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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:TAPBPL-SON (FusionGDB2 ID:89078)

Fusion Gene Summary for TAPBPL-SON

check button Fusion gene summary
Fusion gene informationFusion gene name: TAPBPL-SON
Fusion gene ID: 89078
HgeneTgene
Gene symbol

TAPBPL

SON

Gene ID

55080

6651

Gene nameTAP binding protein likeSON DNA and RNA binding protein
SynonymsTAPBP-R|TAPBPRBASS1|C21orf50|DBP-5|NREBP|SON3|TOKIMS
Cytomap

12p13.31

21q22.11

Type of geneprotein-codingprotein-coding
Descriptiontapasin-related proteinTAP binding protein relatedTAP-binding protein-related proteinTAPASIN-Rtapasin-likeprotein SONBax antagonist selected in Saccharomyces 1NRE-binding proteinSON DNA binding proteinnegative regulatory element-binding protein
Modification date2020032020200313
UniProtAcc.

SHH

Ensembl transtripts involved in fusion geneENST00000545700, ENST00000266556, 
ENST00000544021, 		ENST00000290239, 
ENST00000356577, ENST00000300278, 
ENST00000381679, ENST00000381692, 
ENST00000470533, 
Fusion gene scores* DoF score6 X 6 X 2=7216 X 15 X 5=1200
# samples 616
** MAII scorelog2(6/72*10)=-0.263034405833794
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(16/1200*10)=-2.90689059560852
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: TAPBPL [Title/Abstract] AND SON [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointTAPBPL(6562443)-SON(34925063), # samples:1
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneTAPBPL

GO:0002502

peptide antigen assembly with MHC class I protein complex

26869717

HgeneTAPBPL

GO:0002590

negative regulation of antigen processing and presentation of peptide antigen via MHC class I

23401559

TgeneSON

GO:0006397

mRNA processing

21504830

TgeneSON

GO:0043066

negative regulation of apoptotic process

10509013

TgeneSON

GO:0048024

regulation of mRNA splicing, via spliceosome

21504830


check buttonFusion gene breakpoints across TAPBPL (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across SON (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChiTaRS5.0N/ADB201269TAPBPLchr12

6562443

+SONchr21

34925063

+


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Fusion Gene ORF analysis for TAPBPL-SON

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
3UTR-3CDSENST00000545700ENST00000290239TAPBPLchr12

6562443

+SONchr21

34925063

+
3UTR-3CDSENST00000545700ENST00000356577TAPBPLchr12

6562443

+SONchr21

34925063

+
3UTR-intronENST00000545700ENST00000300278TAPBPLchr12

6562443

+SONchr21

34925063

+
3UTR-intronENST00000545700ENST00000381679TAPBPLchr12

6562443

+SONchr21

34925063

+
3UTR-intronENST00000545700ENST00000381692TAPBPLchr12

6562443

+SONchr21

34925063

+
3UTR-intronENST00000545700ENST00000470533TAPBPLchr12

6562443

+SONchr21

34925063

+
5CDS-intronENST00000266556ENST00000300278TAPBPLchr12

6562443

+SONchr21

34925063

+
5CDS-intronENST00000266556ENST00000381679TAPBPLchr12

6562443

+SONchr21

34925063

+
5CDS-intronENST00000266556ENST00000381692TAPBPLchr12

6562443

+SONchr21

34925063

+
5CDS-intronENST00000266556ENST00000470533TAPBPLchr12

6562443

+SONchr21

34925063

+
In-frameENST00000266556ENST00000290239TAPBPLchr12

6562443

+SONchr21

34925063

+
In-frameENST00000266556ENST00000356577TAPBPLchr12

6562443

+SONchr21

34925063

+
intron-3CDSENST00000544021ENST00000290239TAPBPLchr12

6562443

+SONchr21

34925063

+
intron-3CDSENST00000544021ENST00000356577TAPBPLchr12

6562443

+SONchr21

34925063

+
intron-intronENST00000544021ENST00000300278TAPBPLchr12

6562443

+SONchr21

34925063

+
intron-intronENST00000544021ENST00000381679TAPBPLchr12

6562443

+SONchr21

34925063

+
intron-intronENST00000544021ENST00000381692TAPBPLchr12

6562443

+SONchr21

34925063

+
intron-intronENST00000544021ENST00000470533TAPBPLchr12

6562443

+SONchr21

34925063

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000266556TAPBPLchr126562443+ENST00000356577SONchr2134925063+506124918240031273
ENST00000266556TAPBPLchr126562443+ENST00000290239SONchr2134925063+516624918237001172

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000266556ENST00000356577TAPBPLchr126562443+SONchr2134925063+0.0006276910.9993723
ENST00000266556ENST00000290239TAPBPLchr126562443+SONchr2134925063+0.0009549010.9990451

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Fusion Genomic Features for TAPBPL-SON


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for TAPBPL-SON


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr12:6562443/chr21:34925063)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
.SON

SHH

FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.462

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneSONchr12:6562443chr21:34925063ENST000002902390132305_23510699.6666666666666DomainG-patch
TgeneSONchr12:6562443chr21:34925063ENST000002902390132371_24260699.6666666666666DomainDRBM
TgeneSONchr12:6562443chr21:34925063ENST00000300278072305_235102304.0DomainG-patch
TgeneSONchr12:6562443chr21:34925063ENST00000300278072371_242602304.0DomainDRBM
TgeneSONchr12:6562443chr21:34925063ENST000003565770122305_235102427.0DomainG-patch
TgeneSONchr12:6562443chr21:34925063ENST000003565770122371_242602427.0DomainDRBM
TgeneSONchr12:6562443chr21:34925063ENST00000381679052305_235102109.0DomainG-patch
TgeneSONchr12:6562443chr21:34925063ENST00000381679052371_242602109.0DomainDRBM
TgeneSONchr12:6562443chr21:34925063ENST000002902390131006_11260699.6666666666666RegionNote=14 X 6 AA repeats of [ED]-R-S-M-M-S
TgeneSONchr12:6562443chr21:34925063ENST000002902390131147_11790699.6666666666666RegionNote=3 X 11 AA tandem repats of P-P-L-P-P-E-E-P-P-[TME]-[MTG]
TgeneSONchr12:6562443chr21:34925063ENST000002902390131359_13900699.6666666666666RegionNote=4 X 8 AA tandem repeats of V-L-E-SS-[AVT]-VT
TgeneSONchr12:6562443chr21:34925063ENST000002902390131925_19940699.6666666666666RegionNote=7 X 7 AA repeats of P-S-R-R-S-R-[TS]
TgeneSONchr12:6562443chr21:34925063ENST000002902390131934_20130699.6666666666666RegionNote=2 X 19 AA repeats of P-S-R-R-R-R-S-R-S-V-V-R-R-R-S-F-S-I-S
TgeneSONchr12:6562443chr21:34925063ENST000002902390132013_20390699.6666666666666RegionNote=3 X tandem repeats of [ST]-P-[VLI]-R-[RL]-[RK]-[RF]-S-R
TgeneSONchr12:6562443chr21:34925063ENST00000290239013726_8950699.6666666666666RegionNote=17 X 10 AA tandem repeats of L-A-[ST]-[NSG]-[TS]-MDSQM
TgeneSONchr12:6562443chr21:34925063ENST00000290239013912_9880699.6666666666666RegionNote=11 X 7 AA tandem repeats of [DR]-P-Y-R-[LI][AG][QHP]
TgeneSONchr12:6562443chr21:34925063ENST00000300278071006_112602304.0RegionNote=14 X 6 AA repeats of [ED]-R-S-M-M-S
TgeneSONchr12:6562443chr21:34925063ENST00000300278071147_117902304.0RegionNote=3 X 11 AA tandem repats of P-P-L-P-P-E-E-P-P-[TME]-[MTG]
TgeneSONchr12:6562443chr21:34925063ENST00000300278071359_139002304.0RegionNote=4 X 8 AA tandem repeats of V-L-E-SS-[AVT]-VT
TgeneSONchr12:6562443chr21:34925063ENST00000300278071925_199402304.0RegionNote=7 X 7 AA repeats of P-S-R-R-S-R-[TS]
TgeneSONchr12:6562443chr21:34925063ENST00000300278071934_201302304.0RegionNote=2 X 19 AA repeats of P-S-R-R-R-R-S-R-S-V-V-R-R-R-S-F-S-I-S
TgeneSONchr12:6562443chr21:34925063ENST00000300278072013_203902304.0RegionNote=3 X tandem repeats of [ST]-P-[VLI]-R-[RL]-[RK]-[RF]-S-R
TgeneSONchr12:6562443chr21:34925063ENST0000030027807726_89502304.0RegionNote=17 X 10 AA tandem repeats of L-A-[ST]-[NSG]-[TS]-MDSQM
TgeneSONchr12:6562443chr21:34925063ENST0000030027807912_98802304.0RegionNote=11 X 7 AA tandem repeats of [DR]-P-Y-R-[LI][AG][QHP]
TgeneSONchr12:6562443chr21:34925063ENST000003565770121006_112602427.0RegionNote=14 X 6 AA repeats of [ED]-R-S-M-M-S
TgeneSONchr12:6562443chr21:34925063ENST000003565770121147_117902427.0RegionNote=3 X 11 AA tandem repats of P-P-L-P-P-E-E-P-P-[TME]-[MTG]
TgeneSONchr12:6562443chr21:34925063ENST000003565770121359_139002427.0RegionNote=4 X 8 AA tandem repeats of V-L-E-SS-[AVT]-VT
TgeneSONchr12:6562443chr21:34925063ENST000003565770121925_199402427.0RegionNote=7 X 7 AA repeats of P-S-R-R-S-R-[TS]
TgeneSONchr12:6562443chr21:34925063ENST000003565770121934_201302427.0RegionNote=2 X 19 AA repeats of P-S-R-R-R-R-S-R-S-V-V-R-R-R-S-F-S-I-S
TgeneSONchr12:6562443chr21:34925063ENST000003565770122013_203902427.0RegionNote=3 X tandem repeats of [ST]-P-[VLI]-R-[RL]-[RK]-[RF]-S-R
TgeneSONchr12:6562443chr21:34925063ENST00000356577012726_89502427.0RegionNote=17 X 10 AA tandem repeats of L-A-[ST]-[NSG]-[TS]-MDSQM
TgeneSONchr12:6562443chr21:34925063ENST00000356577012912_98802427.0RegionNote=11 X 7 AA tandem repeats of [DR]-P-Y-R-[LI][AG][QHP]
TgeneSONchr12:6562443chr21:34925063ENST00000381679051006_112602109.0RegionNote=14 X 6 AA repeats of [ED]-R-S-M-M-S
TgeneSONchr12:6562443chr21:34925063ENST00000381679051147_117902109.0RegionNote=3 X 11 AA tandem repats of P-P-L-P-P-E-E-P-P-[TME]-[MTG]
TgeneSONchr12:6562443chr21:34925063ENST00000381679051359_139002109.0RegionNote=4 X 8 AA tandem repeats of V-L-E-SS-[AVT]-VT
TgeneSONchr12:6562443chr21:34925063ENST00000381679051925_199402109.0RegionNote=7 X 7 AA repeats of P-S-R-R-S-R-[TS]
TgeneSONchr12:6562443chr21:34925063ENST00000381679051934_201302109.0RegionNote=2 X 19 AA repeats of P-S-R-R-R-R-S-R-S-V-V-R-R-R-S-F-S-I-S
TgeneSONchr12:6562443chr21:34925063ENST00000381679052013_203902109.0RegionNote=3 X tandem repeats of [ST]-P-[VLI]-R-[RL]-[RK]-[RF]-S-R
TgeneSONchr12:6562443chr21:34925063ENST0000038167905726_89502109.0RegionNote=17 X 10 AA tandem repeats of L-A-[ST]-[NSG]-[TS]-MDSQM
TgeneSONchr12:6562443chr21:34925063ENST0000038167905912_98802109.0RegionNote=11 X 7 AA tandem repeats of [DR]-P-Y-R-[LI][AG][QHP]
TgeneSONchr12:6562443chr21:34925063ENST000002902390131006_10110699.6666666666666RepeatNote=1-1
TgeneSONchr12:6562443chr21:34925063ENST000002902390131014_10190699.6666666666666RepeatNote=1-2
TgeneSONchr12:6562443chr21:34925063ENST000002902390131021_10260699.6666666666666RepeatNote=1-3
TgeneSONchr12:6562443chr21:34925063ENST000002902390131030_10350699.6666666666666RepeatNote=1-4
TgeneSONchr12:6562443chr21:34925063ENST000002902390131038_10430699.6666666666666RepeatNote=1-5
TgeneSONchr12:6562443chr21:34925063ENST000002902390131046_10510699.6666666666666RepeatNote=1-6
TgeneSONchr12:6562443chr21:34925063ENST000002902390131055_10600699.6666666666666RepeatNote=1-7
TgeneSONchr12:6562443chr21:34925063ENST000002902390131063_10680699.6666666666666RepeatNote=1-8
TgeneSONchr12:6562443chr21:34925063ENST000002902390131071_10760699.6666666666666RepeatNote=1-9
TgeneSONchr12:6562443chr21:34925063ENST000002902390131080_10850699.6666666666666RepeatNote=1-10
TgeneSONchr12:6562443chr21:34925063ENST000002902390131089_10940699.6666666666666RepeatNote=1-11
TgeneSONchr12:6562443chr21:34925063ENST000002902390131100_11050699.6666666666666RepeatNote=1-12
TgeneSONchr12:6562443chr21:34925063ENST000002902390131111_11160699.6666666666666RepeatNote=1-13
TgeneSONchr12:6562443chr21:34925063ENST000002902390131121_11260699.6666666666666RepeatNote=1-14
TgeneSONchr12:6562443chr21:34925063ENST000002902390131925_19310699.6666666666666RepeatNote=2-1
TgeneSONchr12:6562443chr21:34925063ENST000002902390131934_19520699.6666666666666RepeatNote=3-1
TgeneSONchr12:6562443chr21:34925063ENST000002902390131953_19590699.6666666666666RepeatNote=2-2
TgeneSONchr12:6562443chr21:34925063ENST000002902390131960_19660699.6666666666666RepeatNote=2-3
TgeneSONchr12:6562443chr21:34925063ENST000002902390131967_19730699.6666666666666RepeatNote=2-4
TgeneSONchr12:6562443chr21:34925063ENST000002902390131974_19800699.6666666666666RepeatNote=2-5
TgeneSONchr12:6562443chr21:34925063ENST000002902390131981_19870699.6666666666666RepeatNote=2-6
TgeneSONchr12:6562443chr21:34925063ENST000002902390131988_19940699.6666666666666RepeatNote=2-7
TgeneSONchr12:6562443chr21:34925063ENST000002902390131995_20130699.6666666666666RepeatNote=3-2
TgeneSONchr12:6562443chr21:34925063ENST00000300278071006_101102304.0RepeatNote=1-1
TgeneSONchr12:6562443chr21:34925063ENST00000300278071014_101902304.0RepeatNote=1-2
TgeneSONchr12:6562443chr21:34925063ENST00000300278071021_102602304.0RepeatNote=1-3
TgeneSONchr12:6562443chr21:34925063ENST00000300278071030_103502304.0RepeatNote=1-4
TgeneSONchr12:6562443chr21:34925063ENST00000300278071038_104302304.0RepeatNote=1-5
TgeneSONchr12:6562443chr21:34925063ENST00000300278071046_105102304.0RepeatNote=1-6
TgeneSONchr12:6562443chr21:34925063ENST00000300278071055_106002304.0RepeatNote=1-7
TgeneSONchr12:6562443chr21:34925063ENST00000300278071063_106802304.0RepeatNote=1-8
TgeneSONchr12:6562443chr21:34925063ENST00000300278071071_107602304.0RepeatNote=1-9
TgeneSONchr12:6562443chr21:34925063ENST00000300278071080_108502304.0RepeatNote=1-10
TgeneSONchr12:6562443chr21:34925063ENST00000300278071089_109402304.0RepeatNote=1-11
TgeneSONchr12:6562443chr21:34925063ENST00000300278071100_110502304.0RepeatNote=1-12
TgeneSONchr12:6562443chr21:34925063ENST00000300278071111_111602304.0RepeatNote=1-13
TgeneSONchr12:6562443chr21:34925063ENST00000300278071121_112602304.0RepeatNote=1-14
TgeneSONchr12:6562443chr21:34925063ENST00000300278071925_193102304.0RepeatNote=2-1
TgeneSONchr12:6562443chr21:34925063ENST00000300278071934_195202304.0RepeatNote=3-1
TgeneSONchr12:6562443chr21:34925063ENST00000300278071953_195902304.0RepeatNote=2-2
TgeneSONchr12:6562443chr21:34925063ENST00000300278071960_196602304.0RepeatNote=2-3
TgeneSONchr12:6562443chr21:34925063ENST00000300278071967_197302304.0RepeatNote=2-4
TgeneSONchr12:6562443chr21:34925063ENST00000300278071974_198002304.0RepeatNote=2-5
TgeneSONchr12:6562443chr21:34925063ENST00000300278071981_198702304.0RepeatNote=2-6
TgeneSONchr12:6562443chr21:34925063ENST00000300278071988_199402304.0RepeatNote=2-7
TgeneSONchr12:6562443chr21:34925063ENST00000300278071995_201302304.0RepeatNote=3-2
TgeneSONchr12:6562443chr21:34925063ENST000003565770121006_101102427.0RepeatNote=1-1
TgeneSONchr12:6562443chr21:34925063ENST000003565770121014_101902427.0RepeatNote=1-2
TgeneSONchr12:6562443chr21:34925063ENST000003565770121021_102602427.0RepeatNote=1-3
TgeneSONchr12:6562443chr21:34925063ENST000003565770121030_103502427.0RepeatNote=1-4
TgeneSONchr12:6562443chr21:34925063ENST000003565770121038_104302427.0RepeatNote=1-5
TgeneSONchr12:6562443chr21:34925063ENST000003565770121046_105102427.0RepeatNote=1-6
TgeneSONchr12:6562443chr21:34925063ENST000003565770121055_106002427.0RepeatNote=1-7
TgeneSONchr12:6562443chr21:34925063ENST000003565770121063_106802427.0RepeatNote=1-8
TgeneSONchr12:6562443chr21:34925063ENST000003565770121071_107602427.0RepeatNote=1-9
TgeneSONchr12:6562443chr21:34925063ENST000003565770121080_108502427.0RepeatNote=1-10
TgeneSONchr12:6562443chr21:34925063ENST000003565770121089_109402427.0RepeatNote=1-11
TgeneSONchr12:6562443chr21:34925063ENST000003565770121100_110502427.0RepeatNote=1-12
TgeneSONchr12:6562443chr21:34925063ENST000003565770121111_111602427.0RepeatNote=1-13
TgeneSONchr12:6562443chr21:34925063ENST000003565770121121_112602427.0RepeatNote=1-14
TgeneSONchr12:6562443chr21:34925063ENST000003565770121925_193102427.0RepeatNote=2-1
TgeneSONchr12:6562443chr21:34925063ENST000003565770121934_195202427.0RepeatNote=3-1
TgeneSONchr12:6562443chr21:34925063ENST000003565770121953_195902427.0RepeatNote=2-2
TgeneSONchr12:6562443chr21:34925063ENST000003565770121960_196602427.0RepeatNote=2-3
TgeneSONchr12:6562443chr21:34925063ENST000003565770121967_197302427.0RepeatNote=2-4
TgeneSONchr12:6562443chr21:34925063ENST000003565770121974_198002427.0RepeatNote=2-5
TgeneSONchr12:6562443chr21:34925063ENST000003565770121981_198702427.0RepeatNote=2-6
TgeneSONchr12:6562443chr21:34925063ENST000003565770121988_199402427.0RepeatNote=2-7
TgeneSONchr12:6562443chr21:34925063ENST000003565770121995_201302427.0RepeatNote=3-2
TgeneSONchr12:6562443chr21:34925063ENST00000381679051006_101102109.0RepeatNote=1-1
TgeneSONchr12:6562443chr21:34925063ENST00000381679051014_101902109.0RepeatNote=1-2
TgeneSONchr12:6562443chr21:34925063ENST00000381679051021_102602109.0RepeatNote=1-3
TgeneSONchr12:6562443chr21:34925063ENST00000381679051030_103502109.0RepeatNote=1-4
TgeneSONchr12:6562443chr21:34925063ENST00000381679051038_104302109.0RepeatNote=1-5
TgeneSONchr12:6562443chr21:34925063ENST00000381679051046_105102109.0RepeatNote=1-6
TgeneSONchr12:6562443chr21:34925063ENST00000381679051055_106002109.0RepeatNote=1-7
TgeneSONchr12:6562443chr21:34925063ENST00000381679051063_106802109.0RepeatNote=1-8
TgeneSONchr12:6562443chr21:34925063ENST00000381679051071_107602109.0RepeatNote=1-9
TgeneSONchr12:6562443chr21:34925063ENST00000381679051080_108502109.0RepeatNote=1-10
TgeneSONchr12:6562443chr21:34925063ENST00000381679051089_109402109.0RepeatNote=1-11
TgeneSONchr12:6562443chr21:34925063ENST00000381679051100_110502109.0RepeatNote=1-12
TgeneSONchr12:6562443chr21:34925063ENST00000381679051111_111602109.0RepeatNote=1-13
TgeneSONchr12:6562443chr21:34925063ENST00000381679051121_112602109.0RepeatNote=1-14
TgeneSONchr12:6562443chr21:34925063ENST00000381679051925_193102109.0RepeatNote=2-1
TgeneSONchr12:6562443chr21:34925063ENST00000381679051934_195202109.0RepeatNote=3-1
TgeneSONchr12:6562443chr21:34925063ENST00000381679051953_195902109.0RepeatNote=2-2
TgeneSONchr12:6562443chr21:34925063ENST00000381679051960_196602109.0RepeatNote=2-3
TgeneSONchr12:6562443chr21:34925063ENST00000381679051967_197302109.0RepeatNote=2-4
TgeneSONchr12:6562443chr21:34925063ENST00000381679051974_198002109.0RepeatNote=2-5
TgeneSONchr12:6562443chr21:34925063ENST00000381679051981_198702109.0RepeatNote=2-6
TgeneSONchr12:6562443chr21:34925063ENST00000381679051988_199402109.0RepeatNote=2-7
TgeneSONchr12:6562443chr21:34925063ENST00000381679051995_201302109.0RepeatNote=3-2

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneTAPBPLchr12:6562443chr21:34925063ENST00000266556+17181_2970469.0DomainNote=Ig-like V-type
HgeneTAPBPLchr12:6562443chr21:34925063ENST00000266556+17304_3940469.0DomainNote=Ig-like C1-type
HgeneTAPBPLchr12:6562443chr21:34925063ENST00000266556+1719_4050469.0Topological domainLumenal
HgeneTAPBPLchr12:6562443chr21:34925063ENST00000266556+17427_4680469.0Topological domainCytoplasmic
HgeneTAPBPLchr12:6562443chr21:34925063ENST00000266556+17406_4260469.0TransmembraneHelical


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Fusion Gene Sequence for TAPBPL-SON


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>89078_89078_1_TAPBPL-SON_TAPBPL_chr12_6562443_ENST00000266556_SON_chr21_34925063_ENST00000290239_length(transcript)=5166nt_BP=249nt
GTGAAAGTGAAAGAAAAGTCGGCAGCAGAGGGAACAGGGAAGAAACCTAAAGGCTGCAGGCTGCCAGGTGTGCTTGGAGAGCCCCCTTCT
TCCGCCGGGCCTCGCAAGCAGCGTAGGACTGTGGAGAAGGGCGGTGGGCAAGGAGGGAACTCGAGAGCAGCCTCCATGGGCACACAGGAG
GGCTGGTGCCTGCTGCTCTGCCTGGCTCTATCTGGAGCAGCAGAAACCATATTATCTTTGAGGCCTCAGCACCAGAGGGTCCAGCATTGC
CCACTGAGCAGTCAGCATTAACAGCTGAAAATACTTGGCCTACAGAGGTGCCATCATCACCATCTGAAGAGTCTGTATCGCAGCCTGAGC
CTCCTGTGAGTCAAAGTGAGATTTCGGAGCCTTCAGCAGTGCCTACTGATTATTCAGTGTCAGCATCAGATCCCTCAGTTTTAGTATCAG
AGGCTGCTGTGACTGTTCCAGAACCACCACCAGAGCCAGAATCTTCAATTACGTTAACACCTGTAGAGTCTGCAGTAGTAGCAGAAGAAC
ATGAAGTTGTTCCAGAGAGACCAGTGACTTGTATGGTATCTGAAACTCCCGCCATGTCAGCTGAACCAACTGTGTTAGCATCAGAGCCTC
CTGTTATGTCAGAGACAGCAGAAACATTTGATTCCATGAGAGCCTCAGGACATGTTGCCTCAGAAGTATCTACATCCTTGTTGGTTCCAG
CAGTAACTACTCCAGTGCTGGCAGAGAGCATTCTGGAGCCGCCAGCCATGGCTGCCCCAGAGTCTTCAGCTATGGCTGTCCTGGAGTCTT
CGGCTGTGACCGTCCTGGAGTCTTCGACTGTGACTGTCCTGGAGTCTTCGACTGTAACTGTCCTGGAGCCTTCGGTTGTGACTGTCCCGG
AGCCTCCTGTTGTGGCTGAGCCAGACTATGTTACCATTCCTGTGCCAGTTGTTTCTGCGCTGGAGCCTTCTGTGCCTGTTCTGGAACCAG
CGGTGTCAGTCCTTCAACCTTCTATGATTGTTTCAGAACCATCTGTTTCTGTCCAGGAATCGACTGTGACAGTTTCAGAGCCTGCTGTCA
CAGTCTCAGAGCAGACTCAAGTAATACCAACTGAGGTGGCTATAGAGTCCACACCAATGATACTGGAATCTAGTATCATGTCATCACATG
TTATGAAAGGAATTAATCTATCCTCTGGTGATCAAAATCTTGCTCCAGAGATTGGCATGCAGGAGATTGCATTGCATTCAGGTGAAGAAC
CACATGCTGAGGAACACCTGAAAGGTGACTTTTACGAAAGTGAACATGGTATAAATATAGACCTTAATATAAATAATCATTTAATTGCTA
AAGAGATGGAACATAATACAGTGTGTGCTGCTGGTACTAGTCCTGTTGGGGAAATTGGTGAAGAGAAAATTTTGCCCACCAGTGAGACTA
AACAGCGCACAGTATTGGATACCTACCCTGGTGTTAGTGAAGCTGATGCAGGAGAAACTCTATCTTCTACTGGTCCTTTTGCTCTGGAAC
CTGATGCAACAGGAACTAGTAAGGGTATTGAATTTACCACAGCATCTACTCTCAGTTTAGTTAATAAATATGATGTTGATTTATCTTTAA
CTACTCAAGATACTGAACATGACATGGTAATTTCCACCAGTCCTAGTGGTGGTAGTGAAGCTGACATTGAAGGGCCTTTGCCTGCTAAAG
ATATTCATCTTGATTTACCATCTAATAATAACCTTGTTAGTAAGGATACAGAAGAACCATTACCTGTAAAAGAGAGTGACCAGACATTAG
CAGCTCTGCTCAGCCCTAAAGAAAGTAGTGGAGGAGAAAAAGAAGTACCTCCCCCTCCTAAAGAGACACTGCCTGATTCAGGATTTTCTG
CCAATATTGAGGATATTAATGAAGCAGATTTAGTGAGACCGTTACTTCCTAAGGACATGGAACGTCTTACAAGCCTTAGAGCTGGCATTG
AAGGACCTTTACTTGCAAGTGATGTTGGACGTGACAGATCTGCTGCCAGCCCGGTTGTAAGTAGTATGCCAGAAAGAGCTTCAGAGTCTT
CTTCAGAGGAAAAAGATGATTATGAAATTTTTGTAAAAGTTAAGGACACTCACGAAAAAAGCAAGAAAAATAAGAACCGTGATAAGGGGG
AGAAAGAGAAGAAAAGAGACTCTTCATTAAGATCTCGAAGTAAGCGTTCCAAATCTTCTGAACACAAATCACGCAAGCGTACCAGTGAAT
CTCGTTCTAGGGCAAGAAAGAGATCATCTAAGTCCAAGTCTCATCGCTCTCAGACACGTTCACGGTCACGTTCAAGACGCAGGAGGAGAA
GCAGCAGATCAAGATCAAAGTCTAGAGGAAGAAGATCTGTATCAAAAGAGAAGCGCAAAAGATCTCCAAAGCACAGATCCAAGTCTAGGG
AAAGAAAAAGAAAAAGATCAAGCTCCAGGGATAACCGAAAGACAGTTAGAGCTCGAAGTCGAACCCCAAGTCGTCGGAGTCGGAGTCATA
CTCCAAGTCGTCGACGAAGGTCTAGATCTGTGGGTAGAAGAAGGAGCTTTAGCATTTCCCCAAGCCGCCGCAGCCGCACCCCCAGCCGCC
GCAGCCGCACCCCCAGCCGCCGCAGCCGCACCCCCAGCCGCCGCAGCCGCACCCCCAGCCGCCGGAGCCGCACCCCTAGCCGTCGGAGCC
GCACCCCAAGCCGCCGGAGAAGATCAAGGTCTGTGGTAAGAAGACGAAGCTTCAGTATCTCACCAGTCAGATTAAGGCGATCAAGAACAC
CCTTAAGAAGAAGGTTTAGCAGATCTCCCATCCGTCGTAAAAGATCCAGGTCTTCTGAACGAGGCAGATCACCCAAACGTCTGACAGATT
TGGATAAGGCTCAATTACTTGAAATAGCCAAAGCTAATGCAGCTGCCATGTGTGCTAAGGCTGGTGTCCCTTTACCACCAAACCTAAAGC
CTGCACCTCCACCTACTATAGAAGAGAAAGTTGCTAAAAAGTCAGGAGGAGCTACTATAGAAGAACTAACTGAGAAATGTAAACAGATCG
CACAGAGTAAAGAAGATGATGATGTAATAGTGAATAAACCTCATGTTTCGGATGAAGAGGAAGAAGAACCTCCTTTTTATCATCATCCCT
TTAAACTCAGTGAACCCAAACCTATTTTTTTCAATCTGAATATTGCTGCAGCAAAACCAACTCCACCAAAAAGCCAGGTAACATTAACAA
AAGAATTCCCTGTATCATCTGGATCTCAACATCGGAAAAAAGAAGCGGATAGTGTTTATGGAGAATGGGTTCCTGTGGAGAAAAATGGTG
AAGAAAACAAAGATGATGATAATGTTTTCAGCAGCAATTTGCCCTCAGAGCCTGTGGACATCTCTACAGCAATGAGTGAACGGGCACTTG
CTCAGAAAAGACTCAGTGAGAATGCATTTGATCTTGAAGCCATGAGCATGTTAAATAGAGCTCAGGAAAGGATTGATGCCTGGGCTCAGC
TGAACTCTATTCCTGGCCAGTTCACAGGAAGTACAGGAGTACAGGTTTTGACACAAGAACAGTTGGCCAATACTGGTGCCCAAGCCTGGA
TTAAAAAGGGCCAAATCCTTGTAGCTGTCTTCTTGCCCCGGTCAGTGCCAGCCGTACTATTCACAACACTGCTGCTACCGAGGCCTAGGA
TCAGTTCTTAAGAGCAGCCCCGGTAACTGGAGGAATGGGAGCCGTTTTGATGAGAAAAATGGGCTGGAGAGAAGGAGAAGGATTAGGAAA
AAACAAAGAAGGCAATAAGGAACCCATCCTAGTTGATTTTAAGACAGACCGAAAAGGTCTTGTTGCAGTAGGAGAAAGAGCACAAAAGAG
GTCTGGGAACTTCTCTGCTGCAATGAAAGATCTGTCAGGCAAACATCCTGTGTCTGCTTTGATGGAGATCTGTAATAAAAGAAGGTGGCA
ACCACCTGAATTTCTATTGGTCCATGATAGTGGCCCTGATCATCGCAAACATTTTCTCTTTAGGGTATTGAGAAATGGAGCCCTTACCAG
ACCCAATTGTATGTTTTTCTTGAATAGGTATTGATAAATGGAAGCGCTTACCAGCCCAGCTTTGCCAGCCCTAATAAGAAGCATGCTAAA
GCCACAGCAGCTACTGTGGTTCTTCAAGCAATGGGCCTTGTACCAAAGGACCTCATGGCTAATGCCACTTGCTTCAGGAGTGCCTCACGT
AGATAGATTGAGGTTTTATAATAATCATTTCAGAATTTTACTCTGCATCACAATGTATTTCCTCTTTAATGTTGTAAATATTTGGCAATT
TAAGACATTGTGTAAAAAGCAATCTGTAAAAACATCTCCAGGCTTTGATTTTTGTACCATGGAAATTGTATTTAACCATACAGGGTTTTG
GTATGTTTATATTGTTTACCTTAGTGATGTATTTGTTTAAGTGGCTAACATCCAAACGACTGTTTGAAGGCATCAGAGTAATCTTCAGTG
TGGAATGTTAAATAACGCTTTTATACTGTATTTTGTACTATGATGTAACTCCCCTTCCTTATGGCTAGGCTACTGTAACACTTGCCTGTA
ATCAGTGAAGGGCTGTGCACCTTGTACTATTTCACAATGGGTTCTGCTGGACAGATAATGGGCCAGTGTTATTGAGGTGATCAAGATCTG
TTCCACAGGGCTAATGCCACCATCTCCCCTCAAAATTTTGTAGAGGTTCTAAAAAGAAAGTGGTATGTTGTGTGATGATCAGCACTAAGT
CCTGCATTCCTGTTAAAGCCACTTGGGTCATAAGAAGGGAGTAAAAAATGAAGTCTGACTAGAATTCTATTGCAGAGGCCAGTACATTTA
GTATGGCATTGAGTTGTGATATAGTTTTACTTTGATGTGCATTTTGAATTTCAGCTACACCTAGATAGACGTAAAATGATAATTAAAATG
CTGTAACCAACTTATCTAATAAAATTGGCAACCAGCCACTATTTTGTTGACTATGAGAAAGTTAAAAGTTTATGTTAATTTTTAGGGTCT
GATAGAATATTTCATGTGTATTACAGTGGTATTCATATGCTATGTCTCTAAACTTTATTTTCAAAAGCTTAAGGCCCAAATACAAACTTC

>89078_89078_1_TAPBPL-SON_TAPBPL_chr12_6562443_ENST00000266556_SON_chr21_34925063_ENST00000290239_length(amino acids)=1172AA_BP=734
MVPAALPGSIWSSRNHIIFEASAPEGPALPTEQSALTAENTWPTEVPSSPSEESVSQPEPPVSQSEISEPSAVPTDYSVSASDPSVLVSE
AAVTVPEPPPEPESSITLTPVESAVVAEEHEVVPERPVTCMVSETPAMSAEPTVLASEPPVMSETAETFDSMRASGHVASEVSTSLLVPA
VTTPVLAESILEPPAMAAPESSAMAVLESSAVTVLESSTVTVLESSTVTVLEPSVVTVPEPPVVAEPDYVTIPVPVVSALEPSVPVLEPA
VSVLQPSMIVSEPSVSVQESTVTVSEPAVTVSEQTQVIPTEVAIESTPMILESSIMSSHVMKGINLSSGDQNLAPEIGMQEIALHSGEEP
HAEEHLKGDFYESEHGINIDLNINNHLIAKEMEHNTVCAAGTSPVGEIGEEKILPTSETKQRTVLDTYPGVSEADAGETLSSTGPFALEP
DATGTSKGIEFTTASTLSLVNKYDVDLSLTTQDTEHDMVISTSPSGGSEADIEGPLPAKDIHLDLPSNNNLVSKDTEEPLPVKESDQTLA
ALLSPKESSGGEKEVPPPPKETLPDSGFSANIEDINEADLVRPLLPKDMERLTSLRAGIEGPLLASDVGRDRSAASPVVSSMPERASESS
SEEKDDYEIFVKVKDTHEKSKKNKNRDKGEKEKKRDSSLRSRSKRSKSSEHKSRKRTSESRSRARKRSSKSKSHRSQTRSRSRSRRRRRS
SRSRSKSRGRRSVSKEKRKRSPKHRSKSRERKRKRSSSRDNRKTVRARSRTPSRRSRSHTPSRRRRSRSVGRRRSFSISPSRRSRTPSRR
SRTPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRRRSRSVVRRRSFSISPVRLRRSRTPLRRRFSRSPIRRKRSRSSERGRSPKRLTDL
DKAQLLEIAKANAAAMCAKAGVPLPPNLKPAPPPTIEEKVAKKSGGATIEELTEKCKQIAQSKEDDDVIVNKPHVSDEEEEEPPFYHHPF
KLSEPKPIFFNLNIAAAKPTPPKSQVTLTKEFPVSSGSQHRKKEADSVYGEWVPVEKNGEENKDDDNVFSSNLPSEPVDISTAMSERALA
QKRLSENAFDLEAMSMLNRAQERIDAWAQLNSIPGQFTGSTGVQVLTQEQLANTGAQAWIKKGQILVAVFLPRSVPAVLFTTLLLPRPRI

--------------------------------------------------------------
>89078_89078_2_TAPBPL-SON_TAPBPL_chr12_6562443_ENST00000266556_SON_chr21_34925063_ENST00000356577_length(transcript)=5061nt_BP=249nt
GTGAAAGTGAAAGAAAAGTCGGCAGCAGAGGGAACAGGGAAGAAACCTAAAGGCTGCAGGCTGCCAGGTGTGCTTGGAGAGCCCCCTTCT
TCCGCCGGGCCTCGCAAGCAGCGTAGGACTGTGGAGAAGGGCGGTGGGCAAGGAGGGAACTCGAGAGCAGCCTCCATGGGCACACAGGAG
GGCTGGTGCCTGCTGCTCTGCCTGGCTCTATCTGGAGCAGCAGAAACCATATTATCTTTGAGGCCTCAGCACCAGAGGGTCCAGCATTGC
CCACTGAGCAGTCAGCATTAACAGCTGAAAATACTTGGCCTACAGAGGTGCCATCATCACCATCTGAAGAGTCTGTATCGCAGCCTGAGC
CTCCTGTGAGTCAAAGTGAGATTTCGGAGCCTTCAGCAGTGCCTACTGATTATTCAGTGTCAGCATCAGATCCCTCAGTTTTAGTATCAG
AGGCTGCTGTGACTGTTCCAGAACCACCACCAGAGCCAGAATCTTCAATTACGTTAACACCTGTAGAGTCTGCAGTAGTAGCAGAAGAAC
ATGAAGTTGTTCCAGAGAGACCAGTGACTTGTATGGTATCTGAAACTCCCGCCATGTCAGCTGAACCAACTGTGTTAGCATCAGAGCCTC
CTGTTATGTCAGAGACAGCAGAAACATTTGATTCCATGAGAGCCTCAGGACATGTTGCCTCAGAAGTATCTACATCCTTGTTGGTTCCAG
CAGTAACTACTCCAGTGCTGGCAGAGAGCATTCTGGAGCCGCCAGCCATGGCTGCCCCAGAGTCTTCAGCTATGGCTGTCCTGGAGTCTT
CGGCTGTGACCGTCCTGGAGTCTTCGACTGTGACTGTCCTGGAGTCTTCGACTGTAACTGTCCTGGAGCCTTCGGTTGTGACTGTCCCGG
AGCCTCCTGTTGTGGCTGAGCCAGACTATGTTACCATTCCTGTGCCAGTTGTTTCTGCGCTGGAGCCTTCTGTGCCTGTTCTGGAACCAG
CGGTGTCAGTCCTTCAACCTTCTATGATTGTTTCAGAACCATCTGTTTCTGTCCAGGAATCGACTGTGACAGTTTCAGAGCCTGCTGTCA
CAGTCTCAGAGCAGACTCAAGTAATACCAACTGAGGTGGCTATAGAGTCCACACCAATGATACTGGAATCTAGTATCATGTCATCACATG
TTATGAAAGGAATTAATCTATCCTCTGGTGATCAAAATCTTGCTCCAGAGATTGGCATGCAGGAGATTGCATTGCATTCAGGTGAAGAAC
CACATGCTGAGGAACACCTGAAAGGTGACTTTTACGAAAGTGAACATGGTATAAATATAGACCTTAATATAAATAATCATTTAATTGCTA
AAGAGATGGAACATAATACAGTGTGTGCTGCTGGTACTAGTCCTGTTGGGGAAATTGGTGAAGAGAAAATTTTGCCCACCAGTGAGACTA
AACAGCGCACAGTATTGGATACCTACCCTGGTGTTAGTGAAGCTGATGCAGGAGAAACTCTATCTTCTACTGGTCCTTTTGCTCTGGAAC
CTGATGCAACAGGAACTAGTAAGGGTATTGAATTTACCACAGCATCTACTCTCAGTTTAGTTAATAAATATGATGTTGATTTATCTTTAA
CTACTCAAGATACTGAACATGACATGGTAATTTCCACCAGTCCTAGTGGTGGTAGTGAAGCTGACATTGAAGGGCCTTTGCCTGCTAAAG
ATATTCATCTTGATTTACCATCTAATAATAACCTTGTTAGTAAGGATACAGAAGAACCATTACCTGTAAAAGAGAGTGACCAGACATTAG
CAGCTCTGCTCAGCCCTAAAGAAAGTAGTGGAGGAGAAAAAGAAGTACCTCCCCCTCCTAAAGAGACACTGCCTGATTCAGGATTTTCTG
CCAATATTGAGGATATTAATGAAGCAGATTTAGTGAGACCGTTACTTCCTAAGGACATGGAACGTCTTACAAGCCTTAGAGCTGGCATTG
AAGGACCTTTACTTGCAAGTGATGTTGGACGTGACAGATCTGCTGCCAGCCCGGTTGTAAGTAGTATGCCAGAAAGAGCTTCAGAGTCTT
CTTCAGAGGAAAAAGATGATTATGAAATTTTTGTAAAAGTTAAGGACACTCACGAAAAAAGCAAGAAAAATAAGAACCGTGATAAGGGGG
AGAAAGAGAAGAAAAGAGACTCTTCATTAAGATCTCGAAGTAAGCGTTCCAAATCTTCTGAACACAAATCACGCAAGCGTACCAGTGAAT
CTCGTTCTAGGGCAAGAAAGAGATCATCTAAGTCCAAGTCTCATCGCTCTCAGACACGTTCACGGTCACGTTCAAGACGCAGGAGGAGAA
GCAGCAGATCAAGATCAAAGTCTAGAGGAAGAAGATCTGTATCAAAAGAGAAGCGCAAAAGATCTCCAAAGCACAGATCCAAGTCTAGGG
AAAGAAAAAGAAAAAGATCAAGCTCCAGGGATAACCGAAAGACAGTTAGAGCTCGAAGTCGAACCCCAAGTCGTCGGAGTCGGAGTCATA
CTCCAAGTCGTCGACGAAGGTCTAGATCTGTGGGTAGAAGAAGGAGCTTTAGCATTTCCCCAAGCCGCCGCAGCCGCACCCCCAGCCGCC
GCAGCCGCACCCCCAGCCGCCGCAGCCGCACCCCCAGCCGCCGCAGCCGCACCCCCAGCCGCCGGAGCCGCACCCCTAGCCGTCGGAGCC
GCACCCCAAGCCGCCGGAGAAGATCAAGGTCTGTGGTAAGAAGACGAAGCTTCAGTATCTCACCAGTCAGATTAAGGCGATCAAGAACAC
CCTTAAGAAGAAGGTTTAGCAGATCTCCCATCCGTCGTAAAAGATCCAGGTCTTCTGAACGAGGCAGATCACCCAAACGTCTGACAGATT
TGGATAAGGCTCAATTACTTGAAATAGCCAAAGCTAATGCAGCTGCCATGTGTGCTAAGGCTGGTGTCCCTTTACCACCAAACCTAAAGC
CTGCACCTCCACCTACTATAGAAGAGAAAGTTGCTAAAAAGTCAGGAGGAGCTACTATAGAAGAACTAACTGAGAAATGTAAACAGATCG
CACAGAGTAAAGAAGATGATGATGTAATAGTGAATAAACCTCATGTTTCGGATGAAGAGGAAGAAGAACCTCCTTTTTATCATCATCCCT
TTAAACTCAGTGAACCCAAACCTATTTTTTTCAATCTGAATATTGCTGCAGCAAAACCAACTCCACCAAAAAGCCAGGTAACATTAACAA
AAGAATTCCCTGTATCATCTGGATCTCAACATCGGAAAAAAGAAGCGGATAGTGTTTATGGAGAATGGGTTCCTGTGGAGAAAAATGGTG
AAGAAAACAAAGATGATGATAATGTTTTCAGCAGCAATTTGCCCTCAGAGCCTGTGGACATCTCTACAGCAATGAGTGAACGGGCACTTG
CTCAGAAAAGACTCAGTGAGAATGCATTTGATCTTGAAGCCATGAGCATGTTAAATAGAGCTCAGGAAAGGATTGATGCCTGGGCTCAGC
TGAACTCTATTCCTGGCCAGTTCACAGGAAGTACAGGAGTACAGGTTTTGACACAAGAACAGTTGGCCAATACTGGTGCCCAAGCCTGGA
TTAAAAAGGATCAGTTCTTAAGAGCAGCCCCGGTAACTGGAGGAATGGGAGCCGTTTTGATGAGAAAAATGGGCTGGAGAGAAGGAGAAG
GATTAGGAAAAAACAAAGAAGGCAATAAGGAACCCATCCTAGTTGATTTTAAGACAGACCGAAAAGGTCTTGTTGCAGTAGGAGAAAGAG
CACAAAAGAGGTCTGGGAACTTCTCTGCTGCAATGAAAGATCTGTCAGGCAAACATCCTGTGTCTGCTTTGATGGAGATCTGTAATAAAA
GAAGGTGGCAACCACCTGAATTTCTATTGGTCCATGATAGTGGCCCTGATCATCGCAAACATTTTCTCTTTAGGGTATTGAGAAATGGAG
CCCTTACCAGACCCAATTGTATGTTTTTCTTGAATAGGTATTGATAAATGGAAGCGCTTACCAGCCCAGCTTTGCCAGCCCTAATAAGAA
GCATGCTAAAGCCACAGCAGCTACTGTGGTTCTTCAAGCAATGGGCCTTGTACCAAAGGACCTCATGGCTAATGCCACTTGCTTCAGGAG
TGCCTCACGTAGATAGATTGAGGTTTTATAATAATCATTTCAGAATTTTACTCTGCATCACAATGTATTTCCTCTTTAATGTTGTAAATA
TTTGGCAATTTAAGACATTGTGTAAAAAGCAATCTGTAAAAACATCTCCAGGCTTTGATTTTTGTACCATGGAAATTGTATTTAACCATA
CAGGGTTTTGGTATGTTTATATTGTTTACCTTAGTGATGTATTTGTTTAAGTGGCTAACATCCAAACGACTGTTTGAAGGCATCAGAGTA
ATCTTCAGTGTGGAATGTTAAATAACGCTTTTATACTGTATTTTGTACTATGATGTAACTCCCCTTCCTTATGGCTAGGCTACTGTAACA
CTTGCCTGTAATCAGTGAAGGGCTGTGCACCTTGTACTATTTCACAATGGGTTCTGCTGGACAGATAATGGGCCAGTGTTATTGAGGTGA
TCAAGATCTGTTCCACAGGGCTAATGCCACCATCTCCCCTCAAAATTTTGTAGAGGTTCTAAAAAGAAAGTGGTATGTTGTGTGATGATC
AGCACTAAGTCCTGCATTCCTGTTAAAGCCACTTGGGTCATAAGAAGGGAGTAAAAAATGAAGTCTGACTAGAATTCTATTGCAGAGGCC
AGTACATTTAGTATGGCATTGAGTTGTGATATAGTTTTACTTTGATGTGCATTTTGAATTTCAGCTACACCTAGATAGACGTAAAATGAT
AATTAAAATGCTGTAACCAACTTATCTAATAAAATTGGCAACCAGCCACTATTTTGTTGACTATGAGAAAGTTAAAAGTTTATGTTAATT
TTTAGGGTCTGATAGAATATTTCATGTGTATTACAGTGGTATTCATATGCTATGTCTCTAAACTTTATTTTCAAAAGCTTAAGGCCCAAA

>89078_89078_2_TAPBPL-SON_TAPBPL_chr12_6562443_ENST00000266556_SON_chr21_34925063_ENST00000356577_length(amino acids)=1273AA_BP=734
MVPAALPGSIWSSRNHIIFEASAPEGPALPTEQSALTAENTWPTEVPSSPSEESVSQPEPPVSQSEISEPSAVPTDYSVSASDPSVLVSE
AAVTVPEPPPEPESSITLTPVESAVVAEEHEVVPERPVTCMVSETPAMSAEPTVLASEPPVMSETAETFDSMRASGHVASEVSTSLLVPA
VTTPVLAESILEPPAMAAPESSAMAVLESSAVTVLESSTVTVLESSTVTVLEPSVVTVPEPPVVAEPDYVTIPVPVVSALEPSVPVLEPA
VSVLQPSMIVSEPSVSVQESTVTVSEPAVTVSEQTQVIPTEVAIESTPMILESSIMSSHVMKGINLSSGDQNLAPEIGMQEIALHSGEEP
HAEEHLKGDFYESEHGINIDLNINNHLIAKEMEHNTVCAAGTSPVGEIGEEKILPTSETKQRTVLDTYPGVSEADAGETLSSTGPFALEP
DATGTSKGIEFTTASTLSLVNKYDVDLSLTTQDTEHDMVISTSPSGGSEADIEGPLPAKDIHLDLPSNNNLVSKDTEEPLPVKESDQTLA
ALLSPKESSGGEKEVPPPPKETLPDSGFSANIEDINEADLVRPLLPKDMERLTSLRAGIEGPLLASDVGRDRSAASPVVSSMPERASESS
SEEKDDYEIFVKVKDTHEKSKKNKNRDKGEKEKKRDSSLRSRSKRSKSSEHKSRKRTSESRSRARKRSSKSKSHRSQTRSRSRSRRRRRS
SRSRSKSRGRRSVSKEKRKRSPKHRSKSRERKRKRSSSRDNRKTVRARSRTPSRRSRSHTPSRRRRSRSVGRRRSFSISPSRRSRTPSRR
SRTPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRRRSRSVVRRRSFSISPVRLRRSRTPLRRRFSRSPIRRKRSRSSERGRSPKRLTDL
DKAQLLEIAKANAAAMCAKAGVPLPPNLKPAPPPTIEEKVAKKSGGATIEELTEKCKQIAQSKEDDDVIVNKPHVSDEEEEEPPFYHHPF
KLSEPKPIFFNLNIAAAKPTPPKSQVTLTKEFPVSSGSQHRKKEADSVYGEWVPVEKNGEENKDDDNVFSSNLPSEPVDISTAMSERALA
QKRLSENAFDLEAMSMLNRAQERIDAWAQLNSIPGQFTGSTGVQVLTQEQLANTGAQAWIKKDQFLRAAPVTGGMGAVLMRKMGWREGEG
LGKNKEGNKEPILVDFKTDRKGLVAVGERAQKRSGNFSAAMKDLSGKHPVSALMEICNKRRWQPPEFLLVHDSGPDHRKHFLFRVLRNGA

--------------------------------------------------------------

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Fusion Gene PPI Analysis for TAPBPL-SON


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for TAPBPL-SON


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for TAPBPL-SON


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource