356271TADA2Achr17

35802753

+MED24chr17

38192407

-
3UTR-intronENST00000591992ENST00000356271TADA2Achr17

35804870

+MED24chr17

38192407

-
3UTR-intronENST00000591992ENST00000394127TADA2Achr17

35818689

+MED24chr17

38192407

-
3UTR-intronENST00000591992ENST00000394127TADA2Achr17

35802753

+MED24chr17

38192407

-
3UTR-intronENST00000591992ENST00000394127TADA2Achr17

35804870

+MED24chr17

38192407

-
3UTR-intronENST00000591992ENST00000394128TADA2Achr17

35818689

+MED24chr17

38192407

-
3UTR-intronENST00000591992ENST00000394128TADA2Achr17

35802753

+MED24chr17

38192407

-
3UTR-intronENST00000591992ENST00000394128TADA2Achr17

35804870

+MED24chr17

38192407

-
3UTR-intronENST00000591992ENST00000501516TADA2Achr17

35818689

+MED24chr17

38192407

-
3UTR-intronENST00000591992ENST00000501516TADA2Achr17

35802753

+MED24chr17

38192407

-
3UTR-intronENST00000591992ENST00000501516TADA2Achr17

35804870

+MED24chr17

38192407

-
5CDS-5UTRENST00000225396ENST00000479829TADA2Achr17

35818689

+MED24chr17

38192407

-
5CDS-5UTRENST00000225396ENST00000479829TADA2Achr17

35802753

+MED24chr17

38192407

-
5CDS-5UTRENST00000225396ENST00000479829TADA2Achr17

35804870

+MED24chr17

38192407

-
5CDS-5UTRENST00000394395ENST00000479829TADA2Achr17

35818689

+MED24chr17

38192407

-
5CDS-5UTRENST00000394395ENST00000479829TADA2Achr17

35802753

+MED24chr17

38192407

-
5CDS-5UTRENST00000394395ENST00000479829TADA2Achr17

35804870

+MED24chr17

38192407

-
5CDS-5UTRENST00000417170ENST00000479829TADA2Achr17

35818689

+MED24chr17

38192407

-
5CDS-5UTRENST00000417170ENST00000479829TADA2Achr17

35802753

+MED24chr17

38192407

-
5CDS-5UTRENST00000417170ENST00000479829TADA2Achr17

35804870

+MED24chr17

38192407

-
5CDS-5UTRENST00000586023ENST00000479829TADA2Achr17

35818689

+MED24chr17

38192407

-
5CDS-5UTRENST00000586023ENST00000479829TADA2Achr17

35802753

+MED24chr17

38192407

-
5CDS-5UTRENST00000586023ENST00000479829TADA2Achr17

35804870

+MED24chr17

38192407

-
5CDS-intronENST00000225396ENST00000356271TADA2Achr17

35818689

+MED24chr17

38192407

-
5CDS-intronENST00000225396ENST00000356271TADA2Achr17

35802753

+MED24chr17

38192407

-
5CDS-intronENST00000225396ENST00000356271TADA2Achr17

35804870

+MED24chr17

38192407

-
5CDS-intronENST00000225396ENST00000394127TADA2Achr17

35818689

+MED24chr17

38192407

-
5CDS-intronENST00000225396ENST00000394127TADA2Achr17

35802753

+MED24chr17

38192407

-
5CDS-intronENST00000225396ENST00000394127TADA2Achr17

35804870

+MED24chr17

38192407

-
5CDS-intronENST00000225396ENST00000394128TADA2Achr17

35818689

+MED24chr17

38192407

-
5CDS-intronENST00000225396ENST00000394128TADA2Achr17

35802753

+MED24chr17

38192407

-
5CDS-intronENST00000225396ENST00000394128TADA2Achr17

35804870

+MED24chr17

38192407

-
5CDS-intronENST00000225396ENST00000501516TADA2Achr17

35818689

+MED24chr17

38192407

-
5CDS-intronENST00000225396ENST00000501516TADA2Achr17

35802753

+MED24chr17

38192407

-
5CDS-intronENST00000225396ENST00000501516TADA2Achr17

35804870

+MED24chr17

38192407

-
5CDS-intronENST00000394395ENST00000356271TADA2Achr17

35818689

+MED24chr17

38192407

-
5CDS-intronENST00000394395ENST00000356271TADA2Achr17

35802753

+MED24chr17

38192407

-
5CDS-intronENST00000394395ENST00000356271TADA2Achr17

35804870

+MED24chr17

38192407

-
5CDS-intronENST00000394395ENST00000394127TADA2Achr17

35818689

+MED24chr17

38192407

-
5CDS-intronENST00000394395ENST00000394127TADA2Achr17

35802753

+MED24chr17

38192407

-
5CDS-intronENST00000394395ENST00000394127TADA2Achr17

35804870

+MED24chr17

38192407

-
5CDS-intronENST00000394395ENST00000394128TADA2Achr17

35818689

+MED24chr17

38192407

-
5CDS-intronENST00000394395ENST00000394128TADA2Achr17

35802753

+MED24chr17

38192407

-
5CDS-intronENST00000394395ENST00000394128TADA2Achr17

35804870

+MED24chr17

38192407

-
5CDS-intronENST00000394395ENST00000501516TADA2Achr17

35818689

+MED24chr17

38192407

-
5CDS-intronENST00000394395ENST00000501516TADA2Achr17

35802753

+MED24chr17

38192407

-
5CDS-intronENST00000394395ENST00000501516TADA2Achr17

35804870

+MED24chr17

38192407

-
5CDS-intronENST00000417170ENST00000356271TADA2Achr17

35818689

+MED24chr17

38192407

-
5CDS-intronENST00000417170ENST00000356271TADA2Achr17

35802753

+MED24chr17

38192407

-
5CDS-intronENST00000417170ENST00000356271TADA2Achr17

35804870

+MED24chr17

38192407

-
5CDS-intronENST00000417170ENST00000394127TADA2Achr17

35818689

+MED24chr17

38192407

-
5CDS-intronENST00000417170ENST00000394127TADA2Achr17

35802753

+MED24chr17

38192407

-
5CDS-intronENST00000417170ENST00000394127TADA2Achr17

35804870

+MED24chr17

38192407

-
5CDS-intronENST00000417170ENST00000394128TADA2Achr17

35818689

+MED24chr17

38192407

-
5CDS-intronENST00000417170ENST00000394128TADA2Achr17

35802753

+MED24chr17

38192407

-
5CDS-intronENST00000417170ENST00000394128TADA2Achr17

35804870

+MED24chr17

38192407

-
5CDS-intronENST00000417170ENST00000501516TADA2Achr17

35818689

+MED24chr17

38192407

-
5CDS-intronENST00000417170ENST00000501516TADA2Achr17

35802753

+MED24chr17

38192407

-
5CDS-intronENST00000417170ENST00000501516TADA2Achr17

35804870

+MED24chr17

38192407

-
5CDS-intronENST00000586023ENST00000356271TADA2Achr17

35818689

+MED24chr17

38192407

-
5CDS-intronENST00000586023ENST00000356271TADA2Achr17

35802753

+MED24chr17

38192407

-
5CDS-intronENST00000586023ENST00000356271TADA2Achr17

35804870

+MED24chr17

38192407

-
5CDS-intronENST00000586023ENST00000394127TADA2Achr17

35818689

+MED24chr17

38192407

-
5CDS-intronENST00000586023ENST00000394127TADA2Achr17

35802753

+MED24chr17

38192407

-
5CDS-intronENST00000586023ENST00000394127TADA2Achr17

35804870

+MED24chr17

38192407

-
5CDS-intronENST00000586023ENST00000394128TADA2Achr17

35818689

+MED24chr17

38192407

-
5CDS-intronENST00000586023ENST00000394128TADA2Achr17

35802753

+MED24chr17

38192407

-
5CDS-intronENST00000586023ENST00000394128TADA2Achr17

35804870

+MED24chr17

