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	Fusion Gene Summary
	Fusion Gene ORF analysis
	Fusion Genomic Features
	Fusion Protein Features
	Fusion Gene Sequence
	Fusion Gene PPI analysis
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Fusion gene:TAPBP-DOCK1 (FusionGDB2 ID:89072)

Fusion Gene Summary for TAPBP-DOCK1

Fusion gene summary

Fusion gene information	Fusion gene name: TAPBP-DOCK1
	Fusion gene ID: 89072
		Hgene	Tgene
	Gene symbol	TAPBP	DOCK1
	Gene ID	6892	1793
	Gene name	TAP binding protein	dedicator of cytokinesis 1
	Synonyms	NGS17\|TAPA\|TPN\|TPSN	DOCK180\|ced5
	Cytomap	6p21.32	10q26.2
	Type of gene	protein-coding	protein-coding
	Description	tapasinNGS-17TAP binding protein (tapasin)TAP-associated protein	dedicator of cytokinesis protein 1180 kDa protein downstream of CRKDOwnstream of CrK
	Modification date	20200313	20200327
	UniProtAcc	.	Q5JSL3
	Ensembl transtripts involved in fusion gene	ENST00000426633, ENST00000434618, ENST00000456592, ENST00000475304, ENST00000374568, ENST00000374572, ENST00000383065, ENST00000383066, ENST00000383067, ENST00000383197, ENST00000383198, ENST00000395114, ENST00000412144, ENST00000417059, ENST00000437315, ENST00000456807, ENST00000461837, ENST00000467834, ENST00000480059, ENST00000489157, ENST00000495024, ENST00000546700, ENST00000548408, ENST00000549142, ENST00000549949, ENST00000550330, ENST00000550794, ENST00000550915, ENST00000551943, ENST00000552779, ENST00000553235,	ENST00000484400, ENST00000280333,
Fusion gene scores	* DoF score	6 X 6 X 3=108	16 X 15 X 8=1920
	# samples	7	16
	** MAII score	log2(7/108*10)=-0.625604485218502 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0	log2(16/1920*10)=-3.58496250072116 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0
Context	PubMed: TAPBP [Title/Abstract] AND DOCK1 [Title/Abstract] AND fusion [Title/Abstract]
Most frequent breakpoint	TAPBP(33280993)-DOCK1(128768965), # samples:1
Anticipated loss of major functional domain due to fusion event.

* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Partner	Gene	GO ID	GO term	PubMed ID
Hgene	TAPBP	GO:0061635	regulation of protein complex stability	18802093
Hgene	TAPBP	GO:0065003	protein-containing complex assembly	17947644

Fusion gene breakpoints across TAPBP (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion gene breakpoints across DOCK1 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

Source	Disease	Sample	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
ChimerDB4	BRCA	TCGA-AR-A2LK	TAPBP	chr6	33280993	-	DOCK1	chr10	128768965	+

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Fusion Gene ORF analysis for TAPBP-DOCK1

Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

ORF	Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
5CDS-intron	ENST00000426633	ENST00000484400	TAPBP	chr6	33280993	-	DOCK1	chr10	128768965	+
5CDS-intron	ENST00000434618	ENST00000484400	TAPBP	chr6	33280993	-	DOCK1	chr10	128768965	+
5CDS-intron	ENST00000456592	ENST00000484400	TAPBP	chr6	33280993	-	DOCK1	chr10	128768965	+
5CDS-intron	ENST00000475304	ENST00000484400	TAPBP	chr6	33280993	-	DOCK1	chr10	128768965	+
In-frame	ENST00000426633	ENST00000280333	TAPBP	chr6	33280993	-	DOCK1	chr10	128768965	+
In-frame	ENST00000434618	ENST00000280333	TAPBP	chr6	33280993	-	DOCK1	chr10	128768965	+
In-frame	ENST00000456592	ENST00000280333	TAPBP	chr6	33280993	-	DOCK1	chr10	128768965	+
In-frame	ENST00000475304	ENST00000280333	TAPBP	chr6	33280993	-	DOCK1	chr10	128768965	+
intron-3CDS	ENST00000374568	ENST00000280333	TAPBP	chr6	33280993	-	DOCK1	chr10	128768965	+
intron-3CDS	ENST00000374572	ENST00000280333	TAPBP	chr6	33280993	-	DOCK1	chr10	128768965	+
intron-3CDS	ENST00000383065	ENST00000280333	TAPBP	chr6	33280993	-	DOCK1	chr10	128768965	+
intron-3CDS	ENST00000383066	ENST00000280333	TAPBP	chr6	33280993	-	DOCK1	chr10	128768965	+
intron-3CDS	ENST00000383067	ENST00000280333	TAPBP	chr6	33280993	-	DOCK1	chr10	128768965	+
intron-3CDS	ENST00000383197	ENST00000280333	TAPBP	chr6	33280993	-	DOCK1	chr10	128768965	+
intron-3CDS	ENST00000383198	ENST00000280333	TAPBP	chr6	33280993	-	DOCK1	chr10	128768965	+
intron-3CDS	ENST00000395114	ENST00000280333	TAPBP	chr6	33280993	-	DOCK1	chr10	128768965	+
intron-3CDS	ENST00000412144	ENST00000280333	TAPBP	chr6	33280993	-	DOCK1	chr10	128768965	+
intron-3CDS	ENST00000417059	ENST00000280333	TAPBP	chr6	33280993	-	DOCK1	chr10	128768965	+
intron-3CDS	ENST00000437315	ENST00000280333	TAPBP	chr6	33280993	-	DOCK1	chr10	128768965	+
intron-3CDS	ENST00000456807	ENST00000280333	TAPBP	chr6	33280993	-	DOCK1	chr10	128768965	+
intron-3CDS	ENST00000461837	ENST00000280333	TAPBP	chr6	33280993	-	DOCK1	chr10	128768965	+
intron-3CDS	ENST00000467834	ENST00000280333	TAPBP	chr6	33280993	-	DOCK1	chr10	128768965	+
intron-3CDS	ENST00000480059	ENST00000280333	TAPBP	chr6	33280993	-	DOCK1	chr10	128768965	+
intron-3CDS	ENST00000489157	ENST00000280333	TAPBP	chr6	33280993	-	DOCK1	chr10	128768965	+
intron-3CDS	ENST00000495024	ENST00000280333	TAPBP	chr6	33280993	-	DOCK1	chr10	128768965	+
intron-3CDS	ENST00000546700	ENST00000280333	TAPBP	chr6	33280993	-	DOCK1	chr10	128768965	+
intron-3CDS	ENST00000548408	ENST00000280333	TAPBP	chr6	33280993	-	DOCK1	chr10	128768965	+
intron-3CDS	ENST00000549142	ENST00000280333	TAPBP	chr6	33280993	-	DOCK1	chr10	128768965	+
intron-3CDS	ENST00000549949	ENST00000280333	TAPBP	chr6	33280993	-	DOCK1	chr10	128768965	+
intron-3CDS	ENST00000550330	ENST00000280333	TAPBP	chr6	33280993	-	DOCK1	chr10	128768965	+
intron-3CDS	ENST00000550794	ENST00000280333	TAPBP	chr6	33280993	-	DOCK1	chr10	128768965	+
intron-3CDS	ENST00000550915	ENST00000280333	TAPBP	chr6	33280993	-	DOCK1	chr10	128768965	+
intron-3CDS	ENST00000551943	ENST00000280333	TAPBP	chr6	33280993	-	DOCK1	chr10	128768965	+
intron-3CDS	ENST00000552779	ENST00000280333	TAPBP	chr6	33280993	-	DOCK1	chr10	128768965	+
intron-3CDS	ENST00000553235	ENST00000280333	TAPBP	chr6	33280993	-	DOCK1	chr10	128768965	+
intron-intron	ENST00000374568	ENST00000484400	TAPBP	chr6	33280993	-	DOCK1	chr10	128768965	+
intron-intron	ENST00000374572	ENST00000484400	TAPBP	chr6	33280993	-	DOCK1	chr10	128768965	+
intron-intron	ENST00000383065	ENST00000484400	TAPBP	chr6	33280993	-	DOCK1	chr10	128768965	+
intron-intron	ENST00000383066	ENST00000484400	TAPBP	chr6	33280993	-	DOCK1	chr10	128768965	+
intron-intron	ENST00000383067	ENST00000484400	TAPBP	chr6	33280993	-	DOCK1	chr10	128768965	+
intron-intron	ENST00000383197	ENST00000484400	TAPBP	chr6	33280993	-	DOCK1	chr10	128768965	+
intron-intron	ENST00000383198	ENST00000484400	TAPBP	chr6	33280993	-	DOCK1	chr10	128768965	+
intron-intron	ENST00000395114	ENST00000484400	TAPBP	chr6	33280993	-	DOCK1	chr10	128768965	+
intron-intron	ENST00000412144	ENST00000484400	TAPBP	chr6	33280993	-	DOCK1	chr10	128768965	+
intron-intron	ENST00000417059	ENST00000484400	TAPBP	chr6	33280993	-	DOCK1	chr10	128768965	+
intron-intron	ENST00000437315	ENST00000484400	TAPBP	chr6	33280993	-	DOCK1	chr10	128768965	+
intron-intron	ENST00000456807	ENST00000484400	TAPBP	chr6	33280993	-	DOCK1	chr10	128768965	+
intron-intron	ENST00000461837	ENST00000484400	TAPBP	chr6	33280993	-	DOCK1	chr10	128768965	+
intron-intron	ENST00000467834	ENST00000484400	TAPBP	chr6	33280993	-	DOCK1	chr10	128768965	+
intron-intron	ENST00000480059	ENST00000484400	TAPBP	chr6	33280993	-	DOCK1	chr10	128768965	+
intron-intron	ENST00000489157	ENST00000484400	TAPBP	chr6	33280993	-	DOCK1	chr10	128768965	+
intron-intron	ENST00000495024	ENST00000484400	TAPBP	chr6	33280993	-	DOCK1	chr10	128768965	+
intron-intron	ENST00000546700	ENST00000484400	TAPBP	chr6	33280993	-	DOCK1	chr10	128768965	+
intron-intron	ENST00000548408	ENST00000484400	TAPBP	chr6	33280993	-	DOCK1	chr10	128768965	+
intron-intron	ENST00000549142	ENST00000484400	TAPBP	chr6	33280993	-	DOCK1	chr10	128768965	+
intron-intron	ENST00000549949	ENST00000484400	TAPBP	chr6	33280993	-	DOCK1	chr10	128768965	+
intron-intron	ENST00000550330	ENST00000484400	TAPBP	chr6	33280993	-	DOCK1	chr10	128768965	+
intron-intron	ENST00000550794	ENST00000484400	TAPBP	chr6	33280993	-	DOCK1	chr10	128768965	+
intron-intron	ENST00000550915	ENST00000484400	TAPBP	chr6	33280993	-	DOCK1	chr10	128768965	+
intron-intron	ENST00000551943	ENST00000484400	TAPBP	chr6	33280993	-	DOCK1	chr10	128768965	+
intron-intron	ENST00000552779	ENST00000484400	TAPBP	chr6	33280993	-	DOCK1	chr10	128768965	+
intron-intron	ENST00000553235	ENST00000484400	TAPBP	chr6	33280993	-	DOCK1	chr10	128768965	+

ORFfinder result based on the fusion transcript sequence of in-frame fusion genes.

Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	Seq length (transcript)	BP loci (transcript)	Predicted start (transcript)	Predicted stop (transcript)	Seq length (amino acids)
ENST00000434618	TAPBP	chr6	33280993	-	ENST00000280333	DOCK1	chr10	128768965	+	7457	815	346	6366	2006
ENST00000475304	TAPBP	chr6	33280993	-	ENST00000280333	DOCK1	chr10	128768965	+	7321	679	210	6230	2006
ENST00000426633	TAPBP	chr6	33280993	-	ENST00000280333	DOCK1	chr10	128768965	+	7282	640	171	6191	2006
ENST00000456592	TAPBP	chr6	33280993	-	ENST00000280333	DOCK1	chr10	128768965	+	7457	815	346	6366	2006

DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.

Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	No-coding score	Coding score
ENST00000434618	ENST00000280333	TAPBP	chr6	33280993	-	DOCK1	chr10	128768965	+	0.000866826	0.99913317
ENST00000475304	ENST00000280333	TAPBP	chr6	33280993	-	DOCK1	chr10	128768965	+	0.000816103	0.99918383
ENST00000426633	ENST00000280333	TAPBP	chr6	33280993	-	DOCK1	chr10	128768965	+	0.000809306	0.99919075
ENST00000456592	ENST00000280333	TAPBP	chr6	33280993	-	DOCK1	chr10	128768965	+	0.000866826	0.99913317

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Fusion Genomic Features for TAPBP-DOCK1

FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.

Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	1-p	p (fusion gene breakpoint)
TAPBP	chr6	33280993	-	DOCK1	chr10	128768965	+	9.03E-06	0.99999094
TAPBP	chr6	33280993	-	DOCK1	chr10	128768965	+	9.03E-06	0.99999094

Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.

Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for TAPBP-DOCK1

Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr6:33280993/chr10:128768965)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.

Main function of each fusion partner protein. (from UniProt)

Hgene	Tgene
.	DOCK1 Q5JSL3
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.	FUNCTION: Guanine nucleotide-exchange factor (GEF) that activates CDC42 by exchanging bound GDP for free GTP. Required for marginal zone (MZ) B-cell development, is associated with early bone marrow B-cell development, MZ B-cell formation, MZ B-cell number and marginal metallophilic macrophages morphology. Facilitates filopodia formation through the activation of CDC42. {ECO:0000250\|UniProtKB:A2AF47}.

Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at
download page

* Minus value of BPloci means that the break pointn is located before the CDS.

- In-frame and retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

Tgene

DOCK1

chr6:33280993

chr10:128768965

ENST00000280333

1207_1617

1866.0

Domain

DOCKER

Tgene

DOCK1

chr6:33280993

chr10:128768965

ENST00000280333

425_609

1866.0

Domain

C2 DOCK-type

Tgene

DOCK1

chr6:33280993

chr10:128768965

ENST00000280333

1687_1695

1866.0

Region

Phosphoinositide-binding

- In-frame and not-retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

Hgene

TAPBP

chr6:33280993

chr10:128768965

ENST00000374572

292_399

449.0

Domain

Note=Ig-like C1-type

Hgene

TAPBP

chr6:33280993

chr10:128768965

ENST00000383066

292_399

449.0

Domain

Note=Ig-like C1-type

Hgene

TAPBP

chr6:33280993

chr10:128768965

ENST00000383197

292_399

505.0

Domain

Note=Ig-like C1-type

Hgene

TAPBP

chr6:33280993

chr10:128768965

ENST00000383198

292_399

449.0

Domain

Note=Ig-like C1-type

Hgene

TAPBP

chr6:33280993

chr10:128768965

ENST00000395114

292_399

505.0

Domain

Note=Ig-like C1-type

Hgene

TAPBP

chr6:33280993

chr10:128768965

ENST00000417059

292_399

449.0

Domain

Note=Ig-like C1-type

Hgene

TAPBP

chr6:33280993

chr10:128768965

ENST00000434618

292_399

156

449.0

Domain

Note=Ig-like C1-type

Hgene

TAPBP

chr6:33280993

chr10:128768965

ENST00000456807

292_399

505.0

Domain

Note=Ig-like C1-type

Hgene

TAPBP

chr6:33280993

chr10:128768965

ENST00000374572

21_414

449.0

Topological domain

Lumenal

Hgene

TAPBP

chr6:33280993

chr10:128768965

ENST00000374572

436_448

449.0

Topological domain

Cytoplasmic

Hgene

TAPBP

chr6:33280993

chr10:128768965

ENST00000383066

21_414

449.0

Topological domain

Lumenal

Hgene

TAPBP

chr6:33280993

chr10:128768965

ENST00000383066

436_448

449.0

Topological domain

Cytoplasmic

Hgene

TAPBP

chr6:33280993

chr10:128768965

ENST00000383197

21_414

505.0

Topological domain

Lumenal

Hgene

TAPBP

chr6:33280993

chr10:128768965

ENST00000383197

436_448

505.0

Topological domain

Cytoplasmic

Hgene

TAPBP

chr6:33280993

chr10:128768965

ENST00000383198

21_414

449.0

Topological domain

Lumenal

Hgene

TAPBP

chr6:33280993

chr10:128768965

ENST00000383198

436_448

449.0

Topological domain

Cytoplasmic

Hgene

TAPBP

chr6:33280993

chr10:128768965

ENST00000395114

21_414

505.0

Topological domain

Lumenal

Hgene

TAPBP

chr6:33280993

chr10:128768965

ENST00000395114

436_448

505.0

Topological domain

Cytoplasmic

Hgene

TAPBP

chr6:33280993

chr10:128768965

ENST00000417059

21_414

449.0

Topological domain

Lumenal

Hgene

TAPBP

chr6:33280993

chr10:128768965

ENST00000417059

436_448

449.0

Topological domain

Cytoplasmic

Hgene

TAPBP

chr6:33280993

chr10:128768965

ENST00000434618

21_414

156

449.0

Topological domain

Lumenal

Hgene

TAPBP

chr6:33280993

chr10:128768965

ENST00000434618

436_448

156

449.0

Topological domain

Cytoplasmic

Hgene

TAPBP

chr6:33280993

chr10:128768965

ENST00000456807

21_414

505.0

Topological domain

Lumenal

Hgene

TAPBP

chr6:33280993

chr10:128768965

ENST00000456807

436_448

505.0

Topological domain

Cytoplasmic

Hgene

TAPBP

chr6:33280993

chr10:128768965

ENST00000374572

415_435

449.0

Transmembrane

Helical

Hgene

TAPBP

chr6:33280993

chr10:128768965

ENST00000383066

415_435

449.0

Transmembrane

Helical

Hgene

TAPBP

chr6:33280993

chr10:128768965

ENST00000383197

415_435

505.0

Transmembrane

Helical

Hgene

TAPBP

chr6:33280993

chr10:128768965

ENST00000383198

415_435

449.0

Transmembrane

Helical

Hgene

TAPBP

chr6:33280993

chr10:128768965

ENST00000395114

415_435

505.0

Transmembrane

Helical

Hgene

TAPBP

chr6:33280993

chr10:128768965

ENST00000417059

415_435

449.0

Transmembrane

Helical

Hgene

TAPBP

chr6:33280993

chr10:128768965

ENST00000434618

415_435

156

449.0

Transmembrane

Helical

Hgene

TAPBP

chr6:33280993

chr10:128768965

ENST00000456807

415_435

505.0

Transmembrane

Helical

Tgene

DOCK1

chr6:33280993

chr10:128768965

ENST00000280333

9_70

1866.0

Domain

SH3

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Fusion Gene Sequence for TAPBP-DOCK1

For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.

>89072_89072_1_TAPBP-DOCK1_TAPBP_chr6_33280993_ENST00000426633_DOCK1_chr10_128768965_ENST00000280333_length(transcript)=7282nt_BP=640nt
CTGGAGAGGATCTACCCGGGTCCCTGCCTGGCCAGTGGGGAAACACCGGTCCCCCAGGCACCTTCACCTAACCAGAGCGGGGATTTCCAC
CGCCCCTCATGCCGCCCTTTGGAGGAAAGTGAAAGTGAAAGGAGGAAGAGGAGGCTTCATGGCTGAGGAGGTCGCAGCGCCATGAAGTCC
CTGTCTCTGCTCCTCGCTGTGGCTTTGGGCCTGGCGACCGCCGTCTCAGCAGGACCCGCGGTGATCGAGTGTTGGTTCGTGGAGGATGCG
AGCGGAAAGGGCCTGGCCAAGAGACCCGGTGCACTGCTGTTGCGCCAGGGACCGGGGGAACCGCCGCCCCGGCCGGACCTCGACCCTGAG
CTCTATCTCAGTGTACACGACCCCGCGGGCGCCCTCCAGGCTGCCTTCAGGCGGTATCCCCGGGGCGCCCCCGCACCACACTGCGAGATG
AGCCGCTTCGTGCCTCTCCCCGCCTCTGCGAAATGGGCCAGCGGCCTGACCCCCGCGCAGAACTGCCCGCGGGCCCTGGATGGGGCTTGG
CTGATGGTCAGCATATCCAGCCCAGTCCTCAGCCTCTCCAGCCTCTTGCGACCACAGCCAGAGCCTCAGCAGGAGCCTGTTCTCATCACC
ATGGCAACAGCTTTTTATAACTATGATGCCAGAGGAGCGGATGAACTTTCTTTACAGATCGGAGACACTGTGCACATCTTAGAAACATAT
GAAGGGTGGTACCGAGGTTACACGTTACGAAAAAAGTCTAAGAAGGGTATATTTCCTGCTTCATATATTCATCTTAAAGAAGCGATAGTT
GAAGGAAAAGGGCAACATGAAACAGTCATCCCGGGTGACCTCCCCCTCATCCAGGAAGTCACCACGACACTCCGAGAGTGGTCCACCATC
TGGAGGCAGCTCTACGTGCAAGATAACAGGGAGATGTTTCGAAGTGTGCGGCACATGATCTATGACCTTATTGAATGGCGATCACAAATT
CTTTCTGGAACTCTGCCTCAGGATGAACTCAAAGAACTGAAGAAGAAGGTCACAGCCAAAATTGATTATGGAAACAGAATTCTAGATTTG
GACCTGGTGGTTAGAGATGAAGATGGGAATATTTTGGATCCAGAATTAACTAGCACGATTAGTCTCTTCAGAGCTCATGAAATAGCTTCT
AAACAAGTGGAGGAAAGGTTACAAGAGGAAAAATCTCAAAAGCAGAACATAGATATTAACAGACAAGCCAAGTTTGCTGCAACCCCTTCT
CTGGCCTTGTTTGTGAACCTCAAAAATGTGGTTTGTAAAATAGGAGAAGATGCTGAAGTCCTCATGTCTCTATATGACCCTGTGGAGTCC
AAATTCATCAGTGAGAACTACCTGGTTCGCTGGTCCAGTTCAGGATTACCTAAAGACATAGACAGATTACATAATTTGCGAGCCGTGTTT
ACTGACCTCGGAAGCAAAGACCTGAAAAGGGAGAAAATCAGTTTTGTCTGTCAGATTGTTCGCGTGGGTCGCATGGAGCTGAGGGACAAC
AACACCAGGAAACTGACCTCGGGGTTGCGGCGACCTTTTGGAGTGGCTGTGATGGATGTAACAGATATAATAAATGGAAAAGTAGATGAT
GAAGATAAGCAGCATTTCATTCCCTTTCAGCCGGTGGCAGGGGAGAATGACTTCCTTCAGACTGTTATAAACAAAGTCATCGCTGCCAAA
GAAGTCAACCACAAGGGGCAGGGTTTGTGGGTAACATTGAAATTACTTCCTGGAGATATCCATCAGATCCGAAAAGAGTTTCCGCATTTA
GTGGACAGGACCACAGCTGTGGCTCGAAAAACAGGGTTTCCGGAGATAATCATGCCTGGTGATGTTCGAAATGATATCTATGTAACATTA
GTTCAAGGAGATTTTGATAAAGGAAGCAAAACAACAGCGAAGAACGTGGAGGTCACGGTGTCTGTGTACGATGAGGATGGGAAACGATTA
GAGCATGTGATTTTCCCGGGTGCTGGTGATGAAGCGATTTCAGAGTACAAATCTGTGATTTACTACCAAGTAAAGCAGCCACGCTGGTTT
GAGACTGTTAAGGTGGCCATTCCCATCGAGGACGTTAACCGCAGTCACCTTCGGTTTACCTTCCGCCACAGGTCATCACAGGACTCTAAG
GATAAATCTGAGAAAATATTTGCACTAGCATTTGTCAAGCTGATGAGATACGATGGTACCACCCTGCGAGACGGAGAGCACGATCTTATC
GTCTATAAGGCCGAAGCAAAGAAGCTGGAAGATGCTGCCACGTACTTGAGTCTGCCCTCCACGAAGGCAGAGTTGGAAGAAAAGGGCCAC
TCGGCCACCGGCAAGAGCATGCAGAGCCTTGGGAGCTGCACCATTAGCAAGGACTCCTTCCAGATCTCCACGCTCGTGTGCTCCACCAAA
CTGACTCAGAACGTGGACCTTCTGGGGCTCTTGAAATGGCGCTCCAACACCAGCCTGCTGCAGCAGAACTTGAGGCAGCTGATGAAAGTC
GATGGTGGTGAAGTAGTGAAGTTTCTTCAGGACACGTTGGATGCCCTCTTCAACATCATGATGGAGAACTCAGAGAGTGAGACTTTTGAC
ACGTTAGTCTTTGATGCTCTGGTATTTATCATTGGACTGATTGCTGATAGAAAATTTCAGCATTTTAATCCTGTTTTGGAAACTTACATT
AAGAAACACTTTAGTGCAACGTTAGCCTACACGAAGTTGACAAAAGTGTTGAAGAACTACGTGGACGGTGCTGAGAAGCCGGGAGTAAAT
GAGCAGCTGTACAAAGCCATGAAAGCGCTAGAATCCATCTTCAAGTTCATCGTGCGCTCCAGGATCCTGTTCAATCAACTGTATGAAAAC
AAGGGAGAGGCTGACTTCGTGGAATCTTTGCTGCAGCTCTTCAGGTCCATCAATGACATGATGAGCAGCATGTCAGACCAGACCGTCCGG
GTGAAGGGGGCAGCACTGAAATACTTACCAACGATCGTCAACGATGTGAAATTGGTGTTTGATCCCAAAGAGCTCAGCAAAATGTTTACT
GAATTCATCCTCAATGTTCCCATGGGCTTGCTGACCATCCAGAAACTCTACTGCTTGATCGAAATCGTCCACAGTGACCTCTTCACACAG
CATGACTGCAGAGAGATCCTGCTTCCCATGATGACCGATCAGCTCAAGTACCATCTGGAGAGACAGGAGGACCTGGAGGCCTGCTGTCAG
CTGCTCAGCCACATCCTGGAGGTGCTGTACAGGAAGGACGTGGGGCCAACCCAGAGGCACGTCCAGATTATCATGGAGAAACTTCTCCGG
ACCGTGAACCGAACCGTCATTTCCATGGGACGAGATTCTGAACTCATTGGAAACTTCGTGGCTTGCATGACAGCTATTTTACGACAAATG
GAAGATTACCATTATGCCCACTTGATCAAGACTTTTGGGAAAATGAGGACTGATGTGGTAGATTTCCTAATGGAAACATTCATCATGTTT
AAGAACCTCATTGGAAAGAACGTTTACCCCTTCGACTGGGTGATCATGAACATGGTGCAAAATAAAGTCTTCCTGCGAGCAATTAATCAG
TATGCAGATATGCTGAACAAAAAATTTCTGGATCAAGCCAACTTTGAGCTACAGCTGTGGAACAACTACTTTCACCTGGCTGTTGCTTTC
CTTACTCAAGAGTCCCTGCAACTGGAGAATTTTTCAAGTGCCAAGAGAGCCAAAATCCTTAACAAGTACGGAGATATGAGGAGACAGATT
GGCTTTGAAATCAGAGACATGTGGTACAACCTTGGTCAACACAAGATAAAGTTCATTCCAGAAATGGTGGGCCCAATATTAGAAATGACA
TTAATTCCCGAGACGGAGCTGCGCAAAGCCACCATCCCCATCTTCTTTGATATGATGCAGTGTGAATTCCATTCGACCCGAAGCTTCCAA
ATGTTTGAAAATGAGATCATCACCAAGCTGGATCATGAAGTCGAAGGAGGCAGAGGAGACGAACAGTACAAAGTGTTATTTGATAAAATC
CTTCTGGAACACTGCAGGAAGCACAAATACCTCGCCAAAACAGGAGAAACTTTTGTAAAACTCGTTGTGCGCTTAATGGAAAGGCTTTTG
GATTATAGAACCATCATGCACGACGAGAACAAAGAAAACCGCATGAGCTGCACCGTCAATGTGCTGAATTTCTACAAAGAAATTGAAAGA
GAAGAAATGTATATAAGGTATTTGTACAAGCTCTGTGACCTGCACAAGGAGTGTGATAACTACACCGAAGCGGCTTACACCTTGCTTCTC
CATGCAAAGCTTCTTAAGTGGTCGGAGGATGTGTGTGTGGCCCACCTCACCCAGCGGGACGGGTACCAGGCCACCACGCAGGGACAGCTG
AAGGAGCAGCTCTACCAGGAAATCATCCACTACTTCGACAAAGGCAAGATGTGGGAGGAGGCCATTGCCTTGGGCAAGGAGCTAGCCGAG
CAGTATGAGAACGAAATGTTTGATTATGAGCAACTCAGCGAATTGCTGAAAAAACAGGCTCAGTTTTATGAAAACATCGTCAAAGTGATC
AGGCCCAAGCCTGACTATTTTGCTGTTGGCTACTACGGACAAGGGTTCCCCACATTCCTGCGGGGAAAAGTTTTCATTTACCGAGGGAAA
GAGTATGAGCGCCGGGAAGATTTTGAGGCTCGGCTCTTAACTCAGTTTCCAAACGCCGAGAAAATGAAGACAACATCTCCACCAGGCGAC
GATATTAAAAACTCTCCTGGCCAGTATATTCAGTGCTTCACAGTGAAGCCCAAACTCGATCTGCCTCCTAAGTTTCACAGGCCAGTGTCA
GAGCAGATTGTAAGTTTTTACAGGGTGAACGAGGTCCAGCGATTTGAATATTCTCGGCCAATCCGGAAGGGAGAGAAAAACCCAGACAAT
GAATTTGCGAATATGTGGATCGAGAGAACCATATATACAACTGCATATAAATTACCTGGAATTTTAAGGTGGTTTGAGGTCAAGTCTGTT
TTCATGGTGGAAATCAGCCCCCTGGAGAATGCCATTGAGACCATGCAGCTGACGAACGACAAGATCAACAGCATGGTGCAGCAGCACCTG
GATGACCCCAGCCTGCCCATCAACCCGCTCTCCATGCTCCTGAACGGCATCGTGGACCCAGCTGTCATGGGGGGCTTCGCAAACTACGAA
AAGGCCTTCTTTACAGACCGGTACCTGCAGGAGCACCCTGAGGCCCATGAAAAGATCGAGAAGCTCAAGGACCTGATTGCTTGGCAGATT
CCTTTTCTGGCCGAAGGGATCAGAATCCATGGAGACAAAGTCACGGAGGCACTGAGGCCGTTCCACGAGAGGATGGAGGCCTGTTTCAAA
CAGCTGAAGGAAAAGGTGGAGAAAGAGTACGGCGTCCGAATCATGCCCTCAAGTCTGGATGATAGAAGAGGCAGCCGCCCCCGGTCCATG
GTGCGGTCCTTCACGATGCCTTCCTCATCCCGCCCTCTGTCTGTGGCCTCTGTCTCTTCCCTCTCATCGGACAGCACCCCTTCCAGACCA
GGCTCCGACGGGTTTGCCCTGGAGCCTCTCCTGCCAAAGAAAATGCACTCCAGGTCCCAGGACAAGCTGGACAAGGATGACCTGGAGAAG
GAGAAGAAGGACAAGAAGAAGGAAAAAAGGAACAGCAAACATCAAGAGATATTTGAGAAAGAATTTAAACCCACCGACATTTCCCTGCAG
CAGTCTGAGGCTGTGATCCTTTCGGAAACGATAAGTCCCCTGCGGCCCCAGAGACCGAAGAGCCAGGTGATGAACGTCATTGGAAGCGAA
AGGCGCTTCTCGGTGTCCCCCTCGTCACCGTCCTCCCAGCAAACACCCCCTCCAGTTACACCAAGGGCCAAGCTCAGCTTCAGCATGCAG
TCGAGCTTGGAGCTGAACGGCATGACGGGGGCGGACGTGGCCGATGTCCCACCCCCTCTGCCTCTCAAAGGCAGCGTGGCAGATTACGGG
AATTTGATGGAAAACCAGGACTTGCTGGGCTCGCCAACACCTCCACCTCCCCCTCCACACCAGAGGCATCTGCCACCTCCACTGCCCAGC
AAAACTCCGCCTCCTCCCCCTCCAAAGACAACTCGCAAGCAGGCATCGGTGGACTCCGGGATCGTGCAGTGACGTCGCAAGCCTCTCTGG
AAAGAGTGTGCTGCCCCTCCCCATCTCCATGCCCTCTCCTTCTGTGTCCCCTGAGTCTGCTGTTTACCTCATTGGGCCTGTGATGTTAAC
ATTTCGTGCGACTGCTTTTTCTTCAAAGGAGTTCAGTTCTCACCATGGAGTGAGTGGCCTTTAGCGTCATGGAGCAAGGTGGGTCTGGGA
GGTAGATATGGGTCCGGGATGTGCTATCGTAGTTATCAGAGTTGGGGGCCTCTGAGTGTGTCTGGCTCTGAGAGAGTCTGAGTCTTGCCC
AAACATTCTTTCTTTTTGTGCCAAATGACTTGCATTTGCAAAGAGCTCAATTGCTCTGAGCTCAGCCAAGTAGGAGAGGCTAGGCCATCA
CTCTTAGGAAGCTGTGTAGTGATGATGTATAAGAATCCTCCTCACTGTCATGGGATGTTGTATCCAGCCCCTCCTTGTTCCAGCCGGTGG
TGTGACTTCGTTGGTTGAGGTGTGTCTCCAACCTACATCAGACCATGAAGTTCAACCCCTCCAGGGAAGCTCCTGATTTCCCCTGCATAA
TTGAAAATAGGATATTTCTCAGCTATTGAACAGTTACTAATTTATGGGGTGGAAACAGCATTAAGAATACTGAATCAAATGGAAAAACAA
ATGAATACAGGAAGATAAGTGTTCGTTCTTTTCTGAAAAAGAGTATGTGTACCACAAGAGCTGGTTTTAATTGGGTGAATTGTTTTTGTC
CTCATTCTGTACAGAAATTTGTATATATGATGGTTCTTAGAACTTGTTTTAATTTTTGTGGTCCTTCCGTTTATTATAATAGGCGTCCAC
CAATGATTATCCATATGTGTTCTTAATTTTTAACTGCTGGAAGTGTTAAAACACACACACACACACACACACATTTTTTTTTTGAGAACT
CCAAAGTCCTGAAAATTTTGGTGGACAATGATTTTTAAAAAACTAACTTTGTATAACCTAATATTTGTATTCTCTCATCTATATTTTTTT

>89072_89072_1_TAPBP-DOCK1_TAPBP_chr6_33280993_ENST00000426633_DOCK1_chr10_128768965_ENST00000280333_length(amino acids)=2006AA_BP=155
MKSLSLLLAVALGLATAVSAGPAVIECWFVEDASGKGLAKRPGALLLRQGPGEPPPRPDLDPELYLSVHDPAGALQAAFRRYPRGAPAPH
CEMSRFVPLPASAKWASGLTPAQNCPRALDGAWLMVSISSPVLSLSSLLRPQPEPQQEPVLITMATAFYNYDARGADELSLQIGDTVHIL
ETYEGWYRGYTLRKKSKKGIFPASYIHLKEAIVEGKGQHETVIPGDLPLIQEVTTTLREWSTIWRQLYVQDNREMFRSVRHMIYDLIEWR
SQILSGTLPQDELKELKKKVTAKIDYGNRILDLDLVVRDEDGNILDPELTSTISLFRAHEIASKQVEERLQEEKSQKQNIDINRQAKFAA
TPSLALFVNLKNVVCKIGEDAEVLMSLYDPVESKFISENYLVRWSSSGLPKDIDRLHNLRAVFTDLGSKDLKREKISFVCQIVRVGRMEL
RDNNTRKLTSGLRRPFGVAVMDVTDIINGKVDDEDKQHFIPFQPVAGENDFLQTVINKVIAAKEVNHKGQGLWVTLKLLPGDIHQIRKEF
PHLVDRTTAVARKTGFPEIIMPGDVRNDIYVTLVQGDFDKGSKTTAKNVEVTVSVYDEDGKRLEHVIFPGAGDEAISEYKSVIYYQVKQP
RWFETVKVAIPIEDVNRSHLRFTFRHRSSQDSKDKSEKIFALAFVKLMRYDGTTLRDGEHDLIVYKAEAKKLEDAATYLSLPSTKAELEE
KGHSATGKSMQSLGSCTISKDSFQISTLVCSTKLTQNVDLLGLLKWRSNTSLLQQNLRQLMKVDGGEVVKFLQDTLDALFNIMMENSESE
TFDTLVFDALVFIIGLIADRKFQHFNPVLETYIKKHFSATLAYTKLTKVLKNYVDGAEKPGVNEQLYKAMKALESIFKFIVRSRILFNQL
YENKGEADFVESLLQLFRSINDMMSSMSDQTVRVKGAALKYLPTIVNDVKLVFDPKELSKMFTEFILNVPMGLLTIQKLYCLIEIVHSDL
FTQHDCREILLPMMTDQLKYHLERQEDLEACCQLLSHILEVLYRKDVGPTQRHVQIIMEKLLRTVNRTVISMGRDSELIGNFVACMTAIL
RQMEDYHYAHLIKTFGKMRTDVVDFLMETFIMFKNLIGKNVYPFDWVIMNMVQNKVFLRAINQYADMLNKKFLDQANFELQLWNNYFHLA
VAFLTQESLQLENFSSAKRAKILNKYGDMRRQIGFEIRDMWYNLGQHKIKFIPEMVGPILEMTLIPETELRKATIPIFFDMMQCEFHSTR
SFQMFENEIITKLDHEVEGGRGDEQYKVLFDKILLEHCRKHKYLAKTGETFVKLVVRLMERLLDYRTIMHDENKENRMSCTVNVLNFYKE
IEREEMYIRYLYKLCDLHKECDNYTEAAYTLLLHAKLLKWSEDVCVAHLTQRDGYQATTQGQLKEQLYQEIIHYFDKGKMWEEAIALGKE
LAEQYENEMFDYEQLSELLKKQAQFYENIVKVIRPKPDYFAVGYYGQGFPTFLRGKVFIYRGKEYERREDFEARLLTQFPNAEKMKTTSP
PGDDIKNSPGQYIQCFTVKPKLDLPPKFHRPVSEQIVSFYRVNEVQRFEYSRPIRKGEKNPDNEFANMWIERTIYTTAYKLPGILRWFEV
KSVFMVEISPLENAIETMQLTNDKINSMVQQHLDDPSLPINPLSMLLNGIVDPAVMGGFANYEKAFFTDRYLQEHPEAHEKIEKLKDLIA
WQIPFLAEGIRIHGDKVTEALRPFHERMEACFKQLKEKVEKEYGVRIMPSSLDDRRGSRPRSMVRSFTMPSSSRPLSVASVSSLSSDSTP
SRPGSDGFALEPLLPKKMHSRSQDKLDKDDLEKEKKDKKKEKRNSKHQEIFEKEFKPTDISLQQSEAVILSETISPLRPQRPKSQVMNVI
GSERRFSVSPSSPSSQQTPPPVTPRAKLSFSMQSSLELNGMTGADVADVPPPLPLKGSVADYGNLMENQDLLGSPTPPPPPPHQRHLPPP

--------------------------------------------------------------
>89072_89072_2_TAPBP-DOCK1_TAPBP_chr6_33280993_ENST00000434618_DOCK1_chr10_128768965_ENST00000280333_length(transcript)=7457nt_BP=815nt
GGGGACGCGGCACAGATAGGGGGAAGCCGGAGTAATGGTTTTCGGGCAAGTGGATGTTGGAGAGCACACACAGGAGTTGGGGGGCGGGGG
AGGGCCTGGGGTTGGGGAGGGCTCGAACTCGGGGCTGCTGGGTAGTCCAGGAGGGCGCGGTAAGGCTGGGGTGTCCTGGTGAGAACTGGA
GAGGATCTACCCGGGTCCCTGCCTGGCCAGTGGGGAAACACCGGTCCCCCAGGCACCTTCACCTAACCAGAGCGGGGATTTCCACCGCCC
CTCATGCCGCCCTTTGGAGGAAAGTGAAAGTGAAAGGAGGAAGAGGAGGCTTCATGGCTGAGGAGGTCGCAGCGCCATGAAGTCCCTGTC
TCTGCTCCTCGCTGTGGCTTTGGGCCTGGCGACCGCCGTCTCAGCAGGACCCGCGGTGATCGAGTGTTGGTTCGTGGAGGATGCGAGCGG
AAAGGGCCTGGCCAAGAGACCCGGTGCACTGCTGTTGCGCCAGGGACCGGGGGAACCGCCGCCCCGGCCGGACCTCGACCCTGAGCTCTA
TCTCAGTGTACACGACCCCGCGGGCGCCCTCCAGGCTGCCTTCAGGCGGTATCCCCGGGGCGCCCCCGCACCACACTGCGAGATGAGCCG
CTTCGTGCCTCTCCCCGCCTCTGCGAAATGGGCCAGCGGCCTGACCCCCGCGCAGAACTGCCCGCGGGCCCTGGATGGGGCTTGGCTGAT
GGTCAGCATATCCAGCCCAGTCCTCAGCCTCTCCAGCCTCTTGCGACCACAGCCAGAGCCTCAGCAGGAGCCTGTTCTCATCACCATGGC
AACAGCTTTTTATAACTATGATGCCAGAGGAGCGGATGAACTTTCTTTACAGATCGGAGACACTGTGCACATCTTAGAAACATATGAAGG
GTGGTACCGAGGTTACACGTTACGAAAAAAGTCTAAGAAGGGTATATTTCCTGCTTCATATATTCATCTTAAAGAAGCGATAGTTGAAGG
AAAAGGGCAACATGAAACAGTCATCCCGGGTGACCTCCCCCTCATCCAGGAAGTCACCACGACACTCCGAGAGTGGTCCACCATCTGGAG
GCAGCTCTACGTGCAAGATAACAGGGAGATGTTTCGAAGTGTGCGGCACATGATCTATGACCTTATTGAATGGCGATCACAAATTCTTTC
TGGAACTCTGCCTCAGGATGAACTCAAAGAACTGAAGAAGAAGGTCACAGCCAAAATTGATTATGGAAACAGAATTCTAGATTTGGACCT
GGTGGTTAGAGATGAAGATGGGAATATTTTGGATCCAGAATTAACTAGCACGATTAGTCTCTTCAGAGCTCATGAAATAGCTTCTAAACA
AGTGGAGGAAAGGTTACAAGAGGAAAAATCTCAAAAGCAGAACATAGATATTAACAGACAAGCCAAGTTTGCTGCAACCCCTTCTCTGGC
CTTGTTTGTGAACCTCAAAAATGTGGTTTGTAAAATAGGAGAAGATGCTGAAGTCCTCATGTCTCTATATGACCCTGTGGAGTCCAAATT
CATCAGTGAGAACTACCTGGTTCGCTGGTCCAGTTCAGGATTACCTAAAGACATAGACAGATTACATAATTTGCGAGCCGTGTTTACTGA
CCTCGGAAGCAAAGACCTGAAAAGGGAGAAAATCAGTTTTGTCTGTCAGATTGTTCGCGTGGGTCGCATGGAGCTGAGGGACAACAACAC
CAGGAAACTGACCTCGGGGTTGCGGCGACCTTTTGGAGTGGCTGTGATGGATGTAACAGATATAATAAATGGAAAAGTAGATGATGAAGA
TAAGCAGCATTTCATTCCCTTTCAGCCGGTGGCAGGGGAGAATGACTTCCTTCAGACTGTTATAAACAAAGTCATCGCTGCCAAAGAAGT
CAACCACAAGGGGCAGGGTTTGTGGGTAACATTGAAATTACTTCCTGGAGATATCCATCAGATCCGAAAAGAGTTTCCGCATTTAGTGGA
CAGGACCACAGCTGTGGCTCGAAAAACAGGGTTTCCGGAGATAATCATGCCTGGTGATGTTCGAAATGATATCTATGTAACATTAGTTCA
AGGAGATTTTGATAAAGGAAGCAAAACAACAGCGAAGAACGTGGAGGTCACGGTGTCTGTGTACGATGAGGATGGGAAACGATTAGAGCA
TGTGATTTTCCCGGGTGCTGGTGATGAAGCGATTTCAGAGTACAAATCTGTGATTTACTACCAAGTAAAGCAGCCACGCTGGTTTGAGAC
TGTTAAGGTGGCCATTCCCATCGAGGACGTTAACCGCAGTCACCTTCGGTTTACCTTCCGCCACAGGTCATCACAGGACTCTAAGGATAA
ATCTGAGAAAATATTTGCACTAGCATTTGTCAAGCTGATGAGATACGATGGTACCACCCTGCGAGACGGAGAGCACGATCTTATCGTCTA
TAAGGCCGAAGCAAAGAAGCTGGAAGATGCTGCCACGTACTTGAGTCTGCCCTCCACGAAGGCAGAGTTGGAAGAAAAGGGCCACTCGGC
CACCGGCAAGAGCATGCAGAGCCTTGGGAGCTGCACCATTAGCAAGGACTCCTTCCAGATCTCCACGCTCGTGTGCTCCACCAAACTGAC
TCAGAACGTGGACCTTCTGGGGCTCTTGAAATGGCGCTCCAACACCAGCCTGCTGCAGCAGAACTTGAGGCAGCTGATGAAAGTCGATGG
TGGTGAAGTAGTGAAGTTTCTTCAGGACACGTTGGATGCCCTCTTCAACATCATGATGGAGAACTCAGAGAGTGAGACTTTTGACACGTT
AGTCTTTGATGCTCTGGTATTTATCATTGGACTGATTGCTGATAGAAAATTTCAGCATTTTAATCCTGTTTTGGAAACTTACATTAAGAA
ACACTTTAGTGCAACGTTAGCCTACACGAAGTTGACAAAAGTGTTGAAGAACTACGTGGACGGTGCTGAGAAGCCGGGAGTAAATGAGCA
GCTGTACAAAGCCATGAAAGCGCTAGAATCCATCTTCAAGTTCATCGTGCGCTCCAGGATCCTGTTCAATCAACTGTATGAAAACAAGGG
AGAGGCTGACTTCGTGGAATCTTTGCTGCAGCTCTTCAGGTCCATCAATGACATGATGAGCAGCATGTCAGACCAGACCGTCCGGGTGAA
GGGGGCAGCACTGAAATACTTACCAACGATCGTCAACGATGTGAAATTGGTGTTTGATCCCAAAGAGCTCAGCAAAATGTTTACTGAATT
CATCCTCAATGTTCCCATGGGCTTGCTGACCATCCAGAAACTCTACTGCTTGATCGAAATCGTCCACAGTGACCTCTTCACACAGCATGA
CTGCAGAGAGATCCTGCTTCCCATGATGACCGATCAGCTCAAGTACCATCTGGAGAGACAGGAGGACCTGGAGGCCTGCTGTCAGCTGCT
CAGCCACATCCTGGAGGTGCTGTACAGGAAGGACGTGGGGCCAACCCAGAGGCACGTCCAGATTATCATGGAGAAACTTCTCCGGACCGT
GAACCGAACCGTCATTTCCATGGGACGAGATTCTGAACTCATTGGAAACTTCGTGGCTTGCATGACAGCTATTTTACGACAAATGGAAGA
TTACCATTATGCCCACTTGATCAAGACTTTTGGGAAAATGAGGACTGATGTGGTAGATTTCCTAATGGAAACATTCATCATGTTTAAGAA
CCTCATTGGAAAGAACGTTTACCCCTTCGACTGGGTGATCATGAACATGGTGCAAAATAAAGTCTTCCTGCGAGCAATTAATCAGTATGC
AGATATGCTGAACAAAAAATTTCTGGATCAAGCCAACTTTGAGCTACAGCTGTGGAACAACTACTTTCACCTGGCTGTTGCTTTCCTTAC
TCAAGAGTCCCTGCAACTGGAGAATTTTTCAAGTGCCAAGAGAGCCAAAATCCTTAACAAGTACGGAGATATGAGGAGACAGATTGGCTT
TGAAATCAGAGACATGTGGTACAACCTTGGTCAACACAAGATAAAGTTCATTCCAGAAATGGTGGGCCCAATATTAGAAATGACATTAAT
TCCCGAGACGGAGCTGCGCAAAGCCACCATCCCCATCTTCTTTGATATGATGCAGTGTGAATTCCATTCGACCCGAAGCTTCCAAATGTT
TGAAAATGAGATCATCACCAAGCTGGATCATGAAGTCGAAGGAGGCAGAGGAGACGAACAGTACAAAGTGTTATTTGATAAAATCCTTCT
GGAACACTGCAGGAAGCACAAATACCTCGCCAAAACAGGAGAAACTTTTGTAAAACTCGTTGTGCGCTTAATGGAAAGGCTTTTGGATTA
TAGAACCATCATGCACGACGAGAACAAAGAAAACCGCATGAGCTGCACCGTCAATGTGCTGAATTTCTACAAAGAAATTGAAAGAGAAGA
AATGTATATAAGGTATTTGTACAAGCTCTGTGACCTGCACAAGGAGTGTGATAACTACACCGAAGCGGCTTACACCTTGCTTCTCCATGC
AAAGCTTCTTAAGTGGTCGGAGGATGTGTGTGTGGCCCACCTCACCCAGCGGGACGGGTACCAGGCCACCACGCAGGGACAGCTGAAGGA
GCAGCTCTACCAGGAAATCATCCACTACTTCGACAAAGGCAAGATGTGGGAGGAGGCCATTGCCTTGGGCAAGGAGCTAGCCGAGCAGTA
TGAGAACGAAATGTTTGATTATGAGCAACTCAGCGAATTGCTGAAAAAACAGGCTCAGTTTTATGAAAACATCGTCAAAGTGATCAGGCC
CAAGCCTGACTATTTTGCTGTTGGCTACTACGGACAAGGGTTCCCCACATTCCTGCGGGGAAAAGTTTTCATTTACCGAGGGAAAGAGTA
TGAGCGCCGGGAAGATTTTGAGGCTCGGCTCTTAACTCAGTTTCCAAACGCCGAGAAAATGAAGACAACATCTCCACCAGGCGACGATAT
TAAAAACTCTCCTGGCCAGTATATTCAGTGCTTCACAGTGAAGCCCAAACTCGATCTGCCTCCTAAGTTTCACAGGCCAGTGTCAGAGCA
GATTGTAAGTTTTTACAGGGTGAACGAGGTCCAGCGATTTGAATATTCTCGGCCAATCCGGAAGGGAGAGAAAAACCCAGACAATGAATT
TGCGAATATGTGGATCGAGAGAACCATATATACAACTGCATATAAATTACCTGGAATTTTAAGGTGGTTTGAGGTCAAGTCTGTTTTCAT
GGTGGAAATCAGCCCCCTGGAGAATGCCATTGAGACCATGCAGCTGACGAACGACAAGATCAACAGCATGGTGCAGCAGCACCTGGATGA
CCCCAGCCTGCCCATCAACCCGCTCTCCATGCTCCTGAACGGCATCGTGGACCCAGCTGTCATGGGGGGCTTCGCAAACTACGAAAAGGC
CTTCTTTACAGACCGGTACCTGCAGGAGCACCCTGAGGCCCATGAAAAGATCGAGAAGCTCAAGGACCTGATTGCTTGGCAGATTCCTTT
TCTGGCCGAAGGGATCAGAATCCATGGAGACAAAGTCACGGAGGCACTGAGGCCGTTCCACGAGAGGATGGAGGCCTGTTTCAAACAGCT
GAAGGAAAAGGTGGAGAAAGAGTACGGCGTCCGAATCATGCCCTCAAGTCTGGATGATAGAAGAGGCAGCCGCCCCCGGTCCATGGTGCG
GTCCTTCACGATGCCTTCCTCATCCCGCCCTCTGTCTGTGGCCTCTGTCTCTTCCCTCTCATCGGACAGCACCCCTTCCAGACCAGGCTC
CGACGGGTTTGCCCTGGAGCCTCTCCTGCCAAAGAAAATGCACTCCAGGTCCCAGGACAAGCTGGACAAGGATGACCTGGAGAAGGAGAA
GAAGGACAAGAAGAAGGAAAAAAGGAACAGCAAACATCAAGAGATATTTGAGAAAGAATTTAAACCCACCGACATTTCCCTGCAGCAGTC
TGAGGCTGTGATCCTTTCGGAAACGATAAGTCCCCTGCGGCCCCAGAGACCGAAGAGCCAGGTGATGAACGTCATTGGAAGCGAAAGGCG
CTTCTCGGTGTCCCCCTCGTCACCGTCCTCCCAGCAAACACCCCCTCCAGTTACACCAAGGGCCAAGCTCAGCTTCAGCATGCAGTCGAG
CTTGGAGCTGAACGGCATGACGGGGGCGGACGTGGCCGATGTCCCACCCCCTCTGCCTCTCAAAGGCAGCGTGGCAGATTACGGGAATTT
GATGGAAAACCAGGACTTGCTGGGCTCGCCAACACCTCCACCTCCCCCTCCACACCAGAGGCATCTGCCACCTCCACTGCCCAGCAAAAC
TCCGCCTCCTCCCCCTCCAAAGACAACTCGCAAGCAGGCATCGGTGGACTCCGGGATCGTGCAGTGACGTCGCAAGCCTCTCTGGAAAGA
GTGTGCTGCCCCTCCCCATCTCCATGCCCTCTCCTTCTGTGTCCCCTGAGTCTGCTGTTTACCTCATTGGGCCTGTGATGTTAACATTTC
GTGCGACTGCTTTTTCTTCAAAGGAGTTCAGTTCTCACCATGGAGTGAGTGGCCTTTAGCGTCATGGAGCAAGGTGGGTCTGGGAGGTAG
ATATGGGTCCGGGATGTGCTATCGTAGTTATCAGAGTTGGGGGCCTCTGAGTGTGTCTGGCTCTGAGAGAGTCTGAGTCTTGCCCAAACA
TTCTTTCTTTTTGTGCCAAATGACTTGCATTTGCAAAGAGCTCAATTGCTCTGAGCTCAGCCAAGTAGGAGAGGCTAGGCCATCACTCTT
AGGAAGCTGTGTAGTGATGATGTATAAGAATCCTCCTCACTGTCATGGGATGTTGTATCCAGCCCCTCCTTGTTCCAGCCGGTGGTGTGA
CTTCGTTGGTTGAGGTGTGTCTCCAACCTACATCAGACCATGAAGTTCAACCCCTCCAGGGAAGCTCCTGATTTCCCCTGCATAATTGAA
AATAGGATATTTCTCAGCTATTGAACAGTTACTAATTTATGGGGTGGAAACAGCATTAAGAATACTGAATCAAATGGAAAAACAAATGAA
TACAGGAAGATAAGTGTTCGTTCTTTTCTGAAAAAGAGTATGTGTACCACAAGAGCTGGTTTTAATTGGGTGAATTGTTTTTGTCCTCAT
TCTGTACAGAAATTTGTATATATGATGGTTCTTAGAACTTGTTTTAATTTTTGTGGTCCTTCCGTTTATTATAATAGGCGTCCACCAATG
ATTATCCATATGTGTTCTTAATTTTTAACTGCTGGAAGTGTTAAAACACACACACACACACACACACATTTTTTTTTTGAGAACTCCAAA
GTCCTGAAAATTTTGGTGGACAATGATTTTTAAAAAACTAACTTTGTATAACCTAATATTTGTATTCTCTCATCTATATTTTTTTATTCA

>89072_89072_2_TAPBP-DOCK1_TAPBP_chr6_33280993_ENST00000434618_DOCK1_chr10_128768965_ENST00000280333_length(amino acids)=2006AA_BP=155
MKSLSLLLAVALGLATAVSAGPAVIECWFVEDASGKGLAKRPGALLLRQGPGEPPPRPDLDPELYLSVHDPAGALQAAFRRYPRGAPAPH
CEMSRFVPLPASAKWASGLTPAQNCPRALDGAWLMVSISSPVLSLSSLLRPQPEPQQEPVLITMATAFYNYDARGADELSLQIGDTVHIL
ETYEGWYRGYTLRKKSKKGIFPASYIHLKEAIVEGKGQHETVIPGDLPLIQEVTTTLREWSTIWRQLYVQDNREMFRSVRHMIYDLIEWR
SQILSGTLPQDELKELKKKVTAKIDYGNRILDLDLVVRDEDGNILDPELTSTISLFRAHEIASKQVEERLQEEKSQKQNIDINRQAKFAA
TPSLALFVNLKNVVCKIGEDAEVLMSLYDPVESKFISENYLVRWSSSGLPKDIDRLHNLRAVFTDLGSKDLKREKISFVCQIVRVGRMEL
RDNNTRKLTSGLRRPFGVAVMDVTDIINGKVDDEDKQHFIPFQPVAGENDFLQTVINKVIAAKEVNHKGQGLWVTLKLLPGDIHQIRKEF
PHLVDRTTAVARKTGFPEIIMPGDVRNDIYVTLVQGDFDKGSKTTAKNVEVTVSVYDEDGKRLEHVIFPGAGDEAISEYKSVIYYQVKQP
RWFETVKVAIPIEDVNRSHLRFTFRHRSSQDSKDKSEKIFALAFVKLMRYDGTTLRDGEHDLIVYKAEAKKLEDAATYLSLPSTKAELEE
KGHSATGKSMQSLGSCTISKDSFQISTLVCSTKLTQNVDLLGLLKWRSNTSLLQQNLRQLMKVDGGEVVKFLQDTLDALFNIMMENSESE
TFDTLVFDALVFIIGLIADRKFQHFNPVLETYIKKHFSATLAYTKLTKVLKNYVDGAEKPGVNEQLYKAMKALESIFKFIVRSRILFNQL
YENKGEADFVESLLQLFRSINDMMSSMSDQTVRVKGAALKYLPTIVNDVKLVFDPKELSKMFTEFILNVPMGLLTIQKLYCLIEIVHSDL
FTQHDCREILLPMMTDQLKYHLERQEDLEACCQLLSHILEVLYRKDVGPTQRHVQIIMEKLLRTVNRTVISMGRDSELIGNFVACMTAIL
RQMEDYHYAHLIKTFGKMRTDVVDFLMETFIMFKNLIGKNVYPFDWVIMNMVQNKVFLRAINQYADMLNKKFLDQANFELQLWNNYFHLA
VAFLTQESLQLENFSSAKRAKILNKYGDMRRQIGFEIRDMWYNLGQHKIKFIPEMVGPILEMTLIPETELRKATIPIFFDMMQCEFHSTR
SFQMFENEIITKLDHEVEGGRGDEQYKVLFDKILLEHCRKHKYLAKTGETFVKLVVRLMERLLDYRTIMHDENKENRMSCTVNVLNFYKE
IEREEMYIRYLYKLCDLHKECDNYTEAAYTLLLHAKLLKWSEDVCVAHLTQRDGYQATTQGQLKEQLYQEIIHYFDKGKMWEEAIALGKE
LAEQYENEMFDYEQLSELLKKQAQFYENIVKVIRPKPDYFAVGYYGQGFPTFLRGKVFIYRGKEYERREDFEARLLTQFPNAEKMKTTSP
PGDDIKNSPGQYIQCFTVKPKLDLPPKFHRPVSEQIVSFYRVNEVQRFEYSRPIRKGEKNPDNEFANMWIERTIYTTAYKLPGILRWFEV
KSVFMVEISPLENAIETMQLTNDKINSMVQQHLDDPSLPINPLSMLLNGIVDPAVMGGFANYEKAFFTDRYLQEHPEAHEKIEKLKDLIA
WQIPFLAEGIRIHGDKVTEALRPFHERMEACFKQLKEKVEKEYGVRIMPSSLDDRRGSRPRSMVRSFTMPSSSRPLSVASVSSLSSDSTP
SRPGSDGFALEPLLPKKMHSRSQDKLDKDDLEKEKKDKKKEKRNSKHQEIFEKEFKPTDISLQQSEAVILSETISPLRPQRPKSQVMNVI
GSERRFSVSPSSPSSQQTPPPVTPRAKLSFSMQSSLELNGMTGADVADVPPPLPLKGSVADYGNLMENQDLLGSPTPPPPPPHQRHLPPP

--------------------------------------------------------------
>89072_89072_3_TAPBP-DOCK1_TAPBP_chr6_33280993_ENST00000456592_DOCK1_chr10_128768965_ENST00000280333_length(transcript)=7457nt_BP=815nt
GGGGACGCGGCACAGATAGGGGGAAGCCGGAGTAATGGTTTTCGGGCAAGTGGATGTTGGAGAGCACACACAGGAGTTGGGGGGCGGGGG
AGGGCCTGGGGTTGGGGAGGGCTCGAACTCGGGGCTGCTGGGTAGTCCAGGAGGGCGCGGTAAGGCTGGGGTGTCCTGGTGAGAACTGGA
GAGGATCTACCCGGGTCCCTGCCTGGCCAGTGGGGAAACACCGGTCCCCCAGGCACCTTCACCTAACCAGAGCGGGGATTTCCACCGCCC
CTCATGCCGCCCTTTGGAGGAAAGTGAAAGTGAAAGGAGGAAGAGGAGGCTTCATGGCTGAGGAGGTCGCAGCGCCATGAAGTCCCTGTC
TCTGCTCCTCGCTGTGGCTTTGGGCCTGGCGACCGCCGTCTCAGCAGGACCCGCGGTGATCGAGTGTTGGTTCGTGGAGGATGCGAGCGG
AAAGGGCCTGGCCAAGAGACCCGGTGCACTGCTGTTGCGCCAGGGACCGGGGGAACCGCCGCCCCGGCCGGACCTCGACCCTGAGCTCTA
TCTCAGTGTACACGACCCCGCGGGCGCCCTCCAGGCTGCCTTCAGGCGGTATCCCCGGGGCGCCCCCGCACCACACTGCGAGATGAGCCG
CTTCGTGCCTCTCCCCGCCTCTGCGAAATGGGCCAGCGGCCTGACCCCCGCGCAGAACTGCCCGCGGGCCCTGGATGGGGCTTGGCTGAT
GGTCAGCATATCCAGCCCAGTCCTCAGCCTCTCCAGCCTCTTGCGACCACAGCCAGAGCCTCAGCAGGAGCCTGTTCTCATCACCATGGC
AACAGCTTTTTATAACTATGATGCCAGAGGAGCGGATGAACTTTCTTTACAGATCGGAGACACTGTGCACATCTTAGAAACATATGAAGG
GTGGTACCGAGGTTACACGTTACGAAAAAAGTCTAAGAAGGGTATATTTCCTGCTTCATATATTCATCTTAAAGAAGCGATAGTTGAAGG
AAAAGGGCAACATGAAACAGTCATCCCGGGTGACCTCCCCCTCATCCAGGAAGTCACCACGACACTCCGAGAGTGGTCCACCATCTGGAG
GCAGCTCTACGTGCAAGATAACAGGGAGATGTTTCGAAGTGTGCGGCACATGATCTATGACCTTATTGAATGGCGATCACAAATTCTTTC
TGGAACTCTGCCTCAGGATGAACTCAAAGAACTGAAGAAGAAGGTCACAGCCAAAATTGATTATGGAAACAGAATTCTAGATTTGGACCT
GGTGGTTAGAGATGAAGATGGGAATATTTTGGATCCAGAATTAACTAGCACGATTAGTCTCTTCAGAGCTCATGAAATAGCTTCTAAACA
AGTGGAGGAAAGGTTACAAGAGGAAAAATCTCAAAAGCAGAACATAGATATTAACAGACAAGCCAAGTTTGCTGCAACCCCTTCTCTGGC
CTTGTTTGTGAACCTCAAAAATGTGGTTTGTAAAATAGGAGAAGATGCTGAAGTCCTCATGTCTCTATATGACCCTGTGGAGTCCAAATT
CATCAGTGAGAACTACCTGGTTCGCTGGTCCAGTTCAGGATTACCTAAAGACATAGACAGATTACATAATTTGCGAGCCGTGTTTACTGA
CCTCGGAAGCAAAGACCTGAAAAGGGAGAAAATCAGTTTTGTCTGTCAGATTGTTCGCGTGGGTCGCATGGAGCTGAGGGACAACAACAC
CAGGAAACTGACCTCGGGGTTGCGGCGACCTTTTGGAGTGGCTGTGATGGATGTAACAGATATAATAAATGGAAAAGTAGATGATGAAGA
TAAGCAGCATTTCATTCCCTTTCAGCCGGTGGCAGGGGAGAATGACTTCCTTCAGACTGTTATAAACAAAGTCATCGCTGCCAAAGAAGT
CAACCACAAGGGGCAGGGTTTGTGGGTAACATTGAAATTACTTCCTGGAGATATCCATCAGATCCGAAAAGAGTTTCCGCATTTAGTGGA
CAGGACCACAGCTGTGGCTCGAAAAACAGGGTTTCCGGAGATAATCATGCCTGGTGATGTTCGAAATGATATCTATGTAACATTAGTTCA
AGGAGATTTTGATAAAGGAAGCAAAACAACAGCGAAGAACGTGGAGGTCACGGTGTCTGTGTACGATGAGGATGGGAAACGATTAGAGCA
TGTGATTTTCCCGGGTGCTGGTGATGAAGCGATTTCAGAGTACAAATCTGTGATTTACTACCAAGTAAAGCAGCCACGCTGGTTTGAGAC
TGTTAAGGTGGCCATTCCCATCGAGGACGTTAACCGCAGTCACCTTCGGTTTACCTTCCGCCACAGGTCATCACAGGACTCTAAGGATAA
ATCTGAGAAAATATTTGCACTAGCATTTGTCAAGCTGATGAGATACGATGGTACCACCCTGCGAGACGGAGAGCACGATCTTATCGTCTA
TAAGGCCGAAGCAAAGAAGCTGGAAGATGCTGCCACGTACTTGAGTCTGCCCTCCACGAAGGCAGAGTTGGAAGAAAAGGGCCACTCGGC
CACCGGCAAGAGCATGCAGAGCCTTGGGAGCTGCACCATTAGCAAGGACTCCTTCCAGATCTCCACGCTCGTGTGCTCCACCAAACTGAC
TCAGAACGTGGACCTTCTGGGGCTCTTGAAATGGCGCTCCAACACCAGCCTGCTGCAGCAGAACTTGAGGCAGCTGATGAAAGTCGATGG
TGGTGAAGTAGTGAAGTTTCTTCAGGACACGTTGGATGCCCTCTTCAACATCATGATGGAGAACTCAGAGAGTGAGACTTTTGACACGTT
AGTCTTTGATGCTCTGGTATTTATCATTGGACTGATTGCTGATAGAAAATTTCAGCATTTTAATCCTGTTTTGGAAACTTACATTAAGAA
ACACTTTAGTGCAACGTTAGCCTACACGAAGTTGACAAAAGTGTTGAAGAACTACGTGGACGGTGCTGAGAAGCCGGGAGTAAATGAGCA
GCTGTACAAAGCCATGAAAGCGCTAGAATCCATCTTCAAGTTCATCGTGCGCTCCAGGATCCTGTTCAATCAACTGTATGAAAACAAGGG
AGAGGCTGACTTCGTGGAATCTTTGCTGCAGCTCTTCAGGTCCATCAATGACATGATGAGCAGCATGTCAGACCAGACCGTCCGGGTGAA
GGGGGCAGCACTGAAATACTTACCAACGATCGTCAACGATGTGAAATTGGTGTTTGATCCCAAAGAGCTCAGCAAAATGTTTACTGAATT
CATCCTCAATGTTCCCATGGGCTTGCTGACCATCCAGAAACTCTACTGCTTGATCGAAATCGTCCACAGTGACCTCTTCACACAGCATGA
CTGCAGAGAGATCCTGCTTCCCATGATGACCGATCAGCTCAAGTACCATCTGGAGAGACAGGAGGACCTGGAGGCCTGCTGTCAGCTGCT
CAGCCACATCCTGGAGGTGCTGTACAGGAAGGACGTGGGGCCAACCCAGAGGCACGTCCAGATTATCATGGAGAAACTTCTCCGGACCGT
GAACCGAACCGTCATTTCCATGGGACGAGATTCTGAACTCATTGGAAACTTCGTGGCTTGCATGACAGCTATTTTACGACAAATGGAAGA
TTACCATTATGCCCACTTGATCAAGACTTTTGGGAAAATGAGGACTGATGTGGTAGATTTCCTAATGGAAACATTCATCATGTTTAAGAA
CCTCATTGGAAAGAACGTTTACCCCTTCGACTGGGTGATCATGAACATGGTGCAAAATAAAGTCTTCCTGCGAGCAATTAATCAGTATGC
AGATATGCTGAACAAAAAATTTCTGGATCAAGCCAACTTTGAGCTACAGCTGTGGAACAACTACTTTCACCTGGCTGTTGCTTTCCTTAC
TCAAGAGTCCCTGCAACTGGAGAATTTTTCAAGTGCCAAGAGAGCCAAAATCCTTAACAAGTACGGAGATATGAGGAGACAGATTGGCTT
TGAAATCAGAGACATGTGGTACAACCTTGGTCAACACAAGATAAAGTTCATTCCAGAAATGGTGGGCCCAATATTAGAAATGACATTAAT
TCCCGAGACGGAGCTGCGCAAAGCCACCATCCCCATCTTCTTTGATATGATGCAGTGTGAATTCCATTCGACCCGAAGCTTCCAAATGTT
TGAAAATGAGATCATCACCAAGCTGGATCATGAAGTCGAAGGAGGCAGAGGAGACGAACAGTACAAAGTGTTATTTGATAAAATCCTTCT
GGAACACTGCAGGAAGCACAAATACCTCGCCAAAACAGGAGAAACTTTTGTAAAACTCGTTGTGCGCTTAATGGAAAGGCTTTTGGATTA
TAGAACCATCATGCACGACGAGAACAAAGAAAACCGCATGAGCTGCACCGTCAATGTGCTGAATTTCTACAAAGAAATTGAAAGAGAAGA
AATGTATATAAGGTATTTGTACAAGCTCTGTGACCTGCACAAGGAGTGTGATAACTACACCGAAGCGGCTTACACCTTGCTTCTCCATGC
AAAGCTTCTTAAGTGGTCGGAGGATGTGTGTGTGGCCCACCTCACCCAGCGGGACGGGTACCAGGCCACCACGCAGGGACAGCTGAAGGA
GCAGCTCTACCAGGAAATCATCCACTACTTCGACAAAGGCAAGATGTGGGAGGAGGCCATTGCCTTGGGCAAGGAGCTAGCCGAGCAGTA
TGAGAACGAAATGTTTGATTATGAGCAACTCAGCGAATTGCTGAAAAAACAGGCTCAGTTTTATGAAAACATCGTCAAAGTGATCAGGCC
CAAGCCTGACTATTTTGCTGTTGGCTACTACGGACAAGGGTTCCCCACATTCCTGCGGGGAAAAGTTTTCATTTACCGAGGGAAAGAGTA
TGAGCGCCGGGAAGATTTTGAGGCTCGGCTCTTAACTCAGTTTCCAAACGCCGAGAAAATGAAGACAACATCTCCACCAGGCGACGATAT
TAAAAACTCTCCTGGCCAGTATATTCAGTGCTTCACAGTGAAGCCCAAACTCGATCTGCCTCCTAAGTTTCACAGGCCAGTGTCAGAGCA
GATTGTAAGTTTTTACAGGGTGAACGAGGTCCAGCGATTTGAATATTCTCGGCCAATCCGGAAGGGAGAGAAAAACCCAGACAATGAATT
TGCGAATATGTGGATCGAGAGAACCATATATACAACTGCATATAAATTACCTGGAATTTTAAGGTGGTTTGAGGTCAAGTCTGTTTTCAT
GGTGGAAATCAGCCCCCTGGAGAATGCCATTGAGACCATGCAGCTGACGAACGACAAGATCAACAGCATGGTGCAGCAGCACCTGGATGA
CCCCAGCCTGCCCATCAACCCGCTCTCCATGCTCCTGAACGGCATCGTGGACCCAGCTGTCATGGGGGGCTTCGCAAACTACGAAAAGGC
CTTCTTTACAGACCGGTACCTGCAGGAGCACCCTGAGGCCCATGAAAAGATCGAGAAGCTCAAGGACCTGATTGCTTGGCAGATTCCTTT
TCTGGCCGAAGGGATCAGAATCCATGGAGACAAAGTCACGGAGGCACTGAGGCCGTTCCACGAGAGGATGGAGGCCTGTTTCAAACAGCT
GAAGGAAAAGGTGGAGAAAGAGTACGGCGTCCGAATCATGCCCTCAAGTCTGGATGATAGAAGAGGCAGCCGCCCCCGGTCCATGGTGCG
GTCCTTCACGATGCCTTCCTCATCCCGCCCTCTGTCTGTGGCCTCTGTCTCTTCCCTCTCATCGGACAGCACCCCTTCCAGACCAGGCTC
CGACGGGTTTGCCCTGGAGCCTCTCCTGCCAAAGAAAATGCACTCCAGGTCCCAGGACAAGCTGGACAAGGATGACCTGGAGAAGGAGAA
GAAGGACAAGAAGAAGGAAAAAAGGAACAGCAAACATCAAGAGATATTTGAGAAAGAATTTAAACCCACCGACATTTCCCTGCAGCAGTC
TGAGGCTGTGATCCTTTCGGAAACGATAAGTCCCCTGCGGCCCCAGAGACCGAAGAGCCAGGTGATGAACGTCATTGGAAGCGAAAGGCG
CTTCTCGGTGTCCCCCTCGTCACCGTCCTCCCAGCAAACACCCCCTCCAGTTACACCAAGGGCCAAGCTCAGCTTCAGCATGCAGTCGAG
CTTGGAGCTGAACGGCATGACGGGGGCGGACGTGGCCGATGTCCCACCCCCTCTGCCTCTCAAAGGCAGCGTGGCAGATTACGGGAATTT
GATGGAAAACCAGGACTTGCTGGGCTCGCCAACACCTCCACCTCCCCCTCCACACCAGAGGCATCTGCCACCTCCACTGCCCAGCAAAAC
TCCGCCTCCTCCCCCTCCAAAGACAACTCGCAAGCAGGCATCGGTGGACTCCGGGATCGTGCAGTGACGTCGCAAGCCTCTCTGGAAAGA
GTGTGCTGCCCCTCCCCATCTCCATGCCCTCTCCTTCTGTGTCCCCTGAGTCTGCTGTTTACCTCATTGGGCCTGTGATGTTAACATTTC
GTGCGACTGCTTTTTCTTCAAAGGAGTTCAGTTCTCACCATGGAGTGAGTGGCCTTTAGCGTCATGGAGCAAGGTGGGTCTGGGAGGTAG
ATATGGGTCCGGGATGTGCTATCGTAGTTATCAGAGTTGGGGGCCTCTGAGTGTGTCTGGCTCTGAGAGAGTCTGAGTCTTGCCCAAACA
TTCTTTCTTTTTGTGCCAAATGACTTGCATTTGCAAAGAGCTCAATTGCTCTGAGCTCAGCCAAGTAGGAGAGGCTAGGCCATCACTCTT
AGGAAGCTGTGTAGTGATGATGTATAAGAATCCTCCTCACTGTCATGGGATGTTGTATCCAGCCCCTCCTTGTTCCAGCCGGTGGTGTGA
CTTCGTTGGTTGAGGTGTGTCTCCAACCTACATCAGACCATGAAGTTCAACCCCTCCAGGGAAGCTCCTGATTTCCCCTGCATAATTGAA
AATAGGATATTTCTCAGCTATTGAACAGTTACTAATTTATGGGGTGGAAACAGCATTAAGAATACTGAATCAAATGGAAAAACAAATGAA
TACAGGAAGATAAGTGTTCGTTCTTTTCTGAAAAAGAGTATGTGTACCACAAGAGCTGGTTTTAATTGGGTGAATTGTTTTTGTCCTCAT
TCTGTACAGAAATTTGTATATATGATGGTTCTTAGAACTTGTTTTAATTTTTGTGGTCCTTCCGTTTATTATAATAGGCGTCCACCAATG
ATTATCCATATGTGTTCTTAATTTTTAACTGCTGGAAGTGTTAAAACACACACACACACACACACACATTTTTTTTTTGAGAACTCCAAA
GTCCTGAAAATTTTGGTGGACAATGATTTTTAAAAAACTAACTTTGTATAACCTAATATTTGTATTCTCTCATCTATATTTTTTTATTCA

>89072_89072_3_TAPBP-DOCK1_TAPBP_chr6_33280993_ENST00000456592_DOCK1_chr10_128768965_ENST00000280333_length(amino acids)=2006AA_BP=155
MKSLSLLLAVALGLATAVSAGPAVIECWFVEDASGKGLAKRPGALLLRQGPGEPPPRPDLDPELYLSVHDPAGALQAAFRRYPRGAPAPH
CEMSRFVPLPASAKWASGLTPAQNCPRALDGAWLMVSISSPVLSLSSLLRPQPEPQQEPVLITMATAFYNYDARGADELSLQIGDTVHIL
ETYEGWYRGYTLRKKSKKGIFPASYIHLKEAIVEGKGQHETVIPGDLPLIQEVTTTLREWSTIWRQLYVQDNREMFRSVRHMIYDLIEWR
SQILSGTLPQDELKELKKKVTAKIDYGNRILDLDLVVRDEDGNILDPELTSTISLFRAHEIASKQVEERLQEEKSQKQNIDINRQAKFAA
TPSLALFVNLKNVVCKIGEDAEVLMSLYDPVESKFISENYLVRWSSSGLPKDIDRLHNLRAVFTDLGSKDLKREKISFVCQIVRVGRMEL
RDNNTRKLTSGLRRPFGVAVMDVTDIINGKVDDEDKQHFIPFQPVAGENDFLQTVINKVIAAKEVNHKGQGLWVTLKLLPGDIHQIRKEF
PHLVDRTTAVARKTGFPEIIMPGDVRNDIYVTLVQGDFDKGSKTTAKNVEVTVSVYDEDGKRLEHVIFPGAGDEAISEYKSVIYYQVKQP
RWFETVKVAIPIEDVNRSHLRFTFRHRSSQDSKDKSEKIFALAFVKLMRYDGTTLRDGEHDLIVYKAEAKKLEDAATYLSLPSTKAELEE
KGHSATGKSMQSLGSCTISKDSFQISTLVCSTKLTQNVDLLGLLKWRSNTSLLQQNLRQLMKVDGGEVVKFLQDTLDALFNIMMENSESE
TFDTLVFDALVFIIGLIADRKFQHFNPVLETYIKKHFSATLAYTKLTKVLKNYVDGAEKPGVNEQLYKAMKALESIFKFIVRSRILFNQL
YENKGEADFVESLLQLFRSINDMMSSMSDQTVRVKGAALKYLPTIVNDVKLVFDPKELSKMFTEFILNVPMGLLTIQKLYCLIEIVHSDL
FTQHDCREILLPMMTDQLKYHLERQEDLEACCQLLSHILEVLYRKDVGPTQRHVQIIMEKLLRTVNRTVISMGRDSELIGNFVACMTAIL
RQMEDYHYAHLIKTFGKMRTDVVDFLMETFIMFKNLIGKNVYPFDWVIMNMVQNKVFLRAINQYADMLNKKFLDQANFELQLWNNYFHLA
VAFLTQESLQLENFSSAKRAKILNKYGDMRRQIGFEIRDMWYNLGQHKIKFIPEMVGPILEMTLIPETELRKATIPIFFDMMQCEFHSTR
SFQMFENEIITKLDHEVEGGRGDEQYKVLFDKILLEHCRKHKYLAKTGETFVKLVVRLMERLLDYRTIMHDENKENRMSCTVNVLNFYKE
IEREEMYIRYLYKLCDLHKECDNYTEAAYTLLLHAKLLKWSEDVCVAHLTQRDGYQATTQGQLKEQLYQEIIHYFDKGKMWEEAIALGKE
LAEQYENEMFDYEQLSELLKKQAQFYENIVKVIRPKPDYFAVGYYGQGFPTFLRGKVFIYRGKEYERREDFEARLLTQFPNAEKMKTTSP
PGDDIKNSPGQYIQCFTVKPKLDLPPKFHRPVSEQIVSFYRVNEVQRFEYSRPIRKGEKNPDNEFANMWIERTIYTTAYKLPGILRWFEV
KSVFMVEISPLENAIETMQLTNDKINSMVQQHLDDPSLPINPLSMLLNGIVDPAVMGGFANYEKAFFTDRYLQEHPEAHEKIEKLKDLIA
WQIPFLAEGIRIHGDKVTEALRPFHERMEACFKQLKEKVEKEYGVRIMPSSLDDRRGSRPRSMVRSFTMPSSSRPLSVASVSSLSSDSTP
SRPGSDGFALEPLLPKKMHSRSQDKLDKDDLEKEKKDKKKEKRNSKHQEIFEKEFKPTDISLQQSEAVILSETISPLRPQRPKSQVMNVI
GSERRFSVSPSSPSSQQTPPPVTPRAKLSFSMQSSLELNGMTGADVADVPPPLPLKGSVADYGNLMENQDLLGSPTPPPPPPHQRHLPPP

--------------------------------------------------------------
>89072_89072_4_TAPBP-DOCK1_TAPBP_chr6_33280993_ENST00000475304_DOCK1_chr10_128768965_ENST00000280333_length(transcript)=7321nt_BP=679nt
CCAGGAGGGCGCGGTAAGGCTGGGGTGTCCTGGTGAGAACTGGAGAGGATCTACCCGGGTCCCTGCCTGGCCAGTGGGGAAACACCGGTC
CCCCAGGCACCTTCACCTAACCAGAGCGGGGATTTCCACCGCCCCTCATGCCGCCCTTTGGAGGAAAGTGAAAGTGAAAGGAGGAAGAGG
AGGCTTCATGGCTGAGGAGGTCGCAGCGCCATGAAGTCCCTGTCTCTGCTCCTCGCTGTGGCTTTGGGCCTGGCGACCGCCGTCTCAGCA
GGACCCGCGGTGATCGAGTGTTGGTTCGTGGAGGATGCGAGCGGAAAGGGCCTGGCCAAGAGACCCGGTGCACTGCTGTTGCGCCAGGGA
CCGGGGGAACCGCCGCCCCGGCCGGACCTCGACCCTGAGCTCTATCTCAGTGTACACGACCCCGCGGGCGCCCTCCAGGCTGCCTTCAGG
CGGTATCCCCGGGGCGCCCCCGCACCACACTGCGAGATGAGCCGCTTCGTGCCTCTCCCCGCCTCTGCGAAATGGGCCAGCGGCCTGACC
CCCGCGCAGAACTGCCCGCGGGCCCTGGATGGGGCTTGGCTGATGGTCAGCATATCCAGCCCAGTCCTCAGCCTCTCCAGCCTCTTGCGA
CCACAGCCAGAGCCTCAGCAGGAGCCTGTTCTCATCACCATGGCAACAGCTTTTTATAACTATGATGCCAGAGGAGCGGATGAACTTTCT
TTACAGATCGGAGACACTGTGCACATCTTAGAAACATATGAAGGGTGGTACCGAGGTTACACGTTACGAAAAAAGTCTAAGAAGGGTATA
TTTCCTGCTTCATATATTCATCTTAAAGAAGCGATAGTTGAAGGAAAAGGGCAACATGAAACAGTCATCCCGGGTGACCTCCCCCTCATC
CAGGAAGTCACCACGACACTCCGAGAGTGGTCCACCATCTGGAGGCAGCTCTACGTGCAAGATAACAGGGAGATGTTTCGAAGTGTGCGG
CACATGATCTATGACCTTATTGAATGGCGATCACAAATTCTTTCTGGAACTCTGCCTCAGGATGAACTCAAAGAACTGAAGAAGAAGGTC
ACAGCCAAAATTGATTATGGAAACAGAATTCTAGATTTGGACCTGGTGGTTAGAGATGAAGATGGGAATATTTTGGATCCAGAATTAACT
AGCACGATTAGTCTCTTCAGAGCTCATGAAATAGCTTCTAAACAAGTGGAGGAAAGGTTACAAGAGGAAAAATCTCAAAAGCAGAACATA
GATATTAACAGACAAGCCAAGTTTGCTGCAACCCCTTCTCTGGCCTTGTTTGTGAACCTCAAAAATGTGGTTTGTAAAATAGGAGAAGAT
GCTGAAGTCCTCATGTCTCTATATGACCCTGTGGAGTCCAAATTCATCAGTGAGAACTACCTGGTTCGCTGGTCCAGTTCAGGATTACCT
AAAGACATAGACAGATTACATAATTTGCGAGCCGTGTTTACTGACCTCGGAAGCAAAGACCTGAAAAGGGAGAAAATCAGTTTTGTCTGT
CAGATTGTTCGCGTGGGTCGCATGGAGCTGAGGGACAACAACACCAGGAAACTGACCTCGGGGTTGCGGCGACCTTTTGGAGTGGCTGTG
ATGGATGTAACAGATATAATAAATGGAAAAGTAGATGATGAAGATAAGCAGCATTTCATTCCCTTTCAGCCGGTGGCAGGGGAGAATGAC
TTCCTTCAGACTGTTATAAACAAAGTCATCGCTGCCAAAGAAGTCAACCACAAGGGGCAGGGTTTGTGGGTAACATTGAAATTACTTCCT
GGAGATATCCATCAGATCCGAAAAGAGTTTCCGCATTTAGTGGACAGGACCACAGCTGTGGCTCGAAAAACAGGGTTTCCGGAGATAATC
ATGCCTGGTGATGTTCGAAATGATATCTATGTAACATTAGTTCAAGGAGATTTTGATAAAGGAAGCAAAACAACAGCGAAGAACGTGGAG
GTCACGGTGTCTGTGTACGATGAGGATGGGAAACGATTAGAGCATGTGATTTTCCCGGGTGCTGGTGATGAAGCGATTTCAGAGTACAAA
TCTGTGATTTACTACCAAGTAAAGCAGCCACGCTGGTTTGAGACTGTTAAGGTGGCCATTCCCATCGAGGACGTTAACCGCAGTCACCTT
CGGTTTACCTTCCGCCACAGGTCATCACAGGACTCTAAGGATAAATCTGAGAAAATATTTGCACTAGCATTTGTCAAGCTGATGAGATAC
GATGGTACCACCCTGCGAGACGGAGAGCACGATCTTATCGTCTATAAGGCCGAAGCAAAGAAGCTGGAAGATGCTGCCACGTACTTGAGT
CTGCCCTCCACGAAGGCAGAGTTGGAAGAAAAGGGCCACTCGGCCACCGGCAAGAGCATGCAGAGCCTTGGGAGCTGCACCATTAGCAAG
GACTCCTTCCAGATCTCCACGCTCGTGTGCTCCACCAAACTGACTCAGAACGTGGACCTTCTGGGGCTCTTGAAATGGCGCTCCAACACC
AGCCTGCTGCAGCAGAACTTGAGGCAGCTGATGAAAGTCGATGGTGGTGAAGTAGTGAAGTTTCTTCAGGACACGTTGGATGCCCTCTTC
AACATCATGATGGAGAACTCAGAGAGTGAGACTTTTGACACGTTAGTCTTTGATGCTCTGGTATTTATCATTGGACTGATTGCTGATAGA
AAATTTCAGCATTTTAATCCTGTTTTGGAAACTTACATTAAGAAACACTTTAGTGCAACGTTAGCCTACACGAAGTTGACAAAAGTGTTG
AAGAACTACGTGGACGGTGCTGAGAAGCCGGGAGTAAATGAGCAGCTGTACAAAGCCATGAAAGCGCTAGAATCCATCTTCAAGTTCATC
GTGCGCTCCAGGATCCTGTTCAATCAACTGTATGAAAACAAGGGAGAGGCTGACTTCGTGGAATCTTTGCTGCAGCTCTTCAGGTCCATC
AATGACATGATGAGCAGCATGTCAGACCAGACCGTCCGGGTGAAGGGGGCAGCACTGAAATACTTACCAACGATCGTCAACGATGTGAAA
TTGGTGTTTGATCCCAAAGAGCTCAGCAAAATGTTTACTGAATTCATCCTCAATGTTCCCATGGGCTTGCTGACCATCCAGAAACTCTAC
TGCTTGATCGAAATCGTCCACAGTGACCTCTTCACACAGCATGACTGCAGAGAGATCCTGCTTCCCATGATGACCGATCAGCTCAAGTAC
CATCTGGAGAGACAGGAGGACCTGGAGGCCTGCTGTCAGCTGCTCAGCCACATCCTGGAGGTGCTGTACAGGAAGGACGTGGGGCCAACC
CAGAGGCACGTCCAGATTATCATGGAGAAACTTCTCCGGACCGTGAACCGAACCGTCATTTCCATGGGACGAGATTCTGAACTCATTGGA
AACTTCGTGGCTTGCATGACAGCTATTTTACGACAAATGGAAGATTACCATTATGCCCACTTGATCAAGACTTTTGGGAAAATGAGGACT
GATGTGGTAGATTTCCTAATGGAAACATTCATCATGTTTAAGAACCTCATTGGAAAGAACGTTTACCCCTTCGACTGGGTGATCATGAAC
ATGGTGCAAAATAAAGTCTTCCTGCGAGCAATTAATCAGTATGCAGATATGCTGAACAAAAAATTTCTGGATCAAGCCAACTTTGAGCTA
CAGCTGTGGAACAACTACTTTCACCTGGCTGTTGCTTTCCTTACTCAAGAGTCCCTGCAACTGGAGAATTTTTCAAGTGCCAAGAGAGCC
AAAATCCTTAACAAGTACGGAGATATGAGGAGACAGATTGGCTTTGAAATCAGAGACATGTGGTACAACCTTGGTCAACACAAGATAAAG
TTCATTCCAGAAATGGTGGGCCCAATATTAGAAATGACATTAATTCCCGAGACGGAGCTGCGCAAAGCCACCATCCCCATCTTCTTTGAT
ATGATGCAGTGTGAATTCCATTCGACCCGAAGCTTCCAAATGTTTGAAAATGAGATCATCACCAAGCTGGATCATGAAGTCGAAGGAGGC
AGAGGAGACGAACAGTACAAAGTGTTATTTGATAAAATCCTTCTGGAACACTGCAGGAAGCACAAATACCTCGCCAAAACAGGAGAAACT
TTTGTAAAACTCGTTGTGCGCTTAATGGAAAGGCTTTTGGATTATAGAACCATCATGCACGACGAGAACAAAGAAAACCGCATGAGCTGC
ACCGTCAATGTGCTGAATTTCTACAAAGAAATTGAAAGAGAAGAAATGTATATAAGGTATTTGTACAAGCTCTGTGACCTGCACAAGGAG
TGTGATAACTACACCGAAGCGGCTTACACCTTGCTTCTCCATGCAAAGCTTCTTAAGTGGTCGGAGGATGTGTGTGTGGCCCACCTCACC
CAGCGGGACGGGTACCAGGCCACCACGCAGGGACAGCTGAAGGAGCAGCTCTACCAGGAAATCATCCACTACTTCGACAAAGGCAAGATG
TGGGAGGAGGCCATTGCCTTGGGCAAGGAGCTAGCCGAGCAGTATGAGAACGAAATGTTTGATTATGAGCAACTCAGCGAATTGCTGAAA
AAACAGGCTCAGTTTTATGAAAACATCGTCAAAGTGATCAGGCCCAAGCCTGACTATTTTGCTGTTGGCTACTACGGACAAGGGTTCCCC
ACATTCCTGCGGGGAAAAGTTTTCATTTACCGAGGGAAAGAGTATGAGCGCCGGGAAGATTTTGAGGCTCGGCTCTTAACTCAGTTTCCA
AACGCCGAGAAAATGAAGACAACATCTCCACCAGGCGACGATATTAAAAACTCTCCTGGCCAGTATATTCAGTGCTTCACAGTGAAGCCC
AAACTCGATCTGCCTCCTAAGTTTCACAGGCCAGTGTCAGAGCAGATTGTAAGTTTTTACAGGGTGAACGAGGTCCAGCGATTTGAATAT
TCTCGGCCAATCCGGAAGGGAGAGAAAAACCCAGACAATGAATTTGCGAATATGTGGATCGAGAGAACCATATATACAACTGCATATAAA
TTACCTGGAATTTTAAGGTGGTTTGAGGTCAAGTCTGTTTTCATGGTGGAAATCAGCCCCCTGGAGAATGCCATTGAGACCATGCAGCTG
ACGAACGACAAGATCAACAGCATGGTGCAGCAGCACCTGGATGACCCCAGCCTGCCCATCAACCCGCTCTCCATGCTCCTGAACGGCATC
GTGGACCCAGCTGTCATGGGGGGCTTCGCAAACTACGAAAAGGCCTTCTTTACAGACCGGTACCTGCAGGAGCACCCTGAGGCCCATGAA
AAGATCGAGAAGCTCAAGGACCTGATTGCTTGGCAGATTCCTTTTCTGGCCGAAGGGATCAGAATCCATGGAGACAAAGTCACGGAGGCA
CTGAGGCCGTTCCACGAGAGGATGGAGGCCTGTTTCAAACAGCTGAAGGAAAAGGTGGAGAAAGAGTACGGCGTCCGAATCATGCCCTCA
AGTCTGGATGATAGAAGAGGCAGCCGCCCCCGGTCCATGGTGCGGTCCTTCACGATGCCTTCCTCATCCCGCCCTCTGTCTGTGGCCTCT
GTCTCTTCCCTCTCATCGGACAGCACCCCTTCCAGACCAGGCTCCGACGGGTTTGCCCTGGAGCCTCTCCTGCCAAAGAAAATGCACTCC
AGGTCCCAGGACAAGCTGGACAAGGATGACCTGGAGAAGGAGAAGAAGGACAAGAAGAAGGAAAAAAGGAACAGCAAACATCAAGAGATA
TTTGAGAAAGAATTTAAACCCACCGACATTTCCCTGCAGCAGTCTGAGGCTGTGATCCTTTCGGAAACGATAAGTCCCCTGCGGCCCCAG
AGACCGAAGAGCCAGGTGATGAACGTCATTGGAAGCGAAAGGCGCTTCTCGGTGTCCCCCTCGTCACCGTCCTCCCAGCAAACACCCCCT
CCAGTTACACCAAGGGCCAAGCTCAGCTTCAGCATGCAGTCGAGCTTGGAGCTGAACGGCATGACGGGGGCGGACGTGGCCGATGTCCCA
CCCCCTCTGCCTCTCAAAGGCAGCGTGGCAGATTACGGGAATTTGATGGAAAACCAGGACTTGCTGGGCTCGCCAACACCTCCACCTCCC
CCTCCACACCAGAGGCATCTGCCACCTCCACTGCCCAGCAAAACTCCGCCTCCTCCCCCTCCAAAGACAACTCGCAAGCAGGCATCGGTG
GACTCCGGGATCGTGCAGTGACGTCGCAAGCCTCTCTGGAAAGAGTGTGCTGCCCCTCCCCATCTCCATGCCCTCTCCTTCTGTGTCCCC
TGAGTCTGCTGTTTACCTCATTGGGCCTGTGATGTTAACATTTCGTGCGACTGCTTTTTCTTCAAAGGAGTTCAGTTCTCACCATGGAGT
GAGTGGCCTTTAGCGTCATGGAGCAAGGTGGGTCTGGGAGGTAGATATGGGTCCGGGATGTGCTATCGTAGTTATCAGAGTTGGGGGCCT
CTGAGTGTGTCTGGCTCTGAGAGAGTCTGAGTCTTGCCCAAACATTCTTTCTTTTTGTGCCAAATGACTTGCATTTGCAAAGAGCTCAAT
TGCTCTGAGCTCAGCCAAGTAGGAGAGGCTAGGCCATCACTCTTAGGAAGCTGTGTAGTGATGATGTATAAGAATCCTCCTCACTGTCAT
GGGATGTTGTATCCAGCCCCTCCTTGTTCCAGCCGGTGGTGTGACTTCGTTGGTTGAGGTGTGTCTCCAACCTACATCAGACCATGAAGT
TCAACCCCTCCAGGGAAGCTCCTGATTTCCCCTGCATAATTGAAAATAGGATATTTCTCAGCTATTGAACAGTTACTAATTTATGGGGTG
GAAACAGCATTAAGAATACTGAATCAAATGGAAAAACAAATGAATACAGGAAGATAAGTGTTCGTTCTTTTCTGAAAAAGAGTATGTGTA
CCACAAGAGCTGGTTTTAATTGGGTGAATTGTTTTTGTCCTCATTCTGTACAGAAATTTGTATATATGATGGTTCTTAGAACTTGTTTTA
ATTTTTGTGGTCCTTCCGTTTATTATAATAGGCGTCCACCAATGATTATCCATATGTGTTCTTAATTTTTAACTGCTGGAAGTGTTAAAA
CACACACACACACACACACACATTTTTTTTTTGAGAACTCCAAAGTCCTGAAAATTTTGGTGGACAATGATTTTTAAAAAACTAACTTTG
TATAACCTAATATTTGTATTCTCTCATCTATATTTTTTTATTCACTATAATCATGATACTCTTCTAATAGACTTAAAAGTTAATCATTGA

>89072_89072_4_TAPBP-DOCK1_TAPBP_chr6_33280993_ENST00000475304_DOCK1_chr10_128768965_ENST00000280333_length(amino acids)=2006AA_BP=155
MKSLSLLLAVALGLATAVSAGPAVIECWFVEDASGKGLAKRPGALLLRQGPGEPPPRPDLDPELYLSVHDPAGALQAAFRRYPRGAPAPH
CEMSRFVPLPASAKWASGLTPAQNCPRALDGAWLMVSISSPVLSLSSLLRPQPEPQQEPVLITMATAFYNYDARGADELSLQIGDTVHIL
ETYEGWYRGYTLRKKSKKGIFPASYIHLKEAIVEGKGQHETVIPGDLPLIQEVTTTLREWSTIWRQLYVQDNREMFRSVRHMIYDLIEWR
SQILSGTLPQDELKELKKKVTAKIDYGNRILDLDLVVRDEDGNILDPELTSTISLFRAHEIASKQVEERLQEEKSQKQNIDINRQAKFAA
TPSLALFVNLKNVVCKIGEDAEVLMSLYDPVESKFISENYLVRWSSSGLPKDIDRLHNLRAVFTDLGSKDLKREKISFVCQIVRVGRMEL
RDNNTRKLTSGLRRPFGVAVMDVTDIINGKVDDEDKQHFIPFQPVAGENDFLQTVINKVIAAKEVNHKGQGLWVTLKLLPGDIHQIRKEF
PHLVDRTTAVARKTGFPEIIMPGDVRNDIYVTLVQGDFDKGSKTTAKNVEVTVSVYDEDGKRLEHVIFPGAGDEAISEYKSVIYYQVKQP
RWFETVKVAIPIEDVNRSHLRFTFRHRSSQDSKDKSEKIFALAFVKLMRYDGTTLRDGEHDLIVYKAEAKKLEDAATYLSLPSTKAELEE
KGHSATGKSMQSLGSCTISKDSFQISTLVCSTKLTQNVDLLGLLKWRSNTSLLQQNLRQLMKVDGGEVVKFLQDTLDALFNIMMENSESE
TFDTLVFDALVFIIGLIADRKFQHFNPVLETYIKKHFSATLAYTKLTKVLKNYVDGAEKPGVNEQLYKAMKALESIFKFIVRSRILFNQL
YENKGEADFVESLLQLFRSINDMMSSMSDQTVRVKGAALKYLPTIVNDVKLVFDPKELSKMFTEFILNVPMGLLTIQKLYCLIEIVHSDL
FTQHDCREILLPMMTDQLKYHLERQEDLEACCQLLSHILEVLYRKDVGPTQRHVQIIMEKLLRTVNRTVISMGRDSELIGNFVACMTAIL
RQMEDYHYAHLIKTFGKMRTDVVDFLMETFIMFKNLIGKNVYPFDWVIMNMVQNKVFLRAINQYADMLNKKFLDQANFELQLWNNYFHLA
VAFLTQESLQLENFSSAKRAKILNKYGDMRRQIGFEIRDMWYNLGQHKIKFIPEMVGPILEMTLIPETELRKATIPIFFDMMQCEFHSTR
SFQMFENEIITKLDHEVEGGRGDEQYKVLFDKILLEHCRKHKYLAKTGETFVKLVVRLMERLLDYRTIMHDENKENRMSCTVNVLNFYKE
IEREEMYIRYLYKLCDLHKECDNYTEAAYTLLLHAKLLKWSEDVCVAHLTQRDGYQATTQGQLKEQLYQEIIHYFDKGKMWEEAIALGKE
LAEQYENEMFDYEQLSELLKKQAQFYENIVKVIRPKPDYFAVGYYGQGFPTFLRGKVFIYRGKEYERREDFEARLLTQFPNAEKMKTTSP
PGDDIKNSPGQYIQCFTVKPKLDLPPKFHRPVSEQIVSFYRVNEVQRFEYSRPIRKGEKNPDNEFANMWIERTIYTTAYKLPGILRWFEV
KSVFMVEISPLENAIETMQLTNDKINSMVQQHLDDPSLPINPLSMLLNGIVDPAVMGGFANYEKAFFTDRYLQEHPEAHEKIEKLKDLIA
WQIPFLAEGIRIHGDKVTEALRPFHERMEACFKQLKEKVEKEYGVRIMPSSLDDRRGSRPRSMVRSFTMPSSSRPLSVASVSSLSSDSTP
SRPGSDGFALEPLLPKKMHSRSQDKLDKDDLEKEKKDKKKEKRNSKHQEIFEKEFKPTDISLQQSEAVILSETISPLRPQRPKSQVMNVI
GSERRFSVSPSSPSSQQTPPPVTPRAKLSFSMQSSLELNGMTGADVADVPPPLPLKGSVADYGNLMENQDLLGSPTPPPPPPHQRHLPPP

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Fusion Gene PPI Analysis for TAPBP-DOCK1

Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in
ChiPPI page.

Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)

Hgene

Hgene's interactors

Tgene

Tgene's interactors

- Retained PPIs in in-frame fusion.

Partner	Gene	Hbp	Tbp	ENST	Strand	BPexon	TotalExon	Protein feature loci	*BPloci	TotalLen	Still interaction with
Tgene	DOCK1	chr6:33280993	chr10:128768965	ENST00000280333		0	52	1837_1852	15.333333333333334	1866.0	NCK2 (minor)
Tgene	DOCK1	chr6:33280993	chr10:128768965	ENST00000280333		0	52	1793_1819	15.333333333333334	1866.0	NCK2 second and third SH3 domain (minor)
Tgene	DOCK1	chr6:33280993	chr10:128768965	ENST00000280333		0	52	1820_1836	15.333333333333334	1866.0	NCK2 third SH3 domain (major)

- Lost PPIs in in-frame fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Interaction lost with

- Retained PPIs, but lost function due to frame-shift fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Interaction lost with

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Related Drugs for TAPBP-DOCK1

Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)

Partner

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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Related Diseases for TAPBP-DOCK1

Diseases associated with fusion partners.
(DisGeNet 4.0)

Partner

Gene

Disease ID

Disease name

# pubmeds

Source