38192407

-
5CDS-intronENST00000586023ENST00000501516TADA2Achr17

35818689

+MED24chr17

38192407

-
5CDS-intronENST00000586023ENST00000501516TADA2Achr17

35802753

+MED24chr17

38192407

-
5CDS-intronENST00000586023ENST00000501516TADA2Achr17

35804870

+MED24chr17

38192407

-
Frame-shiftENST00000225396ENST00000394126TADA2Achr17

35818689

+MED24chr17

38192407

-
Frame-shiftENST00000225396ENST00000394126TADA2Achr17

35804870

+MED24chr17

38192407

-
Frame-shiftENST00000394395ENST00000394126TADA2Achr17

35818689

+MED24chr17

38192407

-
Frame-shiftENST00000394395ENST00000394126TADA2Achr17

35804870

+MED24chr17

38192407

-
Frame-shiftENST00000417170ENST00000394126TADA2Achr17

35818689

+MED24chr17

38192407

-
Frame-shiftENST00000417170ENST00000394126TADA2Achr17

35804870

+MED24chr17

38192407

-
Frame-shiftENST00000586023ENST00000394126TADA2Achr17

35818689

+MED24chr17

38192407

-
Frame-shiftENST00000586023ENST00000394126TADA2Achr17

35804870

+MED24chr17

38192407

-
In-frameENST00000225396ENST00000394126TADA2Achr17

35802753

+MED24chr17

38192407

-
In-frameENST00000394395ENST00000394126TADA2Achr17

35802753

+MED24chr17

38192407

-
In-frameENST00000417170ENST00000394126TADA2Achr17

35802753

+MED24chr17

38192407

-
In-frameENST00000586023ENST00000394126TADA2Achr17

35802753

+MED24chr17

38192407

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000394395TADA2Achr1735802753+ENST00000394126MED24chr1738192407-389370417334601095
ENST00000586023TADA2Achr1735802753+ENST00000394126MED24chr1738192407-382863910833951095
ENST00000225396TADA2Achr1735802753+ENST00000394126MED24chr1738192407-409090137036571095
ENST00000417170TADA2Achr1735802753+ENST00000394126MED24chr1738192407-408990036936561095

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000394395ENST00000394126TADA2Achr1735802753+MED24chr1738192407-0.006230420.9937696
ENST00000586023ENST00000394126TADA2Achr1735802753+MED24chr1738192407-0.0062934560.9937065
ENST00000225396ENST00000394126TADA2Achr1735802753+MED24chr1738192407-0.0078649740.99213505
ENST00000417170ENST00000394126TADA2Achr1735802753+MED24chr1738192407-0.007857620.9921423

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Fusion Genomic Features for TADA2A-MED24


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for TADA2A-MED24


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr17:35818689/chr17:38192407)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
.MED24

O75448

FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. {ECO:0000269|PubMed:12218053, ECO:0000269|PubMed:16595664}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneTADA2Achr17:35802753chr17:38192407ENST00000225396+71617_45177444.0Compositional biasNote=Cys-rich
HgeneTADA2Achr17:35802753chr17:38192407ENST00000394395+71617_45177444.0Compositional biasNote=Cys-rich
HgeneTADA2Achr17:35802753chr17:38192407ENST00000417170+71117_45177306.0Compositional biasNote=Cys-rich
HgeneTADA2Achr17:35802753chr17:38192407ENST00000586023+71117_45177306.0Compositional biasNote=Cys-rich
HgeneTADA2Achr17:35802753chr17:38192407ENST00000225396+71670_122177444.0DomainSANT
HgeneTADA2Achr17:35802753chr17:38192407ENST00000394395+71670_122177444.0DomainSANT
HgeneTADA2Achr17:35802753chr17:38192407ENST00000417170+71170_122177306.0DomainSANT
HgeneTADA2Achr17:35802753chr17:38192407ENST00000586023+71170_122177306.0DomainSANT
TgeneMED24chr17:35802753chr17:38192407ENST00000356271025128_1320977.0MotifNote=LXXLL motif 1
TgeneMED24chr17:35802753chr17:38192407ENST00000356271025344_3480977.0MotifNote=LXXLL motif 2
TgeneMED24chr17:35802753chr17:38192407ENST00000356271025448_4520977.0MotifNote=LXXLL motif 3
TgeneMED24chr17:35802753chr17:38192407ENST00000356271025557_5610977.0MotifNote=LXXLL motif 4
TgeneMED24chr17:35802753chr17:38192407ENST00000356271025788_7920977.0MotifNote=LXXLL motif 5
TgeneMED24chr17:35802753chr17:38192407ENST00000356271025857_8610977.0MotifNote=LXXLL motif 6
TgeneMED24chr17:35802753chr17:38192407ENST00000394127025128_1320977.0MotifNote=LXXLL motif 1
TgeneMED24chr17:35802753chr17:38192407ENST00000394127025344_3480977.0MotifNote=LXXLL motif 2
TgeneMED24chr17:35802753chr17:38192407ENST00000394127025448_4520977.0MotifNote=LXXLL motif 3
TgeneMED24chr17:35802753chr17:38192407ENST00000394127025557_5610977.0MotifNote=LXXLL motif 4
TgeneMED24chr17:35802753chr17:38192407ENST00000394127025788_7920977.0MotifNote=LXXLL motif 5
TgeneMED24chr17:35802753chr17:38192407ENST00000394127025857_8610977.0MotifNote=LXXLL motif 6
TgeneMED24chr17:35802753chr17:38192407ENST00000394128226128_13271990.0MotifNote=LXXLL motif 1
TgeneMED24chr17:35802753chr17:38192407ENST00000394128226344_34871990.0MotifNote=LXXLL motif 2
TgeneMED24chr17:35802753chr17:38192407ENST00000394128226448_45271990.0MotifNote=LXXLL motif 3
TgeneMED24chr17:35802753chr17:38192407ENST00000394128226557_56171990.0MotifNote=LXXLL motif 4
TgeneMED24chr17:35802753chr17:38192407ENST00000394128226788_79271990.0MotifNote=LXXLL motif 5
TgeneMED24chr17:35802753chr17:38192407ENST00000394128226857_86171990.0MotifNote=LXXLL motif 6

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneTADA2Achr17:35802753chr17:38192407ENST00000225396+716426_435177444.0DNA bindingOntology_term=ECO:0000250
HgeneTADA2Achr17:35802753chr17:38192407ENST00000394395+716426_435177444.0DNA bindingOntology_term=ECO:0000250
HgeneTADA2Achr17:35802753chr17:38192407ENST00000417170+711426_435177306.0DNA bindingOntology_term=ECO:0000250
HgeneTADA2Achr17:35802753chr17:38192407ENST00000586023+711426_435177306.0DNA bindingOntology_term=ECO:0000250
HgeneTADA2Achr17:35802753chr17:38192407ENST00000225396+716356_443177444.0DomainSWIRM
HgeneTADA2Achr17:35802753chr17:38192407ENST00000394395+716356_443177444.0DomainSWIRM
HgeneTADA2Achr17:35802753chr17:38192407ENST00000417170+711356_443177306.0DomainSWIRM
HgeneTADA2Achr17:35802753chr17:38192407ENST00000586023+711356_443177306.0DomainSWIRM


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Fusion Gene Sequence for TADA2A-MED24


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>88692_88692_1_TADA2A-MED24_TADA2A_chr17_35802753_ENST00000225396_MED24_chr17_38192407_ENST00000394126_length(transcript)=4090nt_BP=901nt
ATTTCCCGCTCAGCCCTGGAGCGCGTAGCTCTACCAAGAATGGCCACTGTGCCAGATGCCCCTGACCAGCGTTGCCCATTTGAATTTCCT
AGCAGGCCCCCCAAAGTAGGTATTTCAGTACCCTGTTAGAGCTGAGGCGCAGGTAAAATGACTGGCCCAGGCCGGTCCCACCCCGTAAGG
ATTTGAACGTTGGCTCCACAACTCGGGAGCCTGCGCCTTTCCTCCTCCCAACGTGGACTCCTGCCCGGCGAAGTGCCTCACTTCCTTCTC
CCGGGAGTCATCAAGCTTTGGTGTATGTGTTGGCCGGTTCTGAAGTCTTGAAGAAGCTCTGCTGAGGAAGACCAAAGCAGCACTCGTTGC
CAATTAGGGAATGGACCGTTTGGGTCCCTTTAGCAATGATCCCTCTGATAAGCCACCTTGCCGAGGCTGCTCCTCCTACCTCATGGAGCC
TTATATCAAGTGTGCTGAATGTGGGCCACCTCCTTTTTTCCTCTGCTTGCAGTGTTTCACTCGAGGCTTTGAGTACAAGAAACATCAAAG
CGATCATACTTATGAAATAATGACTTCAGATTTTCCTGTCCTTGATCCCAGCTGGACTGCTCAAGAAGAAATGGCCCTTTTAGAAGCTGT
GATGGACTGTGGCTTTGGAAATTGGCAGGATGTAGCCAATCAAATGTGCACCAAGACCAAGGAGGAGTGTGAGAAGCACTATATGAAGCA
TTTCATCAATAACCCTCTGTTTGCATCTACCCTGCTGAACCTGAAACAAGCAGAGGAAGCAAAAACTGCTGACACAGCCATTCCATTTCA
CTCTACAGATGACCCTCCCCGACCTACCTTTGACTCCTTGCTTTCTCGGGACATGGCCGGGTACATGCCAGCTCGAGCAGATTTCATTGA
GATGGTGTCCTACTCTTCTGTCCTCACAGCCATCAGTAAGTTTGATGACTTTTCTCGGGACCTGTGTGTCCAGGCATTGCTGGACATCAT
GGACATGTTTTGTGACCGTCTGAGCTGTCACGGCAAAGCAGAGGAATGCATCGGACTGTGCCGAGCCCTTCTTAGCGCCCTCCACTGGCT
GCTGCGCTGCACGGCAGCCTCTGCAGAGCGGCTGCGGGAGGGGCTGGAGGCCGGCACTCCAGCCGCTGGGGAGAAGCAGCTTGCCATGTG
CCTTCAGCGCCTGGAGAAAACCCTCAGCAGCACCAAGAACCGGGCCCTGCTGCACATCGCCAAACTAGAGGAGGCCTCTTCTTGGACTGC
CATCGAGCATTCTCTCTTGAAACTTGGAGAGATCCTGGCCAATCTCAGCAACCCGCAGCTCCGGAGTCAGGCCGAGCAGTGTGGCACCCT
CATTAGGAGCATCCCCACGATGCTGTCTGTGCATGCGGAGCAGATGCACAAGACCGGCTTCCCCACTGTCCACGCCGTGATCCTGCTCGA
GGGCACCATGAACCTGACAGGCGAGACGCAGTCCCTGGTGGAGCAGCTGACGATGGTGAAGCGCATGCAGCATATCCCCACCCCACTTTT
TGTCCTGGAGATCTGGAAAGCTTGCTTCGTGGGGCTCATTGAGTCTCCCGAGGGTACGGAGGAGCTCAAGTGGACAGCTTTCACTTTCCT
CAAGATTCCACAGGTTTTGGTGAAGTTGAAGAAGTACTCTCATGGAGACAAGGACTTCACTGAGGATGTCAACTGTGCTTTTGAGTTCCT
GCTGAAGCTCACCCCCTTGTTGGACAAAGCTGACCAGCGCTGCAACTGTGACTGTACAAACTTCCTGCTCCAAGAATGTGGCAAGCAGGG
GCTTCTGTCTGAGGCCAGCGTCAACAACCTTATGGCTAAGCGCAAAGCGGACCGAGAGCACGCACCCCAGCAGAAATCGGGAGAGAATGC
CAACATCCAGCCCAACATCCAGCTGATCCTCCGGGCGGAGCCCACTGTCACAAACATCCTCAAGACGATGGATGCAGACCACTCTAAGTC
ACCGGAGGGACTGCTGGGAGTCCTGGGCCACATGCTGTCCGGGAAGAGTCTGGACTTGCTGCTGGCTGCCGCCGCCGCCACTGGAAAGCT
GAAATCCTTCGCCCGGAAATTCATCAATTTGAATGAATTCACAACCTATGGCAGCGAAGAAAGCACCAAACCGGCCTCCGTCCGGGCCCT
GCTGTTTGACATCTCCTTCCTCATGCTGTGCCATGTGGCCCAGACCTATGGTTCAGAGGTGATTCTGTCCGAGTCGCGCACAGGAGCTGA
GGTGCCCTTCTTCGAGACCTGGATGCAGACCTGCATGCCTGAGGAGGGCAAGATCCTGAACCCTGACCACCCCTGCTTCCGCCCCGACTC
CACCAAAGTGGAGTCCCTGGTGGCCCTGCTCAACAACTCCTCGGAGATGAAGCTAGTGCAGATGAAGTGGCATGAGGCCTGTCTCAGCAT
CTCAGCCGCCATCTTGGAAATCCTCAATGCCTGGGAGAATGGGGTCCTGGCCTTCGAGTCCATCCAGAAAATCACTGATAACATCAAAGG
GAAGGTATGCAGTCTGGCGGTGTGTGCTGTGGCTTGGCTTGTGGCCCACGTCCGGATGCTGGGGCTGGATGAGCGTGAGAAGTCGCTGCA
GATGATCCGCCAGCTGGCAGGGCCACTGTTTAGTGAGAACACCCTGCAGTTCTACAATGAGAGGGTGGTGATCATGAACTCGATCCTGGA
GCGCATGTGTGCCGACGTGCTGCAGCAGACAGCCACGCAGATCAAGTTTCCCTCCACCGGGGTGGACACAATGCCCTACTGGAACCTGCT
GCCCCCCAAGCGGCCCATCAAAGAGGTGCTGACGGACATTTTTGCCAAGGTGCTGGAGAAGGGCTGGGTGGACAGCCGCTCCATCCACAT
CTTTGACACCCTGCTGCACATGGGCGGCGTCTACTGGTTCTGCAACAACCTGATTAAGGAGCTGCTGAAGGAGACGCGGAAGGAGCACAC
GCTGCGGGCAGTGGAGCTGCTCTACTCCATCTTCTGCCTGGACATGCAGCAAGTGACCCTGGTCCTGCTGGGCCACATCCTACCTGGCCT
GCTCACTGACTCCTCCAAGTGGCACAGCCTCATGGACCCCCCGGGCACTGCTCTTGCCAAGCTGGCCGTGTGGTGTGCCCTCAGTTCCTA
CTCCTCCCACAAGGGACAGGCGTCCACCCGCCAGAAGAAGAGACACCGCGAAGACATTGAGGATTATATCAGCCTCTTCCCCCTGGACGA
TGTGCAGCCTTCGAAGTTGATGCGACTGCTGAGCTCTAATGAGGACGATGCCAACATCCTTTCGAGCCCCACAGACCGATCCATGAGCAG
CTCCCTCTCAGCCTCTCAGCTCCACACGGTCAACATGCGGGACCCTCTGAACCGAGTCCTGGCCAACCTGTTCCTGCTCATCTCCTCCAT
CCTGGGGTCTCGCACCGCTGGCCCCCACACCCAGTTCGTGCAGTGGTTCATGGAGGAGTGTGTGGACTGCCTGGAGCAGGGTGGCCGTGG
CAGCGTCCTGCAGTTCATGCCCTTCACCACCGTGTCGGAACTGGTGAAGGTGTCAGCCATGTCCAGCCCCAAGGTGGTTCTGGCCATCAC
GGACCTCAGCCTGCCCCTGGGCCGCCAGGTGGCTGCTAAAGCCATTGCTGCACTCTGAGGGGCTTGGCATGGCCGCAGTGGGGGCTGGGG
ACTGGCGCAGCCCCAGGCGCCTCCAAGGGAAGCAGTGAGGAAAGATGAGGCATCGTGCCTCACATCCGCTCCACATGGTGCAAGAGCCTC
TAGCGGCTTCCAGTTCCCCGCTCCTGACTCCTGACCTCCAGGATGTCTCCCGGTTTCTTCTTTCAAAATTTCCTCTCCATCTGCTGGCAC
CTGAGGAGAGTGAGCAGCCTGGACCACAAGCCCAGTGGTCACCCCTGTGTGCGCCCGCCCCAGCCCAGGAGTAGTCTTACCTCTGAGGAA
CTTTCTAGATGCAAAGTGTGTATGTGTGTGTGTGTGTGTGTGTGTGTGTGTTTGTGTGTATTTTGTAATATGTGAGGGAAATCTACCTTC

>88692_88692_1_TADA2A-MED24_TADA2A_chr17_35802753_ENST00000225396_MED24_chr17_38192407_ENST00000394126_length(amino acids)=1095AA_BP=177
MDRLGPFSNDPSDKPPCRGCSSYLMEPYIKCAECGPPPFFLCLQCFTRGFEYKKHQSDHTYEIMTSDFPVLDPSWTAQEEMALLEAVMDC
GFGNWQDVANQMCTKTKEECEKHYMKHFINNPLFASTLLNLKQAEEAKTADTAIPFHSTDDPPRPTFDSLLSRDMAGYMPARADFIEMVS
YSSVLTAISKFDDFSRDLCVQALLDIMDMFCDRLSCHGKAEECIGLCRALLSALHWLLRCTAASAERLREGLEAGTPAAGEKQLAMCLQR
LEKTLSSTKNRALLHIAKLEEASSWTAIEHSLLKLGEILANLSNPQLRSQAEQCGTLIRSIPTMLSVHAEQMHKTGFPTVHAVILLEGTM
NLTGETQSLVEQLTMVKRMQHIPTPLFVLEIWKACFVGLIESPEGTEELKWTAFTFLKIPQVLVKLKKYSHGDKDFTEDVNCAFEFLLKL
TPLLDKADQRCNCDCTNFLLQECGKQGLLSEASVNNLMAKRKADREHAPQQKSGENANIQPNIQLILRAEPTVTNILKTMDADHSKSPEG
LLGVLGHMLSGKSLDLLLAAAAATGKLKSFARKFINLNEFTTYGSEESTKPASVRALLFDISFLMLCHVAQTYGSEVILSESRTGAEVPF
FETWMQTCMPEEGKILNPDHPCFRPDSTKVESLVALLNNSSEMKLVQMKWHEACLSISAAILEILNAWENGVLAFESIQKITDNIKGKVC
SLAVCAVAWLVAHVRMLGLDEREKSLQMIRQLAGPLFSENTLQFYNERVVIMNSILERMCADVLQQTATQIKFPSTGVDTMPYWNLLPPK
RPIKEVLTDIFAKVLEKGWVDSRSIHIFDTLLHMGGVYWFCNNLIKELLKETRKEHTLRAVELLYSIFCLDMQQVTLVLLGHILPGLLTD
SSKWHSLMDPPGTALAKLAVWCALSSYSSHKGQASTRQKKRHREDIEDYISLFPLDDVQPSKLMRLLSSNEDDANILSSPTDRSMSSSLS
ASQLHTVNMRDPLNRVLANLFLLISSILGSRTAGPHTQFVQWFMEECVDCLEQGGRGSVLQFMPFTTVSELVKVSAMSSPKVVLAITDLS

--------------------------------------------------------------
>88692_88692_2_TADA2A-MED24_TADA2A_chr17_35802753_ENST00000394395_MED24_chr17_38192407_ENST00000394126_length(transcript)=3893nt_BP=704nt
CCGGGGGCGCGCACGCAAAGCCCGGAGGCGCGCGCGACCGGCGGCTCTTTGGCGCGGATTAGGGGGTCTCGGCGAGGGAGTCATCAAGCT
TTGGTGTATGTGTTGGCCGGTTCTGAAGTCTTGAAGAAGCTCTGCTGAGGAAGACCAAAGCAGCACTCGTTGCCAATTAGGGAATGGACC
GTTTGGGTCCCTTTAGCAATGATCCCTCTGATAAGCCACCTTGCCGAGGCTGCTCCTCCTACCTCATGGAGCCTTATATCAAGTGTGCTG
AATGTGGGCCACCTCCTTTTTTCCTCTGCTTGCAGTGTTTCACTCGAGGCTTTGAGTACAAGAAACATCAAAGCGATCATACTTATGAAA
TAATGACTTCAGATTTTCCTGTCCTTGATCCCAGCTGGACTGCTCAAGAAGAAATGGCCCTTTTAGAAGCTGTGATGGACTGTGGCTTTG
GAAATTGGCAGGATGTAGCCAATCAAATGTGCACCAAGACCAAGGAGGAGTGTGAGAAGCACTATATGAAGCATTTCATCAATAACCCTC
TGTTTGCATCTACCCTGCTGAACCTGAAACAAGCAGAGGAAGCAAAAACTGCTGACACAGCCATTCCATTTCACTCTACAGATGACCCTC
CCCGACCTACCTTTGACTCCTTGCTTTCTCGGGACATGGCCGGGTACATGCCAGCTCGAGCAGATTTCATTGAGATGGTGTCCTACTCTT
CTGTCCTCACAGCCATCAGTAAGTTTGATGACTTTTCTCGGGACCTGTGTGTCCAGGCATTGCTGGACATCATGGACATGTTTTGTGACC
GTCTGAGCTGTCACGGCAAAGCAGAGGAATGCATCGGACTGTGCCGAGCCCTTCTTAGCGCCCTCCACTGGCTGCTGCGCTGCACGGCAG
CCTCTGCAGAGCGGCTGCGGGAGGGGCTGGAGGCCGGCACTCCAGCCGCTGGGGAGAAGCAGCTTGCCATGTGCCTTCAGCGCCTGGAGA
AAACCCTCAGCAGCACCAAGAACCGGGCCCTGCTGCACATCGCCAAACTAGAGGAGGCCTCTTCTTGGACTGCCATCGAGCATTCTCTCT
TGAAACTTGGAGAGATCCTGGCCAATCTCAGCAACCCGCAGCTCCGGAGTCAGGCCGAGCAGTGTGGCACCCTCATTAGGAGCATCCCCA
CGATGCTGTCTGTGCATGCGGAGCAGATGCACAAGACCGGCTTCCCCACTGTCCACGCCGTGATCCTGCTCGAGGGCACCATGAACCTGA
CAGGCGAGACGCAGTCCCTGGTGGAGCAGCTGACGATGGTGAAGCGCATGCAGCATATCCCCACCCCACTTTTTGTCCTGGAGATCTGGA
AAGCTTGCTTCGTGGGGCTCATTGAGTCTCCCGAGGGTACGGAGGAGCTCAAGTGGACAGCTTTCACTTTCCTCAAGATTCCACAGGTTT
TGGTGAAGTTGAAGAAGTACTCTCATGGAGACAAGGACTTCACTGAGGATGTCAACTGTGCTTTTGAGTTCCTGCTGAAGCTCACCCCCT
TGTTGGACAAAGCTGACCAGCGCTGCAACTGTGACTGTACAAACTTCCTGCTCCAAGAATGTGGCAAGCAGGGGCTTCTGTCTGAGGCCA
GCGTCAACAACCTTATGGCTAAGCGCAAAGCGGACCGAGAGCACGCACCCCAGCAGAAATCGGGAGAGAATGCCAACATCCAGCCCAACA
TCCAGCTGATCCTCCGGGCGGAGCCCACTGTCACAAACATCCTCAAGACGATGGATGCAGACCACTCTAAGTCACCGGAGGGACTGCTGG
GAGTCCTGGGCCACATGCTGTCCGGGAAGAGTCTGGACTTGCTGCTGGCTGCCGCCGCCGCCACTGGAAAGCTGAAATCCTTCGCCCGGA
AATTCATCAATTTGAATGAATTCACAACCTATGGCAGCGAAGAAAGCACCAAACCGGCCTCCGTCCGGGCCCTGCTGTTTGACATCTCCT
TCCTCATGCTGTGCCATGTGGCCCAGACCTATGGTTCAGAGGTGATTCTGTCCGAGTCGCGCACAGGAGCTGAGGTGCCCTTCTTCGAGA
CCTGGATGCAGACCTGCATGCCTGAGGAGGGCAAGATCCTGAACCCTGACCACCCCTGCTTCCGCCCCGACTCCACCAAAGTGGAGTCCC
TGGTGGCCCTGCTCAACAACTCCTCGGAGATGAAGCTAGTGCAGATGAAGTGGCATGAGGCCTGTCTCAGCATCTCAGCCGCCATCTTGG
AAATCCTCAATGCCTGGGAGAATGGGGTCCTGGCCTTCGAGTCCATCCAGAAAATCACTGATAACATCAAAGGGAAGGTATGCAGTCTGG
CGGTGTGTGCTGTGGCTTGGCTTGTGGCCCACGTCCGGATGCTGGGGCTGGATGAGCGTGAGAAGTCGCTGCAGATGATCCGCCAGCTGG
CAGGGCCACTGTTTAGTGAGAACACCCTGCAGTTCTACAATGAGAGGGTGGTGATCATGAACTCGATCCTGGAGCGCATGTGTGCCGACG
TGCTGCAGCAGACAGCCACGCAGATCAAGTTTCCCTCCACCGGGGTGGACACAATGCCCTACTGGAACCTGCTGCCCCCCAAGCGGCCCA
TCAAAGAGGTGCTGACGGACATTTTTGCCAAGGTGCTGGAGAAGGGCTGGGTGGACAGCCGCTCCATCCACATCTTTGACACCCTGCTGC
ACATGGGCGGCGTCTACTGGTTCTGCAACAACCTGATTAAGGAGCTGCTGAAGGAGACGCGGAAGGAGCACACGCTGCGGGCAGTGGAGC
TGCTCTACTCCATCTTCTGCCTGGACATGCAGCAAGTGACCCTGGTCCTGCTGGGCCACATCCTACCTGGCCTGCTCACTGACTCCTCCA
AGTGGCACAGCCTCATGGACCCCCCGGGCACTGCTCTTGCCAAGCTGGCCGTGTGGTGTGCCCTCAGTTCCTACTCCTCCCACAAGGGAC
AGGCGTCCACCCGCCAGAAGAAGAGACACCGCGAAGACATTGAGGATTATATCAGCCTCTTCCCCCTGGACGATGTGCAGCCTTCGAAGT
TGATGCGACTGCTGAGCTCTAATGAGGACGATGCCAACATCCTTTCGAGCCCCACAGACCGATCCATGAGCAGCTCCCTCTCAGCCTCTC
AGCTCCACACGGTCAACATGCGGGACCCTCTGAACCGAGTCCTGGCCAACCTGTTCCTGCTCATCTCCTCCATCCTGGGGTCTCGCACCG
CTGGCCCCCACACCCAGTTCGTGCAGTGGTTCATGGAGGAGTGTGTGGACTGCCTGGAGCAGGGTGGCCGTGGCAGCGTCCTGCAGTTCA
TGCCCTTCACCACCGTGTCGGAACTGGTGAAGGTGTCAGCCATGTCCAGCCCCAAGGTGGTTCTGGCCATCACGGACCTCAGCCTGCCCC
TGGGCCGCCAGGTGGCTGCTAAAGCCATTGCTGCACTCTGAGGGGCTTGGCATGGCCGCAGTGGGGGCTGGGGACTGGCGCAGCCCCAGG
CGCCTCCAAGGGAAGCAGTGAGGAAAGATGAGGCATCGTGCCTCACATCCGCTCCACATGGTGCAAGAGCCTCTAGCGGCTTCCAGTTCC
CCGCTCCTGACTCCTGACCTCCAGGATGTCTCCCGGTTTCTTCTTTCAAAATTTCCTCTCCATCTGCTGGCACCTGAGGAGAGTGAGCAG
CCTGGACCACAAGCCCAGTGGTCACCCCTGTGTGCGCCCGCCCCAGCCCAGGAGTAGTCTTACCTCTGAGGAACTTTCTAGATGCAAAGT
GTGTATGTGTGTGTGTGTGTGTGTGTGTGTGTGTTTGTGTGTATTTTGTAATATGTGAGGGAAATCTACCTTCGTTCATGTATAAATAAA

>88692_88692_2_TADA2A-MED24_TADA2A_chr17_35802753_ENST00000394395_MED24_chr17_38192407_ENST00000394126_length(amino acids)=1095AA_BP=177
MDRLGPFSNDPSDKPPCRGCSSYLMEPYIKCAECGPPPFFLCLQCFTRGFEYKKHQSDHTYEIMTSDFPVLDPSWTAQEEMALLEAVMDC
GFGNWQDVANQMCTKTKEECEKHYMKHFINNPLFASTLLNLKQAEEAKTADTAIPFHSTDDPPRPTFDSLLSRDMAGYMPARADFIEMVS
YSSVLTAISKFDDFSRDLCVQALLDIMDMFCDRLSCHGKAEECIGLCRALLSALHWLLRCTAASAERLREGLEAGTPAAGEKQLAMCLQR
LEKTLSSTKNRALLHIAKLEEASSWTAIEHSLLKLGEILANLSNPQLRSQAEQCGTLIRSIPTMLSVHAEQMHKTGFPTVHAVILLEGTM
NLTGETQSLVEQLTMVKRMQHIPTPLFVLEIWKACFVGLIESPEGTEELKWTAFTFLKIPQVLVKLKKYSHGDKDFTEDVNCAFEFLLKL
TPLLDKADQRCNCDCTNFLLQECGKQGLLSEASVNNLMAKRKADREHAPQQKSGENANIQPNIQLILRAEPTVTNILKTMDADHSKSPEG
LLGVLGHMLSGKSLDLLLAAAAATGKLKSFARKFINLNEFTTYGSEESTKPASVRALLFDISFLMLCHVAQTYGSEVILSESRTGAEVPF
FETWMQTCMPEEGKILNPDHPCFRPDSTKVESLVALLNNSSEMKLVQMKWHEACLSISAAILEILNAWENGVLAFESIQKITDNIKGKVC
SLAVCAVAWLVAHVRMLGLDEREKSLQMIRQLAGPLFSENTLQFYNERVVIMNSILERMCADVLQQTATQIKFPSTGVDTMPYWNLLPPK
RPIKEVLTDIFAKVLEKGWVDSRSIHIFDTLLHMGGVYWFCNNLIKELLKETRKEHTLRAVELLYSIFCLDMQQVTLVLLGHILPGLLTD
SSKWHSLMDPPGTALAKLAVWCALSSYSSHKGQASTRQKKRHREDIEDYISLFPLDDVQPSKLMRLLSSNEDDANILSSPTDRSMSSSLS
ASQLHTVNMRDPLNRVLANLFLLISSILGSRTAGPHTQFVQWFMEECVDCLEQGGRGSVLQFMPFTTVSELVKVSAMSSPKVVLAITDLS

--------------------------------------------------------------
>88692_88692_3_TADA2A-MED24_TADA2A_chr17_35802753_ENST00000417170_MED24_chr17_38192407_ENST00000394126_length(transcript)=4089nt_BP=900nt
TTTCCCGCTCAGCCCTGGAGCGCGTAGCTCTACCAAGAATGGCCACTGTGCCAGATGCCCCTGACCAGCGTTGCCCATTTGAATTTCCTA
GCAGGCCCCCCAAAGTAGGTATTTCAGTACCCTGTTAGAGCTGAGGCGCAGGTAAAATGACTGGCCCAGGCCGGTCCCACCCCGTAAGGA
TTTGAACGTTGGCTCCACAACTCGGGAGCCTGCGCCTTTCCTCCTCCCAACGTGGACTCCTGCCCGGCGAAGTGCCTCACTTCCTTCTCC
CGGGAGTCATCAAGCTTTGGTGTATGTGTTGGCCGGTTCTGAAGTCTTGAAGAAGCTCTGCTGAGGAAGACCAAAGCAGCACTCGTTGCC
AATTAGGGAATGGACCGTTTGGGTCCCTTTAGCAATGATCCCTCTGATAAGCCACCTTGCCGAGGCTGCTCCTCCTACCTCATGGAGCCT
TATATCAAGTGTGCTGAATGTGGGCCACCTCCTTTTTTCCTCTGCTTGCAGTGTTTCACTCGAGGCTTTGAGTACAAGAAACATCAAAGC
GATCATACTTATGAAATAATGACTTCAGATTTTCCTGTCCTTGATCCCAGCTGGACTGCTCAAGAAGAAATGGCCCTTTTAGAAGCTGTG
ATGGACTGTGGCTTTGGAAATTGGCAGGATGTAGCCAATCAAATGTGCACCAAGACCAAGGAGGAGTGTGAGAAGCACTATATGAAGCAT
TTCATCAATAACCCTCTGTTTGCATCTACCCTGCTGAACCTGAAACAAGCAGAGGAAGCAAAAACTGCTGACACAGCCATTCCATTTCAC
TCTACAGATGACCCTCCCCGACCTACCTTTGACTCCTTGCTTTCTCGGGACATGGCCGGGTACATGCCAGCTCGAGCAGATTTCATTGAG
ATGGTGTCCTACTCTTCTGTCCTCACAGCCATCAGTAAGTTTGATGACTTTTCTCGGGACCTGTGTGTCCAGGCATTGCTGGACATCATG
GACATGTTTTGTGACCGTCTGAGCTGTCACGGCAAAGCAGAGGAATGCATCGGACTGTGCCGAGCCCTTCTTAGCGCCCTCCACTGGCTG
CTGCGCTGCACGGCAGCCTCTGCAGAGCGGCTGCGGGAGGGGCTGGAGGCCGGCACTCCAGCCGCTGGGGAGAAGCAGCTTGCCATGTGC
CTTCAGCGCCTGGAGAAAACCCTCAGCAGCACCAAGAACCGGGCCCTGCTGCACATCGCCAAACTAGAGGAGGCCTCTTCTTGGACTGCC
ATCGAGCATTCTCTCTTGAAACTTGGAGAGATCCTGGCCAATCTCAGCAACCCGCAGCTCCGGAGTCAGGCCGAGCAGTGTGGCACCCTC
ATTAGGAGCATCCCCACGATGCTGTCTGTGCATGCGGAGCAGATGCACAAGACCGGCTTCCCCACTGTCCACGCCGTGATCCTGCTCGAG
GGCACCATGAACCTGACAGGCGAGACGCAGTCCCTGGTGGAGCAGCTGACGATGGTGAAGCGCATGCAGCATATCCCCACCCCACTTTTT
GTCCTGGAGATCTGGAAAGCTTGCTTCGTGGGGCTCATTGAGTCTCCCGAGGGTACGGAGGAGCTCAAGTGGACAGCTTTCACTTTCCTC
AAGATTCCACAGGTTTTGGTGAAGTTGAAGAAGTACTCTCATGGAGACAAGGACTTCACTGAGGATGTCAACTGTGCTTTTGAGTTCCTG
CTGAAGCTCACCCCCTTGTTGGACAAAGCTGACCAGCGCTGCAACTGTGACTGTACAAACTTCCTGCTCCAAGAATGTGGCAAGCAGGGG
CTTCTGTCTGAGGCCAGCGTCAACAACCTTATGGCTAAGCGCAAAGCGGACCGAGAGCACGCACCCCAGCAGAAATCGGGAGAGAATGCC
AACATCCAGCCCAACATCCAGCTGATCCTCCGGGCGGAGCCCACTGTCACAAACATCCTCAAGACGATGGATGCAGACCACTCTAAGTCA
CCGGAGGGACTGCTGGGAGTCCTGGGCCACATGCTGTCCGGGAAGAGTCTGGACTTGCTGCTGGCTGCCGCCGCCGCCACTGGAAAGCTG
AAATCCTTCGCCCGGAAATTCATCAATTTGAATGAATTCACAACCTATGGCAGCGAAGAAAGCACCAAACCGGCCTCCGTCCGGGCCCTG
CTGTTTGACATCTCCTTCCTCATGCTGTGCCATGTGGCCCAGACCTATGGTTCAGAGGTGATTCTGTCCGAGTCGCGCACAGGAGCTGAG
GTGCCCTTCTTCGAGACCTGGATGCAGACCTGCATGCCTGAGGAGGGCAAGATCCTGAACCCTGACCACCCCTGCTTCCGCCCCGACTCC
ACCAAAGTGGAGTCCCTGGTGGCCCTGCTCAACAACTCCTCGGAGATGAAGCTAGTGCAGATGAAGTGGCATGAGGCCTGTCTCAGCATC
TCAGCCGCCATCTTGGAAATCCTCAATGCCTGGGAGAATGGGGTCCTGGCCTTCGAGTCCATCCAGAAAATCACTGATAACATCAAAGGG
AAGGTATGCAGTCTGGCGGTGTGTGCTGTGGCTTGGCTTGTGGCCCACGTCCGGATGCTGGGGCTGGATGAGCGTGAGAAGTCGCTGCAG
ATGATCCGCCAGCTGGCAGGGCCACTGTTTAGTGAGAACACCCTGCAGTTCTACAATGAGAGGGTGGTGATCATGAACTCGATCCTGGAG
CGCATGTGTGCCGACGTGCTGCAGCAGACAGCCACGCAGATCAAGTTTCCCTCCACCGGGGTGGACACAATGCCCTACTGGAACCTGCTG
CCCCCCAAGCGGCCCATCAAAGAGGTGCTGACGGACATTTTTGCCAAGGTGCTGGAGAAGGGCTGGGTGGACAGCCGCTCCATCCACATC
TTTGACACCCTGCTGCACATGGGCGGCGTCTACTGGTTCTGCAACAACCTGATTAAGGAGCTGCTGAAGGAGACGCGGAAGGAGCACACG
CTGCGGGCAGTGGAGCTGCTCTACTCCATCTTCTGCCTGGACATGCAGCAAGTGACCCTGGTCCTGCTGGGCCACATCCTACCTGGCCTG
CTCACTGACTCCTCCAAGTGGCACAGCCTCATGGACCCCCCGGGCACTGCTCTTGCCAAGCTGGCCGTGTGGTGTGCCCTCAGTTCCTAC
TCCTCCCACAAGGGACAGGCGTCCACCCGCCAGAAGAAGAGACACCGCGAAGACATTGAGGATTATATCAGCCTCTTCCCCCTGGACGAT
GTGCAGCCTTCGAAGTTGATGCGACTGCTGAGCTCTAATGAGGACGATGCCAACATCCTTTCGAGCCCCACAGACCGATCCATGAGCAGC
TCCCTCTCAGCCTCTCAGCTCCACACGGTCAACATGCGGGACCCTCTGAACCGAGTCCTGGCCAACCTGTTCCTGCTCATCTCCTCCATC
CTGGGGTCTCGCACCGCTGGCCCCCACACCCAGTTCGTGCAGTGGTTCATGGAGGAGTGTGTGGACTGCCTGGAGCAGGGTGGCCGTGGC
AGCGTCCTGCAGTTCATGCCCTTCACCACCGTGTCGGAACTGGTGAAGGTGTCAGCCATGTCCAGCCCCAAGGTGGTTCTGGCCATCACG
GACCTCAGCCTGCCCCTGGGCCGCCAGGTGGCTGCTAAAGCCATTGCTGCACTCTGAGGGGCTTGGCATGGCCGCAGTGGGGGCTGGGGA
CTGGCGCAGCCCCAGGCGCCTCCAAGGGAAGCAGTGAGGAAAGATGAGGCATCGTGCCTCACATCCGCTCCACATGGTGCAAGAGCCTCT
AGCGGCTTCCAGTTCCCCGCTCCTGACTCCTGACCTCCAGGATGTCTCCCGGTTTCTTCTTTCAAAATTTCCTCTCCATCTGCTGGCACC
TGAGGAGAGTGAGCAGCCTGGACCACAAGCCCAGTGGTCACCCCTGTGTGCGCCCGCCCCAGCCCAGGAGTAGTCTTACCTCTGAGGAAC
TTTCTAGATGCAAAGTGTGTATGTGTGTGTGTGTGTGTGTGTGTGTGTGTTTGTGTGTATTTTGTAATATGTGAGGGAAATCTACCTTCG

>88692_88692_3_TADA2A-MED24_TADA2A_chr17_35802753_ENST00000417170_MED24_chr17_38192407_ENST00000394126_length(amino acids)=1095AA_BP=177
MDRLGPFSNDPSDKPPCRGCSSYLMEPYIKCAECGPPPFFLCLQCFTRGFEYKKHQSDHTYEIMTSDFPVLDPSWTAQEEMALLEAVMDC
GFGNWQDVANQMCTKTKEECEKHYMKHFINNPLFASTLLNLKQAEEAKTADTAIPFHSTDDPPRPTFDSLLSRDMAGYMPARADFIEMVS
YSSVLTAISKFDDFSRDLCVQALLDIMDMFCDRLSCHGKAEECIGLCRALLSALHWLLRCTAASAERLREGLEAGTPAAGEKQLAMCLQR
LEKTLSSTKNRALLHIAKLEEASSWTAIEHSLLKLGEILANLSNPQLRSQAEQCGTLIRSIPTMLSVHAEQMHKTGFPTVHAVILLEGTM
NLTGETQSLVEQLTMVKRMQHIPTPLFVLEIWKACFVGLIESPEGTEELKWTAFTFLKIPQVLVKLKKYSHGDKDFTEDVNCAFEFLLKL
TPLLDKADQRCNCDCTNFLLQECGKQGLLSEASVNNLMAKRKADREHAPQQKSGENANIQPNIQLILRAEPTVTNILKTMDADHSKSPEG
LLGVLGHMLSGKSLDLLLAAAAATGKLKSFARKFINLNEFTTYGSEESTKPASVRALLFDISFLMLCHVAQTYGSEVILSESRTGAEVPF
FETWMQTCMPEEGKILNPDHPCFRPDSTKVESLVALLNNSSEMKLVQMKWHEACLSISAAILEILNAWENGVLAFESIQKITDNIKGKVC
SLAVCAVAWLVAHVRMLGLDEREKSLQMIRQLAGPLFSENTLQFYNERVVIMNSILERMCADVLQQTATQIKFPSTGVDTMPYWNLLPPK
RPIKEVLTDIFAKVLEKGWVDSRSIHIFDTLLHMGGVYWFCNNLIKELLKETRKEHTLRAVELLYSIFCLDMQQVTLVLLGHILPGLLTD
SSKWHSLMDPPGTALAKLAVWCALSSYSSHKGQASTRQKKRHREDIEDYISLFPLDDVQPSKLMRLLSSNEDDANILSSPTDRSMSSSLS
ASQLHTVNMRDPLNRVLANLFLLISSILGSRTAGPHTQFVQWFMEECVDCLEQGGRGSVLQFMPFTTVSELVKVSAMSSPKVVLAITDLS

--------------------------------------------------------------
>88692_88692_4_TADA2A-MED24_TADA2A_chr17_35802753_ENST00000586023_MED24_chr17_38192407_ENST00000394126_length(transcript)=3828nt_BP=639nt
GTCTCGGCGAGGGAGTCATCAAGCTTTGGTGTATGTGTTGGCCGGTTCTGAAGTCTTGAAGAAGCTCTGCTGAGGAAGACCAAAGCAGCA
CTCGTTGCCAATTAGGGAATGGACCGTTTGGGTCCCTTTAGCAATGATCCCTCTGATAAGCCACCTTGCCGAGGCTGCTCCTCCTACCTC
ATGGAGCCTTATATCAAGTGTGCTGAATGTGGGCCACCTCCTTTTTTCCTCTGCTTGCAGTGTTTCACTCGAGGCTTTGAGTACAAGAAA
CATCAAAGCGATCATACTTATGAAATAATGACTTCAGATTTTCCTGTCCTTGATCCCAGCTGGACTGCTCAAGAAGAAATGGCCCTTTTA
GAAGCTGTGATGGACTGTGGCTTTGGAAATTGGCAGGATGTAGCCAATCAAATGTGCACCAAGACCAAGGAGGAGTGTGAGAAGCACTAT
ATGAAGCATTTCATCAATAACCCTCTGTTTGCATCTACCCTGCTGAACCTGAAACAAGCAGAGGAAGCAAAAACTGCTGACACAGCCATT
CCATTTCACTCTACAGATGACCCTCCCCGACCTACCTTTGACTCCTTGCTTTCTCGGGACATGGCCGGGTACATGCCAGCTCGAGCAGAT
TTCATTGAGATGGTGTCCTACTCTTCTGTCCTCACAGCCATCAGTAAGTTTGATGACTTTTCTCGGGACCTGTGTGTCCAGGCATTGCTG
GACATCATGGACATGTTTTGTGACCGTCTGAGCTGTCACGGCAAAGCAGAGGAATGCATCGGACTGTGCCGAGCCCTTCTTAGCGCCCTC
CACTGGCTGCTGCGCTGCACGGCAGCCTCTGCAGAGCGGCTGCGGGAGGGGCTGGAGGCCGGCACTCCAGCCGCTGGGGAGAAGCAGCTT
GCCATGTGCCTTCAGCGCCTGGAGAAAACCCTCAGCAGCACCAAGAACCGGGCCCTGCTGCACATCGCCAAACTAGAGGAGGCCTCTTCT
TGGACTGCCATCGAGCATTCTCTCTTGAAACTTGGAGAGATCCTGGCCAATCTCAGCAACCCGCAGCTCCGGAGTCAGGCCGAGCAGTGT
GGCACCCTCATTAGGAGCATCCCCACGATGCTGTCTGTGCATGCGGAGCAGATGCACAAGACCGGCTTCCCCACTGTCCACGCCGTGATC
CTGCTCGAGGGCACCATGAACCTGACAGGCGAGACGCAGTCCCTGGTGGAGCAGCTGACGATGGTGAAGCGCATGCAGCATATCCCCACC
CCACTTTTTGTCCTGGAGATCTGGAAAGCTTGCTTCGTGGGGCTCATTGAGTCTCCCGAGGGTACGGAGGAGCTCAAGTGGACAGCTTTC
ACTTTCCTCAAGATTCCACAGGTTTTGGTGAAGTTGAAGAAGTACTCTCATGGAGACAAGGACTTCACTGAGGATGTCAACTGTGCTTTT
GAGTTCCTGCTGAAGCTCACCCCCTTGTTGGACAAAGCTGACCAGCGCTGCAACTGTGACTGTACAAACTTCCTGCTCCAAGAATGTGGC
AAGCAGGGGCTTCTGTCTGAGGCCAGCGTCAACAACCTTATGGCTAAGCGCAAAGCGGACCGAGAGCACGCACCCCAGCAGAAATCGGGA
GAGAATGCCAACATCCAGCCCAACATCCAGCTGATCCTCCGGGCGGAGCCCACTGTCACAAACATCCTCAAGACGATGGATGCAGACCAC
TCTAAGTCACCGGAGGGACTGCTGGGAGTCCTGGGCCACATGCTGTCCGGGAAGAGTCTGGACTTGCTGCTGGCTGCCGCCGCCGCCACT
GGAAAGCTGAAATCCTTCGCCCGGAAATTCATCAATTTGAATGAATTCACAACCTATGGCAGCGAAGAAAGCACCAAACCGGCCTCCGTC
CGGGCCCTGCTGTTTGACATCTCCTTCCTCATGCTGTGCCATGTGGCCCAGACCTATGGTTCAGAGGTGATTCTGTCCGAGTCGCGCACA
GGAGCTGAGGTGCCCTTCTTCGAGACCTGGATGCAGACCTGCATGCCTGAGGAGGGCAAGATCCTGAACCCTGACCACCCCTGCTTCCGC
CCCGACTCCACCAAAGTGGAGTCCCTGGTGGCCCTGCTCAACAACTCCTCGGAGATGAAGCTAGTGCAGATGAAGTGGCATGAGGCCTGT
CTCAGCATCTCAGCCGCCATCTTGGAAATCCTCAATGCCTGGGAGAATGGGGTCCTGGCCTTCGAGTCCATCCAGAAAATCACTGATAAC
ATCAAAGGGAAGGTATGCAGTCTGGCGGTGTGTGCTGTGGCTTGGCTTGTGGCCCACGTCCGGATGCTGGGGCTGGATGAGCGTGAGAAG
TCGCTGCAGATGATCCGCCAGCTGGCAGGGCCACTGTTTAGTGAGAACACCCTGCAGTTCTACAATGAGAGGGTGGTGATCATGAACTCG
ATCCTGGAGCGCATGTGTGCCGACGTGCTGCAGCAGACAGCCACGCAGATCAAGTTTCCCTCCACCGGGGTGGACACAATGCCCTACTGG
AACCTGCTGCCCCCCAAGCGGCCCATCAAAGAGGTGCTGACGGACATTTTTGCCAAGGTGCTGGAGAAGGGCTGGGTGGACAGCCGCTCC
ATCCACATCTTTGACACCCTGCTGCACATGGGCGGCGTCTACTGGTTCTGCAACAACCTGATTAAGGAGCTGCTGAAGGAGACGCGGAAG
GAGCACACGCTGCGGGCAGTGGAGCTGCTCTACTCCATCTTCTGCCTGGACATGCAGCAAGTGACCCTGGTCCTGCTGGGCCACATCCTA
CCTGGCCTGCTCACTGACTCCTCCAAGTGGCACAGCCTCATGGACCCCCCGGGCACTGCTCTTGCCAAGCTGGCCGTGTGGTGTGCCCTC
AGTTCCTACTCCTCCCACAAGGGACAGGCGTCCACCCGCCAGAAGAAGAGACACCGCGAAGACATTGAGGATTATATCAGCCTCTTCCCC
CTGGACGATGTGCAGCCTTCGAAGTTGATGCGACTGCTGAGCTCTAATGAGGACGATGCCAACATCCTTTCGAGCCCCACAGACCGATCC
ATGAGCAGCTCCCTCTCAGCCTCTCAGCTCCACACGGTCAACATGCGGGACCCTCTGAACCGAGTCCTGGCCAACCTGTTCCTGCTCATC
TCCTCCATCCTGGGGTCTCGCACCGCTGGCCCCCACACCCAGTTCGTGCAGTGGTTCATGGAGGAGTGTGTGGACTGCCTGGAGCAGGGT
GGCCGTGGCAGCGTCCTGCAGTTCATGCCCTTCACCACCGTGTCGGAACTGGTGAAGGTGTCAGCCATGTCCAGCCCCAAGGTGGTTCTG
GCCATCACGGACCTCAGCCTGCCCCTGGGCCGCCAGGTGGCTGCTAAAGCCATTGCTGCACTCTGAGGGGCTTGGCATGGCCGCAGTGGG
GGCTGGGGACTGGCGCAGCCCCAGGCGCCTCCAAGGGAAGCAGTGAGGAAAGATGAGGCATCGTGCCTCACATCCGCTCCACATGGTGCA
AGAGCCTCTAGCGGCTTCCAGTTCCCCGCTCCTGACTCCTGACCTCCAGGATGTCTCCCGGTTTCTTCTTTCAAAATTTCCTCTCCATCT
GCTGGCACCTGAGGAGAGTGAGCAGCCTGGACCACAAGCCCAGTGGTCACCCCTGTGTGCGCCCGCCCCAGCCCAGGAGTAGTCTTACCT
CTGAGGAACTTTCTAGATGCAAAGTGTGTATGTGTGTGTGTGTGTGTGTGTGTGTGTGTTTGTGTGTATTTTGTAATATGTGAGGGAAAT

>88692_88692_4_TADA2A-MED24_TADA2A_chr17_35802753_ENST00000586023_MED24_chr17_38192407_ENST00000394126_length(amino acids)=1095AA_BP=177
MDRLGPFSNDPSDKPPCRGCSSYLMEPYIKCAECGPPPFFLCLQCFTRGFEYKKHQSDHTYEIMTSDFPVLDPSWTAQEEMALLEAVMDC
GFGNWQDVANQMCTKTKEECEKHYMKHFINNPLFASTLLNLKQAEEAKTADTAIPFHSTDDPPRPTFDSLLSRDMAGYMPARADFIEMVS
YSSVLTAISKFDDFSRDLCVQALLDIMDMFCDRLSCHGKAEECIGLCRALLSALHWLLRCTAASAERLREGLEAGTPAAGEKQLAMCLQR
LEKTLSSTKNRALLHIAKLEEASSWTAIEHSLLKLGEILANLSNPQLRSQAEQCGTLIRSIPTMLSVHAEQMHKTGFPTVHAVILLEGTM
NLTGETQSLVEQLTMVKRMQHIPTPLFVLEIWKACFVGLIESPEGTEELKWTAFTFLKIPQVLVKLKKYSHGDKDFTEDVNCAFEFLLKL
TPLLDKADQRCNCDCTNFLLQECGKQGLLSEASVNNLMAKRKADREHAPQQKSGENANIQPNIQLILRAEPTVTNILKTMDADHSKSPEG
LLGVLGHMLSGKSLDLLLAAAAATGKLKSFARKFINLNEFTTYGSEESTKPASVRALLFDISFLMLCHVAQTYGSEVILSESRTGAEVPF
FETWMQTCMPEEGKILNPDHPCFRPDSTKVESLVALLNNSSEMKLVQMKWHEACLSISAAILEILNAWENGVLAFESIQKITDNIKGKVC
SLAVCAVAWLVAHVRMLGLDEREKSLQMIRQLAGPLFSENTLQFYNERVVIMNSILERMCADVLQQTATQIKFPSTGVDTMPYWNLLPPK
RPIKEVLTDIFAKVLEKGWVDSRSIHIFDTLLHMGGVYWFCNNLIKELLKETRKEHTLRAVELLYSIFCLDMQQVTLVLLGHILPGLLTD
SSKWHSLMDPPGTALAKLAVWCALSSYSSHKGQASTRQKKRHREDIEDYISLFPLDDVQPSKLMRLLSSNEDDANILSSPTDRSMSSSLS
ASQLHTVNMRDPLNRVLANLFLLISSILGSRTAGPHTQFVQWFMEECVDCLEQGGRGSVLQFMPFTTVSELVKVSAMSSPKVVLAITDLS

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Fusion Gene PPI Analysis for TADA2A-MED24


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for TADA2A-MED24


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for TADA2A-MED24


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource